Kit for foaming topical skin preparations

Abstract

To provide a kit for obtaining a foaming topical skin preparation that improves skin condition and has a pleasant feel. [Solution] The present invention provides a kit for obtaining a foaming topical skin preparation, which is obtained by mixing an acidic substance, a carbon dioxide generating substance that reacts with the acidic substance to generate carbon dioxide, a thickener, and water, and is characterized by the incorporation of two or more thickeners in combination.

Description

Technical Field

[0001] The present invention relates to a kit for obtaining a foaming topical skin preparation.

Background Art

[0002] Conventionally, for cosmetic purposes, a gel-type foaming topical skin preparation has been proposed in which a carbonate and an acid are mixed in the presence of water and a thickener to generate carbon dioxide gas for use (see, for example, Patent Document 1).

Prior Art Documents

Patent Documents

[0003]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0004] However, studies on improving skin conditions such as increasing the water content of the skin, reducing the amount of water evaporation, and improving skin elasticity, as well as usability, stability, and feel of use, have not been sufficiently conducted. Moreover, almost no studies have been conducted on achieving both excellent improvement in skin conditions and feel of use.

[0005] In the present invention, various studies were conducted to obtain a composition that improves the skin condition and has a good feel of use in a foaming topical skin preparation. As a result, it was found that by combining and blending two or more thickeners, the above problems can be solved, and the present invention has been completed.

Means for Solving the Problems

[0006] The present invention provides a kit for obtaining a foaming topical skin preparation obtained by mixing an acidic substance, a carbon dioxide generating substance that reacts with the acidic substance to generate carbon dioxide, a thickener, and water, wherein the kit comprises two or more types of thickeners and further comprises one of the following configurations (1) to (3). (1) A solid composition (A) containing an acidic substance, and a composition (B) containing water, a thickener, and a carbon dioxide generating substance. (2) A solid composition (C) containing an acidic substance and a carbon dioxide generating substance, and a composition (D) containing water and a thickener. (3) A solid composition (E) containing a carbon dioxide generating substance, and a composition (F) containing water, a thickener, and an acidic substance. (However, this excludes cases where the thickeners in (B), (D), and (F) are in any of the following combinations: a combination of sodium alginate and xanthan gum, cellulose gum, hydroxypropyl methylcellulose, carbomer, polyvinyl alcohol, or bentonite; a combination of xanthan gum and cellulose gum, hydroxypropyl methylcellulose, or bentonite; or a combination of cellulose gum and hydroxypropyl methylcellulose or carbomer.)

[0007] Furthermore, the present invention provides the kit according to claim 1, characterized in that one or both of the compositions constituting the kit described in (1) to (3) further contain a polyhydric alcohol.

[0008] Furthermore, the present invention provides a kit for obtaining the effervescent topical skin preparation described in 1 or 2, characterized in that, among the kits described in (1) to (3) above, the solid composition ((A), (C), (E)) is in powder form, and the composition ((B), (D), (F)) containing water and a thickener is in gel form.

[0009] Furthermore, the present invention provides a kit for obtaining an effervescent topical skin preparation, characterized in that the thickening agents used in the kits described in (1) to (3) above are two or more selected from natural polysaccharides and / or cellulose-based thickening agents. [Effects of the Invention]

[0010] According to the present invention, by combining and blending two or more thickening agents, it is possible to provide a kit for obtaining a foaming topical skin preparation that improves skin condition by increasing skin moisture content, reducing transepidermal water loss, and improving skin elasticity, while also being excellent in terms of usability, safety, and stability, such as ease of mixing and application, and having a good feel. [Brief explanation of the drawing]

[0011] [Figure 1] Figure 1 shows the results of stratum corneum moisture content measurement for the comparative example and the example. [Figure 2] Figure 2 shows the results of moisture evaporation measurements for the comparative example and the example. [Figure 3] Figure 3 shows the results of elasticity measurements for the comparative example and the example. [Modes for carrying out the invention]

[0012] The following describes a kit for obtaining the foaming topical skin preparation of the present invention (hereinafter also referred to as "the kit") based on a preferred embodiment thereof.

[0013] The kit of the present invention has one of the following configurations (1) to (3). (1) A solid composition (A) containing an acidic substance, and a composition (B) containing water, a thickener, and a carbon dioxide generating substance. (2) A solid composition (C) containing an acidic substance and a carbon dioxide generating substance, and a composition (D) containing water and a thickener. (3) A solid composition (E) containing a carbon dioxide generating substance, and a composition (F) containing water, a thickener, and an acidic substance. In this specification, the solid composition of (1) is also referred to as (A), the aqueous composition of (1) as (B), the solid composition of (2) as (C), the aqueous composition of (2) as (D), the solid composition of (3) as (E), and the aqueous compound of (3) as (F).

[0014] The foaming topical skin preparation obtained using the kit of the present invention can be used in any form of cosmetics, quasi-drugs, or pharmaceuticals, but from the viewpoints of effectiveness and usability, it is preferably used as cosmetics or quasi-drugs (medicated cosmetics).

[0015] In addition, the foaming topical skin preparation obtained using the kit of the present invention can be topically applied to the skin including the scalp and hair, and can be used in various forms such as pack agents, hair growth agents, face wash agents, cleansing agents, lotions, emulsions, beauty gels, shampoos, conditioners, etc. When it is to be rinsed off, it is preferably used in pack agents, face wash agents, cleansing agents, shampoos, conditioners, etc.

[0016] First, each main constituent used in the kit for obtaining the foaming topical skin preparation of the present invention will be described.

[0017] <Acidic substance> As the acidic substance used in the present invention, any inorganic acid or organic acid that can be usually used as a topical preparation may be used, and one or more of these are used.

[0018] Examples of inorganic acids include phosphoric acid, potassium dihydrogen phosphate, sodium dihydrogen phosphate, sodium sulfite, potassium sulfite, sodium pyrosulfite, potassium pyrosulfite, sodium acid hexametaphosphate, potassium acid hexametaphosphate, sodium acid pyrophosphate, potassium acid pyrophosphate, sulfamic acid, and the like.

[0019] Examples of organic acids include linear fatty acids such as formic acid, acetic acid, propionic acid, butyric acid, and valeric acid or their salts, dicarboxylic acids such as oxalic acid, malonic acid, succinic acid, glutaric acid, adipic acid, pimelic acid, fumaric acid, maleic acid, phthalic acid, isophthalic acid, and terephthalic acid or their salts, acidic amino acids such as glutamic acid and aspartic acid or their salts, oxyacids such as glycolic acid, malic acid, tartaric acid, citric acid, lactic acid, hydroxyacrylic acid, α-oxybutyric acid, glyceric acid, tartronic acid, salicylic acid, gallic acid, tropic acid, ascorbic acid, and gluconic acid or their salts, and the like.

[0020] Among these, from the viewpoints of safety and solubility in water, citric acid, ascorbic acid, malic acid, and succinic acid are preferable.

[0021] The content of the acidic substance in (A), (C), and (F) of the present invention is preferably 0.01 parts by mass or more and 30 parts by mass or less, and more preferably 0.05 parts by mass or more and 20 parts by mass or less, based on 100 parts by mass of the total amount of the two agents of the corresponding kit. The amount of the skin external preparation referred to in this specification may be the amount at the start of mixing the components of each kit.

[0022] The content of the acidic substance in (A) of the present invention is preferably 0.1% by mass or more and 90% by mass or less, and more preferably 0.5% by mass or more and 80% by mass or less. The content of the acidic substance in (C) of the present invention is preferably 0.01% by mass or more and 50% by mass or less, and more preferably 0.05% by mass or more and 40% by mass or less. Furthermore, the content of the acidic substance in (F) of the present invention is preferably 0.01% by mass or more and 30% by mass or less, and more preferably 0.05% by mass or more and 20% by mass or less.

[0023] <Carbon dioxide generating substance> As the carbon dioxide generating substance used in the present invention, any substance that reacts with the acidic substance to generate carbon dioxide may be used.

[0024] Examples of the carbon dioxide generating substance include carbonates such as sodium carbonate, calcium carbonate, potassium carbonate, magnesium carbonate, and sodium sesquicarbonate, and hydrogen carbonates such as ammonium hydrogen carbonate, potassium hydrogen carbonate, sodium hydrogen carbonate, lithium hydrogen carbonate, cesium hydrogen carbonate, magnesium hydrogen carbonate, and calcium hydrogen carbonate. One or more of these may be used. Among these, hydrogen carbonates can be preferably used, and sodium hydrogen carbonate is more preferable in that it can achieve a moderate foaming power.

[0025] The carbon dioxide generating substance content in (B), (C), and (E) of the present invention is preferably 0.01 parts by mass or more and 30 parts by mass or less, and more preferably 0.05 parts by mass or more and 20 parts by mass or less, based on 100 parts by mass of the total amount of the two components of the kit.

[0026] The carbon dioxide generating substance content in (B) of the present invention is preferably 0.01% by mass or more and 30% by mass or less, and more preferably 0.05% by mass or more and 20% by mass or less. The carbon dioxide generating substance content in (C) of the present invention is preferably 0.01% by mass or more and 50% by mass or less, and more preferably 0.05% by mass or more and 40% by mass or less. The content of the carbon dioxide generating substance in (E) of the present invention is preferably 0.1% by mass or more and 90% by mass or less, and more preferably 0.5% by mass or more and 80% by mass or less.

[0027] <Thickening agent> The kit for obtaining the effervescent topical skin preparation of the present invention is characterized by the combination of two or more thickening agents. Such thickening agents are described in detail below. Examples of thickeners used in the present invention include various types that can be used in the fields of cosmetics and pharmaceuticals. For example, natural polysaccharides, cellulosic polymers, synthetic polymers, and clay minerals can be used.

[0028] The natural polysaccharides used in this invention refer to polysaccharides derived from plants, animals, or microbial fermentation that have not been subjected to processing aimed at reducing the size of the sugar. Polysaccharides undergo a slight size reduction during normal purification procedures. Such sugars remain natural. Only when polysaccharides are subjected to size reduction techniques are they considered to no longer be natural.

[0029] Specifically, examples include xanthan gum, succinoglycans, carrageenan, guar gum, locust bean gum, galactan, gum arabic, tragacanth gum, tamarind gum, agar, agarose, mannan, curdlan, alginic acid or its salts, gum arabic, pectin, quince seed, starch, algae colloid, chondroitin sulfate or its salts, chitosan and its derivatives, nucleic acids or their salts, ribonucleic acid or its salts, water-soluble proteins such as casein, collagen, gelatin, albumin, fibroin, elastin, keratin, and sericin, hyaluronic acid or its salts, and mucopolysaccharides such as chondroitin sulfate. Among these, xanthan gum, carrageenan, tamarind gum, alginic acid or its salts are preferred from the viewpoint of achieving both excellent usability and skin condition improvement effects.

[0030] The cellulosic polymer used in this invention is a polymer composed of cellulose or its derivatives as units. Specifically, examples include carboxymethylcellulose or its salts, methylcellulose, ethylcellulose, propylcellulose, hydroxymethylcellulose, hydroxyethylcellulose, hydroxypropylmethylcellulose, and sulfonated cellulose derivatives. Among these, carboxymethylcellulose or its salts, hydroxyethylcellulose, and hydroxypropylmethylcellulose are preferred from the viewpoint of achieving both excellent usability and skin condition improvement effects.

[0031] The synthetic polymers used in this invention are polymers artificially synthesized using monomers as constituent units. Specifically, examples include vinyl polymers such as carboxyvinyl polymers and polyvinyl alcohol; acrylic acid polymers such as acrylic acid / alkyl methacrylate copolymers, acrylates / alkyl acrylate crosspolymers, and polyacrylic acid; acrylamide polymers such as polyacrylamide and polyalkylacrylamide / polyacrylamide copolymers; Pluronic; and (PEG-240 / decyltetradeceth-20 / HDI) copolymers.

[0032] The clay minerals used in this invention refer to substances that are commonly known as the main component minerals that make up clay. Specifically, examples include laponite, bentonite, smectite kaolinite, and montmorillonite.

[0033] The combination of two or more thickening agents in the present invention is not particularly limited, but from the viewpoint of improving the feel of use and improving skin condition, a combination of two or more selected from natural polysaccharides and / or cellulose polymers is preferred, and a combination of one or more natural polysaccharides and one or more cellulose polymers is more preferred.

[0034] Specific examples of preferred combinations are as follows: (i) Examples of combinations of two or more natural polysaccharides include a combination of sodium alginate and at least one selected from tamarind gum and carrageenan, a combination of tamarind gum and at least one selected from carrageenan and xanthan gum, and a combination of carrageenan and xanthan gum. (ii) Examples of combinations of two or more cellulosic polymers include a combination of cellulose gum and at least one selected from hydroxyethylcellulose and hydroxypropylmethylcellulose stearoxy ether, and a combination of hydroxyethylcellulose and hydroxypropylmethylcellulose stearoxy ether. (iii) Examples of combinations of one or more natural polysaccharides and one or more cellulosic polymers include: a combination of sodium alginate and at least one selected from hydroxyethylcellulose and hydroxypropylmethylcellulose stearoxy ether; a combination of tamarind gum and at least one selected from cellulose gum, hydroxyethylcellulose and hydroxypropylmethylcellulose stearoxy ether; a combination of carrageenan and at least one selected from cellulose gum, hydroxyethylcellulose and hydroxypropylmethylcellulose stearoxy ether; and a combination of xanthan gum and at least one selected from hydroxyethylcellulose and hydroxypropylmethylcellulose stearoxy ether.

[0035] Among these, the combination described in (iii) above is considered the most preferable.

[0036] Among the more preferable combinations, the following combinations are particularly outstanding in terms of their individual effects while also providing a superior user experience and improving skin condition: It can be cited. From the perspective of increasing the moisture content of the stratum corneum,Combinations of carrageenan and hydroxyethylcellulose, and xanthan gum and hydroxyethylcellulose are particularly preferred. From the viewpoint of ease of mixing, the combination of carrageenan and hydroxypropyl methylcellulose stearoxy ether is particularly preferred. From the viewpoint of fineness of bubbles, the combination of carrageenan and cellulose gum is particularly preferred. From the viewpoint of sustained carbonation (fizzing sensation), the combination of carrageenan and cellulose gum is particularly preferred. From the viewpoint of skin moisturizing effect, combinations of xanthan gum and hydroxypropyl methylcellulose stearoxy ether, tamarind gum and cellulose gum, carrageenan and hydroxypropyl methylcellulose stearoxy ether, and carrageenan and hydroxypropyl methylcellulose stearoxy ether are particularly preferred. From the viewpoint of uniformity of bubbles, combinations of xanthan gum and hydroxyethylcellulose, tamarind gum and cellulose gum, carrageenan and hydroxyethylcellulose, and carrageenan and hydroxypropyl methylcellulose stearoxy ether are particularly preferred.

[0037] Furthermore, combinations that do not achieve both a good user experience and improved skin condition include: sodium alginate with xanthan gum, cellulose gum, hydroxypropyl methylcellulose, carbomer, polyvinyl alcohol, or bentonite; xanthan gum with cellulose gum, hydroxypropyl methylcellulose, or bentonite; or cellulose gum with hydroxypropyl methylcellulose or carbomer.

[0038] The amount of the thickener in (A), (B), (C), (D), (E), and / or (F) of the present invention is preferably 0.01 parts by mass or more and 40 parts by mass or less, and more preferably 0.1 parts by mass or more and 30 parts by mass or less, based on 100 parts by mass of the total amount of the two components of the kit. The amount of the thickener in the acid-containing composition and / or base-containing composition referred to here is the amount if one of them contains a thickener, and the total amount if both contain a thickener, and the same applies to the amount of the thickener in the acid and base-containing composition and / or aqueous composition.

[0039] The blending ratio of two or more thickening agents is preferably such that the content of any one of the other agents per 100 parts by mass of one agent is 1 part by mass or more and 10,000 parts by mass or less, more preferably 5 parts by mass or more and 5,000 parts by mass or less, and particularly preferably 10 parts by mass or more and 1,000 parts by mass or less.

[0040] <Water> The water that can be used in this invention is water that can be used in cosmetics, topical pharmaceuticals, quasi-drugs, etc., but purified water, distilled water, membrane filtered water, and ion-exchanged water are preferred.

[0041] The water content in the kits of (1) to (3) of the present invention is preferably 20 parts by mass or more and 95 parts by mass or less, and more preferably 30 parts by mass or more and 90 parts by mass or less, based on 100 parts by mass of the total amount of the two components of the kit.

[0042] <Polyhydric alcohols> In the present invention, it is preferable to include polyhydric alcohols in the topical skin preparation because they exhibit a high moisturizing effect and improve the feel of use. The polyhydric alcohols are not particularly limited as long as they can be used in topical preparations as usual, but examples include polyglycerins such as glycerin, diglycerin, triglycerin, and tetraglycerin; ethylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, propylene glycol, dipropylene glycol, polyethylene glycol, 1,3-propanediol, 1,2-pentanediol, sorbitol, polyglycerin derivatives; reducing sugars such as glucose, fructose, glyceraldehyde, lactose, arabinose, and maltose; and sugar alcohols such as erythritol, maltitol, sorbitol, and xylitol. One or more of these can be used in combination.

[0043] The polyhydric alcohol content in (A), (B), (C), (D), (E), and / or (F) of the present invention is preferably 1 part by mass or more and 80 parts by mass or less, and more preferably 5 parts by mass or more and 70 parts by mass or less, based on 100 parts by mass of the total amount of the two components of the kit. The amount of polyhydric alcohol referred to here is the amount of polyhydric alcohol if one of the kits contains it, and the total amount if both kits contain polyhydric alcohol.

[0044] <Other ingredients> The foaming topical skin preparation kit of the present invention may use one or more of the components commonly used in topical skin preparations, such as active ingredients, preservatives, pH adjusters, oils and fats, fragrances, colorants, antioxidants, antibacterial and antifungal agents, alcohols, surfactants such as nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants, inorganic salts, lubricants, and solvents. Furthermore, in the kit of the present invention, the added components may be used in either a solid composition or a aqueous composition, or in either one or both.

[0045] In the effervescent topical skin preparation kit of the present invention, when other components (components other than water, acidic substances, carbon dioxide generating substances, thickeners, and polyhydric alcohols) are included, it is preferable from the viewpoint of good effervescence and carbon dioxide retention that the total content of these components is 30% by mass or less, and particularly 25% by mass or less.

[0046] <Dosage form and amount of ingredients in the kit> Kits (1) to (3) will be described in more detail below. In kits (1) to (3), the dosage form of the solid composition in each kit can be a tablet, pellet, granule, fine granule, or powder. However, granules, fine granules, or powder are preferred from the viewpoint of ease of mixing with the other agent and cost during manufacturing.

[0047] Furthermore, while the aqueous composition of each kit can be in gel or liquid form, a gel form is preferred from the viewpoint of ease of use. The liquid agent has a viscosity at 25°C preferably less than 3000 mPa·s, and more preferably less than 4000 mPa·s. The gel-like agent has a viscosity at 25°C preferably 5000 Pa·s or more. This viscosity is measured, for example, by a viscometer (Brookfield RVT type). The amount of thickener in the liquid agent is preferably less than 0.05% by mass, more preferably less than 0.01% by mass, and particularly preferably less than 0.005% by mass. On the other hand, the amount of thickener in the gel-like agent is preferably 0.01% by mass or more, and more preferably 0.05% by mass or more.

[0048] <Solid composition of kits (1) to (3)> The preferred amounts of acid and carbon dioxide generating substance in the solid compositions of the kits (1) to (3) are as described above. The amount and content of the thickener in these compositions is preferably 0.01% to 20% by mass, particularly 0.05% to 15% by mass, when the other agent is in gel form, from the viewpoint of good foaming and carbon dioxide retention. When the other agent is in liquid form, it is preferably 0.01% to 30% by mass, particularly 0.05% to 25% by mass, when the other agent is in liquid form, from the viewpoint of ease of mixing with the liquid agent, foaming, and carbon dioxide retention.

[0049] The following methods can be used to granulate the solid compositions of kits (1) to (3).

[0050] When granules are obtained by granulating an acidic substance and / or a carbon dioxide generating substance as a mixture with other components, there are no particular restrictions on the content of the other components, but it is preferable that it be less than 95% by mass in the granules. If the other components are present in a content exceeding 95% by mass, the effervescence will be reduced, which is undesirable. The method for producing the above-mentioned powder or granules is not limited to this embodiment, and can be produced according to conventional methods such as dry crushing and granulation, wet crushing and granulation, fluidized bed granulation, high-speed stirring granulation, and extrusion granulation.

[0051] For example, in the production of granules, a matrix base material having functions such as granule molding may be used. When using a low-melting-point compound as the matrix base material, the carbon dioxide generating substance is added to the low-melting-point compound, which has been melted by heating in a container such as a beaker, and thoroughly stirred and mixed. Appropriate additives may be added as needed. This mixture is stirred further while gradually cooling at room temperature and left to stand until it solidifies. Once it has solidified to some extent, it may be rapidly cooled in a refrigerator or the like.

[0052] Alternatively, for example, the above material may be introduced into a fluidized bed granulator, mixed with airflow for several minutes, and then granulated by spraying water onto it.

[0053] If a low-melting-point compound is not used as the matrix base, the granulating agent is dissolved or dispersed in a suitable solvent such as water or ethanol in a container such as a beaker, the carbon dioxide generating substance is dissolved or dispersed in this mixture and thoroughly mixed, then heated in an oven or the like to remove the solvent and dry. Once completely solidified, it is crushed, sieved to standardize the particle size, and then obtained as granules.

[0054] <Hydrolyzed composition of kits (1) to (3)> The preferred amounts of carbon dioxide generating substance and acidic substance in the aqueous compositions ((B), (D), (F)) of kits (1) to (3) are as described above. Furthermore, the water content in the aqueous compositions of kits (1) to (3) is preferably 20% by mass or more, particularly 30% by mass or more, from the viewpoint of miscibility with the other agent ((A), (C), (E)) of each kit and foaming properties, and is preferably 95% by mass or less, particularly 90% by mass or less, from the viewpoint of improving the feel of use and improving skin condition.

[0055] In cases where the aqueous composition of the kits (1) to (3) contains a polyhydric alcohol, the proportion of the polyhydric alcohol in the aqueous composition is preferably 1% by mass or more, particularly 10% by mass or more, 80% by mass or less, particularly 70% by mass or less, and especially 60% by mass or less, which is preferable from the viewpoint of improving the feel of use and improving the condition of the skin.

[0056] Furthermore, each of the aqueous compositions (1) to (3) may contain humectants other than polyhydric alcohols, surfactants, pH adjusters, volatile alcohols, oils and fats, fragrances, plant and animal extracts, etc. For example, humectants other than polyhydric alcohols include polyoxyalkylene alkyl glucoside, sodium lactate, sodium pyrrolidone carboxylate, almond, avocado, marsh marigold, aloe, mallow, ononis, wild oat, licorice, quince seed, Sophora flavescens (Kujin), gardenia, grapefruit, watercress, gentian, Geranium thunbergii, burdock, wheat, Asarum sieboldii, cactus, soapwort, hawthorn, Rehmannia glutinosa, Spiraea japonica, and ginger. Examples of plant extracts include mallow, mulberry, thyme, cordyceps, houttuynia cordata, mint, coix seed, witch hazel, rose, cypress, coltsfoot, grape, prune, loofah, linden, hops, pine, quince, horse chestnut, lemon balm, cornflower, lily, lime, lavender, apple, rice and rice bran, blackcurrant, sedge, wild rose, Eleutherococcus senticosus, and seaweed, and one or more of these can be used.

[0057] The shape of the acidic substance and / or carbon dioxide generating substance can be irregular, planar, polyhedral, spherical, teardrop-shaped, fibrous, cylindrical, or fine powder, without any particular limitations. Furthermore, a wide range of particle sizes can be used without any particular limitations. In particular, a particle size distribution of approximately 1,000 μm or less is more preferable from the viewpoint of ease of handling and ease of mixing with viscous compositions. The particle size distribution in this invention can be determined by a conventional laser diffraction / scattering method.

[0058] In the case of the kit of (2), for example, a coating layer may be provided to enclose either the acidic substance and / or the carbon dioxide generating substance and the other components, or either the carbon dioxide generating substance and the other components, or either the carbon dioxide generating substance and the other components, or both may be encapsulated. Alternatively, the acidic substance and / or the carbon dioxide generating substance may be compressed and molded with a layer that does not contain the carbon dioxide generating substance, the acidic substance and the other components sandwiched between them or between the other components so that they do not come into direct contact with each other. Known methods can be used as means for the coexistence of the acidic substance and / or the carbon dioxide generating substance and the other components within the same agent.

[0059] In addition, the mixing ratio (mass ratio) of the two components in kits (1) to (3) is preferably 1:0.01 to 30, and more preferably 1:0.05 to 20.

[0060] In the composition obtained by the skin topical preparation kit of the present invention, the amounts of acidic substance, carbon dioxide generating substance, thickener, and water used are preferably 0.1 to 15% by mass for the acidic substance, 0.1 to 20% by mass for the carbon dioxide generating substance, 0.1 to 20% by mass for the thickener, and 40 to 99.6% by mass for the water, relative to their total amount. Furthermore, if the skin topical preparation contains a polyhydric alcohol, the amounts of acidic substance, carbon dioxide generating substance, thickener, water, and polyhydric alcohol used in the mixing to obtain the skin topical preparation are preferably 0.1 to 10% by mass for the acidic substance, 0.1 to 10% by mass for the carbon dioxide generating substance, 0.1 to 15% by mass for the thickener, 30 to 97% by mass for water, and 0.05 to 50% by mass for the polyhydric alcohol, relative to their total amount.

[0061] <Uses of topical skin preparation kits> The topical skin preparation according to the present invention promotes an increase in skin blood flow due to the action of carbon dioxide. The topical skin preparation according to the present invention is excellent in improving skin condition by increasing skin moisture content, reducing transepidermal water loss, and improving skin elasticity. Furthermore, the topical skin preparation according to the present invention is excellent in terms of usability during use (ease of mixing, smoothness of foam, fineness of foam, uniformity of foam, ease of application, resistance to dripping, foam elasticity, carbonation sensation and its duration, etc.) and in terms of usability after use (skin moisture, elasticity, brightness, redness, smoothness, suppleness, firmness, etc.). Furthermore, the topical skin preparation according to the present invention can be suitably used not only in cosmetics aimed at improving skin texture, rejuvenating skin, tightening skin, localized slimming, cleansing skin, conditioning skin, refining skin texture, keeping skin healthy, preventing rough skin, tightening skin, moisturizing skin, replenishing and retaining skin moisture and oil, maintaining skin flexibility, protecting skin, preventing skin dryness, softening skin, giving skin firmness, giving skin luster, smoothing skin, and reducing the appearance of fine lines caused by dryness, but also in quasi-drugs, pharmaceuticals, and other medicines aimed at preventing rough skin, chapped skin, heat rash, chilblains, cracks, chapped skin, and acne, oily skin, razor burn, preventing redness after sunburn or snowburn, tightening skin, cleansing skin, conditioning skin, keeping skin healthy, moisturizing skin, protecting skin, and preventing skin dryness. Furthermore, when used on the scalp and hair, it enhances the shine and smoothness of the hair, as well as the elasticity and moisturizing effect on the scalp. It can also be expected to promote the proliferation of hair papilla cells and hair growth due to its blood flow-improving properties. The topical skin preparation according to the present invention is preferably used as a cosmetic or quasi-drug, and is particularly preferred as a cosmetic or medicated cosmetic such as a lotion, cream, pack, or peeling agent. Among these, its use as a pack is especially preferable because it provides a pleasant feel and easily achieves a high level of skin condition improvement. [Examples]

[0062] The present invention will be described in more detail below with reference to examples, but the scope of the present invention is not limited to these examples. In each of the following examples and comparative examples, commercially available raw materials were used unless otherwise specified.

[0063] <Manufacturing of effervescent topical skin preparations> Each component listed in Tables 1 to 3 was formulated and mixed in the compositions shown in the same tables to produce the topical skin preparation kits for each example and comparative example. In Tables 1 to 3, acidic substances are also simply referred to as "acids," and carbon dioxide-generating substances are also simply referred to as "carbonates."

[0064] [Table 1]

[0065] [Table 2]

[0066] [Table 3]

[0067] The following [Evaluation 1] was performed on the above-mentioned examples and comparative examples. [Rating 1] Two healthy women in their 20s and 30s were randomly selected as subjects. Each subject's inner forearm was washed with facial cleanser and they rested quietly in the measurement room for 15 minutes. Next, the amount of water evaporation, stratum corneum moisture content, and elasticity were measured in a 4cm x 4cm measurement area where the effervescent topical skin agent was to be applied, using the method described below. Then, the effervescent topical skin agent was applied to the measurement area and left to stand for 10 minutes. After that, the effervescent topical skin agent was removed and the area was washed with water. Fifteen minutes after washing, the same measurements were taken after the application of the effervescent topical skin agent. The subjects remained quietly in the measurement room during the measurements. Figures 1 to 3 show the results of skin condition measurements after use. Note that the values ​​in Figures 1 to 3 are relative values ​​(rate of change) with the measurement value before application of the foaming topical skin agent set to 1. A smaller value for transepidermal water loss indicates a better barrier function, a larger value for stratum corneum moisture content indicates better performance, and a larger value for elasticity indicates better performance.

[0068] The skin condition before and after application of the foaming topical skin preparation was measured using the following devices. These measurements were performed according to the standard methods described in the instruction manual included with the devices. • Transepidermal water loss: Measured using the Tevameter™300 (CK Corporation). • Stratum corneum moisture content: Measured using the SKICON-200EX skin surface stratum corneum moisture content measuring device (manufactured by IBS Corporation). This skin surface stratum corneum moisture content measuring device evaluates the moisture content of the stratum corneum by measuring the conductance (electrical conductivity, unit: μS) of the skin. • Elasticity: Measured using a skin viscoelasticity measuring device, Cutometer MPA580 (manufactured by Courage+Khazaka).

[0069] As shown in Figures 1 to 3, the effervescent topical skin preparations of each example, which were formulated with a combination of two or more specific thickening agents, showed a greater increase in stratum corneum moisture content and elasticity, and a smaller decrease in transepidermal water loss, compared to the effervescent topical skin preparations of each comparative example that did not contain this combination of thickening agents. Furthermore, as is clear from Examples 1 to 3, all kits with configurations (1) to (3) showed a high skin condition improvement effect. Therefore, it is clear that the effervescent topical skin preparations of the present invention, formulated with a combination of two or more specific thickening agents, have a high skin condition improvement effect.

[0070] The following [Evaluation 2] was performed on the above examples and comparative examples. [Rating 2] Two healthy women in their 20s and 30s were randomly selected as subjects. Each subject's inner forearm was cleansed with facial cleanser, and they rested quietly in the measurement room for 15 minutes. Next, the effervescent topical skin agent was applied to the measurement site and left for 10 minutes. Then, the effervescent topical skin agent was removed, and the area was washed with water. Evaluations were conducted on 16 evaluation items during and after use, based on a 7-point scale. The evaluation criteria are shown in Table A below, and the results are shown in Tables B to D below. Note that the results below represent the average of the evaluation scores of the two subjects.

[0071] [Table A]

[0072] [Table B]

[0073] [Table C]

[0074] [Table D]

[0075] As shown in Tables B to D, the effervescent topical skin preparations of each example, which were formulated with a combination of two or more specific thickeners, were superior to the effervescent topical skin preparations of each comparative example that did not contain these thickeners in terms of usability during application (ease of mixing, smoothness of foam, fineness of foam, uniformity of foam, ease of application, resistance to dripping, elasticity of foam, carbonation sensation and its duration), as well as superior after-use feel (moisture, elasticity, brightness, redness, smoothness, suppleness, and firmness of the skin). Furthermore, as is clear from Examples 1 to 3, all kits with configurations (1) to (3) exhibited superior usability.

[0076] Therefore, it is clear that the foaming topical skin preparation of the present invention, formulated in combination with two or more specific thickening agents, possesses both excellent skin condition improving effects and a pleasant user experience.

Claims

1. A kit for obtaining a foaming topical skin preparation obtained by mixing an acidic substance, a carbon dioxide generating substance that reacts with the acidic substance to generate carbon dioxide, a thickener, and water, wherein the kit comprises two or more types of thickeners and further comprises one of the following configurations (2) to (3): The kit wherein the thickening agent is a combination of carboxymethylcellulose sodium and hydroxyethylcellulose, and further comprises the following components (2) and (3). (2) A solid composition (C) containing an acidic substance and a carbon dioxide generating substance, and a composition (D) containing water and a thickener. (3) A solid composition (E) containing a carbon dioxide generating substance, and a composition (F) containing water, a thickener, and an acidic substance.

2. The kit according to claim 1, characterized in that one or both of the compositions constituting the kit further contain a polyhydric alcohol.

3. A kit for obtaining an effervescent topical skin preparation according to claim 1 or 2, characterized in that the solid composition ((C), (E)) is in powder form, and the composition ((D), (F)) containing water and a thickener is in gel form.

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