Nanoemulsion composition

Abstract

To provide a nanoemulsion composition that has a good moisturizing effect and sustained moisturizing effect. [Solution] The nanoemulsion composition comprises (A) 0.001 to 10% by mass of vitamins and / or their derivatives, (B) 0.01 to 5% by mass of a hydrocarbon oil that is liquid at room temperature, (C) sodium polyoxyethylene oleyl ether phosphate, (D) ethylene oxide (polyethylene glycol) type nonionic surfactant, (E) 1 to 20% by mass of glycerin, and (F) water, forming an emulsion, the particle size of the emulsion being 300 nm or less.

Description

Technical Field

[0001] The present invention relates to a nano-emulsion cosmetic composition having good moisturizing feeling and persistence.

Background Art

[0002] A variety of cosmetics are provided in the market for skin care. There are, for example, lotions, milks, cream preparations for moisturizing, and for skin problems, spot care and whitening cosmetics containing, for example, tranexamic acid, arbutin, vitamin C, retinol-containing cosmetics for wrinkle and sagging care, niacinamide-containing cosmetics, and preparations for rough and dry skin care containing dipotassium glycyrrhizinate, rice power No. 11, etc.

[0003] These various cosmetics used for the skin of the face, body, etc. each have characteristics selected by users, and it is of course required that they are not sticky either during or after use, and have a moisturizing effect. Furthermore, the persistence of the effect and the actual feeling thereof are required regardless of short-term use or long-term continuous use. In order to obtain a moisturizing effect and a lasting feeling of moisture, for example, an emulsified composition containing ceramides, alkylene oxide derivatives, etc., which are essential components of the skin (Patent Document 1), an emulsified composition combining an oily component having a melting point of 50 to 150°C, octamethyltrisiloxane, an α-olefin oligomer and a nonionic surfactant (Patent Document 2), a cosmetic composition containing nicotinic acid amide, cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol, a surfactant, a liquid oil and a polyhydric alcohol having an IOB value of 2.2 to 3.4 (Patent Document 3) have been proposed.

[0004] Furthermore, emulsion formulations have been proposed by various companies to improve the persistence of moisturizing effects and other properties in cosmetics. Emulsion formulations disperse oil in a water-based formulation in the form of fine particles (oil droplets). Unlike water-soluble texture modifiers and moisturizers such as polyols, the oil contained in emulsion formulations remains on the skin for a long time, contributing to its sustained effect. However, it is difficult to make oil exist as an emulsion in water-based formulations such as lotions, and it is necessary to utilize surfactants. Examples of emulsion formulations that use surfactants to form a stable emulsion include a composition using a specific nonionic surfactant and an anionic surfactant selected from acyl glutamates containing 14 to 18 carbon atoms in the acyl group (Patent Document 4), and an oil-in-water emulsion cosmetic containing an oily component, a polyglycerin fatty acid ester nonionic surfactant with an HLB of 10 or higher, and an anionic surfactant in a specific ratio and an aqueous component (Patent Document 5).

[0005] However, the emulsion formulations disclosed in Patent Documents 4 and 5 do not fully satisfy the moisturizing effect or the duration of that moisturizing effect. Therefore, there is a need for an emulsion formulation that provides a good moisturizing effect and sustained moisturizing effect while maintaining the emulsion's stability. [Prior art documents] [Patent Documents]

[0006] [Patent Document 1] Japanese Patent Publication No. 2024-105720 [Patent Document 2] Japanese Patent Publication No. 2023-165033 [Patent Document 3] Patent No. 7071830 [Patent Document 4] Patent No. 7389136 [Patent Document 5] Japanese Patent Publication No. 2023-8460 [Overview of the Initiative] [Problems that the invention aims to solve]

[0007] In view of the above circumstances, the object of the present invention is to provide a nanoemulsion composition that has a good moisturizing effect and sustained moisturizing effect. [Means for solving the problem]

[0008] As a result of diligent research to achieve the objective, the inventors have found that the objective can be solved by having the following specific features of the invention.

[0009] The nanoemulsion composition according to the present invention comprises (A) 0.001 to 10% by mass of vitamins and / or their derivatives, (B) 0.01 to 5% by mass of a hydrocarbon oil that is liquid at room temperature, (C) sodium polyoxyethylene oleyl ether phosphate, (D) ethylene oxide (polyethylene glycol) type nonionic surfactant, (E) 1 to 20% by mass of glycerin, and (F) water, forming an emulsion, the particle size of the emulsion being 300 nm or less.

[0010] Furthermore, the nanoemulsion composition according to the present invention may have a total amount of component (A) and component (B) ((A) + (B)) of 0.1 to 11% by mass, a ratio of the amount of component (B) to the amount of component (C) ((B):(C)) of 1:0.1 to 1:5, and a total amount of component (C) and component (D) ((C) + (D)) of 0.1 to 11% by mass.

[0011] Furthermore, the nanoemulsion composition according to the present invention may also have component (A) be one or more selected from retinol, tocopherol, niacinamide, pantothenic acid, cyanocobalamin, biotin, ascorbic acid 2-glucoside, and ascorbyl palmitate. [Effects of the Invention]

[0012] The nanoemulsion composition according to the present invention can provide a good moisturizing sensation and sustained moisturizing effect. [Modes for carrying out the invention]

[0013] The following describes in detail nanoemulsion compositions according to embodiments of the present invention, but the present invention is not limited to the following embodiments. The present invention is not limited to each of the configurations described below, and various modifications are possible within the scope of the claims, and embodiments and examples obtained by appropriately combining the technical means disclosed in different embodiments and examples are also included in the technical scope of the present invention. Furthermore, unless otherwise specified in this specification, "A to B" representing a numerical range means "greater than or equal to A and less than or equal to B".

[0014] <Nanoemulsion composition> The nanoemulsion composition according to this embodiment contains at least components (A) to (F) below and forms an emulsion. The particle size of the formed emulsion is 300 nm or less. (A) Vitamins and / or derivatives thereof (B) Liquid hydrocarbon oil at room temperature (C) Sodium polyoxyethylene oleyl ether phosphate (D) Ethylene oxide (polyethylene glycol) type nonionic surfactant (E) Glycerin (F)Water

[0015] Component (A) of the nanoemulsion composition according to this embodiment is one or more vitamins and / or derivatives thereof. Vitamins are one of the five major nutrients necessary for the survival and growth of living organisms: proteins, lipids, carbohydrates, vitamins, and minerals, and are organic compounds necessary for maintaining the normal functions of the human body. The functions of vitamins are wide-ranging; for example, in humans, they are compounds that are said to have functions such as helping other nutrients work efficiently, assisting metabolism, and improving immunity, as well as antioxidant and anti-aging effects that help maintain beautiful skin and hair. Thirteen types of vitamins are recognized in humans. Vitamins are found in many plant-based foods such as vegetables and fruits, as well as in many animal-based foods, and are divided into two types: fat-soluble vitamins and water-soluble vitamins. Fat-soluble vitamins include vitamin A, vitamin D, vitamin E, and vitamin K, while water-soluble vitamins include vitamin C and the vitamin B group (B1, B2, B3, B6, B7, B9, B12, etc.). Examples of vitamins and their derivatives include retinol (vitamin A), tocopherol (vitamin E), niacinamide (vitamin B3), pantothenic acid (vitamin B5), cyanocobalamin (vitamin B12), ascorbic acid 2-glucoside (vitamin C), and ascorbyl palmitate (vitamin C). (A) Commercially available vitamins and / or their derivatives can be used as components.

[0016] In the nanoemulsion composition according to this embodiment, vitamins and / or their derivatives may be used alone or in combination of two or more. The amount of component (A) is 0.001 to 10% by mass of the total composition of the nanoemulsion composition, preferably 0.01 to 5% by mass. If the amount of component (A) is in the range of 0.001 to 10% by mass of the total composition of the cosmetic composition, a skin moisturizing effect can be obtained.

[0017] Component (B) of the nanoemulsion composition according to this embodiment is a hydrocarbon oil that is liquid at room temperature (for example, 25°C). Component (B) is not particularly limited as long as it is liquid at room temperature. Examples thereof include liquid paraffin, hydrogenated polyisobutene, α-olefin oligomer, squalane, etc., and an oil agent that is widely used in cosmetics, moisturizers, ointments, etc. can be used. A hydrocarbon oil that is liquid at room temperature as component (B) can be a commercially available product.

[0018] In the nanoemulsion composition according to this embodiment, the hydrocarbon oil that is liquid at room temperature may be used alone or in combination of two or more. The blending amount of component (B) is 0.01 to 5% by mass in the total composition of the cosmetic composition, and preferably 0.1 to 1% by mass. If the blending amount of component (B) is 0.01 to 5% by mass in the total composition of the cosmetic composition, a sufficient moist feeling and good persistence can be obtained.

[0019] Component (C) of the nanoemulsion composition according to this embodiment is sodium polyoxyethylene oleyl ether phosphate. Sodium polyoxyethylene oleyl ether phosphate is also known as Diores-8 phosphate Na, and is an anionic surfactant (anionic surfactant) having a phosphate Na and a polyoxyethylene chain as hydrophilic groups. Sodium polyoxyethylene oleyl ether phosphate exhibits emulsifying power, solubilizing power, and dispersing power in a wide pH range. Commercially available products can be used for sodium polyoxyethylene oleyl ether phosphate, and specific examples include, for example, NIKKOL DOP-8NV (manufactured by Nikko Chemicals Co., Ltd.).

[0020] In the nanoemulsion composition according to this embodiment, the blending amount of component (C) can be appropriately determined and used within the range of an effective amount. The preferable blending amount of component (C) in the nanoemulsion composition according to this embodiment is 0.01 to 10% by mass.

[0021] Component (D) of the nanoemulsion composition according to this embodiment is ethylene oxide (polyethy This is a nonionic surfactant of the polyethylene glycol type, obtained by adding ethylene oxide as a hydrophilic group. Examples of ethylene oxide (polyethylene glycol) type nonionic surfactants include polyoxyethylene alkyl ethers, polyoxyethylene steryl ethers, polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene fatty acid esters, polyoxyethylene polyhydric alcohol fatty acid esters, polyoxyethylene hydrogenated castor oil, and polyoxyethylene sorbitan fatty acid esters. Component (D) is not particularly limited, but is preferably a polyoxyethylene polyhydric alcohol fatty acid ester. Specific examples of polyoxyethylene polyhydric alcohol fatty acid esters include polyoxyethylene glyceryl isostearate, polyoxyethylene glyceryl triisostearate, polyoxyethylene coconut oil fatty acid glyceryl, polyoxyethylene (caprylic / capric acid) glyceryl, and polyoxyethylene sorbitan tetraoleate.

[0022] In the nanoemulsion composition according to this embodiment, the amount of component (D) can be appropriately determined and used within the range of an effective amount. The preferred amount of component (D) in the nanoemulsion composition according to this embodiment is 0.01 to 10% by mass.

[0023] Component (E) of the nanoemulsion composition according to this embodiment is glycerin. Generally, glycerin is widely used as a texture modifier and humectant. Glycerin is a type of trihydric alcohol, specifically a trihydric alcohol (polyhydric alcohol) with three hydroxyl groups in its chemical structure. It exhibits very high hygroscopicity, provides a moist feel to the skin, and is widely used as a humectant. In nature, it is widely present in the oils and fats of animals and plants, including humans, as glycerides, which are esters with fatty acids. By containing glycerin as component (E) in the nanoemulsion composition according to this embodiment, it is possible to improve the feeling of moisture and other properties.

[0024] In the nanoemulsion composition according to this embodiment, the amount of component (E) can be appropriately determined and used within an effective range, preferably 1 to 20% by mass.

[0025] The water, which is component (F) of the nanoemulsion composition according to this embodiment, can be ion-exchanged water, purified water, tap water, natural water, etc., and can be freely adjusted and blended according to the dosage form and form of the nanoemulsion composition according to this embodiment. Specifically, in the production of the nanoemulsion composition, after adjusting with a portion of the water to be blended, the remaining water may be blended in multiple stages as a residue, taking into consideration the dosage form and form.

[0026] In the nanoemulsion composition according to this embodiment, the total amount of component (A) and component (B) may be 0.1 to 11% by mass, the ratio of the amount of component (B) to the amount of component (C) ((B):(C)) may be 1:0.1 to 1:5, and the total amount of component (C) and component (D) ((C)+(D)) may be 0.1 to 11% by mass. By setting the total amount of component (A) and component (B), the ratio of the amount of component (B) to component (C), and the total amount of component (C) and component (D) within the above ranges, a more stable emulsion can be obtained.

[0027] The nanoemulsion composition according to this embodiment contains the above components (A) to (F) and forms an emulsion. The particle size of the formed emulsion is 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less, and even more preferably 50 nm or less. By containing the above components (A) to (F) and setting the particle size of the formed emulsion to 300 nm or less, the nanoemulsion composition can provide the skin with a good moisturizing sensation and sustained moisturizing effect when used. Furthermore, the nanoemulsion composition according to this embodiment can be used according to the purpose. By adjusting the particle size, nanoemulsions with a specific appearance and good stability can be obtained. In nanoemulsion compositions, the larger the particle size of the emulsion, the higher the turbidity. At around 300 nm, it has a whitish appearance; at around 200 nm, it has a slightly translucent, cloudy white appearance; at around 100 nm, it has a semi-transparent, bluish appearance; and at around 50 nm, it has a nearly transparent appearance.

[0028] In this specification, "particle diameter" refers to the average particle diameter. Therefore, a particle diameter of 300 nm or less means that the average particle diameter is 300 nm or less. Furthermore, the particle diameter of an emulsion can be measured by conventionally known methods, such as dynamic light scattering.

[0029] The nanoemulsion composition according to this embodiment may further contain fragrances, antibacterial agents, preservatives, amino acids, bactericidal agents, UV absorbers and surfactants, polymers, texture modifiers, etc., and one or more of these can be used in combination. The amount of each is not particularly limited, but can be determined as appropriate, preferably within the range of an effective amount. [Examples]

[0030] The present invention will be specifically described below with reference to examples, but the scope of the invention is not limited by these examples. The test methods for moisturizing effect and duration (sustainability) described in the examples are shown below. The amounts of the cosmetic compositions shown in the table below are expressed in mass percent.

[0031] (Moisture feeling) Five expert panelists applied one pump of each cosmetic composition shown in the examples and comparative examples, and conducted a sensory test regarding the moisturizing sensation. The evaluation was performed according to the following criteria.

[0032] Criteria for evaluation (moisturizing effect present, absent) ◎: Moisturizing (5 people) ○: Provides a moisturizing feeling (4 people) △: Provides a moisturizing effect (3 people) ×: Moisturizing effect, but used by 2 people or less

[0033] (Longevity / sustainability of moisturizing effect) Five expert panelists applied one pump of each cosmetic composition shown in the examples and comparative examples, and conducted a sensory test regarding the duration and persistence of the moisturizing effect. The evaluation was performed according to the following criteria.

[0034] Criteria for evaluation (persistence / sustainability present, absent) ◎: 5 people felt it was persistent or had a lasting effect. ○: Four people felt that it was persistent or had a lasting effect. △: 3 people felt it was persistent or had a lasting effect. ×: More than 3 people feel that the effect is not lasting or doesn't last.

[0035] (Measurement of emulsion particle size) The particle size of the emulsions in each sample of the examples and comparative examples was measured using a HORIBA LB-550 dynamic light scattering particle size distribution analyzer.

[0036] [Table 1]

[0037] [Table 2]

[0038] As shown in Tables 1 and 2, Examples 1 to 8 were superior to Comparative Examples 1 to 5 in terms of moisturizing sensation upon application and the duration of that moisturizing sensation.

[0039] Below, Example 9 is given as another example of a nanoemulsion composition according to this embodiment. The cosmetic composition of Example 9 was also examined for the moisturizing sensation upon application and the persistence of that moisturizing sensation, and it was found to be excellent in Example 9 as well.

[0040] Example 9 (Mist Toner) Amount of ingredients (mass %) (1) Squalane 0.5% (2) Medium oil (liquid paraffin) 0.5% (3) Glycerin 5.0% (4) Polyoxyethylene glyceryl triisostearate 1.5% (5) Sodium polyoxyethylene oleyl ether phosphate 0.3% (6) Pure water 3.0% (7) Tocopherol 0.01% (8) Sodium hyaluronate 0.5% (9) Proteoglycan 0.1% (10) Betaine 0.5% (11) BG 5.0% (12) Hydroxypropyl methylcellulose 0.01% (13) Ethanol 5.0% (14) Salicylic acid 0.001% (15) Nicotinamide 0.5% (16) Lemon fruit extract 0.5% (17) Hydrogenated lecithin 0.1% (18) EDTA-2Na 0.01% (19) Polyethylene glycol 1.0% (20) Phenoxyethanol 0.5% (21) Hydrolyzed collagen 0.1% (22) Centella Asiatica Extract 0.1% (23) Citric acid 0.01% (24) Rice fermentation liquid 0.5% (25) Parabens (appropriate amount) (26) Pure water remaining

[0041] (Manufacturing method) Mix (1) to (7) uniformly and disperse to prepare base A. Then, add (8) to (26) while stirring uniformly and disperse to prepare the mist lotion, and then fill into a container to obtain the lotion.

Claims

1. (A) Vitamins and / or derivatives in an amount of 0.001 to 10% by mass, (B) A liquid hydrocarbon oil at room temperature in a quantity of 0.01 to 5% by mass, (C) Sodium polyoxyethylene oleyl ether phosphate, (D) Ethylene oxide (polyethylene glycol) type nonionic surfactant, (E) Glycerin in a quantity of 1 to 20% by mass, (F) Water and, A nanoemulsion composition that forms an emulsion, with the particle size of the emulsion being 300 nm or less.

2. The sum of the amounts of component (A) and component (B) ((A) + (B)) is between 0.1 and 11% by mass. The ratio of the amount of component (B) to the amount of component (C) ((B):(C)) is 1:0.1 to 1:

5. The nanoemulsion composition according to claim 1, wherein the sum of the amounts of component (C) and component (D) ((C) + (D)) is 0.1 to 11% by mass.

3. The nanoemulsion composition according to claim 1 or 2, wherein component (A) is one or more selected from retinol, tocopherol, niacinamide, pantothenic acid, cyanocobalamin, biotin, ascorbic acid 2-glucoside, and ascorbyl palmitate.

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