Compositions and methods for improving indigestible fiber utilization in animals

Lysozyme supplementation in animal feeds addresses the negative effects of insoluble fiber by improving non-digestible fiber utilization and nutrient digestibility, enhancing growth performance and health in non-human animals.

JP2026500786APending Publication Date: 2026-01-08ELANCO US INC
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Patent Information

Application Number
JP2025538489
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2022-12-28
Filing Date
2023-12-21
Publication Date
2026-01-08

AI Technical Summary

Technical Problem

Insoluble fiber in animal feeds negatively impacts intestinal health, increases the incidence of swine dysentery, reduces the presence of beneficial lactic acid-producing bacteria, and affects the digestibility of amino acids and other nutrients, with inconsistent responses to carbohydrase supplementation.

Method used

The use of lysozyme, specifically C-type or GH-22 lysozyme, in animal feed compositions to improve the utilization of non-digestible fiber, reducing its anti-nutritional effects and enhancing nutrient digestibility and growth performance.

Benefits of technology

Lysozyme supplementation improves non-digestible fiber utilization by up to 36%, reduces undigested fiber by 13%, enhances nutrient digestibility, and improves growth performance without affecting pathogen growth, leading to better health outcomes in non-human animals.

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Abstract

The present disclosure provides compositions and methods for improving non-digestible fiber (NDF) utilization and reducing anti-nutritional effects in animal feed. The methods include orally administering a composition containing lysozyme to an animal. More specifically, the methods include orally administering a composition containing lysozyme, C-type lysozyme, or GH-22 lysozyme to an animal. The methods and compositions can be used to improve NDF utilization, growth performance, viability, or any combination thereof in non-human animals.
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