Patch manufacturing method and manufacturing device

Abstract

To provide a manufacturing method and a manufacturing device of a patch capable of appropriately cooling plaster supplied on a support or on a liner.SOLUTION: A manufacturing method of a patch includes: a spreading step of supplying plaster on one of continuous support 103 and liner 101 to form a plaster layer 102; a stacking step of forming a stacking body 100 by placing the other of the support 103 and liner 101 on the plaster layer 102; and a winding step of forming a roll-shaped intermediate roll 104 by winding the stacking body 100. The manufacturing method further includes a cooling step of air-cooling the plaster layer 102 between the spreading step and the winding step.SELECTED DRAWING: Figure 2

Description

[Technical field]

[0001] The present invention relates to a method and an apparatus for producing a patch. [Background technology]

[0002] There are known methods and apparatuses for producing patches such as tapes or poultices which have a backing, a paste layer which is an adhesive formed on the backing and contains an active ingredient such as a medicinal ingredient, and a peelable liner which protects the paste layer (for example, Patent Document 1).

[0003] In the process of manufacturing a patch, one of a series of supports or liners is transported, and a paste is supplied onto the transported support or liner to form a paste layer. The other of the support or liner is then placed on the paste layer and integrated, and then wound up to form a roll of intermediate body. In the next process, the laminate of the intermediate body roll is cut to a predetermined size and shape as it is unwound. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] International Publication No. 2007 / 021008 Summary of the Invention [Problem to be solved by the invention]

[0005] If the temperature of the intermediate roll is high when cutting the intermediate roll, the paste layer disposed between the support and the liner is likely to stick to the cutting blade, etc. As a result, the cutting device may stop, etc., resulting in a problem of reduced production efficiency. In addition, if the temperature of the intermediate roll is high, the viscosity of the paste may decrease, causing the paste to permeate the support composed of a mesh material such as a nonwoven fabric or knit, and it may become impossible to control the thickness of the paste layer, and therefore the thickness of the patch, to an appropriate thickness.

[0006] An object of the present invention is to provide a method and apparatus for producing a patch, which is capable of appropriately cooling a paste layer supplied onto a support or a liner. [Means for solving the problem]

[0007] According to one aspect of the present invention, there is provided a method for producing a patch, comprising a spreading step of supplying a paste onto one of a series of supports or liners to form a paste layer, a lamination step of placing the other of the support or the liner on the paste layer to form a laminate, and a winding step of winding up the laminate to form a roll-shaped intermediate roll, the method being characterized by further comprising a cooling step of air-cooling the paste layer between the spreading step and the winding step.

[0008] According to another aspect of the present invention, there is provided an apparatus for manufacturing a patch, comprising: a spreading device for supplying a paste onto one of a series of supports or liners to form a paste layer; a laminating device for placing the other of the supports or liners on the paste layer to form a laminate; and a winding device for winding up the laminate to form a roll-shaped intermediate roll, characterized in that a cooling device for air-cooling the paste layer is further provided between the spreading device and the winding device.

[0009] The cooling step may be performed between the spreading step and the laminating step. The cooling step may be performed between the laminating step and the winding step. Effect of the Invention

[0010] The aspects of the present invention have a common effect of providing a method and an apparatus for producing a patch that can appropriately cool a paste supplied onto a support or a liner. [Brief description of the drawings]

[0011] [Figure 1] FIG. 1 is a schematic diagram of a patch manufacturing apparatus according to an embodiment of the present invention. [Diagram 2] FIG. 2 is an enlarged view of part A in FIG. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0012] Hereinafter, an embodiment of the present invention will be described in detail with reference to the drawings. Fig. 1 is a schematic diagram of a patch manufacturing apparatus 1 according to an embodiment of the present invention, and Fig. 2 is an enlarged view of part A in Fig. 1.

[0013] 1 and 2, the patch manufacturing apparatus 1 has a spreading device 2 that supplies a paste onto a series of conveyed liners 101 to form a paste layer 102, a laminating device 3 that places a support 103 on the paste layer 102 to form a laminate 100, and a winding device 4 that winds up the laminate 100 to form a roll-shaped intermediate roll 104, and further has a cooling device 5 between the spreading device 2 and the winding device 4 that air-cools the paste layer 102. Details will be described below. Although not shown, in a cutting process or cutting device downstream of the winding device 4, the laminate 100 of the intermediate roll 104 is cut into a predetermined size and shape while being unwound.

[0014] The liner 101 is a continuous strip-shaped member made of, for example, polyethylene terephthalate. In the patch manufacturing apparatus 1, the liner 101 is transported to the spreading apparatus 2 from a process or device upstream of the spreading apparatus 2. The paste constituting the paste layer 102 is an adhesive containing an active ingredient such as a medicinal ingredient. The paste is supplied to a hopper after being melted in the immediately preceding preparation process, kept warm in the paste supply section 10, and supplied onto the liner 101 from a supply port. Specifically, the paste is supplied from the paste supply section 10 on a backup roll 11 to the sequentially transported liners 101, and spread to a uniform thickness. Any material may be used for the liner 101 as long as it is peelably adhered to the paste layer 102.

[0015] The paste layer 102 formed on the liner 101 is cooled by the cooling device 5. The cooling device 5 is disposed downstream of the paste supply section 10, for example, near the backup roll 11. The cooling device 5 emits cold air C to the liner 101, and cools the paste layer 102 through the liner 101. Since the paste layer 102 is not directly exposed to the cold air C, more uniform cooling is possible, and the thickness of the paste layer 102 is prevented from being unevenly changed due to the cold air. The cooling device 5 cools the paste layer 102 immediately after the paste is spread, that is, near the backup roll 11, to increase the viscosity of the paste, thereby making it less susceptible to external influences on the paste during transport to downstream processes or devices. The thickness of the paste layer 102 is measured by a thickness sensor 20. The heat exhausted from the paste layer 102 by the cooling of the cooling device 5 is discharged to the outside by a ventilation device 21.

[0016] Next, the liner 101 and paste layer 102 transported via transport rolls 12 are temporarily heated by heating rolls 13. Immediately after the liner 101 and paste layer 102 are heated, the support 103, which is unwound by nip rolls 16 via unwinding rolls 14 and 15, is placed on the paste layer 102 to form the laminate 100. In other words, the laminate 100 is a series of strip-shaped members in which the paste layer 102 is placed between the support 103 and the liner 101. The support 103 is composed of a mesh such as a nonwoven fabric or knit.

[0017] Next, the laminate 100 is transported while being gradually cooled via the transport roll 12 and the cooling rolls 17 and 18, and is cooled again by the cooling device 5. Specifically, the cooling device 5 is disposed downstream of the cooling roll 18 or downstream of the laminating device 3. The cooling device 5 emits cold air C toward the support 103, thereby cooling the paste layer 102 via the support 103. Since the support 103, which is formed of a mesh-like body, is more breathable than the liner 101, it is preferable to cool the paste layer 102 by the cooling device 5 from the support 103 side rather than from the liner 101 side, since this provides higher cooling efficiency.

[0018] Next, the laminate 100 is wound up by the winding device 4 to form an intermediate roll 104. The laminate 100 of the intermediate roll 104 is cut into a predetermined size and shape while being unwound in a cutting process or cutting device downstream of the winding device 4. The laminate 100 is cooled by two cooling devices 5 in addition to the cooling rolls 17 and 18, so that the paste layer 102 is prevented from sticking to the cutting blade or the like during cutting. As a result, the cutter is prevented from stopping, and a decrease in production efficiency is suppressed. Furthermore, the viscosity of the paste increases due to cooling, so that excessive penetration of the paste into the support 103 composed of a mesh body is prevented. As a result, it is possible to control the thickness of the paste layer 102, and therefore the thickness of the patch as a product, to an appropriate thickness.

[0019] The patch manufacturing apparatus 1 has an air-cooled cooling device 5, so that the paste layer 102 can be cooled more reliably than the cooling rolls 17 and 18. That is, the cooling rolls 17 and 18 are configured to be kept at a low temperature themselves and to cool the paste layer 102 by physical contact with the laminate 100. However, since the cooling rolls 17 and 18 originally function as conveying rolls, the contact area with the laminate 100 is not large. Furthermore, when the conveying speed of the laminate 100 is high (e.g., 80 m / min), the contact time is also short. Therefore, there is a limit to cooling the paste layer 102 by the cooling rolls 17 and 18 alone. With the air-cooled cooling device 5, the temperature of the cold air, the range, angle, strength, etc. of the cold air emitted can be freely set according to the conveying direction and conveying speed of the laminate 100. Therefore, the laminate 100 can be exposed to the cold air C over a wider range and for a longer period of time, and the paste layer 102 can be cooled to a desired temperature. The desired temperature of the paste layer 102 is determined by, for example, the viscosity of the paste layer so that it does not stick to a cutting blade or the like in a downstream cutting process or cutting device.

[0020] The patch manufacturing apparatus 1 has two cooling devices 5 between the spreading device 2 and the winding device, but may have one or three or more. Only one of the two cooling devices 5 of the patch manufacturing apparatus 1 may be provided. In this case, as described above, since it is more effective to cool the paste layer 102 immediately after it is formed, it is more preferable that the cooling device 5 is disposed between the spreading device 2 and the laminating device 3. One more cooling device 5 may be added downstream of the laminating device 3.

[0021] In the patch manufacturing apparatus 1, the liner 101 is transported first, and the paste layer 102 is formed on the liner 101, but the support 103 may be transported first. In this case, the liner 101 is placed on the paste layer 102 formed on the support 103 in the lamination device 3.

[0022] In short, there is provided an apparatus for manufacturing a patch, which comprises a spreading device 2 that supplies a paste onto one of a series of supports 103 or liners 101 to form a paste layer 102, a laminating device 3 that places the other of the supports 103 or liners 101 on the paste layer 102 to form a laminate 100, and a winding device 4 that winds up the laminate 100 to form a roll-shaped intermediate roll 104, and which further comprises a cooling device 5 between the spreading device 2 and the winding device 4 for air-cooling the paste layer 102.

[0023] Also provided is a method for producing a patch, which includes a spreading step of supplying a paste onto one of a series of supports 103 or liners 101 to form a paste layer 102, a lamination step of placing the other of the support 103 or liners 101 on the paste layer 102 to form a laminate 100, and a winding step of winding up the laminate 100 to form a roll-shaped intermediate roll 104, and further includes a cooling step of air-cooling the paste layer 102 between the spreading step and the winding step. The cooling step may be performed between the spreading step and the lamination step, or the cooling step may be performed between the lamination step and the winding step.

[0024] According to the above-described patch manufacturing apparatus 1 and patch manufacturing method, it is possible to provide a patch manufacturing method and manufacturing apparatus capable of appropriately cooling the adhesive layer supplied onto a support or a liner. [Explanation of symbols]

[0025] 1 Patch manufacturing equipment 2 Spreading device 3. Stacking device 4 Winding device 5 Cooling device 10 Plasma supply section 11 Backup Role 12 Transport roll 13 Heating roll 14 Payout roll 15 Payout roll 16 Nip Roll 17 Cooling roll 18 Cooling roll 20 Thickness sensor 21 Ventilation system 100 Laminate 101 Liner 102 Plasma layer 103 Support 104 Intermediate roll

Claims

1. a spreading step of supplying a paste onto a series of liners to form a paste layer; a lamination step in which a support composed of a series of mesh bodies is placed on the paste layer to form a laminate; and a winding step of winding the laminate to form a roll of an intermediate body, The method further includes a cooling step of air-cooling the paste layer between the spreading step and the winding step, the cooling step is carried out between the lamination step and the winding step, A method for producing a patch, wherein the cooling step cools the paste layer from the support side rather than from the liner side.

2. The method for producing a patch according to claim 1 , wherein the cooling step is carried out between the spreading step and the laminating step.

3. a spreading device for supplying a paste onto a series of liners to form a paste layer; a lamination device for forming a laminate by placing a support composed of a series of mesh bodies on the paste layer; a winding device for winding the laminate to form a roll of an intermediate body, A cooling device for cooling the paste layer by air is further provided between the spreading device and the winding device, the cooling device is disposed between the stacking device and the winding device; 2. The apparatus for producing a patch, wherein the cooling device cools the paste layer from the support side rather than from the liner side.

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