Piezoelectric device for targeted diffusion of active substances in animals

Abstract

The present invention relates to a refillable device (1) for spraying an active substance, comprising a reservoir (2) containing at least one active substance, the device being equipped with a piezoelectric spray mechanism (6). The device is attached to or mounted within an animal's collar. The invention also relates to the use of the device for spraying an active substance in a desired direction, from a distance, and in a controlled manner. The device can be used in multiple directions, independent of the animal's movement.

Description

Technical Field

[0001] The present invention relates to the field of diffusion devices, and more specifically to the field of ultrasonic nebulizer-type aerosol diffusion devices in which vibrations at high oscillation frequencies enable the diffusion of particles. More specifically, the present invention relates to a device equipped with a piezoelectric diffusion system that can be carried by an animal's collar and operate in a multi-directional manner even when the animal being treated moves.

[0002] Many active substance diffusion devices exist on the market. Most of these devices are "passive" devices that only require the movement of ambient air to disperse the liquid into the surrounding environment. Other devices are powered by a battery or via a power outlet. However, in the latter case, a power supply by cable is required, and thus it is only intended for use in the home or at most in the passenger compartment of a vehicle.

[0003] Other diffusion devices use ultrasonic transducers to spray a liquid solution of the active substance into the air. However, currently, there is no piezoelectric device that can be attached to an animal's collar and treat the animal as well as possible with an active substance, especially a repellent, a sedative, an antibacterial agent, or a disinfectant, even when the animal moves.

[0004] The state of the art refers in particular to diffusion devices operating by heating for use with a wall outlet. The latter has the disadvantage of changing the most temperature-sensitive active substances, especially in the case of essential oils. To lower the operating temperature with a wall outlet, it is known to formulate the active substance using a solvent, especially including a very volatile naphtha type. As a result, on the one hand, the treatment agent is diluted, and on the other hand, the organic solvent is released, potentially making the environment toxic and flammable, which is undesirable.

[0005] In animal devices, repellent treatment is most often carried out, for example, by using a polymeric matrix designed to release a substance having this effect, or further by applying a formulation for spot-on pipettes, such as a shampoo or lotion for pest control purposes. The concentration of the active substance in the polymeric matrix tends to decrease over time, and thus the dosage and distribution of the active substance are non-linear throughout the period of use. For antibacterial agents, disinfectants, or so-called calming active substances, in most cases, they are intended for thermal diffusers that vaporize the active substance into the surrounding air, and are thus well-suited for animals in apartments. However, in the context of the application of repellents and / or calming active substances, there is no practical solution that enables the combination of the spraying characteristics of the solution of the active substance with the aspects of targeted and localized treatment that are the existing applications.

[0006] Among the localized solutions are pneumatic aerosol devices, but these are not necessarily the most suitable. This is because the active substance is released via a propellant that can be flammable or even toxic at high dosages. In the case of polymeric matrices, another drawback is the fact that the amount of the active substance being diffused does not remain constant over the period of use of the aerosol device. In fact, as the number of uses increases, the propellant gas decreases, resulting in a gradual decrease in the release of the active ingredient. Furthermore, pneumatic aerosol devices require dilution of the incorporated active substance, thus limiting the concentration that can be used and therefore the effectiveness.

[0007] Among diffusers worn by animals, patents US4627385, US8714113, and US5927233 are sometimes mentioned, which disclose casings, especially intended to be attached to collars to deter a dog's barking. To do this, the diffuser can deliver an olfactory signal obtained by spraying the essential oil of lemongrass stored in a reservoir incorporated in the casing, or an electric shock through an electrode, or an audio signal, in response to the barking sound. The reservoir is fitted with an electromagnetic valve whose opening is electronically controlled. These patents do not disclose or suggest the attachment of a piezoelectric system to a collar for use in treating parasites or other pests.

[0008] Regarding devices applied to animals, a therapeutic inhaler for cows is known from WO1993 / 013730A1. This type of inhaler comprises a piezoelectric diffusion system coupled to a breathing mask designed to spray a therapeutic substance in order to convey the therapeutic substance through a pipe connecting the mask and the device. It is an aerosol therapy used when a life-threatening acute illness occurs in the corresponding animal, making it possible to avoid the diffusion of the therapeutic substance into the surrounding air. This system is intended for use in animals with breathing difficulties and thus does not move during a single treatment. This document does not disclose at all a piezoelectric device attached to a collar for use on an on-demand and mobile animal. More generally, in the prior art, aerosol therapy treatments are poorly tolerated by animals that have to have a restraint mask applied. There are no prior art proposals for improving aerosol therapy devices for animals.

[0009] Application EP0897755A2 discloses an invention related to a piezoelectric liquid spray device and a method for repelling or eliminating harmful organisms. This patent discloses a method of killing and repelling insects by releasing atomized pesticide particles into the air. The liquid is atomized by vibrations caused by an electrical signal and does not require a pressurized gas tank. This method makes it possible to reduce the size of the system. The size of the atomized particles is less than 20 μm. The amount of the atomized active substance is 0.01 - 20 mg / h / m3. This document discloses a method for repelling and eliminating harmful insects by spraying at least one active substance. The active substance can be used alone or in a mixture and is in a chemically active form. This application does not disclose an ultrasonic device attached to a collar of a moving animal, or a treatment based on pheromones or essential oils.

[0010] Document EP2797411B1 discloses an ultrasonic atomization device comprising a reservoir of a solution containing a substance for pest control selected from the methofluthrin group. However, this document does not specifically disclose the use of a piezoelectric device attached to a collar, nor does it disclose a calming treatment.

[0011] Alternatively, patent US9185884B2 discloses an animal control collar. This collar is equipped with a fragrance diffuser. However, this patent does not mention any piezoelectric device and does not mention any diffusion of the active substance.

[0012] Patent US8741965 discloses a method for modifying the behavior of an animal aimed at calming the animal, especially when it is stressed. For this purpose, the present invention consists in using a calming pheromone in the form of a sprayed solution or in the form of an active substance integrated into a polymer matrix designed to be worn by the animal. However, this document does not mention a piezoelectric device attached to a collar for diffusing the active substance.

[0013] Considering the prior art, there is a need to provide a piezoelectric device that is installed around the neck of an animal and is suitable for better targeting the area to be treated, as well as enabling localized treatment and / or treatment in a given direction.

[0014] Furthermore, there is also a need to provide a device that can operate in a multi-directional manner regardless of the positioning of the device and enable operation even on a moving animal. Multi-directional means that, regardless of the orientation of the device and the movement it undergoes, it is understood to mean a device that can effectively spray the active substance.

[0015] Therefore, in order to achieve the above object, it is necessary to lightweight, miniaturize, and improve the active substance spraying system.

[0016] The device according to the present invention proposes to meet these different needs.

[0017] Another advantage of the present invention with respect to other diffusion systems is based on the use of a piezoelectric device that enables the dispensing of potentially dangerous solvents and flammable propellants.

[0018] Furthermore, the piezoelectric device according to the present invention presents the possibility of using either a pure active substance or a diluted active substance, and thus presents the possibility of being used in a wider range of active substance concentration ranges than state-of-the-art pneumatic devices. Therefore, it is easier to propose a range of values that match the desired effectiveness. Therefore, the repellent active substance can be used purely or, if necessary, highly concentrated in solution. Similarly, the sedative active substance can be used in a very diluted state without changing the spray. Furthermore, the piezoelectric system according to the present invention presents the advantage of stabilizing the concentration of the active substance over time and regardless of the number of uses.

[0019] The piezoelectric diffusion system of the present invention also makes it possible to limit the loss of active substances, such as essential oils, which are particularly vulnerable due to their sensitivity to heat. In fact, since the device does not generate heat during operation, it is preferable for heat-sensitive active substances.

[0020] Currently known spray treatment means do not allow for an accurate and controlled dosage of the active substance. In terms of treating animals, it can be demonstrated that there is a need to benefit from a device that allows for an accurate adjustment of the dosage administered while the animal is moving and in a localized manner. This is what the piezoelectric system according to the present invention enables.

[0021] The present invention makes it possible to achieve the above-mentioned objectives and overcome the drawbacks of state-of-the-art devices.

[0022] When an animal runs or walks, conventional systems including a piezoelectric system do not allow the device to operate in any direction imposed by the movement of the animal while it is moving. Furthermore, conventional diffusion systems do not offer the possibility of diffusing in a targeted and localized manner towards a specific zone to be treated or another zone. However, it is useful to be able to permanently attach to the animal a device that can be activated when needed.

[0023] In the case of a restless or excited animal, it can be demonstrated that it is necessary to quickly calm it by diffusing an appropriate active substance. In such cases, it is important to be able to target the otorhinolaryngology (ENT) area.

[0024] Alternatively, when an animal is suffering from itching and, for example, scratching its own chest, it is wiser to spray an anti-itch agent, a repellent, or even an insecticide spray onto the animal's body in order to relieve or treat it. Therefore, it is necessary to have a portable device that presents modular functions for spraying, flow orientation, and mobility of such a device.

[0025] The object of the present application is to propose a novel piezoelectric device in animals and a novel use of this device.

[0026] An animal is understood to mean any animal that can wear a device as described in the present invention. Preferably, an animal is understood to mean a domestic animal such as a cat, dog, or horse.

[0027] The object of the present invention is to provide a piezoelectric device and the use thereof for the diffusion of an active substance, particularly a pest repellent, a sedative, or an analgesic, placed near the neck of an animal and capable of effectively reaching the desired area of the body to be treated. For example, in the case of a pest repellent product, the desired area can particularly be the abdomen, chest, legs, and flanks. In fact, for example, it is known that the path of entry of mites to reach the lower part of a pet's body is the legs. For the diffusion of a sedative or an anti-stress active substance, it is preferably to diffuse towards the ENT area to enable inhalation of the active substance. For the distribution of an analgesic active substance, the device can be directed towards any zone of the body to be treated, for example, towards the back.

[0028] Another object is to provide an automated device designed to enable the generation of clouds or fog towards the area of interest of the animal's body or to diffuse particles containing an active substance of a size suitable for inhalation.

[0029] It is clear that the implementation of the device according to the present invention takes into account the technical constraints related to miniaturization, the stability of the active substance in the liquid, as well as its effectiveness against the target, and its practicality for both the animal and its owner. In fact, the wearing of the device must not be obstructive or encourage the animal to remove it.

[0030] Accordingly, an object of the present invention is a refillable spray device comprising a reservoir containing at least one active substance, the device being characterized in that it enables the active substance to be sprayed in a controlled and remote manner and in that it is equipped with a piezoelectric spraying mechanism, and in that the device is attached to an animal's collar.

[0031] The present invention also relates to the use of such a device, characterized in that it is attached to an animal's collar and can be used in a multi-directional manner independently of the movement of the animal. Being able to be used in multiple directions means that, regardless of the movement or position of the animal, and thus regardless of the movement or position of the device being worn, the piezoelectric system can be activated for the diffusion of the active substance. Whether the animal is standing, lying down, stationary or moving, the device according to the present invention maintains its function and enables the effective diffusion of the active substance regardless of whether it is positioned horizontally, vertically or "upside down".

[0032] A refillable device is understood to mean that the device can be refilled after use when the reservoir is empty by means known to those skilled in the art. Thus, the reservoir can be included in the form of a replaceable cartridge or can be provided with a filling valve integrated directly into the surface of the reservoir.

[0033] The device according to the present invention consists of an atomization body (1) and a reservoir (2), as shown in FIG. 1. The atomization body comprises a casing containing a sealing system, a piezoelectric system, an electronic board and a battery for powering the system. In a particular embodiment, the atomization body may be equipped with an orientation mechanism for the piezoelectric system, which enables spraying in a defined direction. In the remainder of the present application, the reservoir of the device according to the present invention will be defined as either a reservoir or a "cartridge", which may be, interchangeably, a refillable and reusable cartridge or a disposable cartridge.

[0034] In a preferred embodiment, the reservoir (2) is a cartridge (3) comprising a wick (4) of a length selected according to the size of the reservoir, which is immersed and which resembles a substantially cylindrical cartridge. This wick is inserted longitudinally into the cylindrical cartridge, which has a dispensing opening at one of its ends and a bottom at the other. The dispensing opening has a diameter smaller than the diameter of the cylinder and is provided to accommodate the wick. Thus, the wick fills the space at the outlet of the cartridge and protrudes from the outlet. The adequacy between the diameter of the wick and the diameter of the opening of the reservoir advantageously avoids inappropriate and undesirable outflows caused by movement constraints and thus makes it possible to ensure a first seal between the wick and the dispensing opening.

[0035] Preferably, the wick is flexible and is made of woven fibres of a cellulose type or derivative, treated to be water-repellent or not. In another embodiment, the wick may be rigid and made of a porous material of the ceramic or plastic type. A person skilled in the art will adapt the nature of the wick to the nature of the active substance to be delivered.

[0036] In the device according to the invention, the wick is of cylindrical shape and, as shown in FIG. 2, its ends have flat surfaces. The piezoelectric pad is then in contact with the entire flat surface of the wick. In this embodiment, the emission of the mist is in a single direction perpendicular to the surface of the wick.

[0037] In an alternative embodiment, the surface of the core in contact with the piezoelectric pad has a rounded shape, a pointed arch or preferably a hemispherical shape. In this variant, the device according to the invention has the advantage of allowing the on-demand orientation of the piezoelectric pad in contact with the core. Furthermore, this shape maintains a well-proportioned contact with the center of the perforated membrane located on the piezoelectric pad, regardless of the orientation of the piezoelectric pad. This makes it possible to supply a sufficient and constant amount of liquid to the piezoelectric cell while reducing the tension of the pad, which is a fragile component of the system. Thanks to this variant, the device makes it possible to correct the orientation of the piezoelectric pad and thus to define a specific direction selected for spraying according to the display (Figure 5).

[0038] In a particular embodiment, the orientation mechanism of this embodiment comprises a ball-and-socket type mechanism (7) for enabling pivoting about the vertical axis of the atomization body (1) of the piezoelectric system. This mechanism not only makes it possible to direct the spray more accurately towards a targeted area, but also makes it possible to ensure that there is no risk of the liquid contained in the reservoir (2) of the device spilling accidentally during movement, and also contributes to strengthening the seal of the system. By using such a ball-and-socket in the orientation mechanism, it is also possible to simplify the miniaturization of the device by making it a more suitable device for use on compact and mobile animals.

[0039] The orientation mechanism (7) of the piezoelectric pad is based on a ball-and-socket type connection between two separate parts. Thus, the orientation mechanism (7) of the piezoelectric pad comprises a spherical or hemispherical movable part (8') that supports the piezoelectric pad and its specific seal, but the movable part forms a frame in which it is embedded and also comprises a preferably hemispherical fixed part (8) that enables the movable part to rotate in order to direct the spray at the outlet of the device.

[0040] The treatment angle and direction are defined by the mechanism and depend on the intended use. The maximum orientation angle of the pad (6) by the orientation system (7) is 45 degrees with respect to the axis of the core (4 or 4’) in all directions. Therefore, in order to ensure a permanent and optimal contact between the core (4 or 4’) and the piezoelectric pad (6), the inclination of the pad on the core is limited to 45°.

[0041] This mechanism can be enhanced by locking the angle, either by adding a notch mechanism or by applying a specific treatment to the contacting surfaces to control the roughness.

[0042] In embodiments where the core of the device remains vertical, the orientation mechanism (7) of the piezoelectric pad (6) advantageously enables the spray to be directed in a selected direction without tilting the device, thus maintaining an optimal impregnation of the core (4 or 4’) to ensure the continuity of the liquid supply until the liquid is completely consumed, even in the case of a partially empty or inclined reservoir. This problem is frequently encountered in spray devices equipped with dip tubes. The dip tube can no longer spray when the reservoir is empty or when it is tilted. Therefore, the present invention overcomes the drawbacks due to dead volume or the volume accessible to the dip tube.

[0043] According to a preferred embodiment, the seal between the reservoir (2) and the atomization body (1) is ensured by a joining system (5) that is particularly suitable for the device according to the invention. The seal is preferably in the form of an O-ring in an elastic material selected from materials such as acrylonitrile-butadiene rubber, fluorinated rubber, fluorosilicone rubber, polyacrylate, ethylene acrylate rubber, perfluorinated rubber, silicone, EPDM, fluorinated ethylene propylene copolymer, polytetrafluoroethylene, or polyurethane. The seal is selected from those having a hardness of 50 to 100 Shore A, enabling both easy reservoir replacement and good mechanical strength for replenishment after insertion. This seal system is arranged in a groove specially adapted to ensure the tightness and optimal positioning of the refill cartridge while mechanical stress induced during refilling of the device is applied or during the movement of the animal.

[0044] Within the scope of the intention of the present invention, the reservoir or cartridge can be made of known materials that have been conventionally used, such as glass, plastic, or any other material that a person skilled in the art deems suitable for the present invention.

[0045] It is understood that the cartridge will be filled with the active substance before the core is inserted. Then, after the active substance rises through the core according to capillary action, it can diffuse from the cartridge towards the dispensing opening.

[0046] Advantageously, contacting the active substance with the piezoelectric element (6) will occur when the active substance is transported to its end along the core by capillary action. Then, the active substance can be sprayed in the form of a cloud of particles. Within the scope of the intention of the present invention, it is understood that the particles are droplets of a liquid solution.

[0047] Unlike pressurized pneumatic systems, the piezoelectric system according to the present invention allows for a certain modularity with respect to the concentration of the active substance that can be used. In fact, the device of the present invention surprisingly enables the use of a very concentrated composition of the active substance, or even of the pure active substance, thus without using a solvent, and therefore increases the efficiency when using a dose-dependent active substance.

[0048] In a specific embodiment according to the present invention, the active substance is a substance formulated in a liquid composition so as to be able to come into contact with the piezoelectric device, and its vibration frequency enables the liquid to be atomized and the substance to be dispersed as a cloud or mist.

[0049] According to the present invention, the liquid composition containing the active substance is of an aqueous, alcoholic, aqueous-alcoholic, or oily type, or in the form of an emulsion whose properties are compatible with the active substance. According to a specific embodiment, the composition consists only of the pure active substance without a solvent. According to another embodiment, the active substance is diluted in the composition by at least one solvent.

[0050] In a known manner, the active substance is formulated in a suitable solvent. Examples of solvents that can be used specifically include aromatic or aliphatic hydrocarbons, halogenated hydrocarbons, aromatic or aliphatic alcohols, esters, ethers and ketones, or water. More preferably, the solvents that can be used are triglycerides such as vegetable oils or animal oils, or alcohol solvents such as ethanol.

[0051] For example, formulation adjuvants well known in the art such as stabilizers, surfactants, synergists, or antibacterial agents may also be added.

[0052] In a preferred variant, the active substance according to the present invention represents 0.01% to 100% of the liquid composition, preferably 0.1% to 50%, and even more preferably 0.5% to 30%.

[0053] According to one embodiment, the active substance is selected from an insecticide, a repellent, a fragrance, an anti-stress agent, an energizer, a cosmetic hair care agent, an antipruritic agent, an active substance for the treatment of respiratory diseases, an analgesic, or a mixture thereof.

[0054] The insecticides and repellents of the present invention are those conventionally used in the fight against the aforementioned harmful organisms and are known to those skilled in the art. For example, the insecticides and repellents are specifically selected from the group consisting of pyrethroids, pyrethrins and their derivatives, carbamates, formamidines, carboxylic acid esters, N,N-diethyl-3-methylbenzamide (DEET), ikaridin, phenylpyrazoles, organophosphorus compounds, organohalogen compounds, neonicotinoids, avermectins and their derivatives, spinosyns, essential oils and their components, such as terpenes and their derivatives (alcohols, esters, aldehydes), and sesquiterpenes and their derivatives (alcohols, esters, aldehydes).

[0055] In a variant of the preferred embodiment, the active substance is a repellent or insecticide selected from essential oils such as ravandine essential oil, lemon eucalyptus essential oil, lemongrass, lavender, neem, peppermint, spearmint, pennyroyal, wintergreen, or basil, or a mixture thereof.

[0056] According to a variant of the present invention, the repellent is selected from components of essential oils such as geraniol, limonene, menthol, α-pinene, linalool, citriodiol, citronellal, or a mixture thereof.

[0057] The fragrance can be of natural or synthetic origin and is selected from perfumes, aromas, essential oils, and their components.

[0058] The anti-stress agent or sedative can specifically be a vegetable oil such as cannabis oil rich in cannabinoids, or an essential oil such as valerian, dog fennel, pine, tangerine, bitter orange, vervain, ravintsara, chamomile, lavender, marjoram, ylang-ylang, rosemary, eucalyptus, or mint, or a pheromone or a mixture thereof.

[0059] The anti-itch agent can be an essential oil, an aliphatic alcohol, an ester, a fatty acid and its ester, a vitamin, or a mixture thereof.

[0060] The cosmetic hair care agent can be a fatty substance such as alcohol, ester, vegetable oil, glyceride, acid, ceramide, or vitamin.

[0061] The active substance for treating respiratory diseases is understood to mean any active substance that can treat respiratory conditions of the airways or nasal cavity of animals, such as asthma or chronic bronchitis. The active substance can be selected from corticosteroids, bronchodilators, bronchoconstrictors, antihistamines, or any other treatment suitable for the condition.

[0062] The analgesic can be an essential oil, a monoterpene alcohol, a monoterpene aldehyde, a monoterpene ester, or a mixture thereof, preferably not containing THC, specifically a cannabinoid derivative derived from cannabis oil. Particularly preferred is the use of methyl salicylate, menthol, wintergreen essential oil, juniper, peppermint, lemon eucalyptus, or cannabis oil.

[0063] The antibacterial agent and / or disinfectant can be an essential oil, a monoterpene alcohol, a monoterpene aldehyde, a monoterpene ester, or a hydroalcoholic derivative, or a mixture thereof. In particular, ravintsara, grapefruit essential oil, lemon, tea tree, marjoram, Eucalyptus radiata, ravintsara, or a mixture thereof will be preferred.

[0064] In the context of the present invention, the above-mentioned active substances may be used alone or in combination, depending on the intended purpose.

[0065] As described above, the device according to the present invention also comprises a piezoelectric element well-known to those skilled in the art. By way of example, the device particularly comprises a piezoelectric ceramic pad which is brought into contact with the solution in order to spray it via a core. The piezoelectric pad is covered with a perforated membrane, the perforation size of which may vary from 1 to 40 μm, preferably from 3 to 20 μm. When operating, the pad vibrates at a frequency of 75 to 190 kHz. According to the present invention, it is possible to target a specific size of the particles to be sprayed by varying the size of the perforations and the frequency of vibration.

[0066] According to the present invention, the liquid composition is sprayed in the form of particles having an average diameter of 1 μm to 40 μm. The size of the particles is adapted to the intended use. The size of the spray particles is modulated, on the one hand, by the vibration oscillation frequency of the piezoelectric pad of the device and, on the other hand, depends on the size of the micro-perforations of the membrane of the piezoelectric device.

[0067] According to a particular embodiment, in the case of the diffusion of the active substance against pests, the composition of the active substance will preferably be sprayed with a particle size of 10 to 40 μm, more preferably 20 to 40 μm.

[0068] In a preferred embodiment, when the active substance is a liquid solution of a sedative, an analgesic or an active substance for the treatment of respiratory diseases, it is appropriate to target the otorhinolaryngology region in a privileged manner. In order to reach the target organ and allow inhalation of the active substance, it is preferably necessary to spray towards the animal's snout or olfactory system. Thus, it is appropriate that the diameter of the droplets is suitable for spraying the sedative active solution for inhalation. The droplets produced by the device according to the present invention have a diameter of 1 μm to 20 μm, preferably 1 to 10 μm, in order to allow optimal inhalation.

[0069] Within the scope of the intention of the present application, the pure active substance or the formulation containing the active substance must be integrated into the reservoir of the device as described above. The device must be able to be used in any direction with respect to the moving animal. Therefore, the device should be attached to the animal by a harness or a collar, preferably a collar, and the device should be removable.

[0070] The fastening means of the device according to the invention is selected from a self-gripping tape, a lace or an adhesive system, a push-button system, a notching system, or any other fastening means well-known to those skilled in the art.

[0071] In a particularly advantageous embodiment, the fastening means can be capable of modifying the orientation and the spray according to the desired effect. For this purpose, the device according to the invention is also provided so as to be able to benefit from a rotary or adjustable mounting system attached to the collar. In such a specific embodiment, the fastening means is mounted on a rotary fastener fastened to the collar. The piezoelectric device will be attached to a rotary support capable of ensuring a 360-degree distribution of the active substance. In a specific embodiment involving a spray of a repellent or insecticide active substance, the spray is preferably directed towards the chest, the flanks, and / or the lower part of the animal's body. In the case of a sedative and / or an analgesic, the spray will preferably be directed towards the ENT region for inhalation.

[0072] Therefore, according to the present invention, the use of the device presents the advantage of generating a spray in different selected directions. On the one hand, the device according to the invention enables operation in any direction and, in particular, can be oriented according to the zone reached through its fastening means on the collar. On the other hand, the use of a core having a hemispherical end within the device makes it possible to orient the piezoelectric pads in contact with the core in a given direction.

[0073] According to the present invention, the piezoelectric spray mechanism of the device includes an electronic substrate. The electronic substrate enables the operation of the piezoelectric system. According to a particular embodiment, the operation may be performed by directly and manually pressing a button on the device. In a preferred embodiment, the electronic substrate enables remotely controlling and / or triggering the spray. In a particular embodiment, the triggering is executed by programming, and the programming can define the day and / or time and / or the spraying time. In another variant, the triggering is executed on demand through remote control. Those skilled in the art will adapt an appropriate remote operation system to the device according to the present invention.

[0074] Accordingly, the present invention relates to a refillable device for spraying an active substance, comprising a wick, a removable reservoir containing at least one active substance, an atomizing body containing a piezoelectric spray mechanism, and a seal for ensuring tightness between the reservoir and the atomizing body, characterized in that the device is attached to an animal collar or is attached within the collar.

[0075] The present invention relates to the device, characterized in that the device can be oriented in a plurality of directions.

[0076] The device according to the present invention is characterized in that the piezoelectric spray mechanism comprises a piezoelectric pad in contact with the active substance, and the pad is covered with a perforated membrane vibrating at a frequency of 75 to 190 kHz and having perforations with a size of 1 to 40 μm.

[0077] The device according to the present invention is characterized in that the piezoelectric pad is in contact with a wick having a flat or hemispherical end.

[0078] The device according to the present invention is characterized in that the active substance is an insecticide, a repellent, an analgesic, or a sedative active substance and represents 0.01% to 100% by weight of the liquid composition.

[0079] The device of the present invention is characterized in that the liquid composition is sprayed in the form of particles having an average diameter of 1 μm to 40 μm.

[0080] In summary, the present invention relates to a refillable spray device comprising: (a) a removable reservoir containing at least one active substance; (b) a piezoelectric spray mechanism comprising a piezoelectric element controlled by an electronic substrate, wherein (c) the device is attached to or mounted within an animal collar. The reservoir has a dispensing opening through which the core allows the active substance to be directed towards the piezoelectric element regardless of the direction of use of the device. The tightness of the assembly is ensured by a joining system between the reservoir and the atomizing body of the device, which is selected to allow the reservoir to be filled or the refill cartridge to be replaced.

[0081] The present invention also relates to the use of a refillable device for spraying an active substance, comprising at least a reservoir containing the active substance and a piezoelectric spray mechanism, wherein the device is intended to be fastened on or within an animal collar.

[0082] The use of the device is characterized in that the device can be used in multi-directional directions regardless of the movement of the animal.

[0083] The use of the device is also characterized in that the device enables the active substance to be sprayed in a localized manner onto the target zone of the animal.

[0084] The use of the device is characterized in that the liquid composition containing the active substance is sprayed in the form of particles having an average diameter of 1 μm to 40 μm.

[0085] The use of the device is characterized in that the spray targets the otorhinolaryngeal region of the animal, or the abdomen, chest, legs, or flanks of the animal.

[0086] Accordingly, the present invention relates to the use of a device equipped with a piezoelectric spray mechanism that enables the active substance to be sprayed in a controlled and remote manner.

[0087] Figures 1 to 6 show, without limiting its shape, an example of a device according to the present invention.

Brief Description of the Drawings

[0088]

Figure 1

Figure 2

Figure 3

Figures 4 - 5

Figure 4

Figure 5

Figure 6

Figure 7

[0089] The present invention is illustrated by the following non-exhaustive and non-limiting examples.

[0090] Example 1: Diffusion device for anti-mite and anti-flea active substances for dogs A prototype of the device for the distribution of the active substance against mites and fleas was fabricated. The device consists of · A hemispherical polypropylene casing with a diameter of 4 cm and a height of 2 cm, · An alcohol solution containing lavandin essential oil representing a 5 wt% composition, encapsulated within a cylindrical polypropylene reservoir with a volume of 3 mL (diameter 3 cm, height 0.44 cm), and the reservoir is provided with an outlet orifice, · A cellulose core that serves to transfer the liquid from the reservoir to the piezoelectric pad, · A nitrile rubber O-ring to ensure a seal between the reservoir and the hemispherical casing, · A piezoelectric ceramic pad (PZT4 SMMOD10F190, Steminc) that comes into contact with the solution and enables the solution to be sprayed, and the assembly is composed of an annular piezoelectric pad (outer diameter 16 mm, height 3 mm) covered with a perforated membrane (perforation size 3 - 20 μm over an area with a diameter of 4 mm). The pad vibrates at a frequency of 110 kHz, · An electronic control board that enables manual actuation of the piezoelectric pad using a push button located at the center of the hemisphere of the casing to operate the spray, · A 3.7V, 300mAh, 1.11Wh battery (29×19×5mm) powers the device. · The filling orifice is located on the casing and is fitted with a flexible silicone cap, allowing the reservoir to be filled with the active liquid. · The connector is fitted with a USB port, enabling the battery to be recharged. · The entire device described above is attached to a nylon collar equipped with a closure means in the form of a loop, such as Velcro. The device is fastened to spray the solution downward with the liquid reservoir facing upward. This device is designed to form a mist of the active substance at the outlet of the nozzle and move along the lower part of the wearer's body to protect the wearer's body from invasion by targeted parasites (mites and fleas). The electronic circuit board is programmed to enable 20 seconds of operation of the pad for a spraying volume of approximately 77 μL. The autonomy of the battery allows it to trigger approximately 100 operations before being fully recharged.

[0091] Example 2: Diffusion device for anti - mite and anti - flea active substances for dogs A prototype of the device for the distribution of repellent active substances against fleas and mites was fabricated. The device · A casing in the shape of a block with a width of 4 cm, a height of 3.5 cm, and a depth of 1.5 cm, having protrusions for housing the piezoelectric pad (see Figure 1) and grooves for housing the seal inside. · A solution based on tangerine essential oil and lemongrass essential oil (50 / 50) with repellent properties against mites and fleas, encapsulated in a cylindrical glass reservoir with a volume of 1.5 mL (diameter 1.1 cm, height 3 cm), and the reservoir is provided with an outlet orifice. It consists of an assembly comprising a piezoelectric ceramic (PZT4 SMMOD10F190, Steminc) that enables the solution to be sprayed upon contact with the solution. The annular piezoelectric pad (outer diameter 16 mm, height 3 mm) is covered with a perforated membrane (perforation size 3 - 20 μm over an area with a diameter of 4 mm). The pad vibrates at a frequency of 110 kHz, · A hydrophobicized cellulose core with a diameter of 6 mm and a height of 3.5 cm serves to transfer the essential oil mixture from the reservoir to the piezoelectric pad, · A nitrile rubber O-ring with a diameter of 11 mm ensures a seal between the reservoir and the hemispherical casing, · An electronic control card enabling manual remote operation of the piezoelectric system using remote control to activate the spray is located at the center of the hemisphere of the casing, · A 3.7V, 300 mAh, 1.11 Wh battery (29×19×5 mm) powers the device, · A USB port is attached to the connector, enabling battery recharge, · The entire device described above is attached to a nylon collar with a collar loop-type closure means. · The assembly is installed on the collar to spray the solution downward onto the animal. This device is designed and installed on the animal in an orientation such that a mist of the active substance is formed at the outlet of the nozzle and moves along the lower part of the animal, thus protecting the wearer from bites by fleas or ticks. The electronic circuit board is programmed to enable 4 seconds of operation of the pad for a spray volume of approximately 17 μL. The autonomy of the battery enables triggering approximately 500 operations before being fully recharged.

[0092] Example 3: Diffusion Device for a Sedative Active Substance for Cats A prototype of a device for the diffusion of a sedative composition for cats was fabricated. The device · A casing in the shape of a block with a width of 4 cm, a height of 3.5 cm, and a depth of 1.5 cm, having a protrusion for housing the piezoelectric pad and a groove for housing the seal therein, ·A solution (50 / 50) based on dog mint essential oil and hemp essential oil rich in cannabinoids and free of THC, having sedative and analgesic properties, diluted in ethanol up to 10% maximum, encapsulated in a cylindrical glass reservoir with a volume of 1.5 mL (diameter 1.1 cm, height 3 cm), and provided with an outlet orifice in the reservoir, ·A cellulose core having a hemispherical end, with a diameter of 6 mm and a height of 3.5 cm, which serves to transmit the essential oil mixture from the reservoir to the piezoelectric pad, ·An 11 mm nitrile rubber O-ring to ensure a seal between the reservoir and the hemispherical casing, ·Comprising an assembly equipped with a piezoelectric ceramic (PZT4 SMMOD10F190, Steminc) that comes into contact with the solution and enables the solution to be sprayed through the hemispherical core. The annular piezoelectric pad (outer diameter 16 mm, height 3 mm) is covered with a perforated membrane (perforation size 1 - 10 μm over an area with a diameter of 4 mm). The pad vibrates at a frequency of 110 kHz, ·An electronic control board enabling manual remote operation of the piezoelectric system using remote control to activate the spray is located at the center of the hemisphere of the casing, ·A 3.7 V, 300 mAh, 1.11 Wh battery (29×19×5 mm) powers the device, ·The connector is fitted with a USB port to enable recharging of the battery, ·The entire device described above is attached to an EVA collar fitted with a buckle-type closing means, ·The assembly is installed on the collar to spray the solution towards the top of the animal's head.

[0093] This device is designed and installed on an animal in an orientation such that a mist of the active substance is formed at the outlet of the nozzle and directed towards the ENT region of the cat. The electronic circuit board is programmed to enable 10 seconds of operation of the pad for a spraying volume of approximately 38 μL. The autonomy of the battery enables triggering of approximately 200 operations before being fully recharged.

Claims

Claim 1 A collar for an animal equipped with a refillable device for spraying an active substance, wherein the refillable spray device is attached to the collar or is attached within the collar, wherein the refillable spray device, a. a removable reservoir (2) containing a core and at least one active substance, b. an atomizing body (1) containing a piezoelectric spray mechanism, c. a seal (5) providing tightness between the reservoir (2) and the atomizing body (1), and is provided with, wherein the active substance is an active substance of an insecticide, a repellent, an analgesic, a sedative, an antibacterial agent, or a disinfectant, wherein the refillable spray device is configured to be used in a multi-directional manner regardless of the movement of the animal, a collar, wherein the atomizing body (1) is equipped with an orientation system (7) for the piezoelectric spray mechanism. Claim 2 The collar according to claim 1, wherein the piezoelectric spray mechanism comprises a piezoelectric pad (6) in contact with the active substance, and the piezoelectric pad (6) vibrates at a frequency of 75 to 190 kHz and is covered with a perforated membrane having a pore size of 1 to 40 μm. Claim 3 Use of a refillable device for spraying an active substance according to claim 1 or 2, characterized in that the device can be used in a multi-directional manner regardless of the movement of the animal. Claim 4 Use of a refillable device for spraying an active substance according to any one of claims 1 to 3, characterized in that the device enables the active substance to be sprayed in a localized manner onto the target zone of the animal. Claim 5 Use according to claim 3 or 4, characterized in that the device equipped with a piezoelectric spray mechanism enables the active substance to be sprayed in a controlled and remote manner.

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