Liquid medicine administration device

Abstract

[Problem] To prevent leakage of liquid medicine from a connection port from repeated attachment and detachment between a device body and a cradle. [Solution] A connection port 40 is provided with a liquid medicine introduction part 421 for introducing a liquid medicine fed from a liquid feed tube 14, and a first housing part 423 on which a liquid feed port 16 is mounted and that is movably attached to the liquid medicine introduction part 421. The first housing part 423 is moved relative to the liquid medicine introduction part 421 in a state in which the liquid feed port 16 is mounted on the first housing part 423, whereby a fluid connection is established with the liquid feed port 16.

Description

Technical Field

[0001] The present invention relates to a chemical solution administration device for administering a chemical solution to an object such as a living body.

Background Art

[0002] A treatment method for continuously administering a chemical solution into a patient's body is known. For example, as a treatment method for diabetic patients, a treatment method for continuously administering a trace amount of insulin into the body is known. In this treatment method, a portable chemical solution administration device that can be fixed to the user's body or clothing and carried around is used. By using a portable chemical solution administration device, it is possible to administer the chemical solution to the user throughout the day. As this type of chemical solution administration device, an insulin pump that administers insulin to the user is known.

[0003] As one of the above-described portable chemical solution administration devices, a syringe pump type chemical solution administration device having a syringe (reservoir) for storing a chemical solution and a pusher (pump mechanism) driven inside the syringe has been proposed. In a syringe pump type chemical solution administration device, a cannula is liquid-tightly connected to a liquid delivery pipe extending from the syringe, and this cannula is stabbed and left under the skin of the user, and the pusher is driven to administer the chemical solution stored in the syringe into the user's body.

[0004] Patent Document 1 describes a technique in which a liquid delivery needle member (liquid delivery needle) having a needle tube at the tip of the liquid delivery pipe is provided, while a rubber partition (rubber stopper) is provided at a connection port having a cannula, and the liquid delivery needle is pierced through the rubber stopper to connect the liquid delivery pipe and the cannula.

Prior Art Documents

Patent Documents

[0005]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0006] However, the technology described in Patent Document 1 had the following problems. A chemical solution administration device such as an insulin pump includes a device body and a cradle that are detachable from each other. The cradle is attached and fixed to the user's skin, and the device body is detached from this cradle. A reservoir, a drive unit for discharging the chemical solution from the reservoir, a liquid delivery pipe, and a liquid delivery needle are provided in the device body, and the above-described connection port is provided in the cradle. And when the device body is attached to the cradle, the liquid delivery needle is configured to pierce a rubber stopper.

[0007] However, during the use of the chemical solution administration device, for some reason, for example, when the user takes a bath or fills the reservoir with the chemical solution, it is necessary to remove the device body from the cradle. And it is necessary to reattach the device body to the cradle. For this reason, the attachment and detachment operation of the device body and the cradle is repeated during the use of the chemical solution administration device, and the liquid delivery needle is punctured and removed from the rubber stopper for the number of repetitions. As a result, for example, the puncture hole of the rubber stopper may expand or the rubber stopper itself may be damaged, and there is a risk that the chemical solution may leak from the connection portion between the rubber stopper and the liquid delivery needle.

[0008] At least one embodiment of the present invention has been made in view of the above circumstances, and specifically, it is an object to provide a chemical solution administration device capable of preventing leakage of the chemical solution from the connection port due to repeated attachment and detachment operations of the device body and the cradle.

Means for Solving the Problem

[0009] The chemical solution administration device according to the present embodiment includes a connection port for holding a cannula to be inserted into a living body, a cradle attached to the living body, a reservoir for storing a chemical solution, a liquid sending drive unit for sending out the chemical solution from the reservoir, a liquid sending pipe through which the chemical solution sent out from the reservoir flows, and a hollow cylindrical liquid sending port communicating with the liquid sending pipe. The device has a device body, and the liquid sending port and the connection port are detachably fluid-connected. The connection port includes a chemical solution introduction part for introducing the chemical solution sent out from the liquid sending pipe, and a first housing part to which the liquid sending port is attached and which is movably attached to the chemical solution introduction part. In a state where the liquid sending port is attached to the first housing part, the first housing part is configured to be relatively moved with respect to the chemical solution introduction part so as to be fluid-connected to the liquid sending port.

Effects of the Invention

[0010] According to at least one embodiment of the present invention, it is possible to prevent leakage of the chemical solution from the connection port due to repeated attachment and detachment operations between the device body and the cradle.

Brief Description of the Drawings

[0011]

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Figure 9

Figure 10

Mode for Carrying Out the Invention

[0012] Hereinafter, embodiments for carrying out the present invention will be described in detail with reference to the drawings. The embodiments shown here are examples for embodying the technical idea of the present invention and do not limit the present invention. Further, other embodiments, examples, operation techniques, etc. that can be considered by those skilled in the art without departing from the gist of the present invention are all included in the scope and gist of the present invention, and are included in the invention described in the claims and its equivalent scope.

[0013] Furthermore, the drawings attached to this specification may be schematically represented with appropriate changes in scale, aspect ratio, shape, etc. from the actual object for the convenience of illustration and easy understanding, but this is only an example and does not limit the interpretation of the present invention.

[0014] Also, in the following description, when ordinal numbers such as "first" and "second" are used for explanation, they are used for convenience and do not define any order unless otherwise specified.

[0015] In this specification, for convenience of explanation, XYZ coordinates are set as shown in the drawings. That is, the "Z direction" is the direction along the vertical direction, the "X direction" is a direction orthogonal to the Z direction and parallel to the horizontal plane, and the "Y direction" is another direction orthogonal to the Z direction and parallel to the horizontal plane (a direction orthogonal to the X direction). Therefore, in the chemical solution administration devices 100 and 110 according to this embodiment, the Z direction coincides with the thickness direction (vertical direction) of the device, the X direction coincides with the longitudinal direction (front-rear direction) along the axial direction of the device, and the Y direction coincides with the short-side direction (width direction) orthogonal to the longitudinal direction of the device.

[0016] The chemical solution administration devices 100 and 110 according to the present embodiment are devices for continuously administering a chemical solution into a user's body. Examples of the chemical solution to be administered using the chemical solution administration devices 100 and 110 include insulin, analgesics, anti-cancer treatment drugs, HIV (Human Immunodeficiency Virus) treatment drugs, iron chelating agents, and pulmonary hypertension treatment drugs. In the present embodiment, as an example of the chemical solution administration devices 100 and 110, a portable insulin pump for administering insulin into a user's body is assumed. The chemical solution administration devices 100 and 110, which are insulin pumps, are used by being attached to the surface of a living body. The surface of the living body is typically the surface of the user's skin. Also, the position where the chemical solution administration devices 100 and 110 are attached is, for example, the user's abdomen.

[0017] [First Embodiment] FIG. 1 is a schematic perspective view showing the appearance of the chemical solution administration device 100 according to the first embodiment, and FIG. 2 is a schematic exploded perspective view showing the main part of the overall configuration of the chemical solution administration device 100.

[0018] [Configuration] As shown in FIG. 1 or FIG. 2, generally speaking, the chemical solution administration device 100 includes a first main body portion 10 that holds a reservoir 12 in which a chemical solution is stored, etc., a second main body portion 20 that holds a liquid feeding drive portion 23 for feeding the chemical solution in the reservoir 12 into a living body, and a cradle 30 that holds a cannula 50 and is attached to the surface of a living body.

[0019] The first main body portion 10 is a disposable portion. The second main body portion 20 is a reusable portion. The first main body portion 10 and the second main body portion 20 are separable from each other and connectable to each other. Also, the cradle 30 and the device main body 101 in a state where the first main body portion 10 and the second main body portion 20 are connected are connected to constitute the chemical solution administration device 100.

[0020] [The First Main Body Portion] The first main body portion 10 includes a housing 11, a reservoir 12, an extrusion portion 13, a liquid delivery pipe 14, and a power supply portion 15. The housing 11 is formed in a substantially rectangular shape in a plan view (viewed in the Z direction). Further, the housing 11 is a substantially rectangular parallelepiped with an open upper side.

[0021] As shown in FIG. 2, the housing 11 includes a flat bottom surface portion 11a and a side wall portion 11b that rises along the entire outer peripheral edge of the bottom surface portion 11a. The bottom surface portion 11a is a plate portion that partitions the housing 11 in the Z direction. The bottom surface portion 11a is disposed opposite to the cradle 30 when the first main body portion 10 is mounted on the cradle 30. On the surface of the bottom surface portion 11a facing the second main body portion 20 (the upper surface of the bottom surface portion 11a), the reservoir 12, the extrusion portion 13, the liquid delivery pipe 14, and the power supply portion 15 are attached. The bottom surface portion 11a also functions as the bottom surface portion 101a of the device main body 101 to which the second main body portion 20 is attached to the first main body portion 10.

[0022] On the outer peripheral surface of the side wall portion 11b, a first guide portion 11e that engages with a second guide portion 31d described later is provided when the device main body 101 is mounted on the cradle 30. The first guide portion 11e and the second guide portion 31d have complementary shapes to each other and function as guide portions for guiding the alignment of the device main body 101 when mounted on the cradle 30. In the first embodiment, the first guide portion 11e is a convex portion that protrudes outward from the outer peripheral surface of the side wall portion 11b.

[0023] The housing 11 includes a first storage portion 11c surrounded by the bottom surface portion 11a and the side wall portion 11b. The first storage portion 11c is provided on the upper surface side of the bottom surface portion 11a and houses the reservoir 12, the power supply portion 15, etc. Further, when the lid body 21 of the second main body portion 20 and the housing 11 are connected, a liquid delivery drive portion 23 attached inside the lid body 21 is housed in the first storage portion 11c.

[0024] The housing 11 includes a second storage portion 11d. The second storage portion 11d is provided to be recessed in the thickness direction (Z direction) of the housing 11 toward the lower surface of the bottom surface portion 11a (the surface on the side connected to the cradle 30). The connection port 40 of the cradle 30 and the like are stored in the second storage portion 11d. The first storage portion 11c and the second storage portion 11d are partitioned by a partition wall 11f.

[0025] The reservoir 12 includes an outer cylinder 12a in which the chemical solution to be administered to the user is stored, and discharges the chemical solution in the outer cylinder 12a by a pressing operation of the extrusion portion 13. The reservoir 12 is provided with a discharge port (not shown) for the chemical solution at the tip, and one end of the liquid feed pipe 14 is connected to this discharge port. The other end of the liquid feed pipe 14 is connected to the liquid feed port 16 from the side of the first storage portion 11c of the housing 11. The reservoir 12 is provided with a gear 12b near the end. The gear 12b rotates by receiving the driving force of the liquid feed driving portion 23. The end of the rotation shaft of the gear 12b meshes with a feed screw 12c. The feed screw 12c is provided to be movable in the X direction. The reservoir 12 rotates the gear 23b and the gear 12b by the drive of the liquid feed driving portion 23, and the feed screw 12c rotates while rotating according to the rotation of the gear 12b, and moves the extrusion portion 13 in the X direction. The chemical solution in the reservoir 12 is sent to the liquid feed pipe 14 according to the pushing amount of the extrusion portion 13 that moves by the rotation of the feed screw 12c. The liquid feed pipe 14 is detachably fluid-connected (a connection state in which the chemical solution can flow) to a connection port 40 described later via the liquid feed port 16.

[0026] Note that the reservoir 12 is not limited to a syringe, and may be, for example, a soft bag or the like as long as it can store the chemical solution. The reservoir 12 only needs to be able to discharge the chemical solution by the extrusion portion 13.

[0027] The power supply unit 15 supplies the driving power necessary for driving the chemical solution administration device 100. The power supply unit 15 is composed of, for example, a battery that serves as a power source for driving the liquid feed driving portion 23 and the like, and a battery box that houses the battery. The power supply unit 15 is connected to an electrode (not shown) on the circuit board 22. Note that the power supply unit 15 may be arranged inside the lid body 21 as a component of the second main body portion 20.

[0028] As shown in FIG. 3, the liquid delivery port 16 is provided so as to protrude into the second storage portion 11d. The liquid delivery port 16 has a hollow cylindrical shape with a liquid delivery hole 16a formed at its tip. The base end of the liquid delivery port 16 is connected to the liquid delivery pipe 14, and the tip is attached to a connection port 40 provided on the cradle 30. The liquid delivery hole 16a is formed so as to penetrate the liquid delivery port 16 along the central axis of the liquid delivery port 16. The opening end face of the liquid delivery hole 16a may have, for example, radially (in other words, cross-shaped) grooves centered on the liquid delivery hole 16a.

[0029] 〈Second main body portion〉 The second main body portion 20 has a lid body 21, a circuit board 22, and a liquid delivery drive portion 23, and is attached to the first main body portion 10. The second main body portion 20 is a portion where the electronic control functions of the chemical solution administration device 100 are intensively arranged. The second main body portion 20 is configured by housing electronic control function components such as the circuit board 22 and the liquid delivery drive portion 23 inside the lid body 21.

[0030] The lid body 21 is configured to be detachable from the housing 11 of the first main body portion 10. The upper surface of the lid body 21 forms the top surface of the chemical solution administration device 100. Electronic control function components such as the circuit board 22 and the liquid delivery drive portion 23 are attached to the lower surface side of the lid body 21.

[0031] The liquid delivery drive portion 23 includes a motor 23a and a gear 23b. The motor 23a is a drive source for moving the extrusion portion 13 in a predetermined direction to send out the chemical solution in the reservoir 12. The gear 23b is composed of a plurality of stages of gears, and the gear at the final stage meshes with the gear 12b. Thereby, the driving force (rotational force) of the motor 23a is transmitted to the gear 12b via the gear 23b.

[0032] Further, the second main body 20 includes a liquid feed amount detection unit 24 capable of detecting the liquid feed amount of the chemical solution based on the rotation speed of a motor 23a such as an encoder, a communication unit 25 which is an interface for enabling communication with the outside, and a control unit 26 constituted by a known microcomputer including a CPU, a ROM, a RAM, etc. The communication unit 25 and the liquid feed drive unit 23 operate based on a predetermined program under the control of the control unit 26.

[0033] 〈Cradle〉 The cradle 30 has a holder case 31 and a connection port 40. The holder case 31 includes a placement surface portion 31a and side wall portions 31b. The connection port 40 is attached to the upper surface (placement surface portion 31a) of the holder case 31. The apparatus main body 101 is temporarily attached to the cradle 30 in a state of approaching diagonally upward (see FIG. 7), and then is completely attached to the cradle 30 by moving downward around the connection port 40.

[0034] The holder case 31 is provided with an adhesive portion 31c on its lower surface. The adhesive portion 31c has a part that protrudes outward more greatly than the placement surface portion 31a, and is a portion for attaching the cradle 30 to the living body surface (the skin of the user). The placement surface portion 31a is formed in a substantially rectangular shape in plan view.

[0035] When the first main body 10 is mounted on the cradle 30, the bottom surface portion 101a (the bottom surface portion 11a of the first main body 10) of the apparatus main body 101 is placed on the placement surface portion 31a. The side wall portions 31b are formed to stand up in the thickness direction (Z direction) of the cradle 30 from three sides of the placement surface portion 31a, and no side wall portion 31b is formed on the remaining one side of the placement surface portion 31a. Note that the side wall portions 31b may be provided so as to surround the placement surface portion 31a along the outer peripheral edge on all four sides.

[0036] The cradle 30 is provided with a second guide portion 31d for guiding the alignment when the device main body 101 is mounted. The second guide portion 31d has a shape complementary to that of the first guide portion 11e and engages therewith. In the first embodiment, the second guide portion 31d is provided on the inner surface of the side wall portion 31b in the vicinity of the connection port 40, extends along a substantially vertical direction (X direction) from the proximal end side with respect to the side wall portion 31b, and is provided as a concave groove that bends obliquely upward along the detachment direction D2 of the device main body 101 from the middle. That is, the second guide portion 31d has a shape along the mounting locus when the device main body 101 is mounted on the cradle 30. When the device main body 101 is mounted, the second guide portion 31d engages with the first guide portion 11e provided on the outer peripheral surface of the side wall portion 11b of the first main body portion 10 and guides the moving direction of the first guide portion 11e.

[0037] 〈Connection Port〉 As shown in FIG. 4 or FIG. 5, the connection port 40 is provided on the upper surface of the mounting surface portion 31a of the cradle 30. The connection port 40 includes a first connection portion 42 and a second connection portion 43 in the port main body 41. The connection port 40 is a port connected to the liquid supply pipe 14 via the first connection portion 42.

[0038] The first connection portion 42 is disposed on the side wall of the port main body 41 facing the liquid supply port 16, and functions as an introduction port for introducing the chemical solution sent out through the liquid supply port 16 into the connection port 40 when the first main body portion 10 is mounted on the cradle 30. The second connection portion 43 is disposed above the connection port 40 and is punctured by a known puncture tool (not shown) when the cannula 50 is indwelled in the living body. The second connection portion 43 functions as a puncture port for removing only the puncture needle after the cannula 50 is indwelled.

[0039] Below the port body 41 of the connection port 40, a holding portion 44 is provided for holding the proximal side of the cannula 50 that is indwelled in a living body and delivers a chemical solution into the living body. The cannula 50 protrudes from the holding portion 44 toward the user's body, and at least the tip portion is indwelled in the living body. The cannula 50 is made of a resin material such as polyurethane, nylon, ethylene-tetrafluoroethylene copolymer (ETFE), etc. Note that the puncture device is removed from the cradle 30 and discarded after inserting the cannula 50 into the interior of the living body.

[0040] The holding portion 44 is formed in a funnel shape for guiding the chemical solution that has flowed in from the communication passage 421a of the chemical solution introduction portion 421, which will be described later, to the cannula 50. Above the holding portion 44, a predetermined internal space 45 is provided and communicates with the first connection portion 42. The chemical solution introduced from the first connection portion 42 is introduced into the internal space 45 and then flows to the cannula 50 along the holding portion 44.

[0041] The first connection portion 42 includes a chemical solution introduction portion 421, a first seal portion 422, a first housing portion 423, a support portion 424, and a second housing portion 425. The first connection portion 42 communicates with the internal space 45 of the port body 41.

[0042] The chemical solution introduction portion 421 has a communication passage 421a that extends outward from the internal space 45. The chemical solution introduction portion 421 is a flow path for guiding the chemical solution sent out from the liquid delivery port 16 through the first housing portion 423 to the holding portion 44. The communication passage 421a of the chemical solution introduction portion 421 has a proximal end communicating with the internal space 45, and a hollow cylindrical plug body 421b is arranged at the distal end (the end opposite to the internal space 45).

[0043] The cylindrical plug body 421b is a hollow member having an opening hole 421c at its tip. The cylindrical plug body 421b is attached to the tip of the communication passage 421a with a part of its tip exposed to the outside. When the first housing portion 423 is in the closed position, the cylindrical plug body 421b has the opening hole 421c in close contact with a sealing portion 423d provided on the base end surface of the first housing portion 423. Thereby, the chemical solution introduction portion 421 is blocked from communicating with the outside. Similar to the first seal portion 422, the cylindrical plug body 421b can be made of a material having flexibility and sealing properties. Thereby, when the first housing portion 423 is in the open position, the cylindrical plug body 421b can be in close contact with the end surface of the first housing portion 423 provided with the second communication hole 423c, so that the chemical solution introduction portion 421 and the first housing portion 423 can be connected in a liquid-tight manner. Further, when the first housing portion 423 is in the closed position, the cylindrical plug body 421b can be in close contact with the sealing portion 423d, so that the chemical solution introduction portion 421 can be reliably blocked and the internal space 45 can be sealed.

[0044] Note that the aforementioned "closed position" is the moving position of the first housing portion 423 for closing the communication passage 421a and blocking the fluid connection between the liquid supply port 16 and the connection port 40 in a state where the apparatus main body 101 is not mounted on the cradle 30. Further, the "open position" is the moving position of the first housing portion 423 for opening the communication passage 421a and fluidly connecting the liquid supply port 16 and the connection port 40 in a state where the apparatus main body 101 is mounted on the cradle 30.

[0045] The first housing portion 423 is a hollow cylindrical member having a lumen 423a, and is rotatably supported by a support portion 424 with respect to the port body 41. The shape of the base end side of the first housing portion 423 is formed along the outer shape of the surface facing the liquid supply port 16 of the port body 41. Thereby, during the rotation operation, the first housing portion 423 can pivotally move in the Z direction with the support portion 424 as a fulcrum without getting caught on the port body 41.

[0046] On the front end face of the first housing portion 423, a first communication hole 423b communicating with the outside is provided, and on the proximal end side, a second communication hole 423c capable of communicating with the communication passage 421a of the chemical solution introduction portion 421 is provided. The inner cavity 423a of the first housing portion 423 communicates with the liquid delivery hole 16a of the liquid delivery port 16 attached to the first communication hole 423b. Thereby, when the first housing portion 423 is in the open position, the chemical solution sent out from the liquid delivery port 16 flows into the chemical solution introduction portion 421 through the second communication hole 423c.

[0047] The first housing portion 423 is provided with a sealing portion 423d on the proximal end side. The sealing portion 423d blocks the communication with the outside of the chemical solution introduction portion 421. Specifically, the sealing portion 423d is provided around the opening of the chemical solution introduction portion 421. When the first housing portion 423 is in the closed position, the sealing portion 423d blocks the communication with the outside of the chemical solution introduction portion 421 by closely adhering to the cylindrical plug body 421b covering the inner peripheral surface of the opening of the chemical solution introduction portion 421. In the first embodiment, the sealing portion 423d is provided on the inner surface side of a connecting portion 424b, which will be described later, on the proximal end side of the first housing portion 423.

[0048] As shown in FIG. 4, when the first housing portion 423 is in the closed position, the sealing portion 423d and the cylindrical plug body 421b are in close contact. Specifically, as shown in FIG. 4, when the first housing portion 423 rotates and moves the support portion 424, and the tip of the first housing portion 423 (the first communication hole 423b) interlocked with the support portion 424 faces obliquely upward, the sealing portion 423d and the cylindrical plug body 421b are in close contact. When the first housing portion 423 is in the closed position, the sealing portion 423d closely adheres to cover the end face (opening hole 421c) of the cylindrical plug body 421b. Thereby, the internal space 45 is sealed in a state where the apparatus main body 101 is not mounted on the cradle 30.

[0049] Further, the first communication hole 423b faces the detachment direction D2 of the apparatus main body 101 when the first housing portion 423 is in the closed position. For this reason, since the user can easily insert the liquid delivery port 16 into the first communication hole 423b, the apparatus main body 101 can be easily mounted on the cradle 30.

[0050] As shown in FIG. 5, when the first housing portion 423 is in the open position, the second communication hole 423c communicates with the opening hole 421c of the cylindrical plug body 421b. Specifically, when the first housing portion 423 rotates and moves the support portion 424, and the tip (first communication hole 423b) of the first housing portion 423 interlocked with the support portion 424 faces in the X direction, the second communication hole 423c communicates with the opening hole 421c of the cylindrical plug body 421b. When the first housing portion 423 is in the open position, the sealing portion 423d covers at least a part of the end face of the cylindrical plug body 421b and exposes the opening hole 421c to the inner cavity 423a side. Thereby, the opening hole 421c communicates with the second communication hole 423c. In the open position, the apparatus main body 101 and the cradle 30 are in a completely mounted state. The internal space 45 communicates with the liquid supply port 16 when the apparatus main body 101 is completely mounted on the cradle 30, and a chemical liquid flow path is established. That is, the liquid supply port 16 (liquid supply pipe 14) and the connection port 40 are fluid-connected.

[0051] An engagement groove 423e that engages with an engagement claw 425b of a second housing portion 425 described later is provided on the outer periphery of the first housing portion 423. The engagement groove 423e is at least one annular groove that circulates along the outer periphery of the first housing portion 423.

[0052] The first seal portion 422 is disposed in the vicinity of the first communication hole 423b in the inner cavity 423a of the first housing portion 423. The first seal portion 422 is in close contact with the outer periphery of the tip portion of the liquid supply port 16 mounted on the first communication hole 423b. Therefore, the first seal portion 422 can enhance the liquid tightness in the connection state between the liquid supply port 16 and the first housing portion 423. The first seal portion 422 can be an O-ring made of a material having flexibility and sealing properties such as a rubber material or a thermoplastic elastomer.

[0053] The support portion 424 is rotatably supported in the circumferential direction of the support shaft 41a provided on the port body 41 and is connected to the first housing portion 423. In the first embodiment, the support portion 424 is integrally provided on the first housing portion 423. The support portion 424 has a substantially U-shaped planar view shape (shape viewed from the Z direction) so as to cover at least a part of three directions around the port body 41. The support portion 424 includes a pair of base portions 424a disposed to face each other with the port body 41 interposed therebetween, and a connecting portion 424b provided so that the base portions 424a are integrated continuously on the tip end side of the pair of base portions 424a. The first housing portion 423 is provided at a substantially central portion of the connecting portion 424b. The second communication hole 423c of the first housing portion 423 is provided to penetrate the connecting portion 424b. In the connecting portion 424b, a portion located below the second communication hole 423c and formed in a shape along the periphery of the opening of the chemical solution introduction portion 421 functions as a sealing portion 423d.

[0054] Note that the support portion 424 only needs to have a function of supporting the first housing portion 423 movably between a closed position and an open position with respect to the port body 41, and thus its shape and the like are not particularly limited. Further, in the first embodiment, although the first housing portion 423 and the support portion 424 are described as separate configurations, the first housing portion 423 can also be made of a member constituting the first housing portion 423.

[0055] The second housing portion 425 is attached so as to cover the tip end portion of the first housing portion 423. A mounting hole 425a into which the liquid feed port 16 is inserted and which communicates with the first communication hole 423b is provided at a substantially central portion of the second housing portion 425. When the second housing portion 425 and the first housing portion 423 are in the open position, the mounting hole 425a coincides with the opening position of the first communication hole 423b in the axial direction of the first housing portion 423. Thereby, when the second housing portion 425 is attached to the first housing portion 423, the mounting hole 425a communicates with the first communication hole 423b. The first seal portion 422 is held between the second housing portion 425 and the first housing portion 423, and is sealed in a liquid-tight manner between the first seal portion 422 and the outer periphery of the liquid feed port 16.

[0056] On the outer periphery of the second housing portion 425, a plurality of engaging claws 425b are provided so as to protrude toward the proximal end side. When the second housing portion 425 is attached to the first housing portion 423, the hook-shaped portion on the distal end side of the engaging claw 425b engages with the engaging groove 423e of the first housing portion 423. Note that the number and formation position of the engaging claws 425b are not particularly limited, but in consideration of the mounting stability during attachment, it is preferable to provide an equal angular pitch in the circumferential direction of the second housing portion 425.

[0057] The second connection portion 43 includes an opening hole 431 and a plug body 432. After the cannula 50 is inserted into the living body together with the puncture needle, only the puncture needle is punctured and removed. The opening hole 431 is provided on the upper surface of the port body 41. The plug body 432 is disposed directly below the opening hole 431.

[0058] The plug body 432 is disposed above the holding portion 44 and at a position facing the proximal end of the cannula 50. The plug body 432 can be made of a flexible and sealable material such as various rubber materials such as silicone rubber and natural rubber, and various thermoplastic elastomers such as polyurethane-based, polyester-based, polyamide-based, olefin-based, and styrene-based. After removing the puncture needle that has passed through the plug body 432, the plug body 432 seals the second connection portion 43 to separate the internal space 45 from the external environment.

[0059] <Operation> Next, in the chemical solution administration device 100 according to the first embodiment, the operation when the first main body portion 10 is attached to the cradle 30 and the operation when the first main body portion 10 is detached from the cradle 30 will be described with reference to FIGS. 6 to 9.

[0060] As a preliminary step before using the liquid medicine administration device 100, the user attaches the cradle 30 to the living body surface and inserts the cannula 50 into the living body. When inserting the cannula 50, while the user attaches the adhesive portion 31c of the cradle 30 to the skin, the user punctures the puncture needle from the second connection portion 43 and inserts the cannula 50 into the living body. Thereby, the cradle 30 is attached to the living body surface with the cannula 50 being inserted into the living body.

[0061] Next, the user attaches the second main body portion 20 to the first main body portion 10 to assemble the device main body 101. As shown in FIG. 6, the first housing portion 423 of the connection port 40 faces obliquely upward (upper right in the figure), which is the detachment direction D2 of the device main body 101, in a state before attaching the device main body 101 to the cradle 30. That is, in a state before attaching the device main body 101 to the cradle 30, the first housing portion 423 of the connection port 40 is located at the closed position. Thereby, the communication passage 421a is closed with the cylindrical plug body 421b being in close contact with the sealing portion 423d of the first housing portion 423, and the communication with the outside is blocked. Therefore, the internal space 45 of the connection port 40 is in a sealed state.

[0062] As shown in FIG. 7, the user brings the assembled device main body 101 close to the cradle 30 from obliquely upward (upper right in the figure) in the mounting direction D1 (lower right direction in the figure), engages the first guide portion 11e with the second guide portion 31d, and inserts the liquid supply port 16 into the mounting hole 425a of the second housing portion 425 and attaches it to the first housing portion 423. Thereby, the device main body 101 is temporarily attached to the cradle 30. As shown in FIG. 7, in the temporarily attached state of the device main body 101 and the cradle 30, the liquid supply port 16 is attached to and communicates with the first housing portion 423. However, as shown in FIG. 7, since the first housing portion 423 is located at the closed position, the cylindrical plug body 421b and the sealing portion 423d are in close contact with each other and are in a closed state. Therefore, the internal space 45 of the connection port 40 remains in a sealed state even in the state of FIG. 7.

[0063] Subsequently, as shown in FIG. 8, the user brings the bottom surface portion 101a (bottom surface portion 11a) of the apparatus main body 101 closer to the placement surface portion 31a of the cradle 30 from the temporarily attached state of the apparatus main body 101 and the cradle 30, and mounts the apparatus main body 101 on the cradle 30. Specifically, the user moves the apparatus main body 101, which is temporarily attached to the cradle 30 obliquely upward, downward with the support portion 424 as the rotation center, and places the bottom surface portion 101a of the apparatus main body 101 on the placement surface portion 31a. Further, the support portion 424 rotates as the apparatus main body 101 moves, and moves the direction of the first housing portion 423 from obliquely upward to face the X direction. As a result, the first housing portion 423 moves from the closed position to the open position. Thereby, the connection port 40 becomes in an open state, a chemical solution flow path in which the internal space 45 and the liquid supply port 16 communicate with each other is formed, and chemical solution administration by the chemical solution administration device 100 becomes possible.

[0064] The chemical solution flow path is a flow path that connects to the cannula 50 inside the connection port 40. For this reason, the liquid supply pipe 14 connected to the reservoir 12 and the cannula 50 punctured into the living body are fluid-connected. Therefore, if the user activates the chemical solution administration device 100, the liquid supply drive unit 23 is driven at a predetermined timing to allow the chemical solution stored in the reservoir 12 to flow into the inside of the first housing portion 423 from the liquid supply port 16 through the liquid supply pipe 14. Then, the chemical solution that has flowed into the inside of the first housing portion 423 flows from the internal space 45 of the port body 41 through the chemical solution introduction portion 421 into the cannula 50 and is introduced into the living body.

[0065] When detaching the first main body 10 from the cradle 30 during the use of the chemical solution administration device 100, as shown in FIG. 9, the user lifts the device main body 101 upward with the support portion 424 as the rotation center in the direction opposite to the state where the device main body 101 is completely mounted on the cradle 30, and separates the device main body 101 from the cradle 30 in the detachment direction D2 (the upper right direction in the figure) opposite to the mounting direction D1. As a result, the device main body 101 detaches from the cradle 30, the liquid feeding port 16 comes off from the second housing portion 425 of the first connection portion 42, and the connection state is released. Further, as the device main body 101 detaches, the first housing portion 423 moves from the open position to the closed position. When the first housing portion 423 moves to the closed position, the cylindrical plug body 421b comes into close contact with the sealing portion 423d. Thereby, the connection port 40 is in a sealed state, the internal space 45 is sealed, and the communication with the outside is blocked.

[0066] [Second Embodiment] Next, the chemical solution administration device 110 according to the second embodiment will be described with reference to FIG. 10. In the second embodiment, components having the same functions as those in the first embodiment described above are denoted by the same reference numerals, and detailed descriptions thereof are omitted. For configurations, members, usage methods, etc. that are not particularly mentioned, they may be the same as those in the above-described embodiments.

[0067] [Configuration] In the chemical solution administration device 110 according to the second embodiment, the support portion 424 is configured to be biased by a biasing member 424c so that the first housing portion 423 is located at the closed position.

[0068] Specifically, as shown in FIG. 10, the support portion 424 includes a biasing member 424c. The biasing member 424c is arranged on the support shaft 41a and is composed of a member (such as a torsion coil spring) capable of applying a biasing force in a predetermined direction to the support portion 424. In a state where the apparatus main body 111 and the cradle 30 are not attached, the support portion 424 is biased by the biasing force of the biasing member 424c so that the first communication hole 423b of the first housing portion 423 faces the separation direction D2. Thereby, in a state where the apparatus main body 111 and the cradle 30 are not attached, the first housing portion 423 can always be positioned at the closed position. Therefore, the sealing portion 423d and the cylindrical plug body 421b are in close contact with each other, and the closed state of the chemical solution introduction portion 421 is maintained. Further, when the apparatus main body 111 is completely attached to the cradle 30, the support portion 424 rotates against the biasing force of the biasing member 424c and moves the first housing portion 423 to the open position.

[0069] In the chemical solution administration device 110 according to the second embodiment, the mounting direction D1 when the first main body portion 10 is mounted on the cradle 30 is a direction from above the cradle 30 obliquely downward. Therefore, in the chemical solution administration device 110 according to the second embodiment, the operations when the apparatus main body 111 is temporarily mounted and mounted on the cradle 30 are the same as those in the first embodiment (see FIGS. 6 to 8).

[0070] In the chemical solution administration device 110 of the second embodiment, the detachment direction D2 for detaching the device main body 111 from the cradle 30 is a direction along the X direction (right direction in FIG. 10). In the chemical solution administration device 110 according to the second embodiment, the support portion 424 is biased by the biasing member 424c so that the first housing portion 423 is positioned at the closed position. Therefore, even if the detachment direction D2 of the device main body 111 is a direction along the X direction, after the device main body 111 is detached, the support portion 424 can move the first housing portion 423 from the open position to the closed position by the biasing force of the biasing member 424c. Therefore, when detaching the device main body 111 from the cradle 30, the chemical solution administration device 110 according to the second embodiment only needs to slide the mounted device main body 111 along the X direction, and the attachment / detachment operation becomes simple. Further, since the support portion 424 is biased by the biasing member 424c so that the first housing portion 423 is positioned at the closed position, even when the device main body 111 is not mounted on the cradle 30, the flow with the outside of the connection port 40 is always blocked, and the sealed state of the internal space 45 can be maintained.

[0071] In the second embodiment, the detachment direction D2 of the device main body 111 is a direction along the X direction. However, similar to the first embodiment, it may be a direction opposite to the attachment direction D1.

[0072] The operation of the chemical solution administration device 110 according to the second embodiment having the above configuration until the device main body 111 is completely mounted on the cradle 30 is the same as the operation of the chemical solution administration device 100 according to the first embodiment described above (see FIGS. 6 to 8).

[0073] When detaching the first main body 10 from the cradle 30 during the use of the chemical solution administration device 110, the user slides the device main body 111 in the detachment direction D2 along the X direction to separate it from the cradle 30. As a result, the device main body 111 detaches from the cradle 30, and the liquid supply port 16 disengages from the first housing portion 423 of the first connection portion 42, releasing the connection state. Further, when the device main body 111 is detached, the first housing portion 423 moves from the open position to the closed position along with the rotational movement of the support portion 424 biased by the biasing member 424c. When the first housing portion 423 moves to the closed position, the cylindrical plug body 421b comes into close contact with the sealing portion 423d. Thereby, the connection port 40 is in a sealed state, the internal space 45 is sealed, and the communication with the outside is blocked.

[0074] [Function and Effect] As described above, the chemical solution administration devices 100 and 110 according to the present embodiment include a connection port 40 for holding the cannula 50 inserted into the living body, a cradle 30 attached to the living body, a reservoir 12 for storing the chemical solution, a liquid supply drive unit 23 for sending out the chemical solution from the reservoir 12, a liquid supply pipe 14 through which the chemical solution sent out from the reservoir 12 flows, and a hollow cylindrical liquid supply port 16 communicating with the liquid supply pipe 14, and have a device main body 101 and 111. The liquid supply port 16 and the connection port 40 are detachably fluid-connected. The connection port 40 includes a chemical solution introduction portion 421 for introducing the chemical solution sent out from the liquid supply pipe 14, and a first housing portion 423 to which the liquid supply port 16 is attached and which is movably attached to the chemical solution introduction portion 421. In a state where the liquid supply port 16 is attached to the first housing portion 423, the first housing portion 423 is configured to be fluid-connected to the liquid supply port 16 by moving relative to the chemical solution introduction portion 421.

[0075] In the prior art, a configuration was adopted in which fluid connection was repeatedly performed by puncturing and removing a liquid delivery needle having a sharp tip with respect to a rubber stopper (septum) provided at a connection port. As a result, in the prior art, as the number of times of attaching and detaching the apparatus main body and the cradle increased, for example, the puncture hole of the rubber stopper widened or the rubber stopper itself was damaged, and there was a risk of leakage of the chemical solution from the connection portion between the rubber stopper and the liquid delivery needle. Further, when the liquid delivery needle could not be punctured in the correct direction with respect to the rubber stopper due to an operation error or the like, the rubber stopper was further damaged. On the other hand, the chemical solution administration devices 100 and 110 according to the present embodiment are configured to send a chemical solution to the connection port 40 through the liquid delivery port 16 of the apparatus main bodies 101 and 111, and are provided with a configuration in which the liquid delivery port 16 and the connection port 40 are fluid-connected by attaching the liquid delivery port 16 to the first housing portion 423. Thereby, the chemical solution administration devices 100 and 110 according to the present embodiment prevent leakage of the chemical solution from the connection port due to damage and deterioration of the rubber stopper, which has been a problem in the prior art. Further, the chemical solution administration devices 100 and 110 can be fluid-connected to the liquid delivery port 16 by relatively moving the first housing portion 423 with respect to the chemical solution introduction portion 421 in a state where the liquid delivery port 16 is attached to the first housing portion 423 (specifically, in a state where the liquid delivery port 16 of the apparatus main bodies 101 and 111 is attached to the connection port 40 of the cradle 30). Thereby, the chemical solution administration devices 100 and 110 can appropriately control the fluid connection between the liquid delivery port 16 and the connection port 40 according to the attached state or the non-attached state of the apparatus main bodies 101 and 111 and the cradle 30.

[0076] Also, in the chemical solution administration devices 100 and 110 according to the present embodiment, the first housing portion 423 includes a lumen 423a, a first communication hole 423b that communicates with one end of the lumen 423a and to which the liquid supply port 16 is attached, and a second communication hole 423c that communicates with the other end of the lumen 423a and can communicate with the chemical solution introduction portion 421. The connection port 40 includes a support portion 424 that rotatably supports the first housing portion 423 with respect to the chemical solution introduction portion 421. The connection port 40 may be configured such that, with the liquid supply port 16 attached to the first housing portion 423, by rotating the support portion 424 in a predetermined direction, the second communication hole 423c communicates with the chemical solution introduction portion 421 and is fluidly connected to the liquid supply port 16.

[0077] According to the chemical solution administration devices 100 and 110 configured in this way, the user can easily fluidly connect the liquid supply port 16 and the connection port 40 by rotating the support portion 424 in a predetermined direction with the liquid supply port 16 attached to the first housing portion 423.

[0078] Further, in the chemical solution administration devices 100 and 110 according to the present embodiment, the chemical solution introduction portion 421 includes a hollow cylindrical plug body 421b that can communicate with the second communication hole 423c. The first housing portion 423 further has a sealing portion 423d that is in close contact with the cylindrical plug body 421b on the base end side and closes the chemical solution introduction portion. The support portion 424 is configured to be rotatable between an open position for fluidly connecting the liquid supply port 16 and the connection port 40 and a closed position for blocking the fluid connection between the liquid supply port 16 and the connection port 40. The connection port 40 is configured such that when the support portion 424 is rotated with the liquid supply port 16 attached to the first housing portion 423 and the first housing portion 423 moves to the closed position, the cylindrical plug body 421b and the sealing portion 423d are in close contact and the fluid connection with the liquid supply port 16 is blocked.

[0079] According to the chemical solution administration devices 100 and 110 configured as described above, the user can rotate and move the support portion 424 so that the first housing portion 423 moves to the closed position with the liquid delivery port 16 attached to the first housing portion 423. As a result, the sealing portion 423d closely adheres to the cylindrical plug body 421b, and the fluid connection between the liquid delivery port 16 and the connection port 40 can be easily blocked.

[0080] Further, in the chemical solution administration device 110 according to the present embodiment, the support portion 424 may be configured to include a biasing member 424c that biases the first housing portion 423 toward the closed position.

[0081] The chemical solution administration device 110 configured as described above includes the biasing member 424c that biases the first housing portion 423 toward the closed position in the support portion 424. Therefore, after the device main body 111 is detached from the cradle 30, the first housing portion 423 can be moved from the open position to the closed position by the biasing force of the biasing member 424c. Accordingly, even when the device main body 111 is not attached to the cradle 30, the connection port 40 is always blocked from communicating with the outside, and the sealed state of the internal space 45 can be maintained. Further, in the chemical solution administration devices 100 and 110 according to the present embodiment, the first housing portion 423 may be configured to include a first seal portion 422 that closely adheres to the outer peripheral surface of the attached liquid delivery port 16 in the vicinity of the first communication hole 423b in the inner cavity 423a.

[0082] According to the chemical solution administration devices 100 and 110 configured as described above, since the first seal portion 422 closely adheres to the outer periphery of the tip of the liquid delivery port 16 attached to the first communication hole 423b, the liquid tightness in the connection state between the liquid delivery port 16 and the first housing portion 423 can be enhanced.

[0083] This application is based on Japanese Patent Application No. 2021-050937 filed on March 25, 2021, the disclosure of which is incorporated herein by reference in its entirety.

Explanation of Reference Numerals

[0084] 10 First main body part, 12 Reservoir, 14 Liquid delivery pipe, 16 Liquid delivery port, 20 Second main body part, 23 Liquid delivery drive part, 30 Cradle, 40 Connection port, 42 First connection part (421 Chemical solution introduction part, 421b Cylindrical plug body, 422 First seal part, 423 First housing part, 423a Inner cavity of the first housing part, 423b First communication hole, 423c Second communication hole, 423d Sealing part, 424 Support part, 424c Biasing member), 43 Second connection part, 50 Cannula, 100, 110 Chemical solution administration device, 101, 111 Device main body (101a Bottom surface part), D1 Mounting direction, D2 Dismounting direction.

Claims

1. A connection port for holding a cannula to be inserted into a living body is attached, a cradle to be attached to the living body, a reservoir for storing a chemical solution, a liquid delivery driving unit for delivering the chemical solution from the reservoir, a liquid delivery pipe through which the chemical solution delivered from the reservoir flows, and a hollow cylindrical liquid delivery port communicating with the liquid delivery pipe, and an apparatus main body having the same, The chemical solution administration device is configured such that the liquid delivery port and the connection port are detachably fluid-connected, The connection port includes a chemical solution introduction part for introducing the chemical solution delivered from the liquid delivery pipe, and a first housing part to which the liquid delivery port is attached and which is movably attached to the chemical solution introduction part, The chemical solution administration device is configured such that, in a state where the liquid delivery port is attached to the first housing part, the first housing part is relatively moved with respect to the chemical solution introduction part so as to be fluid-connected to the liquid delivery port.

2. The first housing part includes a lumen, a first communication hole communicating with one end of the lumen and to which the liquid delivery port is attached, and a second communication hole communicating with the other end of the lumen and capable of communicating with the chemical solution introduction part, The connection port includes a support part that is connected to the first housing part and rotatably supports the first housing part with respect to the chemical solution introduction part, The chemical solution administration device according to claim 1, wherein, in a state where the liquid delivery port is attached to the first housing part, the second communication hole communicates with the chemical solution introduction part and is fluid-connected to the liquid delivery port by rotating and moving the support part in a predetermined direction.

3. The chemical solution introduction part includes a hollow cylindrical plug body capable of communicating with the second communication hole, The first housing part further has a sealing part that is in close contact with the cylindrical plug body on the proximal end side and closes the chemical solution introduction part, and is configured to be rotatably movable by the support part between an open position for fluid-connecting the liquid delivery port and the connection port and a closed position for blocking the fluid connection between the liquid delivery port and the connection port, The chemical solution administration device according to claim 2, wherein, in a state where the liquid delivery port is attached to the first housing part, when the support part is rotated and moved and the first housing part moves to the closed position, the cylindrical plug body and the sealing part are in close contact with each other and the fluid connection with the liquid delivery port is blocked.

4. The chemical liquid administration device according to claim 3, wherein the support portion includes a biasing member that biases the first housing portion toward the closed position.

5. The chemical liquid administration device according to any one of claims 2 to 4, wherein the first housing portion includes a first seal portion that is in close contact with an outer peripheral surface of the mounted liquid supply port in the vicinity of the first communication hole in the inner cavity.

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