How to remove and disinfect

Abstract

To provide a method for removing and sterilizing stains containing protein, and a peracetic acid-containing cleaning composition for use in the method.SOLUTION: The present invention discloses a method for removing and sterilizing stains containing protein, including bringing a peracetic acid-containing cleaning composition into contact with a cleaning object, the peracetic acid-containing cleaning composition containing at least peracetic acid and hydrogen peroxide. There is also provided a peracetic acid-containing cleaning composition for use in the method.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to a method for removing and disinfecting, and more particularly to a method for removing and disinfecting protein-containing soils. [Background technology]

[0002] Conventionally, surfactant-based detergent compositions have been used as liquid detergent compositions for cleaning medical instruments, tableware, cooking utensils, etc. in the fields of medicine and food processing (Patent Document 1). Some of these conventional detergent compositions have bactericidal activity, but the bactericidal effect is extremely small. When strong bactericidal activity is required, bactericidal detergent compositions that combine a cationic surfactant as a bactericidal component with a nonionic surfactant or amphoteric surfactant as a cleaning component are used to simultaneously achieve both sterilization and cleaning. However, it is widely known that the bactericidal performance of this type of bactericidal detergent composition is significantly reduced when contaminants such as proteins are mixed in.

[0003] Therefore, there is still a need for a sterilizing and cleaning method that is excellent in both dirt removal and disinfecting properties for objects to be sterilized and cleaned that have a mixture of dirt such as protein and microorganisms such as bacteria attached thereto, and a cleaning composition to be used in that method. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Japanese Patent Application Laid-Open No. 2012-140483 Summary of the Invention [Problem to be solved by the invention]

[0005] There is a need for a method for removing and disinfecting protein-containing soils and cleaning compositions for use in the method. [Means for solving the problem]

[0006] As a result of extensive research, the inventors have discovered that it is possible to provide a sterilizing and cleaning method that is excellent in both dirt removal and disinfecting properties for objects to be sterilized and cleaned that have a mixture of dirt such as protein and microorganisms such as bacteria attached thereto, as well as a cleaning composition to be used in said method.

[0007] That is, the present invention includes the following embodiments. <1> 1. A method for removing and disinfecting protein-containing soils, comprising contacting an object to be cleaned with a peracetic acid-containing cleaning composition, wherein the peracetic acid-containing cleaning composition comprises at least peracetic acid and hydrogen peroxide. <2> Further, the method includes contacting a hydrogen peroxide decomposer with the object to be cleaned. <1> The method described below. <3> The contacting of the hydrogen peroxide decomposer with the object to be cleaned is carried out before, after, or simultaneously with the contacting of the peracetic acid-containing cleaning composition with the object to be cleaned. <1> or <2> The method described below. <4> The peracetic acid-containing cleaning composition contains peracetic acid in an amount of 50 to 1000 ppm and hydrogen peroxide in an amount of 20 to 60000 ppm. <1> ~ <3> A method according to any one of the preceding claims. <5> At least one of the peracetic acid-containing cleaning composition and the hydrogen peroxide decomposer further contains a surfactant. <1> ~ <4> A method according to any one of the preceding claims. <6> The peracetic acid-containing cleaning composition contains 1 to 50,000 ppm of a surfactant. <5> The method described below. <7> The hydrogen peroxide decomposer contains a surfactant in an amount of 1 to 50,000 ppm. <5> The method described below. <8> <1> ~ <7> A cleaning composition containing peracetic acid for use in any one of the methods described above. [Effects of the Invention]

[0008] According to the present invention, it is possible to provide a sterilizing and cleaning method that is excellent in both dirt removal and disinfection properties for objects to be sterilized and cleaned that have a mixture of dirt such as protein and microorganisms such as bacteria attached thereto, and a cleaning composition to be used in said method. DETAILED DESCRIPTION OF THE INVENTION

[0009] The present invention provides a method for removing and disinfecting, more particularly, a method for removing and disinfecting protein-containing stains. In one embodiment of the present invention, the method for removing and disinfecting protein-containing stains comprises contacting an object to be cleaned with a cleaning composition containing peracetic acid. In another embodiment of the present invention, the method for removing and disinfecting protein-containing stains further comprises contacting an object to be cleaned with a hydrogen peroxide decomposer. The present invention also provides a cleaning composition containing peracetic acid for use in the method for removing and disinfecting protein-containing stains of the present invention.

[0010] The peracetic acid-containing cleaning composition and hydrogen peroxide decomposer used in the method of the present invention will now be described.

[0011] 1. Peracetic acid-containing cleaning composition In the method of the present invention, the peracetic acid-containing cleaning composition comprises at least peracetic acid and hydrogen peroxide. In one embodiment of the present invention, the peracetic acid-containing cleaning composition comprises peracetic acid and hydrogen peroxide.

[0012] (1) Peracetic acid In the method of the present invention, the peracetic acid-containing cleaning composition contains peracetic acid. The peracetic acid used in the peracetic acid-containing cleaning composition of the present invention may be any peracetic acid commonly used in the art.

[0013] In the method of the present invention, the concentration of peracetic acid in the peracetic acid-containing cleaning composition may be 50 to 1000 ppm. In one embodiment of the present invention, the concentration of peracetic acid in the peracetic acid-containing cleaning composition may be, for example, 50 ppm, 60 ppm, 70 ppm, 80 ppm, 90 ppm, 100 ppm, 110 ppm, 120 ppm, 130 ppm, 140 ppm, 150 ppm, 200 ppm, 250 ppm, 300 ppm, 350 ppm, 400 ppm, 450 ppm, 500 ppm, 550 ppm, 600 ppm, 650 ppm, 700 ppm, 750 ppm, 800 ppm, 850 ppm, 900 ppm, 950 ppm, 1000 ppm, etc., but is not limited thereto.

[0014] In one embodiment of the present invention, the concentration of peracetic acid in the peracetic acid-containing cleaning composition is, for example, 50~1000ppm, 50~950ppm, 50~900ppm, 50~850ppm, 50~800ppm, 50~750ppm, 50~70 0ppm, 50~650ppm, 50~600ppm, 50~550ppm, 50~500ppm, 50~450ppm, 50~400ppm, 50 ~350ppm, 50~300ppm, 50~250ppm, 50~200ppm, 50~150ppm, 50~140ppm, 50~130ppm , 50~120ppm, 50~110ppm, 50~100ppm, 50~90ppm, 50~80ppm, 50~70ppm, 50~60ppm, 60~1000ppm, 60~950ppm, 60~900ppm, 60~850ppm, 60~800ppm, 60~750ppm, 60~ 700ppm, 60~650ppm, 60~600ppm, 60~550ppm, 60~500ppm, 60~450ppm, 60~400ppm m, 60~350ppm, 60~300ppm, 60~250ppm, 60~200ppm, 60~150ppm, 60~140ppm, 60~130ppm, 60~120ppm, 60~110ppm, 60~100ppm, 60~90ppm, 60~80ppm, 60~70ppm, 70~1000ppm、70~950ppm、70~900ppm、70~850ppm、70~800ppm、70~750ppm、70~700ppm、70~650ppm、70~600ppm、70~550ppm、70~500ppm、70~450ppm、70~400ppm、70~350ppm、70~300ppm、70~250ppm、70~200ppm、70~150ppm、70~140ppm、70~130ppm、70~120ppm、70~110ppm、70~100ppm、70~90ppm、70~80ppm、 80~1000ppm、80~950ppm、80~900ppm、80~850ppm、80~800ppm、80~750ppm、80~700ppm、80~650ppm、80~600ppm、80~550ppm、80~500ppm、80~450ppm、80~400ppm、80~350ppm、80~300ppm、80~250ppm、80~200ppm、80~150ppm、80~140ppm、80~130ppm、80~120ppm、80~110ppm、80~100ppm、80~90ppm、 90~1000ppm、90~950ppm、90~900ppm、90~850ppm、90~800ppm、90~750ppm、90~700ppm、90~650ppm、90~600ppm、90~550ppm、90~500ppm、90~450ppm、90~400ppm、90~350ppm、90~300ppm、90~250ppm、90~200ppm、90~150ppm、90~140ppm、90~130ppm、90~120ppm、90~110ppm、90~100ppm、

[0015] 100~1000ppm、100~950ppm、100~900ppm、100~850ppm、100~800ppm、100~750ppm、100~700ppm、100~650ppm、100~600ppm、100~550ppm、100~500ppm、100~450ppm、100~400ppm、100~350ppm、100~300ppm、100~250ppm、100~200ppm、100~150ppm、100~140ppm、100~130ppm、100~120ppm、100~110ppm、 110~1000ppm、110~950ppm、110~900ppm、110~850ppm、110~800ppm、110~750ppm、110~700ppm、110~650ppm、110~600ppm、110~550ppm、110~500ppm、110~450ppm、110~400ppm、110~350ppm、110~300ppm、110~250ppm、110~200ppm、110~150ppm、110~140ppm、110~130ppm、110~120ppm、 120~1000ppm、120~950ppm、120~900ppm、120~850ppm、120~800ppm、120~750ppm、120~700ppm、120~650ppm、120~600ppm、120~550ppm、120~500ppm、120~450ppm、120~400ppm、120~350ppm、120~300ppm、120~250ppm、120~200ppm、120~150ppm、120~140ppm、120~130ppm、 130~1000ppm、130~950ppm、130~900ppm、130~850ppm、130~800ppm、130~750ppm、130~700ppm、130~650ppm、130~600ppm、130~550ppm、130~500ppm、130~450ppm、130~400ppm、130~350ppm、130~300ppm、130~250ppm、130~200ppm、130~150ppm、130~140ppm、 140~1000ppm、140~950ppm、140~900ppm、140~850ppm、140~800ppm、140~750ppm、140~700ppm、140~650ppm、140~600ppm、140~550ppm、140~500ppm、140~450ppm、140~400ppm、140~350ppm、140~300ppm、140~250ppm、140~200ppm、140~150ppm、 150~1000ppm、150~950ppm、150~900ppm、150~850ppm、150~800ppm、150~750ppm、150~700ppm、150~650ppm、150~600ppm、150~550ppm、150~500ppm、150~450ppm、150~400ppm、150~350ppm、150~300ppm、150~250ppm、150~200ppm、

[0016] 200~1000ppm、200~950ppm、200~900ppm、200~850ppm、200~800ppm、200~750ppm、200~700ppm、200~650ppm、200~600ppm、200~550ppm、200~500ppm、200~450ppm、200~400ppm、200~350ppm、200~300ppm、200~250ppm、 250~1000ppm、250~950ppm、250~900ppm、250~850ppm、250~800ppm、250~750ppm、250~700ppm、250~650ppm、250~600ppm、250~550ppm、250~500ppm、250~450ppm、250~400ppm、250~350ppm、250~300ppm、 300~1000ppm、300~950ppm、300~900ppm、300~850ppm、300~800ppm、300~750ppm、300~700ppm、300~650ppm、300~600ppm、300~550ppm、300~500ppm、300~450ppm、300~400ppm、300~350ppm、 350~1000ppm、350~950ppm、350~900ppm、350~850ppm、350~800ppm、350~750ppm、350~700ppm、350~650ppm、350~600ppm、350~550ppm、350~500ppm、350~450ppm、350~400ppm、 400~1000ppm、400~950ppm、400~900ppm、400~850ppm、400~800ppm、400~750ppm、400~700ppm、400~650ppm、400~600ppm、400~550ppm、400~500ppm、400~450ppm、 450~1000ppm、450~950ppm、450~900ppm、450~850ppm、450~800ppm、450~750ppm、450~700ppm、450~650ppm、450~600ppm、450~550ppm、450~500ppm、

[0017] 500~1000ppm、500~950ppm、500~900ppm、500~850ppm、500~800ppm、500~750ppm、500~700ppm、500~650ppm、500~600ppm、500~550ppm、 550~1000ppm、550~950ppm、550~900ppm、550~850ppm、550~800ppm、550~750ppm、550~700ppm、550~650ppm、550~600ppm、 600~1000ppm、600~950ppm、600~900ppm、600~850ppm、600~800ppm、600~750ppm、600~700ppm、600~650ppm、 650~1000ppm、650~950ppm、650~900ppm、650~850ppm、650~800ppm、650~750ppm、650~700ppm、 700~1000ppm、700~950ppm、700~900ppm、700~850ppm、700~800ppm、700~750ppm、 750~1000ppm, 750~950ppm, 750~900ppm, 750~850ppm, 750~800ppm, 800~1000ppm, 800~950ppm, 800~900ppm, 800~850ppm, 850~1000ppm, 850~950ppm, 850~900ppm, 900~1000ppm, 900~950ppm, 950~1000ppm, In one embodiment of the present invention, the concentration of peracetic acid in the peracetic acid-containing cleaning composition may be preferably 50 to 900 ppm, more preferably 100 to 600 ppm, and even more preferably 200 to 500 ppm.

[0018] (2) Hydrogen peroxide In the method of the present invention, the peracetic acid-containing cleaning composition contains hydrogen peroxide. In the peracetic acid-containing cleaning composition of the present invention, hydrogen peroxide itself has sterilizing and cleaning properties, and therefore not only contributes to enhancing the sterilizing and cleaning effects of the entire composition, but also contributes to the production and maintenance of a sufficient amount of peracetic acid (stability in aqueous solution) through the equilibrium reaction between peracetic acid and acetic acid. Therefore, the combination of peracetic acid and hydrogen peroxide can further enhance the sterilizing and cleaning effects of the composition of the present invention. The hydrogen peroxide used in the peracetic acid-containing cleaning composition of the present invention can be any hydrogen peroxide commonly used in the art.

[0019] In the method of the present invention, the concentration of hydrogen peroxide in the peracetic acid-containing cleaning composition may be 20 to 60,000 ppm. In one embodiment of the present invention, the concentration of hydrogen peroxide in the peracetic acid-containing cleaning composition may be, for example, 20 ppm, 30 ppm, 50 ppm, 60 ppm, 70 ppm, 80 ppm, 90 ppm, 100 ppm, 120 ppm, 150 ppm, 200 ppm, 300 ppm, 400 ppm, 500 ppm, 600 ppm, 700 ppm, 800 ppm, 900 ppm, 1000 ppm, 2000 ppm, or m, 3000 ppm, 4000 ppm, 5000 ppm, 6000 ppm, 7000 ppm, 8000 ppm, 9000 ppm, 10000 ppm, 15000 ppm, 18000 ppm, 20000 ppm, 25000 ppm, 30000 ppm, 35000 ppm, 40000 ppm, 45000 ppm, 50000 ppm, 60000 ppm, and the like.

[0020] In one embodiment of the present invention, the concentration of hydrogen peroxide in the peracetic acid-containing cleaning composition is, for example, 20~60000ppm, 20~50000ppm, 20~45000ppm, 20~40000ppm, 20~35000ppm, 20~30000ppm, 20~25000ppm, 20~20000ppm, 20 ~18000ppm, 20~15000ppm, 20~10000ppm, 20~9000ppm, 20~8000ppm, 20~7000ppm, 20~6000ppm, 20~5000ppm, 20~4000ppm , 20~3000ppm, 20~2000ppm, 20~1000ppm, 20~900ppm, 20~800ppm, 20~700ppm, 20~600ppm, 20~500ppm, 20~400ppm, 20~30 0ppm, 20~200ppm, 20~150ppm, 20~120ppm, 20~100ppm, 20~90ppm, 20~80ppm, 20~70ppm, 20~60ppm, 20~50ppm, 20~30ppm, 30~60000ppm、30~50000ppm、30~45000ppm、30~40000ppm、30~35000ppm、30~30000ppm、30~25000ppm、30~20000ppm、30~18000ppm、30~15000ppm、30~10000ppm、30~9000ppm、30~8000ppm、30~7000ppm、30~6000ppm、30~5000ppm、30~4000ppm、30~3000ppm、30~2000ppm、30~1000ppm、30~900ppm、30~800ppm、30~700ppm、30~600ppm、30~500ppm、30~400ppm、30~300ppm、30~200ppm、30~150ppm、30~120ppm、30~100ppm、30~90ppm、30~80ppm、30~70ppm、30~60ppm、30~50ppm、 50~60000ppm、50~50000ppm、50~45000ppm、50~40000ppm、50~35000ppm、50~30000ppm、50~25000ppm、50~20000ppm、50~18000ppm、50~15000ppm、50~10000ppm、50~9000ppm、50~8000ppm、50~7000ppm、50~6000ppm、50~5000ppm、50~4000ppm、50~3000ppm、50~2000ppm、50~1000ppm、50~900ppm、50~800ppm、50~700ppm、50~600ppm、50~500ppm、50~400ppm、50~300ppm、50~200ppm、50~150ppm、50~120ppm、50~100ppm、50~90ppm、50~80ppm、50~70ppm、50~60ppm、 60~60000ppm、60~50000ppm、60~45000ppm、60~40000ppm、60~35000ppm、60~30000ppm、60~25000ppm、60~20000ppm、60~18000ppm、60~15000ppm、60~10000ppm、60~9000ppm、60~8000ppm、60~7000ppm、60~6000ppm、60~5000ppm、60~4000ppm、60~3000ppm、60~2000ppm、60~1000ppm、60~900ppm、60~800ppm、60~700ppm、60~600ppm、60~500ppm、60~400ppm、60~300ppm、60~200ppm、60~150ppm、60~120ppm、60~100ppm、60~90ppm、60~80ppm、60~70ppm、

[0021] 70~60000ppm、70~50000ppm、70~45000ppm、70~40000ppm、70~35000ppm、70~30000ppm、70~25000ppm、70~20000ppm、70~18000ppm、70~15000ppm、70~10000ppm、70~9000ppm、70~8000ppm、70~7000ppm、70~6000ppm、70~5000ppm、70~4000ppm、70~3000ppm、70~2000ppm、70~1000ppm、70~900ppm、70~800ppm、70~700ppm、70~600ppm、70~500ppm、70~400ppm、70~300ppm、70~200ppm、70~150ppm、70~120ppm、70~100ppm、70~90ppm、70~80ppm、 80~60000ppm、80~50000ppm、80~45000ppm、80~40000ppm、80~35000ppm、80~30000ppm、80~25000ppm、80~20000ppm、80~18000ppm、80~15000ppm、80~10000ppm、80~9000ppm、80~8000ppm、80~7000ppm、80~6000ppm、80~5000ppm、80~4000ppm、80~3000ppm、80~2000ppm、80~1000ppm、80~900ppm、80~800ppm、80~700ppm、80~600ppm、80~500ppm、80~400ppm、80~300ppm、80~200ppm、80~150ppm、80~120ppm、80~100ppm、80~90ppm、 90~60000ppm、90~50000ppm、90~45000ppm、90~40000ppm、90~35000ppm、90~30000ppm、90~25000ppm、90~20000ppm、90~18000ppm、90~15000ppm、90~10000ppm、90~9000ppm、90~8000ppm、90~7000ppm、90~6000ppm、90~5000ppm、90~4000ppm、90~3000ppm、90~2000ppm、90~1000ppm、90~900ppm、90~800ppm、90~700ppm、90~600ppm、90~500ppm、90~400ppm、90~300ppm、90~200ppm、90~150ppm、90~120ppm、90~100ppm、 100~60000ppm、100~50000ppm、100~45000ppm、100~40000ppm、100~35000ppm、100~30000ppm、100~25000ppm、100~20000ppm、100~18000ppm、100~15000ppm、100~10000ppm、100~9000ppm、100~8000ppm、100~7000ppm、100~6000ppm、100~5000ppm、100~4000ppm、100~3000ppm、100~2000ppm、100~1000ppm、100~900ppm、100~800ppm、100~700ppm、100~600ppm、100~500ppm、100~400ppm、100~300ppm、100~200ppm、100~150ppm、100~120ppm、

[0022] 120~60000ppm、120~50000ppm、120~45000ppm、120~40000ppm、120~35000ppm、120~30000ppm、120~25000ppm、120~20000ppm、120~18000ppm、120~15000ppm、120~10000ppm、120~9000ppm、120~8000ppm、120~7000ppm、120~6000ppm、120~5000ppm、120~4000ppm、120~3000ppm、120~2000ppm、120~1000ppm、120~900ppm、120~800ppm、120~700ppm、120~600ppm、120~500ppm、120~400ppm、120~300ppm、120~200ppm、120~150ppm、 150~60000ppm、150~50000ppm、150~45000ppm、150~40000ppm、150~35000ppm、150~30000ppm、150~25000ppm、150~20000ppm、150~18000ppm、150~15000ppm、150~10000ppm、150~9000ppm、150~8000ppm、150~7000ppm、150~6000ppm、150~5000ppm、150~4000ppm、150~3000ppm、150~2000ppm、150~1000ppm、150~900ppm、150~800ppm、150~700ppm、150~600ppm、150~500ppm、150~400ppm、150~300ppm、150~200ppm、 200~60000ppm、200~50000ppm、200~45000ppm、200~40000ppm、200~35000ppm、200~30000ppm、200~25000ppm、200~20000ppm、200~18000ppm、200~15000ppm、200~10000ppm、200~9000ppm、200~8000ppm、200~7000ppm、200~6000ppm、200~5000ppm、200~4000ppm、200~3000ppm、200~2000ppm、200~1000ppm、200~900ppm、200~800ppm、200~700ppm、200~600ppm、200~500ppm、200~400ppm、200~300ppm、 300~60000ppm、300~50000ppm、300~45000ppm、300~40000ppm、300~35000ppm、300~30000ppm、300~25000ppm、300~20000ppm、300~18000ppm、300~15000ppm、300~10000ppm、300~9000ppm、300~8000ppm、300~7000ppm、300~6000ppm、300~5000ppm、300~4000ppm、300~3000ppm、300~2000ppm、300~1000ppm、300~900ppm、300~800ppm、300~700ppm、300~600ppm、300~500ppm、300~400ppm、

[0023] 400~60000ppm、400~50000ppm、400~45000ppm、400~40000ppm、400~35000ppm、400~30000ppm、400~25000ppm、400~20000ppm、400~18000ppm、400~15000ppm、400~10000ppm、400~9000ppm、400~8000ppm、400~7000ppm、400~6000ppm、400~5000ppm、400~4000ppm、400~3000ppm、400~2000ppm、400~1000ppm、400~900ppm、400~800ppm、400~700ppm、400~600ppm、400~500ppm、 500~60000ppm、500~50000ppm、500~45000ppm、500~40000ppm、500~35000ppm、500~30000ppm、500~25000ppm、500~20000ppm、500~18000ppm、500~15000ppm、500~10000ppm、500~9000ppm、500~8000ppm、500~7000ppm、500~6000ppm、500~5000ppm、500~4000ppm、500~3000ppm、500~2000ppm、500~1000ppm、500~900ppm、500~800ppm、500~700ppm、500~600ppm、 600~60000ppm、600~50000ppm、600~45000ppm、600~40000ppm、600~35000ppm、600~30000ppm、600~25000ppm、600~20000ppm、600~18000ppm、600~15000ppm、600~10000ppm、600~9000ppm、600~8000ppm、600~7000ppm、600~6000ppm、600~5000ppm、600~4000ppm、600~3000ppm、600~2000ppm、600~1000ppm、600~900ppm、600~800ppm、600~700ppm、 700~60000ppm、700~50000ppm、700~45000ppm、700~40000ppm、700~35000ppm、700~30000ppm、700~25000ppm、700~20000ppm、700~18000ppm、700~15000ppm、700~10000ppm、700~9000ppm、700~8000ppm、700~7000ppm、700~6000ppm、700~5000ppm、700~4000ppm、700~3000ppm、700~2000ppm、700~1000ppm、700~900ppm、700~800ppm、

[0024] 800~60000ppm、800~50000ppm、800~45000ppm、800~40000ppm、800~35000ppm、800~30000ppm、800~25000ppm、800~20000ppm、800~18000ppm、800~15000ppm、800~10000ppm、800~9000ppm、800~8000ppm、800~7000ppm、800~6000ppm、800~5000ppm、800~4000ppm、800~3000ppm、800~2000ppm、800~1000ppm、800~900ppm、 900~60000ppm、900~50000ppm、900~45000ppm、900~40000ppm、900~35000ppm、900~30000ppm、900~25000ppm、900~20000ppm、900~18000ppm、900~15000ppm、900~10000ppm、900~9000ppm、900~8000ppm、900~7000ppm、900~6000ppm、900~5000ppm、900~4000ppm、900~3000ppm、900~2000ppm、900~1000ppm、 1000~60000ppm、1000~50000ppm、1000~45000ppm、1000~40000ppm、1000~35000ppm、1000~30000ppm、1000~25000ppm、1000~20000ppm、1000~18000ppm、1000~15000ppm、1000~10000ppm、1000~9000ppm、1000~8000ppm、1000~7000ppm、1000~6000ppm、1000~5000ppm、1000~4000ppm、1000~3000ppm、1000~2000ppm、 2000~60000ppm、2000~50000ppm、2000~45000ppm、2000~40000ppm、2000~35000ppm、2000~30000ppm、2000~25000ppm、2000~20000ppm、2000~18000ppm、2000~15000ppm、2000~10000ppm、2000~9000ppm、2000~8000ppm、2000~7000ppm、2000~6000ppm、2000~5000ppm、2000~4000ppm、2000~3000ppm、

[0025] 3000~60000ppm、3000~50000ppm、3000~45000ppm、3000~40000ppm、3000~35000ppm、3000~30000ppm、3000~25000ppm、3000~20000ppm、3000~18000ppm、3000~15000ppm、3000~10000ppm、3000~9000ppm、3000~8000ppm、3000~7000ppm、3000~6000ppm、3000~5000ppm、3000~4000ppm、 4000~60000ppm、4000~50000ppm、4000~45000ppm、4000~40000ppm、4000~35000ppm、4000~30000ppm、4000~25000ppm、4000~20000ppm、4000~18000ppm、4000~15000ppm、4000~10000ppm、4000~9000ppm、4000~8000ppm、4000~7000ppm、4000~6000ppm、4000~5000ppm、 5000~60000ppm、5000~50000ppm、5000~45000ppm、5000~40000ppm、5000~35000ppm、5000~30000ppm、5000~25000ppm、5000~20000ppm、5000~18000ppm、5000~15000ppm、5000~10000ppm、5000~9000ppm、5000~8000ppm、5000~7000ppm、5000~6000ppm、 6000~60000ppm、6000~50000ppm、6000~45000ppm、6000~40000ppm、6000~35000ppm、6000~30000ppm、6000~25000ppm、6000~20000ppm、6000~18000ppm、6000~15000ppm、6000~10000ppm、6000~9000ppm、6000~8000ppm、6000~7000ppm、

[0026] 7000~60000ppm、7000~50000ppm、7000~45000ppm、7000~40000ppm、7000~35000ppm、7000~30000ppm、7000~25000ppm、7000~20000ppm、7000~18000ppm、7000~15000ppm、7000~10000ppm、7000~9000ppm、7000~8000ppm、 8000~60000ppm、8000~50000ppm、8000~45000ppm、8000~40000ppm、8000~35000ppm、8000~30000ppm、8000~25000ppm、8000~20000ppm、8000~18000ppm、8000~15000ppm、8000~10000ppm、8000~9000ppm、 9000~60000ppm、9000~50000ppm、9000~45000ppm、9000~40000ppm、9000~35000ppm、9000~30000ppm、9000~25000ppm、9000~20000ppm、9000~18000ppm、9000~15000ppm、9000~10000ppm、 10000~60000ppm、10000~50000ppm、10000~45000ppm、10000~40000ppm、10000~35000ppm、10000~30000ppm、10000~25000ppm、10000~20000ppm、10000~18000ppm、10000~15000ppm、

[0027] 15000~60000ppm、15000~50000ppm、15000~45000ppm、15000~40000ppm、15000~35000ppm、15000~30000ppm、15000~25000ppm、15000~20000ppm、15000~18000ppm、 18000~60000ppm、18000~50000ppm、18000~45000ppm、18000~40000ppm、18000~35000ppm、18000~30000ppm、18000~25000ppm、18000~20000ppm、 20000~60000ppm, 20000~50000ppm, 20000~45000ppm, 20000~40000ppm, 20000~35000ppm, 20000~30000ppm, 20000~25000ppm, 25000~60000ppm, 25000~50000ppm, 25000~45000ppm, 25000~40000ppm, 25000~35000ppm, 25000~30000ppm, 30000~60000ppm, 30000~50000ppm, 30000~45000ppm, 30000~40000ppm, 30000~35000ppm, 35000~60000ppm, 35000~50000ppm, 35000~45000ppm, 35000~40000ppm, 40000~60000ppm, 40000~50000ppm, 40000~45000ppm, 45000~60000ppm, 45000~50000ppm, 50,000 to 60,000 ppm, In one embodiment of the present invention, the concentration of hydrogen peroxide in the peracetic acid-containing cleaning composition may be preferably 20 to 55,000 ppm, more preferably 30 to 20,000 ppm, even more preferably 80 to 18,000 ppm, and even more preferably 100 to 5,000 ppm. If the hydrogen peroxide concentration is too low, the amount of peracetic acid produced by the equilibrium reaction with acetic acid may be insufficient, and the sterilizing and cleaning effects of the present invention may not be fully exhibited. On the other hand, if the hydrogen peroxide concentration is too high, the effects will not be enhanced and may even pose safety problems.

[0028] (3) Surfactants In another embodiment of the present invention, the peracetic acid-containing cleaning composition may further contain a surfactant in addition to peracetic acid and hydrogen peroxide. Examples of surfactants that can be used in the peracetic acid-containing cleaning composition include nonionic surfactants such as polyoxyethylene alkyl ethers and polyoxyethylene alkyl esters, anionic surfactants such as alkylbenzene sulfonates and alkyl sulfates, cationic surfactants such as laurylamine and stearyltrimethylammonium chloride, and amphoteric surfactants such as betaine-type carboxylic acids and sulfate esters.

[0029] In one embodiment of the present invention, the concentration of the surfactant in the peracetic acid-containing cleaning composition may be 1 to 50,000 ppm. In one embodiment of the present invention, the concentration of the surfactant in the peracetic acid-containing cleaning composition may be, for example, 1 ppm, 5 ppm, 10 ppm, 20 ppm, 30 ppm, 40 ppm, 50 ppm, 60 ppm, 70 ppm, 80 ppm, 90 ppm, 100 ppm, 120 ppm, 150 ppm, 200 ppm, 300 ppm, 400 ppm, 500 ppm, 600 ppm, 700 ppm, 800 ppm, 900 ppm. , 1000 ppm, 2000 ppm, 3000 ppm, 4000 ppm, 5000 ppm, 6000 ppm, 7000 ppm, 8000 ppm, 9000 ppm, 10000 ppm, 15000 ppm, 18000 ppm, 20000 ppm, 25000 ppm, 30000 ppm, 35000 ppm, 40000 ppm, 45000 ppm, 50000 ppm, etc. In one embodiment of the present invention, the concentration of the surfactant in the peracetic acid-containing cleaning composition may be, but is not limited to, 10 to 10000 ppm, more preferably 100 to 7000 ppm, and even more preferably 1000 to 5000 ppm. In the present invention, by having the surfactant concentration in the peracetic acid-containing cleaning composition within the above range, the bactericidal power can be improved and excessive decomposition of peracetic acid can be suppressed.

[0030] (4) Other ingredients The peracetic acid-containing cleaning composition used in the method of the present invention may further contain additives used in general disinfecting and cleaning agents, such as stabilizers, thickeners, fragrances, colorants, hydrolases, etc., as needed. In the peracetic acid-containing cleaning composition of the present invention, the remainder other than peracetic acid, hydrogen peroxide, an optional surfactant, and additives added as needed is mainly water. Examples of stabilizers include, but are not limited to, phosphorus-based stabilizers, carboxylic acid-based stabilizers, and stannates.

[0031] The peracetic acid-containing cleaning composition used in the method of the present invention can be used as is without dilution, or can be diluted to any concentration to form a diluted peracetic acid-containing cleaning composition. Water is typically used as the diluent. Examples of water that can be used as the diluent include pure water, ultrapure water, distilled water, purified water, water for injection, and tap water. The dilution ratio is not particularly limited as long as it allows the diluted peracetic acid-containing cleaning composition to have a concentration that exhibits sterilizing and cleaning effects, but is preferably 1 to 10,000 times, and more preferably 1 to 1,000 times.

[0032] (5) Method for producing a peracetic acid-containing cleaning composition and a diluted peracetic acid-containing cleaning composition In one embodiment of the present invention, a method for preparing a peracetic acid-containing cleaning composition comprises mixing at least the following components: (i) peracetic acid; (ii) hydrogen peroxide; (iii) an optional surfactant; The method may include a mixing step of mixing the above components. Each component is as described above. The order in which the components are mixed may be arbitrary, and in the peracetic acid-containing cleaning composition used in the method of the present invention, the mixed components are in an equilibrium state. As described above, the peracetic acid-containing diluted cleaning composition can be obtained by diluting the peracetic acid-containing cleaning composition with a diluent.

[0033] 2. Hydrogen peroxide decomposer (1) Hydrogen peroxide decomposition component Examples of hydrogen peroxide decomposing components that can be contained in the hydrogen peroxide decomposing agent that can be used in the method of the present invention include, but are not limited to, enzymes, heavy metals, reducing agents, oxidizing agents, and the like.

[0034] The enzyme that is the hydrogen peroxide decomposing component is not particularly limited as long as it decomposes hydrogen peroxide, and examples thereof include catalase, superoxide dismutase, cytochrome oxidase, peroxidase, and glutathione peroxidase.

[0035] The heavy metals that are hydrogen peroxide decomposing components are not particularly limited as long as they decompose hydrogen peroxide, and examples thereof include elemental metals such as iron, cobalt, nickel, cobalt, rubidium, vanadium, manganese, silver, platinum, palladium, and rhodium, as well as chlorides, sulfates, nitrates, organic acid salts, and metal complex salts of these metals. More specifically, examples of iron salts include ferrous sulfate (II), ferric sulfate (III), ferrous chloride (II), ferric chloride (III), ferrous nitrate (II), ferric nitrate (III), iron bromide (II), iron bromide (II, III), iron fluoride (II, III), iron hydroxide (II, III), and iron phosphate (II, III). Examples of cobalt salts include cobalt acetate (II), (III), cobalt carbonate (II), (III), and cobalt oxide ( Examples of rubidium salts include rubidium acetate(II),(III), rubidium carbonate(II), rubidium oxide(II),(III), rubidium sulfate(II),(III), rubidium chloride(II),(III), rubidium bromide(II),(III), and rubidium bromide(II),(III).

[0036] The reducing agent, which is a hydrogen peroxide decomposing component, is not particularly limited as long as it decomposes hydrogen peroxide, and examples thereof include alkali, thiocyanide, thiourea, sodium sulfite, sodium bisulfite, and sodium thiosulfate.

[0037] The oxidizing agent, which is a hydrogen peroxide decomposing component, is not particularly limited as long as it decomposes hydrogen peroxide, and examples thereof include ozone, permanganic acid, and permanganates.

[0038] (2) Surfactants In another embodiment of the present invention, the hydrogen peroxide decomposer may further contain a surfactant in addition to the hydrogen peroxide decomposer component. Examples of surfactants that can be used in the hydrogen peroxide decomposer include nonionic surfactants such as polyoxyethylene alkyl ethers and polyoxyethylene alkyl esters, anionic surfactants such as alkylbenzene sulfonates and alkyl sulfates, cationic surfactants such as laurylamine and stearyltrimethylammonium chloride, and amphoteric surfactants such as betaine-type carboxylic acids and sulfate esters.

[0039] In one embodiment of the present invention, the concentration of the surfactant in the hydrogen peroxide decomposer may be 1 to 50,000 ppm, for example, 1 ppm, 5 ppm, 10 ppm, 20 ppm, 30 ppm, 40 ppm, 50 ppm, 60 ppm, 70 ppm, 80 ppm, 90 ppm, 100 ppm, 120 ppm, 150 ppm, 200 ppm, 300 ppm, 400 ppm, 500 ppm, 600 ppm, 700 ppm, 800 ppm, 900 ppm, The surfactant concentration in the hydrogen peroxide decomposer may be, but is not limited to, 1000 ppm, 2000 ppm, 3000 ppm, 4000 ppm, 5000 ppm, 6000 ppm, 7000 ppm, 8000 ppm, 9000 ppm, 10000 ppm, 15000 ppm, 18000 ppm, 20000 ppm, 25000 ppm, 30000 ppm, 35000 ppm, 40000 ppm, 45000 ppm, 50000 ppm, etc. In one embodiment of the present invention, the surfactant concentration in the hydrogen peroxide decomposer may be preferably 10 to 10000 ppm, more preferably 100 to 7000 ppm, and even more preferably 1000 to 5000 ppm. In the present invention, having the surfactant concentration in the hydrogen peroxide decomposer within the above ranges improves foaming during use and reduces residual foam after rinsing.

[0040] (3) Other ingredients The hydrogen peroxide decomposer used in the method of the present invention may further contain additives used in general disinfecting and cleaning agents, such as stabilizers, thickeners, fragrances, colorants, hydrolases, etc., as needed. In the peracetic acid-containing cleaning composition of the present invention, the remainder other than peracetic acid, hydrogen peroxide, optional surfactants, and optional additives is mainly water. Examples of stabilizers include, but are not limited to, phosphorus-based stabilizers, carboxylic acid-based stabilizers, and stannates.

[0041] The hydrogen peroxide decomposer used in the method of the present invention can be used directly without dilution, or diluted to any desired concentration. Water is typically used as the diluent. Examples of the water used as the diluent include pure water, ultrapure water, distilled water, purified water, water for injection, and tap water. The dilution ratio is not particularly limited, as long as it is sufficient to achieve a concentration at which the hydrogen peroxide decomposer can decompose excess hydrogen peroxide, but is preferably 1 to 10,000 times, and more preferably 1 to 1,000 times.

[0042] (5) Manufacturing methods for hydrogen peroxide decomposers and their dilutions In one embodiment of the present invention, a method for producing a hydrogen peroxide decomposer comprises adding at least the following components: (i) a hydrogen peroxide decomposing component; (ii) an optional surfactant; The method may include a mixing step of mixing the above components. Each component is as described above. The order in which the components are mixed may be arbitrary. The diluted hydrogen peroxide decomposer can be obtained by diluting the hydrogen peroxide decomposer with a diluent, as described above.

[0043] 3. Method for removing and disinfecting protein-containing soils using a cleaning composition containing peracetic acid The present invention provides a method for removing and disinfecting protein-containing soils, which comprises contacting an object to be cleaned with a cleaning composition containing peracetic acid.

[0044] In one embodiment of the present invention, the method for removing and disinfecting protein-containing stains of the present invention comprises contacting an object to be cleaned with a peracetic acid-containing cleaning composition, wherein the peracetic acid-containing cleaning composition comprises at least peracetic acid and hydrogen peroxide.

[0045] In another embodiment of the present invention, the method for removing and sterilizing protein-containing stains of the present invention further comprises contacting a hydrogen peroxide decomposer with an object to be cleaned. That is, in another embodiment of the present invention, the method for removing and sterilizing protein-containing stains of the present invention comprises contacting a peracetic acid-containing cleaning composition with an object to be cleaned and contacting a hydrogen peroxide decomposer with the object to be cleaned, wherein the peracetic acid-containing cleaning composition contains at least peracetic acid and hydrogen peroxide. In this embodiment, contacting the hydrogen peroxide decomposer with the object to be cleaned can be carried out before, after, or simultaneously with contacting the peracetic acid-containing cleaning composition with the object to be cleaned. In one embodiment of the present invention, contacting the hydrogen peroxide decomposer with the object to be cleaned can be carried out before contacting the peracetic acid-containing cleaning composition with the object to be cleaned. In one embodiment of the present invention, contacting the hydrogen peroxide decomposer with the object to be cleaned can be carried out after contacting the peracetic acid-containing cleaning composition with the object to be cleaned. In one embodiment of the present invention, the contacting of the hydrogen peroxide decomposer with the object to be cleaned may be carried out simultaneously with the contacting of the peracetic acid-containing cleaning composition with the object to be cleaned. By using the peracetic acid-containing cleaning composition and the hydrogen peroxide decomposer as separate agents in this manner, it is possible to minimize the decrease in the sterilizing effect and the decrease in the stain removing power due to the decomposition of hydrogen peroxide.

[0046] The peracetic acid-containing cleaning composition and hydrogen peroxide decomposer used in the method of the present invention are as described above.

[0047] As described above, the peracetic acid-containing cleaning composition and hydrogen peroxide decomposer used in the method of the present invention can be used as is without dilution, or can be diluted to any desired concentration before contacting the object to be cleaned.

[0048] Examples of objects to be cleaned using the method of the present invention include, but are not limited to, medical instruments, drainage pipes, food and beverage containers, industrial wastewater, cooling water for air conditioning equipment, clothing, food such as cut vegetables, cooking utensils, tableware, bathrooms, kitchens, washing machine drums, bath heaters, furniture, and pets.

[0049] In the method of removing and sterilizing protein-containing stains of the present invention, the contacting may be any of immersion, spraying, coating, liquid passing, circulation, and encapsulation. In the method of removing and sterilizing protein-containing stains of the present invention, the amount of the peracetic acid-containing cleaning composition or diluted peracetic acid-containing cleaning composition used, the amount of the optional hydrogen peroxide decomposer or a diluted product thereof, and the time for removing and sterilizing stains can be appropriately selected depending on the type and amount of microorganisms, the type and amount of protein-containing stains, the concentration of the peracetic acid-containing cleaning composition or diluted peracetic acid-containing cleaning composition, and the concentration of the hydrogen peroxide decomposer or a diluted product thereof.

[0050] In one embodiment of the present invention, the peracetic acid-containing cleaning composition may contain peracetic acid in an amount of 50 to 1000 ppm. In one embodiment of the present invention, the peracetic acid-containing cleaning composition may contain hydrogen peroxide in an amount of 20 to 60000 ppm. In one embodiment of the present invention, the peracetic acid-containing cleaning composition may contain peracetic acid in an amount of 50 to 1000 ppm and hydrogen peroxide in an amount of 20 to 60000 ppm.

[0051] In one embodiment of the present invention, at least one of the peracetic acid-containing cleaning composition and the hydrogen peroxide decomposer may further comprise a surfactant. In one embodiment of the present invention, the peracetic acid-containing cleaning composition may further comprise a surfactant in addition to peracetic acid and hydrogen peroxide. In another embodiment of the present invention, the hydrogen peroxide decomposer may further comprise a surfactant in addition to a hydrogen peroxide decomposing component. In yet another embodiment of the present invention, the peracetic acid-containing cleaning composition and the hydrogen peroxide decomposer may each further comprise a surfactant.

[0052] In one embodiment of the present invention, the surfactant may be contained in the peracetic acid-containing cleaning composition in an amount of 1 to 50,000 ppm.

[0053] In one embodiment of the present invention, the surfactant may be contained in the hydrogen peroxide decomposer in an amount of 1 to 50,000 ppm.

[0054] The peracetic acid-containing cleaning composition used in the method of the present invention is expected to have the effects of removing protein-containing dirt and disinfecting, as well as the effects of removing scale and biofilm, and also has the advantage of being low odor. [Example]

[0055] Examples of the present invention are shown below. However, these examples are merely illustrative of embodiments of the present invention and are not intended to limit the scope of the present invention.

[0056] <Method for measuring hydrogen peroxide concentration in cleaning composition> In the present invention, the hydrogen peroxide concentration of a cleaning composition containing peracetic acid was measured by oxidation-reduction titration. Specifically, approximately 0.1 g of a sample was precisely weighed and placed in a 250 mL Erlenmeyer flask, and 100 mL of pure water and 10 mL of 1.8 mol / L sulfuric acid were added to prepare a test solution. A few drops of ferroin test solution were added to this test solution, and the solution was titrated with a 0.1 mol / L cerium (IV) sulfate solution to calculate the hydrogen peroxide concentration.

[0057] <Method for measuring peracetic acid concentration in cleaning composition> In the present invention, the peracetic acid concentration of the peracetic acid-containing cleaning composition was measured by neutralization titration. Specifically, approximately 0.1 g of a sample of the peracetic acid-containing cleaning composition was precisely weighed and placed in a 100 mL beaker, and approximately 50 mL of pure water was added to prepare a test solution. This test solution was titrated with 0.1 mol / L sodium hydroxide solution, and the peracetic acid concentration was calculated from the amount added from the first inflection point to the second inflection point.

[0058] <Preparation of soiling solution> Frozen pellets (8 × 10) of Escherichia coli (Microbiologics / strain: ATCC8739) 2 CFU) were activated and cultured in LB medium (Kyokuto Pharmaceutical Co., Ltd.) at 35°C for 24 hours. Colonies were collected from the medium and washed twice by centrifugation using sterilized ultrapure water. The supernatant was removed by decantation, and the bacterial cells were diluted to 10 ml with sterilized ultrapure water to prepare a bacterial solution.

[0059] 0.16 g of bovine serum albumin (BSA) (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.) was dissolved in 1.0 ml of sterilized ultrapure water and filtered through a 0.2 μm filter to prepare an aqueous BSA solution.

[0060] 0.10 g of carboxymethylcellulose sodium (CMC-Na) (Fujifilm Wako Pure Chemical Industries, Ltd.), 0.05 g of desoxycholate (DC) powder medium (AS ONE Corporation), and 1.0 ml of sterilized ultrapure water were mixed and heated to melt at 100°C for 15 minutes. After melting, the mixture was allowed to cool to room temperature to prepare a CMC-Na / DC powder medium mixture.

[0061] A stain solution was prepared by mixing 1.0 mL of bacterial solution, 1.0 mL of BSA aqueous solution, 1.0 mL of CMC-Na·DC agar medium mixture, and 1.0 mL of oleic acid (OA) (Tokyo Chemical Industry Co., Ltd.).

[0062] <Creating test pieces> A 5 × 5 cm cutting board piece was cut from a commercially available polyethylene cutting board.

[0063] 0.2 g of the soiling solution prepared as described above was evenly applied to a piece of cutting board, which was then incubated at 35°C for 1 hour to prepare a test piece.

[0064] <Preparation of spray liquid> When the peracetic acid-containing cleaning composition was a peracetic acid aqueous solution containing no surfactant, peracetic acid preparation α (peracetic acid concentration 14 wt%, hydrogen peroxide 5.6 wt%), peracetic acid preparation β (peracetic acid concentration 8.9 wt%, hydrogen peroxide 5.4 wt%), or peracetic acid preparation γ (peracetic acid concentration 0.06 wt%, hydrogen peroxide 5.3 wt%) was adjusted with sterilized ultrapure water to a peracetic acid concentration of 10 to 2000 ppm to prepare a peracetic acid aqueous solution that was a peracetic acid-containing cleaning composition.

[0065] When the peracetic acid-containing cleaning composition is a peracetic acid / surfactant mixture containing a surfactant, the above-mentioned peracetic acid formulation α, peracetic acid formulation β, or peracetic acid formulation γ was diluted with sterilized ultrapure water to a peracetic acid concentration of 50 to 200 ppm and a surfactant component of 0.3 wt %, to prepare a peracetic acid / surfactant mixture that is a peracetic acid-containing cleaning composition.

[0066] <Preparation of hydrogen peroxide decomposer> When catalase was used as the hydrogen peroxide decomposing agent, catalase (MGC Advance Chemical Co., Ltd.) was diluted 100 times to prepare an aqueous catalase solution.

[0067] When vanadium sulfate was used as the hydrogen peroxide decomposing agent, vanadium sulfate (manufactured by Mitsubishi Gas Chemical Trading Co., Ltd.) was diluted 100 times to prepare an aqueous vanadium sulfate solution.

[0068] When ferric sulfate, thiourea, or potassium permanganate was used as the hydrogen peroxide decomposer, ferric sulfate (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.), thiourea (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.), or potassium permanganate (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.) was diluted with sterilized ultrapure water to a concentration of 0.1% by weight to prepare various aqueous solutions.

[0069] <Preparation of surfactant / hydrogen peroxide decomposer mixture> When the cleaning composition containing peracetic acid was a surfactant-catalase mixture, the catalase was adjusted to 1% by weight and the surfactant components to 0.3% by weight with sterilized ultrapure water to prepare a surfactant-catalase mixture, which is a cleaning composition containing peracetic acid.

[0070] When the cleaning composition containing peracetic acid was a surfactant / vanadium sulfate mixture, the vanadium sulfate content was adjusted to 1 wt % and the surfactant component content to 0.3 wt % with sterilized ultrapure water to prepare a surfactant / vanadium sulfate mixture, which is a cleaning composition containing peracetic acid.

[0071] When the peracetic acid-containing cleaning composition was a surfactant-ferric sulfate mixture, a surfactant-thiourea mixture, or a surfactant-potassium permanganate mixture, sterilized ultrapure water was used to prepare a surfactant-ferric sulfate mixture, a surfactant-thiourea mixture, or a surfactant-potassium permanganate mixture, respectively, so that the ferric sulfate (Fujifilm Wako Pure Chemical Industries, Ltd.), thiourea (Fujifilm Wako Pure Chemical Industries, Ltd.), or potassium permanganate (Fujifilm Wako Pure Chemical Industries, Ltd.) concentration was 0.1 wt % and the surfactant component was 0.3 wt %, respectively.

[0072] <Removal and sterilization test> The following removal and sterilization tests A to D were carried out, which are explained in detail below.

[0073] [Table 1]

[0074] <Removal sterilization test A: Peracetic acid solution only> Commercially available spray bottles were filled with 100 mL of the prepared peracetic acid solution and 100 mL of 1.5 mol / L sodium thiosulfate. The 1.5 mol / L sodium thiosulfate was prepared by diluting sodium thiosulfate (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.) with sterilized ultrapure water. The amount of solution sprayed from the spray bottle per spray was 0.8 g.

[0075] The test piece and spray were set so that the distance between the nozzle of the spray and the test piece was 10 cm. After two sprays of peracetic acid solution, the test piece was left to act for 30 seconds. After that, to decompose the peracetic acid and hydrogen peroxide, 1.5 mol / L sodium thiosulfate was sprayed 23 times and left to act for 30 seconds. To wash away the adhering chemicals, 20 mL of sterilized ultrapure water was sprayed using a commercially available pressure-accumulating sprayer.

[0076] <Removal disinfection test B: Peracetic acid / surfactant mixed solution> Commercially available spray bottles were filled with the prepared peracetic acid solution, 1.5 mol / L sodium thiosulfate, and peracetic acid / surfactant mixed solution. 1.5 mol / L sodium thiosulfate was prepared by diluting sodium thiosulfate (Fujifilm Wako Pure Chemical Industries, Ltd.) with sterilized ultrapure water. The amount of solution sprayed from the spray bottle per time was 0.8 g.

[0077] The test piece and spray were set so that there was a 10 cm gap between the nozzle of the spray and the test piece. The peracetic acid / surfactant mixed aqueous solution was sprayed twice and allowed to act for 30 seconds. After that, to decompose the peracetic acid and hydrogen peroxide, 1.5 mol / L sodium thiosulfate (Fujifilm Wako Pure Chemical Industries, Ltd.) was sprayed three times and allowed to act for 30 seconds. To wash away the adhering chemicals, 20 mL of sterilized ultrapure water was sprayed using a commercially available pressure-accumulating sprayer.

[0078] <Removal Sterilization Test C: Peracetic Acid Aqueous Solution and Hydrogen Peroxide Decomposer Aqueous Solution> The prepared aqueous solution of peracetic acid, 1.5 mol / L sodium thiosulfate, and aqueous solution of hydrogen peroxide decomposer were filled into commercially available spray bottles. 1.5 mol / L sodium thiosulfate was prepared by diluting sodium thiosulfate (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.) with sterilized ultrapure water. The amount of solution sprayed from the spray bottle per spray was 0.8 g.

[0079] The test piece and spray were set so that the distance between the nozzle of the spray and the test piece was 10 cm. The peracetic acid solution was sprayed twice and allowed to act for 30 seconds. After that, the hydrogen peroxide decomposer solution was sprayed once and allowed to act for 1 minute. Next, to decompose the peracetic acid and hydrogen peroxide, 0.11.5 mol / L sodium thiosulfate was sprayed three times and allowed to act for 30 seconds. To wash away the adhering chemicals, 20 mL of sterilized ultrapure water was sprayed using a commercially available pressure-accumulating sprayer.

[0080] <Removal and disinfection test D: Peracetic acid solution and surfactant / hydrogen peroxide decomposer mixture> The prepared aqueous solution of peracetic acid, 1.5 mol / L sodium thiosulfate, and surfactant / hydrogen peroxide decomposer mixed solution were filled into commercially available spray bottles. 1.5 mol / L sodium thiosulfate was prepared by diluting sodium thiosulfate (Fujifilm Wako Pure Chemical Industries, Ltd.) with sterilized ultrapure water. The amount of solution sprayed from the spray bottle per time was 0.8 g.

[0081] The test piece and spray were set so that the distance between the nozzle of the spray and the test piece was 10 cm. The peracetic acid solution was sprayed twice and allowed to act for 30 seconds. After that, a surfactant / hydrogen peroxide decomposer mixed solution was sprayed once and allowed to act for 1 minute. Next, to decompose the peracetic acid and hydrogen peroxide, 1.5 mol / L sodium thiosulfate (Fujifilm Wako Pure Chemical Industries, Ltd.) was sprayed 23 times and allowed to act for 30 seconds. To wash away the adhering chemicals, 20 mL of sterilized ultrapure water was sprayed using a commercially available pressure-accumulating sprayer.

[0082] <Average E. coli / coliform count> The untreated test pieces and the test pieces that had been treated with the chemicals were wiped with a swab (manufactured by AS ONE Corporation), and the dirt adhering to the swab was transferred to 10 mL of phosphate buffered saline.

[0083] The liquid containing the soil was diluted appropriately with phosphate-buffered saline so that the number of bacteria per mL was several tens, and then applied to a measurement medium (manufactured by Nissui Pharmaceutical Co., Ltd.). The medium was incubated at 35°C for 24 hours.

[0084] After the incubation, the number of colonies that appeared in the medium was counted in units of several tens. The number of colonies that appeared was multiplied by the dilution factor to calculate the bacterial count (CUF / 25cm). 2 ) was calculated.

[0085] The bacterial reduction rate (%) was calculated using the following formula, and the bactericidal activity was judged according to the following criteria. Bactericidal activity (%) = (number of bacteria on the treated test piece) ÷ (number of bacteria on the untreated test piece) × 100 〇: 90% or more △: Less than 90%, Less than 100% ×:100%

[0086] <Average stain retention rate> The weight of the test piece was measured before and after the test, and the average stain remaining rate (%) was calculated using the following formula, and the removal power was evaluated according to the following criteria. Removal rate (%) = (weight before test) ÷ (weight after test) × 100 〇: 90% or more △: Less than 90%, 80% or more ×: Less than 80%

[0087] <Odor> The odor was judged by human olfactory sense according to the following criteria. 〇: There is a slight odor △: A clear odor is detected ×: Pungent odor

[0088] The details of the materials and instruments used in this application are as follows: ·Escherichia coli: (Microbiologics / Product name: E. coli ATCC8739) LB agar medium: (Kyokuto Pharmaceutical Co., Ltd. / Product name: Premedia Lactose Broth Medium) Bovine serum albumin: (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: Albumin, derived from bovine serum (BSA), low salt concentration / Standard: Biochemical grade / Standard content: 98%+) Sodium carboxymethylcellulose: (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: Sodium carboxymethylcellulose / Standard: Chemical grade / Standard content: 6.5-8.5% (as Na)) Desoxycholate Powdered Medium: (Manufactured by AS ONE Corporation / Product name: Sanispec Powdered Medium Desoxycholate Agar / Powder / Specification: For coliform bacteria measurement / Composition: Desoxycholate agar (45.5 g per 1000 mL of medium), peptone mixture / lactose 10 g each, sodium chloride 5 g, desoxycholate ferrous citrate 1 g, desoxycholate / sodium citrate 1 g each, dipotassium phosphate 2 g, neutral red syrup 33 g, agar 16 g) Oleic acid: (Tokyo Chemical Industry Co., Ltd. / Product name: Oleic acid / Standard content: 85.0% or more) Sodium thiosulfate: (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: Sodium thiosulfate / Specification: Volumetric analysis) Catalase: (MGC Advanced Chemical Co., Ltd. / Product name: Ask Super 25) Vanadium sulfate: (Mitsubishi Gas Chemical Trading Co., Ltd. / Product name: CPR-110) Ferric sulfate: (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: Iron(II) sulfate heptahydrate) Thiourea: (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: Thiourea) Potassium permanganate: (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: Potassium permanganate) Surfactant (benzethonium chloride; KEGG): (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: benzethonium chloride / Standard content: 98%+) Surfactant (sodium dodecyl sulfate; SDS): (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: sodium dodecyl sulfate / Standard content: 95%+) Surfactant (Polyoxyethylene (23) Lauryl Ether; POE (23) LE): (Fujifilm Wako Pure Chemical Industries, Ltd. / Product name: Polyoxyethylene (23) Lauryl Ether / Standard content: <100%) Surfactant (sodium polyoxyalkylene alkyl ether sulfate): (Kao Corporation / Product name: Family Fresh / Standard content: 29% sodium polyoxyalkylene alkyl ether sulfate) Phosphate buffered saline: (As One Corporation / Product name: Phosphate buffered saline / Standard: Sterilized filtration) Swab: (Manufactured by AS ONE Corporation / Product name: Swab test swab (Fine Check) PTC-10) Measurement medium: (Nissui Pharmaceutical Co., Ltd. / Product name: Compact Dry "Nissui" EC / Standard: For measuring E. coli and coliform bacteria)

[0089] Example 1 Peracetic acid preparation (also referred to as "peracetic acid species") α (peracetic acid 14% by mass, hydrogen peroxide 5.6% by mass) was diluted with sterilized ultrapure water as a raw material to prepare an aqueous solution of peracetic acid with the component concentrations shown in Table 2. The resulting aqueous solution of peracetic acid was used to conduct the removal and sterilization test shown in Table 1. The results are shown in Table 2-2.

[0090] <Examples 2 to 11 and Comparative Examples 3 to 6> Aqueous solutions of peracetic acid having the component concentrations shown in Tables 2-1 and 2-2 were prepared in the same manner as in Example 1, except that the raw materials were changed to those shown in Tables 2-1 and 2-2, and the removal sterilization test shown in Table 1 was carried out. The results are shown in Tables 2-1 and 2-2.

[0091] In Tables 2-1 to 2-5, peracetic acid species α to γ ​​are the following peracetic acid preparations. Peracetic acid species α: peracetic acid 14% by mass, hydrogen peroxide 5.6% by mass Peracetic acid species β: peracetic acid 8.9% by mass, hydrogen peroxide 5.4% by mass Peracetic acid species γ: peracetic acid 0.06 mass%, hydrogen peroxide 5.3 mass%

[0092] Example 12 Peracetic acid formulation α (peracetic acid 14% by mass, hydrogen peroxide 5.6% by mass) and KEGG (benzethonium chloride) were diluted with sterilized ultrapure water to prepare aqueous solutions of peracetic acid with the concentrations of ingredients shown in the table. The resulting aqueous solutions of peracetic acid were used to conduct the removal and sterilization tests shown in Table 1. The results are shown in Tables 2-3.

[0093] <Examples 13 to 18> Aqueous solutions of peracetic acid having the component concentrations shown in Table 2-3 were prepared in the same manner as in Example 12, except that the raw materials were changed to those shown in Table 2-3. Using the obtained aqueous solutions of peracetic acid, a removal sterilization test shown in Table 1 was carried out. The results are shown in Table 2-3.

[0094] Example 19 Peracetic acid formulation α (14% by mass peracetic acid, 5.6% by mass hydrogen peroxide) was diluted with sterilized ultrapure water as a raw material to prepare an aqueous solution of peracetic acid with the component concentrations shown in Table 2-4. Separately, a catalase formulation (manufactured by MGC Advanced Chemical Co., Ltd. / trade name: Ask Super) was diluted 100 times to prepare an aqueous solution of hydrogen peroxide decomposer as a hydrogen peroxide decomposer. The resulting aqueous solution of peracetic acid and aqueous solution of hydrogen peroxide decomposer were used to conduct the removal and sterilization tests shown in Table 1. The results are shown in Table 2-4.

[0095] <Examples 20 to 29> Aqueous solutions of peracetic acid and hydrogen peroxide decomposer with the concentrations of components shown in Table 2-4 were prepared in the same manner as in Example 19, except that the raw materials were changed to those shown in Table 2-4. Using the resulting aqueous solutions of peracetic acid and hydrogen peroxide decomposer, a removal and sterilization test shown in Table 1 was conducted. The results are shown in Table 2-4.

[0096] <Examples 30 to 34> Except for using ferric sulfate as the hydrogen peroxide decomposer, an aqueous solution of peracetic acid and an aqueous solution of hydrogen peroxide decomposer with the component concentrations shown in Table 2-5 were prepared in the same manner as in Example 19. Using the obtained aqueous solution of peracetic acid and aqueous solution of hydrogen peroxide decomposer, a removal sterilization test shown in Table 1 was conducted. The results are shown in Table 2-5.

[0097] <Examples 35 to 39> Except for using vanadium sulfate as the hydrogen peroxide decomposer, an aqueous solution of peracetic acid and an aqueous solution of hydrogen peroxide decomposer with the component concentrations shown in Table 2-5 were prepared in the same manner as in Example 19. Using the obtained aqueous solution of peracetic acid and aqueous solution of hydrogen peroxide decomposer, a removal sterilization test shown in Table 1 was carried out. The results are shown in Table 2-5.

[0098] <Examples 40 to 44> Except for using thiourea as the hydrogen peroxide decomposer, an aqueous solution of peracetic acid and an aqueous solution of hydrogen peroxide decomposer with the component concentrations shown in Table 2-5 were prepared in the same manner as in Example 19. Using the obtained aqueous solutions of peracetic acid and hydrogen peroxide decomposer, a removal and sterilization test shown in Table 1 was conducted. The results are shown in Table 2-5.

[0099] <Examples 45 to 49> Except for using potassium permanganate as the hydrogen peroxide decomposer, an aqueous solution of peracetic acid and an aqueous solution of hydrogen peroxide decomposer with the component concentrations shown in Table 2-5 were prepared in the same manner as in Example 19. Using the obtained aqueous solution of peracetic acid and aqueous solution of hydrogen peroxide decomposer, a removal sterilization test shown in Table 1 was conducted. The results are shown in Table 2-5.

[0100] <Comparative Example 1> The condition before the stain removal and sterilization test is shown in Table 2-1.

[0101] <Comparative Example 2> Using sterilized ultrapure water, removal and sterilization test A shown in Table 2 was carried out. The results are shown in Table 2-1.

[0102] [Table 2-1]

[0103] [Table 2-2]

[0104] [Table 2-3]

[0105] [Table 2-4]

[0106] [Table 2-5]

[0107] As described above, the present invention has been shown to provide a disinfecting and cleaning method that is excellent in both dirt removal and sterilization properties for objects to be disinfected and cleaned that have a mixture of dirt such as protein and microorganisms such as bacteria attached thereto, as well as a cleaning composition to be used in the method. Furthermore, the peracetic acid-containing cleaning composition of the present invention is an innovative composition that can improve protein removal power without reducing the scale removal effect that peracetic acid originally has.

Claims

1. A method for removing and disinfecting protein-containing soils, comprising contacting an object to be cleaned with a peracetic acid-containing cleaning composition, wherein the peracetic acid-containing cleaning composition contains at least peracetic acid and hydrogen peroxide, The method further comprises contacting the object to be cleaned with a hydrogen peroxide decomposer; The hydrogen peroxide decomposer is brought into contact with the object to be cleaned before, after, or simultaneously with the peracetic acid-containing cleaning composition, except that the hydrogen peroxide decomposer and the peracetic acid-containing cleaning composition are mixed and then brought into contact with each other. The method, wherein the peracetic acid-containing cleaning composition contains peracetic acid in an amount of 50 to 1,000 ppm and hydrogen peroxide in an amount of 20 to 60,000 ppm.

2. 10. The method of claim 1, wherein at least one of the peracetic acid-containing cleaning composition and the hydrogen peroxide decomposer further comprises a surfactant.

3. The method according to claim 1 or 2, wherein the peracetic acid-containing cleaning composition contains peracetic acid in an amount of 50 to 500 ppm and hydrogen peroxide in an amount of 20 to 20,000 ppm.

4. The method according to claim 2 or 3, wherein the peracetic acid-containing cleaning composition contains 1 to 50,000 ppm of a surfactant.

5. The method according to claim 2 or 3, wherein the hydrogen peroxide decomposer contains a surfactant in an amount of 1 to 50,000 ppm.

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