Composition containing two types of polyglyceryl fatty acid ester and hyaluronic acid

Abstract

To provide a composition that is transparent or slightly translucent even in the case where a composition includes a combination of a hyaluronic acid component and two classes of polyglyceryl fatty acid ester.SOLUTION: The present invention relates to a composition containing (a) at least one kind of optionally selected oil, (b) at least one kind of first polyglyceryl fatty acid ester having an HLB value of more than 11.0, (c) at least one kind of second polyglyceryl fatty acid ester having an HLB value of less than 11.0, (d) at least one kind of hyaluronic acid component, (e) at least one kind of polyol having five or more carbon atoms, and (f) water under several specific conditions, where the composition includes a continuous phase and a dispersion phase, and the dispersion phase has a size of 300nm or less, preferably 200nm or less, and more preferably 100nm or less. The composition according to the present invention can have turbidity of 50 NTU or less, preferably 30 NTU or less, and more preferably 10 NTU or less.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to a composition, preferably a cosmetic or dermatological composition, comprising at least two different types of polyglyceryl fatty acid esters. [Background technology]

[0002] Oil-in-water (O / W) or water-in-oil (W / O) emulsions are well known in the cosmetic and dermatological fields, in particular for the preparation of cosmetic preparations such as milks, creams, tonics, serums or lotions.

[0003] In particular, fine emulsions such as O / W nano- or microemulsions are of particular interest in cosmetics due to their transparent or slightly translucent appearance.

[0004] On the other hand, compositions containing polyglyceryl fatty acid esters are known in the fields of cosmetics and dermatology.Polyglyceryl fatty acid esters can function as surfactants, and therefore can typically be used to prepare emulsions, such as oil-in-water (O / W) or water-in-oil (W / O) emulsions.Polyglyceryl fatty acid esters are preferred for environmental reasons, such as their low environmental impact, compared with polyoxyethylene surfactants.

[0005] WO 2020 / 110716 discloses a composition in the form of a nano- or micro-emulsion having a transparent or slightly translucent appearance and containing two polyglyceryl fatty acid esters.

[0006] On the other hand, hyaluronic acid ingredients such as sodium hyaluronate are known to provide moisturizing benefits. [Prior art documents] [Patent documents]

[0007] [Patent Document 1] International Publication No. 2020 / 110716 Brochure [Non-patent literature]

[0008] [Non-Patent Document 1] Walter Noll's Chemistry and Technology of Silicones (1968), Academic Press [Non-patent document 2] Cosmetics and Toiletries, Vol. 91, January 1976, pp. 27-32, Todd & Byers, Volatile Silicone Fluids for Cosmetics [Non-patent document 3] Satoshi Tomomasa et al., Oil Chemistry, Vol. 37, No. 11 (1988), pp. 48-53 Summary of the Invention [Problem to be solved by the invention]

[0009] However, it has proven difficult to include a hyaluronic acid component in compositions containing two classes of polyglyceryl fatty acid esters, such as those disclosed in WO 2020 / 110716, as they tend not to be transparent or slightly translucent.

[0010] It is an object of the present invention to provide a composition that is clear or slightly translucent, even when the composition contains a combination of a hyaluronic acid component and two classes of polyglyceryl fatty acid esters. [Means for solving the problem]

[0011] The above object of the present invention is to (a) at least one optional oil; (b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, and more preferably greater than 13.0; (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, and more preferably less than 9.0; (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof; (e) at least one polyol having 5 or more carbon atoms, and (f) water A composition comprising: the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition; the mass ratio of (a) the amount of oil to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is less than 0.3; the mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester) / ((b) the amount of the first polyglyceryl fatty acid ester) is greater than 0.01 and less than 0.2; the mass ratio of (e) the amount of polyol having 5 or more carbon atoms to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is greater than 0.1 and less than 5; The composition comprises a continuous phase and a dispersed phase, the dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less. This can be achieved by the composition.

[0012] (a) The oil may be selected from polar oils.

[0013] The amount of (a) oil in the composition according to the invention may be less than 0.7% by weight, preferably less than 0.6% by weight, more preferably less than 0.5% by weight, relative to the total weight of the composition.

[0014] (b) The first polyglyceryl fatty acid ester may contain 2 to 4 glycerol units, preferably 3 or 4 glycerol units, and more preferably 4 glycerol units.

[0015] (b) The fatty acid portion of the first polyglyceryl fatty acid ester may contain 12 or fewer carbon atoms, preferably 11 or fewer carbon atoms, and more preferably 10 or fewer carbon atoms.

[0016] The amount of (b) first polyglyceryl fatty acid ester in the composition according to the present invention may be 0.01% by mass to 5% by mass, preferably 0.1% by mass to 4% by mass, more preferably 1% by mass to 3% by mass, relative to the total mass of the composition.

[0017] (c) The second polyglyceryl fatty acid ester may contain 2 to 4 glycerol units, preferably 2 or 3 glycerol units, and more preferably 2 glycerol units.

[0018] (c) The fatty acid portion of the second polyglyceryl fatty acid ester may contain 14 or more carbon atoms, preferably 16 or more carbon atoms, and more preferably 18 or more carbon atoms.

[0019] The amount of (c) second polyglyceryl fatty acid ester in the composition according to the present invention may be 0.001% by mass to 0.5% by mass, preferably 0.01% by mass to 0.4% by mass, and more preferably 0.1% by mass to 0.3% by mass, relative to the total mass of the composition.

[0020] (d) The hyaluronic acid component can be selected from hyaluronic acid, hydrolyzed hyaluronic acid, acetylated hyaluronic acid, cationic hyaluronic acid, salts thereof, and mixtures thereof.

[0021] The amount of the (d) hyaluronic acid component in the composition according to the present invention may be 0.001% by mass to 5% by mass, preferably 0.01% by mass to 4% by mass, and more preferably 0.1% by mass to 3% by mass, relative to the total mass of the composition.

[0022] (e) The polyol having 5 or more carbon atoms is a diol having 5 or more carbon atoms, preferably a C5-C 10 It may be selected from diols, more preferably pentylene glycol, hexylene glycol, and mixtures thereof.

[0023] The amount of (e) polyol having 5 or more carbon atoms in the composition according to the present invention may be in the range of 0.01% by mass to 7% by mass, preferably 0.1% by mass to 6% by mass, and more preferably 1% by mass to 5% by mass, relative to the total mass of the composition.

[0024] The present invention also relates to a cosmetic method for treating keratinous materials, comprising the step of applying to the keratinous materials a composition according to the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0025] As a result of extensive research, the present inventors have discovered that a transparent or slightly translucent composition can be provided even when the composition contains a combination of hyaluronic acid or a salt thereof and two classes of polyglyceryl fatty acid esters.

[0026] Thus, one aspect of the present invention is (a) at least one optional oil; (b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, and more preferably greater than 13.0; (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, and more preferably less than 9.0; (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof; (e) at least one polyol having 5 or more carbon atoms, and (f) water A composition comprising: the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition; the mass ratio of (a) the amount of oil to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is less than 0.3; the mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester) / ((b) the amount of the first polyglyceryl fatty acid ester) is greater than 0.01 and less than 0.2; the mass ratio of (e) the amount of polyol having 5 or more carbon atoms to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is greater than 0.1 and less than 5; The composition comprises a continuous phase and a dispersed phase, the dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less. It is a composition.

[0027] The compositions according to the present invention can be transparent or slightly translucent due to the small size of the dispersed phase. The compositions according to the present invention can have a turbidity of 50 NTU or less, preferably 30 NTU or less, more preferably 10 NTU or less.

[0028] When the composition according to the present invention contains an oil, it can be in the form of a nano- or microemulsion, despite containing hyaluronic acid or a salt thereof.

[0029] The surfactant system used in the composition according to the invention comprises: at least one first polyglyceryl fatty acid ester having a higher HLB value; at least one second polyglyceryl fatty acid ester having a lower HLB value; The combination may be characterized by:

[0030] The higher HLB value of the first polyglyceryl fatty acid ester can be in a higher HLB value range; The lower HLB value of the second polyglyceryl fatty acid ester can belong to a lower HLB value range; and, The higher HLB value range and the lower HLB value range do not overlap with each other.

[0031] The compositions according to the present invention can be less sticky and therefore less sticky to the touch, and therefore can provide an excellent feel in use, in particular an excellent skin feel after application of the composition.

[0032] The term "sticky" is used herein to mean the property of producing a sticky feeling on the skin.

[0033] The composition according to the present invention can be prepared without using a large amount of energy, such as that required by a homogenizer. Therefore, the composition according to the present invention can be prepared by using a small amount of energy, such as by gently stirring the components of the composition together. Therefore, the composition according to the present invention may be environmentally friendly in consideration of its preparation method.

[0034] The compositions according to the invention are described in more detail below.

[0035] [oil] The composition according to the present invention may comprise (a) at least one oil. If two or more oils are used, they may be the same or different.

[0036] Here, "oil" means a fatty compound or substance that is in the form of a liquid or paste (non-solid) at atmospheric pressure (760 mmHg) and room temperature (25°C). As oils, those commonly used in cosmetics can be used, either alone or in combination. These oils can be volatile or non-volatile.

[0037] The (a) oil may be a non-polar oil, such as a hydrocarbon oil or a silicone oil, a polar oil, such as a vegetable or animal oil, and an ester or ether oil, or a mixture thereof.

[0038] (a) The oil may be selected from the group consisting of oils of vegetable or animal origin, synthetic oils, silicone oils, hydrocarbon oils, and fatty alcohols.

[0039] Examples of vegetable oils include linseed oil, camellia oil, macadamia nut oil, corn oil, mink oil, olive oil, avocado oil, camellia oil, castor oil, safflower oil, jojoba oil, sunflower oil, almond oil, rapeseed oil, sesame oil, soybean oil, peanut oil, and mixtures thereof.

[0040] Examples of animal oils include squalene and squalane.

[0041] Examples of synthetic oils include alkane oils such as isododecane and isohexadecane, ester oils, ether oils, and artificial triglycerides.

[0042] The ester oil is preferably a saturated or unsaturated, linear or branched C1-C 26 Aliphatic mono- or polyacids and saturated or unsaturated linear or branched C1-C 26 They are liquid esters with aliphatic monohydric or polyhydric alcohols, the total number of carbon atoms in these esters being 10 or more.

[0043] Preferably, in the case of esters of monohydric alcohols, at least one of the alcohol and the acid from which the esters of the invention are derived is branched.

[0044] Among the monoesters of monoacids and monohydric alcohols, mention may be made of ethyl palmitate, ethylhexyl palmitate, isopropyl palmitate, dicaprylyl carbonate, alkyl myristates such as isopropyl myristate or ethyl myristate, isocetyl stearate, 2-ethylhexyl isononanoate, isononyl isononanoate, isodecyl neopentanoate, and isostearyl neopentanoate.

[0045] C4~C 22 Dicarboxylic or tricarboxylic acids and C1-C 22 Esters with alcohols, and monocarboxylic, dicarboxylic, or tricarboxylic acids with non-sugar C4-C 26 Esters with dihydroxy, trihydroxy, tetrahydroxy, or pentahydroxy alcohols can also be used.

[0046] Mention may be made, inter alia, of: diethyl sebacate, isopropyl lauroyl sarcosinate, diisopropyl sebacate, bis(2-ethylhexyl) sebacate, diisopropyl adipate, di-n-propyl adipate, dioctyl adipate, bis(2-ethylhexyl) adipate, diisostearyl adipate, bis(2-ethylhexyl) maleate, triisopropyl citrate, triisocetyl citrate, triisostearyl citrate, glyceryl trilactate, glyceryl trioctanoate, trioctyldodecyl citrate, trioleyl citrate, neopentyl glycol diheptanoate, diethylene glycol diisononanoate.

[0047] As ester oil, C6-C 30 , preferably C 12 ~C 22 Sugar esters and diesters of fatty acids can be used. It should be remembered that the term "sugar" refers to an oxygen-bearing hydrocarbon-based compound containing several alcohol functional groups, with or without aldehyde or ketone functional groups, and containing at least four carbon atoms. These sugars may be monosaccharides, oligosaccharides, or polysaccharides.

[0048] Examples of suitable sugars that may be mentioned include sucrose (or saccharose), glucose, galactose, ribose, fucose, maltose, fructose, mannose, arabinose, xylose, and lactose, as well as derivatives thereof, especially alkyl derivatives such as methyl derivatives, for example methylglucose.

[0049] Sugar esters of fatty acids are, in particular, those made by esterifying the aforementioned sugars with linear or branched, saturated or unsaturated C6-C 30 , preferably C 12 ~C 22 They can be selected from the group comprising esters or mixtures of esters with fatty acids, which, when unsaturated, can have 1 to 3 conjugated or non-conjugated carbon-carbon double bonds.

[0050] The esters according to this variant can also be chosen from monoesters, diesters, triesters, tetraesters and polyesters, and mixtures thereof.

[0051] These esters may be, for example, oleate, laurate, palmitate, myristate, behenate, coconut, stearate, linoleate, linolenate, caprate, and arachidonic acid esters, or mixtures thereof, such as, inter alia, mixed esters of oleopalmitate, oleostearate, and palmitostearate, and pentaerythrityl tetraethylhexanoate.

[0052] More particularly, monoesters and diesters are used, especially monooleate or dioleate, stearate, behenate, oleopalmitate, linoleate, linolenate, and oleostearate of sucrose, glucose, or methylglucose.

[0053] An example that may be mentioned is the product sold under the name Glucate® DO by the company Amerchol, which is a methylglucose dioleate.

[0054] Examples of preferred ester oils include diisopropyl adipate, dioctyl adipate, 2-ethylhexyl hexanoate, ethyl laurate, cetyl octanoate, octyldodecyl octanoate, isodecyl neopentanoate, myristyl propionate, 2-ethylhexyl 2-ethylhexanoate, 2-ethylhexyl octanoate, 2-ethylhexyl caprylate / caprate, methyl palmitate, ethyl palmitate, isopropyl palmitate, dicaprylate carbonate, and the like. Examples of the glycerin-based glycerin include glyceryl lauroyl sarcosinate, isononyl isononanoate, ethylhexyl palmitate, isohexyl laurate, hexyl laurate, isocetyl stearate, isopropyl isostearate, isopropyl myristate, isodecyl oleate, glyceryl tri(2-ethylhexanoate), pentaerythrityl tetra(2-ethylhexanoate), 2-ethylhexyl succinate, diethyl sebacate, and mixtures thereof.

[0055] Examples of artificial triglycerides include caprylic / caprylyl glyceride, glyceryl trimyristate, glyceryl tripalmitate, glyceryl trilinolenate, glyceryl trilaurate, glyceryl tricaprate, glyceryl tricaprylate, capric / caprylic triglyceride, and capric / caprylic / linolenic triglyceride.

[0056] Examples of silicone oils include linear organopolysiloxanes such as dimethylpolysiloxane, methylphenylpolysiloxane, and methylhydrogenpolysiloxane, cyclic organopolysiloxanes such as cyclohexasiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane, and mixtures thereof.

[0057] Preferably, the silicone oil is chosen from liquid polydialkylsiloxanes, especially liquid polydimethylsiloxanes (PDMS), and liquid polyorganosiloxanes containing at least one aryl group.

[0058] These silicone oils may also be organically modified. The organically modified silicones that can be used according to the present invention are silicone oils as defined above, which contain one or more organic functional groups in their structure that are bonded via hydrocarbon-based groups.

[0059] Organopolysiloxanes are further defined in Walter Noll's Chemistry and Technology of Silicones, Academic Press, 1968. Organopolysiloxanes can be volatile or nonvolatile.

[0060] If volatile, the silicones are more particularly chosen from those having a boiling point between 60° C. and 260° C., and even more particularly chosen from: (i) Cyclic polydialkylsiloxanes containing 3 to 7, preferably 4 to 5, silicon atoms. These include, for example, octamethylcyclotetrasiloxane, sold in particular under the name Volatile Silicone® 7207 by Union Carbide or under the name Silbione® 70045 V2 by Rhodia, decamethylcyclopentasiloxane, sold in particular under the name Volatile Silicone® 7158 by Union Carbide or under the name Silbione® 70045 V5 by Rhodia, and dodecamethylcyclopentasiloxane, sold under the name Silsoft 1217 by Momentive Performance Materials, as well as mixtures thereof. Mention may also be made of cyclocopolymers of the following formula, such as dimethylsiloxane / methylalkylsiloxane type, such as Silicone Volatile® FZ 3109 sold by Union Carbide:

[0061] [ka]

[0062] Mention may also be made of mixtures of cyclic polydialkylsiloxanes with organosilicon compounds, such as a 50 / 50 mixture of octamethylcyclotetrasiloxane and tetratrimethylsilylpentaerythritol, and a mixture of octamethylcyclotetrasiloxane and oxy-1,1'-bis(2,2,2',2',3,3'-hexatrimethylsilyloxy)neopentane; and (ii) Contains 2 to 9 silicon atoms and has a density of 5 × 10 at 25 °C -6 m 2Linear, volatile polydialkylsiloxanes with a viscosity of 0.1 / s or less. An example is decamethyltetrasiloxane, sold in particular by Toray Silicone under the name SH 200. Silicones belonging to this category are also described in an article published in Cosmetics and Toiletries, Vol. 91, January 1976, pp. 27-32, Todd & Byers, Volatile Silicone Fluids for Cosmetics. The viscosity of the silicones is measured at 25°C according to ASTM Standard 445, Appendix C.

[0063] Non-volatile polydialkylsiloxanes may also be used, these being more particularly chosen from polydialkylsiloxanes, among which mention may be made mainly of polydimethylsiloxanes having trimethylsilyl end groups.

[0064] Among these polydialkylsiloxanes, mention may be made, but is not limited to, the following commercially available products: Silbione® oils of the 47 and 70 047 series or Mirasil® oils sold by the company Rhodia, such as 70 047 V 500 000 oil, oils of the Mirasil® series sold by the company Rhodia; - Dow Corning 200 series oils, e.g. 60000mm 2 DC200 having a viscosity of 1 / s, and Viscasil® oils manufactured by General Electric and certain oils of the SF series manufactured by General Electric (SF 96, SF 18).

[0065] Mention may also be made of polydimethylsiloxanes containing dimethylsilanol end groups, known under the name dimethiconol (CTFA), such as the 48 series oils from Rhodia.

[0066] Among the silicones containing aryl groups, mention may be made of polydiarylsiloxanes, especially polydiphenylsiloxanes, and polyalkylarylsiloxanes, such as phenylsilicone oils.

[0067] Phenylsilicone oils are those having the formula:

[0068] [ka]

[0069] [In the formula, R1~R 10 are, independently of one another, saturated or unsaturated, linear, cyclic or branched C1-C 30 Hydrocarbon groups, preferably C1-C 12 a hydrocarbon group, more preferably a C1 to C6 hydrocarbon group, in particular a methyl, ethyl, propyl, or butyl group; m, n, p, and q are each independently an integer of 0 to 900, inclusive, preferably 0 to 500, inclusive, and more preferably 0 to 100, inclusive; However, the sum of n+m+q is non-zero. The phenyl silicone may be selected from the following:

[0070] Examples that may be mentioned include products sold under the following names: - Rhodia Silbione® oils, 70 641 series; oils of the Rhodorsil® 70 633 and 763 series from the company Rhodia; - Dow Corning 556 Cosmetic Grade Fluid, an oil manufactured by Dow Corning; - Bayer PK series silicones, e.g. PK20 product, - Certain oils of the SF series manufactured by General Electric, such as SF 1023, SF 1154, SF 1250 and SF 1265.

[0071] As the phenyl silicone oil, phenyl trimethicone (wherein R to R 10 is methyl, p, q, and n=0, and m=1).

[0072] The organically modified silicone fluids may contain, inter alia, polyethyleneoxy and / or polypropyleneoxy groups, and thus mention may be made of silicone KF-6017 proposed by Shin-Etsu Chemical Co., Ltd., and the oils Silwet® L722 and L77 manufactured by Union Carbide.

[0073] The hydrocarbon oil can be chosen from: - Linear or branched, optionally cyclic C6-C 16 Lower alkanes. Examples that may be mentioned include hexane, undecane, dodecane, tridecane, and isoparaffins, such as isohexadecane, isododecane, and isodecane; and - linear or branched hydrocarbons containing more than 16 carbon atoms, such as liquid paraffin, liquid petroleum jelly, polydecene and hydrogenated polyisobutenes, such as Parleam®, and squalane.

[0074] Preferred examples of hydrocarbon oils include linear or branched hydrocarbons such as isohexadecane, isododecane, squalane, mineral oils (e.g., liquid paraffin), paraffin, Vaseline or petrolatum, and naphthalenes, hydrogenated polyisobutene, isoeicosane, and decene / butene copolymers, and mixtures thereof.

[0075] The term "aliphatic" in aliphatic alcohols refers to a relatively large number of carbon atoms. Thus, alcohols having 4 or more, preferably 6 or more, and more preferably 12 or more carbon atoms are included within the scope of aliphatic alcohols. Fatty alcohols may be saturated or unsaturated. Fatty alcohols may be linear or branched.

[0076] The aliphatic alcohol may have the structure R-OH, where R is selected from saturated and unsaturated, linear and branched groups containing from 4 to 40 carbon atoms, preferably from 6 to 30 carbon atoms, and more preferably from 12 to 20 carbon atoms. In at least one embodiment, R is selected from C 12 ~C 20 Alkyl groups and C 12 ~C 20 R may be selected from alkenyl groups, which may or may not be substituted with at least one hydroxyl group.

[0077] Examples of fatty alcohols include lauryl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, behenyl alcohol, undecylenyl alcohol, myristyl alcohol, octyldodecanol, hexyldecanol, oleyl alcohol, linoleyl alcohol, palmitoleyl alcohol, arachidonyl alcohol, erucyl alcohol, and mixtures thereof.

[0078] Preferably, the fatty alcohol is a saturated fatty alcohol.

[0079] Thus, fatty alcohols are linear or branched, saturated or unsaturated C6-C 30 Alcohols, preferably linear or branched, saturated C6-C 30 Alcohols, more preferably linear or branched saturated C 12 ~C 20 You can choose from alcohol.

[0080] The term "saturated fatty alcohol" as used herein means an alcohol having a long, saturated aliphatic carbon chain. A saturated fatty alcohol is any linear or branched, saturated C-C 30 Preferably, the alcohol is selected from linear or branched saturated C6-C aliphatic alcohols. 30 Among fatty alcohols, linear or branched saturated C 12 ~C 20Fatty alcohols may be preferably used. Any linear or branched saturated C 16 ~C 20 Aliphatic alcohols are more preferably used. 16 ~C 20 Even more preferably, fatty alcohols can be used.

[0081] Examples of saturated fatty alcohols include lauryl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, behenyl alcohol, undecylenyl alcohol, myristyl alcohol, octyldodecanol, hexyldecanol, and mixtures thereof. In one embodiment, cetyl alcohol, stearyl alcohol, octyldodecanol, hexyldecanol, or mixtures thereof (e.g., cetearyl alcohol) and behenyl alcohol can be used as saturated fatty alcohols.

[0082] According to at least one embodiment, the fatty alcohols used in the compositions according to the invention are preferably chosen from cetyl alcohol, octyldodecanol, hexyldecanol, and mixtures thereof.

[0083] It is also preferred that the (a) oil is selected from oils having a molecular weight of less than 600 g / mol.

[0084] Preferably, the (a) oil has a low molecular weight, such as less than 600 g / mol, and is composed of short chain hydrocarbons (C1 to C 12 ester oils having methyl sarcosine, isopropyl lauroyl sarcosine, isopropyl myristate, isopropyl palmitate, isononyl isononanoate, and ethylhexyl palmitate, silicone oils (volatile silicones such as cyclohexasiloxane), hydrocarbon oils (e.g., isododecane, isohexadecane, and squalane), branched and / or unsaturated fatty alcohols (C 12 ~C 30) type oils, such as octyldodecanol and oleyl alcohol, and ether oils such as dicaprylyl ether.

[0085] The (a) oil may be selected from polar oils, preferably ester oils, more preferably isopropyl myristate, and non-polar oils, preferably ether oils, more preferably dicaprylyl ether.

[0086] The amount of (a) oil in the composition according to the present invention may be 0.001% by mass or more, preferably 0.01% by mass or more, more preferably 0.1% by mass or more, relative to the total mass of the composition.

[0087] The amount of (a) oil in the composition according to the invention may be less than 0.7% by weight, preferably less than 0.6% by weight, more preferably less than 0.5% by weight, relative to the total weight of the composition.

[0088] The amount of (a) oil in the composition according to the present invention may be from 0.001% to less than 0.7% by mass, preferably from 0.01% to less than 0.6% by mass, and more preferably from 0.1% to less than 0.5% by mass, relative to the total mass of the composition.

[0089] [First polyglyceryl fatty acid ester] The composition according to the present invention comprises at least one first polyglyceryl fatty acid ester (b) having an HLB value of greater than 11.0, preferably greater than 12.0, and more preferably greater than 13.0. A single type of first polyglyceryl fatty acid ester (b) may be used, or two or more different types of first polyglyceryl fatty acid esters (b) may be used in combination.

[0090] (b) The first polyglyceryl fatty acid ester can function as a surfactant, particularly a nonionic surfactant.

[0091] (b) The first polyglyceryl fatty acid ester may have an HLB value of greater than 11.0 to 17.0, preferably greater than 12.0 to 16.0, and more preferably greater than 13.0 to 15.0.

[0092] The term HLB ("hydrophilic-lipophilic balance") is well known to those skilled in the art and describes the ratio between hydrophilic and lipophilic moieties in a molecule.

[0093] When two or more (b) first polyglyceryl fatty acid esters are used, the HLB value is determined by a weighted average of the HLB values ​​of all the (b) first polyglyceryl fatty acid esters.

[0094] (b) The first polyglyceryl fatty acid ester can be selected from mono-, di-, tri- and higher esters of saturated or unsaturated fatty acids.

[0095] (b) The first polyglyceryl fatty acid ester preferably contains 2 to 4 glycerol units, preferably 3 or 4 glycerol units, and more preferably 4 glycerol units.

[0096] (b) The fatty acid or fatty acid moiety for the fatty acid portion of the first polyglyceryl fatty acid ester may contain 12 or fewer carbon atoms, preferably 11 or fewer carbon atoms, and more preferably 10 or fewer carbon atoms. (b) The fatty acid or fatty acid moiety for the fatty acid portion of the first polyglyceryl fatty acid ester may contain 4 or more carbon atoms, preferably 6 or more carbon atoms, and more preferably 8 or more carbon atoms. (b) The fatty acid or fatty acid moiety for the fatty acid portion of the first polyglyceryl fatty acid ester may have 4 to 12 carbon atoms, preferably 6 to 11, and more preferably 8 to 10 carbon atoms.

[0097] (b) The fatty acids for the fatty acid portion of the first polyglyceryl fatty acid ester can be saturated or unsaturated and can be selected from caprylic acid, capric acid, and lauric acid.

[0098] (b) The first polyglyceryl fatty acid ester can be selected from the group consisting of PG3 caprate (HLB: about 14), PG4 caprylate (HLB: 14), PG4 laurate (HLB: about 14), PG4 caprate (HLB: 14), PG5 myristate (HLB: 15.4), PG5 stearate (HLB: 15), PG6 caprylate (HLB: 14.6), PG6 caprate (HLB: 13.1), PG6 laurate (HLB: 14.1), PG10 laurate (HLB: 15.2), PG10 myristate (HLB: 14.9), PG10 stearate (HLB: 14.1), PG10 isostearate (HLB: 13.7), PG10 oleate (HLB: 13.0), PG10 coconut fatty acid (HLB: 16), and mixtures thereof.

[0099] (b) It may be preferred that the first polyglyceryl fatty acid ester is selected from the group consisting of PG3 caprate (HLB: about 14), PG4 caprylate (HLB: 14), PG4 laurate (HLB: about 14), PG4 caprate (HLB: 14), and mixtures thereof.

[0100] The amount of (b) the first polyglyceryl fatty acid ester in the composition according to the present invention may be 0.01% by weight or more, preferably 0.1% by weight or more, more preferably 1% by weight or more, relative to the total weight of the composition.

[0101] On the other hand, the amount of (b) the first polyglyceryl fatty acid ester in the composition according to the present invention may be 5% by mass or less, preferably 4% by mass or less, more preferably 3% by mass or less, relative to the total mass of the composition.

[0102] The amount of (b) first polyglyceryl fatty acid ester in the composition according to the present invention may be in the range of 0.01% to 5% by mass, preferably 0.1% to 4% by mass, more preferably 1% to 3% by mass, relative to the total mass of the composition.

[0103] [Second polyglyceryl fatty acid ester] The composition according to the present invention comprises (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, and more preferably less than 9.0. A single type of (c) second polyglyceryl fatty acid ester may be used, or two or more different types of (c) second polyglyceryl fatty acid esters may be used in combination.

[0104] (c) The second polyglyceryl fatty acid ester can function as a surfactant, particularly a nonionic surfactant.

[0105] (c) The second polyglyceryl fatty acid ester may have an HLB value of from 5.0 to less than 11.0, preferably from 6.0 to less than 10.0, and more preferably from 7.0 to less than 9.0.

[0106] When two or more (c) second polyglyceryl fatty acid esters are used, the HLB value is determined by the weighted average of the HLB values ​​of all the (c) second polyglyceryl fatty acid esters.

[0107] (c) The second polyglyceryl fatty acid ester can be selected from mono-, di-, tri- and higher esters of saturated or unsaturated fatty acids.

[0108] (c) The second polyglyceryl fatty acid ester preferably contains 2 to 4 glycerol units, preferably 2 or 3 glycerol units, and more preferably 2 glycerol units.

[0109] (c) The fatty acid or fatty acid moiety for the fatty acid portion of the second polyglyceryl fatty acid ester may contain 14 or more carbon atoms, preferably 16 or more carbon atoms, and more preferably 18 or more carbon atoms. (c) The fatty acid or fatty acid moiety for the fatty acid portion of the second polyglyceryl fatty acid ester may contain 30 or fewer carbon atoms, preferably 24 or fewer carbon atoms, and more preferably 20 or fewer carbon atoms. (c) The fatty acid or fatty acid moiety for the fatty acid portion of the second polyglyceryl fatty acid ester may have 14 to 30, preferably 16 to 24, and more preferably 18 to 20 carbon atoms.

[0110] (c) The fatty acids for the fatty acid portion of the second polyglyceryl fatty acid ester can be saturated or unsaturated and can be selected from myristic acid, stearic acid, isostearic acid, and oleic acid.

[0111] (c) The second polyglyceryl fatty acid ester is PG2 stearate (HLB: 5.0), PG2 distearate (HLB: 4), PG2 isostearate (HLB: 8), PG2 diisostearate (HLB: 3.2), PG2 triisostearate (HLB: 3), PG2 sesquiisostearate (HLB: approximately 4), PG2 oleate (HLB: 8), PG2 sesquioleate (HLB: 5.3), PG3 distearate (HLB: 5), PG3 diisostearate (HLB: 5), PG3 dicocoate (HLB: 7), PG5 hexastearate (HLB: 4.0), PG5 trioleate (HLB: 7.0), PG10 pentaoleate (HLB: 6.4) ), PG2 sesquicaprylate (HLB: about 8), PG2 caprate (HLB: 9.5), PG2 laurate (HLB: 8.5), PG2 myristate (HLB: 10), PG2 isopalmitate (HLB: 9), PG4 oleate (HLB: 10), PG4 stearate (HLB: 9), PG4 isostearate (HLB: 8.2), PG6 distearate (HLB: 8), PG10 distearate (HLB: about 9), PG10 tristearate (HLB: 8), PG10 diisostearate (HLB: 10), PG10 triisostearate (HLB: 8), PG10 tricoconut fatty acid (HLB: 9), and mixtures thereof.

[0112] (c) The second polyglyceryl fatty acid ester is PG2 stearate (HLB: 5.0), PG2 distearate (HLB: 4), PG2 isostearate (HLB: 8), PG2 diisostearate (HLB: 3.2), PG2 triisostearate (HLB: 3), PG2 sesquiisostearate (HLB: approximately 4), PG2 oleate (HLB: 8), PG2 sesquioleate (HLB: 5.3), PG3 distearate (HLB: 5), and diisostearate. In some cases, it may be preferable to select from the group consisting of PG3 (HLB: 5), dicoconut fatty acid PG3 (HLB: 7), sesquicaprylic acid PG2 (HLB: about 8), capric acid PG2 (HLB: 9.5), lauric acid PG2 (HLB: 8.5), myristate PG2 (HLB: 10), isopalmitic acid PG2 (HLB: 9), oleic acid PG4 (HLB: 10), stearate PG4 (HLB: 9), isostearic acid PG4 (HLB: 8.2), and mixtures thereof.

[0113] The amount of (c) the second polyglyceryl fatty acid ester in the composition according to the present invention may be 0.001% by weight or more, preferably 0.01% by weight or more, more preferably 0.1% by weight or more, relative to the total weight of the composition.

[0114] On the other hand, the amount of (c) the second polyglyceryl fatty acid ester in the composition according to the present invention may be 0.5% by mass or less, preferably 0.4% by mass or less, more preferably 0.3% by mass or less, relative to the total mass of the composition.

[0115] The amount of (c) second polyglyceryl fatty acid ester in the composition according to the present invention may be in the range of 0.001% by mass to 0.5% by mass, preferably 0.01% by mass to 0.4% by mass, more preferably 0.1% by mass to 0.3% by mass, relative to the total mass of the composition.

[0116] [Hyaluronic acid ingredient] The composition according to the present invention comprises (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof. A single type of hyaluronic acid component may be used, or two or more different types of hyaluronic acid components may be used in combination.

[0117] Hyaluronic acid is the predominant glycosaminoglycan found in the skin. Fibroblasts therefore predominantly synthesize collagen, non-collagen matrix glycoproteins (fibronectin, laminin), proteoglycans, and elastin. Keratinocytes predominantly synthesize sulfated glycosaminoglycans and hyaluronic acid. Hyaluronic acid is also called hyaluronan.

[0118] Hyaluronic acid exists in free state in the epidermis and dermis, and is responsible for the turgor of the skin.This polysaccharide can actually hold a large volume of water, up to 1000 times its mass.In this sense, hyaluronic acid plays an important role in increasing the amount of water bound in tissue, and also in the mechanical properties and wrinkle formation of the skin.

[0119] Hyaluronic acid can be represented by the following chemical formula:

[0120] [ka]

[0121] In the context of the present invention, the term "hyaluronic acid" particularly encompasses the basic unit of hyaluronic acid of the formula:

[0122] [ka]

[0123] This is the smallest fraction of hyaluronic acid containing the disaccharide dimer, i.e., D-glucuronic acid and N-acetylglucosamine.

[0124] The hyaluronic acid derivative may be selected from the group consisting of hydrolyzed hyaluronic acid, acetylated hyaluronic acid, cationic hyaluronic acid, and mixtures thereof.

[0125] Cationic hyaluronic acid contains at least one cationic moiety. The cationic moiety is -N + The cationic moiety may be a trialkylammonium group such as (CH3)3. The cationic moiety may contain at least one hydroxyl group. An example of a cationic group is -CH2-CH(OH)-CH2-N + (CH3)3 is an example.

[0126] An example of a cationic hyaluronic acid is hydroxypropyltrimonium hyaluronate.

[0127] Hyaluronic acid salts or hyaluronic acid derivative salts include alkali metal salts such as sodium salts and potassium salts, alkaline earth metal salts such as magnesium salts, ammonium salts, and mixtures thereof.

[0128] The molecular weight of the hyaluronic acid component is not limited. The molecular weight of the hyaluronic acid component may be 5 kDa or more, preferably 20 kDa or more, and more preferably 100 kDa or more. The molecular weight of the hyaluronic acid component may be 20 MDa or less, preferably 10 MDa or less, and more preferably 2,000 kDa or less. Therefore, the molecular weight of the hyaluronic acid component may be 5 kDa to 20 MDa, preferably 20 kDa to 10 MDa, and more preferably 100 kDa to 2,000 kDa.

[0129] Unless otherwise defined in the description, "molecular weight" may mean number average molecular weight.

[0130] The hyaluronic acid component may in particular be hyaluronic acid supplied by Hyactive under the trade name CPN (MW: 10-150 kDa), by Soliance under the trade name Cristalhyal (MW: 1-1.4 MDa), by Bioland under the name Nutra HA (MW: 820 000 Da), by Bioland under the name Nutra AF (MW: 69 000 Da) and by Bioland under the name Oligo HA (MW: 6100 Da).

[0131] A single hyaluronic acid component having a single molecular weight or a combination of two or more hyaluronic acid components having different molecular weights can be used.

[0132] The amount of the (d) hyaluronic acid component in the composition according to the present invention may be 0.001% by mass or more, preferably 0.01% by mass or more, more preferably 0.1% by mass or more, relative to the total mass of the composition.

[0133] The amount of the (d) hyaluronic acid component in the composition according to the present invention may be 5% by mass or less, preferably 4% by mass or less, more preferably 3% by mass or less, relative to the total mass of the composition.

[0134] Therefore, the amount of the (d) hyaluronic acid component in the composition according to the present invention may be within the range of 0.001% to 5% by mass, preferably 0.01% to 4% by mass, and more preferably 0.1% to 3% by mass, relative to the total mass of the composition.

[0135] [Polyols with 5 or more carbon atoms] The composition according to the present invention comprises (e) at least one polyol having 5 or more carbon atoms. A single type of such polyol may be used, or two or more different types of such polyols may be used in combination.

[0136] The polyol having 5 or more carbon atoms is a diol having 5 or more carbon atoms, preferably a C5-C 10It may be selected from diols, more preferably pentylene glycol, hexylene glycol, and mixtures thereof.

[0137] Pentylene glycol includes its isomers. Thus, pentylene glycol can be 1,2-pentylene glycol, 1,3-pentylene glycol, 1,4-pentylene glycol, 1,5-pentylene glycol, 2,3-pentylene glycol, and 2,4-pentylene glycol. 1,2-pentylene glycol may be preferred.

[0138] Hexylene glycol includes its isomers. Thus, hexylene glycol can be 1,2-hexylene glycol, 1,3-hexylene glycol, 1,4-hexylene glycol, 1,5-hexylene glycol, 1,6-hexylene glycol, 2,3-hexylene glycol, 2,4-hexylene glycol, 2,5-hexylene glycol, and 2-methyl-2,4-pentanediol. 2-Methyl-2,4-pentanediol may be preferred.

[0139] The amount of (e) polyol having 5 or more carbon atoms in the composition according to the present invention may be 0.01% by mass or more, preferably 0.1% by mass or more, and more preferably 1% by mass or more, relative to the total mass of the composition.

[0140] On the other hand, the amount of (e) polyol having 5 or more carbon atoms in the composition according to the present invention may be 7% by mass or less, preferably 6% by mass or less, and more preferably 5% by mass or less, relative to the total mass of the composition.

[0141] Therefore, the amount of (e) polyol having 5 or more carbon atoms in the composition according to the present invention may be in the range of 0.01% by mass to 7% by mass, preferably 0.1% by mass to 6% by mass, and more preferably 1% by mass to 5% by mass, relative to the total mass of the composition.

[0142] [water] The composition according to the present invention comprises (f) water.

[0143] The amount of (f) water in the composition according to the present invention may be 50% by mass or more, preferably 60% by mass or more, and more preferably 70% by mass or more, based on the total mass of the composition.

[0144] On the other hand, the amount of (f) water in the composition according to the present invention may be 95% by mass or less, preferably 90% by mass or less, and more preferably 85% by mass or less, based on the total mass of the composition.

[0145] The amount of (f) water in the composition according to the present invention may be within the range of 50% by mass to 95% by mass, preferably 60% by mass to 90% by mass, and more preferably 70% by mass to 85% by mass, relative to the total mass of the composition.

[0146] [Quantitative requirements] The total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester in the composition according to the present invention is 0.01% by mass to 5% by mass, preferably 0.02% by mass to 4.5% by mass, and more preferably 1% by mass to 4% by mass, relative to the total mass of the composition.

[0147] The mass ratio of (a) the amount of oil to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) in the composition according to the present invention is less than 0.3, preferably less than 0.2, and more preferably less than 0.1.

[0148] The composition according to the present invention may be free of any (a) oil, in which case the (b) first polyglyceryl fatty acid ester and the (c) second polyglyceryl fatty acid ester may form micelles, which may form a dispersed phase in the composition according to the present invention and which are free of (a) oil.

[0149] The compositions according to the present invention may also contain (a) oil. In this case, (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester may form micelles, which may form a dispersed phase in the compositions according to the present invention and contain (a) oil. Micelles containing (a) oil can be thought of as "oil" droplets.

[0150] The mass ratio of (amount of (c) second polyglyceryl fatty acid ester) / (amount of (b) first polyglyceryl fatty acid ester) in the composition according to the present invention is greater than 0.01 and less than 0.2, preferably greater than 0.02 and less than 0.19, and more preferably greater than 0.03 and less than 0.18.

[0151] The mass ratio of (e) the amount of polyol having 5 or more carbon atoms to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) in the composition according to the present invention is greater than 0.1 and less than 5, preferably greater than 0.15 and less than 4.5, and more preferably greater than 0.2 and less than 4.0.

[0152] [More polyols] The composition of the present invention may contain at least one additional polyol other than (e) the polyol having 5 or more carbon atoms. A single type of such additional polyol may be used, or two or more different types of such additional polyols may be used in combination.

[0153] The term "polyol" as used herein means an alcohol having two or more hydroxy groups and does not include sugars or their derivatives. Sugar derivatives include sugar alcohols obtained by reducing one or more carbonyl groups of a sugar, and sugars or sugar alcohols in which the hydrogen atom in one or more of their hydroxy groups has been replaced with at least one substituent, such as an alkyl group, a hydroxyalkyl group, an alkoxy group, an acyl group, or a carbonyl group.

[0154] The polyol may be a C2 to C4 polyol, preferably a C2 to C4 polyol containing at least two hydroxy groups, preferably from 2 to 5 hydroxy groups.

[0155] The polyol may be a natural or synthetic polyol. The polyol may have a linear, branched, or cyclic molecular structure.

[0156] The polyol may be selected from glycerin and its derivatives, and glycol and its derivatives. The polyol may be selected from the group consisting of glycerin, ethylene glycol, propylene glycol, and butylene glycol.

[0157] The amount of further polyol in the composition according to the invention may be up to 20% by weight, preferably up to 15% by weight, more preferably up to 10% by weight relative to the total weight of the composition.

[0158] The amount of further polyol in the composition according to the invention may be from 1% to 20% by weight, preferably from 3% to 15% by weight, more preferably from 5% to 10% by weight, relative to the total weight of the composition.

[0159] It may be preferred that compositions according to the present invention are butylene glycol-free.

[0160] [Other ingredients] The composition according to the present invention may contain one or more monohydric alcohols that are in liquid form at room temperature (25°C), such as linear or branched monohydric alcohols containing 1 to 6 carbon atoms, such as ethanol, propanol, butanol, isopropanol, isobutanol, pentanol, and hexanol.

[0161] The amount of monohydric alcohol in the composition according to the invention may be 0.01% by weight or more, preferably 0.1% by weight or more, more preferably 1% by weight or more, relative to the total weight of the composition.

[0162] On the other hand, the amount of monohydric alcohol in the composition according to the present invention may be 15% by weight or less, preferably 10% by weight or less, more preferably 5% by weight or less, relative to the total weight of the composition.

[0163] Therefore, the amount of monohydric alcohol in the composition according to the present invention may be in the range of 0.01% by mass to 15% by mass, preferably 0.1% by mass to 10% by mass, and more preferably 1% by mass to 5% by mass, relative to the total mass of the composition.

[0164] The compositions according to the invention may also comprise, apart from the ingredients explained above, various adjuvants conventionally used in cosmetic and dermatological compositions, such as thickeners, anionic, nonionic, cationic, and amphoteric or zwitterionic polymers, anionic, further nonionic, cationic, and amphoteric surfactants, antioxidants, colorants, chelating agents, sequestering agents, fragrances, dispersing agents, conditioning agents, film-forming agents, preservatives, co-preservatives, and mixtures thereof.

[0165] In one embodiment, the composition according to the present invention does not contain polyglyceryl fatty acid esters containing 5 or more glycerol units, such as PG5 laurate. The term "free" here means that the composition according to the present invention may contain a limited amount of polyglyceryl fatty acid esters containing 5 or more glycerol units. However, it is preferred that the amount of polyglyceryl fatty acid esters containing 5 or more glycerol units is limited to less than 1% by weight, more preferably less than 0.1% by weight, and even more preferably less than 0.01% by weight, based on the total weight of the composition. Most preferably, the composition according to the present invention does not contain polyglyceryl fatty acid esters containing 5 or more glycerol units.

[0166] In another embodiment, the composition according to the present invention does not contain a polyoxyethylene-based nonionic surfactant. The term "free" here means that the composition according to the present invention may contain a limited amount of a polyoxyethylene-based nonionic surfactant. However, it is preferred that the amount of the polyoxyethylene-based nonionic surfactant is limited to less than 1% by weight, more preferably less than 0.1% by weight, and even more preferably less than 0.01% by weight, based on the total weight of the composition. Most preferably, the composition according to the present invention does not contain a polyoxyethylene-based nonionic surfactant.

[0167] (preparation) The composition according to the present invention can be prepared by mixing the essential ingredients described above and, if necessary, the optional ingredients described above.

[0168] The method and means for mixing the above essential components and optional components are not limited. Any conventional method and means can be used to mix the above essential components and optional components to prepare the composition according to the present invention.

[0169] The composition according to the present invention can be prepared without using a large amount of energy, such as that required by a homogenizer. Therefore, the composition according to the present invention can be prepared by using a small amount of energy, such as by gently stirring the components of the composition together. Therefore, the composition according to the present invention is environmentally friendly in view of its preparation method.

[0170] [form] The composition according to the present invention comprises a continuous phase and a dispersed phase. The dispersed phase is dispersed in the continuous phase. The dispersed phase may therefore be in the form of particles.

[0171] The continuous phase can include (f) water. The dispersed phase can include at least (b) a first polyglyceryl fatty acid ester and (c) a second polyglyceryl fatty acid ester. When the composition includes (a) oil, the dispersed phase can also include (a) oil. When the dispersed phase includes (a) oil, the dispersed phase can be recognized as oil droplets. When the dispersed phase does not include (a) oil, the dispersed phase includes (b) a first polyglyceryl fatty acid ester and (c) a second polyglyceryl fatty acid ester, and the two polyglyceryl fatty acid esters can form micelles.

[0172] The size of the dispersed phase is 300 nm or less, preferably 200 nm or less, and more preferably 100 nm or less. The size can be measured as a volume-based average size. The size can be measured by dynamic light scattering, for example, using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.). The minimum size of the dispersed phase is not limited, but may be 1 nm or more, 5 nm or more, or 10 nm or more.

[0173] The composition according to the invention may be in the form of a nano- or microemulsion when the composition comprises (a).

[0174] "Microemulsion" can be defined in two ways, that is, broadly and narrowly. In other words, there is one case ("narrowly defined microemulsion") where microemulsion refers to a thermodynamically stable isotropic single liquid phase, which contains a three-component system consisting of an oil component, an aqueous component and a surfactant. There is also a second case ("broadly defined microemulsion") where microemulsion further includes emulsions that have a transparent or slightly translucent appearance due to smaller particle size among typical thermodynamically unstable emulsion systems (Satoshi Tomomasa et al., Oil Chemistry, Vol. 37, No. 11 (1988), pp. 48-53). As used herein, "microemulsion" refers to "narrowly defined microemulsion", that is, a thermodynamically stable isotropic single liquid phase.

[0175] Microemulsions refer to any one of the following types of microemulsions: O / W (oil-in-water) microemulsions in which oil is solubilized by micelles; W / O (water-in-oil) microemulsions in which water is solubilized by reverse micelles; or bicontinuous microemulsions in which the number of surfactant molecule associations is infinite, resulting in both the aqueous and oily phases having a continuous structure.

[0176] Microemulsions may have a dispersed phase with a particle size of 100 nm or less, preferably 80 nm or less, more preferably 60 nm or less, as measured by laser particle size analysis.

[0177] By "nanoemulsion" is meant herein an emulsion characterized by a dispersed phase having a size of less than 350 nm, which is stabilized at the dispersed / continuous phase interface by a crown of nonionic surfactants (b) and (c), which can optionally form a lamellar liquid crystal phase. In the absence of specific opacifiers, the transparency of nanoemulsions results from the small size of the dispersed phase, which is obtained by the use of mechanical energy.

[0178] Nanoemulsions can be distinguished from microemulsions by their structure. Specifically, microemulsions are thermodynamically stable dispersions formed, for example, from micelles formed by components (b) and (c) and expanded by component (a). Furthermore, microemulsions do not require substantial mechanical energy to prepare.

[0179] The nanoemulsion may have a dispersed phase with a particle size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less, as measured by laser particle size analysis.

[0180] The compositions according to the invention are preferably in the form of an O / W emulsion, comprising an oily phase dispersed in a continuous aqueous phase. The dispersed oily phase can be oil droplets in the aqueous phase.

[0181] An O / W type constitution or structure consists of an oil phase dispersed in an aqueous phase, and therefore has an aqueous phase on the outside. Therefore, when the composition according to the present invention has an O / W type constitution or structure, it can provide a pleasant sensation when used due to the immediate fresh feeling that the aqueous phase can provide.

[0182] The particle size of the (a) oil may be 100 nm or less, preferably 75 nm or less, and more preferably 50 nm or less. The particle size can be measured by dynamic light scattering. The particle size measurement can be performed, for example, by a particle size analyzer ELSZ-2000 series, commercially available from Otsuka Electronics Co., Ltd.

[0183] The particle size may be the volume average particle diameter or the number average particle diameter, preferably the volume average particle diameter.

[0184] Compositions according to the present invention may be transparent or slightly translucent.

[0185] Clarity can be measured by measuring turbidity (for example, turbidity can be measured using a 2100Q (commercially available from Hach Company) with a round cell (25 mm diameter and 60 mm height) and a tungsten filament bulb capable of emitting visible light (between 400 and 800 nm, preferably 400-500 nm). Measurements can be performed on the undiluted composition. A blank can be determined using distilled water.

[0186] The composition according to the present invention may have a turbidity of 50 NTU or less, preferably 30 NTU or less, more preferably 10 NTU or less.

[0187] [Method and Use] The composition according to the invention is preferably a cosmetic or dermatological composition, preferably a cosmetic composition, more preferably a cosmetic composition for keratinous materials such as the skin.

[0188] The compositions according to the invention can be used in non-therapeutic methods, such as cosmetic methods, for treating keratinous materials such as the skin, hair, mucous membranes, nails, eyelashes, eyebrows and / or scalp by applying them to the keratinous materials.

[0189] The present invention therefore also relates to a cosmetic method for treating keratinous materials, comprising the step of applying to the keratinous materials a composition according to the invention.

[0190] The present invention may also relate to the use of the compositions according to the invention as or in cosmetics, such as care products, cleansing products, make-up products, make-up removal products, etc. for the skin of the body and / or face, and / or mucous membranes, and / or the scalp, and / or the hair, and / or the nails, and / or the eyelashes, and / or the eyebrows.

[0191] In other words, the composition according to the present invention can be used as a cosmetic by itself. Alternatively, the composition according to the present invention can be used as one component of a cosmetic. For example, the composition according to the present invention can be used in addition to or in combination with any other components to form a cosmetic.

[0192] The care product can be a lotion, a cream, a hair tonic, a hair conditioner, a sunscreen, etc. The cleansing product can be a shampoo, a face wash, a hand wash, etc. The makeup product can be a foundation, a mascara, a lipstick, a lip gloss, a blush, an eye shadow, a nail polish, etc. The makeup removal product can be a makeup cleanser, etc.

[0193] Since the composition according to the invention comprises at least one hyaluronic acid or a salt thereof, the composition according to the invention can preferably be used to moisturize keratinous materials such as the skin.

[0194] Another aspect of the present invention is a method for producing a semiconductor device comprising: For the preparation of a composition comprising a continuous phase and a dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less, (e) at least one polyol having 5 or more carbon atoms The use of the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition; the mass ratio of (a) the amount of oil to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is less than 0.3; the mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester) / ((b) the amount of the first polyglyceryl fatty acid ester) is greater than 0.01 and less than 0.2; The mass ratio of (e) the amount of polyol) / (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is greater than 0.1 and less than 5. Under the condition that, The composition comprises: (a) at least one optional oil; (b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, and more preferably greater than 13.0; (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, and more preferably less than 9.0; (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof; and (f) water The present invention may relate to the use of

[0195] Another aspect of the present invention is also a method for preparing a composition comprising a continuous phase and a dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less, comprising the steps of: the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition; the mass ratio of (a) the amount of oil to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is less than 0.3; the mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester) / ((b) the amount of the first polyglyceryl fatty acid ester) is greater than 0.01 and less than 0.2; The mass ratio of (e) the amount of polyol) / (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is greater than 0.1 and less than 5. Under the condition that, (a) at least one optional oil; (b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, and more preferably greater than 13.0; (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, and more preferably less than 9.0; (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof; (e) at least one polyol having 5 or more carbon atoms, and (f) water The present invention may also relate to a method comprising the step of mixing

[0196] The mixing step is preferably carried out by a so-called low-energy process that does not use a special mechanical agitator such as a homogenizer that uses a large amount of energy. The low-energy process can be carried out by simply gently stirring the components (a) to (f).

[0197] The composition in the uses and methods according to the present invention is preferably in the form of an O / W nano- or micro-emulsion when the composition comprises (a) an oil.

[0198] The present invention also provides (e) at least one polyol having 5 or more carbon atoms The use of the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition; the mass ratio of (a) the amount of oil to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is less than 0.3; the mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester) / ((b) the amount of the first polyglyceryl fatty acid ester) is greater than 0.01 and less than 0.2; The mass ratio of (e) the amount of polyol) / (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is greater than 0.1 and less than 5. Under the condition that, (a) at least one oil; (b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, and more preferably greater than 13.0; (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, and more preferably less than 9.0; (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof; and (f) water In an O / W type emulsion comprising (a) to make the oil droplets have a particle size of 300 nm or less, preferably 200 nm or less, and more preferably 100 nm or less; It may also relate to use.

[0199] The present invention also provides (a) at least one oil; (b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, and more preferably greater than 13.0; (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, and more preferably less than 9.0; (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof; and (f) water A method for making oil droplets in an O / W type nano- or micro-emulsion containing the above-mentioned component have a particle size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less, comprising: (e) at least one polyol having 5 or more carbon atoms; The present invention also relates to a method comprising adding the composition to an O / W nano- or micro-emulsion or using the composition in an O / W nano- or micro-emulsion.

[0200] The above descriptions of components (a) to (f) and optional components of the compositions according to the invention are applicable to the components of the uses and methods according to the invention. The descriptions of the preparation and forms of the compositions according to the invention are also applicable to the preparation and forms of the compositions described in the uses and methods above. [Example]

[0201] The present invention will now be described in more detail by way of examples, which should not be construed as limiting the scope of the present invention.

[0202] (Example 1 and Comparative Examples 1 to 3) The following compositions shown in Table 1 according to Example 1 and Comparative Examples 1 to 3 were prepared by mixing the components shown in Table 1. All numerical values ​​for the amounts of components shown in Table 1 are based on "mass %" of the raw materials.

[0203] The compositions according to Example 1 and Comparative Examples 1 to 3 were in the form of O / W emulsions.

[0204] [Table 1]

[0205] [evaluation] (Turbidity) The turbidity of the compositions according to Example 1 and Comparative Example 2 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

[0206] The results are shown as "NTU" in Table 1. The lower the NTU value, the more transparent the composition.

[0207] The composition according to Example 1 was clear or slightly translucent.

[0208] The turbidity of the compositions according to Comparative Examples 1 and 3 was not measured because the compositions were clearly opaque (not clear or slightly translucent).

[0209] (Droplet diameter) The size of the dispersed phase in the compositions of Example 1 and Comparative Example 2 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

[0210] The size of the dispersed phase of the compositions according to Comparative Examples 1 and 3 was not measured because the compositions were clearly opaque.

[0211] Example 1 shows that the use of polyols having 5 or more carbon atoms can provide a clear composition, even when the composition contains hyaluronic acid or a salt thereof.

[0212] Comparative Example 1 shows that the use of a polyol having less than 5 carbon atoms does not provide a clear composition when the composition includes hyaluronic acid or a salt thereof.

[0213] Comparative Example 2 corresponds to the formulation according to Example 1 disclosed in WO 2020 / 110716.

[0214] Comparative Example 3 shows that adding hyaluronic acid or a salt thereof to the formulation according to Example 1 disclosed in WO 2020 / 110716 does not provide a clear composition.

[0215] (Examples 2 to 5 and Comparative Example 4) The following compositions shown in Table 2 according to Examples 2 to 5 and Comparative Example 4 were prepared by mixing the components shown in Table 2. All numerical values ​​for the amounts of components shown in Table 2 are based on "mass %" of the raw materials.

[0216] The compositions according to Examples 2 to 5 and Comparative Example 4 were in the form of O / W emulsions.

[0217] [Table 2]

[0218] [evaluation] (Turbidity) The turbidity of the compositions according to Examples 2 to 5 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

[0219] The results are shown as "NTU" in Table 2. The lower the NTU value, the more transparent the composition.

[0220] The compositions according to Examples 2 to 5 were transparent or slightly translucent.

[0221] The NTU value of the composition according to Comparative Example 4 was not tested because the composition was opaque.

[0222] (Droplet diameter) The size of the dispersed phase in the compositions of Examples 2 to 5 and Comparative Example 4 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

[0223] The results are shown in Table 2.

[0224] The droplet size of the dispersed phase in the composition according to Comparative Example 4 was not tested because the composition was opaque.

[0225] Examples 2 to 5 show that the total amount of the first polyglyceryl fatty acid ester having an HLB value greater than 11.0 and the second polyglyceryl fatty acid ester having an HLB value less than 11.0 in the composition should be 0.01% by mass to 5% by mass, based on the total mass of the composition.

[0226] Comparative Example 4 shows that when the total amount of the first and second polyglyceryl fatty acid esters in the composition is more than 5% by weight relative to the total weight of the composition, the composition cannot be made transparent or slightly translucent.

[0227] (Examples 6 to 7 and Comparative Example 5) The following compositions shown in Table 3 according to Examples 6-7 and Comparative Example 5 were prepared by mixing the components shown in Table 3. All numerical values ​​for the amounts of components shown in Table 3 are based on "mass %" of the raw materials.

[0228] The composition according to Example 6 was a composition containing micelles formed by PG-4 caprate and PG-2 oleate.

[0229] The compositions according to Example 7 and Comparative Example 5 were in the form of O / W emulsions.

[0230] [Table 3]

[0231] [evaluation] (Turbidity) The turbidity of the compositions according to Examples 6-7 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

[0232] The results are shown as "NTU" in Table 3. The lower the NTU value, the more transparent the composition.

[0233] The compositions according to Examples 6 and 7 were clear or slightly translucent.

[0234] The NTU value of the composition according to Comparative Example 5 was not tested because the composition was opaque.

[0235] (Droplet diameter) The size of the dispersed phase in the compositions of Examples 6 and 7 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

[0236] The results are shown in Table 3.

[0237] The droplet size of the composition according to Example 6 refers to the average size of the oil-free micelles in the composition.

[0238] The droplet size of the composition according to Example 7 refers to the average size of the oil droplets, which can be thought of as micelles containing the oil, in the composition.

[0239] The droplet size of the dispersed phase in the composition according to Comparative Example 5 was not tested because the composition was opaque.

[0240] Examples 6 and 7 show that the mass ratio of (amount of oil) / (total amount of the first polyglyceryl fatty acid ester having an HLB value greater than 11.0 and the second polyglyceryl fatty acid ester having an HLB value less than 11.0) in the composition should be less than 0.3.

[0241] Comparative Example 5 shows that when the mass ratio of (amount of oil) / (total amount of the first polyglyceryl fatty acid ester having an HLB value greater than 11.0 and the second polyglyceryl fatty acid ester having an HLB value less than 11.0) in the composition is 0.3 or more, the composition cannot be made transparent or slightly translucent.

[0242] (Examples 8 to 9 and Comparative Examples 6 to 7) The following compositions shown in Table 4 according to Examples 8-9 and Comparative Examples 6-7 were prepared by mixing the components shown in Table 4. All numerical values ​​for the amounts of components shown in Table 4 are based on "mass %" of the raw materials.

[0243] The compositions according to Examples 8 to 9 and Comparative Examples 6 to 7 were in the form of O / W emulsions.

[0244] [Table 4]

[0245] [evaluation] (Turbidity) The turbidity of the compositions according to Examples 8-9 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

[0246] The results are shown as "NTU" in Table 4. The lower the NTU value, the more transparent the composition.

[0247] The compositions according to Examples 8 and 9 were clear or slightly translucent.

[0248] The NTU values ​​of the compositions according to Comparative Examples 6-7 were not tested because the compositions were opaque.

[0249] (Droplet diameter) The size of the dispersed phase in the compositions of Examples 8 and 9 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

[0250] The results are shown in Table 4.

[0251] The droplet size of the dispersed phase in the compositions according to Comparative Examples 6-7 was not tested because the compositions were opaque.

[0252] Examples 8 and 9 show that the mass ratio of (amount of second polyglyceryl fatty acid ester having an HLB value less than 11.0) / (amount of first polyglyceryl fatty acid ester having an HLB value greater than 11.0) in the composition should be greater than 0.01 and less than 0.2.

[0253] Comparative Examples 6 and 7 show that when the mass ratio of (the amount of the second polyglyceryl fatty acid ester having an HLB value less than 11.0) / (the amount of the first polyglyceryl fatty acid ester having an HLB value greater than 11.0) in the composition is 0.01 or less or 0.2 or more, the composition cannot be made transparent or slightly translucent.

[0254] (Examples 10 to 11 and Comparative Examples 8 to 9) The following compositions shown in Table 5 according to Examples 10-11 and Comparative Examples 8-9 were prepared by mixing the components shown in Table 5. All numerical values ​​for the amounts of components shown in Table 5 are based on "mass %" of the raw materials.

[0255] The compositions according to Examples 10 to 11 and Comparative Examples 8 to 9 were in the form of O / W emulsions.

[0256] [Table 5]

[0257] [evaluation] (Turbidity) The turbidity of the compositions according to Examples 10-11 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

[0258] The results are shown as "NTU" in Table 5. The lower the NTU value, the more transparent the composition.

[0259] The compositions according to Examples 10 and 11 were clear or slightly translucent.

[0260] The NTU values ​​of the compositions according to Comparative Examples 8-9 were not tested because the compositions were opaque.

[0261] (Droplet diameter) The size of the dispersed phase in the compositions of Examples 10 and 11 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

[0262] The results are shown in Table 5.

[0263] The droplet size of the dispersed phase in the compositions according to Comparative Examples 8 and 9 was not tested because the compositions were opaque.

[0264] Examples 10 and 11 show that the mass ratio of (amount of polyol having 5 or more carbon atoms) / (total amount of first polyglyceryl fatty acid ester having an HLB value greater than 11.0 and second polyglyceryl fatty acid ester having an HLB value less than 11.0) in the composition should be greater than 0.1 and less than 5.

[0265] Comparative Examples 8 and 9 show that when the mass ratio of (amount of polyol having 5 or more carbon atoms) / (total amount of first polyglyceryl fatty acid ester having an HLB value greater than 11.0 and second polyglyceryl fatty acid ester having an HLB value less than 11.0) in the composition is 0.1 or less or 5 or more, the composition cannot be made transparent or slightly translucent.

[0266] Examples 12 to 15 The following compositions shown in Table 6 according to Examples 12-15 were prepared by mixing the ingredients shown in Table 6. All numerical values ​​for the amounts of ingredients shown in Table 6 are based on "mass %" of the ingredients.

[0267] The compositions according to Examples 12 to 15 were in the form of O / W emulsions.

[0268] [Table 6]

[0269] [evaluation] (Turbidity) The turbidity of the compositions according to Examples 12 to 15 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

[0270] The results are shown as "NTU" in Table 6. The lower the NTU value, the more transparent the composition.

[0271] The compositions according to Examples 12 to 14 were transparent or slightly translucent.

[0272] (Droplet diameter) The size of the dispersed phase in the compositions of Examples 12 to 15 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

[0273] The results are shown in Table 6.

[0274] Examples 12 to 15 show that compositions according to the present invention can be transparent or slightly translucent even when they contain various amounts of hyaluronic acid or a salt thereof, regardless of the molecular weight of the hyaluronic acid.

[0275] (Examples 16 to 18 and Comparative Example 10) The following compositions shown in Table 7 according to Examples 16-18 and Comparative Example 10 were prepared by mixing the components shown in Table 7. All numerical values ​​for the amounts of components shown in Table 7 are based on "mass %" of the raw materials.

[0276] The compositions according to Examples 16 to 18 and Comparative Example 10 were in the form of O / W emulsions.

[0277] [Table 7]

[0278] [evaluation] (Turbidity) The turbidity of the compositions according to Examples 16-18 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

[0279] The results are shown as "NTU" in Table 7. The lower the NTU value, the more transparent the composition.

[0280] The compositions according to Examples 16 to 18 were transparent or slightly translucent.

[0281] The NTU value of the composition according to Comparative Example 10 was not tested because the composition was opaque.

[0282] (Droplet diameter) The size of the dispersed phase in the compositions of Examples 16 to 18 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

[0283] The results are shown in Table 7.

[0284] The droplet size of the dispersed phase in the composition according to Comparative Example 10 was not tested because the composition was opaque.

[0285] Example 16 shows that the type of polyglyceryl fatty acid ester is not limiting.

[0286] Example 17 shows that the type of polyol having 5 or more carbon atoms is not limiting.

[0287] Example 18 shows that the type of oil is not limiting.

[0288] Comparative Example 10 shows that when a polyol having less than 5 carbon atoms is used in the composition, the composition cannot be made clear or slightly translucent.

[0289] (Examples 19 to 25) The following compositions shown in Table 8 according to Examples 19-25 were prepared by mixing the ingredients shown in Table 8. All numerical values ​​for the amounts of ingredients shown in Table 8 are based on "mass %" of the ingredients.

[0290] The compositions according to Examples 19 to 25 were in the form of O / W emulsions.

[0291] [Table 8]

[0292] [evaluation] (Turbidity) The turbidity of the compositions according to Examples 19 to 25 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

[0293] The results are shown as "NTU" in Table 8. The lower the NTU value, the more transparent the composition.

[0294] The compositions according to Examples 19 to 25 were transparent or slightly translucent.

[0295] (Droplet diameter) The size of the dispersed phase in the compositions of Examples 19 to 25 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

[0296] The results are shown in Table 8.

[0297] Examples 19 to 25 demonstrate that the type of hyaluronic acid or its salt is not limited.

Claims

1. (a) at least one optional oil; (b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0; (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0; (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof; (e) at least one polyol having 5 or more carbon atoms, and (f) water A composition comprising: the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass, based on the total amount of the composition; the mass ratio of (a) the amount of oil to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is less than 0.3; the mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester) / ((b) the amount of the first polyglyceryl fatty acid ester) is greater than 0.01 and less than 0.2; the mass ratio of (e) the amount of polyol having 5 or more carbon atoms to (the total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester) is greater than 0.1 and less than 5; The composition comprises a continuous phase and a dispersed phase, the dispersed phase having a size of 300 nm or less. composition.

2. The composition of claim 1 , wherein the (a) oil is selected from polar oils.

3. 3. The composition according to claim 1, wherein the amount of (a) oil in the composition is less than 0.7% by weight, based on the total weight of the composition.

4. 4. The composition of claim 1, wherein the first polyglyceryl fatty acid ester comprises from 2 to 4 glycerol units.

5. 5. The composition of claim 1, wherein the fatty acid moiety of the first polyglyceryl fatty acid ester comprises 12 or fewer carbon atoms.

6. The composition according to any one of claims 1 to 5, wherein the amount of (b) the first polyglyceryl fatty acid ester in the composition is 0.01% by weight to 5% by weight, relative to the total weight of the composition.

7. 7. The composition of claim 1, wherein (c) the second polyglyceryl fatty acid ester comprises 2 to 4 glycerol units.

8. 8. The composition of claim 1, wherein the fatty acid portion of the second polyglyceryl fatty acid ester comprises 14 or more carbon atoms.

9. The composition according to any one of claims 1 to 8, wherein the amount of (c) the second polyglyceryl fatty acid ester in the composition is 0.001% by weight to 0.5% by weight, relative to the total weight of the composition.

10. 10. The composition of claim 1, wherein the (d) hyaluronic acid component is selected from hyaluronic acid, hydrolyzed hyaluronic acid, acetylated hyaluronic acid, cationic hyaluronic acid, salts thereof, and mixtures thereof.

11. The composition according to any one of claims 1 to 10, wherein the amount of the (d) hyaluronic acid component in the composition is 0.001% by weight to 5% by weight, relative to the total weight of the composition.

12. 12. The composition of claim 1, wherein (e) the polyol having 5 or more carbon atoms is selected from a diol having 5 or more carbon atoms.

13. 13. The composition according to any one of claims 1 to 12, wherein the amount of (e) polyol having 5 or more carbon atoms in the composition is in the range of 0.01% by weight to 7% by weight, relative to the total weight of the composition.

14. 14. The composition according to claim 1, comprising (a) an oil and in the form of an O / W emulsion.

15. A cosmetic method for treating keratinous materials, comprising the step of applying a composition according to any one of claims 1 to 14 to the keratinous materials.

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