Light diffusion device and medical device using the same

Abstract

To provide a light diffusion device that can irradiate a plurality of parts inside the human body with laser beams in a state that the tip of a light transmission cable is inserted into the human body.SOLUTION: A light diffusion device includes: a light transmission cable 20 having a plurality of cores 22; and a light refraction part 30 for refracting respective laser beams L emitted from the plurality of cores 22 in the tip of the light transmission cable 20 so as to make the directions of radiation different from each other. With this, laser beams L can be irradiated in a plurality of directions in a state that the tip of the light transmission cable 20 is inserted into the human body, and thus, it is possible to change a part to be irradiated with laser beams L in the human body without withdrawing the light transmission cable 20 from the human body so as to shorten a time required for light immune therapy.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to a light diffusing device used in the medical field and a medical instrument using the same. [Background technology]

[0002] A known conventional light diffusion device includes an optical transmission cable having an optical transmission path through which light emitted from a light source is transmitted, and a lens provided at the tip of the optical transmission cable, and irradiates the light emitted from the optical transmission cable in a predetermined direction through the lens (see, for example, Patent Document 1).

[0003] Light diffusion devices are used in photoimmunotherapy, a cancer treatment method, by inserting the tip of an optical transmission cable into the human body and irradiating laser light onto a drug that has been administered to the body and reached cancer cells.Light diffusion devices often use optical fiber as the optical transmission cable, and include cylindrical diffusers that emit light from the outer surface of the optical fiber and frontal diffusers that emit light from the end face of the tip of the optical fiber. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Special Publication No. 2003-528347 Summary of the Invention [Problem to be solved by the invention]

[0005] In photoimmunotherapy, it is necessary to irradiate multiple locations within the human body with laser light while the distal end of the optical transmission cable of the light diffusion device is inserted into the human body or positioned near the surface of a tumor. However, conventional light diffusion devices, particularly frontal diffusers, irradiate light emitted from the optical transmission cable only in a predetermined direction. Therefore, when changing the location of laser light irradiation while the device is inserted into the human body or positioned near the surface of a tumor, it is necessary to bend the optical transmission cable as necessary to adjust the irradiation direction of the laser light and reinsert it into the body, which may result in a long photoimmunotherapy time.

[0006] The object of the present invention is to provide an optical diffusion device and a medical device using the same that can irradiate laser light to multiple locations inside the human body when the tip of an optical transmission cable is inserted into the human body or positioned near the surface of a tumor. [Means for solving the problem]

[0007] The light diffusion device of the present invention comprises an optical transmission cable having a plurality of optical transmission paths through which light emitted from a light source is transmitted, and an optical refraction section provided at the tip of the optical transmission cable, which refracts each of the lights emitted from the plurality of optical transmission paths so that the irradiation directions are different from each other.

[0008] In addition, the light diffusion device of the present invention is a lens in which the light refraction portion has an incident surface into which light emitted from the plurality of light transmission paths is incident, which is formed as a curved surface that protrudes toward the optical transmission cable, and an exit surface from which the incident light exits, which is formed as a curved surface that protrudes in the direction of light emission.

[0009] In addition, in the light diffusion device of the present invention, the optical transmission cable has a multi-core optical fiber in which a plurality of cores serving as the optical transmission paths are provided in one clad, and the direction of light irradiation is switched by switching the core that transmits light among the plurality of cores.

[0010] The light diffusing device according to the present invention further comprises an auxiliary light refracting section for refracting light between the tip of the optical transmission cable and the light refracting section.

[0011] In addition, in the light diffusion device of the present invention, the optical transmission cable has a plurality of single-core optical fibers, each having a core as the optical transmission path provided in a clad, and the direction of light irradiation is switched by switching the single-core optical fiber that transmits light among the plurality of single-core optical fibers.

[0012] In the light diffusing device according to the present invention, the end face of the single-core optical fiber from which light is emitted is inclined with respect to the extending direction of the single-core optical fiber and with respect to a direction perpendicular to the extending direction.

[0013] In addition, in the light diffusing device according to the present invention, the light refraction section is detachable from the optical transmission cable, and the light refraction section having a different irradiation range at the point where light is irradiated can be attached to the optical transmission cable.

[0014] In the light diffusing device according to the present invention, the distance of the light refraction section from the tip of the optical transmission cable can be changed in a state where the light refraction section is attached to the tip of the optical transmission cable.

[0015] The light diffusing device according to the present invention further includes a cylindrical connecting member that connects the optical transmission cable and the light refraction portion.

[0016] In the light diffusing device according to the present invention, the light transmitted by the optical transmission cable has a wavelength of 670 nm or more and 700 nm or less.

[0017] A medical device according to the present invention is equipped with the light diffusing device. [Effects of the Invention]

[0018] According to the present invention, when the distal end of the optical transmission cable is inserted into the human body or positioned near the surface of a tumor, it is possible to irradiate laser light in multiple directions, thereby making it possible to change the location to be irradiated with laser light without inserting or removing the optical transmission cable from the human body, thereby shortening the time required for photoimmunotherapy.In addition, it is possible to irradiate laser light to locations that cannot be irradiated with laser light using conventional light diffusing devices, thereby expanding the irradiation range within the human body.Furthermore, it is possible to improve the operability of the light diffusing device. [Brief explanation of the drawings]

[0019] [Figure 1] FIG. 1 is a schematic diagram of a light diffusing device according to a first embodiment of the present invention. [Figure 2] FIG. 2 is a cross-sectional view of a main part of the light diffusing device according to the first embodiment of the present invention. [Figure 3] FIG. 3 is a schematic diagram illustrating the path of laser light in the light diffusing device according to the first embodiment of the present invention. [Figure 4] FIG. 4 is a schematic diagram illustrating a method for switching the irradiation direction in the light diffusing device according to the first embodiment of the present invention. [Figure 5] FIG. 5 is a cross-sectional view of a main part showing another example of the optical transmission cable of the light diffusing device according to the first embodiment of the present invention. [Figure 6] FIG. 6 is a cross-sectional view of a main part showing another example of the optical transmission cable of the light diffusing device according to the first embodiment of the present invention. [Figure 7] FIG. 7 is a cross-sectional view of a main part of a light diffusing device according to the second embodiment of the present invention. [Figure 8] FIG. 8 is a cross-sectional view of a main part of a light diffusing device according to a third embodiment of the present invention. [Figure 9] FIG. 9 is a cross-sectional view of a main part of a light diffusing device according to a fourth embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0020] First Embodiment Figures 1 to 6 show a first embodiment of the present invention. Figure 1 is a schematic diagram of a light diffusing device, Figure 2 is a cross-sectional view of the light diffusing device, Figure 3 is a schematic diagram explaining the path of laser light in the light diffusing device, Figure 4 is a schematic diagram explaining a method of switching the irradiation direction in the light diffusing device, Figure 5 is a cross-sectional view of an optical transmission cable, and Figure 6 is a cross-sectional view showing another example of an optical transmission cable.

[0021] The light diffusing device 1 of this embodiment is mounted on a medical device that performs photoimmunotherapy, which is one of the cancer treatment methods. Photoimmunotherapy treats cancer by administering to the human body a drug consisting of an antibody A that binds to cancer cells C and a substance that reacts to light, and then irradiating the drug that has bound to the cancer cells C with laser light L to destroy the cancer cells C, as shown in Fig. 1. Note that the present invention is not limited to photoimmunotherapy, and can also be used in treatment methods that use laser light, such as photodynamic therapy.

[0022] As shown in Figures 2 and 4, the light diffusion device 1 includes a laser oscillator 10 as a light source for generating laser light L, an optical transmission cable 20 for transmitting the laser light L generated by the laser oscillator 10, an optical refraction section 30 for refracting the laser light L emitted from the optical transmission cable 20, a connecting member 40 for connecting the optical transmission cable 20 and the optical refraction section 30, and an irradiation direction switching section 50 for changing the irradiation direction of the laser light L irradiated through the optical refraction section 30 toward the optical transmission cable 20.

[0023] The laser oscillator 10 has a semiconductor laser, and generates laser oscillation by passing electricity through the semiconductor laser to generate laser light L. The laser oscillator 10 generates red laser light L having a wavelength of 670 nm or more and 700 nm or less.

[0024] 1, 2, and 4, the optical transmission cable 20 has a multi-core optical fiber in which a plurality of cores 22 serving as optical transmission paths are provided inside one cladding 21. The multi-core optical fiber has an outer diameter of, for example, 250 μm, and the outer diameter of each core 22 is, for example, 30 μm. The optical transmission cable 20 transmits laser light L generated in the laser oscillator 10 through a selected core 22 of the plurality of cores 22 by the irradiation direction switching unit 50, and emits the laser light L from the tip.

[0025] The light refraction unit 30 is disposed at the tip of the optical transmission cable 20 and refracts the laser beams L emitted from the multiple cores 22 at the end of the optical transmission cable 20 so that the irradiation directions of the laser beams L are different from each other. The light refraction unit 30 is a lens having an incident surface 31, onto which the light emitted from the tip of the optical transmission cable 20 is incident, formed as a curved surface that protrudes toward the optical transmission cable 20, and an exit surface 32, from which the incident light exits, also formed as a curved surface that protrudes in the light exit direction. The light refraction unit 30 is, for example, a spherical ball lens having a refractive index of 1.5 and a diameter of 1 mm. As shown in FIG. 3 , the light refraction unit 30 refracts the laser beams L emitted from the tip of the optical transmission cable 20 at the incident surface 31 to make them incident, and refracts the incident laser beams L at the exit surface 32 to make them exit. The light refracting section 30 refracts the laser light L emitted from the tip of the optical transmission cable 20 at an angle of up to 90 degrees with respect to the extending direction of the core 22 at the tip side of the optical transmission cable 20 .

[0026] The connecting member 40 is made of, for example, a soft resin material and is formed in a cylindrical shape. As shown in Figures 1 and 2, one end of the connecting member 40 is connected to the tip of the optical transmission cable 20, and the other end holds the light refraction section 30 by press-fitting the light refraction section 30.

[0027] As shown in Fig. 4, the irradiation direction switching unit 50 is an optical selection element that causes the laser light L emitted from the laser oscillator 10 to be incident on a set core 22 out of the multiple cores 22 of the optical transmission cable 20. The irradiation direction switching unit 50 sets the core 22 onto which the laser light L is to be incident, for example, by a changeover switch. The irradiation direction switching unit 50 may also be configured to cause the laser light L to be incident on two or more cores 22 simultaneously. Examples of optical selection elements include a Mach-Zehnder interferometer optical switch and a MEMS optical switch.

[0028] When the light diffusion device 1 configured as described above is used in photoimmunotherapy, the tip of the optical transmission cable 20 including the light refraction section 30 and the connecting member 40 is inserted into the human body or positioned near the surface of the tumor, and laser light L is irradiated onto the drug that has reached the cancer cells C.

[0029] Here, when inserting the tip end of the optical transmission cable 20 into the human body or positioning it near the surface of a tumor, general medical equipment such as a puncture needle, cannula, tube, catheter, or endoscope can be used in combination.

[0030] At this time, the laser light L generated in the laser oscillator 10 propagates through a core 22 selected from the multiple cores 22 of the optical transmission cable 20 by the irradiation direction switching unit 50, and is emitted from the tip of the optical transmission cable 20. The laser light L emitted from the tip of the optical transmission cable 20 is refracted at the curved incident surface 31 of the light refracting unit 30, and is refracted at the curved exit surface 32, and is irradiated onto a target location inside the human body.

[0031] Furthermore, when the tip of the optical transmission cable 20 is inserted into the human body or positioned near the surface of a tumor, in order to change the location within the human body to which the laser light L is irradiated, the irradiation direction switching unit 50 switches the core 22 that propagates the laser light L from among the multiple cores 22 of the optical transmission cable 20, and irradiates the laser light L to another location within the human body, as shown in Figures 4(a) and 4(b).

[0032] Thus, the light diffusion device 1 of this embodiment includes an optical transmission cable 20 having a plurality of cores 22 through which the laser light L emitted from the laser oscillator 10 is transmitted, and an optical refraction section 30 provided at the tip of the optical transmission cable 20 and refracting each of the laser lights L emitted from the plurality of cores 22 so that the irradiation directions are different from each other.

[0033] Furthermore, the medical device of this embodiment is equipped with the light diffusing device 1.

[0034] This allows the laser light L to be irradiated in multiple directions when the distal end of the optical transmission cable 20 is inserted into the human body or positioned near the surface of a tumor, making it possible to change the location to be irradiated with the laser light L without inserting or removing the optical transmission cable 20 from the human body, thereby shortening the time required for photoimmunotherapy. Also, since it is now possible to irradiate the laser light L to locations that could not be irradiated with the laser light L using conventional light diffusing devices, it is possible to expand the irradiation range within the human body. Furthermore, it is possible to improve the operability of the light diffusing device 1.

[0035] Furthermore, it is preferable that the light refraction section 30 is a lens in which an incident surface 31 into which the laser light L emitted from the multiple cores 22 is incident is formed as a curved surface that protrudes toward the optical transmission cable 20, and an exit surface 32 from which the incident laser light L exits is formed as a curved surface that protrudes in the emission direction of the laser light L.

[0036] As a result, the laser light L emitted from the tip of the optical transmission cable 20 is refracted at the incident surface 31 and the exit surface 32, making it possible to increase the irradiation angle of the laser light L relative to the extension direction of the core 22 at the tip side of the optical transmission cable 20, and making it possible to irradiate the laser light L over a wide area within the human body when the optical transmission cable 20 is inserted into the human body or positioned near the surface of a tumor.

[0037] Furthermore, it is preferable that the optical transmission cable 20 has a multi-core optical fiber in which multiple cores 22 are provided in one clad 21, and the irradiation direction of the laser light L is switched by switching the core 22 that transmits the laser light L among the multiple cores 22.

[0038] This makes it possible to switch the irradiation direction of the laser light L by switching the core 22 that transmits the laser light L, so that the irradiation direction of the laser light L can be switched by a simple operation.

[0039] It is also preferable to provide a cylindrical connecting member 40 that connects the optical transmission cable 20 and the light refraction section 30 together.

[0040] This makes it possible to connect the light refraction section 30 to the optical transmission cable 20 with a simple structure, thereby enabling a reduction in manufacturing costs.

[0041] Furthermore, it is preferable that the laser light L transmitted by the optical transmission cable 20 has a wavelength of 670 nm or more and 700 nm or less.

[0042] This makes it possible to reliably react with drugs containing antibody A in photoimmunotherapy.

[0043] In the above embodiment, the optical transmission cable 20 includes a multi-core optical fiber having a plurality of cores 22 provided in one cladding 21. However, the present invention is not limited to this. As shown in FIG. 5, the optical transmission cable 20 may include a plurality of single-core optical fibers 23, each having a single core provided in one cladding, and may be formed by bundling the plurality of single-core optical fibers 23. In this case, the irradiation direction of the laser light can be switched by a simple configuration in which the laser oscillator 10 is connected to the plurality of single-core optical fibers 23 via connectors, without using the irradiation direction switching unit 50. Furthermore, as shown in FIG. 6, the optical transmission cable 20 may be formed by bundling a plurality of types of single-core optical fibers 23, 24 having different outer diameters. Furthermore, as shown in FIG. 3, the end face 23a of the single-core optical fiber 23 from which the laser light L is emitted may be inclined with respect to the extending direction of the single-core optical fiber 23 and a direction perpendicular to the extending direction.

[0044] In this way, it is preferable that the optical transmission cable 20 has a plurality of single-core optical fibers 23, 24, each having one core provided in one cladding, and that the irradiation direction of the laser light L is switched by switching the single-core optical fiber 23, 24 that transmits the laser light L among the plurality of single-core optical fibers 23, 24.

[0045] As a result, the irradiation direction of the laser light L can be switched by switching the single-core optical fibers 23, 24 that transmit the laser light L, so that the irradiation direction of the laser light L can be switched by a simple operation.

[0046] Moreover, it is preferable that the end face 23a of the single-core optical fiber 23 from which light is emitted is inclined with respect to the extending direction of the single-core optical fiber 23 and with respect to a direction perpendicular to the extending direction.

[0047] This makes it possible to increase the angle of incidence of the laser light L with respect to the incident surface 31 of the light refracting section 30, and therefore the refraction angle of the laser light L at the light refracting section 30.

[0048] Second Embodiment 7 is a cross-sectional view of a main part of a light diffusing device according to a second embodiment of the present invention, in which the same components as those in the previous embodiment are denoted by the same reference numerals.

[0049] In the light diffusing device 1 of this embodiment, the light refraction section 30 is configured to be detachable from the light transmission cable 20. Specifically, the connecting member 40 holding the light refraction section 30 is configured to be detachable from the light transmission cable 20. This allows the light diffusing device 1 to attach light refraction sections 30 having different irradiation ranges of the laser light L to the light transmission cable 20, as shown in FIGS. 7(a) and 7(b).

[0050] 7(a), the light diffusing device 1 is capable of changing a distance D from the tip of the optical transmission cable 20 to the light refraction portion 30. This allows the light diffusing device 1 to change the irradiation range and focal length of the laser light L by adjusting the distance D. The distance D can be adjusted, for example, within a range of 0 mm to 3 mm.

[0051] As described above, according to the light diffusing device 1 of this embodiment, as in the first embodiment, it is possible to irradiate the laser light L in multiple directions when the distal end of the optical transmission cable 20 is inserted into the human body or positioned near the surface of the tumor. This makes it possible to change the location to be irradiated with the laser light L without inserting or removing the optical transmission cable 20 from the human body, thereby shortening the time required for photoimmunotherapy. Furthermore, it is possible to irradiate the laser light L to locations that cannot be irradiated with the laser light L using conventional light diffusing devices, thereby expanding the irradiation range within the human body. Furthermore, it is possible to improve the operability of the light diffusing device 1.

[0052] Furthermore, it is preferable that the light refraction section 30 is detachable from the optical transmission cable 20, and that the optical transmission cable 20 can be fitted with light refraction sections 30 with different irradiation ranges at the location inside the human body where light is irradiated.

[0053] This makes it possible to use the optimal light refracting unit 30 depending on the condition inside the human body that is the target of irradiation with the laser light L, thereby enabling efficient photoimmunotherapy. Furthermore, it becomes possible to suppress irradiation of laser light to healthy cells, thereby reducing the invasiveness to the body of the patient undergoing photoimmunotherapy.

[0054] Moreover, it is preferable that the distance D of the light refraction section 30 from the tip of the optical transmission cable 20 be changeable in a state where the light refraction section 30 is attached to the tip of the optical transmission cable 20 .

[0055] This makes it possible to change the irradiation range and focal length of the laser light L without attaching or detaching the light refraction section 30 to the optical transmission cable 20, thereby enabling efficient photoimmunotherapy.

[0056] <Third embodiment> FIG. 8 shows a third embodiment of the present invention and is a cross-sectional view of a main part of a light diffusing device.

[0057] In the light diffusion device 1 of this embodiment, the light refraction section 30 is positioned at a distance from the tip of the optical transmission cable 20, and an auxiliary light refraction section 33 is attached to the end face of each core 22 at the tip of the optical transmission cable 20 for refracting the laser light L emitted from each core before it enters the incident surface 31 of the light refraction section 30.

[0058] The auxiliary light refracting unit 33 is, for example, a prism formed in the shape of a triangular prism, and refracts the laser light L emitted from each core 22. The laser light L refracted in the auxiliary light refracting unit 33 is refracted two more times in the light refracting unit 30, and is irradiated onto a target location inside the human body.

[0059] As described above, the light diffusing device 1 of this embodiment, like the first embodiment, can irradiate laser light L in multiple directions when the distal end of the optical transmission cable 20 is inserted into the human body or positioned near the surface of a tumor. This allows the location to be irradiated with laser light L to be changed without inserting or removing the optical transmission cable 20 from the human body, thereby shortening the time required for photoimmunotherapy. Furthermore, it is possible to irradiate laser light L to locations that cannot be irradiated with laser light L using conventional light diffusing devices, thereby expanding the irradiation range within the human body. Furthermore, the operability of the light diffusing device 1 can be improved.

[0060] In addition, an auxiliary light refracting section 33 that refracts the laser light L is provided between the tip of the optical transmission cable 20 and the light refracting section 30 .

[0061] This makes it possible to increase the angle of incidence of the laser light L with respect to the incident surface 31 of the light refracting section 30, and therefore the refraction angle of the laser light L at the light refracting section 30.

[0062] <Fourth embodiment> FIG. 9 is a cross-sectional view of a main part of a light diffusing device according to a fourth embodiment of the present invention.

[0063] In the light diffusion device 1 of this embodiment, the light refraction section 30 is positioned at a distance from the tip of the optical transmission cable 20, and a collimator lens 34 is attached between the end face of each core 22 at the tip of the optical transmission cable 20 and the light refraction section 30, so that the laser light L emitted from each core 22 and before entering the incident surface 31 of the light refraction section 30 is incident on the incident surface 31 of the light refraction section 30 while maintaining its outer diameter without diffusing or converging.

[0064] The laser light L emitted from the end face of each core 22 at the tip of the optical transmission cable 20 is refracted by the collimator lens 34 to become collimated light, and enters the incident surface 31 of the light refracting section 30 .

[0065] As described above, the light diffusing device 1 of this embodiment, like the first embodiment, can irradiate laser light L in multiple directions when the distal end of the optical transmission cable 20 is inserted into the human body or positioned near the surface of a tumor. This allows the location to be irradiated with laser light L to be changed without inserting or removing the optical transmission cable 20 from the human body, thereby shortening the time required for photoimmunotherapy. Furthermore, it is possible to irradiate laser light L to locations that cannot be irradiated with laser light L using conventional light diffusing devices, thereby expanding the irradiation range within the human body. Furthermore, the operability of the light diffusing device 1 can be improved.

[0066] In the above embodiment, a ball lens is used as the light refracting unit 30 that refracts the laser beams L emitted from the cores 22 so that the directions of the laser beams L are different from each other, but the present invention is not limited to this. If it is possible to refract the laser beams L emitted from the cores 22 so that the directions of the laser beams L are different from each other, it is not necessary to use a lens, and for example, a polygonal prism can be used as the light refracting unit.

[0067] In the above embodiment, a spherical ball lens is shown as a lens in which the incident surface 31 onto which the laser light L emitted from the multiple cores 22 is incident is formed as a curved surface that protrudes toward the optical transmission cable 20, and the exit surface 32 from which the incident laser light L exits is formed as a curved surface that protrudes in the emission direction of the laser light L, but this is not limited to this. As long as the incident surface onto which the laser light L emitted from the multiple cores 22 is incident is formed as a curved surface that protrudes toward the optical transmission cable 20, and the exit surface from which the incident laser light L exits is formed as a curved surface that protrudes in the emission direction of the laser light L, the lens may have, for example, an elliptical or cylindrical cross-sectional shape. Furthermore, multiple cylindrical lenses may be used. [Explanation of symbols]

[0068] 1. Light diffusion device 10 Laser oscillator 20 Optical transmission cable 21 Clad 22 cores 23 Single-core optical fiber 23a End face 30 Light refraction section 31 Incidence plane 32 Exit surface 33 Auxiliary light refraction unit 40 Connecting member 50 Irradiation direction switching unit

Claims

1. an optical transmission cable having a plurality of optical transmission paths through which light emitted from a light source is transmitted; a light refracting section provided at a tip end of the optical transmission cable and refracting each of the lights emitted from the plurality of optical transmission paths so that the irradiation directions are different from each other; The distance of the light refraction section from the tip of the optical transmission cable can be changed in a state where the light refraction section is attached to the tip of the optical transmission cable. Light diffuser.

2. The light refraction section is a lens having an incident surface onto which light emitted from the plurality of optical transmission paths is incident, the incident surface being formed as a curved surface that protrudes toward the optical transmission cable, and an exit surface from which the incident light exits being formed as a curved surface that protrudes in the direction of light emission. The light diffusing device of claim 1 .

3. the optical transmission cable includes a multi-core optical fiber in which a plurality of cores serving as the optical transmission paths are provided in one clad, The direction of light irradiation is switched by switching the core that transmits light among the plurality of cores. The light diffusing device according to claim 1 or 2.

4. An auxiliary light refraction section is provided between the tip of the optical transmission cable and the light refraction section to refract light. The light diffusing device of claim 3 .

5. the optical transmission cable includes a plurality of single-core optical fibers each having a core as the optical transmission path provided in a clad; The direction of light irradiation is switched by switching the single-core optical fiber that transmits light among the plurality of single-core optical fibers. The light diffusing device according to claim 1 or 2.

6. The single-core optical fiber has an end face from which light is emitted that is inclined with respect to the extending direction of the single-core optical fiber and with respect to a direction perpendicular to the extending direction. The light diffusing device of claim 5 .

7. the optical refraction unit is detachable from the optical transmission cable, The optical transmission cable can be fitted with the light refraction section, which has a different irradiation range at the point where light is irradiated. The light diffusing device according to claim 1 .

8. a cylindrical connecting member that connects the optical transmission cable and the light refraction portion; The light diffusing device according to any one of claims 1 to 7.

9. The light transmitted by the optical transmission cable has a wavelength of 670 nm or more and 700 nm or less. The light diffusing device according to any one of claims 1 to 8.

10. A device equipped with the light diffusion device according to claim 9. Medical equipment.

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