Compositions containing sodium hyaluronate and their use

Abstract

A composition containing sodium hyaluronate and its use. The water activity of the composition is 0.330-0.930, and the mass percentage of the sodium hyaluronate in the composition is 0.01-5%. The composition includes sodium hyaluronate and a water activity regulator. By controlling the water activity, the composition can reduce the risk of corrosion of cast iron equipment, ensure the uniformity of the coating of paper products, improve the flexibility of paper products, and give paper products certain emollient properties.

Description

Technical Field

[0001] The present invention relates to the technical field of paper product manufacturing, and particularly relates to a composition containing sodium hyaluronate and its use.

Background Art

[0002] In recent years, compared with ordinary paper towels, super soft paper that is less likely to damage the skin barrier when wiping the skin has gained popularity in the market.

[0003] Usually, super soft paper is obtained by applying a certain type of finishing liquid to ordinary paper towels.

[0004] In order to further improve the softness of super soft paper to the skin, in this study, an attempt was made to add sodium hyaluronate polymer to the formulation of the finishing liquid. However, since sodium hyaluronate polymer is a strong electrolyte, when a water-based finishing liquid is added, electrochemical corrosion occurs in the manufacturing equipment containing cast iron, and the corroded yellow-brown rust water contaminates the paper towel products.

Summary of the Invention

[0005] In view of the above problems, the present invention provides a composition containing sodium hyaluronate, which is used for finishing paper products. By controlling the water activity of the composition, the risk of corrosion of cast iron equipment can be reduced, and the uniformity of the coating of paper products can be ensured.

[0006] The specific technical solutions of the present invention are as follows.

[0007] 1. A composition containing sodium hyaluronate, wherein the water activity of the composition is 0.330 - 0.930, and the sodium hyaluronate is 0.01 - 5% by mass percentage in the composition. 2. The composition according to item 1, wherein the composition further contains a water activity regulator. 3. The composition according to item 1 or 2, wherein the molecular weight of the sodium hyaluronate is 1000 to 300 wDa, preferably 20 to 40 wDa. 4. The composition according to item 1 or 2, wherein the water activity regulator is a substance capable of forming hydrogen bonds with water, preferably a substance containing a hydroxyl group, a carbonyl group, or an aldehyde group, and more preferably glycerol, glucose, sucrose, sodium hyaluronate monomer, fructose, xylitol, mannose, arabinose, or sodium polyacrylate. 5. The composition according to any one of claims 1 to 4, wherein the water activity regulator is present in the composition in an amount of 10 to 95%, preferably 45 to 90%, by mass percentage. 6. Use of any one of the compositions described in paragraphs 1 to 5 in paper finishing. 7. A paper finishing liquid comprising the composition described in any one of items 1 to 5. 8. The paper finishing liquid described in item 7, further containing additives. 9. Paper products containing the paper finishing liquid described in item 7 or 8. 10. The paper product according to item 9, wherein the amount of the paper finishing liquid applied is 1 to 50% by weight. [Effects of the Invention]

[0008] The compositions provided by the present invention can reduce the risk of corrosion of cast iron equipment and ensure uniformity of coatings on paper products by controlling the water activity of the compositions.

[0009] The composition of the present invention, by controlling two elements, sodium hyaluronate content and water activity value, can be used as a coating for paper products to reduce the corrosion rate of cast iron equipment, ensure uniformity of the coating on paper products, improve the flexibility of paper products, and give paper products certain emollient properties. [Modes for carrying out the invention]

[0010] The present invention will now be described in detail. While specific embodiments of the present invention have been shown, it should be understood that the present invention can be embodied in various forms and should not be limited to the embodiments described herein. Rather, these embodiments are provided to enable a more complete understanding of the present invention and to fully convey the scope of the invention to those skilled in the art.

[0011] Note that specific terminology is used in the specification and claims to refer to specific components. Those skilled in the art will understand that different nouns may be used to refer to the same component. This specification and claims do not use differences in nouns as a way to distinguish components, but rather use differences in the function of the components as the criterion for distinction. The words “contain” or “include” as used throughout the specification and claims are open terms and should be interpreted as “include, but not limited to.” The following description is a preferred embodiment for carrying out the invention, but it is intended to be a general principle of the specification and does not limit the scope of the invention. The scope of protection of the invention shall be determined by the appended claims.

[0012] The present invention provides a composition containing sodium hyaluronate, wherein the water activity is 0.330 to 0.930, and the amount of sodium hyaluronate in the composition is 0.01 to 5% by mass percentage.

[0013] For example, the water activity of the composition may be 0.330, 0.400, 0.500, 0.600, 0.700, 0.800, 0.900, 0.930, etc.

[0014] The sodium hyaluronate is present in the composition at a mass percentage of 0.01%, 0.05%, 0.1%, 0.5%, 1%, 2%, 3%, 4%, 5%, etc.

[0015] The water activity of the aforementioned composition refers to the water activity measured after adding water, where the water content in the total amount of the composition and water after adding water is 5-60% by mass.

[0016] In one embodiment, the water activity regulator is further included.

[0017] In one embodiment, the water activity regulator is present in the composition at a mass percentage of 10 to 95%, preferably 45 to 90%.

[0018] For example, the water activity regulator may be present in the composition at a mass percentage of 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 95%, etc.

[0019] In one embodiment, the molecular weight of the sodium hyaluronate is 1000 to 300 wDa, preferably 20 to 40 wDa, and more preferably 35 wDa.

[0020] For example, the molecular weight of the sodium hyaluronate may be 1000 Da, 5000 Da, 10 w Da, 20 w Da, 25 w Da, 30 w Da, 35 w Da, 40 w Da, 50 w Da, 100 w Da, 200 w Da, 300 w Da, etc.

[0021] In one embodiment, the water activity regulator is a substance capable of forming hydrogen bonds with water, and may be, for example, a low molecular weight substance, macromolecular weight substance, or high molecular weight substance having a hydroxyl group, carboxyl group, amino group, or aldehyde group, preferably glycerol, glucose, sucrose, sodium hyaluronate monomer, fructose, xylitol, mannose, arabinose, or sodium polyacrylate.

[0022] In one embodiment, the molecular weight of the sodium hyaluronate monomer is 380 Da.

[0023] In one embodiment, the water activity of the composition is 0.330 to 0.930, the sodium hyaluronate is 0.01 to 5% by mass in the composition, and the composition further contains a water activity regulator.

[0024] In one embodiment, the water activity of the composition is 0.330 to 0.930, the sodium hyaluronate is 0.01 to 5% by mass in the composition, the composition further contains a water activity regulator, the molecular weight of the sodium hyaluronate is 1,000 to 3,000,000 Da, preferably 200,000 to 400,000 Da.

[0025] In one embodiment, the water activity of the composition is 0.330 to 0.930, the sodium hyaluronate is 0.01 to 5% by mass in the composition, the composition further contains a water activity regulator, the molecular weight of the sodium hyaluronate is 1,000 to 3,000,000 Da, preferably 200,000 to 400,000 Da, the water activity regulator is a substance capable of forming a hydrogen bond with water, preferably a substance containing a hydroxyl group, a carbonyl group, or an aldehyde group, more preferably glycerol, glucose, sucrose, sodium hyaluronate monomer, fructose, xylitol, mannose, arabinose, or sodium polyacrylate.

[0026] In one embodiment, the water activity of the composition is 0.330 to 0.930, the sodium hyaluronate is 0.01 to 5% by mass in the composition, the composition further contains a water activity regulator, the molecular weight of the sodium hyaluronate is 1,000 to 3,000,000 Da, preferably 200,000 to 400,000 Da. The water activity regulator is a substance capable of forming a hydrogen bond with water, preferably a substance containing a hydroxyl group, a carbonyl group, or an aldehyde group, more preferably glycerol, glucose, sucrose, sodium hyaluronate monomer, fructose, xylitol, mannose, arabinose, or sodium polyacrylate, and the water activity regulator is 10 to 95% by mass in the composition, preferably 45 to 90%.

[0027] According to the above-described composition, the present invention allows for the control of the water activity of the composition using a water activity regulator, and for the use of sodium hyaluronate, it is possible to reduce the risk of corrosion of cast iron equipment and ensure the uniformity of the coating on paper products.

[0028] The present invention provides for the use of the above composition in the finishing of paper products.

[0029] The use of the above-described composition ensures uniformity of the coating on paper products during the manufacturing process and reduces the risk of corrosion of the cast iron equipment used.

[0030] The present invention provides a paper finishing liquid containing the above composition.

[0031] In one embodiment, the paper finishing liquid further comprises an additive.

[0032] The aforementioned additives are well known in the art and may include, for example, viscosity modifiers, preservatives, polymers (cationic polymers, nonionic polymers), salts, lipids, surfactants or emulsions, fragrances, silicone oils, mineral oils, vegetable oils, and the like.

[0033] Experiments have shown that when the above-mentioned paper finishing liquid is used in online spraying, if the water activity of the paper finishing liquid is less than 0.330, the uniformity of the paper finishing liquid on the paper (distribution of the amount applied) is affected, meaning that the diffusivity of the solution after spraying decreases.

[0034] Furthermore, the corrosiveness of the above-mentioned paper finishing solution on cast iron equipment was investigated by immersion experiments with iron pieces, and the degree of corrosiveness was evaluated based on the discoloration time of the immersion solution. In a manufacturing cycle (i.e., one cycle of the production line is 8 hours), if the discoloration time is 8 hours or more, the corrosiveness is considered to be within an acceptable range. The study found that when the water activity of the finishing solution is less than 0.930, the discoloration time is 8 hours or more.

[0035] The present invention, by using the above-mentioned paper finishing liquid and controlling its water activity within the range of 0.330 to 0.930, not only can a uniform coating of paper products be achieved, but the risk of corrosion of cast iron equipment can also be reduced.

[0036] The present invention provides a method for producing a paper finishing solution, comprising the step of dissolving sodium hyaluronate and a water activity regulator in water, preferably deionized water, to obtain a paper finishing solution.

[0037] The present invention provides a paper product containing the above-mentioned paper finishing liquid.

[0038] In one embodiment, the amount of paper finishing liquid applied is 1 to 50% by weight.

[0039] Because the composition of the present invention uses sodium hyaluronate and a water activity regulator, the water activity of the composition can be controlled within the range of 0.330 to 0.930, and when the resulting paper finishing liquid is applied to paper, the paper product can be uniformly coated. Furthermore, since the time until the iron piece rusts (rusting time) is 8 hours or more, the risk of corrosion of cast iron equipment used in the manufacture of paper products can be reduced, and the resulting paper product has high flexibility and certain emollient properties. [Examples]

[0040] This invention generally and / or specifically describes the materials and test methods used in the tests. In the following examples, unless otherwise specified, % means weight %. Unless the manufacturer of the reagents and equipment used is not indicated, they are all commercially available conventional reagent products.

[0041] Example 1 A paper finishing solution was obtained by dissolving sodium hyaluronate and a water activity regulator with different masses in deionized water. The amounts of sodium hyaluronate, water activity regulator, and deionized water in the paper finishing solution are shown in Table 1, with numbers 1 to 12.

[0042] Comparative Example 1 A paper finishing solution was obtained by dissolving sodium hyaluronate and a water activity regulator with different masses in deionized water. The amounts of sodium hyaluronate, water activity regulator, and deionized water in the paper finishing solution are shown in Table 1, with numbers 13 to 27.

[0043] [Table 1]

[0044] Test Example 1: Measurement of Sodium Hyaluronate Content The sodium hyaluronate content in the paper finishing agent was measured using the method described in patent CN109298112A, and the results are shown in Table 2.

[0045] [Table 2]

[0046] Experimental Example 2: Measurement of Water Activity A Swiss ROTRONIC Hygrolab-C1-SET tabletop water activator or equivalent equipment was used.

[0047] Ten ml each of the different paper finishing solutions obtained in Example 1 and Comparative Example 1 were placed in a sample cell for water activity detection. The sample cell was sealed with a test probe and left to stand for 1 hour in an environment of 25°C + / - 2°C. After the water activity reached a stable value, the water activity was recorded. Each sample was measured three times, and the average value was calculated. The results are shown in Table 3.

[0048] [Table 3]

[0049] Experimental Example 3: Corrosion of Cast Iron Equipment A clean PP bottle with a lid and a volume of 100 ml was used as the container. A piece of cast iron measuring 2cm x 4cm x 0.5cm was used. Before testing the iron pieces, surface rust was removed using sandpaper, and surface oil and contaminants were thoroughly cleaned using a surfactant. After cleaning, the surfactant was rinsed off with deionized water, and the pieces were dried with paper towels. Next, the iron pieces were placed in a container within one minute, and 90 ml each of the paper finishing solutions from Example 1 and Comparative Example 1 were used to completely immerse the iron pieces, and the container was sealed with a lid. The immersion mixture (iron pieces + paper finishing solution) was placed in a constant temperature oven at 25°C ± 2°C, and the color of the solution was observed every 30 minutes. The time it took for the immersion solution to change from colorless to a yellow (rust color) visible to the naked eye was recorded, and the results are shown in Table 4.

[0050] [Table 4]

[0051] Experimental Example 4: Uniformity of coating on paper products After spraying the paper finishing liquid described in Example 1 and Comparative Example 1, the paper product substrate was rolled into a roll, wrapped in PE film, and left to mature for 3 days. After maturation was complete, the outermost 10 layers of the roll paper were peeled off and samples were taken.

[0052] Thirty 5cm x 5cm paper samples were cut evenly along the CD direction of the roll paper (the direction perpendicular to the direction of movement when the paper is coated), and their weights were measured using a chemical balance within 30 minutes at 25°C + / -2°C. The results were recorded as M1, M2, M3, M4, ... M30.

[0053] These 30 samples were placed in a 105°C oven for 30 minutes, then immediately removed and weighed on a chemical balance at an environment of 25°C ± 2°C, and recorded as N1, N2, N3, ... N30.

[0054] The mass losses D1, D2, D3...D30 for each sample were calculated. Di=Mi-Ni The average mass loss is given by DN = (D1 + D2 + ... + D30) / 30; Calculate the standard deviation STD for D1 to D30. Next, the relative standard deviation (RSD) was calculated as STD / DN.

[0055] When the RSD is 5% or less, the coating on the paper product is considered uniform, and the measurement results are shown in Table 5.

[0056] [Table 5]

[0057] As described above, the composition of the present invention contains sodium hyaluronate and a water activity regulator, so after being prepared as a paper finishing solution, it can ensure uniformity of the coating on paper products and reduce the risk of corrosion of cast iron equipment. Furthermore, it can not only improve the flexibility of paper products but also impart certain emollient properties to them.

[0058] The above are merely preferred embodiments of the present invention and are not intended to limit the invention to other forms. Those skilled in the art can use the technical content disclosed above to make equivalent modifications or changes to equivalent embodiments. However, any simple changes, equivalent changes, and modifications made to the above embodiments based on the technical essence of the invention without departing from the technical concept of the present invention still fall within the scope of the technical concept of the present invention.

Claims

1. A composition comprising sodium hyaluronate and a water activity regulator, wherein the water activity of the composition is 0.330 to 0.930, the sodium hyaluronate is 0.01 to 5% by mass percentage in the composition, and the water activity regulator is glycerol, glucose, sucrose, or sodium hyaluronate monomer, and the water activity regulator is 45 to 95% by mass percentage in the composition.

2. The composition according to claim 1, wherein the molecular weight of the sodium hyaluronate is 1,000 to 3,000,000 Da.

3. The composition according to claim 1, wherein the molecular weight of the sodium hyaluronate is 200,000 to 400,000 Da.

4. The composition according to any one of claims 1 to 3, wherein the water activity regulator constitutes 45 to 90% by mass in the composition.

5. Use of the composition according to any one of claims 1 to 4 in paper finishing.

6. A paper finishing liquid comprising the composition according to any one of claims 1 to 4.

7. A paper product containing the paper finishing liquid described in claim 6.

8. A paper product to which the paper finishing liquid described in Claim 6 has been applied.

9. The paper product according to claim 8, wherein the amount of the paper finishing liquid applied is 1 to 50% by weight.

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