Model of mucus-covered mucosal tissue

Abstract

Provided are: a simulated mucus coated mucosal tissue model and an organ model; a medical procedure training method using the models; a method for producing the models; a kit and a device which include the models; and a lubricating composition for a mucosal tissue model.　The simulated mucus coated mucosal tissue model for medical procedure training simulates at least a portion of mucosal tissue of a living body, in which a surface simulating a mucosal surface of mucosal tissue is coated with a lubricating composition having a volume resistivity of 1.0E+00 to 1.0E+05 (1.0 to 1.0×105) Ω･cm and a viscosity at 25°C, as measured by a measurement method stipulated in JIS Z8803, of 1.0E+00 to 1.0E+05 (1.0 to 1.0×105) mPa･s.

Claims

1. The surface of a mucosal tissue model that mimics at least a portion of the mucosal tissue of living organisms, which mimics the mucosal surface of the mucosal tissue, has a volume resistivity of 1.0 to 1.0 × 10⁻⁶. ５ The viscosity is Ω·cm, and the viscosity at 25°C measured by the measurement method specified in JIS Z8803 is 1.0 to 1.0 × 10⁻⁶. ５ A simulated mucous membrane model for medical procedure training, coated with a lubricating composition at mPa·s, wherein the lubricating composition is designed to reproduce the continuous generation of bubbles in mucus during treatment of biological mucous membrane tissue using an energy device.

2. A model of simulated mucous membrane tissue according to claim 1, comprising a simulated blood vessel connected to a device capable of supplying simulated blood.

3. The simulated mucous membrane model according to claim 1 or 2, wherein the medical procedure is a procedure including incision or hemostasis of mucous membrane tissue using an energy device.

4. A simulated mucus-covered organ model for medical procedure training, comprising the simulated mucus-covered mucosal tissue model described in claim 1.

5. A model of a simulated mucus-covered organ according to claim 4, comprising a simulated blood vessel connected to a device capable of supplying simulated blood.

6. The simulated mucus-covered organ model according to claim 4 or 5, wherein the medical procedure is a procedure including incision or hemostasis of mucosal tissue using an energy device.

7. A method for training medical procedures using a simulated mucous membrane tissue model according to claim 1.

8. A method for training medical procedures using a simulated mucus-covered organ model as described in claim 4.

9. A method for training medical procedures according to claim 7 or 8, wherein the medical procedure is a procedure involving the incision or hemostasis of mucosal tissue using an energy device.

10. The surface of a mucosal tissue model that mimics at least a portion of the mucosal tissue of living organisms, with a volume resistivity of 1.0 to 1.0 × 10⁻⁶ ５ The viscosity is Ω·cm, and the viscosity at 25°C measured by the measurement method specified in JIS Z8803 is 1.0 to 1.0 × 10⁻⁶. ５ A method for producing a simulated mucous membrane tissue model for medical procedure training, comprising the step of coating with a lubricating composition having mPa·s, wherein the lubricating composition is a composition for reproducing continuous bubble generation in mucus during treatment of biological mucous membrane tissue using an energy device.

11. The manufacturing method according to claim 10, wherein the mucosal tissue model includes a simulated blood vessel connected to a device capable of supplying simulated blood.

12. The manufacturing method according to claim 10 or 11, wherein the medical procedure is a procedure including incision or hemostasis of mucosal tissue using an energy device.

13. The surface of an organ model, which includes a mucosal tissue model that mimics at least a portion of the mucosal tissue of a living organism, is a mucosal surface model of the mucosal tissue, with a volume resistivity of 1.0 to 1.0 × 10⁻⁶. ５ The viscosity is Ω·cm, and the viscosity at 25°C measured by the measurement method specified in JIS Z8803 is 1.0 to 1.0 × 10⁻⁶. ５ A method for manufacturing a simulated mucus-coated organ model for medical procedure training, comprising the step of coating with a lubricating composition having mPa·s, wherein the lubricating composition is a composition for reproducing continuous bubble generation in mucus during treatment of biological mucosal tissue using an energy device.

14. The manufacturing method according to claim 13, wherein the model of a simulated mucus-covered organ includes a simulated blood vessel connected to a device capable of supplying simulated blood.

15. The manufacturing method according to claim 13 or 14, wherein the medical procedure is a procedure including incision or hemostasis of mucosal tissue using an energy device.

16. Volume resistivity is 1.0 to 1.0 × 10 ５ The viscosity is Ω·cm, and the viscosity at 25°C measured by the measurement method specified in JIS Z8803 is 1.0 to 1.0 × 10⁻⁶. ５ A medical procedure training kit comprising a lubricating composition with mPa·s and a mucosal tissue model that mimics at least a portion of the mucosal tissue of a living organism, wherein the lubricating composition is a composition for reproducing the continuous generation of bubbles in mucus during treatment of mucosal tissue of a living organism using an energy device.

17. The medical procedure training kit according to claim 16, wherein the mucosal tissue model includes a simulated blood vessel connected to a device capable of supplying simulated blood.

18. A medical procedure training kit according to claim 16 or 17, wherein the medical procedure is a procedure involving the incision or hemostasis of mucosal tissue using an energy device.

19. The volume resistivity is 1.0 to 1.0×10 ５ Ω·cm, and the viscosity at 25°C measured by the measurement method defined in JIS Z8803 is 1.0 to 1.0×10 ５ mPa·s. The medical procedure training kit includes a lubricating composition and an organ model including a mucosal tissue model simulating at least a part of a living body's mucosal tissue, and the lubricating composition is a composition for reproducing continuous bubble generation in mucus during treatment of a living body's mucosal tissue using an energy device.

20. A medical procedure training kit according to claim 19, wherein the organ model includes a simulated blood vessel connected to a device capable of supplying simulated blood.

21. A medical procedure training kit according to claim 19 or 20, wherein the medical procedure is a procedure involving the incision or hemostasis of mucosal tissue using an energy device.

22. A medical procedure training device comprising a simulated mucus-covered organ model according to claim 4 or 5, and organ models that mimic one or more other types of organs.

23. Volume resistivity is 1.0 to 1.0 × 10 ５ The viscosity is Ω·cm, and the viscosity at 25°C measured by the measurement method specified in JIS Z8803 is 1.0 to 1.0 × 10⁻⁶. ５ A lubricating composition having mPa·s, A lubricating composition for coating mucosal tissue models, intended for use in coating a surface that mimics the mucosal surface of mucosal tissue in a mucosal tissue model, wherein the lubricating composition reproduces the continuous generation of bubbles in mucus during treatment of biological mucosal tissue using an energy device.

24. The lubricating composition for coating a mucosal tissue model according to claim 23, comprising a simulated blood vessel connected to a device that can supply the mucosal tissue model with simulated blood.

25. A lubricating composition for coating mucosal tissue models according to claim 23 or 24, used to reproduce in a mucosal tissue model the continuous generation of bubbles in mucus during treatment of biological mucosal tissue using an energy device.

26. The lubricating composition for coating a mucosal tissue model according to claim 25, wherein the treatment of the mucosal tissue of a living organism using an energy device is a treatment including incision or hemostasis of the mucosal tissue.

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