System and method for a stimulating syringe pump accommodating syringes of different sizes

Abstract

A stimulating syringe pump (100) for accommodating syringes (102) of different sizes is provided. This system is provided by an enclosure having a base (134) having a proximal end (132) and a distal end (134), and the base (134) is structured and arranged to accommodate a syringe (102) slidably disposed within a chamber (110) having an outlet for a plunger (122), the chamber (110) has a length (116) and a diameter (118), and the plunger (122) has a head (124); the base (134); the pusher (202) structured and arranged to contact the head (124) of the plunger (122); a puller (200) slidably coupled with the base (134); and a sizer (220) structured and arranged to determine the size of the chamber (110). It includes an adjustable actuator (208) structured and arranged to provide a constant force between the pusher (202) and the puller (200), wherein the constant force is adjustablely selected by the size of the chamber (110). A related method of use (1100) is also provided.

Description

Technology Field

[0001] Cross-reference of related applications

[0002] This application was filed on November 28, 2023, and claims the benefit of 35 USC § 119(e) of U.S. Provisional Application No. 63 / 526,176, titled “SYSTEM AND METHOD FOR A CONSTANT FORCE SYRINGE PUMP ACCOMMODATING SYRINGES OF DIFFERENT SIZES,” the disclosure of which is incorporated herein by reference.

[0003] Field of invention

[0004] The present invention generally relates to a mechanical syringe pump for delivering liquid medication to a patient, and more specifically, to a mechanical stimulating syringe pump that adapts advantageously to different sizes of syringes to ensure that appropriate stimulating force is applied to the patient for the administration of liquid medication according to the prescribed drug flow rate for syringes currently in use. Background Technology

[0005] Infusion systems for the delivery of liquid medicines are widely used and relied upon by both patients and caregivers to provide infusion therapy.

[0006] One form of infusion therapy is immunoglobulin (Ig) therapy, which is frequently used to improve the quality of life of patients with conditions such as primary immune deficiency (PID), secondary immune deficiency (SID), chronic inflammatory demyelinating polyradiculoneuropathy (CIPD), and severe combined immunodeficiency (SCID). Historically, Ig therapy was administered intravenously (IVIg) every 3 to 4 weeks, which can result in inconsistent serum levels and a burdensome infusion experience for the patient.

[0007] Subcutaneous Ig therapy (SCIg) is a more convenient option that enables consistent serum levels and can be performed at home. Subcutaneous administration has been shown to maintain more consistent IgG blood levels, providing patients with a consistent quality of life and fewer breakthrough infections. Furthermore, infusion into the subcutaneous tissue is often preferred over intravenous delivery, which is frequently accompanied by flu-like symptoms following such infusion. However, SCIg presents its own challenges, such as the need for the patient to prepare and administer the infusion themselves.

[0008] At least one challenge relates to pump systems used for subcutaneous Ig therapy. Essentially, there are two types of home pump systems: constant pressure and constant flow. In constant flow systems, pressure increases in response to any flow restriction, regardless of whether the restriction is a pressure buildup within the patient's tissues or elements of the delivery system. This can result in the administration of fluids at unsafe pressures. Consequently, patients may experience a wide range of symptoms, including but not limited to anaphylaxis, overdose, histamine reactions, morbidity, and mortality.

[0009] In contrast, constant pressure pumps generate safe and limited constant pressure. If there is a kink in the tubing causing blockage in the infusion system or a blockage in the patient's body (such as tissue saturation), such blockage results in resistance to flow and affects the flow rate rather than the pressure; that is, the flow rate decreases as the pressure increases. Consequently, constant pressure pump systems have been found to be safer and often more financially acceptable to users.

[0010] However, there is also the issue of dosage. Often, the dosage is predetermined and provided in a pre-filled syringe that can be placed inside a pressure pump. However, each person differs in size, shape, and tissue composition, among many other factors. Body weight alone may require a 17g (85ml) dose of Ig therapy for one person, while another may only need 10g. However, syringes also come in different sizes, such as 5, 10, 20, and 50ml, each varying in diameter as well as length.

[0011] If medication is administered into a syringe other than one designed with a constant pressure pump, the patient or caregiver must transfer the liquid medication from the pre-filled syringe to a new, sterile, pump-compatible syringe. Such a transfer process is not problem-free and introduces opportunities for problems including, but not limited to, complete transfer, contamination, and general stress and anxiety.

[0012] Because the 10ml syringe differs in length and diameter from the 50ml syringe, a different amount of force must be applied to the syringe to generate the necessary static pressure to provide the same expected and intended initial flow rate, and a safety device must also be provided to reduce the flow rate from the pump as resistance pressure increases due to problems within the infusion system itself or the patient.

[0013] To put it more simply, if a 10ml syringe is placed in a pump designed for a 50ml syringe, the force applied to the 10ml syringe will be much greater than appropriate. Likewise, if a 50ml syringe is placed in a pump intended for a 10ml syringe, the force applied will be too small and the intended flow rate will not be provided.

[0014] In fact, U.S. Patent 10,376,636, titled “Compact Mechanical Pump,” specifically teaches that each embodiment of the disclosed compact mechanical pump is intended for a syringe of a specific size, and that “if a user attempts to use a 30 mL syringe with a pump for a 20 mL syringe, a rejection stamp will eject the syringe from the base when attempting to close the cover.”

[0015] Therefore, there is a need for a method and system capable of overcoming one or more of the aforementioned identified challenges. The problem to be solved

[0016] The present invention solves the problems of the prior art by providing a novel system and method for a mechanical power pump assembly as a power syringe pump that accommodates syringes of different sizes. means of solving the problem

[0017] In particular, and merely as an example, according to one embodiment of the present invention, a stimulant syringe pump assembly for accommodating syringes of different sizes is provided, said stimulant syringe pump assembly comprises: a base having a proximal end and a distal end, said base being structured and arranged to accommodate a syringe having a plunger slidably disposed within a chamber having an outlet, said chamber having a length and a diameter, said plunger having a head; said base; a pusher slidably coupled to said base, said pusher being structured and arranged to contact the head of said plunger; and a puller slidably coupled to said base. A controllable actuator structured and arranged to provide a constant force between the pusher and the puller, wherein the controllable actuator is provided by at least one spring connected between the pusher and the puller and providing a first force and a controllable brake structured and arranged to provide a controllable braking force to reduce the first force, wherein the controllable actuator is regulated by adjusting the controllable braking force applied to reduce the first force; accordingly, when the syringe is seated on the base, moving the puller in a distal sliding manner causes the pusher to contact the head of the plunger and apply a constant force, wherein the constant force is sufficient to move the plunger of the syringe and dispense liquid from the chamber at a desired flow rate; and a cover connected to the base, wherein a linkage is coupled between the cover and the puller and is structured and arranged to convert the opening of the cover into the movement of the puller and the pusher toward the proximal end, and when the syringe is positioned, the closing of the cover causes the pusher to engage the plunger, moves the puller toward the distal end, and engages the adjustable actuator; the cover is included.

[0018] In another embodiment, a stimulant syringe pump assembly for accommodating syringes of different sizes is provided, said stimulant syringe pump assembly comprises: an expandable base having a proximal end and a distal end, said base comprising a first base section and a second base section, said first base section slidably coupled with the second base section so that the first base section and the second base section can slide relative to each other between a compression position and an expansion position, said base in the expansion position adapted to accommodate a syringe having a plunger slidably disposed within a chamber having an outlet, said chamber having a length and a diameter, said plunger having a head, said expandable base; a pusher slidably coupled with said base and dimensioned to contact the head of said plunger; and a puller slidably coupled with said base. A controllable actuator structured and arranged to provide a force between the pusher and the puller, wherein the controllable actuator is provided by at least one spring connected between the pusher and the puller to provide a first force and a controllable brake structured and arranged to provide a controllable braking force to reduce the first force, wherein the controllable actuator is regulated by adjusting the controllable braking force applied to reduce the first force; accordingly, when the syringe is seated on the base, sliding the puller in a distal direction causes the pusher to contact the head of the plunger and apply a substantial force, and the force is sufficient to move the plunger of the syringe and dispense liquid from the chamber at a desired flow rate; and an expandable cover pivotally connected to the proximal end of the base, wherein a linkage is pivotally connected between the cover and the puller and is structured and arranged to convert the opening of the cover into movement of the puller and the pusher toward the proximal end;and when the syringe is positioned, the closure of the cover engages the pusher with respect to the plunger, moves the puller toward the distal end, and engages the adjustable actuator, the expandable cover;

[0019] In another embodiment, a stimulating syringe pump assembly for accommodating syringes of different sizes is provided, wherein the stimulating syringe pump assembly comprises: a base having a proximal end and a distal end, wherein the base is structured and arranged to accommodate a syringe having a plunger slidably disposed within a chamber having an outlet, wherein the chamber has a length and a diameter, and the plunger has a head; a pusher slidably coupled to the base and structured and arranged to contact the head of the plunger; a puller slidably coupled to the base; and an adjustable actuator structured and arranged to provide stimulating force between the pusher and the puller, wherein the adjustable actuator is provided by at least one spring connected between the pusher and the puller to provide a first force, and an adjustable brake structured and arranged to provide an adjustable braking force to reduce the first force, wherein the stimulating force is stimulatingly selected by adjusting the adjustable braking force applied to reduce the first force. Accordingly, when the syringe is seated on the base, sliding the puller in a distal direction causes the pusher to contact the head of the plunger and apply a substantial force, said force is sufficient to move the plunger of the syringe and distribute liquid from the chamber at a desired flow rate; and a cover pivotably connected to the proximal end of the base, wherein a linkage is pivotably connected between the cover and the puller and is structured and arranged to convert the opening of the cover into movement toward the proximal end of the puller and the pusher, and when the syringe is positioned, the closing of the cover causes the pusher to engage with the plunger, moves the puller toward the distal end, and tensions the at least one optionally attached spring. Brief explanation of the drawing

[0020] FIG. 1 is a top perspective view of a stimulating pump for different syringe sizes in a closed state according to at least one embodiment of the present invention. FIG. 2 is a top perspective view of a pump for different syringe sizes in an open state according to at least one embodiment of the present invention. FIGS. 3a to 3dd present simplified conceptual diagrams of at least one embodiment of a sizer for a power pump for different syringe sizes for determining the size of a syringe chamber according to at least one embodiment of the present invention. FIGS. 4a through 4d provide enlarged alternative perspective and front views of an adjustable actuator of a power pump for different syringe sizes shown in FIG. 1 according to at least one embodiment of the present invention. FIG. 5 is a top perspective view of a stimulating pump for different syringe sizes according to another embodiment of the present invention. FIGS. 6a and FIGS. 6aa present simplified conceptual diagrams of another embodiment of a power pump for different syringe sizes for determining the size of a syringe chamber according to at least one embodiment of the present invention. FIGS. 7a and 7b present an enlarged perspective view and a plan view of an adjustable actuator for an embodiment of a power pump for different syringe sizes shown in FIG. 5 according to at least one embodiment of the present invention. FIGS. 7c and 7d present enlarged cross-sectional plan views of an adjustable actuator for an embodiment of a power pump for different syringe sizes shown in FIG. 5. FIG. 8a is a top perspective view of a stimulating pump for different syringe sizes in an open state according to another embodiment of the present invention. FIGS. 8b through 8e provide enlarged alternating perspective and front views of an adjustable actuator of a power pump for different syringe sizes shown in FIG. 8a according to at least one embodiment of the present invention. FIG. 9a is a top perspective view of a stimulating pump for different syringe sizes in an open state according to another embodiment of the present invention. FIG. 9b presents enlarged perspective views of an adjustable actuator of a power pump for different syringe sizes shown in FIG. 9a according to at least one embodiment of the present invention. FIG. 10 presents enlarged perspective views of another adjustable actuator of a power pump for different syringe sizes according to at least one embodiment of the present invention. Figure 11 provides a flowchart of a method using a stimulant pump for different syringe sizes for infusion therapy. Specific details for implementing the invention

[0021] Before proceeding to the detailed description, it should be acknowledged that this instruction is for illustrative purposes only and is not limiting. The concepts of this specification are not limited to use or application in a specific system or method for a compact mechanical syringe pump for dispensing liquid. Accordingly, while the means described in this specification have been illustrated and described in relation to exemplary embodiments for convenience of explanation, it will be understood and acknowledged that the principles of this specification may be equally applicable to other types of systems and methods including compact mechanical syringe pumps. Furthermore, features described or illustrated in relation to one embodiment may be combined with other embodiments, and such combinations, modifications, and variations are intended to be within the scope of the invention.

[0022] The present invention is described in the following description in relation to preferred embodiments with reference to drawings in which similar numbers represent identical or similar elements. Additionally, regarding the numbering of identical or similar elements, it will be noted that preceding values ​​identify the drawing in which the element is first identified and described, for example, CFPDSS (100) is shown in FIG. 1.

[0023] Now, referring to the drawings, particularly FIG. 1, a mechanical constant force pump (Constant Force Pump For Different Syringe Sizes, hereinafter CFPDSS (100)) for dispensing a liquid, such as a therapeutic liquid, from different syringes of different sizes according to at least one embodiment of the present invention is shown. As shown, the CFPDSS (100) is in a closed position with a syringe (102) placed inside.

[0024] To facilitate the explanation of the system and method for an embodiment of CFPDSS (100), the orientation of the CFPDSS (100) shown in the drawings refers to a coordinate system having three mutually orthogonal axes as shown in FIG. 1. These axes intersect each other at the origin of the coordinate system, and the origin is chosen to be the center of the CFPDSS (100), but all axes shown in the drawings are offset from their actual positions for clarity and ease of illustration.

[0025] As previously mentioned, the CFPDSS (100) is structured and arranged to work favorably with different syringes of different sizes, and the syringe (102) is merely an example. For ease of discussion and illustration, the syringe (102) is shown both placed within the CFPDSS (100) and removed so that various elements can be easily identified.

[0026] Generally, it will be understood and recognized that a common pre-loaded syringe (102) used for infusion therapy can generally be described as having a syringe barrel (104) having a first end (106) that provides an outlet (108) suitable for being attached to or already installed on tubing suitable for administering liquid into the syringe barrel (104). Generally, this first end (106) of the syringe (102) is tapered to reduce the overall size of the syringe (102) from the diameter of the syringe barrel (104) to a diameter suitable for fluid connection with tubing.

[0027] The barrel (104) of the syringe (102) also defines the chamber (110) of the syringe (102) containing the liquid drug (indicated by dot 112) to be dispensed. The diameter (114) of the chamber (110) is generally consistent along the length (116), and in most cases, the length (116) of the chamber (110) and the diameter (114) of the chamber (110) are substantially the same as the diameter and length of the syringe barrel (104), except that the thickness of the material on which the syringe barrel (104) is formed is added. Furthermore, unless otherwise explicitly stated, for the CFPDSS (100) described herein, the diameter (114) of the barrel (104) and the diameter (114) of the chamber (110) may be used interchangeably, and likewise, the length (116) of the barrel (104) and the length (116) of the chamber (110) may also be used interchangeably.

[0028] The plunger chamber (118) is positioned at the open end (120) of the syringe barrel (104) opposite the first end (106). The plunger (122) extends rearward from the plunger chamber (118) and generally has a length approximately equal to that of the syringe barrel (104). When pressure is applied to the head (124) of the plunger (122), the plunger chamber (118) advances toward the first end (106) of the syringe (102), and the liquid (indicated by dot 112) in the syringe (102) is discharged through the outlet (108).

[0029] Generally, the syringe (102) is provided with a finger tab (126) positioned near the open end (120) of the syringe (102), allowing the user to grasp the tab with their finger and apply pressure to the head of the syringe (102) with their thumb, palm, or other hand. In other words, when the plunger seal (118) is driven into and through the syringe barrel (104) by the plunger (122), the finger tab (126) supports the syringe barrel (104).

[0030] While a finger tab (126) may be useful, it will be understood and recognized that the first end (106) of the syringe (102) may also be used as a base during the extrusion process. In some cases, a luer, such as a disc luer, may be installed on the first end (106), in which case the disc portion of the luer may serve as a base during the extrusion process. In at least one embodiment, the luer is a flared luer described in U.S. Patent 10,506,389 (titled: System and Method for Flared Luer Connector for Medical Tubing), the entire contents of which are incorporated herein by reference. In another embodiment, the lure is a tapered lure described in U.S. Provisional Application 63 / 636,368 (titled: System and Method for a Tapered Lure Connector for Medical Tubes), the entire contents of which are incorporated herein by reference.

[0031] Furthermore, in order to extrude liquid from the syringe (102), the syringe barrel (104) must be supported by some element, and the plunger (122) must also be supported. Then, a force is applied to move the plunger (122) toward the first end (106). In portable operation, the user can actually move both components, but will also understand and recognize that the first end (106) can be pushed backward toward the plunger (122), or the plunger (122) can be pushed forward toward the first end (106).

[0032] Simply put, the advantageous aspect of the CFPDSS (100) is to accommodate the syringe (102) as just described, support the first end (106) of the syringe (102) and the head (124) of the plunger (122), and then apply force between the first end (106) and the head (124) of the plunger (122) to drive the plunger seal (118) forward and extrude liquid from the syringe (102). Additionally, in at least one alternative embodiment, it will be understood and recognized that the syringe (102) is supported by a finger tab (126) instead of the first end (106). In this embodiment, when force is applied to the head (124) of the plunger (122), support by the finger tap (126) ensures that the plunger seal (118) is driven forward toward the first end (106) to extrude liquid from the syringe (102).

[0033] In at least one embodiment, the CFPDSS (100) is developed from the applicant’s prior development of a compact mechanical pump described in U.S. Patent 10,376,636, the entire contents of which are incorporated herein by reference. However, while the '636 patent specifically teaches that when attempting to place a 50 ml syringe into a pump suitable for a 20 ml syringe, the ejection ramp ejects the syringe from the pump housing when the user attempts to close the housing, the present invention advantageously accommodates syringes of different sizes.

[0034] In fact, the embodiment of CFPDSS (100) incorporates many features and elements from the applicant’s prior development of a compact mechanical pump described in the U.S. patent application.

[0035] Additionally, CFPDSS (100) incorporates many features and elements from the applicant’s prior development of a compact mechanical pump described in U.S. Patent Application 18 / 767,796 (titled: System and Method for a Constant Force Syringe Pump Accommodating Syringes of Different Sizes), the entire contents of which are incorporated herein by reference. While 18 / 767,796 describes an advantageous system and method for automatically selecting a plurality of different springs to provide appropriate force to a syringe (102), as will be understood from the following description, the present invention advantageously applies appropriate force to a syringe using an adjustable actuator that integrates a spring and an adjustable brake.

[0036] Returning to FIG. 1, in at least one embodiment, the CFPDSS (100) has a housing (128) having a distal end (130) and a proximal end (132). In at least one embodiment, the housing (128) is provided by a base (134) and a cover (136) that are hinged at the proximal end (132) to allow opening and closing. In at least one embodiment, the base (134) and the cover (136) are of a fixed size. In another embodiment, both the base (134) and the cover (136) are expandable.

[0037] In at least one embodiment of the expandable CFPDSS (100), the base (134) is provided by a first base section and a second base section, wherein the first base section is slidably coupled with the second base section so that the first base section and the second base section can slide relative to each other between a compacted position and an expanded position. Likewise, the cover (136) is provided by a first cover section and a second cover section, wherein the first cover section is slidably coupled with the second cover section so that the first cover section and the second cover section can slide relative to each other between a compacted position and an expanded position. Generally, the base (134) and the cover (136) simultaneously switch between a compacted and an expanded state. An embodiment of such a compacted / expandable base (134) and cover (136) can be inferred from the aforementioned '636 patent.

[0038] In at least one embodiment, the CFPDSS (100) also includes a damper (138) for damping the opening motion of the cover (136). In various embodiments, the damper (138) may be pivotally coupled to the base (134) and the cover (136) separately from the hinge (140), or may be integrated as part of the hinge (140). Regardless of whether it is an element separated from the hinge (140) or a part integrated into the hinge (140), in at least one embodiment, the damper (138) is selected from a viscous damper, a fluid damper, a rotational friction damper, or similar. In at least one embodiment, the hinge (140) is a unidirectional friction hinge that provides a first resistance during closing operation and a second resistance during opening operation, wherein the second resistance is greater than the first resistance. More specifically, the hinge (140) can be advantageously structured and arranged to ensure that the cover does not suddenly pop up when the CFPDSS (100) is opened.

[0039] Furthermore, in various embodiments, the CFPDSS (100) may include a latch or locking assembly (142), such as a safety latch, that automatically secures the cover (136) in a closed position on the base (134) and requires the user to operate a release device to open the cover (136).

[0040] Furthermore, in at least one embodiment, the CFPDSS (100) also includes a strap (144) to facilitate carrying, hanging, and other uses and transport of the CFPDSS (100). Furthermore, in at least one embodiment, the CFPDSS (100) provides a window (146) so that a person can observe the condition of a syringe (102) placed inside the CFPDSS (100).

[0041] Referring to FIG. 2, an embodiment of the CFPDSS (100) is now shown in an open top view, allowing at least some elements within the CFPDSS (100) to be identified that favorably allow the CFPDSS (100) to provide the correct force for a plurality of syringes of different sizes that can be placed within the CFPDSS (100).

[0042] As illustrated in FIG. 2, at least a puller (200), a pusher (202), and a collar (204) are placed within a housing (128), more specifically on a base (134). In at least one embodiment, at least the puller (200) and the pusher (202) will be understood to be engaged in a sliding manner on at least one track (206).

[0043] The adjustable actuator (208) is also structured and arranged to provide force between the pusher (202) and the puller (200). The adjustable actuator (208) is provided by at least one spring (210) and at least one adjustable brake (212). In at least one embodiment, the spring (210) is a tape spring disposed within a housing (214) placed over the pusher (202), and a first end (216) of the spring (210) is attached to the puller (200). In various embodiments, it will be understood and recognized that a plurality of springs (210) having one or more adjustable brakes (208) may be used without departing from the scope of the present invention.

[0044] Additionally, since the puller (200) has a movable linkage (218) connecting the puller (200) to the cover (136), it will be recognized that the movement of the cover (136) between the open and closed positions imparts a sliding motion of the puller (200) along the track (206) of the base (134). More specifically, when the cover (136) is lowered for closing, the linkage (218) moves the puller (200) toward the distal end (130), and when the cover (136) is raised for opening, the linkage (218) moves the puller (200) toward the proximal end (132).

[0045] For the illustrated conceptual embodiment, the cover (136) and the base are pivotally connected at one end, but an alternative embodiment may be provided in which the cover (136) slides longitudinally over the base, and a movable linkage (218) connecting the puller (200) to the cover (136) is mechanically adapted for activation through the sliding of the cover (136) between open and closed positions in the opposite direction to rotation around the hinge (140).

[0046] It will be understood and recognized that the CFPDSS (100) is advantageously structured and arranged to accommodate a plurality of different syringe sizes, for example, syringes having a volume of at least 5 milliliters to 120 milliliters, so that the CFPDSS (100) advantageously allows different forces to be applied to each of the syringes of different sizes. These different forces are provided by an adjustable actuator (208).

[0047] Simply put, it can be understood and recognized that the spring (210) and the adjustable brake (212) are associated and interact cooperatively to provide an appropriate selected force to the syringe (102) placed within the CFPDSS (100). Furthermore, the spring (210) provides a first force between the puller (200) and the pusher (202). For at least one embodiment, this first force is the maximum force that may be required of the syringe (102) placed within the CFPDSS (100). The adjustable brake (212) provides a braking force that reduces the first force of the spring (210) to the desired force required for other syringes that require less than the maximum force.

[0048] Furthermore, the desired force provided by the CFPDSS (100), more specifically by the adjustable actuator (208), is advantageously about 1 to 25 pounds of force. Thus, the CFPDSS (100) advantageously allows a suitable predetermined force appropriate to the size of the syringe chamber to be applied to the plunger of the syringe placed within the enclosure assembly, and this force can be easily changed (increased or decreased) from one syringe to the next when the syringes are of different sizes.

[0049] The adjustable brake (212) may be provided in various different mechanical forms, including but not limited to friction brakes, staged cams, pneumatic brakes, progressive brakes, disbrakes, or dampers.

[0050] Additionally, the braking force applied by the adjustable brake (212) is applied in at least two ways. In the first case, the braking force is applied directly to the spring (210) by the adjustable brake (212) to reduce the first force of the spring to a desired force. In at least the second case, the braking force can be applied to the pusher (202) to induce a drag force opposing the first force of the spring (210) as the spring (210) acts to pull the pusher (202) toward the puller (200). This drag force can be applied by increasing friction between the pusher (202) and the track(s) (206).

[0051] In various embodiments, the braking force applied by the adjustable brake (212) may be set manually or automatically. For an embodiment incorporating a system for automatically setting the adjustable brake, this may be achieved at least partially by a sizer (220), which is a device structured and arranged to automatically adjust the adjustable brake (212) according to the size of the syringe (102) placed within the CFPDSS (100).

[0052] Returning to FIG. 2, for at least one first embodiment of the CFPDSS (100), for at least one exemplary embodiment illustrated, the collar (204) is positioned in a fixed position on the base (134), but it will be understood and recognized that in at least one alternative embodiment, the collar may be engaged in a sliding manner on a track provided by the base (134).

[0053] For accommodating different syringes (102) having different barrel diameters, in at least one embodiment, the collar (204) may be provided by two lateral elements that can be adjusted outward or inward by a user to firmly grip the syringe barrel (104). Various alternatives, including but not limited to conformal materials that compress or expand according to the diameter of the syringe barrel (104), may also be used to accommodate the collar (204) so ​​that it firmly / tightly grips the syringe barrel (104) and / or provides a brace support for the finger tab of the syringe (102).

[0054] For ease of discussion, the syringe (102) is depicted as being placed within the CFPDSS (100). More specifically, the finger tab at the open end of the syringe barrel (104) is depicted as being coupled with the collar (204), and the first end (106) of the syringe (102) is depicted as being seated on the selector (222).

[0055] The selector (222) is selectively movable between multiple positions, and for at least one embodiment, these positions correspond to various and distinctly different barrel lengths of a 50ml syringe (102), a 20ml syringe (102), a 10ml syringe (102), and a 5ml syringe (102).

[0056] For at least one embodiment, a spring (not shown) may deflect the selector (222) so that it is positioned close to the collar (204). When the selected syringe (102) is placed in the CFPDSS (100) — the first end (106) of the syringe (102) is partially placed within the sheet (224) provided by the selector (222). When the syringe (102) is lowered so that the finger tab (126) engages with the collar (204), the selector (222) slides from the collar (204) to a separate position appropriate for the size of the syringe (102).

[0057] As mentioned above, for various embodiments in which a syringe is connected to a luer, such as a flared luer as described in U.S. Patent 10,500,389 titled "SYSTEM AND METHOD FOR FLARED LUER CONNECTOR FOR MEDICAL TUBING" or a tapered luer as described in U.S. Provisional Application 63 / 616,368 titled "SYSTEM AND METHOD FOR A TAPERED LURE CONNECTOR FOR MEDICAL TUBING," the selector (222), more specifically the seat (224) of the selector, may be structured and arranged as an accepting base for such a tapered or flared luer. Simply put, the sheet (224) can be structured and arranged to receive a compliant lure and discharge a non-compliant lure.

[0058] For this present exemplary embodiment, the size of the syringe (102) is determined by the length (116) of the syringe (102), more specifically by the length (116) of the syringe barrel (104) / chamber (110). In this embodiment, it will be understood and recognized that the collar (204) receiving the finger tab (126) supports them and provides a brace for the syringe (102) as would be the finger of a human operator. For another embodiment, both the collar (204) and the selector (222) provide a brace for the syringe barrel (104).

[0059] For at least one embodiment, it will be understood and recognized that a selector (222) providing support for the syringe (102) in place of the collar (204) may be provided. Furthermore, for at least one embodiment, each distinct position has a binder (222) that allows the selector (222) to be temporarily fixed to the base (134) at that position when it is slid to a desired position. For at least one embodiment, the binder is provided by notches of the base (134) and ridges extending from the selector (222). When the selector (222) is grasped and tilted slightly upward, the ridges are removed from the notches and the selector (222) can be moved to a new position. When repositioned, the selector (222) is pressed down and the ridges are then pressed into the corresponding notches, remaining in the selected position until the selector (222) is tilted upward once again to remove the ridges from the notches.

[0060] In at least one embodiment, the selector (222) is structured and arranged to determine the size of the syringe (102) placed within the CFPDSS (100), and more specifically, is a component of the sizer (220) seated between the selector (222) and the collar (204). In at least one embodiment, the sizer (220) is a mechanical system provided at least partially by at least one linkage, gear, control rod, or bar that mechanically interconnects the selector (222) and the selector (222) with the adjustable actuator (208), more specifically the adjustable brake (212).

[0061] For the embodiment illustrated in FIG. 2, in relation to interconnecting the selector (222) with the adjustable brake (212), the selected position of the selector (222) mechanically triggers one or more controllers (226) to engage one or more brake pins (228) of the adjustable brake (212). It will be understood and recognized that one or more controllers (226) may be further described as a control rod / gear / bar / cable or other element capable of interconnecting the selector (222) and the adjustable brake (212).

[0062] In fact, each of the one or more controllers (226) may be further described as a lever having a lower section and a higher section, including but not limited to control rod(s) / bar(s). When the selector (222) slides longitudinally within the housing (128) along one or more tracks (206), the one or more control rod(s) / bar(s) / lever(s) (226) may slide a sufficient distance for the lower section to switch to the higher section, and the higher section activates the selection of the associated brake pin (228).

[0063] In fact, it will be understood and recognized that the mechanical determination of the size of the syringe (102) is determined by the movement toward the distal end (130) of the selector (222) when the syringe (102) is placed within the CFPDSS (100) in at least one embodiment. More specifically, the user places the first end (106) of the syringe (102) into the seat (224) of the selector (222) and presses the selector (222) toward the distal end (130) to bring the finger tab (126) to a position where it is placed within the collar (204). The longitudinal movement of the selector (222) within the housing (128) along the base (134) triggers one or more control rod(s) / bar(s) / lever(s) to selectively engage one or more brake pins (228), which provides a drag force to the pusher (202).

[0064] When the cover (136) is closed, the linkage (218) connected between the cover (136) and the puller (200) acts to drive the puller (200) along the track(s) (212) of the base (134) toward the collar (204) and the distal end (130). As this sliding movement occurs, each engaged brake pin (228) provides a drag force to the pusher (202) as the spring (210) pulls the pusher (202) toward the puller (200), and said drag force reduces the effective first force of the spring to achieve a constant force appropriate for the size of the syringe placed within the CFPDSS (100).

[0065] When the cover (136) is closed, the puller (200) will be substantially held in place by the linkage (218), so the pusher (202) will slide toward the puller (200). As can be seen in FIG. 2, the pusher (202) has a plunger receiver (230) structured and arranged to contact the head (124) of the plunger (122). In at least one embodiment, the plunger receiver (230) is not merely in contact, but engages with the head (124) of the plunger (122), such as by providing a seat or base that can help center the plunger (122) and prevent slide slippage that may occur when force is applied to the plunger (122).

[0066] The locking assembly (142) can be more fully understood in FIG. 2. More specifically, in at least one embodiment, the locking assembly (142) is provided by an engaging tooth (232) provided at the distal end (130) and a corresponding tooth (234) on the cover, and the plate (236) is biased inward by a spring (not shown), and the user pulls the plate outward with a finger to release the teeth (232 and 234) and open the cover (136). As mentioned above, the hinge (140) may be a unidirectional friction hinge that advantageously delays the opening of the cover (136).

[0067] The first force of the spring (210), which is offset by the braking force provided by the engaged brake pin (228), results in a predetermined force pulling the pusher (202) toward the puller (200), and this predetermined force is applied particularly to the plunger (122)—pushing it into the syringe barrel (104) and extruding liquid from the outlet (108) of the first end (106).

[0068] Furthermore, the sizer (220) provided by an exemplary embodiment of the selected engagement of the selector (222), the control rod(s) / bar(s) / lever(s) (226) and the first end (216) of one or more tape springs (210) advantageously ensures that the force provided by the dual tape springs (210) is a predetermined force suitable for the size of the syringe (102) placed within the CFPDSS (100).

[0069] This mechanical selection of the brake pin (228) as an element of the adjustable brake (212) can be more fully understood in relation to the conceptual illustration presented in FIGS. 3a through 3cc. For ease of illustration and discussion, the CFPDSS (100) has been reduced to a simplified form for demonstration purposes. The spring (210) is placed on the pusher (202), and the first end of the spring (210) is connected to the puller (200), and the control rod / lever (200) corresponding to the control rod / lever (226) is also illustrated.

[0070] In each of FIGS. 3a through 3dd, a top view (Fig. 3a, Fig. 3b, Fig. 3c and Fig. 3d) of a simplified CFPDSS (100) is shown at the top of the drawing page, and a corresponding perspective view (Fig. 3aa, Fig. 3bb, Fig. 3cc and Fig. 3dd) of the simplified CFPDSS (100) is shown at the bottom. In the middle of these top and perspective views, a reference view of a control rod (226), identified as a control rod (300A, 300B and 300C) for the present illustrations, is shown.

[0071] In each reference drawing, each control rod (300), more specifically the control rods (300A, 300B, and 300C), is understood to have a lower section (302A, 302B, and 302C) and a higher section (304A, 304B, and 304C). As can be seen from the reference drawings, each control rod (300) has a different profile because each has a higher section (304) having a different length.

[0072] Additionally, the control rod (300A) is illustrated as having a folding slide arrangement in which a portion of the lower section (302A) slides into a portion of the control rod (300A) providing the high section (304A). Of course, it will be understood and recognized that this arrangement may be reversed in an alternative embodiment, where the portion of the control rod (300A) providing the high section (304A) slides into a portion of the control rod (300A) providing the low section.

[0073] In any arrangement, it will be understood and recognized that these alternative embodiments of the control load (300) will be incorporated into the alternative embodiments mentioned above, wherein the base (134) and cover (136) are also configured to have a sliding arrangement, such as between a compact state for storage and an extended configuration state for use.

[0074] In FIGS. 3a and 3aa, the system is in a stationary state and the brake pin (228) is not engaged. FIGS. 3b and 3bb, FIGS. 3c and 3cc, and FIGS. 3d and 3dd each illustrate how different syringes of different lengths mechanically trigger different engagements of the brake pin (228).

[0075] In FIGS. 3b through 3bb, conceptualizing the insertion of a syringe (102) having a first length, the selector (222) moves away from the spring (210) and advances longitudinally toward the distal end (130) of the base (134), and thus the control rod / lever (300) also moves toward the distal end (130). As a result, the control rod / lever (300A) moves to switch to a high section (304A) below the brake pin (228A), which now engages with the pusher (202).

[0076] In FIG. 3c to FIG. 3cc, conceptualizing the insertion of a syringe (102) having a second length, the selector (222) is further advanced toward the distal end (130) of the base (134), and thus the control rod / lever (300) is also moved toward the distal end (130). As a result, in addition to the control rod / lever (300A) engaging the brake pin (228A), the control rod / lever (300B) is also moved to transition to the high section (304B) below the brake pin (228B), which now engages with the pusher (202).

[0077] Continuing with the example, FIGS. 3d through 3dd conceptualize the insertion of a syringe (102) having a third length, and the selector (222) is advanced much further toward the distal end (130) of the base (134), and thus the control rod / lever (300) is also moved further toward the distal end (130). As a result, the control rod / lever (300C) is also moved longitudinally and switched to a high section (304C) below the brake pin (228C), which now engages with the pusher (202) in addition to the brake pin (228A) and brake pin (228B).

[0078] For ease of illustration, conceptual illustrations have been rendered to show the engagement of the brake pins (228), but it will be understood and recognized that the initial state can be reversed, namely that in the stationary state, all brake pins (228) are initially engaged, and when a larger or longer syringe (102) is subsequently inserted, the brake pins (228) are optionally released.

[0079] FIGS. 4a through 4d present enlarged cross-section perspective and side views of the control rod / lever (226) and brake pin (228) in a stationary and engaged state. It can also be understood that the first end of the spring (210) is permanently attached to the puller (200), and the housing (214) of the spring (210) is attached to the pusher (202). Since the spring (210) is directly connected between the pusher (202) and the puller (200), it will be understood and recognized that the first force of the spring will be applied as a retractive force when the pusher (202) and the puller (200) are positioned apart from each other. Adjustment of this first force is advantageously achieved by a braking force that can be regulated by the adjustable brake (212). In FIGS. 4a to 4d, the integration of a brake pin (228) as an element of an adjustable brake (212), more specifically a pusher (202), can be more fully understood.

[0080] More specifically, in FIG. 4a showing a perspective view and FIG. 4b showing a side view, the CFPDSS (100) does not accommodate a syringe (102) having a length sufficient to trigger a control rod / lever (226A / 300A) for transitioning from a lower section (302A) below the brake pin (228A) to a higher section (304A) to lift the brake pin (228A), and the spring (400A) is extended. However, the brake pin (228B) is lifted, indicating that the length of the accommodated syringe is sufficient to trigger its control rod / lever (not shown in FIG. 4a and 4b—see FIG. 4c and 4d), and the associated spring (400B) is now compressed.

[0081] In FIG. 4c, which presents a perspective view, and FIG. 4d, which presents a side view, the control rod / lever (226B) is now shown, and it can be seen that the high section (304A) is positioned below the brake pin (228B), so that the brake pin (228A) moves vertically upward to compress the spring (400A). In at least one embodiment, the rider pin (402B) is positioned through the distal end of the brake pin (228), and as the brake pin (228A) is now lifted, the cover is closed and the linkage (218) (see FIG. 4b and FIG. 4d) will move along the brake rail (404B and 404BB) as it advances the puller toward the distal end (130) (not shown in FIG. 4a through FIG. 4d). When the spring (400A) attempts to extend, it provides force through the brake pin (228B), and the friction between the rider pin (402B) and the brake rail (404B) provides an adjustable braking force that provides resistance to the first force of the spring (210) to achieve the appropriate desired force on the received syringe (102).

[0082] FIGS. 2 through 4d conceptually present at least one embodiment in which an adjustable brake (212) is structured and arranged to provide braking force indirectly to a spring (210). FIGS. 5 through 8e conceptually present at least one alternative embodiment in which an adjustable brake (212) is structured and arranged to provide braking force directly to a spring (210).

[0083] More specifically, FIG. 5 shows a top perspective view of an open alternative embodiment of the CFPDSS (100). As illustrated, this embodiment of the CFPDSS (100) shares essentially the same core components as described above for the CFPDSS (100) illustrated in FIG. 2, except for the notable exception of having a different adjustable brake (212).

[0084] In the alternative embodiment illustrated in FIG. 5, the selector (222) is coupled to the adjustable brake (212) by a controller that can be more clearly understood as a gear rail (500). As the selector (222) moves toward the distal end (130) and away from the distal end, the gear rail (500) moves longitudinally under the puller (200) and pusher (202). As illustrated, the gear rail (500) engages with an adjustable gear (502) positioned through the side wall of the housing (214) of the spring (210). More specifically, the longitudinal movement of the gear rail (500) is converted into rotational movement of the adjustable gear (502), which in turn causes movement of an internal cam (not illustrated) to apply friction to the spring (210) or release friction from the spring (210).

[0085] The concept of such an adjustable brake is conceptually illustrated in FIGS. 6a and FIGS. 6aa. As with FIGS. 3a through 3dd, the CFPDSS (100) has been greatly simplified for demonstration purposes. FIG. 3a provides a top view and FIG. 3aa provides a corresponding perspective view. The spring (210) is shown disposed within a housing (214) fixed to the pusher (202). The first end (216) of the spring is attached to the puller (200).

[0086] As the selector (222) moves longitudinally toward or away from the distal end (130), the gear rail (500) passes under the adjustment gear (502), and the longitudinal movement (600) of the gear rail (500) is converted into a rotational motion (602) of the adjustment gear (502). In at least one embodiment, this rotational motion (602) may be used to rotate the cam downward relative to the spring (210) in the housing (214) (providing an increase in the applied adjustment braking force) or to rotate it upward away from the spring (210) in the housing (214) (providing a decrease in the applied adjustment braking force).

[0087] In another embodiment, the adjustment gear can increase the adjustable braking force by driving a disc brake (not shown) against the spring again, or decrease the adjustable braking force by moving it away from the spring.

[0088] FIG. 7a provides an enlarged partial perspective view of an adjustable actuator (214), more specifically showing a gear rail (500) that passes under and engages with an adjustable gear (502), and FIG. 7b also provides a general side view.

[0089] FIGS. 7c and 7d provide cross-sectional views of an adjustable actuator (208) and further show an adjustable cam (700) driven by an adjustable gear (502). In FIG. 7c, it can be seen that the cam (700) is rotated downward to engage with the spring (210), thereby applying an adjustable braking force to the spring (210). In FIG. 7d, it can be seen that the cam (700) is rotated to substantially disengage from the spring (210), thereby adjusting to apply less braking force to the spring (210).

[0090] Furthermore, it will be understood and recognized that by changing the degree of contact between the cam (700) and the spring (210), an adjustable amount of braking force is applied directly to the spring (210) to achieve a desired substantially stable force suitable for the syringe (102) placed within the CFPDSS (100).

[0091] In relation to FIGS. 2 through 7d discussed above, it will be understood and recognized that in these illustrated embodiments, the CFPDSS (100) automatically determines and adjusts the braking force of the adjustable actuator (208) by determining the size of the syringe.

[0092] It will be understood and recognized that the advantage of CFPDSS (100) for accommodating syringes of different sizes requiring substantially different forces for extrusion is not strictly limited to self-determining devices.

[0093] In fact, FIGS. 8a through 8e illustrate another alternative embodiment comprising an adjustable actuator that is manually adjustable. More specifically, FIG. 8a illustrates a top perspective view of an open alternative embodiment of the CFPDSS (100). As illustrated, this embodiment of the CFPDSS (100) shares essentially the same core components described above with respect to the CFPDSS (100) device illustrated and described above with respect to FIGS. 2 and FIGS. 5, except for the notable exception of having a different adjustable brake (212).

[0094] In this case, it is a manually operated adjustable brake (212). As illustrated, the adjustable brake (212) provides a knob (800) having an indicator (802). In at least one embodiment, the indicator (802) is a visual indicator. In at least one alternative embodiment, the indicator (802) may be a tactile indicator.

[0095] In at least one embodiment, a visual indicator (802) is provided to indicate the size of the syringe, e.g., a 50 ml syringe, a 20 ml syringe, a 10 ml syringe, or a 5 ml syringe. In at least one other embodiment, the visual indicator (802) indicates the degree or percentage of the applied braking force. Of course, it can be understood and recognized that the visual indicator (802) may be a mapping—"A" for syringe "A", "B" for syringe "B", "C" for syringe "C", etc.—each syringe is identified by a number, letter, symbol, or shape that may be more easily recognized by some users than a milliliter indication. Furthermore, in at least one embodiment, the adjustable braking force is selected by selecting a predefined setting for the adjustable brake (212).

[0096] In another embodiment, the adjustable brake (212) may be completely variable. In this embodiment, the CFPDSS (100) may be provided with or coupled to a flow rate indicator, and the braking force is selected by adjusting the adjustable brake (212) to a desired flow rate indicated by the flow rate indicator.

[0097] FIG. 8b is an enlarged cross-sectional view through the adjustable brake (212) shown in FIG. 8a, and FIG. 8c provides an enlarged general cross-sectional view of the same. In both FIG. 8b and FIG. 8c, it can be seen that the knob (800) has a threaded shaft (804) passing through a threaded mount (806). In FIG. 8b and FIG. 8c, the knob (800) is in an initial position where the threaded shaft (804) is not rotated sufficiently to bring the distal end (808) of the threaded shaft (804) into contact with the spring (210).

[0098] FIG. 8d is an enlarged cross-sectional view through the adjustable brake (212) shown in FIG. 8, and FIG. 8e provides an enlarged general cross-sectional view of the same. In these drawings, it will be understood and recognized that the knob (800) has been rotated to drive the threaded shaft (804) through the mount (806), and that by doing so, the distal end (808) of the threaded shaft (804) is now in contact with the spring (210) and is applying an adjustable braking force directly to the spring (210).

[0099] In at least one embodiment, the distal end (808) of the threaded shaft (804) is made of a semi-compliant / semi-resilient material, which will deform relative to the spring (210) to increase the contact surface area between the distal end (808) and the spring (210), thereby further allowing for the adjustment of the applied adjustable braking force.

[0100] FIG. 9a shows an alternative embodiment of a CFPDSS (100) having a manually operated adjustable brake (212). FIG. 9b shows an enlarged perspective cross-sectional view of the illustrated embodiment. In FIG. 9a, as with the embodiments illustrated in FIG. 8a through 8d, the adjustable brake is again a knob (900) having an indicator (902) on a threaded shaft (904), but as with the embodiment of FIG. 1a, the adjustable braking force is applied to a pusher (202) to create frictional drag between the pusher (202) and the rail or base (134) on which the pusher (202) slides.

[0101] As can be more fully understood in FIG. 9b, in at least one embodiment, the distal end (906) of the threaded shaft (904) is made of a semi-compliant / semi-elastic material, so that it will deform relative to the rail or base (134) to increase the contact surface area between the distal end (906) and the rail or base (134), thereby further allowing for the adjustment of the applied adjustable braking force.

[0102] FIG. 10 shows another embodiment of the CFPDSS (100). In this embodiment, the adjustable actuator (208) includes an adjustable brake (212) which is a pneumatic piston (1000), and the inflow or outflow of air is controlled by an adjustable valve operated by a knob (1002).

[0103] In relation to the embodiments illustrated in FIGS. 8a through 10 as manually operated adjustable brakes, it will be understood and recognized that variations of each embodiment can be automated by using a sizer (220) with a selector (222) and by modifying a variation of the control linkage / rod / lever (226) as illustrated and described above.

[0104] In relation to the above description, it may be recognized that at least one embodiment of a CFPDSS (100) accommodating syringes (102) of different sizes can be summarized as follows: a base (134) having a proximal end (132) and a distal end (132), wherein the base (134) is structured and arranged to accommodate a syringe (102) having a plunger (122) slidably disposed within a chamber (110) having an outlet (108), wherein the chamber (110) has a length (116) and a diameter (114), and wherein the plunger (122) has a head (124); a pusher (202) slidably coupled to the base (134), wherein the pusher (202) is structured and arranged to contact the head (124) of the plunger (122); A puller (200) slidingly coupled with the base (134); an adjustable actuator (208) structured and arranged to provide a force between the pusher (202) and the puller (200); wherein the adjustable actuator (208) is connected between the pusher (202) and the puller (200) and is provided by a spring (210) that provides a first force and an adjustable brake (212) structured and arranged to provide an adjustable braking force to reduce the first force, and wherein the force is adjustablely selected by adjusting the adjustable braking force applied to reduce the first force. Accordingly, when the syringe (102) is seated on the base (134), moving the puller (200) in a sliding manner in the distal direction causes the pusher (202) to come into contact with the head (124) of the plunger (122) and apply substantial force, and the force is sufficient to move the plunger (122) of the syringe (102) and distribute liquid from the chamber (110) at a desired flow rate;and a cover (136) connected to the base (134), wherein a linkage (218) is pivotally coupled between the cover (136) and the pusher (202) and is structured and arranged to convert the opening of the cover (136) into the movement of the puller (200) and the pusher (202) toward the proximal end (132), and when the syringe (102) is placed, closing the cover (136) causes the pusher (202) to be coupled to the plunger (122), moves the puller (200) toward the distal end (132), and engages the adjustable actuator (208).

[0105] Another embodiment of the CFPDSS (100) can be summarized as follows: an expandable base (134) having a proximal end (132) and a distal end (132), wherein the base (134) comprises a first base (134) section and a second base (134) section, wherein the first base (134) section is slidably coupled with the second base (134) section so that the first base (134) section and the second base (134) section can slide relative to each other between a compression position and an expansion position, wherein the base (134) in the expansion position is adapted to accommodate a syringe (102) having a plunger (122) slidably disposed within a chamber (110) having an outlet (108), wherein the chamber (110) has a length (116) and a diameter (114), and the plunger (122) has a head (124). A base (134); a pusher (202) that slides into the base (134), wherein the pusher (202) is dimensionally sized to contact the head (124) of the plunger (122); a puller (200) that slides into the base (134); and an adjustable actuator (208) structured and arranged to provide a force between the pusher (202) and the puller (200), wherein the adjustable actuator (208) is provided by a spring (210) connected between the pusher (202) and the puller (200) and providing a first force, and an adjustable brake (212) structured and arranged to provide an adjustable braking force to reduce the first force, wherein the force is regulated by adjusting the adjustable braking force applied to reduce the first force.Accordingly, when the syringe (102) is seated on the base (134), moving the puller (200) in a sliding manner in the distal direction causes the pusher (202) to come into contact with the head (124) of the plunger (122) and apply substantial force, and the force is sufficient to move the plunger (122) of the syringe (102) and distribute liquid from the chamber (110) at a desired flow rate; and an expandable cover (136) pivotally coupled to a proximal end (132) of the base (134), wherein a linkage is pivotally coupled between the cover (136) and the puller (200) and is structured and arranged to convert the opening of the cover (136) into the movement of the puller (200) and the pusher (202) toward the proximal end (132), and when the syringe (102) is placed, closing the cover (136) causes the pusher (202) to be coupled to the plunger (122), moves the puller (200) toward the distal end (132), and couples the adjustable actuator (208); the expandable cover (136) is included.;

[0106] Furthermore, another embodiment of the CFPDSS (100) can be summarized as follows: a base (134) having a proximal end (132) and a distal end (132), wherein the base (134) is structured and arranged to accommodate a syringe (102) having a plunger (122) slidably disposed within a chamber (110) having an outlet (108), wherein the chamber (110) has a length (116) and a diameter (114), and the plunger (122) has a head (124); a pusher (202) slidably coupled to the base (134), wherein the pusher (202) is structured and arranged to contact the head (124) of the plunger (122); and a puller (200) slidably coupled to the base (134). An adjustable actuator (208) structured and arranged to provide a force between the pusher (202) and the puller (200), wherein the adjustable actuator (208) is connected between the pusher (202) and the puller (200) and is provided by a spring (210) that provides a first force and an adjustable brake (212) structured and arranged to provide an adjustable braking force to reduce the first force, wherein the force is adjustablely selected by adjusting the adjustable braking force applied to reduce the first force; Accordingly, when the syringe (102) is seated on the base (134), moving the puller (200) in a sliding manner in the distal direction causes the pusher (202) to come into contact with the head (124) of the plunger (122) and apply substantial force, and the force is sufficient to move the plunger (122) of the syringe (102) and distribute liquid from the chamber (110) at a desired flow rate;and a cover (136) pivotally connected to a proximal end (132) of the base (134), wherein a linkage is pivotally coupled between the cover (136) and the puller (200) and is structured and arranged to convert the opening of the cover (136) into the movement of the puller (200) and the pusher (202) toward the proximal end (132), and when the syringe (102) is placed, closing the cover (136) causes the pusher (202) to engage the plunger (122), moves the puller (200) toward the distal end (132), and tensions the spring (210) to apply force to the plunger (122) of the syringe (102); the cover (136) is included.

[0107] Since embodiments of CFPDSS (100) have been described, other embodiments relating to at least one method of using CFPDSS (100) to provide an injection therapy into subcutaneous tissue will now be discussed. It will be recognized that the described methods do not need to be performed in the order described herein, but that these descriptions are merely examples of methods of providing and using CFPDSS (100).

[0108] KORU Medical Systems, Inc. of Mahwah, New Jersey, is and continues to be a pioneer in the field of infusion pump technology, needle set technology, and flow control fluid technology using specifically machined flow control tubing. Indeed, KORU has recognized that different flow rates can be provided by operating with different flow combinations of flow control tubing, such as the systems and methods disclosed in U.S. Patent 10,420,886 titled “MULTI-FLOW UNIVERSAL TUBING SET,” which is incorporated herein by reference, and U.S. Patent 10,709,839 titled “PRECISION VARIABLE FLOW RATE INFUSION SYSTEM AND METHOD,” which is incorporated herein by reference.

[0109] Furthermore, KORU has developed an advantageous infusion system that allows high flow rates at low pressure, as disclosed in U.S. Application 17 / 729,914 disclosed as U.S. Published Patent No. 2022 / 0265923 titled “HIGH FLOW AT LOW PRESSURE INFUSION SYSTEM,” by reference herein. Furthermore, for at least one embodiment, the needle(s) used in the infusion therapy may be a snap-in needle structure shown and described in U.S. Patent Application 18 / 216,342 titled “SYSTEM AND METHOD FOR BUTTERFLY NEEDLE ASSEMBLY,” by reference herein.

[0110] Additionally, it will be understood and recognized that CFPDSS (100) can function as a pump for infusion therapy provided to a patient incorporating one or more of the identified technologies. Additionally, as mentioned above, for various embodiments where a syringe is coupled to a lure, for example, in the case of a lure such as the flared lure disclosed in U.S. Patent No. 10,506,389 titled “SYSTEM AND METHOD FOR FLARED LUER CONNECTOR FOR MEDICAL TUBING” or the tapered lure disclosed in U.S. Provisional Application No. 63 / 616,342 titled “SYSTEM AND METHOD FOR A TAPERED LURE CONNECTOR FOR MEDICAL TUBING” which is referenced by reference in this specification, the selector (222), and more specifically the seat (224) of the selector, may be structured and arranged as a receiving base for such tapered or flared lure.

[0111] Referring to FIG. 11, a flowchart for at least one method (1100) of using CFPDSS (100) for infusion therapy is presented. Generally, the method (1100) begins by providing CFPDSS (100) and is a block (1102).

[0112] The cover (136) of the CFPDSS (100) is then opened and is a block (1104). A selected syringe is then placed inside the CFPDSS (100). As discussed above, the CFPDSS (100) is structured and arranged to use a sizer (220) to determine the size of the placed syringe (102) and to mechanically engage an adjustable actuator (208) to provide a predetermined force suitable for the placed syringe, and is a block (1106).

[0113] In order to fully bind the CFPDSS (100) with a predetermined force, the cover (136) of the CFPDSS (100) is then closed, the infusion process is initiated for the patient, and block (1108). It will be understood and recognized that because the CFPDSS (100) is structured and arranged advantageously to determine the size of the syringe and then determine a predetermined force for the syringe based on the determined size, the same CFPDSS (100) can be used for the treatment of infusion therapy with syringes of different sizes without adverse effects caused by inappropriate force applied to the administration. Furthermore, a single CFPDSS (100) has the advantage of being able to independently determine different syringe sizes and automatically select a predetermined force suitable for the administration of the drug within the syringe of the determined size.

[0114] Modifications to the above method, system, and structure may be made without departing from the scope of the invention. Accordingly, it should be noted that the description and / or the contents depicted in the accompanying drawings should be interpreted as exemplary and not as restrictive. In practice, as will be obvious to a person skilled in the art, many other embodiments may and are possible. The following claims are limited by, but are not limited to, the embodiments discussed herein, but only by their terms and equivalents.

Claims

Claim 1 A constant force syringe pump assembly for accommodating syringes of different sizes, comprising: a base having a proximal end and a distal end, wherein the base is structured and arranged to accommodate a syringe having a plunger slidably disposed within a chamber having an outlet, wherein the chamber has a length and a diameter, and the plunger has a head; a pusher slidably coupled to the base, wherein the pusher is structured and arranged to contact the head of the plunger; a puller slidably coupled to the base; an adjustable actuator structured and arranged to provide a constant force between the pusher and the puller, wherein the adjustable actuator is provided by at least one spring connected between the pusher and the puller and providing a first force, and an adjustable brake structured and arranged to provide an adjustable braking force to reduce the first force, wherein the constant force is slidably selected by adjusting the adjustable braking force applied to reduce the first force; and accordingly, the syringe A force syringe pump assembly comprising: a puller that slides in a distal direction when seated on the base, causing the pusher to contact the head of the plunger and apply force, the force being sufficient to move the plunger of the syringe and distribute liquid from the chamber at a desired flow rate; and a cover connected to the base, wherein a linkage is formed between the cover and the puller and is structured and arranged to convert the opening of the cover into movement of the puller and pusher toward the proximal end, and when the syringe is positioned, the closing of the cover causes the pusher to engage with the plunger, moves the puller toward the distal end, and engages the adjustable actuator. Claim 2 A stimulating syringe pump assembly according to claim 1, wherein the adjustable brake is associated with the at least one spring, and the adjustable brake provides the adjustable braking force to the at least one spring. Claim 3 A stimulating syringe pump assembly according to claim 1, wherein the adjustable brake is associated with the pusher, and the adjustable brake provides the adjustable braking force to the pusher. Claim 4 A syringe pump assembly according to claim 1, wherein the adjustable braking force is selected by selecting a predefined setting for the adjustable brake. Claim 5 A force syringe pump assembly according to claim 1, wherein the adjustable braking force is user-modifiable to increase or decrease the force applied to the head of the plunger. Claim 6 A power syringe pump assembly according to claim 1, wherein the power pump has a flow rate indicator, and the braking force is selected by adjusting the adjustable brake to a desired flow rate indicated by the flow rate indicator. Claim 7 A pressure syringe pump assembly according to claim 1, wherein the adjustable braking force is selected by a sizer and a selector, which are at least partially provided by at least one controller associated with the adjustable braking force, and the selector is movable between a first position and a second position to set the size of the chamber, and the sliding of the selector from the first position to the second position causes the controller to adjust the adjustable braking force for the at least one spring to provide a pressure specific to the size of the chamber. Claim 8 A stimulating syringe pump assembly according to claim 1, wherein the cover is connected to the base by a unidirectional friction hinge, the unidirectional friction hinge provides a first resistance in a closed operation and a second resistance in an open operation, the second resistance being greater than the first resistance. Claim 9 A stamina syringe pump assembly according to claim 1, wherein the pump has a safety latch, automatically engages the base and the cover when the cover is closed, and requires the user to activate release to open the cover. Claim 10 A stamina syringe pump assembly according to claim 1, wherein the stamina provided by the adjustable actuator is a force of about 1 to 25 pounds. Claim 11 A stimulating syringe pump assembly according to claim 1, wherein the pump is structured and arranged to accommodate a syringe having a volume of at least 5 milliliters and no more than 120 milliliters. Claim 12 In paragraph 1, the adjustable brake is a friction brake, forming a tension syringe pump assembly. Claim 13 In paragraph 1, the adjustable brake is a pneumatic brake, forming a power syringe pump assembly. Claim 14 In paragraph 1, the adjustable brake is a disc brake, in a stimulating syringe pump assembly. Claim 15 In claim 1, the adjustable brake is a damper, forming a power syringe pump assembly. Claim 16 In claim 1, the pump is a stimulating syringe pump assembly having an adjustable carrying strap. Claim 17 A stimulating syringe pump assembly for accommodating syringes of different sizes, comprising an expandable base having a proximal end and a distal end, wherein the base comprises a first base section and a second base section, wherein the first base section is slidably coupled to the second base section so that the first base section and the second base section can slide relative to each other between a compression position and an expansion position, and wherein the base in the expansion position is adapted to accommodate a syringe having a plunger slidably disposed within a chamber having an outlet, wherein the chamber has a length and a diameter, and the plunger has a head; the expandable base; a pusher slidably coupled to the base and dimensioned to contact the head of the plunger; and a puller slidably coupled to the base. A controllable actuator structured and arranged to provide a force between the pusher and the puller, wherein the controllable actuator is provided by at least one spring connected between the pusher and the puller to provide a first force and a controllable brake structured and arranged to provide a controllable braking force to reduce the first force, wherein the controllable actuator is selected controllably by adjusting the controllable braking force applied to reduce the first force; accordingly, when the syringe is seated on the base, sliding the puller in a distal direction causes the pusher to contact the head of the plunger and apply a substantial force, and the force is sufficient to move the plunger of the syringe and dispense liquid from the chamber at a desired flow rate; and an expandable cover pivotally connected to the proximal end of the base, wherein a linkage is pivotally connected between the cover and the puller and is structured and arranged to convert the opening of the cover into movement of the puller and the pusher toward the proximal end;A stimulating syringe pump assembly comprising: an expandable cover, wherein when the syringe is positioned, the closure of the cover engages the pusher with respect to the plunger, moves the puller toward the distal end, and engages the adjustable actuator. Claim 18 In paragraph 17, the adjustable brake is associated with at least one spring, and the adjustable brake provides the adjustable braking force to the at least one spring, a strength syringe pump assembly. Claim 19 In paragraph 17, the adjustable brake is associated with the pusher, and the adjustable brake provides the adjustable braking force to the pusher, a strength syringe pump assembly. Claim 20 In paragraph 17, the adjustable braking force is selected by selecting a predefined setting for the adjustable brake, in a syringe pump assembly. Claim 21 In claim 17, the adjustable braking force is a user-modifiable syringe pump assembly to increase or decrease the force applied to the head of the plunger. Claim 22 In paragraph 17, the stamina syringe pump assembly, wherein the stamina provided by the adjustable actuator is a force of about 1 to 25 pounds. Claim 23 In claim 17, the pump is a stimulating syringe pump assembly structured and arranged to accommodate a syringe having a volume of at least 5 milliliters and no more than 120 milliliters. Claim 24 A power syringe pump assembly according to claim 17, wherein the power pump has a flow indicator, and the braking force is selected by adjusting the adjustable brake to a desired flow rate indicated by the flow indicator. Claim 25 In claim 17, the adjustable braking force is selected by a sizer and a selector, which are at least partially provided by at least one controller associated with the adjustable braking force, wherein the selector is movable between a first position and a second position to set the size of the chamber, and the sliding of the selector from the first position to the second position causes the controller to adjust the adjustable braking force for the at least one spring to provide a specific force for the size of the chamber, a force syringe pump assembly. Claim 26 In claim 17, the cover is connected to the base by a unidirectional friction hinge, the unidirectional friction hinge provides a first resistance in a closed operation and a second resistance in an open operation, the second resistance being greater than the first resistance, a stimulating syringe pump assembly. Claim 27 A pressure syringe pump assembly for accommodating syringes of different sizes, comprising: a base having a proximal end and a distal end, wherein the base is structured and arranged to accommodate a syringe having a plunger slidably disposed within a chamber having an outlet, wherein the chamber has a length and a diameter, and the plunger has a head; a pusher slidably coupled to the base and structured and arranged to contact the head of the plunger; a puller slidably coupled to the base; an adjustable actuator structured and arranged to provide pressure between the pusher and the puller, wherein the adjustable actuator is provided by at least one spring connected between the pusher and the puller to provide a first force, and an adjustable brake structured and arranged to provide an adjustable braking force to reduce the first force, wherein the pressure is slidably selected by adjusting the adjustable braking force applied to reduce the first force; and accordingly, when the syringe is seated on the base, the pusher slides the puller in a distal direction A force syringe pump assembly comprising: a cover that contacts the head of the plunger to apply a substantial force, said force is sufficient to move the plunger of the syringe and distribute liquid from the chamber at a desired flow rate; and a cover pivotably connected to the proximal end of the base, wherein a linkage is pivotably connected between the cover and the puller and is structured and arranged to convert the opening of the cover into movement toward the proximal end of the puller and the pusher, and when the syringe is positioned, the closing of the cover causes the pusher to engage with the plunger, moves the puller toward the distal end, and tensions the at least one spring to apply the force to the plunger of the syringe. Claim 28 A stimulating syringe pump assembly according to claim 27, wherein the adjustable brake is associated with the at least one spring, and the adjustable brake provides the adjustable braking force to the at least one spring. Claim 29 In paragraph 27, the adjustable brake is associated with the pusher, and the adjustable brake provides the adjustable braking force to the pusher, a strength syringe pump assembly. Claim 30 In paragraph 27, the adjustable braking force is selected by selecting a predefined setting for the adjustable brake, in a syringe pump assembly. Claim 31 In claim 27, the adjustable braking force is a user-modifiable syringe pump assembly to increase or decrease the force applied to the head of the plunger. Claim 32 A stamina syringe pump assembly according to claim 27, wherein the stamina provided by the adjustable actuator is a force of about 1 to 25 pounds. Claim 33 In claim 27, a stimulating syringe pump assembly, wherein the pump is structured and arranged to accommodate a syringe having a volume of at least 5 milliliters and 120 milliliters or less. Claim 34 A power syringe pump assembly according to claim 27, wherein the power pump has a flow rate indicator, and the braking force is selected by adjusting the adjustable brake to a desired flow rate indicated by the flow rate indicator. Claim 35 In claim 27, the adjustable braking force is selected by a sizer and a selector, which are at least partially provided by at least one controller associated with the adjustable braking force, and the selector is movable between a first position and a second position to set the size of the chamber, and the sliding movement of the selector from the first position to the second position allows the controller to adjust the adjustable braking force to adjust the braking force for the at least one spring, thereby providing a specific force for the size of the chamber, a force syringe pump assembly. Claim 36 A stimulating syringe pump assembly according to claim 27, wherein the cover is connected to the base by a unidirectional friction hinge, the unidirectional friction hinge provides a first resistance in a closed operation and a second resistance in an open operation, the second resistance being greater than the first resistance.

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