COMPOSITION TO REDUCE LIVER TRIGLYCERIDES AND / OR IMPROVE GLUCOSE METABOLISM
Patent Information
- Authority / Receiving Office
- MX · MX
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2022-10-25
- Publication Date
- 2026-06-12
AI Technical Summary
Type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD) are exacerbated by the accumulation of hepatic triglycerides and impaired glucose metabolism, primarily due to poor dietary and lifestyle habits, with existing treatments lacking effective means to address these issues.
Oral administration of yogurt containing branched-chain amino acid metabolites (h-BCAAs) generated during fermentation, which improve insulin sensitivity and reduce hepatic triglycerides and glucose metabolism by influencing the liver metabolome.
h-BCAAs, such as HIGA, HIVA, and HMVA, effectively lower fasting glucose, insulin levels, and hepatic triglycerides, thereby preventing or treating insulin resistance, T2D, and NAFLD by enhancing insulin's action on glucose metabolism in liver and muscle cells.