High affinity variants of SH2 domains
WO2024233798A3PCT designated stage expired Publication Date: 2025-01-09AXOIYA INC
Patent Information
- Application Number
- PCT/US2024/028614
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-05-09
- Filing Date
- 2024-05-09
- Publication Date
- 2025-01-09
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Figure US2024028614_09012025_PF_FP_ABST
Abstract
The present disclosure provides for high affinity variants of SH2 domains, methods of manufacturing such compositions, their use in screening, and in methods of their administration. The compositions and methods provided herein can be used for targeting protein phosphorylation of tyrosine residues as a means for identifying markers of pathology for therapeutic interventions.
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Citation Information
Patent Citations
SH2 domain variants
US20190271705A1
Cell-free protein expression systems and methods of use thereof
WO2007044894A2