Heart failure therapeutic main unit and heart failure therapeutic instrument

Abstract

Provided are a heart failure therapeutic main unit and a heart failure therapeutic instrument. The heart failure therapeutic main unit is configured to be assembled with and connected to a syringe, wherein the syringe comprises a barrel and a plunger rod, which is located in the barrel; and a tail end of the plunger rod is provided with at least one pull hook. The heart failure therapeutic main unit comprises: an end cover, which is configured to limit the syringe at an unlocking position and a locking position, the locking position being reached by the syringe rotating on the axis thereof from the unlocking position; a rotating head, which is configured to axially limit the barrel and which can be driven by the barrel to rotate; and a push-pull rod, which is configured to drive, along the axis, the plunger rod to advance and retreat, wherein an engagement slot is provided in a peripheral side of a front end of the push-pull rod; the push-pull rod is provided with at least one avoidance notch, which extends from a front end face so as to be in communication with the engagement slot; when the syringe is at the unlocking position, the at least one pull hook is located in the engagement slot and is opposite the at least one avoidance notch in a one-to-one correspondence manner; and when the syringe is at the locking position, the at least one pull hook is located in the engagement slot and is not opposite the at least one avoidance notch.

Description

Heart failure treatment host and heart failure treatment device

[0001] Cross-references

[0002] This application refers to Chinese Patent Application No. 202310721487.1 filed on June 16, 2023, entitled “Heart Failure Treatment Host and Heart Failure Treatment Device,” which is incorporated into this application in its entirety by reference. Technical Field

[0003] The present application relates to the technical field of medical equipment, and in particular to a heart failure treatment host and a heart failure treatment instrument. Background Art

[0004] Heart failure refers to a series of symptoms caused by insufficient blood perfusion due to dysfunction of the heart and its inability to completely drain blood from the heart. Heart failure is generally divided into acute heart failure and chronic heart failure.

[0005] Acute heart failure is the most common type of acute left ventricular failure, which refers to a clinical syndrome characterized by acute myocardial damage or increased cardiac load, resulting in a sudden drop in cardiac output, increased pulmonary circulation pressure, and increased peripheral circulation resistance, which in turn causes pulmonary circulation congestion and acute pulmonary congestion, pulmonary edema, and may be accompanied by insufficient perfusion of tissues and organs and cardiogenic shock.

[0006] Chronic heart failure is divided into right heart failure and left heart failure. In right heart failure, the right ventricle's ability to eject blood decreases, leaving more blood in the right heart, leading to increased right heart pressure and difficulty in blood flow. Because the blood flowing into the right heart is systemic, it causes systemic congestion. Because the lower limbs are located lower in the body, congestion is most severe in the lower limbs. When water enters the surrounding tissues from the blood vessels in the lower limbs, it causes lower limb edema. In left heart failure, because the blood flowing into the left heart is pulmonary, it causes increased left atrial pressure and pulmonary venous pressure, which in turn causes pulmonary congestion and pulmonary edema.

[0007] In some cases, depending on the severity of acute heart failure, the initial treatment is oxygen inhalation, and diuretics and cardiotonic drugs are given intravenously; if the condition still does not improve, vasoactive drugs are used to dilate and constrict blood vessels; if the condition is severe, blood pressure continues to drop or even cardiogenic shock occurs, it is necessary to monitor hemodynamics and adopt emergency non-drug treatment methods.

[0008] Treatment options in some situations have limitations. For example, some patients respond well to intravenous diuretics, while others do not. This is because when the body is overloaded with fluid, most of the excess fluid is not actually contained within the blood vessels, but rather in the spaces surrounding cells, a tissue called the interstitium. To fully decongest, excess fluid in the interstitial space must first be moved into the blood vessels. In healthy individuals, this is accomplished through the lymphatic system, which actively drains fluid into the large veins above the heart. However, in patients with acute heart failure, pressure within the large veins can be very high, slowing or even preventing the flow of lymph fluid into the veins, hindering the decongestion process. Studies have found that incomplete diuresis (i.e., fluid retention) is a strong predictor of hospital readmission and mortality. As many as half of acute heart failure patients are incompletely diureticized upon discharge, leading to approximately 25% of patients being readmitted within one month and approximately half of patients being readmitted within six months.

[0009] Intermittent balloon inflation to occlude the superior and inferior vena cava can effectively reduce cardiac pumping pressure and enhance the return of excess fluid from the interstitial tissue into the lymphatic system and into the blood vessels, thereby alleviating fluid retention and improving the patient's postoperative cure rate. In this approach, a heart failure treatment device and a disposable high-pressure injector are required to intermittently inflate and pressurize the balloon catheter and release fluid at set intervals, thereby achieving intermittent balloon occlusion of the superior and inferior vena cava, thereby alleviating cardiac pumping pressure and reducing fluid retention in heart failure.

[0010] How to improve the reliability of the connection between the heart failure treatment host and the syringe, thereby improving the effect of heart failure treatment, is a technical problem that needs to be solved urgently.

[0011] Summary of the Invention

[0012] The embodiments of the present disclosure provide a heart failure treatment host and a heart failure treatment device to improve the reliability of the connection between the heart failure treatment host and the syringe, thereby improving the effect of heart failure treatment.

[0013] According to one aspect of the present disclosure, a heart failure treatment host is provided for assembly and connection with a syringe, the syringe comprising a syringe and a piston rod located in the syringe, wherein the end of the piston rod has at least one hook, and the heart failure treatment host comprises: an end cover for limiting the syringe in an unlocked position and a locked position, wherein the locked position is reached by rotating the syringe around its axis from the unlocked position; a rotating head for limiting the axial position of the syringe and capable of being driven to rotate by the syringe; and a push-pull rod for driving the piston rod forward and backward along the axis, wherein a groove is provided on the front circumference of the push-pull rod, and the push-pull rod has at least one avoidance notch extending from its front end surface to communicate with the groove, wherein, when the syringe is in the unlocked position, the at least one hook is located in the groove and is one-to-one opposite to the at least one avoidance notch, and when the syringe is in the locked position, the at least one hook is located in the groove and avoids being opposite to the at least one avoidance notch.

[0014] In some embodiments, the slot is an annular slot.

[0015] In some embodiments, at least one hook is interference fit with the slot.

[0016] In some embodiments, the at least one hook is two hooks arranged opposite to each other, and the at least one avoidance gap is two avoidance gaps arranged opposite to each other.

[0017] In some embodiments, the locked position is reached by rotating the syringe 90° clockwise or 90° counterclockwise about its axis from the unlocked position.

[0018] In some embodiments, the syringe has a flange, and the periphery of the flange has a first positioning protrusion; the end cover has a first blocking portion, a second blocking portion and a first through hole for the syringe to pass through, wherein, when the syringe is in the unlocked position, the first positioning protrusion is adjacent to the first blocking portion, and when the syringe is in the locked position, the first positioning protrusion is adjacent to the second blocking portion.

[0019] In some embodiments, the end cover has a flange groove for positioning the flange, and the first blocking portion, the second blocking portion and the first through hole are provided in the flange groove.

[0020] In some embodiments, the heart failure treatment host also includes: a rotating head base, the rotating head is rotatably arranged on the rotating head base, wherein the end circumference of the syringe has two second positioning protrusions arranged opposite to each other, and the rotating head is provided with a second through hole for the syringe to pass through and two positioning grooves arranged in one-to-one correspondence with the two second positioning protrusions.

[0021] In some embodiments, the heart failure treatment host is configured to be connected to two syringes arranged side by side, wherein the two syringes rotate in the same direction from an unlocked position to a locked position.

[0022] According to another aspect of the present disclosure, a heart failure treatment device is provided, comprising: the heart failure treatment host of the aforementioned aspect; a syringe assembled and connected to the heart failure treatment host; and a catheter assembled and connected to the syringe.

[0023] According to one or more embodiments of the present disclosure, not only is it convenient to assemble and disassemble the syringe, but it can also improve the reliability of the connection between the heart failure treatment host and the syringe, thereby improving the effect of heart failure treatment.

[0024] These and other aspects of the disclosure will be apparent from and elucidated with reference to the embodiments described hereinafter. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following briefly introduces the drawings required for use in the embodiments of the present application. Obviously, the drawings described below are only some embodiments of the present application. For those skilled in the art, other drawings can be obtained based on the drawings without inventive work. In the following description of exemplary embodiments in conjunction with the drawings, more details, features and advantages of the present disclosure are disclosed. In the drawings:

[0026] FIG1 is a schematic diagram of a three-dimensional structure of a heart failure treatment host and a syringe assembled and connected in some embodiments of the present disclosure;

[0027] FIG2 is a front view schematic diagram of the structure of the heart failure treatment host and the syringe assembly connection according to some embodiments of the present disclosure;

[0028] FIG3 is a schematic diagram of the three-dimensional structure of a syringe in some embodiments of the present disclosure;

[0029] FIG4 is a schematic diagram of a partially disassembled structure of a heart failure treatment host and a syringe according to some embodiments of the present disclosure; and

[0030] FIG5 is a schematic diagram of the cross-sectional structure of a heart failure treatment host according to some embodiments of the present disclosure, taken along the AA direction in FIG1 .

[0031] Explanation of the accompanying reference numerals: 100-heart failure treatment host; 200-syringe; 21-syringe; 22-piston rod; 221-retractor; 211-flange; 212-first positioning protrusion; 213-second positioning protrusion; 13-end cover; 131-first blocking portion; 132-second blocking portion; 133-first through hole; 134-flange groove; 14-rotating head base; 15-rotating head; 151-second through hole; 152-positioning groove; 16-push-pull rod; 161-slot; 162-avoidance gap. DETAILED DESCRIPTION

[0032] Hereinafter, only certain exemplary embodiments are briefly described. As will be appreciated by those skilled in the art, the described embodiments may be modified in various ways without departing from the spirit or scope of the present disclosure. Therefore, the drawings and description are to be considered as illustrative in nature and not restrictive.

[0033] The heart failure treatment device requires a disposable high-pressure syringe to inflate and release the balloon. In related art, assembly and disassembly of the heart failure treatment device from the disposable high-pressure syringe often presents difficulties due to the rubber piston at the end of the piston rod within the disposable high-pressure syringe not rotating properly. Furthermore, this improper rotation of the rubber piston leads to poor contact with the push-pull rod, preventing it from being accurately driven by the push-pull rod. This weakens the balloon's filling and release effects, resulting in poor heart failure treatment results.

[0034] The embodiments of the present disclosure provide a heart failure treatment host and a heart failure treatment device to improve the reliability of the connection between the heart failure treatment host and the syringe, thereby improving the effect of heart failure treatment.

[0035] As shown in Figures 1, 2, and 3, some embodiments of the present disclosure provide a heart failure treatment host 100 for connection to a syringe 200. The syringe 200 includes a syringe 21 and a piston rod 22 located therein. The distal end of the piston rod 22 may be configured as a rubber piston having at least one retractor 221. As shown in Figures 4 and 5, the heart failure treatment host 100 includes an end cap 13, a rotating head 15, and a push-pull rod 16.

[0036] As shown in Figure 2 , the end cap 13 is used to position the syringe 200 between an unlocked position R and a locked position L, wherein the locked position L is reached by rotating the syringe 200 about its axis from the unlocked position R. The rotating head 15 is used to axially limit the syringe 21 and can be driven to rotate by the syringe 21. The push-pull rod 16 is used to drive the piston rod 22 forward and backward along the axis. As shown in Figure 4 , the push-pull rod 16 has a slot 161 on its front end and at least one relief notch 162 extending from its front end surface to communicate with the slot 161.

[0037] As shown in Figures 2 and 5, when the syringe 200 is in the unlocked position R, the at least one retractor 221 is located in the slot 161 and corresponds one-to-one with the at least one avoidance notch 162. At this time, there is no axial interference between the push-pull rod 16 and the piston rod 22, and the at least one retractor 221 can enter the slot 161 through the at least one avoidance notch 162. Figures 2 and 5 illustrate two syringes 200, respectively in the unlocked position R and the locked position L.

[0038] As shown in Figures 2 and 5, when the syringe 200 is in the locking position L, the at least one hook 221 is located in the slot 161 and avoids being opposite to the at least one avoidance notch 162. At this time, the push-pull rod 16 and the piston rod 22 interfere with each other in the axial direction, so that the push-pull rod 16 can drive the piston rod 22 forward and backward along the axis.

[0039] As shown in Figures 4 and 5, when the heart failure treatment host 100 of the embodiment of the present disclosure is assembled and connected with the syringe 200, the syringe 200 is set to the unlocking position R, at which time the push-pull rod 16 and the piston rod 22 are also unlocked from each other in the axial direction. The syringe 200 is rotated to the locking position L, at which time the push-pull rod 16 and the piston rod 22 are also locked to each other in the axial direction. Therefore, in the process of the push-pull rod 16 driving the piston rod 22 forward and backward, the push-pull rod 16 can be reliably locked with the piston rod 22, and the rubber piston at the end of the piston rod 22 can be accurately driven by the push-pull rod 16. The design of the heart failure treatment host 100 of the present disclosure is not only convenient for assembly and disassembly with the syringe 200, but also can improve the reliability of the connection between the heart failure treatment host 100 and the syringe 200, thereby improving the effect of heart failure treatment.

[0040] In the embodiment of the present disclosure, the side of the component that is closer to the needle of the syringe 200 (not shown in the figure) is defined as the "front", and the side of the component that is farther away from the needle of the syringe 200 (not shown in the figure) is defined as the "rear", and the directions are shown in the figure.

[0041] As shown in Figures 1 and 2 , in some embodiments, a heart failure treatment device 100 is configured to be assembled and connected to two syringes 200 arranged side by side, thereby enabling intermittent balloon inflation and occlusion of blood in the superior and inferior vena cava using one heart failure treatment device 100 and two syringes 200. In this design, the aforementioned structure for the syringes 200 is provided in two groups. For example, the heart failure treatment device 100 includes two rotating heads 15 and two push-pull rods 16.

[0042] As shown in FIG2 , in some embodiments, the locked position L is achieved by rotating the syringe 200 90 degrees (°) clockwise or counterclockwise about its axis from the unlocked position R. Selecting an appropriate rotation stroke can provide a certain feel for the operation and further improve the reliability of the locking between the push-pull rod 16 and the piston rod 22.

[0043] In some embodiments, the two syringes 200 rotate in the same direction from the unlocked position R to the locked position L. In this way, the installation operation method of the two syringes 200 is the same, which can further improve the convenience of assembly and facilitate the rapid disassembly and assembly of the syringes 200.

[0044] As shown in Figure 4, in the embodiment of the present disclosure, the front end peripheral side of the push-pull rod 16 has a groove 161, thereby forming a column head structure on the front side of the groove 161, and the at least one avoidance gap 162 extends from the front end surface of the push-pull rod 16 to communicate with the groove 161, that is, the at least one avoidance gap 162 can be formed on the column head structure.

[0045] In the embodiments of the present disclosure, there is no limit on the number of hooks 221 provided on the rubber piston at the end of the piston rod 22. Depending on the design size of the hook 221 in the circumferential direction, the strength of the hook 221, and the required connection strength between the piston rod 22 and the push-pull rod 16, the hook 221 can be designed to be one, two, or more. In some embodiments of the present disclosure, as shown in FIG3 , two hooks 221 are provided at the end of the piston rod 22, and the two hooks 221 are arranged opposite to each other in the circumferential direction. Correspondingly, two opposite avoidance notches 162 are provided at the front end of the push-pull rod 16. Such a design balances the radial force on the piston rod 22, making it easier for the rubber piston of the piston rod 22 to be accurately driven by the push-pull rod 16.

[0046] In some embodiments, the slot 161 is an annular slot. In other embodiments of the present disclosure, the slot 161 can also be designed as multiple sections distributed along the circumference according to the number and rotation stroke of the hooks 221 at the end of the piston rod 22, which is not specifically limited in the present disclosure.

[0047] In some embodiments of the present disclosure, at least one hook 221 on the rubber piston forms an interference fit with the slot 161. The hook 221 is made of rubber and forms an interference fit with the slot 161. This creates a certain amount of friction between the two. In the absence of external force or minimal, unintentional external force, relative rotation between the piston rod 22 and the push-pull rod 16 is unlikely, thereby improving assembly accuracy and connection reliability.

[0048] In the disclosed embodiment, the end cap 13 is used to limit the syringe 200 in the unlocked position R and the locked position L. As shown in Figures 2, 3, and 4, the syringe 21 has a flange 211, and the periphery of the flange 211 has a first positioning protrusion 212. The flange 211 is at a distance from the end of the syringe 21. The end cap 13 has a first blocking portion 131, a second blocking portion 132, and a first through hole 133 for the syringe 21 to pass through. When the syringe 200 is in the unlocked position R, the first positioning protrusion 212 is adjacent to the first blocking portion 131. When the syringe 200 is in the locked position L, the first positioning protrusion 212 is adjacent to the second blocking portion 132. The specific structural form of the first blocking portion 131 and the second blocking portion 132 is not limited, as long as they can have a blocking and stopping effect on the syringe 200 in the unlocked position R and the locked position L.

[0049] In some embodiments of the present disclosure, as shown in FIG2 , the end cap 13 has a flange groove 134 for positioning the flange 211. The first blocking portion 131, the second blocking portion 132, and the first through-hole 133 are disposed in the flange groove 134. Thus, the flange 211 can only rotate about its axis within the flange groove 134 by a certain angle without moving radially. This design facilitates improved assembly precision.

[0050] In the disclosed embodiment, as shown in Figures 4 and 5, the heart failure treatment host 100 further includes a rotating head base 14, on which a rotating head 15 is rotatably mounted. The distal end of the syringe 21 has two second positioning protrusions 213 disposed opposite each other. The rotating head 15 is provided with a second through hole 151 for the syringe 21 to pass through, and two positioning grooves 152 corresponding to the two second positioning protrusions 213. When the two second positioning protrusions 213 are positioned in the two positioning grooves 152 in a one-to-one correspondence, the rotating head 15 can rotate along with the syringe 21.

[0051] The structural design of the above embodiment is only for a part of the structure of the heart failure treatment host 100, and the present disclosure does not make any specific limitations on the structural design of other parts of the product.

[0052] The embodiment of the present disclosure also provides a heart failure treatment device, comprising a heart failure treatment host 100 according to any of the aforementioned embodiments, a syringe 200 assembled and connected to the heart failure treatment host 100, and a catheter assembled and connected to the syringe 200.

[0053] Since the heart failure treatment host 100 and the syringe 200 can be reliably connected, the treatment effect of the heart failure treatment device is improved. In addition, the disassembly and assembly operations of the heart failure treatment host 100 and the syringe 200 are also relatively convenient.

[0054] It should be understood that in this specification, the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships or dimensions based on the orientations or positional relationships or dimensions shown in the accompanying drawings, and these terms are used only for the convenience of description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the scope of protection of the present disclosure.

[0055] Furthermore, the terms "first," "second," "third," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of the technical features being referred to. Thus, a feature identified as "first," "second," or "third" may explicitly or implicitly include one or more of the features. Throughout the present disclosure, "plurality" means two or more, unless otherwise specifically defined.

[0056] In this disclosure, unless otherwise expressly specified or limited, terms such as "mounted," "connected," "connect," and "fixed" should be understood broadly. For example, they may refer to fixed connections, detachable connections, or integration; mechanical connections, electrical connections, or communication; direct connections or indirect connections through an intermediate medium; and internal connections between two components or interactions between two components. Those skilled in the art will understand the specific meanings of these terms in this disclosure based on specific circumstances.

[0057] In the present disclosure, unless otherwise expressly specified or limited, a first feature being "above" or "below" a second feature may include the first and second features being in direct contact, or may include the first and second features being in contact not directly but through another feature between them. Moreover, a first feature being "above," "above," and "above" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below," "below," and "below" a second feature includes the first feature being directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0058] This specification provides many different embodiments or examples that can be used to implement the present disclosure. It should be understood that these different embodiments or examples are purely exemplary and are not intended to limit the scope of protection of the present disclosure in any way. Those skilled in the art can conceive of various changes or replacements based on the disclosure of the specification of the present disclosure, all of which should be included within the scope of protection of the present disclosure. Therefore, the scope of protection of the present disclosure should be based on the scope of protection defined by the appended claims.

Claims

1. A heart failure treatment host, used for assembly and connection with a syringe, the syringe comprising a syringe and a piston rod located in the syringe, wherein: The end of the piston rod has at least one hook, and the heart failure treatment host comprises: an end cap for limiting the syringe in an unlocked position and a locked position, wherein the locked position is reached by the syringe rotating about its axis from the unlocked position; A rotating head, used to limit the axial position of the syringe and capable of being driven to rotate by the syringe; and A push-pull rod is used to drive the piston rod forward and backward along the axis, wherein the front end peripheral side of the push-pull rod has a groove, and the push-pull rod has at least one avoidance gap extending from its front end surface to communicate with the groove, wherein, when the syringe is located in the unlocking position, the at least one pull hook is located in the groove and corresponds to the at least one avoidance gap one by one, and when the syringe is located in the locking position, the at least one pull hook is located in the groove and avoids being opposite to the at least one avoidance gap.

2. The heart failure treatment host according to claim 1, wherein: The clamping groove is an annular clamping groove.

3. The heart failure treatment host according to claim 1 or 2, wherein: The at least one hook is interference fit with the slot.

4. The heart failure treatment host according to any one of claims 1 to 3, wherein: The at least one draw hook is two draw hooks arranged opposite to each other, and the at least one avoidance gap is two avoidance gaps arranged opposite to each other.

5. The heart failure treatment host according to any one of claims 1 to 4, wherein: The locked position is reached by rotating the syringe from the unlocked position about its axis by 90° clockwise or 90° counterclockwise.

6. The heart failure treatment host according to any one of claims 1 to 5, wherein: The syringe has a flange, and the periphery of the flange has a first positioning protrusion; The end cover has a first blocking portion, a second blocking portion and a first through hole for the syringe to pass through, wherein when the syringe is located in the unlocked position, the first positioning protrusion is adjacent to the first blocking portion, and when the syringe is located in the locked position, the first positioning protrusion is adjacent to the second blocking portion.

7. The heart failure treatment host according to claim 6, wherein: The end cover has a flange groove for positioning the flange, and the first blocking portion, the second blocking portion and the first through hole are arranged in the flange groove.

8. The heart failure treatment host according to any one of claims 1 to 7, further comprising: A rotating head base, wherein the rotating head is rotatably arranged on the rotating head base, wherein the end circumferential side of the syringe has two second positioning protrusions arranged opposite to each other, and the rotating head is provided with a second through hole for the syringe to pass through and two positioning grooves arranged in a one-to-one correspondence with the two second positioning protrusions.

9. The heart failure treatment host according to any one of claims 1 to 8, wherein: The heart failure treatment host is used for being assembled and connected with the two syringes arranged side by side, wherein the two syringes rotate in the same direction from the unlocking position to the locking position.

10. A heart failure treatment device, wherein: include: A heart failure treatment host according to any one of claims 1 to 9; A syringe connected to the heart failure treatment host assembly; as well as Connect the catheter to the syringe assembly.

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