Device and method for releasing gas from solid-liquid reaction

Abstract

A device for releasing gas from a solid-liquid reaction, the device comprising a solid material container (101), a liquid material container (102) and a conduit (103), wherein the solid material container (101) contains a solid material (1); a sealing cap (2) is provided above the solid material (1); the liquid material container (102) is located above the solid material container (101) and contains a liquid material (3); a sealing cap (4) is provided above the liquid material (3); the sealing cap (4) and a liquid-material container bottom (7) are respectively provided with positioning guide holes (5, 6, 8) for the insertion of the conduit (103); the conduit (103) comprises a gas conduit (9), a liquid conduit (12), and a limiting cap (10); a gas filter layer (11) is provided on an upper portion of the interior of the gas conduit (9), and holes are provided in a wall of a middle-lower portion of the liquid conduit (12) for guiding the flow of a liquid; and a liquid-flow limiting layer (14) is provided in an annular gap between outer and inner pipes below the holes (13).

Description

Device and method for releasing gas by solid-liquid reaction Technical Field

[0001] The present invention relates to a device and method for releasing gas through solid-liquid reaction, which are used to generate gases such as nitric oxide and carbon dioxide, and particularly to the fields of corresponding gas preparation and medical treatment. Background Art

[0002] Nitric oxide (NO) is a colorless gas that is slightly soluble in water. Research has found that its fat-soluble nature allows it to act as a messenger molecule in the human body. Nitric oxide molecules can easily cross cell membranes, causing the smooth muscle cells surrounding blood vessels to relax and dilate, thus aiding the treatment of cardiovascular and pulmonary diseases and providing health benefits.

[0003] Currently, nitric oxide stored in cylinders must be diluted to a certain concentration before use in medical procedures. Strict concentration requirements apply, and the process requires strict monitoring. Inhalation exceeding certain concentrations and quantities can be harmful to the body. Therefore, it is generally only suitable for centralized use in medical institutions and is not suitable for portable or home use. Furthermore, due to its active chemical properties, nitric oxide easily undergoes disproportionation reactions, converting it to nitrogen dioxide and nitrous oxide, making it unsuitable for long-term storage. To reduce costs and facilitate individual and home use, a number of manufacturers, both domestically and internationally, have developed portable nitric oxide generators. These portable nitric oxide generators fall into two main categories based on their generation principle: one utilizes gas discharge technology, as described in Chinese Patent Publication (CN113456966A), and the other utilizes electrolysis of solutions such as nitrite, as described in Chinese Patent Publication (CN111636071A). However, these nitric oxide generators are active devices, requiring high technical requirements for operation and maintenance, and therefore have yet to gain widespread adoption. Technical issues

[0004] The inventors of the present invention have disclosed a method for reacting solid ferric chloride with nitric oxide gas in a gas stream to obtain a nitric oxide-containing product, ferrous nitrosyl chloride (Fe(NO)Cl3) (Chinese Patent 201610541447.9). Based on the nitroso-containing product obtained by the above method, the present invention has developed a portable solid-liquid reaction gas release device and method for producing gases such as nitric oxide and carbon dioxide to meet related needs. Technical Solutions

[0005] A device for releasing gas by solid-liquid reaction, characterized in that the device comprises a solid material container 101, a liquid material container 102 and a conduit 103. The solid material container 101 contains solid material 1, which has a sealing cover 2 on top of the solid material. The solid material container is topped by a liquid material container 102, which contains liquid material 3, which has a sealing cover 4 on top of the liquid material. Positioning guide holes (5, 6 and 8) are respectively provided on the sealing cover 2, the sealing cover 4 and the bottom 7 of the liquid material container. The conduit 103 comprises a gas conduit 9 (inner tube), a liquid conduit 12 (outer tube) and a limiting cover 10. The gas conduit 9 and the liquid conduit 12 are fixed to the limiting cover. Tube 9 passes through the stopper cap. A gas filter layer 11 is located at the upper portion of the gas conduit to remove water mist and other harmful gases. The top of the liquid conduit 12 is fixed to the stopper cap. A small hole 13 is opened in the lower wall of the liquid conduit 12 to guide the liquid. A liquid flow-restricting layer 14 is located in the annular gap between the outer and inner tubes below the small hole to control the dripping rate of the liquid. The stopper cap 10 and the positioning guide hole 5 can be sealed by a bayonet or threaded connection. In addition to securing the gas-liquid conduit, the stopper cap 10 also serves to limit the insertion depth of the gas conduit. The upper end of the solid material container and the lower end of the liquid material container can be sealed by threaded connection.

[0006] The method of using the device for releasing gas by solid-liquid reaction is to first connect the solid material container and the liquid material container, then insert the conduit from the upper part of the liquid material container through the positioning guide hole, pass through each sealing cover, and connect the liquid container to the solid container space through the opening on the liquid conduit. The gas conduit is also connected to the solid container space. When the opening 13 on the outer wall of the liquid conduit is lower than the liquid level of the liquid agent in the liquid container, the liquid material in the liquid material container will pass through the hole and the liquid flow-restricting layer 14 into the solid material container, contact and mix with the solid material, and a chemical reaction will occur. The gas generated during the reaction is discharged from the gas conduit through the filter layer to remove water mist and acidic gas that may be generated by the solid-liquid reaction for use.

[0007] The function of the liquid flow restriction layer is to control the liquid's downward flow velocity. This can be achieved by filling it with a resistance layer such as filter cotton or filter cloth. For example, absorbent cotton, non-woven fabric, or glass wool can be used, followed by compaction and compaction. Hydrophilic materials are preferred. A composite resistance layer containing a solid powder layer can also be used. Microporous filter materials such as quartz glass, ceramic, or plastic can also be used as the resistance layer, with comparable effectiveness. The resistance layer height can generally range from 10 to 30 mm, but the specific height can be determined based on needs and after testing.

[0008] The amount of liquid entering the solid material container can also be adjusted by adjusting the insertion depth of the gas conduit, thereby regulating the progress of the solid-liquid reaction. A limit cap on the conduit limits the maximum insertion depth of the gas conduit and seals it with the positioning guide hole in the sealing cap above the liquid material through a bayonet or threaded connection. The liquid conduit and the positioning guide hole fit tightly together to prevent liquid leakage.

[0009] The solid and liquid storage containers can be of various shapes, generally cylindrical, and can be filled with inert gas such as nitrogen for protection. The size, position and number of the holes on the wall of the liquid conduit can be determined according to actual use requirements.

[0010] The device of the present invention can be applied to chemical unit operations such as gas generation, solid dissolution and chemical synthesis related to solid-liquid reactions, such as the reaction of sodium carbonate solution with solid ferric chloride and nitrosyl ferric chloride:

[0011] 3Na2CO3+ 2FeCl3+ 3H2O → 2Fe(OH)3+ 6NaCl + 3CO2↑ (1)

[0012] 3Na2CO3+ 2Fe(NO)Cl3+ 3H2O → 2Fe(OH)3+ 6NaCl + 3CO2↑+ 2NO↑ (2)

[0013] For example, if solid carbonate reacts with dilute hydrochloric acid or dilute sulfuric acid:

[0014] CaCO 3 + 2HCl → CaCl2+ H2O + CO2↑ (3) Beneficial effects

[0015] Compared with the existing technology, the advantage of the present invention is that the solid medicine and the liquid medicine are encapsulated in different containers, and a catheter is inserted from the top of the container to mix the liquid medicine and the solid medicine to produce a chemical reaction. The obtained gas is discharged through the gas catheter, and the liquid descent speed can be adjusted by adjusting the insertion depth of the catheter, thereby controlling the progress of the solid-liquid reaction. It has the characteristics of simple operation, easy to carry, available at any time, safe and efficient. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figures 1 to 3 are schematic diagrams of a solid-liquid reaction gas release device, wherein Figure 1 is a combination of a solid material container and a liquid material container; Figure 2 is a conduit; and Figure 3 is the complete device after the combination.

[0017] In the figure: 101 solid material container; 102 liquid material container; 103 conduit; 1 solid material; 2 sealing cover; 3 liquid material; 4 sealing cover; 5, 6, 8 positioning guide holes; 7 bottom of liquid material container; 9 gas conduit; 10 limiting cover; 11 gas filter layer; 12 liquid conduit; 13 hole; 14 liquid flow limiting layer. Best Mode for Carrying Out the Invention

[0018] The best embodiment of the present invention is described in Example 1. Modes for Carrying Out the Invention

[0019] The present invention is further described in detail below with reference to the accompanying drawings and examples.

[0020] Figures 1-3 illustrate a solid-liquid reaction gas release device. The device comprises a solid material container 101, a liquid material container 102, and a conduit 103. The solid material container 101 contains solid material 1, which is capped with a sealing cap 2. The solid material container is capped with a liquid material container 102, which contains liquid material 3, which is capped with a sealing cap 4. Seal caps 2, 4, and the bottom 7 of the liquid material container are each provided with positioning holes (numbered 5, 6, and 8) to facilitate insertion and positioning of the conduit. The upper end of the solid material container and the lower end of the liquid material container are sealed by threaded butt joints. The conduit 103 comprises a gas conduit 9 (inner tube), a liquid conduit 12 (outer tube) and a limiting cover 10. The gas conduit 9 and the liquid conduit 12 are fixed to the limiting cover, wherein the gas conduit 9 passes through the limiting cover 10, and a gas filter layer 11 is provided in the upper inner part of the conduit; the top of the liquid conduit 12 is fixed to the limiting cover, and a small hole 13 is opened on the middle and lower wall of the conduit for guiding liquid into the liquid conduit. A liquid flow limiting layer 14 is provided in the annular gap between the outer tube and the inner tube below the small hole for controlling the dripping speed of the liquid.

[0021] The steps for using the device are to first assemble the solid material container and the liquid material container as shown in Figure 1. Then, a conduit is inserted downward from the top of the liquid medicine container through the positioning guide hole, passing through each sealing layer (cover) and the guide hole. The liquid medicine in the liquid material container flows through the opening on the outer wall of the liquid conduit and the liquid flow-restricting layer into the solid medicine container. The gas generated during the solid-liquid reaction is discharged from the gas conduit through the gas filter layer 11 to remove water mist for use.

[0022] Example 1: A device for releasing nitric oxide gas through a solid-liquid reaction is shown in Figures 1-3. Both the container and conduit are made of PP plastic. The liquid container has a diameter of approximately 44 mm and a total height of approximately 90 mm. The lower solid dosage container has a diameter of approximately 46 mm and a height of approximately 120 mm. The conduit dimensions are as follows: the liquid conduit measures approximately 10 mm x 150 mm. A pair of symmetrical holes with a diameter of 5 mm are located approximately 70 mm from the bottom of the conduit. A liquid flow restriction layer (annular gap) is located approximately 15 mm below the holes. The flow restriction layer is filled with a compacted hydrophilic non-woven fabric layer to a height of approximately 30 mm. The gas conduit measures approximately 7 mm x 250 mm (the upper portion of the restriction cap is approximately 100 mm). A gas filter layer made of absorbent cotton is located within the conduit and is approximately 30 mm high.

[0023] The solid medicine filling amount is about 40 grams, the active ingredient nitrosoferric chloride content is about 1%, water content is about 10%, residual ferric chloride, and the liquid material is sodium carbonate solution (concentration is about 10%), which is about 80 ml. After the gas conduit is fully inserted, the liquid material enters the solid container. The solid-liquid reaction time is about 10 minutes, and the maximum concentration of nitric oxide at the outer port of the gas conduit is about 200 ppm.

[0024] Example 2: The solid agent is about 20 grams of calcium carbonate, the liquid agent is about 120 milliliters of a dilute hydrochloric acid solution with a concentration of about 5%, and other conditions are the same as in Example 1. The total carbon dioxide release time is about 8 minutes.

[0025] Example 3: The filling heights of the liquid flow-restricting layer in the liquid conduit are 15 mm and 20 mm, respectively. Other conditions are the same as in Example 1. The solid-liquid reaction times are approximately 4 min and 6 min, respectively. Industrial Applicability

[0026] The present invention relates to a portable solid-liquid reaction gas releasing device and method, which are used to generate gases such as nitric oxide and carbon dioxide. Sequence Listing Free Content

[0027] (none).

Claims

1. A device for releasing gas by solid-liquid reaction, characterized in that The device is composed of a solid material container, a liquid material container and a conduit, wherein the solid material container contains solid material, a sealing cover is provided on the upper part of the solid material, the upper part of the solid material container is a liquid material container, the liquid material container contains liquid material, a sealing cover is provided on the upper part of the liquid material, the sealing cover and the bottom of the liquid material container are respectively provided with positioning guide holes for the conduit to be inserted, the conduit includes a gas conduit (inner tube), a liquid conduit (outer tube) and a limiting cover, a gas filter layer is provided in the upper part of the gas conduit, a hole is opened on the middle and lower wall of the liquid conduit for guiding the liquid, and a liquid flow limiting layer is provided in the annular gap between the outer tube and the inner tube below the hole.

2. The device for releasing gas by solid-liquid reaction according to claim 1, characterized in that The upper end of the solid material container and the lower end of the liquid material container are butt-jointed and sealed via threads.

3. The device for releasing gas by solid-liquid reaction according to claim 1, characterized in that A limit cover is arranged on the upper part of the catheter to limit the maximum insertion depth of the catheter.

4. The device for releasing gas by solid-liquid reaction according to claim 1, characterized in that The liquid flow-limiting layer is filled with absorbent cotton, non-woven fabric or glass wool or a composite layer containing a solid powder layer, or is filled with a quartz glass, ceramic or plastic filter element layer.

5. The device for releasing gas by solid-liquid reaction according to claim 1, characterized in that The method of using the device for releasing gas by solid-liquid reaction is to first dock the solid material container and the liquid material container, then insert the conduit from the upper part of the liquid material container through the positioning guide hole, and after passing through each sealing cover, the liquid container is connected with the solid container space through the opening on the liquid conduit, and the gas conduit is also connected with the solid container space. When the opening on the outer wall of the liquid conduit is lower than the liquid level of the liquid agent in the liquid container, the liquid material in the liquid material container enters the solid material container through the hole through the liquid flow limiting layer, contacts and mixes with the solid material to produce a chemical reaction, and the gas generated in the reaction process is removed from the gas conduit through the filter layer to remove the water mist and acidic gas that may be produced by the solid-liquid reaction, and then is discharged for use.

6. The device for releasing gas by solid-liquid reaction according to claim 1 or 5, characterized in that The device is applied to gas generation, solid dissolution and chemical synthesis processes related to solid-liquid reactions.

7. The device for releasing gas by solid-liquid reaction according to claim 1 or 5, characterized in that The device is applied to the process of generating nitric oxide gas by the reaction of sodium carbonate solution and ferric nitrosyl chloride.

8. The device for releasing gas by solid-liquid reaction according to claim 1 or 5, characterized in that The device is applied to the process of generating carbon dioxide gas by the reaction of sodium carbonate solution with dilute hydrochloric acid or dilute sulfuric acid.

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