Vapor exposure model experimental device

By designing a smoke exposure model experimental device containing a cylindrical exposure groove, air intake mechanism and camera, the problem of complex operation of existing devices and inability to monitor the fine behavior of mice is solved, real-time observation and tracking of the experimental subject's behavior is achieved, and a good experimental basis is provided.

WO2025065844A1PCT designated stage expired Publication Date: 2025-04-03SHENZHEN INST OF ADVANCED TECH
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Patent Information

Application Number
PCT/CN2023/133605
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-09-28
Filing Date
2023-11-23
Publication Date
2025-04-03

AI Technical Summary

Technical Problem

The existing smoke exposure experimental detection device is complex in operation and cannot effectively monitor the fine behavioral characteristics of mice.

Method used

A smoke exposure model experimental device is designed, including a cylindrical exposure groove, an air intake mechanism and a camera, which provides the same smoke exposure conditions through the air intake mechanism, and uses the camera to observe the behavior of the experiment in real time.

Benefits of technology

It realizes real-time online observation and tracking of the behavior of the experimental subject, which is convenient to operate and can better monitor the fine behavior characteristics of the experimental subject, providing a good foundation for subsequent model establishment and quantitative analysis.

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Abstract

A vapor exposure model experimental device, comprising: an exposure chamber (1), which is divided into a plurality of vapor compartments (101); an air intake mechanism (2), which is fixed in the exposure chamber, and which is provided with a plurality of air inlets (203) and a plurality of air outlets (204), each air inlet (203) being in communication with one corresponding vapor compartment (101), and each air outlet (204) being in communication with one corresponding vapor compartment (101); a vapor generator (3), which is in communication with the air inlets (203) of the air intake mechanism (2); and a camera (4), which is arranged above the exposure chamber (1) and used for observing the exposure chamber (1). The vapor exposure model experimental device enables vapor exposure experiments to be conducted by means of the exposure chamber (1) and the vapor generator (3), and the air intake mechanism (2) provides the same exposure condition for the vapor compartments (101), facilitating synchronous vapor experiments on different experimental subjects; thus, the device involves an easy operation while enabling online real-time observation of experimental subject behavior.
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Description

A smoke exposure model experimental device Technical Field

[0001] The invention belongs to the technical field of experimental devices, and in particular relates to a smoke exposure model experimental device. Background Art

[0002] The rise in the use of electronic nicotine delivery systems (ENDS), or e-cigarettes, is believed to increase the risk of addiction, particularly among adolescents. Understanding and assessing the behavior of ENDS-related addictive mouse models is fundamental to studying the neuropsychiatric effects of e-cigarettes. However, little is known about the behavioral characteristics of mice during e-cigarette exposure. Current assessments of addictive behavior rely on nicotine withdrawal-induced anxiety, which can only be assessed after ENDS exposure. Traditional behavioral assays, such as reward-based place preference and anxiety-based behavior after smoke withdrawal, include open field tests and elevated cross tests. The corresponding smoke test apparatus is shown in Figures 13-15. These behavioral assays are complex, time-consuming, and labor-intensive. They are also inconvenient for tracking mouse trajectories and cannot effectively monitor detailed behavioral characteristics of mice.

[0003] Based on this, the present application provides a smoke exposure model experimental device, which is equipped with an air intake mechanism in the exposure slot, and can simultaneously conduct smoke exposure experiments under the same conditions in different smoke chambers, making it convenient to track the behavior trajectory of the experimental subject, and at the same time, the fine behavior of the experimental subject can be observed through the camera.

[0004] Summary of the Invention

[0005] The purpose of the present invention is to provide a smoke exposure model experimental device to solve the shortcomings of the smoke exposure experimental detection device in the prior art, which is complicated to operate and cannot well observe the fine behavior of mice.

[0006] A smoke exposure model experimental device, comprising:

[0007] exposure trough, partitioned into multiple smoke chambers;

[0008] The air intake mechanism fixed in the exposure groove is provided with a plurality of air inlets and a plurality of air outlets; each air inlet is connected to a corresponding smoke chamber, and each air outlet is connected to a corresponding smoke chamber;

[0009] a smoke generator connected to the air inlet of the air intake mechanism;

[0010] The camera is arranged above the exposure slot and is used to observe the exposure slot.

[0011] In the present invention, the exposure groove is cylindrical, the air intake mechanism is located in the middle of the exposure groove, and each smoke chamber has the same size and shape. By arranging in this way, each smoke chamber obtains the same conditions for smoke exposure.

[0012] Furthermore, the cross section of the smoke chamber is a regular shape, including but not limited to a sector shape and a square shape.

[0013] Preferably, the cross section of the smoke chamber is fan-shaped, so that the key points of the exposed slot are the center point and the edge position with the largest radius, which facilitates the identification and tracking of the key points of the smoke and the tracking of the activity trajectory of the experimental subject according to the position radius.

[0014] Furthermore, the number of the smoke chambers is four or eight, and correspondingly, the number of the air inlets and the air outlets of the air intake mechanism is four or eight.

[0015] In the present invention, the air intake mechanism includes a main body and an air nozzle; the main body is cylindrical, with a partition layer inside to form two cavities, and a smoke exhaust hole is provided at the bottom of the main body; the air inlet is evenly distributed on the top of the main body, and the air outlet is evenly distributed on the bottom of the main body; the air nozzle is fixedly connected to the top of the main body, and the air nozzle is provided with a smoke inlet hole.

[0016] The present invention further comprises a pump, which is connected to the air nozzle of the air intake mechanism through a pipe.

[0017] In the present invention, the smoke generator is arranged on the pipe connecting the pump and the air intake mechanism, so that the smoke generator is connected to the smoke inlet hole of the air intake mechanism through the pipe and is also connected to the pump through the pipe.

[0018] Furthermore, the smoke generator includes an electronic cigarette, a fixing member and a shell; the electronic cigarette is arranged in the shell and connected to the fixing member.

[0019] The present invention further includes a control mechanism, which is electrically connected to the pump and the smoke generator. The control mechanism is used to turn the pump on and off, and to pause the operation of the smoke generator.

[0020] Furthermore, the control mechanism is provided with an infrared sensing module, a WiFi wireless module and a Bluetooth module, and communicates with the mobile terminal or remote control via the infrared sensing module, the WiFi wireless module and the Bluetooth module.

[0021] The present invention further comprises a main control machine, wherein the main control machine is electrically connected to the camera head, and the main control machine is also electrically connected to the control mechanism.

[0022] The present invention has the following beneficial effects:

[0023] (1) The smoke exposure model experimental device of the present invention conducts smoke exposure experiments through an exposure tank and a smoke generating device. The air intake mechanism provides the same exposure conditions to the smoke chamber, which facilitates simultaneous smoke experiments on different experimental subjects. The operation is convenient and the behavior of the experimental subjects can be observed online in real time.

[0024] (2) The cylindrical exposure slot and air intake mechanism of the device of the present invention, combined with the fan-shaped cross-section of the smoke chamber, facilitate the tracking of the experimental subject's behavioral trajectory, providing a good foundation for subsequent model establishment and quantitative analysis. This device can be used to screen for pleasant aerosol substances or smoking cessation drugs. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The technical solution of the present invention will be further described below with reference to the accompanying drawings and embodiments.

[0026] FIG1 is a schematic diagram of the overall structure of the smoke exposure model experimental device of the present invention;

[0027] Figures 2-4 are schematic diagrams of the orientation structure of the exposure slot and the camera of the present invention;

[0028] FIG5 is a schematic diagram of the internal structure of the exposure groove of the present invention;

[0029] FIG6 is a schematic diagram of the overall structure of the air intake mechanism of the present invention;

[0030] FIG7 is a front view of the air intake mechanism of the present invention;

[0031] FIG8 is a rear view of the air intake mechanism of the present invention;

[0032] FIG9 is a top view of the air intake mechanism of the present invention;

[0033] FIG10 is a bottom view of the air intake mechanism of the present invention;

[0034] FIG11 is a cross-sectional view of the air intake mechanism of the present invention;

[0035] FIG12 is a schematic structural diagram of a smoke generator of the present invention;

[0036] Figures 13-15 are smoke test devices in the prior art;

[0037] The reference numerals in the figure are as follows: 1. exposure slot; 2. air intake mechanism; 3. smoke generator; 4. camera; 5. control mechanism; 6. main control unit; 7. pump; 8. pipe; 101. smoke chamber; 102. partition; 201. main body; 202. air nozzle; 203. air inlet; 204. air outlet; 205. smoke inlet hole; 206. smoke exhaust hole; 207. partition; 301. electronic cigarette; 302. fixing part; 303. shell. DETAILED DESCRIPTION

[0038] The smoke exposure model experimental device shown in Figure 1-12 includes an exposure tank 1, an air intake mechanism 2, a smoke generator 3 and a camera 4.

[0039] The exposure tank 1 is cylindrical and is divided into eight smoke chambers 101 of equal size and shape by partitions 102. The cross-section of each smoke chamber 101 is fan-shaped. An air intake mechanism 2 is fixedly connected to the middle of the exposure tank 1. The air intake mechanism 2 includes a main body 201 and an air nozzle 202, which is fixedly connected to the top of the main body 201. The main body 201 is cylindrical and has a partition 207 inside, which divides the interior of the main body 201 into two cavities. The main body 201 has eight air inlets 203 evenly distributed on the top and eight air outlets 204 evenly distributed on the bottom. There is also a smoke exhaust hole 206, which is connected to each air outlet 204 through a cavity. Each air outlet 204 is connected to a smoke chamber 101. The air nozzle 202 has a smoke inlet hole 205, which is connected to each air inlet 203 through another cavity. Each air inlet 203 is connected to a smoke chamber 101. Four cameras 4 are provided above the exposure tank 1 , and the cameras 4 are used to record the behavioral changes of the experimental subjects under different smoke exposure conditions.

[0040] The smoke generator 3 includes an electronic cigarette 301, a fixing member 302, and a housing 303. The electronic cigarette 301 is disposed within the housing 303 and fixedly connected to the fixing member 302. The smoke generator 3 is connected to the smoke inlet 205 of the air nozzle 202 of the air intake mechanism 2 via a tube 8, and is also connected to the pump 7 via the tube 8. After the smoke generator 3 generates the electronic cigarette 301 smoke, under the action of the pump 7, the smoke flows along the tube 8 to the air intake mechanism 2, then passes through the air nozzle 202 of the air intake mechanism 2 through the air inlet 203 and enters different smoke chambers 101, where it is dispersed. Finally, the smoke in different smoke chambers 101 is discharged through the bottom air outlet 204 and the smoke exhaust hole 206. Since the air intake mechanism 2 is located in the middle of the exposure slot 1, the smoke conditions provided in each smoke chamber 101 are the same.

[0041] The present invention further includes a control mechanism 5. The control mechanism 5 is electrically connected to the pump 7 and is used to control the on and off of the pump 7, thereby facilitating the regulation of experimental conditions such as the amount of smoke and the smoke exposure time. The pump 7 can be a local structure within the control mechanism 5, or it can be connected to the control mechanism 5 as an independent unit. In this embodiment, the pump 7 is electrically connected to the control mechanism 5 as an independent unit. The control mechanism 5 is also electrically connected to the smoke generator 3 and is used to control the suspension of the operation of the smoke generator 3 and adjust the amount of smoke generated. The control mechanism 5, the pump 7, and the smoke generator 3 work together to provide different smoke exposure conditions for the smoke chamber 101 in the exposure tank 1, providing conditions for observing and collecting the behavioral characteristics of the experimental subjects under different smoke conditions.

[0042] The control mechanism 5 also has an infrared sensing module, a WiFi wireless module and a Bluetooth module, which communicate with the mobile terminal or remote control through the infrared sensing module, WiFi wireless module and Bluetooth module. In this way, relevant operations of the pump 7 and the smoke generator 3 can be performed through the mobile terminal or remote control, thereby improving the convenience of use.

[0043] The device of the present invention also includes a main control unit 6, which is electrically connected to the camera 4. The main control unit 6 transmits the real-time behavior of the subject recorded by the camera 4 to the main control unit 6 for data processing, construction of a model, and correlation of the behavior with indicator results. Based on these indicator results, the behavioral characteristics of the subject and the activity status within a specific time period are analyzed, thereby determining the impact of different fumes on the subject's behavior. The smoke exposure model experimental device of the present invention can be used to screen for pleasant aerosol substances or smoking cessation drugs through smoke experiments.

[0044] The above disclosure is merely a preferred embodiment of the present invention and certainly cannot be used to limit the scope of the present invention. Therefore, equivalent changes made according to the claims of the present invention are still within the scope of the present invention.

Claims

1. A smoke exposure model experimental device, characterized in that: include: The exposure groove (1) is divided into a plurality of smoke chambers (101); An air intake mechanism (2) fixed in the exposure groove (1) is provided with a plurality of air intake ports (203) and a plurality of air outlet ports (204); each air intake port (203) is in communication with a corresponding smoke chamber (101), and each air outlet port (204) is in communication with a corresponding smoke chamber (101); A smoke generator (3) is connected to the air inlet (203) of the air inlet mechanism (2); A camera (4) is arranged above the exposure groove (1) and is used to observe the exposure groove (1).

2. The smoke exposure model experimental device according to claim 1, characterized in that: The exposure groove (1) is cylindrical, the air intake mechanism (2) is located in the middle of the exposure groove (1), and each smoke chamber (101) has the same size and shape.

3. The smoke exposure model experimental device according to claim 2, characterized in that: The cross section of the smoke chamber (101) is a regular shape, including but not limited to a sector shape and a square shape.

4. The smoke exposure model experimental device according to claim 3, characterized in that: The air intake mechanism (2) comprises a main body (201) and an air nozzle (202); the main body (201) is cylindrical, and has a partition (207) therein to form two cavities, and a smoke exhaust hole (206) is provided at the bottom of the main body (201); the air intake ports (203) are evenly distributed at the top of the main body (201), and the air outlet ports (204) are evenly distributed at the bottom of the main body (201); the air nozzle (202) is fixedly connected to the top of the main body (201), and the air nozzle (202) is provided with a smoke intake hole (205).

5. The smoke exposure model experimental device according to claim 4, characterized in that: It also comprises a pump (7), wherein the pump (7) is connected to the air nozzle (202) of the air intake mechanism (2) via a pipe (8).

6. The smoke exposure model experimental device according to claim 5, characterized in that: The smoke generator (3) is arranged on a pipe (8) connecting the pump (7) and the air intake mechanism (2), so that the smoke generator (3) is connected to the smoke inlet hole (205) of the air intake mechanism (2) through the pipe (8) and is also connected to the pump (7) through the pipe (8).

7. The smoke exposure model experimental device according to any one of claims 1 to 6, characterized in that: The smoke generator (3) comprises an electronic cigarette (301), a fixing member (302) and a housing (303); the electronic cigarette (301) is arranged in the housing (303) and connected to the fixing member (302).

8. The smoke exposure model experimental device according to claim 6, characterized in that: It also comprises a control mechanism (5), wherein the control mechanism (5) is electrically connected to the pump (7); the control mechanism (5) is also electrically connected to the smoke generator (3).

9. The smoke exposure model experimental device according to claim 8, characterized in that: The control mechanism (5) is provided with an infrared sensing module, a WiFi wireless module and a Bluetooth module, and communicates with a mobile terminal or a remote controller via the infrared sensing module, the WiFi wireless module and the Bluetooth module.

10. The smoke exposure model experimental device according to claim 9, characterized in that: It also includes a main control machine (6), the main control machine (6) is electrically connected to the camera (4), and the main control machine (6) is also electrically connected to the control mechanism (5).

Citation Information

Patent Citations

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  • Uniform administration type exposure tower

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