Installation for extracting bioactive sanogenic substances from plant or animal

The modular extraction system addresses inefficiencies in existing technologies by using a combination of solvent flow, ultrasonic field, and thermal control to efficiently extract bioactive sanogenic substances from plant or animal cells, achieving high yield and minimal energy consumption.

WO2025116760A1PCT designated stage expired Publication Date: 2025-06-05TATAR DANIEL
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Patent Information

Application Number
PCT/RO2024/050009
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-11-27
Filing Date
2024-11-07
Publication Date
2025-06-05

AI Technical Summary

Technical Problem

Existing technologies for extracting bioactive sanogenic substances from plant or animal cells are inefficient, often requiring high temperatures that destroy heat-sensitive compounds, and are not suitable for extracting multiple active principles from complex preparations without repeated operator intervention.

Method used

The installation uses a modular extraction system with fluid circulation tubes and solenoid valves, a pump, and ultrasonic transducers attached to a metal wall, allowing for simultaneous action of solvent flow, ultrasonic field, and thermal field to extract bioactive substances without exceeding recommended extraction temperatures.

Benefits of technology

This approach enables high-yield extraction of bioactive substances with minimal energy consumption, allowing for the production of therapeutic extracts with enhanced concentration and diversity, while maintaining the integrity of heat-sensitive compounds.

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Abstract

The present invention relates to an installation for extracting bioactive sanogenic substances from plant or animal cells, which are vital in the metabolism, health and lifespan of the human body, by means of ultrasound and to a specific process using the same. The installation uses ultrasound to extract bioactive substances from plant or animal cells through a controlled process involving an extraction module, a filtering capsule, ultrasonic transducers, and a system of vessels and filters that enables the circulation and heating of the solvent, thereby optimizing the exploitation of active substances.
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Description

[0001] Installation for extracting bioactive sanogenic substances from plant or animal cells by means of ultrasound

[0002] The present invention relates to an installation for extracting bioactive sanogenic substances from plant or animal cells, which are vital in the metabolism, health and lifespan of the human body, by means of ultrasound and to a specific process using the same.

[0003] Such an installation can also be used for the preparation of beverages and other extracts such as teas or coffees, but it is especially important for the undegraded production of compounds containing sanogenic bioactive substances, such as antioxidants and enzymes, obtained in particular from plants (teas) in a proportion at least twice as high as that of ordinary teas and preparations, which substances are extremely important for the optimal metabolism of cells in the human body. They also ensure a body cell replication number that exceeds the average of 125 times in a lifetime, which means prolonging it.

[0004] Also, the part of biological regeneration without DNA damage, i.e. youth and maturity, can be considerably increased compared to the current average by such substances.

[0005] The value and importance of these extracts are based on universally accepted scientific knowledge, including the fact that any biochemical and physiological function at the cellular level is impossible without the presence of enzymes, which act as catalysts in the metabolism and amplify the speed of intracellular chemical reactions by thousands of times. It should also be noted that above 40 degrees Celsius, all enzymes are irreparably destroyed.

[0006] At the same time, this intracellular metabolism inevitably creates free radicals, and if said metabolism is not working properly, free radicals increase in number and diversity and wreak havoc primarily on the immune system. It is well known that free radicals are responsible for over 100 diseases, 90% of cancers and 80% of the progressive degradation of proteins called telomeres that protect the integrity of DNA during cell replication, which is similar to the onset of old age and the depletion of the human body's vitality.

[0007] Substances that annihilate the activity of free radicals, thus contributing to health, the immune system and proper regeneration of the body, including the restoration of telomeres - through the action of the enzyme telomerase - are antioxidants. However, it should be noted that most of them are also heat-sensitive, i.e. they are progressively destroyed as the temperature rises above 40 degrees Celsius. Moreover, antioxidants are found only in plant tissues and not in any animal body! Suddenly we are discovering the immense value of plant extracts, with all their variety, starting with common teas. An edifying table of the presence of antioxidants in the plant world that can provide valuable clues to sources of health and long life or even exceptionally valuable food bases in terms of taste, flavor and nutrition is published in the ORAC (OXYGEN RADICAL ABSORBANCE CAPACITY) scale.

[0008] A main objective of the invention is that of the correct and optimized exploitation of these plants, in the aforementioned sense.

[0009] In order to extract several types of active principles from the same preparation, repeated procedures are routinely required, using different solvents, different temperatures, a certain order and certain well determined processing time periods.

[0010] There are preparations, most often herbal preparations, whose composition comes from empirical tradition and practice, which can be made from mixtures of substances of very diverse origin, such as organic products of plant origin (flowers, seeds, leaves, roots, etc.), of animal origin (bone powders, dried and crushed insect powders), extracts of various animal components (eggs, organs, etc.), as well as of mineral origin (clays, mineral powders, zeolites, etc.) or various chemical compounds.

[0011] Due to the diversity of the composition of the preparations, a multitude of different operations are required for the extraction of the active principles. Thus, various heating, dissolving, recirculation and filtration operations are required, using a variety of solvents, certain operating temperatures, a certain order and certain well determined time periods, so that one particular operation does not compromise the subsequent ones to which the preparation is subjected. It is clear that the procedure called decoction, i.e., prolonged boiling, can destroy the active and boiling-sensitive principles extracted by infusion, and those extracted by infusion can destroy the ones sensitive to temperatures above 40 degrees Celsius extracted by maceration at room temperature.

[0012] Known in the prior art is document EP2079348 disclosing an embodiment of a machine for brewing tea.

[0013] This machine features a perforated basket containing the tea leaves, which is magnetically attached to a conveyor and moved up and down in a heated water tank. The basket is lowered into the water when the water temperature is found to have reached a preset value suitable for brewing tea and is then raised when the brewing is complete. The down and up movements of the basket are achieved using a hydraulic system. This is the most advanced tea maker on the world market. Its disadvantages are many, starting with the fact that it can only be used for one type of extraction, from one type of tea leaves, at one temperature, with one quantity of solvent, being totally unsuitable for the multitude of elements of interest in these leaves, or extractions from raw materials with complex compositions, such as heat-sensitive active principles, or bulkier compositions, such as mixtures of plant roots, or heavier compositions, such as mineral powders or zeolites.

[0014] Moreover, this machine does not allow the extraction of several different active principles from the same material without repeated operator intervention, nor the separate storage of the resulting extracts, each at different temperatures.

[0015] Also known in the prior art is document US9604755 disclosing an embodiment of an installation for extracting oils from plants.

[0016] This installation has the disadvantage that it is intended to be used on an industrial scale, only for oil extraction, and has a complex operating mode and requires cooling and heating systems for each of the component parts in order to be operated.

[0017] Also known in the prior art is patent US 1029939A, which is a percolator. The disadvantages are the same as in the aforementioned examples, with the remark that here high temperatures are used in particular, at which the influence of thermal agitation in the solvent compromises thermally degradable extracts.

[0018] Also known are documents DE 202008016797U1 and US 352 516A, where the previous disadvantages are also present with the additional remark that here capsules floating in the solvent are used, without their position favoring rapid diffusion of the extract.

[0019] Also known are industrial installations of ultrasonic processors, such as Hielscher UP50H, or Ultrasonic CQ20 Processor, or VCX 130PB, or Cole-Palmer 500, etc., which use ultrasound in addition to high temperatures, based on the principle of cavitation.

[0020] These installations are massive, expensive and use a sonic transducer, the end of which is usually a stainless steel or titanium rod that is immersed in the solvent in the center of the vessel containing the preparation, which is more or less evenly dispersed in the liquid. The disadvantage of these installations is their bulkiness, i.e., the difficulty of processing preparations of small mass or volume, the high cost of manufacture and operation, and the disproportionate ratio between the small surface area of ultrasound emission in the solvent and the large volume in which the preparation is dispersed. The extraction is based on the high ultrasonic vibration power induced in the immersed titanium rod. The installations also have the disadvantage that they are not very mobile, and the distances in solvent from the ultrasound source to the preparation undergoing extraction are relatively large compared to the size of the ultrasound emitting pivot, which leads to massive energy consumption, and implicitly to the danger of overheating the solvent, which destroys the heat-sensitive components in the case of macerates, which are of particular interest to us. Here there is an obvious complexity of the ultrasonic power source and long times of inefficient operating, as well as an obvious lack of other combined methods to increase the extraction and dispersion in solvent of the extract from the preparation compared to the ultrasonic wave source.

[0021] All the given examples use a single solvent, a single temperature which is usually high and destroys the most valuable principles, and the complex extractions requiring different thermal values of extraction for each compound of interest are not properly exploited in this respect.

[0022] The main objective of the invention is to produce an installation intended for both commercial and personal use, and therefore being mobile, cheap, fast and easy to handle, for obtaining therapeutic bioactive sanogenic extracts, containing bioactive substances in the form of infusion, decoction, macerate, digest, filtrate, tincture or the like, characterized by high efficiency, and therefore with high yield and low energy consumption.

[0023] It is preferable that the bioactive sanogenic extracts are separated by extraction phases in different vessels and ready for use, at the desired volume and temperature. The extraction processes must not alter the bioactive sanogenic substances, must be synergistically conjugated, effective, with the shortest extraction time and a high yield, by means of multiple extraction phases in correct sequence and with the possibility of varying the volume, temperature and type of solvent. This allows a much higher yield and diversity than in the conventional extraction method, especially evident in the maceration phase, which is particularly important for health and longevity.

[0024] A further objective of the present invention is that the achieved installation can operate automatically, be programmable and wherein all the necessary operations, more numerous and varied, can be carried out in minimum time and using a minimum number of vessels, connections between them, of machinery and closing and opening elements of the operation of all parts of the installation, without human intervention or supervision, so that the intervention of human personnel is only necessary before the start of the extraction, by programming and supplying with the preparation and / or liquids / solvents for extraction. A further objective of the present invention is that the achieved installation allows anyone to extract on a large scale, in concentrations more than 2 times higher, the heat-sensitive bioactive sanogenic substances, compared to the current use of maceration below 40 degrees Celsius, and moreover, under conditions of advanced sterilization, which is obviously lacking in the simple processes applied on a large scale.

[0025] The resulting extract may contain one or more bioactive sanogenic substances: enzymes, vitamins, antioxidants, pigments, minerals, flavorings, bitter principles, tannins, volatile oils, essential oils, fats, vegetable mucilage, alkaloids, glycosides, saponins, colloidal substances, etc., with a significant therapeutic effect.

[0026] In order to achieve these objectives, the installation also has to solve some new technical problems, such as:

[0027] - obtaining ready-to-consume macerates without the need for ultraviolet sterilization, etc., which is usually neglected or done superficially, especially in domestic use, since the storage and handling of the preparations favors the appearance of dangerous microorganisms that are permanently growing, such as escherichia coli, listeria, salmonella, Campylobacter, norovirus, Clostridium perfringens, etc.

[0028] - the significant reduction in the complexity of ultrasound generators and their excessive consumption of electricity in the aforementioned case, which entails high costs and has the additional disadvantage of bulkiness and the fact that the intensity of the ultrasonic front created in the solvent by the titanium pivots causes the additional technical problem of a significant dissipation of heat energy from the contact of the metal of the pivots with the solvent. These dissipations cause an increase in the solvent temperature, which, in the case of extraction of heat-sensitive active principles, leads to irreversible damage of the same.

[0029] - the technical problem of automatically changing and sequencing a series of solvents for the same preparation with a minimum of circuit elements and by the simplest possible operations.

[0030] - substantial increase of the ultrasonic wavefront emission surfaces in contact with the solvent, which, for example in professional laboratory extractors and industrial installations of ultrasonic processors mentioned above, are reduced to the surface of the titanium rods immersed in the center of the solvent vessels, thus a minimum value for the large volume of solvent in question, knowing that ultrasound loses its energy with increasing propagation distances! The technical problem solved by the claimed installation consists in providing a technical means for increasing the speed of extraction of bioactive sanogenic substances from preparations / biological parts containing them, in the case of using ultrasonic wavefronts of relatively low intensity, in order not to compromise the integrity of the composition of the active sanogenic parts of these preparations, but with high efficiency, therefore with high yield and the lowest possible energy consumption.

[0031] The installation according to the invention solves this technical problem in that it has an extraction module for extracting bioactive sanogenic substances from an extraction preparation for the purpose of optimized exploitation thereof, comprising, joined by circuit elements such as fluid circulation tubes and solenoid valves, a pump which may be from the basic extraction technology or another in-house pump, all controlled manually or by an in-house automated program or associated with the basic extraction technology, some inlets and outlets for the liquid forming a solvent for the extraction preparation, which are connected to the inside of a main extraction vessel, all these components being connected to a distributor and to two or more adjacent vessels containing one or more adjacent solvents, which may be identical to or different from the solvent in the main extraction vessel in terms of composition, mass and adjacent temperatures, wherein the extraction of the bioactive sanogenic substances (of the active principles) from the extraction preparation is carried out by means of the action of ultrasound and by means of the solvent taken from the main vessel and / or from an adjacent vessel, with the aid of a distributor, by successive operations of emptying the solvent containing the extracted bioactive substances and refilling the respective extraction vessel with identical or similar solvent, wherein a flow F of solvent incorporating the bioactive sanogenic substances extracted from the extraction preparation is circulated through removable filters and / or through a filtering bag of a filtering capsule located in maximum proximity to at least one surface of a flat metal wall, said surface being in contact with both the solvent and the extraction preparation, the other surface of said metal wall being in contact with one or more flat ultrasonic transducers emitting ultrasonic fronts.

[0032] The filtering capsule, according to the invention, consists of a body of parallelepipedal or cylindrical shape or a combination of the two, wherein at the ends of the larger size of the body there is a removable wall of flat or curved shape or a combination of the two, which may each have one or more outlet openings, to which, as required, tubes for the circulation of the liquid / liquids acting as solvent are connected, wherein the removable walls may each be doubled, as required, by a removable filter inwards towards the body, which may also contain one or more side and / or top closing walls which are also fixed and / or removable and of suitable shapes in order to achieve partial or total closing of the body of the filtering capsule.

[0033] The metal wall next to the side closing walls has at least one flat portion, preferably with a surface in which at least one circle with a diameter preferably greater than 70 mm can be inscribed, and the extraction preparation is stored in the inner space of the filtering capsule between the removable filters, in maximum proximity to the metal wall.

[0034] The ultrasonic transducers have electrically insulated power supply wires, wherein their insulation is resistant to a wide range of liquids such as basic or acid solutions or alcohols, fats, etc. and temperatures above 100 degrees Celsius, and wherein the filtering bag can be closed and opened in order to contain the extraction preparation, its surface being in contact with the flow F of a solvent which flows through the inside of the filtering capsule body and contains dissolved and / or suspended bioactive sanogenic substances extracted by ultrasonication from the extraction preparation. The heating and temperature control of the solvent flow F can be done by a thermostatically controlled heater in an automated way.

[0035] The process for extracting bioactive sanogenic substances from plant or animal cells by means of ultrasound from an extraction preparation, according to the invention, is characterized in that the extraction preparation is subjected to the simultaneous action of at least one suitable solvent flow F, a suitable ultrasonic field and a thermal field, with automatic control of the solvent temperature so that in the action range of the ultrasonic field the temperature thereof is close to the recommended extraction temperature but without exceeding this value, the heating of the solvent flow F being carried out by means of a thermostatically controlled heater, and the ultrasonic field being achieved with ultrasonic transducers attached with the flat surface to a metal wall in contact with the solvent flow F and with a filtering bag containing the extraction preparation, which is distributed adjacent to the entire surface of the metal wall and in maximum proximity thereto, for maximum extraction efficiency of the bioactive sanogenic substances.

[0036] The installation, according to the invention, for extracting bioactive sanogenic substances from plant or animal cells by means of ultrasound, and the process, according to the invention, have the following advantages: - allowing the production of tea extracts from mixtures of two or more types of plants, each with their recommended extraction temperature (which can vary from 60 to 95 °C) and which can be stored in different containers or tanks, or, as required, in the same container or tank;

[0037] - allowing the production of different variants of cocktails, mixtures of fruit juices, coffee extract obtained from combinations of cold ground coffee beans, combined with coffee extract obtained by infusion in a solvent at various temperatures up to boiling point, and even different liquid food bases with a high level of concentration and nutritional value, in a period of time reduced several times compared to current processes;

[0038] - the solvent can be exchanged once or several times with other quantities and / or compositions in one or more other phases, so that the basic extraction technology is repeated in each of them with time and temperature parameters which may be identical and / or different, using for this purpose a module-type installation which is attached to the initial one, in order to extract active principles in larger and / or more diversified quantities from the same extraction preparation in order to optimize the exploitation of the same, comprising, in addition to the group of circuit elements such as fluid circulation tubes and solenoid valves, a pump which may be from the basic extraction technology or another in-house pump, all of which are controlled manually or by an in-house automated program or associated with the basic extraction technology;

[0039] - the extraction of the bioactive sanogenic substances from the extraction preparation may be continued in one or more additional steps or phases, wherein all these additional phases, as well as that of the basic technology, are separated by means of the distributor and the adjacent vessels by successive operations of emptying and refilling of the extraction vessel with adjacent solvents, which will each finally be found in the adjacent vessels together with parts and elements of the bioactive substances extracted under conditions specific to each additional phase;

[0040] - the extraction preparation, subjected to the simultaneous and synergistic action over certain periods of time, continuously or in successive intervals, of both a flow of solvent circulating in a certain quantity and at a certain temperature and ultrasonic action, releases - by means of the ultrasonic cavitation phenomenon - the sanogenic bioactive substances contained in the cells, with high efficiency, therefore with high yield and relatively low energy consumption, compared with the installations using a bar-type transmitter for the transmission of ultrasound to the liquid used as solvent, as a result of the use as ultrasound transmitter towards the extraction preparation and towards the solvent washing it, of at least one metal wall having at least one flat portion preferably with a surface in which at least one circle with a diameter preferably greater than 70 mm can be inscribed.

[0041] The installation according to the invention further has the following advantages:

[0042] - it is simple, easy to make and cheap to produce;

[0043] - the operation of the installation is carried out without the user coming into contact with the solvent;

[0044] - the installation exhibits increased reliability and extended service life;

[0045] - the installation allows the extraction of several different active principles from the same preparation in successive phases with solvents that may or may not be different in terms of composition or volume, and in several temperature increments, usually in ascending order;

[0046] - the installation allows the use of vessels both for the storage of solvents and for the storage of extracts and / or mixtures of extracts;

[0047] - the installation may be used for the automatic and successive performance of several types of operations such as maceration, digestion, infusion, boiling, tincturation, dissolution or filtration, etc.;

[0048] - the installation is suitable for home use as well as for specialized laboratories;

[0049] - the installation can be programmed as well as remotely controlled;

[0050] - the installation allows to obtain extracts much more valuable in terms of presence and concentration of bioactive substances compared to the simple presence of solvent, with or without the effect of temperature, wherein these extracted sanogenic substances maintain their properties in the extract to a greater extent, without degrading;

[0051] - the absence of human personnel during the technological extraction process, as they are not required for handling utilities or for supervision or control, as the technological flow is fully automated;

[0052] - the stages of the technological extraction process are carried out without time interruptions or unnecessary waiting times for the handling of the necessary equipment and can take place in stages that can be succeeded as desired, in different vessels with their solvents by simply moving the extraction module from one vessel to another;

[0053] - the number of vessels used in the installation is minimal, most of them having multiple functions, and the processing equipment ensures minimal human operator intervention; - heating, ultrasonication, fluid circulation control processes are performed with minimal energy consumption due to the possibility of lowering the extraction temperatures and with a minimum number of active devices;

[0054] - after programming and feeding, the installation can be automatically activated or deactivated and can ensure for a long time the preservation of extracts with active principles, ready to be used;

[0055] - synergistic association between a moving solvent flow at a certain temperature and in contact with a preparation undergoing extraction of active principles which is at the same time in maximum proximity to an ultrasound source, which performs cavitation and sterilization, and which is represented by a metal wall to which the respective ultrasound source is attached, together with various filters which perform filtration;

[0056] - the ultrasound is transmitted to the preparation simultaneously by successive flows of moving solvents, and the solvents may be only one or more, similar or different, and each having its own vessel, with the extract separate or combined with the others, and each having identical or different concentrations and stabilized temperatures.

[0057] The invention is disclosed in greater detail below with further reference to Figures 1 -3, which represent:

[0058] - fig. 1 is a schematic view in vertical section of a filtering capsule containing extraction material, according to an embodiment thereof;

[0059] - fig. 2 is a schematic illustration of an extraction module with its component parts, shown in relation to a vessel containing the extraction solvent;

[0060] - fig. 3 is a schematic illustration of a module-type installation, which is attached to the extraction module shown in Figure 2,

[0061] According to the invention, a component of the claimed installation for extracting active principles (sanogenic substances) from an extraction preparation is the filtering capsule shown in Figure 1 .

[0062] Figure 1 is a view in vertical section of the schematic of a filtering capsule containing the extraction material, according to a non-limiting embodiment of the present invention.

[0063] Figure 2 is a schematic and non-limiting illustration of an extraction module with its component parts, shown in relation to a vessel containing the solvent of an extraction stage, characterized by the solvent temperature and the corresponding time, as well as the time programmed for the emission of ultrasound at the appropriate intensity level, according to a non-limiting process and embodiment of the present invention. Figure 3 is a schematic illustration of a module-type installation, which is attached to the extraction module shown in Figure 2, but also to any existing installation containing a solvent vessel, for the case where extraction takes place in one or more additional phases, of which four are exemplarily shown in the drawing, where the solvent and the conditions of temperature, quantity, time and ultrasound emission differ, and the extracts obtained are stored by means of a distributor in the same vessels from which the solvents of the respective stage have been prepared, according to a non-limiting process and embodiment of the present invention, in which the four extraction phases are described.

[0064] For the extraction of sanogenic bioactive substances (active principles) PA from an extraction preparation PE which may in particular be a plant preparation (tea leaves), as shown in Figure 3, a basic extraction installation is used, as shown in Figure 2, comprising among other things a component in the form of a main extraction vessel V containing a solvent S at a temperature T, wherein the solvent S may be exchanged once or several times with other quantities and / or compositions in one or more other phases, so that the basic extraction technology is repeated with time and temperature T parameters which may be identical or different, using for this purpose an extraction module M of the installation, in order to extract the bioactive sanogenic substances PA in larger and / or more diversified quantities from the same extraction preparation PE in order to optimize the exploitation of the same.

[0065] The installation further comprises, according to the non-limiting example in Figure 3, in addition to a group of circuit elements such as fluid circulation tubes and solenoid valves, a pump P which may be from the basic extraction technology or another in-house pump P1 , all controlled manually or by an in-house automated program or associated with the basic extraction technology, wherein the extraction module M has some inlets IN and outlets IE connected directly or by means of other elements of the extraction installation with the inside of the main extraction vessel V thereof, all these components being connected to a distributor D and to 2-4 adjacent vessels V1, V2, V3 and V4 containing one or more adjacent solvents S1, S2 and S3, which may be identical to or different from the solvent S in the main extraction vessel V in terms of composition, mass and adjacent temperatures (T1 ,T2 and T3), wherein the extraction of the bioactive sanogenic substances (of the active principles) PA from the extraction preparation PE of the basic technology is continued in one or more additional steps or phases, each with the adjacent times (t, t1 , t2 and t3) of this non-limiting example, wherein all these additional phases, as well as that of the basic technology, are separated by means of a distributor D and of the adjacent vessels V1, V2, V3 and V4 by successive operations of emptying and refilling the main extraction vessel V with adjacent solvents S1, S2 and S3 which will each finally be found in the adjacent vessels V1, V2, V3 and V4, each together with parts and elements of the active principles PA extracted under conditions specific to each additional phase in particular.

[0066] The process can be applied anywhere there is an installation for obtaining teas or coffees or any extraction preparations PE of which we are interested in applying the maceration technique, and that of infusion or decoction, or even exchanging solvents without replacing the respective extraction preparation.

[0067] In this case, the phases are usually ordered in the direction of increasing temperatures, starting from the lowest.

[0068] The installation shown in Figures 1 -3, allows the implementation of a process for extracting bioactive sanogenic substances (active principles, PA) from an extraction preparation PE subject to the simultaneous and synergistic action, over certain continuous periods of time At or in successive steps, of a flow F of solvent S circulating in a certain quantity and at a certain temperature T, wherein this flow F of solvent washes the surface of the extraction preparation PE, and some removable filters 1.4 and / or 3, which are in maximum proximity to at least one surface of a flat metal wall 1 , which in turn is in contact both with the solvent S and possibly with the extraction preparation PE, and, through the other face thereof, with one or more ultrasonic transducers TU emitting ultrasonic fronts, which, in this simultaneous combination of circumstances, generates a synergistic effect in addition to the other extraction conditions, which causes the passage from the extraction preparation PE into the mass of solvent S of certain bioactive sanogenic substances containing active principles PA, which can be unaltered thermally, in a shorter time and at a higher concentration compared to other processes using similar temperatures, in dissolved and / or precipitated form and ready sterilized. This process, applicable with the installation according to the invention, comprises most of the solutions for solving the technical problems extracted by observation and analysis of the existing state of the art in the field, including filtration, which may be partial or total, as well as starting points for other technical problems resulting from the application of these solutions, as will be seen.

[0069] The filtering capsule CF of the installation, exemplified without limitation in Figure 1 , consists of a body C of approximately parallelepipedal or cylindrical shape or a combination of the two, wherein at the ends of the larger size of the body C there is a removable wall 1.1 of flat or curved shape or a combination of the two, which may each have one or more outlet openings 1.2 to which, as required, liquid circulation tubes may be connected, and the removable walls 1.1 may, as required, each be doubled inwards towards the body C by a removable filter 1.4, and the body C of the filtering capsule CF may also contain one or more side and / or top closing walls 1.3 which are also fixed and / or removable and of suitable shapes in order to achieve partial or total closing of the body C of the filtering capsule CF, which is further characterized in that:

[0070] - between the side closing walls 1.3 there is at least one metal wall 1 with a shape containing at least one flat section preferably with a surface in which at least one circle with a diameter preferably greater than 70 mm can be inscribed;

[0071] - between the removable filters 1.4 there is an interior space of the filtering capsule CF in which the extraction preparation PE can be stored in maximum proximity to the metal wall 1 ;

[0072] - on the flat inner or outer surface of the metal wall 1 , the outer or inner surface of the body C, the flat surface of one or more flat surfaces of one or more ultrasonic transducers TU is in direct contact with the electrically insulated power wires 2 and with their insulation which is resistant to a wide range of liquids such as basic or acid solutions or alcohols, fats, etc., and to temperatures above 100 degrees Celsius;

[0073] - inside the filtering capsule CF may be placed a removable filtering bag 3 made of metal or other material, which may have only a supporting function and / or a coarse or even fine filtering function, fixed in direct contact with - or in maximum proximity to - the metal wall 1 and / or the body of an ultrasonic transducer TU, wherein the filtering bag 3 may provide only support and / or coarse or even fine filtration, and may be closed and opened in order to contain the extraction preparation PE and, functionally, its surface is in contact with a flow F of a solvent S passing through the interior of the body C and containing the active principles PA in dissolved and / or suspended form.

[0074] It is noted that the filtering capsule CF assembly represents a sub-installation which embodies a way of implementing the claimed process. It is the origin of new technical problems which will in turn generate solutions, as will be seen.

[0075] The extraction module ME, shown in a non-limiting example in Figure 2, is characterized in that:

[0076] - it comprises a liquid circulation pump P, a thermostatically controlled heater 5 and a filtering capsule CF connected to each other in series, directly or by means of intermediate circulation tubes 6, which are preferably made of temperature-resistant silicone material and which may have internal diameters between 6 and 25 mm, in such a way that a solvent S can circulate through this chain of components and the free ends of this chain can communicate by means of the heater tube 6.1 and the capsule tube 6.2, respectively, with the volume of a solvent S contained inside a main extraction vessel V;

[0077] - it comprises an automation panel TA which contains the 20-40 KHz ultrasound generator 4 connected by power wires 2 to the ultrasonic transducer TU, and also contains elements which provide power supply, control of circuit elements such as the pump P, the heater 5, various solenoid valves, thermostat, etc., and can be programmed by means of WI-FI and / or Bluetooth and programs the start and stop times of the circulation of liquids as well as their temperatures and also the operating times and emitting powers of the ultrasound generator, wherein it also has a set of buttons and displays and signaling means for manual programming of all these sequences of operations;

[0078] - if its dimensions allow it, the extraction module ME can operate with the thermostatically controlled heater 5 and the filtering capsule CF partially or totally immersed in the solvent S, in which case the heater tube 6.1 and capsule tube 6.2 may be omitted.

[0079] This aspect is a technical solution to the problem related to the relative complexity of the installation, related to the fact that the invention aims to be applicable to portable dimensional measurements, compacted into small volumes.

[0080] The same considerations are behind the possibility of sometimes replacing the circulation pump P with a controlled-flow agitator, not shown in the drawings, whereby the flow is directed towards the extraction preparation PE.

[0081] The same considerations lead to a variant of an extraction module ME in which the reduced volume of solvent S in the main extraction vessel V can condense it dimensionally until matching with the extraction capsule CE. This aspect is mentioned in claim 7.

[0082] The same considerations of dimensioning the installation create the technical problem of the presence of the extraction capsule CE inside a main extraction vessel V in such a way that, in certain forms of construction and operation, the extraction module ME can be removed from the main extraction vessel V with the solvent S and can be reintroduced in connection with other vessels and other solvents, by various means. Thus, in claim 9, according to the invention, the immersible filtering capsule is defined, which is not shown in the drawings, and which is characterized in that, it is made in a simplified form, in which the metal wall 1 extends and encloses the ultrasonic transducers TU in an airtight inner space, the only connection to the outside being the power wires 2, thus forming a support body on which the filtering bag 3 containing the extraction preparation PE is fixed at the maximum proximity distance, and from a functional point of view, the immersible filtering capsule is partially or totally placed in the flow F of the solvent S.

[0083] The description of the extraction capsule CE also includes the solution to another new technical problem arising from the implementation of the new technical solutions of the patent. Due to the need to ensure maximum proximity between the metal wall 1 and the extraction preparation PE and / or the filtering bag 3, which belongs to the present patent, the heat released by this proximity between the ultrasonic transducers TU and the extraction preparation PE can sometimes exceed 40 degrees Celsius, which can compromise the quality of some active principles PA.

[0084] The new solution generated in this case by the new problems arising, is the one which provides, according to the invention, that in contact with the metal wall 1 of the filtering capsule CF, or in contact with the solvent S anywhere it is on the path along which it circulates, including in or on the surface of the main extraction vessel V, there may be a passive cooler, i.e. provided with cooling fins, or an active cooler, i.e. further provided with a cooling medium, which cooler is not shown in the drawing, and which has the function of extracting from the solvent S or from the body C of the filtering capsule the excess temperature produced by the activity of the ultrasonic transducers TU.

[0085] The process for extracting bioactive sanogenic substances from plant or animal cells by means of ultrasound from an extraction preparation PE, according to the invention, is thus carried out by subjecting the same to the simultaneous action of at least one suitable solvent flow F, of a suitable ultrasonic field and a thermal field, with automatic control of the solvent temperature so that in the range of action of the ultrasonic field its temperature is close to the recommended extraction temperature but without exceeding this value, wherein the solvent flow F is heated by a thermostatically controlled heater 5, and the ultrasonic field is produced by means of ultrasonic transducers TU attached with their flat surface to a metal wall 1 in contact with the solvent flow F, and a filtering bag 3 containing the extraction preparation PE distributed adjacent to the entire surface of the metal wall 1 and in maximum proximity thereto, for maximum extraction efficiency of the bioactive sanogenic substances. The process according to the invention aims at exploiting the advantages of both previously described processes, corresponding to Figures 1 , 2 and 3, resulting in the total exploitation, in all forms and components, of the optimal extraction of the active principles PA from a single complex extraction preparation PE. According to the process, the cumulative action of temperatures (t, t1 , t2, and t3) applied in successively increasing phases of their value and the separate storage of the active principles PA, i.e. of the sanogenic bioactive substances thus obtained, with the successive use in each phase of the same complex extraction process, in the presence of ultrasound applied at maximum proximity distance and with the flow F of solvent S, with simultaneous sterilization.

[0086] More specifically, the process according to the invention is characterized in that:

[0087] - it involves a technology whereby a flow F of solvent S circulating in a certain quantity and at a certain temperature T acts upon an extraction preparation PE which is subjected to the simultaneous and synergistic action over certain continuous periods of time t or in successive steps, which flow F incorporates the surface of an extraction preparation PE and several associated removable filters 1.4 and / or 3, wherein the extraction preparation PE is in maximum proximity to at least one surface of a flat metal wall 1 , which in turn is in contact both with the solvent S and possibly with the extraction preparation PE - directly or indirectly (through a filtering bag 3)- and, through one and / or the other one of its faces, with one or more ultrasonic transducers TU emitting ultrasonic fronts, which, in this simultaneous combination of circumstances, generates a synergistic effect in addition to the other extraction conditions, which causes the passage from the extraction preparation PE into the mass of solvent S of certain substances containing active principles PA, which can be unaltered thermally, in a shorter time and at a higher concentration compared to other processes using similar temperatures, in dissolved and / or precipitated form and ready sterilized, and also uses associated with this basic technology a second one, together with which it acts synergistically, comprising a module-type M installation attached to the initial one, for extracting active principles in larger and / or more diversified quantities from the same extraction preparation PE for the purpose of optimized exploitation thereof, which, according to the non-limiting example of Figure 3, in addition to the group of circuit elements such as fluid circulation tubes and solenoid valves, comprises a pump P of the basic extraction technology, or another inhouse pump P1 , all controlled manually or by an automated in-house program or associated with the basic extraction technology, and the module M, whose inputs IN and outputs IE are directly or by means of other elements of the basic extraction technology linked to it, is in connection with the interior of its extraction vessel V, and all these components are connected together with a distributor D and, without limitation, with two or more adjacent vessels V1, V2, V3 and V4 containing one or more adjacent solvents S1, S2 and S3, which may be identical to or different from the solvent S in the main extraction vessel V in terms of composition, mass and adjacent temperatures (T1 , T2 and T3), and the extraction of the active principles PA from the extraction preparation PE of the basic technology is continued in one or more additional steps or phases, each with the adjacent times (t, t1 , t2 and t3) of this non-limiting example according to the invention, and all these additional phases, as well as that of the basic technology with respect to them, (involving only the solvent S) are separated by means of the distributor D and of the adjacent vessels V1, V2, V3 and V4 by successive operations of emptying and refilling the extraction vessel V with the adjacent solvents S1, S2 and S3, which will each be finally found in the adjacent vessels V1, V2, V3 and V4, each together with parts and elements of the active principles PA extracted under conditions specific to each additional phase.

[0088] Examples of operation of the installation according to the process according to the invention a) An example of operation of the appended installation of Figure 3 of the invention, which is an embodiment of the process according to the invention as previously described, is disclosed.

[0089] Figure 3 shows a group of four adjacent vessels V1, V2, V3 and V4, the contents of which are represented respectively by adjacent solvents S, S1, S2 and S3 which may be identical to or different from each other and which each communicate by means of circulation tubes placed in series with the respective solenoid valves of one another e1, e2, e3 and e4 to the distributor D, wherein it further communicates, directly or by means of another circulation tube, not shown in the drawing, with the inlet to two other solenoid valves ep1 and ep2, the outlets of which connect to the inlet or outlet of a circulation pump P1 , which may be different from, but also the same as the circulation pump P of the extraction module ME, wherein, in this case, from these two said connection points, two further solenoid valves (ei and ec) are additionally connected in series in the fluid circuit of the extraction module ME, along the path of the intermediate circulation tubes 6, for passing the flow F respectively towards the thermostatically controlled heater 5 and the filtering capsule CF. If the circulation pump P1 or, as appropriate, the circulation pump P of the extraction module ME shown in Figure 2 is a two-way pump, one of the solenoid valves ep1, ep2 leading towards it from the distributor D can be removed together with the tubular connection on which it is located, and one of the solenoid valves ei or ec towards the thermostatically controlled heater 5 and the extraction capsule CE, namely the one on the same side of the circulation pump P1 or the circulation pump P of the extraction module ME to which the removed connection was coupled, may be omitted, being replaced by the intermediate circulation tube 6, which is shown in Figure 2 of the extraction module ME.

[0090] The power and control cables of the components shown in Figure 3, together with their connection socket to the automation panel TA, are not shown in the drawing.

[0091] As an example, an admission phase of a solvent from one of the adjacent vessels V1, V2, V3 or V4 into the extraction module ME and extraction vessel V assembly is given, wherein after the respective extraction phase a second phase of feeding the respective solvent back into the vessel from which it was extracted, with the active principles PA intended to be obtained from the extraction preparation PE in the respective extraction sequence:

[0092] - at the admission phase from the adjacent vessel V3 of the corresponding adjacent solvent S2 - the pump P1 or the pump P of the extraction module ME (as appropriate) is switched on simultaneously with the opening of the solenoid valves e3, ep1 and ec, respectively, of the one corresponding to the vessel used, i.e. that which connects the distributor D to the end of the pump on the side of the thermostatically controlled heater 5 and that which connects the other end of the pump P1 to the filtering capsule CF, in which case the solvent S2 reaches the main extraction vessel V which operates directly with the extraction module ME and the rest of the solenoid valves (e1, e2, e4, ep1 and ei) remain closed;

[0093] - after this, the programmed extraction phase follows, in which the solenoid valves ei and ec on the circuit of the intermediate circulation tubes 6 as well as the pump 5 are opened and the pump P1 - if any - and the solenoid valves ep1, ep2, e1, e2, and e4 corresponding to the adjacent vessels V1, V2, V3 and V4 are closed (the solenoid valve e3 corresponding to the vessel v3 being used can be either);

[0094] - at the phase of emptying the main extraction vessel V of the adjacent solvent S2 which is loaded with the extracted active principles - the pump P1 is started (if present, and if not, the pump P is started) simultaneously with the open position of the solenoid valves ei, ep1 and e3, i.e. that which connects the pump P1 to the thermostatically controlled heater 5, that which connects the other inlet of the pump P1 to the distributor D and that of the vessel being used, and the solenoid valves ec, ep2, e1, e2, and e4 are closed. Of course, the pairs of solenoid valves ei and ep1.1 as well as ec and ep1.2 can be replaced by three-port solenoid valves, one of which can be an inlet and the other two can be outlets which can be locked alternately.

[0095] The operation of the extraction module ME, both in the variant of single association with a single extraction vessel V and in that of adding the group of adjacent vessels V1, V2, V3 and V4, can be monitored by the presence on the respective circuits of fluid circulation sensors, not shown in the figures, which have connections in the automation panel TA and by means of which the correctness of the described phase starts and stops is provided, according to the patent.

[0096] The process according to the invention can be carried out with the claimed installation for the preparation of teas and other extracts presented above, namely in two different situations: b) - in a particular situation, the extraction module ME can operate in not one but several extraction phases, in which case for each phase the extraction module ME is in turn moved from the main extraction vessel V to different adjacent vessels V2, V3 and V4, each with the quantity and type of adjacent solvent S1, S2 and S3 provided, wherein we benefit from the simultaneous and synergistic action of the flow F at a certain temperature, which washes an extraction preparation PE located in maximum proximity to the metal wall 1 emitting ultrasound generated by one or more ultrasonic transducers TU while simultaneously performing sterilization and filtration by the means of removable filters 1.4 and / or a filtering bag 3 in each of the adjacent vessels V2, V3 and V4, in the same way as in the main extraction vessel V preferably made of stainless steel. The handling of the extraction preparation PE together with the extraction module ME may be manual or automated in that a mechanical system is used which moves either the extraction module ME or the extraction vessel V and the adjacent vessels V1, V2 and V3, or a combination thereof. c) - another situation is one in which the extraction vessel V with the position of the extraction module ME and of the adjacent vessels V1, V2, V3, and V4 is fixed, and the above mentioned action upon the extraction preparation PE continues in the consecutive phases of filling and emptying the main extraction vessel V with various quantities and / or various types of adjacent solvents S1, S2 and S3 exemplified in Figure 3, with the non-limiting example in the form of the respective total four successive phases. In this case, the maximum exploitation of the extraction preparation PE becomes fully automated.

[0097] It can be seen how some of the technical problems newly set forth in the description of the invention have been solved by the fact that the ultrasonic transducer TU in contact with the solvent S is a flat surface of a metal wall 1 with a much higher value than that of a pivot in industrial ultrasound sources. This is the surface of the emission area through contact of the metal wall 1 with the solvent S, simultaneously with a limited spacing, preferably at maximum proximity, of the extraction preparation PE with respect to the metal wall 1 and simultaneously with continuous washing of the extraction preparation PE with a flow F of solvent S, which speeds up the extraction of the active principles PA by their rapid dissipation from the volume of solvent S in contact with the extraction preparation PE to the entire volume thereof.

[0098] One of the core ideas according to which the extraction module ME is made and operates is the creation of a closed circuit of solvent S which is set in motion by the pump P or a controlled-flow agitator, and comes into contact with the thermostatically controlled heater 5 and with the extraction preparation PE which is under the direct and closest influence of the ultrasonic transducer TU, in which area the filtration and sterilization of the solvent S and of the active principles PA contained therein are carried out at the same time. d) Furthermore, in particular, the circulation pump P can be replaced by a controlled-flow agitator which can operate in the extraction vessel or any component of the extraction module through which the solvent can circulate. e) Furthermore, in particular, given the dimensions of the ultrasonic transducers, the dimension of the extraction preparation and the volume of the solvent, there may be situations in which the filtering capsule can be identical to the extraction vessel. f) Furthermore, in particular, the extraction module is further characterized in that,

[0099] - the metal wall 1 of the filtering capsule CF and / or the solvent S can be put in contact wherever it is located or on the path on which it circulates, including in or on the surface of the extraction vessel, with a passive cooler, i.e. provided with cooling fins, or an active cooler, i.e. further provided with a cooling medium, which cooler is not shown in the drawing, and which has the function of extracting from the solvent the excess temperature produced by the activity of the ultrasonic transducers. g) Furthermore, in particular, a variant of an immersible capsule which is not shown in the drawings is characterized in that, it is made in a simplified form, wherein the metal wall extends and encloses the ultrasonic transducers in an airtight inner space, the only connection with the exterior being constituted by the power wires, thus forming a support body on which the filtering bag containing the extraction preparation is fixed at the maximum proximity distance, wherein, functionally, the immersible capsule is partially or totally placed in the flow of the solvent.

[0100] For the purposes of the present invention, "compound / preparation" is understood to mean a starting material being used, which is a substance or a mixture of substances with a more or less complex composition, consisting of one or more different organic and / or inorganic elements, intended to be used for the purpose of obtaining one or more extracts.

[0101] "Maceration" is understood to mean a process resulting from keeping a preparation in a solvent at cold or room temperature, up to about 40 degrees Celsius, in order to extract its various components.

[0102] "Digestion" is understood to mean a process in the form of a macerate that is obtained between 40 and 60 degrees Celsius in order to release into the solvent the elements that separate from the preparation at temperatures above those of the macerate below 40 degrees.

[0103] "Brewing" is understood to mean a process obtained by infusing a preparation in order to extract the active principles it contains, between 60 and 95 degrees Celsius, which also sterilizes it by destroying, due to the thermal effect, most of the bacteria that can make the human body sick.

[0104] "Decoction" is understood to mean a process obtained by prolonged boiling of a prepared compound in order to extract the active principles that are not released or are released too little by previous processes.

[0105] "Tincturation" is understood to mean a process obtained by extraction in alcohol in various concentrations, from a preparation, of certain compounds consisting of organic and / or inorganic substances.

[0106] A "filtrate" is understood to mean a solution that has been filtered and no longer contains heterogeneous or suspended matter, without impurities and / or live microbes.

[0107] An "extract" is understood to mean a substance or mixture of substances prepared by concentrating products extracted from plant or animal matter.

[0108] A "cocktail" is understood to mean a beverage containing one or more types of alcohol and / or flavorings and / or one or more fruit juice liqueurs, sauces, honey, milk, cream or spices, etc. "Active principles" are understood to mean a substance or a mixture of substances with a therapeutic bioactive sanogenic effect, such as, but not limited to, alkaloids, glycosides, saponins, bitter principles, tannins, aromatic substances, volatile oils, essential oils, fatty oils, enzymes, vitamins, polyphenols, carotenoids, anthocyanins, albumins, tranferins, plant mucilages, antiseptics, antioxidants, mineral salts, etc.

[0109] "Ultrasonication" or "sonication" is understood to mean the bringing into contact of preparations with wavefronts of superaudible frequency in solvent, which causes by cavitation the creation of air bubbles in the center areas of the waves, where the pressure is low and then by explosion in the node areas where the pressure can exceed a thousand bars, which creates a rapid increase in the permeability of the cell membranes, leading to their destruction, and which also causes the death of single cell organisms present in the solvent (equivalent to sterilization). A lysis of the cells, the rupture of the cell membrane, occurs, which causes a speed and a yield of the extraction several times higher compared to the influence of the thermal agitation of the solvent molecules due to temperature. This phenomenon creates the possibility of low temperature extraction of bioactive compounds, which are often thermally unstable and are gradually destroyed by digestion, infusion and decoction.

[0110] "Maximum proximity" is understood to mean a minimum distance between the metal wall of the filtering capsule to which one or more ultrasonic transducers are attached and the preparation or compound undergoing extraction, with a maximum distance between them of preferably 15 millimeters for each 10 watts of emitting power of one or more ultrasonic transducers in combined value.

[0111] The most important bioactive substances are the catalysts of cellular metabolic processes called enzymes, their regulators called vitamins and antioxidants, which annihilate free radicals - destroyers of immunity and protection of cell replication of DNA in chromosomes, in short, factors that shorten the life of the human body.

[0112] The filtering capsule CF can be produced with the body C made of stainless-steel sheet of 0.2-1 mm thickness and with the dimensions of 120x80x80, with the dimension of a removable filter 1.4 of 75x75 mm2and a solvent circulation opening with a diameter of 6-25 mm and a filtering bag with inside dimensions of 70x70mm2, made of stainless- steel mesh with a mesh of 0.3-0.7 mm, which when full can have a thickness of 10-40 mm. The removable filter 1.4 may preferably be made of stainless-steel mesh, e.g. of AISI304 type, with 0.3-1 mm thread size and 0.3-0.8 mm mesh average diameter, but other materials resistant to alkalis and acids and to temperatures of at least 100 °C, such as some textiles, may also be used.

[0113] The distributor D may be of the commercially available five-way solenoid valve type.

[0114] Usable ultrasonic transducers TU may be of the BJQXPDT type with a maximum input power of 15-50 W or of the CN-4038-45LBP8 / P4 type with a maximum input power of 120 W, with ultrasonic emission frequency of 20-40 KHz, representing piezoelectric quartz plates fed with pulsating direct current supplied by the ultrasound generator 4, which causes the quartz crystal to vibrate perpendicular to the plane of the quartz plate.

[0115] The minimum velocity of the flow F of solvent S, which may be water, an alcoholic or fatty solution, etc., is preferably 10-20 mm / sec.

[0116] The pump P for circulating the flow F of solvent / solvents may be of the 1 -10 liter / min flow rate type, such as of the ZC-A250, ZC-T40 or JT-750 series with 12 V power supply.

Claims

Claims1. An installation for extracting bioactive sanogenic substances from plant or animal cells by means of ultrasound, comprising an extraction module (M) for extracting bioactive sanogenic substances from an extraction preparation (PE) for the purpose of optimized exploitation thereof, comprising, joined by circuit elements such as fluid circulation tubes and solenoid valves, a pump (P) which may be from a basic extraction technology or an in-house pump (P1) connected to a distributor (D), all controlled manually or by an inhouse automated program or associated with the basic extraction installation, some inlets (IN) and outlets (IE) for the liquid forming a solvent (S) for the extraction preparation (PE), which are connected to the inside of a main extraction vessel (V), characterized in that to the distributor (D) there are further connected 2-4 adjacent vessels (V1, V2, V3 and V4) containing one or more adjacent solvents (S1, S2 and S3), which may be identical to or different from the solvent (S) in the main extraction vessel (V) in terms of composition, mass and adjacent temperatures (T1 , T2 and T3), wherein for the extraction of the bioactive sanogenic substances (PA) from the extraction preparation (PE) by means of the action of ultrasound and by means of the solvent (S) taken from the main vessel (V) and / or from an adjacent vessel (V1, V2, V3 or V4), there is provided a filtering capsule (CF) comprising the extraction preparation (PE) in a filtering bag (3) located in maximum proximity to a surface of a flat metal wall (1), which is in turn in contact with both the solvent (S) circulated through the filtering capsule (CF) and the extraction preparation (PE), wherein the other surface of the metal wall (1) is in contact with the flat surface of one or more ultrasonic transducers (TU) emitting ultrasonic fronts, which are connected to an ultrasound generator (4), wherein the gathering of the ultrasonically released bioactive sanogenic substances is carried out by successive operations of emptying and refilling the respective extraction vessel with adjacent solvents (S1, S2 and S3), wherein the flow (F) of solvent (S) incorporating bioactive substances extracted from the extraction preparation (PE) is further circulated through some removable filters (1.4) or through a thermostatically controlled heater (5).

2. Installation for extracting bioactive sanogenic substances, according to claim 1 or 2, characterized in that the extraction module (ME) further comprises, on the pump (P) circuit for circulating the liquids and through the filtering capsule (CF), a thermostatically controlled heater (5) connected directly or through intermediate circulation tubes (6), so that a solvent (S) can circulate through this chain of components, wherein the free ends of this chain can communicate through the heater tube (6.1) and the capsule tube (6.2),respectively, with the volume of a solvent (S) contained inside a main extraction vessel (V), which may be omitted if necessary, being replaced, by means of circuit elements not shown in the drawings, by closing the pump (P) circuit with any of the adjacent vessels (V1 , V2, V3 or V4).

3. Installation for extracting bioactive sanogenic substances, according to claim 1 or 2, characterized in that it comprises the filtering capsule (CF) consisting of a body (C) of parallelepipedal or cylindrical shape or a combination of the two, wherein at the ends of the larger size of the body (C) there is a removable wall (1.1) of flat or curved shape, which may each have one or more outlet openings (1.2) to which, as required, tubes for the circulation of the liquid / liquids acting as solvent (S) may be connected, and the removable walls (1.1) may, as required, each be doubled by a removable filter (1.4) arranged inwards towards the body (C), which may also contain one or more side and / or top closing walls (1.3) which are also fixed and / or removable and of suitable shapes in order to achieve partial or total closing of the body (C), wherein the metal wall (1) adjacent to the side closing walls (1.3) has at least one flat portion, preferably with a surface in which at least one circle with a diameter preferably greater than 70 mm can be inscribed, and the extraction preparation (PE) is stored in the inner space of the filtering capsule (CF) between the removable filters (1.4), in maximum proximity to the metal wall (1), preferably in a filtering bag (3).

4. Installation for extracting bioactive sanogenic substances, according to claim 1 , 2 or 3, characterized in that the ultrasonic transducers (TU) are planar in shape and have electrically insulated supply wires (2), with the insulation resistant to a wide range of liquids such as basic or acidic solutions or alcohols, fats, etc. and to temperatures above 100*0, wherein the filtering bag (3) can be closed and opened in order to contain the extraction preparation (PE), its surface being in contact with the flow (F) of a solvent (S) which flows through the interior of the body (C) and contains dissolved and / or suspended bioactive sanogenic substances (PA) extracted by ultrasonication from the preparation (PE).

5. Installation for extracting bioactive sanogenic substances, according to claim 1 , 2, 3 or 4, characterized in that it further comprises an automation panel (TA) comprising an ultrasound generator (4) connected by means of supply wires (2) to the ultrasound transducer (TU), and elements providing the power supply for controlling the circuit elements: pump (P), thermostatically controlled heater (5), various solenoid valves, etc, wherein the automation panel (TA) can be programmed by means of WI-FI or / andBluetooth and it programs the starting and stopping times of the circulation of liquids as well as their temperatures, and also the operating times and emitting powers of the ultrasound generator, and which also has a set of buttons and displays and signalling means for manual programming of all these sequences of operations.

6. Installation for extracting bioactive sanogenic substances, according to claim 1 , 2, 3, 4 or 5, characterized in that the extraction module (ME) further comprises a passive finned cooler or an active cooler which is placed in contact with the metal wall (1) of the filtering capsule (CF) and / or with the solvent (S), with the purpose of extracting the excess temperature produced by the activity of the ultrasonic transducer(s) (TU).

7. Installation for extracting bioactive sanogenic substances, according to claim 1 , 2, 4, 5 or 6, characterized in that the extraction module (ME) comprises the metal wall (1) of the filtering capsule (CF) which is extended in order to enclose in an airtight interior space the ultrasonic transducers (TU) connected to the outside by supply wires (2), and in order to form a submersible capsule-type body on which the filtering bag (3) containing the extraction preparation (PE) is fixed, wherein the submersible capsule is placed partially or totally in the flow (F) of the solvent (S).

8. A process for extracting bioactive sanogenic substances from plant or animal cells by means of ultrasound from an extraction preparation (PE), characterized in that the extraction preparation (PE) is subjected to the simultaneous action of at least one suitable solvent flow (F), at a maximum proximity depending on the strength of a ultrasonic field and a thermal field, stabilized by the combined action of a heating element and a cooling element, with automatic control of the solvent temperature so that in the action range of the ultrasonic field the temperature thereof is close to the recommended extraction temperature but without exceeding this value, wherein the heating of the solvent flow (F) is achieved by a thermostatically controlled heater (5), and the ultrasonic field is achieved with ultrasonic transducers (TU) attached with the flat surface to a metal wall (1) in contact with the solvent flow (F) and with a filtering bag (3) containing the extraction preparation (PE), which is distributed adjacent to the entire surface of the metal wall (1) and in maximum proximity thereto, for maximum extraction efficiency of the bioactive sanogenic substances

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