Cryogenic apparatus, cryogenic method, and cryosurgical instrument

By designing a freezing device including a freezing head, an evaporation part and a liquid storage assembly, the temperature of the freezing head is reduced by evaporation and capillary phenomena, the problem that the existing freezing head cannot maintain low temperature for a long time is solved, and the efficiency and reliability of the freezing operation are improved.

WO2025118324A1PCT designated stage expired Publication Date: 2025-06-12SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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Patent Information

Application Number
PCT/CN2023/138265
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-12-08
Filing Date
2023-12-12
Publication Date
2025-06-12

AI Technical Summary

Technical Problem

The existing freezing heads cannot maintain low temperature for a long time, resulting in high difficulty in freezing operation and low efficiency.

Method used

A refrigeration device is designed, including a refrigeration head, an evaporator and a liquid storage assembly. A storage tank containing the refrigerant is provided on the evaporation member, and a capillary tube is provided on the refrigerant head, which is in communication with the storage tank, and is used to transport the refrigerant to the refrigerant head, and the temperature of the refrigerant head is reduced through evaporation and capillary phenomena.

Benefits of technology

It is realized that the freezing head can still maintain a low temperature when the surrounding environment is high, reducing the difficulty of operation and saving time and energy.

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Abstract

Provided are a cryogenic apparatus, a cryogenic method, and a cryosurgical instrument. The cryogenic apparatus comprises a cryoprobe (100), an evaporation member (200), and a liquid storage assembly (400). The evaporation member (200) is connected to the cryoprobe (100). The evaporation member (200) is provided with an accommodating tank for accommodating a cryogenic liquid. The cryogenic liquid in the accommodating tank volatilizes, lowering the temperature of the evaporation member (200) and the cryoprobe (100). The cryoprobe (100) is provided with a capillary tube (110), and the capillary tube (110) is in communication with the accommodating tank, so that part of the cryogenic liquid in the accommodating tank is conveyed to the cryoprobe (100) by means of the capillary tube (110). The cryogenic liquid conveyed to the cryoprobe (100) volatilizes and absorbs heat, further lowering the temperature of the cryoprobe (100), so that the cryoprobe (100) can still stably meet the expected temperature requirement when the ambient temperature is relatively high. The present invention reduces operational difficulty, saving both time and effort.
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Description

Freezing device, freezing method and cryosurgical instrument Technical Field

[0001] The present invention relates to the technical field of medical surgical instruments, and in particular to a freezing device, a freezing method and a cryosurgical instrument. Background Art

[0002] In some work that requires local low temperature treatment of a certain interface, such as the frostbite operation within a 1mm diameter range of the animal skull, it is necessary to ensure the normal body temperature of the animal as a whole, and to stably maintain a temperature of minus 100°C in a small area at a designated position on the skull to cause local frostbite. Therefore, a freezing device is needed.

[0003] In the prior art, a 1mm diameter copper rod is usually immersed in liquid nitrogen for a period of time to allow the copper rod to reach -100°C, and then the copper rod is taken out and transferred to the surface of the animal skull in a room temperature environment and kept there for 2 seconds to create a local brain frostbite model. Since the surface temperature of the copper rod continues to rise after it is taken out of liquid nitrogen and returned to a room temperature environment, it is actually measured that the time it takes for the 1mm diameter copper rod to reach -100°C is about 12 seconds from the time it leaves the liquid nitrogen to the time it reaches -100°C, and the temperature thereafter is no longer below -100°C; and since the copper rod will gain more heat energy when it contacts the surface of the skull, causing the copper rod to heat up rapidly, it may cause the skull surface to fail to reach -100°C. Due to the above obvious defects, during the freezing operation, the operator is often required to operate quickly, but rapid operation is prone to operational errors, resulting in poor local frostbite effects.

[0004] Therefore, the existing technology needs to be improved and developed.

[0005] Summary of the Invention

[0006] In view of the above-mentioned defects of the prior art, the object of the present invention is to provide a freezing device, a freezing method and a cryosurgical instrument to solve the technical problem that the existing freezing head cannot maintain a low temperature for a long time.

[0007] The technical solutions adopted by the present invention to solve the above problems are as follows:

[0008] A freezing device, comprising: a freezing head, wherein the freezing head is provided with a capillary tube;

[0009] an evaporating element connected to the freezing head, wherein the evaporating element is provided with a receiving tank for holding the freezing liquid, and the capillary tube is connected to the receiving tank for transporting the freezing liquid in the receiving tank to the freezing head;

[0010] A liquid storage component is provided with a storage cavity for accommodating freezing liquid inside the liquid storage component, and the storage cavity is communicated with the accommodating tank and is used to provide freezing liquid to the accommodating tank.

[0011] Optionally, a plurality of capillaries are provided, one end of each capillary is communicated with the receiving groove, and the other end of each capillary extends to an end of the freezing head away from the evaporating element.

[0012] Optionally, the evaporator is cylindrical, the receiving groove is provided on the upper end surface of the evaporator, and the receiving groove is a cylindrical groove with an upper opening; a connecting port connected to the receiving groove is provided on the side wall of the evaporator, the capillary is connected to the receiving groove through the connecting port, and the liquid storage assembly is connected to the receiving groove through the upper opening of the receiving groove.

[0013] Optionally, the refrigeration device further includes a positioning member connected to the evaporation member.

[0014] Optionally, the liquid storage assembly includes a refrigerant guide tube, a refrigerant storage bottle and a flow control device, the storage cavity is provided in the refrigerant storage bottle, one end of the refrigerant guide tube is connected to the storage cavity, and the other end is connected to the liquid inlet end of the flow control device, and the liquid outlet end of the flow control device is connected to the receiving tank.

[0015] Optionally, the refrigerant guide tube includes a flexible refrigerant guide tube.

[0016] Optionally, the freezing liquid storage bottle includes an insulated inner bottle and a thermal insulation layer, and the thermal insulation layer is arranged on the outer surface of the insulated inner bottle; and / or the freezing liquid guide tube includes a guide inner tube and a guide insulation layer, and the guide insulation layer is arranged on the outer surface of the guide inner tube.

[0017] Optionally, the freezing device further includes a handle, which is provided on the liquid storage assembly.

[0018] A freezing method for a freezing device as described in any one of the above items, characterized in that it comprises the steps of:

[0019] Move the freezing head to the position to be frozen and fix it;

[0020] The refrigerant in the liquid storage assembly is transported to the evaporator until the liquid level of the refrigerant in the evaporator submerges the connection port between the capillary tube and the receiving tank.

[0021] A cryosurgical instrument, wherein the cryosurgical instrument comprises the freezing device as described in any one of the above items.

[0022] In summary, the beneficial effects of the present invention are:

[0023] The freezing device of the present invention includes a freezing head, an evaporating element and a liquid storage component. The evaporating element is connected to the freezing head. The evaporating element is provided with a receiving tank for accommodating freezing liquid. The freezing liquid in the receiving tank evaporates and reduces the temperature of the evaporating element and the freezing head. A capillary is provided on the freezing head, and the capillary is connected to the receiving tank, so that part of the freezing liquid in the receiving tank is transported to the freezing head through the capillary. The freezing liquid transported to the freezing head evaporates and absorbs heat, further reducing the temperature of the freezing head, so that the freezing head can still stably maintain the expected temperature requirements when the surrounding environment has a high temperature, reducing the difficulty of operation, and saving time and energy. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the prior art. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0025] FIG1 is a schematic structural diagram of a refrigeration device according to the present invention;

[0026] FIG2 is a cross-sectional view of a refrigeration device according to the present invention;

[0027] FIG3 is a cross-sectional view of a freezing head according to the present invention;

[0028] FIG4 is a flow chart of the freezing method of the present invention.

[0029] Among them: 100, freezing head; 110, capillary; 200, evaporation part; 400, liquid storage component; 410, freezing liquid guide tube; 411, guide inner tube; 412, guide insulation layer; 420, freezing liquid storage bottle; 421, insulation inner bottle; 422, insulation layer; 430, flow control device; 431, liquid introduction nozzle; 432, flow control switch; 500, handle; 600, positioning part. DETAILED DESCRIPTION

[0030] In order to enable those skilled in the art to better understand the solutions of the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, other embodiments obtained by those skilled in the art without making any creative work shall fall within the scope of protection of the present invention.

[0031] Referring to Figures 1 and 3, in one embodiment of the present invention, a freezing device is disclosed, including a freezing head 100, an evaporator 200 and a liquid storage assembly 400, wherein a capillary tube 110 is provided on the freezing head 100; the evaporator 200 is connected to the freezing head 100, and the evaporator 200 is provided with a receiving tank for placing the freezing liquid; the capillary tube 110 is provided on the freezing head 100, and one end of the capillary tube 110 is communicated with the receiving tank for transporting part of the freezing liquid in the receiving tank to the freezing head 100; the liquid storage assembly 400 is provided with a storage chamber for accommodating the freezing liquid inside, and the storage chamber is communicated with the receiving tank for providing the freezing liquid to the receiving tank.

[0032] The coolant in this embodiment is liquid nitrogen, which has a boiling point of -196°C and can be rapidly vaporized under normal pressure. The liquid nitrogen absorbs a large amount of heat during the vaporization process, thereby reducing the surrounding temperature.

[0033] Specifically, liquid nitrogen is stored in the liquid reservoir assembly 400. When the cryohead 100 needs to maintain a low temperature, the operator tilts the liquid reservoir assembly 400, causing the liquid nitrogen in the liquid reservoir assembly 400 to enter the holding tank on the evaporator 200. The liquid nitrogen in the holding tank rapidly vaporizes, absorbing a large amount of heat during vaporization, thereby lowering the temperature of the evaporator 200. Since the cryohead 100 is connected to the evaporator 200, the temperature of the cryohead 100 also decreases. It should be emphasized that since the cryohead 100 is provided with a capillary tube 110, and the inlet of the capillary tube 110 is connected to the holding tank, when the liquid nitrogen in the liquid reservoir assembly 400 enters the holding tank, the capillary tube 110 contacts the liquid nitrogen. According to the principle of capillary action, the capillary tube 110 transports the liquid nitrogen in the holding tank to the cryohead 100. The liquid nitrogen transported to the cryohead 100 vaporizes and absorbs heat, further lowering the temperature of the cryohead 100.

[0034] The principle of capillary action in this embodiment is that the surface of a liquid is like a stretched rubber membrane. If the liquid surface is curved, it tends to flatten. Therefore, the concave liquid surface exerts a pulling force on the liquid below, while the convex liquid surface exerts a compressive force on the liquid below. Capillary action is caused by surface tension. The concave surface of the wetting liquid in capillary tube 110 exerts a pulling force on the liquid below, causing it to rise along the tube wall. When the upward pulling force equals the weight of the liquid column within the tube, the liquid within the tube stops rising, reaching equilibrium. For example, water rises in a thin glass tube because it wets glass.

[0035] In this embodiment, an evaporator 200 is provided to lower the temperature of the freezing head 100 by utilizing the principle of liquid nitrogen vaporization and heat absorption. A capillary tube 110 is provided to transport liquid nitrogen to the freezing head 100 for vaporization and heat absorption by utilizing the capillary principle, thereby further lowering the temperature of the freezing head 100 and extending the time for the freezing head 100 to maintain a low temperature, thereby reducing the difficulty of the freezing operation and saving time and energy, so that the freezing head 100 can still stably maintain the expected temperature requirements when the surrounding temperature is higher.

[0036] Please refer to FIG. 2 . There are multiple capillaries 110 . One end of the capillary tube 110 is connected to the receiving tank, and the other end of the capillary tube 110 extends to an end of the freezing head 100 away from the evaporator 200 .

[0037] In this embodiment, the capillary tube 110 can be provided as one or more capillaries, and the number of capillaries 110 can be determined according to the amount of cryogenic liquid to be transported. The capillary tube 110 can be provided on the cryohead 100 in various ways, such as by providing one or more channels at intervals within the cryohead 100 and then providing the capillaries 110 in the channels; or by directly providing pores within the cryohead 100, wherein the pores serve as the capillaries 110 in this embodiment.

[0038] During the freezing operation, the operator places the freezing head 100 in liquid nitrogen for cooling. When the temperature of the freezing head 100 reaches the required temperature, the freezing head 100 is taken out and transferred to the surface of the experimental object and stays there for a certain period of time to create a local frostbite model. During the freezing operation, the end of the freezing head 100 away from the evaporator 200 is the operating end.

[0039] When the liquid nitrogen on the evaporator 200 vaporizes and absorbs heat, the operating end of the freezing head 100 is far away from the evaporator 200, so the cooling effect of the operating end of the freezing head 100 is affected to a certain extent. In addition, when the operating end of the freezing head 100 contacts the frozen object, the heat on the frozen object will be transferred to the operating end of the freezing head 100, causing the temperature of the operating end of the freezing head 100 to rise. In this embodiment, a small amount of liquid nitrogen in the holding tank is transported to the operating end of the freezing head 100 through the capillary action of the capillary tube 110. The liquid nitrogen transported to the operating end of the freezing head 100 vaporizes and absorbs heat, thereby reducing the temperature of the operating end of the freezing head 100, making the heat exchange and cooling of the freezing head 100 more sufficient.

[0040] In this embodiment, the evaporator 200 is cylindrical, and the receiving groove is provided on the upper end surface of the evaporator 200, and the receiving groove is a cylindrical groove with an upper opening; a connecting port connected to the receiving groove is provided on the side wall of the evaporator 200, and the capillary 110 is connected to the receiving groove through the connecting port, and the liquid storage component 400 is connected to the receiving groove through the upper opening of the receiving groove.

[0041] Specifically, the end of the capillary tube 110 away from the operating end of the freezing head 100 is the liquid inlet end, and the liquid inlet end is connected to the connecting port. When the operator tilts the liquid storage assembly 400, the liquid nitrogen in the liquid storage assembly 400 enters the holding tank from the upper opening of the holding tank. When the liquid nitrogen in the holding tank submerges the liquid inlet end of the capillary tube 110, the liquid nitrogen enters the capillary tube 110 through the liquid inlet end of the capillary tube 110.

[0042] In this embodiment, the evaporation member 200 is configured to be cylindrical, which can better utilize space and reduce the volume of the evaporation member 200; an opening is provided above the receiving tank. On the one hand, the pressure in the receiving tank can be released to avoid danger caused by excessive air pressure in the receiving tank. On the other hand, the opening is provided above the receiving tank. The operator can observe the amount of liquid nitrogen in the receiving tank through the opening above the receiving tank, which facilitates operation.

[0043] In a feasible embodiment, the evaporating element 200 is further provided with a side opening communicating with the receiving tank, and the liquid storage assembly 400 can be communicated with the receiving tank through the side opening.

[0044] In this embodiment, the cross section of the freezing head 100 gradually decreases in a direction away from the evaporation element 200 .

[0045] In this embodiment, the cross-section of the end of the cryohead 100 near the evaporator 200 is larger, ensuring efficient heat transfer between the cryohead 100 and the evaporator 200. However, the operating end of the cryohead 100 needs to contact the frozen object, causing localized frostbite. To allow for more precise operation, the operating end of the cryohead 100 is typically smaller to avoid frostbite on areas outside the target area. In this embodiment, the cross-section of the cryohead 100 gradually decreases as it moves away from the evaporator 200. This ensures that the operating end can be designed to be sufficiently small as needed while also ensuring sufficient heat exchange between the cryohead 100 and the evaporator 200.

[0046] In this embodiment, the freezing head 100 and the evaporation element 200 are integrally formed.

[0047] The one-piece molding structure refers to connecting multiple parts into a whole through a molding process. The one-piece molding structure can not only improve the strength and rigidity of the structure, but also reduce the number of connecting parts, thereby reducing thermal resistance and obstacles in the heat conduction process, improving heat dissipation efficiency, and extending the low temperature time of the freezing head 100.

[0048] In this embodiment, the freezing head 100 includes a pure copper freezing head 100 or a stainless steel freezing head 100 ; and / or the evaporation element 200 includes a pure copper evaporation element 200 or a stainless steel evaporation element 200 .

[0049] Specifically, pure copper and stainless steel both have high thermal conductivity, allowing them to quickly transfer heat in the cryostat 100, which requires efficient heat conduction. It is important to note that pure copper, due to its metallic properties, is easier to process and can be easily fabricated into cryostat 100s of various shapes and sizes. Furthermore, pure copper also offers excellent antifreeze properties.

[0050] In this embodiment, the refrigeration device further includes a positioning member 600 , and the positioning member 600 is connected to the evaporation member 200 .

[0051] Specifically, one end of the positioning member 600 is fixedly connected to the evaporator 200, and the other end extends away from the evaporator 200, for being held by hand or connected to an external control device. Furthermore, the flow control device 430 is connected to the positioning member 600. Since the cryohead 100 is connected to the evaporator 200, which in turn is connected to the positioning member 600, the cryohead 100 can be moved by moving the positioning member 600, allowing the cryohead 100 to be positioned in a suitable position. The positioning member 600 allows for flexible and precise positioning of the cryohead 100.

[0052] In order to prevent the evaporator 200 from exchanging heat with the outside through the positioning member 600, which may cause the temperature of the positioning member 600 to be too low, the positioning member 600 is made of a material with slow heat conduction, such as plastic or other heat-insulating materials.

[0053] In this embodiment, the liquid storage assembly 400 includes a refrigerant guide tube 410, a refrigerant storage bottle 420 and a flow control device 430. The storage cavity is provided in the refrigerant storage bottle 420. One end of the refrigerant guide tube 410 is connected to the storage cavity, and the other end is connected to the liquid inlet end of the flow control device 430. The liquid outlet end of the flow control device 430 is connected to the receiving tank.

[0054] Please refer to Figure 2. The flow control device 430 in this embodiment includes a liquid introduction nozzle 431 and a flow control switch 432. The liquid introduction nozzle 431 is fixedly connected to the positioning member 600, and one end of the liquid introduction nozzle 431 is connected to the freezing liquid guide tube 410, and the other end is aligned with the upper opening of the containing tank. The flow control switch 432 is provided on the liquid introduction nozzle 431 for controlling the flow of liquid nitrogen.

[0055] Specifically, when the operator tilts the cryogenic liquid storage bottle 420, the liquid nitrogen in the cryogenic liquid storage bottle 420 enters the liquid inlet nozzle 431 through the cryogenic liquid guide tube 410. By controlling the opening of the flow control switch 432, the flow rate of the liquid nitrogen entering the holding tank can be adjusted. The liquid nitrogen flowing through the liquid inlet nozzle 431 enters the holding tank from the upper opening of the holding tank.

[0056] Since the inner diameter of the freezing liquid guide tube 410 is smaller than the inner diameter of the freezing liquid storage bottle 420 , the operator can conveniently control the flow rate of the liquid nitrogen, thereby better controlling the speed and amount of pouring out the liquid nitrogen.

[0057] In this embodiment, the refrigerant liquid guide tube 410 includes a flexible refrigerant liquid guide tube. The flexible refrigerant liquid guide tube is made of a flexible material and can be bent, so that the operator can flexibly position the freezing head and is easy to use.

[0058] Please refer to Figure 2, the freezing liquid storage bottle 420 includes an insulated inner bottle 421 and a thermal insulation layer 422, and the thermal insulation layer 422 is arranged on the outer surface of the insulated inner bottle 421; and / or, the freezing liquid guide tube 410 includes a guide inner tube 411 and a guide insulation layer 412, and the guide insulation layer 412 is arranged on the outer surface of the guide inner tube 411.

[0059] Specifically, the insulated inner bottle 421 includes a vacuum insulation tube, which is composed of two layers of containers, an inner and outer container. The storage cavity is provided within the inner layer, and the space between the inner and outer layers is evacuated to effectively reduce heat loss, thereby achieving a highly effective insulation effect. In this embodiment, a thermal insulation layer 422 is also provided on the outside of the vacuum tube, further improving the insulation effect of the frozen liquid storage bottle 420. Correspondingly, the guide inner tube 411 also includes a vacuum insulation tube, and a guide insulation layer 412 is provided on the outside of the vacuum insulation tube, thereby improving the insulation effect of the frozen liquid guide tube 410.

[0060] In this embodiment, the thermal insulation inner bottle 421 and the guide inner tube 411 are integrally formed, and the thermal insulation layer 422 and the guide insulation layer 412 are integrally formed. Providing the thermal insulation inner bottle 421 and the guide inner tube 411 as an integrally formed structure not only improves the strength and rigidity of the structure, but also reduces the number of sealing components, thereby reducing thermal resistance and obstacles in the heat conduction process, improving heat dissipation efficiency, and extending the low-temperature period of the cryohead 100.

[0061] In this embodiment, the refrigerant liquid guide pipe 410 is detachably connected to the evaporator 200 .

[0062] During the manufacturing process of the freezing model, different freezing objects require different freezing areas, so different sizes of freezing heads 100 need to be replaced. The evaporator 200 and the freezing head 100 in this embodiment are an integrated molding structure. Therefore, when replacing the freezing head 100, the evaporator 200 and the freezing head 100 are removed from the freezing liquid guide tube 410 and replaced with different models of freezing heads 100 and evaporator 200, making the use of the freezing device more convenient and having a wider range of applications.

[0063] In this embodiment, the freezing device further includes a handle 500 , which is disposed on the liquid storage assembly 400 .

[0064] Providing a handle 500 can improve the comfort and stability of the liquid storage component 400, and make it more convenient for operators during the freezing process. In order to prevent the liquid storage component 400 from exchanging heat with the outside through the handle 500, thereby causing the temperature of the handle 500 to be too low, the handle 500 is made of a material with slow heat conduction, such as a wooden stick or other insulating materials.

[0065] As another embodiment of the present application, referring to FIG4 , a freezing method is also disclosed, which is used for the freezing device as described above, comprising the steps of:

[0066] S100, moving the freezing head to the position to be frozen and fixing it.

[0067] S200: transporting the refrigerant in the liquid storage assembly into the evaporator until the liquid level of the refrigerant in the evaporator submerges the connection port between the capillary tube and the receiving tank.

[0068] Specifically, before the step of moving the freezing head to the position to be frozen and fixing it, the method further includes: placing the freezing head in liquid nitrogen until the temperature of the freezing head reaches -100° C. and then taking out the freezing head.

[0069] The freezing position described in this embodiment is the attachment of the surface of the freezing object or directly contacting the freezing object. In this embodiment, the freezing device can be controlled by an external device or manually operated.

[0070] Since the temperature of the freezing head gradually increases after it is taken out of the liquid nitrogen, and the temperature of the freezing head also increases when it comes into contact with the frozen object, in this embodiment, the freezing liquid in the liquid storage component is transported to the evaporator, and the freezing liquid in the evaporator vaporizes and absorbs heat to cool the freezing head. Moreover, when the liquid level of the freezing liquid in the evaporator is above the connection port of the capillary tube with the receiving tank, the freezing liquid in the receiving tank enters the freezing head through the connecting hole, and the freezing liquid in the freezing head evaporates, further reducing the temperature of the freezing head. This ensures that the freezing head can still stably maintain the expected temperature requirements when the surrounding environment has a high temperature, thereby reducing the difficulty of operation and saving time and energy.

[0071] As another embodiment of the present application, a cryosurgical instrument is also disclosed, wherein the cryosurgical instrument is provided with any of the above-described freezing devices, which can stably maintain a temperature of -100°C in a small area of ​​a target location to cause local frostbite.

[0072] In summary, the freezing device of this embodiment includes a freezing head 100, an evaporating element 200 and a liquid storage assembly 400. The evaporating element 200 is connected to the freezing head 100. The evaporating element 200 is provided with a receiving tank for accommodating refrigerant. The refrigerant in the receiving tank evaporates and reduces the temperature of the evaporating element 200 and the freezing head 100; a capillary 110 is provided on the freezing head 100, and the capillary 110 is connected to the receiving tank, so that part of the refrigerant in the receiving tank is transported to the freezing head 100 through the capillary 110 to evaporate and absorb heat, further reducing the temperature of the freezing head 100, so that the freezing head 100 can still stably maintain the expected temperature requirements when the surrounding environment has a high temperature, reducing the difficulty of operation, and saving time and energy.

[0073] It should be noted that, unless there is any conflict, the embodiments and features in the embodiments of this application can be combined with each other.

[0074] It should be noted that the present invention uses a freezing device, a freezing method and a cryosurgical instrument as an example to introduce the specific structure and working principle of the present invention, but the application of this embodiment is not limited to a freezing device, a freezing method and a cryosurgical instrument, and can also be applied to the production and use of other similar workpieces.

[0075] It should be understood that the present invention is not limited to the exact construction described above and shown in the drawings, and that various modifications and changes may be made without departing from the scope thereof. The scope of the present invention is limited only by the appended claims.

[0076] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A refrigeration device, characterized in that, it includes: a refrigeration head, on which a capillary tube is provided; an evaporation member, connected to the refrigeration head, on which a receiving groove for containing a refrigerant is provided, and the capillary tube communicates with the receiving groove for transporting the refrigerant in the receiving groove to the refrigeration head; a liquid storage assembly, inside which a storage cavity for containing the refrigerant is provided, and the storage cavity communicates with the receiving groove for supplying the refrigerant to the receiving groove.

2. The refrigeration device according to claim 1, characterized in that, a plurality of capillary tubes are provided, one end of the capillary tube communicates with the receiving groove, and the other end of the capillary tube extends to the end of the refrigeration head away from the evaporation member.

3. The refrigeration device according to claim 1, characterized in that, the evaporation member is in a cylindrical shape, the receiving groove is provided on the upper end surface of the evaporation member, and the receiving groove is a cylindrical groove with an opening at the top; a connection port communicating with the receiving groove is provided on the side wall of the evaporation member, the capillary tube communicates with the receiving groove through the connection port, and the liquid storage assembly communicates with the receiving groove through the opening at the top of the receiving groove.

4. The refrigeration device according to claim 1, characterized in that, the refrigeration device further includes a positioning member, and the positioning member is connected to the evaporation member.

5. The refrigeration device according to claim 1, characterized in that, the liquid storage assembly includes a refrigerant guiding tube, a refrigerant storage bottle and a flow control device, the storage cavity is provided inside the refrigerant storage bottle, one end of the refrigerant guiding tube is connected to the storage cavity, the other end is connected to the liquid inlet end of the flow control device, and the liquid outlet end of the flow control device is connected to the receiving groove.

6. The refrigeration device according to claim 5, characterized in that, the refrigerant guiding tube includes a flexible refrigerant guiding tube.

7. The refrigeration device according to claim 5, characterized in that, the refrigerant storage bottle includes a heat-insulating inner bottle and a heat-insulating layer, and the heat-insulating layer is provided on the outer surface of the heat-insulating inner bottle; and / or, the refrigerant guiding tube includes a guiding inner tube and a guiding heat-insulating layer, and the guiding heat-insulating layer is provided on the outer surface of the guiding inner tube.

8. The refrigeration device according to claim 1, characterized in that, the refrigeration device further includes a handle, and the handle is provided on the liquid storage assembly.

9. A refrigeration method for a refrigeration device according to any one of claims 1 to 8, characterized in that, it includes the steps of: moving the refrigeration head to the position to be refrigerated and fixing it; transporting the refrigerant in the liquid storage assembly into the evaporation member until the liquid level of the refrigerant in the evaporation member exceeds the connection port of the capillary tube with the receiving groove.

10. A cryosurgical instrument, characterized in that, it includes a refrigeration device according to any one of claims 1 to 8.

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