Intermittent suction thrombus aspiration pump system

Abstract

Provided is an intermittent suction thrombus aspiration pump system, which comprises: a suction catheter (1), a flow restrictor (2), a first pressure sensor (4), a second pressure sensor (3), a constant displacement pump (5), a pinch valve (6), a collection container (7), a third pressure sensor (8), a negative pressure regulating valve (9), and a negative pressure pump (10). The suction catheter (1), the first pressure sensor (4), the flow restrictor (2), the second pressure sensor (3), the pinch valve (6), the collection container (7), the third pressure sensor (8), the negative pressure regulating valve (9), and the negative pressure pump (10) are sequentially connected, and two ends of the constant displacement pump (5) are connected to two ends of the pinch valve (6), respectively. The pressure difference can be actively increased without increasing the negative pressure output by the negative pressure pump (10), achieving instant suction of thrombi.

Description

Intermittent thrombus aspiration pump system Technical Field

[0001] The present invention relates to the technical field of intravascular thrombus aspiration, and in particular to an intermittent thrombus aspiration pump system. Background Art

[0002] Thrombosis is a common clinical condition. Its main hazards include: 1) blockage of the blood vessel lumen, resulting in distal blood flow obstruction; and 2) detachment of the thrombus, leading to serious harms such as pulmonary embolism, cerebral embolism, and myocardial infarction. Thrombus aspiration involves directing a catheter to the site of the thrombus under negative pressure, drawing the thrombus directly into the catheter for removal.

[0003] The advantages of catheter-based thrombus aspiration are:

[0004] (1) Minimally invasive. Patients with high-risk embolism are in critical condition and often find it difficult to tolerate traditional open surgery. In contrast, interventional therapy involves catheter aspiration under local anesthesia, which is less invasive and allows for faster recovery.

[0005] (2) Rapid effectiveness.

[0006] However, a common disadvantage of current thrombus aspiration devices is that hardened and fibrotic thrombi cannot be effectively extracted with relatively low negative pressure, but if the negative pressure is increased, too much blood will be extracted, causing clinical problems due to excessive blood loss.

[0007] Patent document CN115844488A discloses a thrombus aspiration pump with automatic target flow rate adjustment and its use method, comprising a suction pump main unit, a fluid reservoir, a connecting pipe, and a suction catheter; the suction pump main unit is connected to the fluid reservoir; the fluid reservoir is connected to one end of the connecting pipe; a proportional pinch valve and a pressure sensor are provided on the flow path between the fluid reservoir and the connecting pipe, and the first and second pressure measuring ports of the pressure sensor are located on the flow path between the fluid reservoir and the connecting pipe, and the other end of the connecting pipe is connected to the suction catheter. However, this patent cannot completely solve the existing technical problems, nor can it meet the requirements of the present invention.

[0008] Summary of the Invention

[0009] In view of the defects in the prior art, the purpose of the present invention is to provide an intermittent thrombus aspiration pump system.

[0010] The intermittent thrombus aspiration pump system provided by the present invention comprises: a suction catheter, a flow resistor, a first pressure sensor, a second pressure sensor, a metering pump, a pinch valve, a collection container, a third pressure sensor, a negative pressure regulating valve and a negative pressure pump;

[0011] The suction catheter, the first pressure sensor, the flow resistor, the second pressure sensor, the pinch valve, the collection container, the third pressure sensor, the negative pressure regulating valve and the negative pressure pump are connected in sequence;

[0012] The two ends of the metering pump are respectively connected to the two ends of the pinch valve.

[0013] Preferably, the suction catheter is a catheter that enters the human body and performs thrombus aspiration.

[0014] Preferably, the flow resistance is between the first pressure sensor and the second pressure sensor, so that when blood flows, a pressure difference is generated between the first pressure sensor and the second pressure sensor, and this pressure difference is proportional to the blood flow rate, thereby determining the blood flow rate.

[0015] Preferably, the third pressure sensor is used to measure the negative pressure intensity in the collection container, and is used to determine whether the thrombus aspiration pump system has reached a preset target suction negative pressure;

[0016] The negative pressure regulating valve is used to adjust the negative pressure output by the negative pressure pump. The negative pressure pump is used to generate a negative pressure for suction and is a negative pressure source.

[0017] Preferably, the flow resistance is a straight pipe or a disc-shaped bend pipe.

[0018] Preferably, the metering pump generates a liquid flow direction when in operation, discharging the liquid on one side of the pinch valve into the other side, thereby generating a greater pressure difference.

[0019] Preferably, when the thrombus aspiration pump system is aspirating, there is liquid from the suction catheter to the collection container, and intermittent aspiration is achieved by opening and closing the pinch valve; when the pinch valve is closed, the suction pipeline is cut off, and at this time there is liquid in the pipelines on both sides of the pinch valve; at this time the metering pump starts to work: the liquid downstream of the pinch valve is aspirated to the upstream of the pinch valve, the liquid upstream of the pinch valve increases, and the pressure also increases accordingly; the liquid downstream of the pinch valve decreases, and the pressure also decreases accordingly, achieving the purpose of increasing the pressure difference; the pressure downstream of the pinch valve is measured by the third pressure sensor, and the pressure upstream of the pinch valve is measured by the first pressure sensor. The pressure difference between the third pressure sensor and the first pressure sensor represents the size of the pressure difference. The greater the pressure difference, the more obvious the thrombus aspiration effect.

[0020] Preferably, the liquid downstream of the pinch valve is sucked into a collection container to reduce the pressure upstream of the pinch valve, or the liquid from an external pressure source is sucked upstream of the pinch valve to increase the pressure upstream of the pinch valve.

[0021] Preferably, the second pressure sensor is used to monitor the pressure upstream of the pinch valve, and when the pressure upstream of the pinch valve reaches a set limit, the metering pump is stopped;

[0022] When the metering pump stops working, the pinch valve is released and the suction pipeline passage is restored. At this time, the pressure is released instantly, achieving the purpose of aspirating stubborn thrombus.

[0023] Preferably, a flow sensor or other sensors and devices that directly or indirectly measure blood flow velocity are used instead of the pressure sensor.

[0024] Compared with the prior art, the present invention has the following beneficial effects:

[0025] (1) The present invention can establish an on-off mechanism on the suction catheter pathway, and control the on-off mechanism to open and close at a certain frequency, thereby forming intermittent suction. When the suction pathway is disconnected, a diaphragm pump or a metering pump is used to quickly draw the liquid from one end of the collection container to the other end of the patient, thereby reducing the pressure near the collection container and increasing the pressure near the patient, thereby forming a certain pressure difference. When the pressure difference reaches a certain amount, the negative pressure switch is closed, and the pressure difference formed at this time can quickly and effectively draw out stubborn thrombi.

[0026] (2) The present invention can actively increase the pressure difference without increasing the negative pressure output by the negative pressure pump, thereby achieving the purpose of instantaneous thrombus attraction. If the negative pressure output by the negative pressure pump is increased, it may cause excessive blood loss in the patient. The actively formed pressure difference only works for an instant and does not increase the patient's blood loss, but it can effectively attract thrombus. This method can be combined with the intermittent suction frequency to achieve the purpose of high-frequency, high-pressure difference intermittent suction. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Other features, objects and advantages of the present invention will become more apparent upon reading the detailed description of non-limiting embodiments with reference to the following drawings:

[0028] FIG1 is a schematic structural diagram of an intermittent thrombus aspiration pump system according to the present invention;

[0029] FIG2 is a schematic structural diagram of the intermittent thrombus aspiration pump system of the present invention;

[0030] FIG3 is a schematic structural diagram of the intermittent thrombus aspiration pump system of the present invention. DETAILED DESCRIPTION

[0031] The present invention will be described in detail below with reference to specific embodiments. The following examples will help those skilled in the art to further understand the present invention, but are not intended to limit the present invention in any form. It should be noted that, for those skilled in the art, several changes and improvements can be made without departing from the scope of the present invention. These all fall within the scope of protection of the present invention.

[0032] Example

[0033] As shown in Figures 1 to 3, the present invention provides an intermittent thrombus aspiration pump system, comprising: a suction catheter 1, a flow resistor 2, a first pressure sensor 4, a second pressure sensor 3, a metering pump 5, a pinch valve 6, a collection container 7, a third pressure sensor 8, a negative pressure regulating valve 9, and a negative pressure pump 10;

[0034] The flow resistance 2 is between the first pressure sensor 4 and the second pressure sensor 3, so that when blood flows, a pressure difference is generated between the first pressure sensor 4 and the second pressure sensor 3. This pressure difference is proportional to the blood flow rate, thereby determining the blood flow rate.

[0035] The third pressure sensor 8 is used to measure the negative pressure intensity in the collection tank, and is used to determine whether the system has reached the target suction negative pressure.

[0036] The negative pressure regulating valve 9 is used to adjust the negative pressure output by the negative pressure pump.

[0037] The negative pressure pump 10 is used to generate a negative pressure for suction and is a negative pressure source.

[0038] The suction catheter 1 is a catheter that enters the human body and performs thrombus aspiration, and is a medical device.

[0039] The flow resistance 2 can be a straight pipe, or a coiled bend pipe, or other shapes that can generate a pressure difference.

[0040] The metering pump 5 can generate a liquid flow when working, the purpose of which is to discharge the liquid on one side of the pinch valve 6 to the other side, thereby generating a larger pressure difference.

[0041] Working principle:

[0042] When the device is suctioning, there will be liquid from the suction catheter 1 to the collection container 7, and intermittent suction is achieved by opening and closing the pinch valve 6;

[0043] When the pinch valve 6 is closed, the suction pipe 1 is cut off. At this time, liquid is present in the pipes on both sides of the pinch valve 6.

[0044] At this point, metering pump 5 begins operation: liquid downstream of pinch valve 6 is drawn upstream of pinch valve 6. As the amount of liquid upstream of pinch valve 6 increases, the pressure also increases accordingly. As the amount of liquid downstream of pinch valve 6 decreases, the pressure also decreases accordingly, thereby increasing the pressure differential. Third pressure sensor 8 measures the pressure downstream of pinch valve 6, while first pressure sensor 4 measures the pressure upstream of pinch valve 6. The pressure difference between third pressure sensor 8 and first pressure sensor 4 represents the magnitude of the resulting pressure differential. The greater the pressure differential, the more effective the thrombus aspiration. In practice, the pressure differential can often reach two atmospheres, while conventional aspiration is limited to a maximum negative pressure of one atmosphere. Therefore, aspirating liquid from both ends of pinch valve 6 can achieve a stronger aspiration effect. The present invention is not limited to aspirating liquid downstream of pinch valve 6 upstream of pinch valve 6. Liquid downstream of pinch valve 6 can also be aspirated into collection container 7 to reduce the pressure upstream of pinch valve 6, or liquid from an external pressure source can be aspirated upstream of pinch valve 6 to increase the pressure upstream of pinch valve 6.

[0045] The second pressure sensor 3 is used to determine the pressure limit upstream of the pinch valve 6. When the pressure upstream of the pinch valve 6 reaches the set limit, the metering pump 5 can be stopped to ensure that the pressure upstream of the pinch valve 6 is not too high.

[0046] When the metering pump 5 stops working, the pinch valve 6 is released and the passage of the suction pipe 1 is restored. At this time, the pressure formed in the previous step is released instantly, achieving the purpose of aspirating the stubborn thrombus.

[0047] Pressure sensors can also be used as flow sensors or other sensors or devices that directly or indirectly measure blood flow velocity.

[0048] In the description of this application, it should be understood that the terms "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0049] Those skilled in the art will appreciate that, in addition to implementing the system, device, and various modules provided by the present invention in purely computer-readable program code, it is entirely possible to implement the same program in the form of logic gates, switches, application-specific integrated circuits, programmable logic controllers, embedded microcontrollers, and the like by logically programming the method steps. Therefore, the system, device, and various modules provided by the present invention can be considered a hardware component, and the modules included therein for implementing various programs can also be considered structures within the hardware component; the modules for implementing various functions can also be considered both software programs for implementing the method and structures within the hardware component.

[0050] The above describes specific embodiments of the present invention. It should be understood that the present invention is not limited to the specific embodiments described above, and those skilled in the art may make various changes or modifications within the scope of the claims, which do not affect the essence of the present invention. The embodiments of this application and the features in the embodiments may be combined with each other in any manner unless there is a conflict.

Claims

1. An intermittent thrombus aspiration pump system, characterized in that: include: A suction catheter (1), a flow resistor (2), a first pressure sensor (4), a second pressure sensor (3), a metering pump (5), a pinch valve (6), a collection container (7), a third pressure sensor (8), a negative pressure regulating valve (9) and a negative pressure pump (10); The suction catheter (1), the first pressure sensor (4), the flow resistor (2), the second pressure sensor (3), the pinch valve (6), the collection container (7), the third pressure sensor (8), the negative pressure regulating valve (9) and the negative pressure pump (10) are connected in sequence; The two ends of the metering pump (5) are respectively connected to the two ends of the pinch valve (6).

2. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: The suction catheter (1) is a catheter that enters the human body and performs thrombus suction.

3. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: The flow resistance (2) is between the first pressure sensor (4) and the second pressure sensor (3), so that when blood flows, a pressure difference is generated between the first pressure sensor (4) and the second pressure sensor (3), and the pressure difference is proportional to the blood flow rate, thereby determining the blood flow rate.

4. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: The third pressure sensor (8) is used to measure the negative pressure intensity in the collection container (7) to determine whether the thrombus aspiration pump system has reached a preset target suction negative pressure; The negative pressure regulating valve (9) is used to adjust the negative pressure output by the negative pressure pump, and the negative pressure pump (10) is used to generate a negative pressure for suction and is a negative pressure source.

5. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: The flow resistance (2) is a straight pipe or a disc-shaped curved pipe.

6. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: The metering pump (5) generates a liquid flow when working, discharging the liquid on one side of the pinch valve (6) into the other side, thereby generating a larger pressure difference.

7. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: When the thrombus aspiration pump system is aspirating, liquid exists from the suction catheter (1) to the collection container (7), and intermittent aspiration is achieved by opening and closing the pinch valve (6); when the pinch valve (6) is closed, the suction pipeline (1) is cut off, and liquid exists in the pipelines on both sides of the pinch valve (6); at this time, the quantitative pump (5) starts to work: the liquid downstream of the pinch valve (6) is aspirated to the upstream of the pinch valve (6), the liquid upstream of the pinch valve (6) increases, and the pressure also increases accordingly; the liquid downstream of the pinch valve (6) decreases, and the pressure also decreases accordingly, so as to achieve the purpose of increasing the pressure difference; the pressure downstream of the pinch valve (6) is measured by the third pressure sensor (8), and the pressure upstream of the pinch valve (6) is measured by the first pressure sensor (4). The pressure difference between the third pressure sensor (8) and the first pressure sensor (4) represents the magnitude of the pressure difference. The greater the pressure difference, the more obvious the thrombus aspiration effect.

8. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: The liquid downstream of the pinch valve (6) is sucked into the collecting container (7) to reduce the pressure upstream of the pinch valve (6), or the liquid from the external pressure source is sucked upstream of the pinch valve (6) to increase the pressure upstream of the pinch valve (6).

9. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: The second pressure sensor (3) is used to monitor the pressure upstream of the pinch valve (6), and when the pressure upstream of the pinch valve (6) reaches a set limit, the metering pump (5) is stopped; When the metering pump (5) stops working, the clamping valve (6) is released, and the passage of the suction pipeline (1) is restored. At this time, the pressure is released instantly, thereby achieving the purpose of aspirating stubborn thrombus.

10. The intermittent thrombus aspiration pump system according to claim 1, characterized in that: A flow sensor or other sensors and devices that directly or indirectly measure blood flow velocity are used instead of a pressure sensor.

Images