Capacity-adjustable cell culture bag

Abstract

The present invention relates to a capacity-adjustable cell culture bag. Specifically, the capacity-adjustable cell culture bag comprises: a body including a front sheet provided with multiple wings spaced apart in the vertical direction on the outer surface thereof, and a rear sheet of which an edge is coupled to the front sheet to form a receiving space between the front sheet and the rear sheet; an injection tube provided at the lower end of the body to supply a culture medium to the receiving space; and a sealing clamp which winds the body from the upper end thereof toward the rear sheet and then presses a wing in surface-contact with the rear sheet among the multiple wings together with a part of the body that is not wound, thereby having the effect of preventing the body from loosening, and thus maintaining the volume of the adjusted receiving space inside the body.

Description

Adjustable capacity cell culture bag

[0001] The present invention relates to a cell culture bag, and more particularly, to a cell culture bag with adjustable capacity, which can expand the internal volume to allow the addition of a culture medium.

[0002] Cell culture bags are used in all culture industries for culturing animal cells, microorganisms, or viruses (hereinafter simply referred to as “cells, etc.”). They are made of a flexible film or sheet and filled with a culture solution containing cells, etc. and the nutrients they require.

[0003] When cells, etc. are cultured inside a cell culture bag and the cells grow, more culture medium is required. Therefore, the contents of the cells and culture medium mixed together must be transferred to another culture bag with a larger internal volume.

[0004] However, there is a possibility that cells and other culture media may be lost or contaminated during the process of transferring them to another culture bag.

[0005] The present invention has been devised to solve the problems of the above-mentioned prior art, and its purpose is to provide a cell culture bag with an adjustable capacity, which is configured to have an expandable internal volume so that not only can a culture medium be added therein, but also can maintain the expanded state.

[0006] In order to solve the above-described problem, the cell culture bag of the present invention is configured to include a main body comprising a front sheet having a plurality of wings spaced apart in the vertical direction on an outer surface thereof, and a rear sheet having an edge joined to the front sheet to form a receiving space therebetween; an injection tube provided at a lower end of the main body to supply a culture medium to the receiving space; and a sealing clamp for winding the main body from the top toward the rear sheet and then pressurizing a wing among the plurality of wings that is in contact with the rear sheet together with a portion of the main body that is not wound.

[0007] Meanwhile, the present invention comprises a main body comprising a front sheet and a rear sheet having an edge joined to the front sheet to form a receiving space therebetween; and an injection tube provided at the lower end of the main body to supply a culture medium to the receiving space; wherein, on the outer surface of the front sheet, a first wing having a first attachment surface provided on the lower surface is provided spaced apart in the vertical direction, and on the outer surface of the rear sheet, a second wing having a second attachment surface provided on the upper surface, which is in close contact with the first attachment surface, is provided spaced apart in the vertical direction, so that after the main body is wound downward from the top by a certain length, the second attachment surface is in close contact with the first attachment surface.

[0008] Here, the first and second wings are formed so that the one provided on the lower side has a longer vertical length than the one provided on the upper side.

[0009] And, the main body is provided with a rolling pin having a certain rigidity at the top.

[0010] Additionally, a number indicating the storage space capacity of the main body is printed on the rear sheet.

[0011] The cell culture bag of the present invention configured as described above has the advantage of preventing the body from unraveling by having wings that come into contact with the back sheet by means of a sealing clamp pressed against the unwound portion of the body, thereby maintaining the volume of the regulated storage space inside the body.

[0012] In addition, since the first attachment surface of the first wing and the second attachment surface of the second wing are in close contact with each other and the roundly wound main body is trapped by the first wing and the second wing, the wound main body can be prevented from unraveling, so there is an advantage in that the adjusted accommodation space volume of the main body can be maintained.

[0013] Figures 1 to 4 are drawings showing one embodiment of a cell culture bag with adjustable capacity according to the present invention.

[0014] Figures 5 and 6 are drawings showing another embodiment of a capacity-adjustable cell culture bag according to the present invention.

[0015] Hereinafter, an embodiment of a cell culture bag with adjustable capacity according to the present invention will be described in detail with reference to the attached drawings 1 to 4.

[0016] FIGS. 1 to 4 are diagrams showing one embodiment of a cell culture bag with adjustable capacity according to the present invention, and FIGS. 5 and 6 are diagrams showing another embodiment of a cell culture bag with adjustable capacity according to the present invention.

[0017] The cell culture medium with adjustable capacity according to the present invention illustrated in FIGS. 1 to 4 comprises a main body (100), an injection tube (200) provided at the lower end of the main body (100), and a sealing clamp (300) coupled to the main body (100) to maintain the capacity of the main body (100).

[0018] The above body (100) is composed of a front sheet (110) and a rear sheet (120) whose edges are tightly bonded to the edges of the front sheet (110) by a method such as fusion, thereby forming a receiving space between the front sheet (110). The receiving space formed between the front sheet (110) and the rear sheet (120) is filled with a culture medium containing cells, microorganisms, viruses, and other substances and nutrients required by the cells, microorganisms, or viruses.

[0019] In addition, the front sheet (110) is provided with a number of wings (111) spaced apart in the vertical direction on the outer surface.

[0020] The above wing (111), like the front sheet (110) and the rear sheet (120), is made of a flexible film or sheet, and can be freely bent or folded. One end of the wing (111) is a fixed end connected to the outer surface of the front sheet (110), and the other end is a free end that is not connected to anything.

[0021] Meanwhile, a rolling pin (130) having a certain rigidity is provided at the top of the main body (100).

[0022] The above rolling pin (130) is made of plastic or steel material so that it does not bend or fold, thereby making the winding process easier when the main body (100) is pressed from the top to the bottom around the rolling pin (130).

[0023] In addition, a numerical value indicating the capacity of the storage space is printed on the outer surface of the front sheet (110) and the outer surface of the rear sheet (120). Therefore, it is possible to intuitively determine the amount of culture medium stored inside the main body (100).

[0024] The above injection tube (200) is provided at the bottom of the main body (100) and supplies a culture medium to the receiving space. That is, the upper portion of the injection tube (200) is inserted between the front sheet (110) and the rear sheet (120) and is connected to the receiving space between the front sheet (110) and the rear sheet (120). Therefore, a culture medium, etc. can be supplied to the receiving space through the injection tube (200).

[0025] The above sealing clamp (300) is used to maintain the adjusted state when the capacity of the accommodation space is adjusted by pressurizing and sealing the wings (111) and the main body (100) together. To explain in more detail, the main body (100) is rolled up starting from the top around the rolling pin (130) toward the rear sheet (120), and then, among the plurality of wings (111), the wings that come into contact with the rear sheet (120) are pressed and sealed together with the unrolled portion of the main body (100) by the sealing clamp (300). In this way, the main body (100) rolled up around the rolling pin (130) is trapped between the wings (111) and the rear sheet (120), thereby preventing the rolled main body (100) from unraveling. Therefore, the adjusted volume of the accommodation space can be maintained.

[0026] Meanwhile, the present invention can also be configured as shown in FIGS. 5 and 6.

[0027] Figures 5 and 6 are diagrams showing another embodiment of a cell culture bag with adjustable capacity according to the present invention.

[0028]

[0029] *The capacity-adjustable cell culture bag according to the present invention illustrated in FIGS. 5 and 6 is configured to include a main body (100) and an injection tube (200) provided at the bottom of the main body (100).

[0030] The above body (100) is composed of a front sheet (110) and a rear sheet (120) whose edges are tightly bonded to the edges of the front sheet (110) by a method such as fusion, thereby forming a receiving space between the front sheet (110).

[0031] The above front sheet (110) is provided with a plurality of first wings (112) spaced apart in the vertical direction on the outer surface, and the first wings (112) are provided with a first attachment surface (112a) on the lower surface.

[0032] The above rear sheet (120) is provided with a plurality of second wings (121) spaced apart in the vertical direction on the outer surface, and the second wings (121) are provided with a second attachment surface (121a) on the upper surface.

[0033] The first attachment surface (112a) of the first wing (112) and the second attachment surface (121a) of the second wing (121) are parts that adhere to each other and can be formed of things such as Velcro tape. That is, if the first attachment surface (112a) is made of a female Velcro tape, the second attachment surface (121a) is made of a male Velcro tape so that the first attachment surface (112a) and the second attachment surface (121a) can be firmly attached to each other.

[0034] When the main body (100) equipped with the first wing (112) and the second wing (121) is wound from the top to the bottom by a certain length and the second attachment surface (121a) is pressed against the first attachment surface (112a), the wound main body (100) is prevented from unraveling by being trapped between the first wing (112) and the second wing (121). Accordingly, the volume of the adjusted accommodation space can be maintained.

[0035] Here, the first wing (112) and the second wing (121) are formed so that the one provided on the lower side is longer in the vertical direction than the one provided on the upper side. That is, among the plurality of first wings (112) and second wings (121) provided spaced apart from each other in the vertical direction, the first wing (112) and the second wing (121) located at the lowest side are the longest, and the first wing (112) and the second wing (121) located at the highest side are the shortest.

[0036] The reason for configuring it this way is to cope with the fact that the diameter of the main body (100) becomes larger as the main body (100) is rolled from the top to the bottom. In other words, the first wing (112) and the second wing (121) located at the lowest side must surround the main body (100) that is wound the most and has a larger diameter, and the first wing (112) and the second wing (121) located at the highest side must surround the main body (100) that is wound the least and has a smaller diameter, and therefore their lengths are different.

[0037] Meanwhile, a rolling pin (130) having a certain rigidity is provided at the top of the main body (100). The rolling pin (130) is made of plastic or steel so as not to bend or bend, thereby making the main body (100) easier to wind from the top to the bottom when winding it around the rolling pin (130).

[0038] In addition, a numerical value indicating the capacity of the storage space is printed on the outer surface of the front sheet (110) and the outer surface of the rear sheet (120). Therefore, it is possible to intuitively determine the amount of culture medium stored inside the main body (100).

[0039] The above injection tube (200) is provided at the bottom of the main body (100) and supplies a culture medium to the receiving space. That is, the upper portion of the injection tube (200) is inserted between the front sheet (110) and the rear sheet (120) and is connected to the receiving space between the front sheet (110) and the rear sheet (120). Therefore, a culture medium, etc. can be supplied to the receiving space through the injection tube (200).

Claims

1. A main body (100) comprising a front sheet (110) and a back sheet (120) having an edge joined to the front sheet (110) to form a receiving space between the front sheet (110) and the back sheet (120) having a numerical value printed thereon indicating the capacity of the receiving space, and having a rolling pin (130) having a certain rigidity provided at the top; Including an injection tube (200) provided at the bottom of the main body (100) and supplying a culture medium to the receiving space; The outer surface of the front sheet (110) includes a first wing (112) having a first attachment surface (112a) provided on the lower surface and spaced apart in the vertical direction, and the outer surface of the rear sheet (120) includes a second wing (121) having a second attachment surface (121a) provided on the upper surface and spaced apart in the vertical direction, which is in close contact with the first attachment surface (112a), so that the main body (100) is wound from the upper side to the lower side by a predetermined length and then the second attachment surface (121a) is brought into close contact with the first attachment surface (112a), thereby forming a main body (100) that was wound around the rolling pin (130) into a form in which it is trapped between the first wing (112) and the second wing (121). A capacity-adjustable cell culture bag, characterized in that the first wing (112) and the second wing (121) provided on the lower side have a longer vertical length than the wing provided on the upper side.

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