Collimation apparatus, neutron capture therapy system, and recognition method for collimation apparatus
By incorporating an identification device into the collimator of the neutron capture therapy system, rapid identification and matching of the collimator are achieved, solving the problem of inability to identify the collimator after replacement and improving system safety and operator protection.
Patent Information
- Application Number
- PCT/CN2025/091641
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-04-23
- Filing Date
- 2025-04-28
- Publication Date
- 2026-01-22
AI Technical Summary
Existing neutron capture therapy systems cannot identify or provide feedback on whether they are correctly matched to the current treatment plan after the collimator is replaced, posing a safety hazard.
A collimation device is designed, including a base and a collimation part. By setting identification devices on the base and the collimation part, and utilizing the matching response of the first identification part and the second identification part, it is ensured that the collimation part can quickly identify whether its model or parameters meet the current treatment plan during installation.
The installation process of the collimator is simplified, the time operators spend at the beam shaping assembly is reduced, radiation health risks are lowered, and identification accuracy and equipment safety are improved.
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Figure CN2025091641_22012026_PF_FP_ABST
Abstract
Description
Methods for identifying collimating devices, neutron capture therapy systems, and collimating devices Technical Field
[0001] This invention relates to the field of neutron capture therapy, and specifically provides a collimation device, a neutron capture therapy system, and a method for identifying the collimation device. Background Technology
[0002] The description in this section provides only background information relevant to the disclosure of this application and does not constitute prior art.
[0003] With the development of atomic science, neutron capture therapy (e.g., boron neutron capture therapy (BNCT)) has emerged as a novel cancer treatment method due to its precise targeting properties and high relative biological effects. The treatment process involves: first, injecting a boron-containing compound with specific adsorption capacity for tumors into the patient's body; then, waiting for the tumor to... 10 After the boron atoms are aggregated, the tumor is irradiated with an ultrathermal / thermal neutron beam, and the neutrons are absorbed by the tumor. 10 After B is captured, a nuclear reaction occurs, releasing alpha particles and... 7 Li particles cause significant damage to cells, and their total range is within a single cell, thus enabling them to locally kill tumor cells without destroying normal cells.
[0004] A neutron capture therapy system may include an accelerator and a beam shaping system, wherein the beam shaping system may include a beam shaper and a target disposed within the beam shaper. When the accelerator accelerates a beam of charged particles to a level sufficient to overcome the Coulomb repulsion of the atomic nuclei in the target, the charged particle beam undergoes a nuclear reaction with the target to produce neutrons, which are then adapted for therapy after being modulated by the energy spectrum of the beam shaper.
[0005] A collimator for beam collimation is usually placed between the accelerator and the patient. The collimator has a beam outlet of a preset size in the center. Neutrons emitted from the beam shaper pass through the beam outlet of the collimator, thereby forming a neutron beam for treatment within a preset irradiation range.
[0006] During the treatment planning process before irradiation, factors such as the patient's age, treatment site, and irradiation dose vary, necessitating the replacement of collimators of different sizes and / or shapes to ensure appropriate irradiation intensity. However, existing collimators cannot identify or provide feedback on whether they correctly match the current treatment plan after replacement, thus posing certain safety risks. Summary of the Invention
[0007] Based on the aforementioned deficiencies in the prior art, the neutron capture therapy system in this application is used to solve the problem of the collimator not being recognized after replacement.
[0008] This application discloses a collimation device, which includes a base and a collimation part, and the base and the collimation part are detachably connected. The collimation device also includes an identification device for identifying the collimation part. The identification device includes a first identification part disposed on the base and a second identification part correspondingly disposed on the collimation part. The second identification part can match and respond to at least a portion of the first identification part.
[0009] This invention features a detachable connection between the base and the collimator, allowing for the installation of different collimators and bases according to the patient's specific condition, ensuring the patient receives appropriate irradiation intensity. The first and second identification parts are respectively located on the base and collimator, enabling immediate identification of the current collimator each time it is installed on the base. This simplifies the installation process, reduces the time operators spend confirming whether the collimator conforms to the current treatment plan, and consequently reduces the time operators spend at the beam exit of the beam shaping assembly, lowering the health risks of radiation exposure for operators. After replacing the collimator, the matching between the first and second identification parts allows for the identification of the new collimator's model or parameters, ensuring its suitability for the current patient's treatment plan and guaranteeing equipment safety.
[0010] Furthermore, the first identification unit includes a first identification unit, and the second identification unit includes a second identification unit, wherein the second identification unit can match and respond to at least a portion of the first identification unit. Through the above configuration, based on the matching relationship between the first and second identification units, the model or parameters of the replaced collimator can be identified, thereby determining whether the replaced collimator is suitable for the current patient's treatment plan.
[0011] Furthermore, different collimators are equipped with different second recognition units. Through the above configuration, when different collimators are connected to the base, the second recognition units corresponding to the collimators are also different. Different matching situations between the second recognition unit and the first recognition unit correspond to different models of collimators, thereby effectively improving the accuracy and efficiency of recognizing the collimators.
[0012] Furthermore, multiple first identification units are arranged at intervals or at intervals along the circumferential direction. Through the above configuration, the interval arrangement of the first identification units allows for more accurate positioning when corresponding first and second identification units are matched, preventing identification errors from affecting the patient's treatment outcome. The circumferential arrangement allows for more efficient use of the space within the collimation device.
[0013] Furthermore, the first identification unit includes a first universal unit, and the second identification unit includes a second universal unit. The first universal unit and the second universal unit are correspondingly arranged, wherein the second universal units on different collimation units are identical. The arrangement of the first universal unit and the second universal unit provides a positioning basis for the docking of the first identification unit and the second identification unit. Moreover, only when the first universal unit and the second universal unit are accurately docked can the matching status of the first identification unit and the second identification unit be used as the basis for determining the collimation unit, further ensuring the patient's treatment effect and eliminating the safety hazard of the patient receiving irradiation intensity that does not conform to their treatment plan.
[0014] Furthermore, the second identification unit may come into contact with at least a portion of the first identification unit. Through the above configuration, partial structures between the first and second identification units can contact each other, allowing different matching conditions between the first and second identification units to be determined by means of circuit conduction.
[0015] Furthermore, the collimation device also includes an anti-collision device, which is mounted on the base and outputs a warning signal when the collimation head is subjected to force. With this configuration, when the collimation head comes into contact with the skin or bone near the patient, the anti-collision device issues a warning signal, allowing the operator to make appropriate adjustments to ensure the collimation head maintains a suitable distance from the patient, thereby guaranteeing a reasonable source-skin distance and irradiation intensity to ensure the patient's treatment effectiveness.
[0016] Furthermore, the anti-collision device includes a sensing device that outputs a pressure signal when the collimator is subjected to force. The pressure signal has a fast response time. Through the above configuration, the anti-collision device can promptly prompt the operator to adjust the collimator, ensuring that the collimator always maintains a suitable distance from the patient, thereby guaranteeing a reasonable source-skin distance and irradiation intensity, and ultimately ensuring that the actual neutron dose received by the patient meets the requirements of the treatment plan.
[0017] Furthermore, the base has a first side facing the collimator and a second side facing away from the collimator, with the sensing device disposed on the second side of the base. Since the collimator needs to be frequently replaced according to the patient's treatment plan, this design avoids frequent friction on the sensing device, preventing inaccurate data acquisition, extending the lifespan of the collimator, and reducing the cost of equipment replacement.
[0018] Furthermore, the anti-collision device includes an alarm device that outputs a light signal when the collimating part is subjected to a force exceeding a preset range. Through these features, the light signal is less susceptible to interference than other signals and is extremely easy for the operator to perceive, allowing for rapid adjustment of the collimating device to ensure a reasonable source-skin distance and irradiation intensity, thereby guaranteeing the patient's treatment effectiveness.
[0019] Furthermore, the base has a first side facing the collimator and a second side facing away from the collimator. The sensing device is located on the second side of the base, and the alarm device is located on the first side of the base. With this configuration, the alarm information emitted by the alarm device will not be obstructed by the base, making it easier for the operator to perceive. This allows the operator to quickly adjust the distance between the patient and the collimator to ensure treatment effectiveness and eliminate the safety hazard of the patient receiving irradiation intensities inconsistent with their treatment plan.
[0020] Furthermore, the base is also provided with a signal output section for signal output, which is electrically connected to the identification device.
[0021] Furthermore, the base includes a stop unit and an annular unit located radially outside the stop unit. The stop unit and the annular unit form a groove, within which the collimator can be fitted. Through this arrangement, the radial movement and movement toward the stop unit of the collimator positioned in the groove are restricted, enabling precise positioning of the collimator once it is installed in the groove. This improves the irradiation accuracy of the neutron beam, ensuring beam quality and therapeutic efficacy.
[0022] Furthermore, the stop unit has a first side facing the collimator and a second side facing away from the collimator, with the first identification part disposed on the first side of the stop unit. Through this arrangement, the first identification part can directly interface with the second identification part on the collimator, eliminating the need for additional wiring within the collimator, thus simplifying the internal structure of the collimator, streamlining the installation process for operators, and reducing the health risks of radiation exposure for personnel during replacement.
[0023] Furthermore, it also includes a locking mechanism for fixing the collimator to the base. With the locking mechanism, the collimator can be stably installed on the base, ensuring the normal operation of the identification device, anti-collision device, and other devices.
[0024] To address the problem of existing neutron capture therapy systems failing to recognize replaced collimators, this application also discloses a neutron capture therapy system. The neutron capture therapy system includes a collimating device comprising a base and at least one collimating section, detachably connected to the base. The collimating device also includes an identification device for identifying different collimating sections. The identification device includes a first identification section disposed on the base and a corresponding second identification section disposed on the collimating section, the second identification section being capable of matching and responding to at least a portion of the first identification section. By configuring the collimating device and detachably connecting the base and collimating section, different collimating sections and bases can be installed together according to the patient's specific condition, ensuring the patient receives an appropriate irradiation intensity. By placing the first and second identification units on the base and collimator respectively, the collimator can be identified immediately each time it is installed on the base. This simplifies the installation process, reduces the time operators spend confirming whether the collimator matches the current treatment plan, and consequently reduces the time operators spend at the beam exit of the beam shaping assembly, thus lowering the health risks of radiation exposure. After replacing the collimator, the model, characteristics, or parameters of the replaced collimator can be identified based on the matching between the first and second identification units, facilitating the determination of whether the replaced collimator matches the current patient's treatment plan and ensuring the safety of the neutron capture therapy system.
[0025] Furthermore, the first identification section includes a first identification unit, and the second identification section includes a second identification unit, wherein the second identification unit can match and respond with at least a portion of the first identification unit. With the above configuration, after replacing the collimator, the model, characteristics, or parameters of the replaced collimator can be identified based on the matching relationship between the first and second identification units. This facilitates determining whether the replaced collimator matches the current patient's treatment plan, ensuring the safety of the neutron capture therapy system.
[0026] Furthermore, different collimators are equipped with different second identification units. Through the above configuration, when different collimators are connected to the base, the second identification units corresponding to the collimators are also different. Different matching situations between the second identification unit and the first identification unit correspond to different models of collimators, which facilitates quick and accurate identification of the current collimator.
[0027] Furthermore, multiple first identification units are arranged at intervals or at intervals along the circumferential direction. Through the above configuration, the interval arrangement of the first identification units allows for more accurate positioning when corresponding first and second identification units are matched, preventing identification errors from affecting the patient's treatment outcome. The circumferential arrangement allows for more efficient use of the space within the collimation device of the neutron capture therapy system.
[0028] Furthermore, the first identification unit includes a first universal unit, and the second identification unit includes a second universal unit. The first universal unit and the second universal unit are correspondingly arranged, wherein the second universal units on different collimation units are identical. The arrangement of the first universal unit and the second universal unit provides a positioning basis for the docking of the first identification unit and the second identification unit. Moreover, only when the first universal unit and the second universal unit are accurately docked can the matching status of the first identification unit and the second identification unit be used as the basis for determining the collimation unit, further ensuring the patient's treatment effect and eliminating the safety hazard of the patient receiving irradiation intensity that does not conform to their treatment plan.
[0029] Furthermore, the second identification unit may come into contact with at least a portion of the first identification unit. Through the above configuration, partial structures between the first and second identification units can contact each other, facilitating the determination of different matching conditions between the first and second identification units using a circuit-connected approach.
[0030] To address the problem that existing neutron capture therapy systems cannot recognize replaced collimators, this application also discloses a method for recognizing collimators. The collimator includes a base and a collimating section; the collimator also includes an identification device, which includes a first identification section disposed on the base and a second identification section correspondingly disposed on the collimating section. The second identification section can match at least a portion of the first identification section. The identification method includes the following steps: setting the collimating section on the base, such that the second identification section matches a portion of the first identification section; in response to the matching of the second identification section with the portion of the first identification section, the identification device identifies the collimating section; determining whether the identified collimating section matches the treatment plan; wherein the identification device can identify at least two different collimating sections. Through the above configuration, after the collimating section is set on the base, the first identification section matches the second identification section, facilitating the identification of the collimating section. This simplifies the installation process of the collimating section, reduces the time required for operators to confirm whether the collimating section conforms to the current treatment plan, and consequently reduces the time operators spend at the beam exit of the beam shaping assembly, thus reducing the health risks of radiation exposure for operators. After replacing the collimator, it is possible to determine whether the currently identified collimator is in line with the current patient's treatment plan, thus ensuring the safety of the collimator.
[0031] Furthermore, the identification device includes a general unit and an identification unit. The step "identifying the collimation section by the identification device" includes: when both the general unit and the identification unit simultaneously meet preset conditions, identifying different collimations through the identification unit. Through the above configuration, the setting of the first general unit and the second general unit provides a positioning basis for the docking of the first identification unit and the second identification unit. Moreover, only when the first general unit and the second general unit are accurately docked can the matching status of the first identification unit and the second identification unit serve as the basis for determining the collimation section, further ensuring the patient's treatment effect and eliminating the safety hazard of the patient receiving irradiation intensity that does not conform to their treatment plan. Attached Figure Description
[0032] The preferred embodiments of the present invention are described below with reference to the accompanying drawings, in which:
[0033] Figure 1 is a schematic diagram of an embodiment of the collimation device of the present invention;
[0034] Figure 2 is a front structural schematic diagram of an embodiment of the base of the collimation device of the present invention;
[0035] Figure 3 is a schematic diagram of the rear structure of an embodiment of the base of the collimation device of the present invention;
[0036] Figure 4 is a partial schematic diagram at point A of an embodiment of the base of the collimation device of the present invention shown in Figure 2;
[0037] Figure 5 is a partial schematic diagram of the collimation section of the collimation device of the present invention;
[0038] Figure 6 is a partial schematic diagram at point B of an embodiment of the base of the collimation device of the present invention shown in Figure 3;
[0039] Figure 7 is a structural schematic diagram of an embodiment of the neutron capture therapy system of the present invention;
[0040] Figure 8 is a front view of an embodiment of the neutron capture therapy system of the present invention;
[0041] Figure 9 is a flowchart illustrating the identification method of the collimation device of the present invention.
[0042] List of reference numerals: 1. Neutron capture therapy system; 100. Collimation device; 10. Base; 11. Stop unit; 12. Ring unit; 121. Inner wall; 122. Outer wall; 13. First side; 14. Second side; 15. Groove; 20. Collimation part; 21. Body; 211. Frustum-shaped component; 2111. Platform; 2112. Beam exit; 212. Connecting plate; 30. Identification device; 31. First identification part; 311. First identification unit; 312. First universal unit; 32. Second identification part; 321. Second identification unit; 322. Second universal unit; 40. Sensing device; 50. Signal output part; 60. Locking mechanism; 700. Beam shaping body; 71. Signal receiving part; 800. Accelerator; 900. Neutron generating part. Detailed Implementation
[0043] Preferred embodiments of the present invention will now be described with reference to the accompanying drawings. Those skilled in the art should understand that these embodiments are merely illustrative of the technical principles of the present invention and are not intended to limit the scope of protection of the present invention.
[0044] It should be noted that in the description of this invention, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.
[0045] Furthermore, it should be noted that, in the description of this invention, unless otherwise explicitly specified and limited, the terms "set" and "connection" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection, an indirect connection through an intermediate medium, or a connection within two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.
[0046] Neutron capture therapy has seen increasing application as an effective cancer treatment method in recent years, with boron neutron capture therapy being the most common. Neutrons for boron neutron capture therapy can be supplied by nuclear reactors or accelerators. This application's embodiments use accelerator-based boron neutron capture therapy as an example. The basic components of accelerator-based boron neutron capture therapy typically include an accelerator for accelerating charged particles (such as protons, deuterons, etc.) and a neutron capture therapy system. The neutron capture therapy system includes a target material, a thermal removal system, and a beam shaper. The accelerated charged particles interact with the target material to produce neutrons. A suitable nuclear reaction is selected based on the required neutron yield and energy, the available energy and current of the accelerated charged particles, and the physicochemical properties of the target material. Commonly discussed nuclear reactions include... 7 Li(p,n) 7 Be and 9 Be(p,n) 9B. Both of these reactions are endothermic. The energy thresholds for the two nuclear reactions are 1.881 MeV and 2.055 MeV, respectively. Since the ideal neutron source for boron neutron capture therapy is hyperthermal neutrons at the keV energy level, theoretically, if protons with energies only slightly higher than the threshold are used to bombard a lithium metal target, relatively low-energy neutrons can be produced, which can be used clinically without much slowing treatment. However, the interaction cross-section between lithium metal (Li) and beryllium metal (Be) targets and protons at the threshold energy is not high. In order to generate a sufficiently large neutron flux, higher-energy protons are usually selected to initiate the nuclear reaction.
[0047] Ideally, a target material should possess characteristics such as high neutron yield, neutron energy distribution close to the hyperthermic neutron energy region (described in detail below), minimal strong penetration radiation, safety, low cost, ease of operation, and high temperature resistance. However, in reality, it is impossible to find a nuclear reaction that meets all these requirements. In the embodiments of this application, a target material made of lithium metal is used. However, as those skilled in the art will know, the target material can also be made of other metallic materials besides those discussed above.
[0048] The requirements for a thermal removal system vary depending on the nuclear reaction selected, such as 7 Li(p,n) 7 Due to the difference in melting point and thermal conductivity between the metal target material (lithium metal), the requirements for the heat removal system are relatively high. 9 Be(p,n) 9 B is high. In the embodiments of this application, the following are used: 7 Li(p,n) 7 Nuclear reactions of Be.
[0049] Regardless of whether the neutron source for boron neutron capture therapy originates from the nuclear reaction between charged particles and the target material in a nuclear reactor or accelerator, the resulting radiation field is a mixed field, meaning the beam contains neutrons and photons ranging from low to high energy. For boron neutron capture therapy of deep tumors, the higher the content of radiation other than hyperthermic neutrons, the greater the proportion of non-selective dose deposition in normal tissues. Therefore, these radiations that cause unnecessary doses should be minimized. In addition to air beam quality factors, to better understand the dose distribution caused by neutrons in the human body, the embodiments of this application use a human head tissue prosthesis for dose calculation, and the prosthesis beam quality factor is used as a design reference for the neutron beam, which will be described in detail below.
[0050] The International Atomic Energy Agency (IAEA) has issued five recommendations regarding air beam quality factors for neutron sources used in clinical boron neutron capture therapy. These recommendations can be used to compare the advantages and disadvantages of different neutron sources and serve as a reference for selecting neutron generation pathways and designing beam shapers. The five recommendations are as follows:
[0051] Epithermal neutron flux > 1 x 10⁻⁶ 9 n / cm 2 s
[0052] Fast neutron contamination < 2 x 10⁻⁶ -13 Gy-cm 2 / n
[0053] Photon contamination < 2 x 10⁻⁶ -13 Gy-cm 2 / n
[0054] The thermal to epithermal neutron flux ratio is <0.05; the epithermal neutron current to flux ratio is >0.7.
[0055] Note: The ultrathermal neutron energy ranges from 0.5 eV to 10 keV, the thermal neutron energy range is less than 0.5 eV, and the fast neutron energy range is greater than 10 keV.
[0056] 1. Superthermal neutron beam flux:
[0057] The duration of clinical treatment is determined by both the neutron beam flux and the concentration of boron-containing drugs in the tumor. If the concentration of boron-containing drugs in the tumor is high enough, the required neutron beam flux can be reduced; conversely, if the concentration of boron-containing drugs in the tumor is low, a high flux of hyperthermal neutrons is needed to deliver a sufficient dose to the tumor. The IAEA requires a hyperthermal neutron beam flux of greater than 102 hyperthermal neutrons per square centimeter per second. 9 At this flux, the neutron beam can roughly control the treatment time to within one hour for current boron-containing drugs. In addition to the advantages of patient positioning and comfort, the short treatment time can also make more effective use of the limited residence time of boron-containing drugs in the tumor.
[0058] 2. Fast neutron pollution:
[0059] Fast neutrons are considered contamination because they cause unnecessary doses to normal tissues. This dose is positively correlated with neutron energy; therefore, the concentration of fast neutrons should be minimized in neutron beam design. Fast neutron contamination is defined as the fast neutron dose per unit hyperthermic neutron flux. The IAEA recommends a fast neutron contamination dose of less than 2 x 10⁻⁶. -13 Gy-cm 2 / n.
[0060] 3. Photon pollution (gamma-ray pollution):
[0061] Gamma rays are strong penetrating radiation that non-selectively deposit dose on all tissues along the beam path. Therefore, reducing gamma ray content is a necessary requirement for neutron beam design. Gamma ray contamination is defined as the gamma ray dose per unit hyperthermic neutron flux. The IAEA recommends that gamma ray contamination be less than 2 x 10⁻⁶. -13 Gy-cm 2 / n.
[0062] 4. Ratio of thermal neutron to ultrathermal neutron flux:
[0063] Because thermal neutrons decay rapidly and have poor penetrating power, most of their energy is deposited in skin tissue after entering the body. Except for epidermal tumors such as melanoma, which require thermal neutrons as a neutron source for boron neutron capture therapy, the thermal neutron content should be reduced for deep tumors such as brain tumors. The IAEA recommends a thermal neutron to ultrathermal neutron flux ratio of less than 0.05.
[0064] 5. Neutron current to flux ratio:
[0065] The neutron current-to-flux ratio represents the directionality of the beam. A higher ratio indicates better forward neutron beam directionality. A highly forward-oriented neutron beam can reduce the dose to surrounding normal tissues caused by neutron divergence, and also improves the depth of treatment and the flexibility of positioning. The IAEA recommends a neutron current-to-flux ratio greater than 0.7.
[0066] The dose distribution within the tissue is obtained using a prosthesis, and the prosthesis beam quality factors are derived based on the dose-depth curves of normal tissue and tumors. The following three parameters can be used to compare the therapeutic benefits of different neutron beams.
[0067] 1. Effective treatment depth:
[0068] The tumor dose is equal to the depth at which the maximum dose to normal tissue is reached. Beyond this depth, tumor cells receive a lower dose than the maximum dose to normal tissue, thus losing the advantage of boron neutron capture. This parameter represents the penetrating power of the neutron beam; a greater effective treatment depth indicates a deeper tumor that can be treated, measured in centimeters.
[0069] 2. Effective therapeutic depth dose rate:
[0070] The effective treatment depth dose rate is equal to the maximum dose rate to normal tissue. Since the total dose received by normal tissue affects the total dose that can be delivered to the tumor, this parameter affects the treatment time. A higher effective treatment depth dose rate means that the irradiation time required to deliver a certain dose to the tumor is shorter. The unit is cGy / mA-min.
[0071] 3. Effective therapeutic dose ratio:
[0072] The ratio of the average dose received by tumor and normal tissue from the brain surface to the effective treatment depth is called the effective treatment dose ratio; the average dose can be calculated by integrating the dose-depth curve. The higher the effective treatment dose ratio, the better the therapeutic benefit of the neutron beam.
[0073] To provide a basis for comparison in the design of beam shapers, in addition to the five IAEA-recommended airborne beam quality factors and the three parameters mentioned above, the embodiments of this application also utilize the following parameters for evaluating the performance of neutron beam dosing:
[0074] 1. Irradiation time ≤ 30 min (the proton current used in the accelerator is 10 mA)
[0075] 2. 30.0 RBE-Gy can treat depths ≥7cm
[0076] 3. Maximum tumor dose ≥ 60.0 RBE-Gy
[0077] 4. Maximum dose to normal brain tissue ≤12.5 RBE-Gy
[0078] 5. Maximum skin dose ≤ 11.0 RBE-Gy
[0079] Note: RBE (Relative Biological Effectiveness) is a relative biological effect. Since photons and neutrons cause different biological effects, the dosage terms above are multiplied by the relative biological effects of different tissues to obtain the equivalent dose.
[0080] Referring to Figures 1 to 6, an embodiment of this application provides a collimation device 100, including: a base 10, a collimation part 20, and an identification device 30.
[0081] Figure 1 is a structural schematic diagram of an embodiment of the collimation device of the present invention; Figure 2 is a front structural schematic diagram of an embodiment of the base of the collimation device of the present invention; Figure 3 is a rear structural schematic diagram of an embodiment of the base of the collimation device of the present invention. As shown in Figures 1, 2, and 3, in one or more embodiments, the base 10 includes a stop unit 11 and an annular unit 12. The stop unit 11 may be configured as a generally annular plate-like member and has opposing first sides 13 (the front side of the paper in Figure 2) and second sides 14 (the front side of the paper in Figure 3). Alternatively, the stop unit 11 may also be configured in other suitable shapes, as long as a through hole for a neutron beam to pass through is formed in its middle portion. In one or more embodiments, the annular unit 12 surrounds the outside of the stop unit 11 and is fixedly connected to the stop unit 11. The connection method includes, but is not limited to, screwing, welding, or integrally formed together. The annular unit 12 is configured as a generally circular tubular member and has an inner wall 121 and an outer wall 122. Alternatively, the annular unit 12 can also be configured in other suitable shapes depending on the actual situation of the stop unit 11, so as to surround the outer side of the stop unit 11 circumferentially. In one or more embodiments, the stop unit 11 and the annular unit 12 form a groove adapted to receive the collimator 20. When the collimator 20 is disposed in the groove, the first side 13 of the stop unit 11 faces the collimator 20, and the second side 14 faces away from the collimator 20; and the inner wall 121 of the annular unit 12 faces the collimator 20, and the outer wall 122 faces away from the collimator 20. By limiting the first side 13 and the inner wall 121, the collimator 20 can be accurately positioned on the base 10 so that the beam exit on the collimator 20 can be precisely aligned with the neutron beam emitted from the beam shaper 700 (shown in FIG. 7). In addition, the base 10 can also omit the stop unit 11. In embodiments without the stop unit 11, the base 10 has opposing first sides 13 and second sides 14. In this configuration, the first side 13 faces the collimator 20, while the second side 14 faces away from the collimator 20. Alternatively, the groove 15 can be omitted, and other structures that can provide a limiting function can be used as needed. In summary, the structure and shape of the base 10 can be adapted to the collimator 20 and / or the beam shaper.
[0082] Referring again to Figure 1, in one or more embodiments, the collimator 20 includes a body 21 and optical components disposed within the body 21. The body 21 may include a frustum-shaped member 211 and a connecting disk 212 formed together to ensure structural strength. The frustum-shaped member 211 facilitates the mechanical and optical alignment of the optical components disposed therein. The connecting disk 212 surrounds the outside of the frustum-shaped member 211 for mounting into a recess 15. The frustum-shaped member 211 has a platform 2111 facing away from the base, and the platform 2111 forms a beam exit 2112 through which the neutron beam in the neutron capture therapy system 1 ultimately irradiates the treatment site of the patient. Alternatively, the collimator may also be configured in other suitable shapes as needed. In one or more embodiments, the collimator 20 may have various different models. Different collimators 20 may refer to different models of collimators 20. The collimator 20 may have different beam exits 2112, thicknesses, shapes, or optical components, but it must be ensured that different collimators 20 can be mounted on the base 10. Alternatively, different collimators 20 may be distinguished by features other than model designation. In one or more embodiments, the base 10 and the collimator 20 form a detachable connection, that is, the base 10 and the collimator 20 may be connected by a threaded connection, a snap-fit connection, a quick-clamp connection, or other detachable connection methods.
[0083] Figure 4 is a partial schematic diagram at point A of an embodiment of the base of the collimation device of the present invention shown in Figure 2; Figure 5 is a partial schematic diagram of the collimation portion of the collimation device of the present invention. The identification device 30 includes a first identification portion 31 disposed on the base 10 and a second identification portion 32 disposed on the collimation portion 20. The second identification portion 32 can match and respond to at least a portion of the first identification portion 31. Those skilled in the art will understand that matching includes, but is not limited to, structural matching (e.g., the mutual engagement between protrusions and grooves) and functional matching (e.g., the electrical connection formed between a plug and a socket). The matching response, i.e., after the matching status between the first identification portion 31 and the second identification portion 32 is determined, generates a signal change corresponding to the matching status, and other devices related to the identification device 30 can respond to this signal change to perform the next action. The first identification unit 31 and the second identification unit 32 are respectively disposed on the base 10 and the collimator 20, so that the collimator 20 can be identified immediately each time it is installed on the base 10. This eliminates the need for manual confirmation by the operator to determine whether the collimator 20 conforms to the current treatment plan, thereby reducing the time the operator spends at the beam shaping device and lowering the health risk of radiation exposure. After replacing the collimator 20, the model and other characteristics of the replaced collimator 20 can be identified based on the matching between the first identification unit 31 and the second identification unit 32, so as to determine whether the replaced collimator 20 conforms to the current patient's treatment plan, ensuring the safety of the equipment and treatment.
[0084] Referring again to FIG4, in one or more embodiments, the base 10 includes a first side 13 facing the collimation portion 20, and the first identification portion 31 is disposed on the first side 13. Alternatively, the first identification portion 31 may also be disposed at other suitable positions on the base 10 as needed to achieve a matching response with the second identification portion 32. For example, the first identification portion 31 may also be disposed on the inner wall 121 of the annular unit 12.
[0085] In one or more embodiments, the second identification part 32 is disposed on the surface of the collimator 20 facing the first side 13, so that when the collimator 20 is fixed to the first side 13, the second identification part 32 can match and respond with the first identification part 31. Alternatively, the second identification part 32 may also be disposed at other suitable positions on the collimator 20 as needed.
[0086] Referring again to Figures 4 and 5, in one or more embodiments, the first identification unit 31 includes a first identification unit 311, and the second identification unit 32 includes a second identification unit 321. The second identification unit 321 responds to a portion of the first identification unit 311, allowing for multiple matching scenarios between the first and second identification units 311. Different matching scenarios can indicate that different models of collimators 20 are mounted on the base 10, facilitating confirmation of whether the collimator 20 currently mounted on the base 10 is suitable for the patient's treatment plan. Alternatively, the first and second identification units 31 and 32 can also identify the collimator 10 mounted on the base 10 through other suitable methods.
[0087] In one or more embodiments, the first identification section includes nine first identification units 311, each of which can be matched with a corresponding second identification unit 321 to output a signal, forming different matching cases to distinguish the collimating section 20. For example, there are nine possible matching cases between each different first identification unit 311 and its corresponding second identification unit 321, which can be used to represent nine different collimating sections 20 being mounted on the base 10. Similarly, there are 36 possible matching cases between each combination of two different first identification units 311 and their corresponding two second identification units 321, which can be used to represent 36 different collimating sections 20 being mounted on the base 10. In alternative embodiments, the number of first identification units 311 can also be set to more than nine or less than nine, for example, three, four, five, or ten, depending on actual needs. In one or more embodiments, the plurality of first identification units 311 are arranged at intervals along the circumferential direction to make full use of the space on the stop unit 11 or the base 10. Alternatively, the first identification unit 311 may also be configured to be spaced apart in other suitable directions according to the actual shape of the base 10, such as spaced apart in a predetermined straight line direction.
[0088] In one or more embodiments, different collimating portions 20 are provided with different second identification units 321. Since the collimating portion 20 can only be accurately identified when the first identification unit 31 and the second identification unit 32 are accurately aligned, a positioning structure can be provided on the collimating portion 20. Furthermore, different second identification units 321 can be characterized by different distances from the positioning structure. In some embodiments, the positioning structure can be a second universal unit 322. Specifically, when the distance between the second identification unit 321 and the second universal unit 322 is short, after the second universal unit 322 is aligned with the first universal unit 312, the second identification unit 321 will be matched with the first identification unit 311 that is closer to the first universal unit 312, forming a matching situation, indicating that a certain type of collimating portion 20 is connected to the base 10. Conversely, when the distance between the second identification unit 321 and the second general unit 322 is relatively large, after the second general unit 322 and the first general unit 312 are positioned and docked, the second identification unit 321 will correspondingly match with the first identification unit 311, which is further away from the first general unit 312, forming another different matching situation, indicating that another type of collimator 20 is connected to the base 10. Alternatively, the second identification units 321 on different collimators 20 can also be configured to have other differences, such as different numbers, to achieve the effect of distinguishing different collimators 20.
[0089] Referring again to Figure 5, in one or more embodiments, each collimator 20 has two second identification units 321 to match the corresponding two first identification units 311. Alternatively, the number of second identification units 321 on each collimator 20 can be configured to other suitable numbers. When there are fewer types of collimators 20, the number of second identification units 321 on each collimator 20 can be set to one to match the corresponding one first identification unit 311; when there are more types of collimators 20, the number of second identification units 321 can be set to three, four, etc., to match at least some of the first identification units 311. Alternatively, different numbers of second identification units 321 on different collimators 20 can also be set, which also helps to distinguish different collimators 20. In one or more embodiments, the second identification units 321 are also arranged at intervals along the circumferential direction to ensure good contact with the first identification units 311. Alternatively, the second identification units 321 can also be arranged in other ways to facilitate matching with the first identification units 311.
[0090] In one or more embodiments, the first identification unit further includes a first general-purpose unit 312; and the second identification unit further includes a second general-purpose unit 322. The first general-purpose unit 321 and the second general-purpose unit 322 are correspondingly configured and can be matched with each other to assist in the identification of the collimation unit 20. For example, "the first general-purpose unit 312 and the second general-purpose unit 322 are matched" can be used as a positioning reference to make the first identification unit 311 and the second identification unit 321 accurately dock; it can also be used as a prerequisite for "identifying the collimation unit 20 by the matching of the first identification unit 311 and the second identification unit 321", that is, in response to the matching of the first general-purpose unit 312 and the second general-purpose unit 322, the collimation unit 20 is identified to ensure the accuracy of the identification of the collimation unit 20, thereby further ensuring the treatment effect of the patient and the safety of the device; or the matching response of the first general-purpose unit 312 and the second general-purpose unit 322 can be set for other purposes to assist in the identification of the collimation unit 20.
[0091] Referring again to Figure 5, in one or more embodiments, the first identification unit includes one first general-purpose unit 312, and correspondingly, the number of second general-purpose units 322 is also set to one. Alternatively, the combination of general-purpose units can also be set to other suitable numbers, such as two first general-purpose units 312 corresponding to two second general-purpose units 322, three first general-purpose units 312 corresponding to three second general-purpose units 322, etc., to improve the security or positioning accuracy of the device.
[0092] In one or more embodiments, the second universal unit 322 disposed on different collimators 20 is identical, so as to match the first universal unit 312 and achieve the effect of precise positioning or ensuring device safety. Alternatively, the second universal unit 322 on different collimators 20 may also have different configurations, such as different numbers or shapes, to achieve other functions.
[0093] In one or more embodiments, both the first identification unit 311 and the first general-purpose unit 312 can be configured as interfaces; for example, the interface is a metal conductive sheet. Both the second identification unit 321 and the second general-purpose unit 322 can be configured as terminals; for example, the terminals are metal pins, which can form abutment contact with the interface to transmit electrical signals. Alternatively, only the first identification unit 311 and the second identification unit 321 can be configured as a combination of terminals and interfaces, while the first general-purpose unit 312 and the second general-purpose unit 322 can be configured as matching positioning structures. Of course, the correspondence between the interfaces and terminals on the first identification part 31 and the second identification part 32 can be interchanged. For example, both the first general-purpose unit 312 and the first identification unit 311 can be configured as terminals, and both the second general-purpose unit 322 can be configured as interfaces; or one of the first general-purpose unit 312 and the first identification unit 311 can be configured as a terminal, and the corresponding second identification part 32 can be modified accordingly. In alternative embodiments, the identification device 30 can also be configured with other suitable structures to transmit signal changes. For example, a light source and a corresponding photosensitive element can be provided within the interface, and the terminal can be configured as a light-shielding element to block the light source. When the terminal and interface respond to a matching interaction, the changing electrical signal is transmitted through the photosensitive element. Similarly, an infrared emitting device and an infrared receiving device can be respectively provided on the first identification unit 31 and the second identification unit 32, or a magnetic component and a magnetic field sensing device can be respectively provided on the first identification unit 31 and the second identification unit 32, or other feasible devices can be used as needed to ensure the matching response between the first identification unit 31 and the second identification unit 32.
[0094] Furthermore, during irradiation therapy, to ensure sufficient irradiation intensity, the patient's treatment area needs to be brought as close as possible to the collimator to maintain a reasonable source-skin distance and thus ensure the required irradiation intensity. However, in existing neutron capture therapy systems, problems often arise where the collimator comes into contact with the patient's skin or bone and is damaged, or where malfunctions in the internal transmission mechanism of the neutron capture therapy system cause damage to the collimator and other equipment.
[0095] Figure 6 is a partial schematic diagram at point B of an embodiment of the base of the collimation device of the present invention shown in Figure 3. In one or more embodiments, the collimation device 100 further includes an anti-collision device to address the problems of the collimation part 20 colliding with the patient or mechanical malfunction damaging the collimation part 20. The anti-collision device can be disposed on the base 10 to reduce the increased production cost required to dispose of it on the collimation part 20. The anti-collision device is used to output a prompt signal when the collimation part 20 is subjected to force, prompting the operator to adjust the device in time to avoid injuring the patient. Alternatively, the anti-collision device can be disposed on the collimation part 20 as needed; or the anti-collision device can be omitted. As shown in Figure 6, in one or more embodiments, the anti-collision device includes a sensing device 40. The sensing device 40 is configured as a pressure sensor to output a pressure signal to determine the contact force between the current collimation part 20 and the patient's treatment site. Alternatively, the sensing device 40 can be disposed of as other suitable sensors, such as a distance sensor; or the sensing device can be omitted as needed. In one or more embodiments, the base 10 includes a second side 14 facing away from the collimator 20, on which the sensing device 40 is disposed to avoid wear and tear on the sensing device 40 due to frequent collimator replacements, thereby extending the service life of the device. Alternatively, the sensing device may also be disposed at other suitable locations on the collimator 100.
[0096] In one or more embodiments, the anti-collision device further includes an alarm device. In one or more embodiments, the base 10 has a first side 13 facing the collimator 20, and the alarm device is disposed on the first side 13 to make the alarm signal more easily perceived by the operator. Alternatively, the alarm device may be disposed at other locations on the collimator 100 that are easily perceived by the operator. The alarm device is used to output a warning signal when the force exerted on the collimator 20 exceeds a preset range. The force exerted on the collimator 20 can be obtained by the sensing device 40. The warning signal includes, but is not limited to, light signals, sound signals, etc.
[0097] In one or more embodiments, the preset range can be set to 0-100g. When the force is between 0-100g, the alarm device issues a first alarm signal. When the alarm device issues the first alarm signal, it indicates that the patient's treatment area has contacted the collimator 20. At this time, the source-skin distance and irradiation intensity of the neutron beam are within a suitable range. The patient's current position can be maintained, or the transmission mechanism can continue to operate to move the patient's treatment area further closer to the collimator 20. When the force exceeds 100g, the alarm device issues a second alarm signal. The warning level of the second alarm signal is higher than that of the first alarm signal; for example, the volume of the second alarm signal is greater than that of the first alarm signal, or the brightness of the second alarm signal is greater than that of the first alarm signal. When the alarm device issues the second alarm signal, it indicates that the contact pressure between the patient's treatment area and the collimator 20 is relatively high. Continuing to operate the transmission mechanism may cause injury to the patient or damage to the collimator. Therefore, after the alarm device issues the second alarm, the transmission mechanism can be reversed to move the patient backward until the second alarm signal switches to the first alarm signal or no alarm signal is issued. Alternatively, the preset range can be set to other suitable force ranges according to actual needs.
[0098] In one or more embodiments, the alarm device is configured as a light strip fixed to the base 10 and circumferentially surrounding the collimator 20. Exemplarily, the light strip is fixed to the outside of the annular unit 12 to prevent the annular unit 12 from obstructing the operator's view. Alternatively, the light strip may be positioned at other suitable locations on the collimator 100. In one or more embodiments, the light strip includes six independent indicator lights. When a first alarm signal is issued, a small portion (e.g., half) of the indicator lights in the light strip illuminates, i.e., three indicator lights illuminate; when a second alarm signal is issued, most (e.g., all) of the indicator lights in the light strip illuminate. Alternatively, the number of indicator lights may be set to other suitable numbers, such as four, eight, etc. In alternative embodiments, the alarm device may also be configured to combine sound and light signals or use only sound signals for alarming. Exemplarily, when a first alarm signal is issued, the indicator lights illuminate; when a second alarm signal is issued, the indicator lights remain illuminated and a buzzer sound is emitted.
[0099] Referring again to Figure 1, in one or more embodiments, the base 10 further includes a signal output section 50, which is electrically connected to the identification device 30. The signal output section 50 outputs the matching status of the identification device 30 to other controllers to determine whether the collimator 20 currently connected to the base 10 matches the current patient's treatment plan. Exemplarily, the signal output section 50 is an aviation connector to ensure the stability of the connection between the collimator 100 and other devices. Alternatively, the signal output section 50 can also be used to output other information, including but not limited to the force exerted on the collimator 20. In one or more embodiments, the base 10 includes an annular unit 12 and a stop unit 11, and the annular unit 12 and the stop unit 11 form a groove 15 for accommodating the collimator 20. The annular unit 12 is disposed on the circumferential edge of the stop unit 11 and has an inner wall 121 facing the collimator 20 and an outer wall 122 facing away from the collimator 20. The signal output section 50 is located on the outer side of the outer wall 122 to facilitate modular manufacturing or assembly of the collimation device 100, which is then integrally mounted onto the beam shaper 700. Alternatively, the signal output section 50 may also be located at other suitable positions on the base 10.
[0100] Referring again to Figure 2, in one or more embodiments, the collimating device 100 further includes a locking mechanism 60 for securing the collimating portion 20 to the base 10. In one or more embodiments, the base 10 includes an annular unit 12 and a stop unit 11, and the annular unit 12 and the stop unit 11 form a groove for receiving the collimating portion 20. The annular unit 12 is disposed on the circumferential edge of the stop unit 11 and has an inner wall 121 facing the collimating portion 20 and an outer wall 122 facing away from the collimating portion 20. Alternatively, the locking mechanism 60 may be disposed at other suitable locations on the base 10; or the locking mechanism 60 may be omitted as needed.
[0101] Figure 7 is a structural schematic diagram of an embodiment of the neutron capture therapy system of the present invention; Figure 8 is a front view of an embodiment of the neutron capture therapy system of the present invention. This application also provides a neutron capture therapy system 1. As shown in Figure 7, the neutron capture therapy system 1 includes an accelerator 800 for generating a charged particle beam P, a neutron generating unit 900 for generating a neutron beam after irradiation by the charged particle beam P, a beam shaping body 700, and a collimating device 100. The neutron generating unit 900 generates a neutron beam N after irradiation by the charged particle beam P, and the collimating device 100 concentrates the neutrons generated by the neutron generating unit 900 for irradiation.
[0102] As shown in Figure 8, a collimating device 100 is disposed on a beam shaper 700, enabling the neutron beam formed in the beam shaper 700 to irradiate the patient's treatment site through the beam outlet 2112 on the collimating device 100. In one or more embodiments, the beam shaper 700 includes a signal receiving unit 71. The signal receiving unit 71 is communicatively connected to the signal output unit 50 to receive the matching status of the identification device 30, the pressure signal from the sensing device 40, etc., and transmit them to the controller of the neutron capture therapy system 1.
[0103] The collimation device 100 includes a base 10 and a collimation section 20. In one or more embodiments, the collimation section 20 can have various different models. Different collimation sections 20 can refer to different models of collimation sections 20. The collimation section 20 can have different beam exits 2112, thicknesses, shapes, or optical components, etc., but it must be ensured that different collimation sections 20 can be mounted on the base 10. Alternatively, different collimation sections 20 can also be distinguished by features other than model number. In one or more embodiments, the base 10 and the collimation section 20 form a detachable connection, that is, the base 10 and the collimation section 20 can be connected by a threaded connection, a snap-fit connection, a quick-clamp connection, or other detachable connection methods.
[0104] The collimation device 100 also includes an identification device 30. The identification device 30 is used to identify different collimators 20 and includes a first identification part 31 disposed on the base 10 and a second identification part 32 disposed on the collimator 20. The second identification part 32 can match and respond to at least a portion of the first identification part 31, forming different matching situations. By disposing the first identification part 31 and the second identification part 32 on the base 10 and the collimator 20 respectively, the current collimator 20 can be identified immediately each time it is installed on the base 10, eliminating the need for manual confirmation by the operator regarding whether the collimator 20 conforms to the current treatment plan. This reduces the time the operator spends at the beam exit of the beam shaper 700, lowering the health risk of radiation exposure for the operator. After replacing the collimator 20, the model and other characteristics of the replaced collimator 20 can be identified based on the matching situation between the first identification part 31 and the second identification part 32, facilitating the determination of whether the replaced collimator 20 conforms to the current patient's treatment plan and ensuring the safety of the equipment and treatment.
[0105] In one or more embodiments, the first identification unit 31 includes a first identification unit 311, and the second identification unit 32 includes a second identification unit 321. The second identification unit 321 can be matched with a portion of the first identification unit 311, allowing for multiple matching scenarios between the first identification unit 311 and the second identification unit 321. Different matching scenarios can indicate that different models of collimators 20 are mounted on the base 10, facilitating confirmation of whether the collimator 20 currently mounted on the base 10 is suitable for the treatment plan of the patient to be treated. Alternatively, the first identification unit 31 and the second identification unit 32 can also identify the collimator 10 mounted on the base 10 through other suitable methods.
[0106] In one or more embodiments, the first identification section includes nine first identification units 311, each of which can be matched with a corresponding second identification unit 321 to output a signal, forming different matching cases to facilitate the differentiation of the collimation section 20. For example, there are nine possible matching cases between each different first identification unit 311 and a corresponding second identification unit 321, which can be used to represent nine different collimation sections 20 being mounted on the base 10. Similarly, there are 36 possible matching cases between every two different first identification units 311 and the corresponding two second identification units 321, which can be used to represent 36 different collimation sections 20 being mounted on the base 10. In alternative embodiments, the number of first identification units 311 may also be set to more than nine or less than nine, for example, three, four, five, or ten, depending on actual needs. In one or more embodiments, the plurality of first identification units 311 are arranged at intervals along the circumferential direction to fully utilize the space on the stop unit 11 or the base 10. Alternatively, the first identification unit 311 may also be configured to be spaced apart in other suitable directions according to the actual shape of the base 10, such as spaced apart in a predetermined straight line direction.
[0107] In one or more embodiments, different collimating portions 20 are provided with different second identification units 321. Since the collimating portion 20 can only be accurately identified when the first identification unit 31 and the second identification unit 32 are accurately aligned, a positioning structure can be provided on the collimating portion 20. Furthermore, different second identification units 321 can be characterized by different distances from the positioning structure. In some embodiments, the positioning structure can be a second universal unit 322. Specifically, when the distance between the second identification unit 321 and the second universal unit 322 is short, after the second universal unit 322 is positioned and aligned with the first universal unit 312, the second identification unit 321 will correspondingly match with the first identification unit 311 that is closer to the first universal unit 312, forming a matching situation, indicating that a certain type of collimating portion 20 is connected to the base 10. Conversely, when the distance between the second identification unit 321 and the second general unit 322 is relatively large, after the second general unit 322 and the first general unit 312 are positioned and docked, the second identification unit 321 will correspondingly match with the first identification unit 311, which is further away from the first general unit 312, forming another different matching situation, indicating that another type of collimator 20 is connected to the base 10. Alternatively, the second identification units 321 on different collimators 20 can also be configured to have other differences, such as different numbers, to achieve the effect of distinguishing different collimators 20.
[0108] In one or more embodiments, the first identification unit further includes a first general-purpose unit 312; and the second identification unit 32 further includes a second general-purpose unit 322. The first general-purpose unit 321 and the second general-purpose unit 322 are correspondingly configured and can be matched with each other to assist in the identification of the collimation unit 20. Exemplarily, "the first general-purpose unit 312 and the second general-purpose unit 322 are matched" can be used as a positioning reference, so that the first identification unit 311 and the second identification unit 321 are precisely aligned; it can also be used as a prerequisite for "identifying the collimation unit 20 by the matching of the first identification unit 311 and the second identification unit 321", that is, in response to the matching of the first general-purpose unit 312 and the second general-purpose unit 322, the collimation unit 20 is identified to ensure the accuracy of identifying the collimation unit 20, thereby further ensuring the treatment effect of the patient and the safety of the device; or the matching of the first general-purpose unit 312 and the second general-purpose unit 322 can be configured for other purposes to assist in the identification of the collimation unit 20.
[0109] In one or more embodiments, the second universal unit 322 disposed on different collimators 20 is identical, so as to match the first universal unit 312 and achieve the effect of precise positioning or ensuring device safety. Alternatively, the second universal unit 322 on different collimators 20 may also have different configurations, such as different numbers or shapes, to achieve other functions.
[0110] This application also provides a method for identifying a collimation device. The collimation device 100 includes a base 10 and a collimation part 20; the collimation device 100 further includes an identification device 30, the identification device 30 includes a first identification part 31 disposed on the base 10 and a second identification part 32 correspondingly disposed on the collimation part 20, the second identification part 32 can match and respond with at least a portion of the first identification part 31.
[0111] Figure 8 is a flowchart illustrating the identification method of the collimation device of the present invention. As shown in Figure 8, after the identification method of this application begins, step S1 is executed first, that is, the collimation part 20 is placed on the base 10, so that the second identification part 32 matches a portion of the first identification part 31. In one or more embodiments, the collimation part 20 is placed on the base 10 by a threaded connection, a snap-fit connection, a quick-clamp connection, or other detachable connection methods. Then, step S2 is executed, that is, in response to the second identification part 32 matching a portion of the first identification part 31, the identification device 30 identifies the collimation part 20. The identification device 30 can identify at least two or more different collimation parts 20. In one or more embodiments, the contact positions of the second identification part 32 and the first identification part 31 on different collimation parts 20 are different, thereby distinguishing different collimation parts 20. Alternatively, different collimation parts 20 can also be distinguished by other suitable methods. Then, step S3 is executed, that is, it is determined whether the identified collimation part 20 matches the treatment plan. At this point, the identification method of this application has been completed, and the patient can receive neutron beam irradiation that best matches their treatment plan.
[0112] In one or more embodiments, the identification device 30 includes a general unit and an identification unit. The step "Identification device 30 identifies collimator 20" includes: when both the general unit and the identification unit simultaneously meet preset conditions, identifying different collimators 20 through the identification unit. Exemplarily, the preset conditions can be set such that both the general unit and the identification unit are in a matching response state, that is, the first general unit 312 disposed on the base 10 and the second general unit 322 disposed on the collimator 20 are mutually matched, and simultaneously the first identification unit 311 disposed on the base 10 and the second identification unit 321 disposed on the collimator 20 are also mutually matched. In this state, the matching status of the first identification unit 31 and the second identification unit 32 can be used to identify the model or parameters of the collimator 20. Alternatively, other suitable methods can also be used to ensure the accuracy of the identification.
[0113] The technical solution of the present invention has been described above with reference to the preferred embodiments shown in the accompanying drawings. However, it will be readily understood by those skilled in the art that the scope of protection of the present invention is obviously not limited to these specific embodiments. Without departing from the principles of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after such changes or substitutions will all fall within the scope of protection of the present invention.
Claims
1. A collimating device, characterized by, The collimator device comprises a base and a collimating part, the collimating part and the base are detachably connected, the collimator device further comprises an identification device, the identification device is used for identifying the collimating part, the identification device comprises a first identification part arranged on the base and a second identification part correspondingly arranged on the collimating part, and the second identification part is matchable with at least part of the first identification part.
2. The collimating device of claim 1, wherein, The first identification part comprises a first identification unit, the second identification part comprises a second identification unit, and the second identification unit is matchable with at least part of the first identification unit.
3. The collimating device of claim 2, wherein, Different collimating parts are correspondingly provided with different second identification units.
4. The collimating device of claim 2, wherein, A plurality of first identification units are arranged in an interval or in a circumferential direction.
5. The collimating device of claim 2, wherein, The first identification part comprises a first universal unit, the second identification part comprises a second universal unit, and the first universal unit and the second universal unit are correspondingly arranged, wherein the second universal units on different collimating parts are the same.
6. The collimating device of claim 1, wherein, The second identification part is in abutting contact with at least part of the first identification part.
7. The collimating device of claim 1, wherein, The collimator device further comprises an anti-collision device arranged on the base, and the anti-collision device is used for outputting a prompt signal when the collimating part is subjected to a force.
8. The collimating device of claim 7, wherein, The anti-collision device comprises a sensing device, and the sensing device is used for outputting a pressure signal when the collimating part is subjected to a force.
9. The collimating device of claim 7, wherein, The anti-collision device comprises an alarm device, and the alarm device is used for outputting a light signal when the collimating part is subjected to a force exceeding a preset range.
10. A neutron capture therapy system characterized by, The collimator device comprises a base and at least one collimating part, the collimating part and the base are detachably connected, the collimator device further comprises an identification device, the identification device is used for identifying different collimating parts, the identification device comprises a first identification part arranged on the base and a second identification part correspondingly arranged on the collimating part, and the second identification part is matchable with at least part of the first identification part.
11. The neutron capture therapy system of claim 10, wherein, The first identification part comprises a first identification unit, the second identification part comprises a second identification unit, and the second identification unit is matchable with at least part of the first identification unit.
12. The neutron capture therapy system of claim 11, wherein, Different collimating parts are correspondingly provided with different second identification units.
13. The neutron capture therapy system of claim 11, wherein, The first identification part comprises a first universal unit, the second identification part comprises a second universal unit, and the first universal unit and the second universal unit are correspondingly arranged, wherein the second universal units on different collimating parts are the same.
14. The neutron capture therapy system of claim 10, wherein, The second identification part is in abutting contact with at least part of the first identification.
15. A method for identifying a collimating device, characterized in that, The collimator device comprises a base and a collimating part; the collimator device further comprises an identification device, the identification device comprises a first identification part arranged on the base and a second identification part correspondingly arranged on the collimating part, and the second identification part is matchable with at least part of the first identification part; The identification method comprises: arranging the collimating part on the base, and matching the second identification part with part of the first identification part; in response to the second identification part matching part of the first identification part, the identification device identifies the collimating part; judging whether the identified collimating part matches a treatment plan; and The identification device can identify at least two different collimating sections.
16. The identification method of the collimating device according to claim 15, characterized in that, The identification device comprises a general unit and an identification unit, and the "identification device identifies collimating sections" comprises: When the general unit and the identification unit simultaneously meet preset conditions, the identification unit identifies different collimating sections.