Blood glucose and blood oxygen multi-parameter detection chip and wearable device

Abstract

The present application provides a blood glucose and blood oxygen multi-parameter detection chip and a wearable device. The present application relates to the technical field of semiconductors. The multi-parameter detection chip comprises a coupler, a gating device, and a plurality of outlets that are optically connected in sequence and integrated together, as well as a light source capable of emitting light of different wavelengths and a detector. The coupler is configured for coupling the light of different wavelengths emitted by the light source to the gating device. The gating device selects the light of different wavelengths and allows the light to enter the corresponding outlets so that the light exits by means of the outlets. The detector is configured for receiving the light that exits by means of the outlets and is then reflected or transmitted back. Arranging an array of outlets and replacing traditional point detection with plane detection can greatly improve the detection accuracy. In addition, the wavelength coverage of the blood glucose and blood oxygen multi-parameter detection chip spans the entire visible to near-infrared light waveband, so that the chip can perform multi-wavelength detection, thereby enabling multi-parameter measurement.

Description

A multi-parameter detection chip for blood glucose and blood oxygen and a wearable device

[0001] This application claims priority to Chinese Patent Application No. 202410866131.1, filed on June 28, 2024, entitled "A Multi-parameter Detection Chip for Blood Glucose and Oxygen and Wearable Device", the entire contents of which are incorporated herein by reference. Technical Field

[0002] This application relates to the field of semiconductor technology, specifically to a multi-parameter detection chip for blood glucose and blood oxygen and a wearable device. Background Technology

[0003] With the improvement of people's living standards, obesity and aging are becoming increasingly serious problems. Therefore, multi-parameter health monitoring anytime and anywhere has become an urgent need. Monitoring multiple parameters such as heart rate, respiration, blood oxygen, blood pressure, hemoglobin, and diabetes is very important for patients with chronic diseases.

[0004] Currently, blood pressure, hemoglobin, and blood glucose tests all require separate instruments for measurement. Common smart wearable devices generally only have functions for detecting heart rate, respiration, and blood oxygen, and cannot achieve high-precision measurement of blood pressure, hemoglobin, and diabetes test indicators. Summary of the Invention

[0005] The purpose of this application is to provide a multi-parameter blood glucose and blood oxygen detection chip and a wearable device that can integrate the monitoring of multiple parameters, and has high detection accuracy, compact device and low power consumption.

[0006] One aspect of this application provides a multi-parameter blood glucose and blood oxygen detection chip, including a coupler, a selector, and multiple emission ports that are sequentially optically connected and integrated together, as well as a light source and a detector capable of emitting light of different wavelengths; the coupler is used to couple light of different wavelengths emitted from the light source to the selector, the selector selects light of different wavelengths to enter the corresponding emission port so as to be emitted out through the emission port, and the detector is used to receive the light that returns after being emitted through the emission port and after being reflected or transmitted.

[0007] Optionally, there are multiple light sources and multiple gates. Different light sources emit light of different wavelengths. Each gate includes an input terminal and multiple output terminals. Each light source is connected to the input terminal of a gate through a coupler. The multiple output terminals of the gate are connected to different emission ports. The gate controls whether the light emitted by the light source is emitted from the emission port.

[0008] Optionally, multiple exit ports are arranged in a ring around the detector.

[0009] Optionally, there are multiple detectors arranged in a rectangular array, with the emission ports distributed around the multiple detectors.

[0010] Optionally, there are multiple light sources, gating devices, and detectors. Different light sources emit light of different wavelengths, and the gating device includes one input terminal and multiple output terminals.

[0011] Each light source is connected to the input of a gate via a coupler, and multiple outputs of the same gate are arranged around the same detector.

[0012] The light emitted from one of the multiple light sources passes through a coupler to the corresponding gate. The gate controls the light transmitted from the coupler to be emitted from the corresponding outlet. The detector receives the light emitted from the outlets around it and transmits it back after reflection or transmission.

[0013] Optionally, there are multiple light sources, gating devices, and detectors. Different light sources emit light of different wavelengths, and the gating device includes one input terminal and multiple output terminals.

[0014] Each light source is connected to the input of a gate via a coupler, and multiple outputs of the same gate are located next to different detectors.

[0015] The light emitted by one of the multiple light sources passes through a coupler to the corresponding gate. The gate controls the light transmitted from the coupler to be emitted from the corresponding outlet. Multiple detectors jointly receive the light emitted from the outlets around them and transmit it back after reflection or transmission.

[0016] Optionally, the coupler, selector, output port, and waveguide are fabricated on the substrate of the blood glucose and blood oxygen multi-parameter detection chip using semiconductor technology, and the substrate is made of nitride material.

[0017] Optionally, the nitride materials include silicon nitride, germanium nitride, gallium nitride, and group III or group V nitride materials.

[0018] Optionally, the coupler is an end-face coupler or a grating coupler, with the light source positioned near the coupler.

[0019] Optionally, the wavelength range of the light emitted by the light source of the blood glucose and blood oxygen multi-parameter detection chip is 400nm to 2500nm.

[0020] Optionally, the outlet is a grating-shaped outlet.

[0021] In another aspect of this application, a wearable device is provided, worn on a detection object, including the above-mentioned blood glucose and blood oxygen multi-parameter detection chip and processing system. The blood glucose and blood oxygen multi-parameter detection chip is located on the light-emitting side of the light source; the processing system is electrically connected to multiple light sources, selectors, and detectors respectively.

[0022] The light emitted from the light source is emitted through the outlet to the object being detected, and then reflected or transmitted by the object to the detector. The signal received by the detector is processed by the processing system to obtain detection data of different wavelengths, and finally obtains multi-parameter data of the object being detected.

[0023] The blood glucose and oxygenation multi-parameter detection chip provided in this application includes a coupler, a selector, and multiple emission ports that are sequentially optically connected and integrated, as well as a light source and a detector capable of emitting light of different wavelengths. The coupler couples different wavelengths of light emitted from the light source to the selector, which selects different wavelengths of light to enter the corresponding emission ports for emission. The detector receives the light that returns after reflection or transmission following emission. This blood glucose and oxygenation multi-parameter detection chip, through its arrayed emission port layout, uses surface detection instead of traditional point detection, greatly improving detection accuracy. Furthermore, the chip covers the entire wavelength range from visible light to near-infrared, enabling multi-wavelength detection and thus achieving multi-parameter measurement. For example, it can measure parameters such as heart rate, blood oxygen, cuffless blood pressure, non-invasive hemoglobin, and non-invasive blood glucose.

[0024] When the blood glucose and blood oxygen multi-parameter detection chip of this application is applied to wearable devices, it is used in conjunction with a light source capable of emitting different wavelengths. The light emitted from the light source is transmitted to the detection object through the emission port, and then reflected or transmitted by the detection object to the detector. After the signal received by the detector is amplified, filtered, and extracted by the processing system, detection data of different wavelengths are obtained, and finally, multi-parameter data of the detection object is obtained. The wearable device of this application can transform the currently common single-item detection into multi-parameter detection of blood glucose and blood oxygen using a multi-parameter detection chip, with high detection accuracy, and also has the advantages of excellent performance, compact size, and low production cost. Attached Figure Description

[0025] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments of this application will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0026] Figure 1 is a schematic diagram of the structure of the blood glucose and blood oxygen multi-parameter detection chip provided in this embodiment;

[0027] Figure 2 is a schematic diagram of the structure of the blood glucose and blood oxygen multi-parameter detection chip in Embodiment 2 provided in this embodiment;

[0028] Figure 3 is one of the schematic diagrams of the wearable device structure provided in this embodiment;

[0029] Figure 4 is the second schematic diagram of the wearable device structure provided in this embodiment. Detailed Implementation

[0030] The technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings.

[0031] In the description of this application, it should be noted that the terms "inner" and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the product is in use. They are used only for the convenience of describing this application and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the terms "first," "second," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0032] It should also be noted that, unless otherwise explicitly specified and limited, the terms "setup" and "connection" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0033] Currently, blood pressure, hemoglobin, and blood glucose measurements all require separate instruments. Common smart wearable devices only use 525nm green light for heart rate measurement and 660nm and 880nm wavelengths for blood oxygen measurement. High-precision measurements of cuffless blood pressure and non-invasive blood glucose are still not possible. A major reason for this is that it's difficult to ensure the same location is detected on the wrist each time; different detection locations lead to poor accuracy in non-invasive blood glucose testing.

[0034] To address the aforementioned issues, this application provides a multi-parameter blood glucose and oxygenation detection chip 2, which enables non-invasive, accurate multi-parameter measurement and transforms the currently common single-point detection into area array detection. In addition to blood glucose detection, the multi-parameter blood glucose and oxygenation detection chip 2 of this application can also detect other health indicators such as heart rate, blood oxygen, cuffless blood pressure, and non-invasive hemoglobin.

[0035] Specifically, please refer to Figure 1, which shows an embodiment of the multi-parameter blood glucose and oxygenation detection chip 2 provided in this application. The multi-parameter blood glucose and oxygenation detection chip 2 includes a coupler 21, a selector 22, and multiple emission ports 23 connected in sequence, as well as a light source 1 and a detector 24 capable of emitting light of different wavelengths. The coupler 21 is used to couple light of different wavelengths emitted from the light source 1 to the selector 22. The selector 22 selects light of different wavelengths to enter the corresponding emission port 23 so that it can be emitted out through the emission port 23. The detector 24 is used to receive the light that returns after being reflected or transmitted after being emitted through the emission port 23.

[0036] In this embodiment, the multiple outlets 23 are arranged in an array. Here, they are arranged in a circular array. In other embodiments, the multiple outlets 23 may not be arranged in an array, or they may be arranged in an array of other shapes, such as a rectangular array.

[0037] The selector 22 is used to transmit the light from the coupler 21 to the output port 23. The light transmitted from the coupler 21 is multi-path; the selector 22 can select one path of light to pass through and then transmit it to the desired output port 23. This multi-path light can be achieved by splitting the light transmitted by one coupler 21 into multiple paths, or by using multiple couplers 21. When using the scheme of splitting the light transmitted by one coupler 21 into multiple paths, the light source 1 can be a wavelength-tunable laser. When multiple couplers 21 are connected to the selector 22 respectively, the light source 1 can be multiple lasers.

[0038] The light source 1 can be a chip integrated with the coupler 21, the selector 22, and multiple emission ports 23, or it can be a separate chip. Regardless of whether the light source 1 is a separate chip or integrated with other chips, the light source 1 is optically connected to the coupler 21. Similarly, the detector 24 can be a chip integrated with the coupler 21, the selector 22, and multiple emission ports 23, or it can be a separate chip.

[0039] Coupler 21 can be a grating coupler, an end-face coupling device, or a coupling waveguide, and the light source 1 is located near coupler 21. The emission port 23 can be a grating-shaped emission port or a vertical optical port.

[0040] In this embodiment, there are multiple light sources 1. For example, light source 1 includes three light sources: a first light source 11, a second light source 12, and a third light source 13. The light emitted by the first light source 11, the second light source 12, and the third light source 13 has different wavelengths and can be used to measure different parameters. For example, the light emitted by the first light source 11 has a wavelength of 525 nm and can be used for heart rate measurement. The light emitted by the second light source 12 has a wavelength of 880 nm and can be used for blood oxygen measurement. The light emitted by the third light source 13 is near-infrared in wavelength, with a wavelength range between 900 nm and 2500 nm, and can be used for hemoglobin and blood glucose measurement, etc. In this embodiment, light source 1 is an external light source; in other embodiments, light source 1 can also be integrated with other components in the blood glucose and blood oxygen multi-parameter detection chip 2.

[0041] In this embodiment, there are multiple light sources 1, selectors 22, and couplers 21, and the number of each is the same. Each selector 22 has one input terminal 22a and multiple output terminals 22b. Each light source 1 is connected to the input terminal 22a of a selector 22 via a coupler 21. The multiple output terminals 22b of the selector 22 are respectively connected to different emission ports 23. The selector 22 controls whether the light emitted by the light source 1 is emitted from the emission port 23.

[0042] For example, each input terminal 22a is optically connected to a corresponding coupler 21. Multiple output terminals 22b of each selector 22 are optically connected to an exit port 23. Light emitted from the light source 1 enters the blood glucose and blood oxygen multi-parameter detection chip 2 through the coupler 21, and then enters the input terminal 22a of the selector 22. When different output terminals 22a of the selector 22 are open, the corresponding exit port 23 is selected, allowing light to exit from the output terminal 22a of the selector 22 through the corresponding exit port 23. Therefore, controlling the selector 22 can achieve the selection of light, that is, control which exit port 23 the light exits from.

[0043] In other embodiments, if the light source 1 is a tunable laser, only one selector 22 can be used. In operation, the tunable laser emits different wavelengths at different times, and the detector 24 can collect the detection signal of the corresponding wavelength within the corresponding time period. Of course, in other embodiments, the light emitted by multiple light sources 1 (first light source 11, second light source 12, and third light source 13) can also be coupled into the same selector 22. During operation, the first light source 11, second light source 12, and third light source 13 operate in a time-sharing manner. That is, at any given time, only one of the first light source 11, second light source 12, and third light source 13 emits light. This allows for detection using light of different wavelengths, and thus enables the measurement of multiple parameters.

[0044] In this embodiment, detector 24 is a circular detector array, which is a circular array formed by multiple detectors. In other embodiments, detector 24 can also be a detector array of other shapes, such as a rectangle. Detector 24 can also be a single detector.

[0045] The same selector 22 can also control the combined selection of multiple exit ports 23. Thus, when light is emitted from multiple exit ports 23 corresponding to the same selector 22, the detector 24 receives multiple beams of light, which is equivalent to modulating the light, enhancing its intensity, and thus improving detection accuracy. Simultaneously, all exit ports 23 are arranged in an array on the blood glucose and blood oxygen multi-parameter detection chip 2, enabling the chip to achieve area array detection, which is equivalent to obtaining an array-type high-precision, high-stability adjustable light source.

[0046] Furthermore, when the selector 22 selects the output port 23, light sources 1 of different wavelengths can be turned on separately to select light to enter the blood glucose and blood oxygen multi-parameter detection chip 2 from different couplers 22, thereby realizing multi-parameter measurement. At this time, only light of the same wavelength enters the blood glucose and blood oxygen multi-parameter detection chip 2 at the same time, and after being selected by the selector 22 to the corresponding output port 23, it is emitted from this output port 23.

[0047] In addition to selecting the exit port 23, the gate selector 22 can also select light. For example, by controlling the gate selector 22, light transmitted from different couplers 21 can pass through the gate selector 22 to select the light from the corresponding light source 1. At this time, light sources 1 of different wavelengths can be turned on simultaneously, and light from multiple light sources 1 can enter different couplers 21 at the same time. However, due to the control of the gate selector 22, only the selected light can pass through the gate selector 22 and exit from the corresponding exit port 23. Unselected light, although it reaches the gate selector 22 through the coupler 21, cannot pass through the corresponding gate selector 22 and therefore cannot exit from the exit port 23. This also enables selective detection.

[0048] After being selected by the selector 22, the light is emitted from the exit port 23. After reaching the detection object, the light undergoes reflection and transmission before being received by the detector 24. As shown in Figure 1, all the exit ports 23 are evenly distributed around the circumference of one detector 24. In this embodiment, the detector 24 is integrated onto the blood glucose and blood oxygen multi-parameter detection chip 2; in other embodiments, the detector 24 may be separately disposed from the blood glucose and blood oxygen multi-parameter detection chip 2.

[0049] Furthermore, the exit port 23, coupler 21, and selector 22 are interconnected via waveguide 25. For example, the selector 22 and the exit port 23 can be connected via waveguide 25 (only a portion of the waveguide is shown in the figure; in actual use, the waveguide 25 can extend to and connect to the output port of the selector 22). In this embodiment, the three selectors 22 control a total of 12 exit ports 23. When these exit ports 23 are arranged in an array, there may be instances where the waveguides 25 of multiple exit ports 23 intersect. In this case, the intersections of different waveguides 25 are connected by intersecting waveguides or by passing through different layers, so that light passing through the intersections of waveguides 25 can still propagate along the set path and will not be guided into other waveguides 25.

[0050] In addition, the coupler 21, selector 22, outlet 23, detector 24, and waveguide 25 are provided on the blood glucose and blood oxygen multi-parameter detection chip 2 of this application, which can be regarded as the above-mentioned devices being fabricated on the substrate of the blood glucose and blood oxygen multi-parameter detection chip 2 by semiconductor process; wherein, the coupler 21, selector 22, outlet 23, and waveguide 25 are all formed by etching on the substrate.

[0051] The substrate of the blood glucose and oxygenation multi-parameter detection chip 2 can be made of nitride materials, and the materials that combine with nitrogen in the nitride materials include at least group III or group V chemical elements. Nitrides are one of the most representative third-generation semiconductor materials with a large band gap, allowing the blood glucose and oxygenation multi-parameter detection chip 2 to cover light wavelengths between 400nm and 2500nm. This means the blood glucose and oxygenation multi-parameter detection chip 2 can cover the visible to near-infrared bands, enabling multi-parameter measurement across different wavelengths. In this embodiment, the coupler 21, the selector 22, the output port 23, and the waveguide 25 that enables the optical connection between the coupler 21, the selector 22, and the output port 23 are made of nitrides. The nitrides used here are common semiconductor nitride materials such as silicon nitride, germanium nitride, and gallium nitride, and may also include group III or group V nitride materials.

[0052] The material of detector 24 is different from the material of the substrate of blood glucose and blood oxygen multi-parameter detection chip 2. Detector 24 may be a variety of detectors. For different wavelengths, the material of detector 24 may be silicon, group III and V materials in the periodic table of chemical elements, etc. The specific selection and setting can be made according to actual needs.

[0053] One coupler 21 can correspond to one selector 22, and one coupler 21 can also correspond to multiple selectors 22 at the same time. By superimposing the array of selectors 22, more outlets 23 can be corresponding to the array, so that the area array detection range formed on the blood glucose and blood oxygen multi-parameter detection chip 2 is expanded to a wider extent, which is more conducive to improving the detection accuracy.

[0054] For ease of understanding, specific embodiments are described below;

[0055] Coupler 211 is optically connected to selector 221, which is correspondingly connected to exit ports 2311, 2312, 2313, and 2314. By controlling selector 221, exit ports 2311, 2312, 2313, and 2314 can be selected simultaneously, or three, two, or even just one exit port can be selected. In this way, light of the first wavelength corresponding to light source 11 enters the blood glucose and blood oxygen multi-parameter detection chip 2 through coupler 211, and light can be emitted through the selected exit port 23 by controlling selector 221 and received by detector 24.

[0056] Similarly, coupler 212 is optically connected to selector 222, which is correspondingly connected to exit ports 2321, 2322, 2323, and 2324. By controlling selector 222, exit ports 2321, 2322, 2323, and 2324 can be selected simultaneously, or three, two, or even only one exit port can be selected. In this way, the second wavelength light corresponding to light source 12 enters the blood glucose and blood oxygen multi-parameter detection chip 2 through coupler 212, and the light can be emitted through the selected exit port 23 and received by detector 24 by controlling selector 222.

[0057] For coupler 213, coupler 213 is optically connected to selector 223, which is correspondingly connected to exit ports 2331, 2332, 2333, and 2334. By controlling selector 223, exit ports 2331, 2332, 2333, and 2334 can be selected simultaneously, or three, two, or even only one exit port 23 can be selected. In this way, the light of the third wavelength corresponding to light source 13 enters the blood glucose and blood oxygen multi-parameter detection chip 2 through coupler 213, and the light can be emitted through the selected exit port 23 and received by detector 24 by controlling selector 223.

[0058] Couplers 211, 212, and 213 are used to couple three different wavelengths of light respectively. Then, selectors 221, 222, and 223 are used to select different exit ports 23 to precisely control the light emitted from each exit port. Furthermore, by controlling the light emitted from multiple exit ports 23 corresponding to the same selector 22, combined selection of multiple exit ports 23 can be achieved. This strengthens the intensity of the emitted light, correspondingly strengthening the light signal received by the detector 24, thereby improving detection accuracy.

[0059] As mentioned above, in addition to selecting the exit port 23, the selector 22 can also select the incident light. Taking Figure 1 as an example, light sources 11, 12, and 13 can also be turned on simultaneously. The light from light sources 11, 12, and 13 enters the blood glucose and blood oxygen multi-parameter detection chip 2 simultaneously through couplers 211, 212, and 213, respectively. Assuming that only selector 221 is turned on at this time, the light corresponding to light source 11 passes through coupler 211 and then through selector 221, and is selected and emitted through the corresponding exit port 23. When selectors 222 and 223 are not turned on, the light from light sources 12 and 13 enters the blood glucose and blood oxygen multi-parameter detection chip 2, but cannot pass through selectors 222 and 223, and therefore cannot be emitted from the corresponding exit port 23. This achieves light selection, which can be applied to scenarios where multiple light sources 1 are turned on simultaneously.

[0060] Based on this, the multiple outlets 23 corresponding to different selectors 22 can be distributed alternately. In this way, for the same selector 2, the multiple outlets 23 corresponding to it can be evenly distributed on the blood glucose and blood oxygen multi-parameter detection chip 2, avoiding excessive concentration of multiple outlets 23 in the same group, which would lead to missed detections in some areas and cause detection deviations. For example, in Figure 3, the outlets 2311, 2312, 2313, and 2314 corresponding to selector 221 are arranged alternately, and the outlets 2321, 2322, 2323, and 2324 corresponding to selector 222, and the outlets 2331, 2332, 2333, and 2334 corresponding to selector 223 are alternately set at the intervals.

[0061] In the above embodiment, only one detector 24 is set, and all the emission ports 23 are arranged in a ring around the detector 24. The light emitted from all the emission ports 23 is received by this detector 24.

[0062] The embodiment shown in Figure 2 of this application also provides a multi-parameter blood glucose and blood oxygen detection chip 2. Unlike the previous embodiment, this multi-parameter blood glucose and blood oxygen detection chip 2 has multiple detectors 24. The multiple detectors 24 are arranged in a rectangular array, and emission ports 23 are distributed around the multiple detectors 24. Here, there are four detectors 24, namely a first detector 241, a second detector 242, a third detector 243, and a fourth detector 244. All emission ports 23 are arranged in a rectangular array around these four detectors 24, and the light emitted from all emission ports 23 to the detection target is ultimately received by these four detectors 24.

[0063] There are multiple light sources 1, multiple selectors 22, and multiple detectors 24. Different light sources 1 emit light of different wavelengths. Each light source 1 is connected to the input terminal 22a of a selector 22 via a coupler 21. Multiple output terminals 22b of the same selector 22 are arranged around the same detector 24. The light emitted by one of the multiple light sources 1 passes through the coupler 21 to the corresponding selector 22. The selector 22 controls the light transmitted from the coupler 21 to be emitted from the corresponding output port 23. The detector 24 receives the light emitted from the output ports 23 around itself and the light transmitted back after reflection or transmission.

[0064] Alternatively, multiple output terminals 22b of the same selector 22 are respectively set next to different detectors 24. The light emitted by one of the multiple light sources 1 reaches the corresponding selector 22 through the coupler 21. The selector 22 controls the light transmitted from the coupler 21 to be emitted from the corresponding output port 23. Multiple detectors 24 jointly receive the light emitted from the output port 23 around them and the light transmitted back after reflection or transmission.

[0065] Specifically, the coupler 211 is optically connected to the selector 221, and the selector 221 is connected to nine output ports 23, namely output port 2331, output port 2332, output port 2333..., output port 2339.

[0066] Coupler 212 is optically connected to selector 222. Selector 222 is connected to nine outlets 23, namely 2311, outlet 2312, outlet 2313, ..., outlet 2319.

[0067] Coupler 213 is optically connected to selector 223. Selector 223 is connected to nine output ports 23, namely 2321, output port 2322, output port 2323, ..., output port 2329.

[0068] Taking outlets 2331, 2332, 2333, ..., 2339 as examples, in this embodiment, outlets 2331, 2332, 2333, ..., 2339 are arranged in a rectangular array, and these nine outlets 23 are evenly distributed around the first detector 241, the second detector 242, the third detector 243, and the fourth detector 244; in other embodiments, these nine outlets 23 may also be arranged around any one of the detectors 24, or around any two or any three detectors 24.

[0069] During operation, light of the same wavelength can be emitted from some of the nine emission ports 23, or from all of the nine emission ports 23. The more emission ports 23 that can emit light, the stronger the light intensity and the higher the detection accuracy.

[0070] The gating of light and the gating of the exit port 23 in Figure 2 can be referred to Figure 1, and will not be repeated here.

[0071] The above embodiments show different numbers and array arrangements of the selector 22, the outlet 23, and the detector 24. In other embodiments, the selector 22, the outlet 23, and the detector 24 can also be presented in other numbers or other arrangements. The specific arrangements can be set according to actual needs, and this application does not impose any restrictions on them.

[0072] In summary, the blood glucose and oxygenation multi-parameter detection chip 2 of this application can receive incident light from light sources 1 of different wavelengths. The chip covers the entire wavelength range from visible to near-infrared, enabling multi-wavelength and multi-parameter measurements. The control selector 22 selects different wavelengths of light from different exit ports 23, allowing the selected light to exit through the corresponding exit port 23. Different exit ports 23 can also be combined for selection, achieving light modulation and improving detection accuracy. The exit ports 23 of the blood glucose and oxygenation multi-parameter detection chip 2 adopt an array layout, transforming traditional single-point detection into area array detection, which greatly improves detection accuracy and convenience. This blood glucose and oxygenation multi-parameter detection chip 2 is manufactured using existing CMOS technology, resulting in high integration, low cost, and excellent waveguide performance. In summary, this application, through the integrated blood glucose and blood oxygen multi-parameter detection chip 2 and its arrayed layout, enables smart wearable devices made using the blood glucose and blood oxygen multi-parameter detection chip 2 of this application to have advantages such as compact structure, low power consumption, high accuracy, and the ability to perform multi-parameter measurements, thereby meeting the needs of health monitoring and improving user experience.

[0073] Please refer to Figure 3, which illustrates a wearable device provided in one embodiment of this application. The wearable device may include a smartwatch, smart bracelet, etc. The wearable device is worn on the object being tested, 4. The wearable device includes the aforementioned multi-parameter blood glucose and oxygenation detection chip 2 and processing system 3. In this embodiment, the light source 1, detector 24, and other components in the multi-parameter blood glucose and oxygenation detection chip belong to different chips and are made of different materials. The light source 1 includes multiple light sources arranged in a side-by-side array. The multi-parameter blood glucose and oxygenation detection chip 2 is located on the light-emitting side of the multiple light sources 1. The light source 1 and detector 24 are located on the same side of the object being tested, and detector 24 is disposed on the multi-parameter blood glucose and oxygenation detection chip 2. The processing system 3 is electrically connected to the multiple light sources 1, the selector 22 of the multi-parameter blood glucose and oxygenation detection chip 2, and detector 24, respectively.

[0074] The light emitted from the light source 1 enters the blood glucose and blood oxygen multi-parameter detection chip 2, and is emitted to the detection object 4 through the selected emission port 23 on the blood glucose and blood oxygen multi-parameter detection chip 2. The light is then reflected or transmitted to the detector 24 by the detection object 4. The detector 24 feeds back the received signal to the processing system 3. The processing system 3 amplifies, filters, extracts and processes the signal received by the detector 24 to obtain measurement data of different wavelengths, thereby completing the multi-parameter measurement of the detection object 4.

[0075] The light source 1 may include a laser diode or a vertical cavity surface-emitting laser, and the wavelength of the light source 1 is generally between 400nm and 2500nm.

[0076] The processing system 3 may include a microprocessor unit and its supporting circuits. The MCU chip controls the operation of the entire detection project (such as a non-invasive blood glucose meter). The processing system 3 can directly control the on and off of the light source 1. It can also control the selector 22 on the blood glucose and blood oxygen multi-parameter detection chip 2 to achieve light selection, so that the selected light passes through the selector 22 and is emitted from the outlet 23 to irradiate the human tissue (detection object 4).

[0077] There can be one or more detectors 24, arranged according to different needs. Detector 24 can be a low dark current, large target area photodetector to detect light reflected back from human tissue.

[0078] In this embodiment, there are multiple detectors 24, and the multiple detectors 24 are integrated with the blood glucose and blood oxygen multi-parameter detection chip 2. At this time, the detectors 24 can be set in two ways: one is to integrate them into the blood glucose and blood oxygen multi-parameter detection chip 2, and the other is to bond them to the blood glucose and blood oxygen multi-parameter detection chip 2. Those skilled in the art can choose the setting according to actual needs.

[0079] The fourth type of test subject is generally human tissue or parts of the human body that need to be tested, such as the wrist, fingers, base of the thumb, earlobe, and arm.

[0080] Referring to Figure 4, in this embodiment, the detector 24 can be set separately outside the blood glucose and blood oxygen multi-parameter detection chip 2. In this way, the detector 24 does not occupy the space on the blood glucose and blood oxygen multi-parameter detection chip 2, which can reduce the size of the blood glucose and blood oxygen multi-parameter detection chip 2.

[0081] In summary, the wearable device provided in this application embodiment utilizes the blood glucose and blood oxygen multi-parameter detection chip 2, which can transform the currently common single-parameter detection into multi-parameter detection, achieving high detection accuracy. It also boasts advantages such as excellent performance, compact size, and low production cost. The wearable device provided in this application embodiment can provide multi-parameter health monitoring in daily life without interfering with the normal life of the monitored individual, thus meeting daily monitoring needs.

[0082] The above description is merely an embodiment of this application and is not intended to limit the scope of protection of this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the scope of protection of this application.

Claims

1. A multi-parameter detection chip for blood glucose and blood oxygen, characterized in that, include: A coupler, a gate, and multiple output ports are sequentially optically connected and integrated together, along with a light source and detector capable of emitting light of different wavelengths; The coupler is used to couple light of different wavelengths emitted from the light source to the selector. The selector selects light of different wavelengths to enter the corresponding emission port so that it can be emitted out through the emission port. The detector is used to receive the light that returns after being reflected or transmitted through the emission port.

2. The blood glucose and blood oxygen multi-parameter detection chip according to claim 1, characterized in that, There are multiple light sources and multiple gating devices. Different light sources emit light of different wavelengths. Each gating device includes an input terminal and multiple output terminals. Each light source is connected to the input terminal of a gating device through a coupler. The multiple output terminals of the gating device are respectively connected to different emission ports. The gating device controls whether the light emitted by the light source is emitted from the emission port.

3. The blood glucose and blood oxygen multi-parameter detection chip according to claim 2, characterized in that, The multiple emission ports are arranged in a ring around the detector.

4. The blood glucose and blood oxygen multi-parameter detection chip according to claim 1, characterized in that, The detectors are multiple, arranged in a rectangular array, and the emission ports are distributed around the multiple detectors.

5. The blood glucose and blood oxygen multi-parameter detection chip according to claim 4, characterized in that, The number of light sources, gating devices, and detectors are all multiple. Different light sources emit light of different wavelengths. Each gating device includes one input terminal and multiple output terminals. Each of the light sources is connected to the input of one of the gates via the coupler, and multiple outputs of the same gate are arranged around the same detector; Light emitted from one of the plurality of light sources passes through the coupler to the corresponding gate, which controls the light transmitted from the coupler to exit from the corresponding outlet. The detector receives the light emitted from the outlet around itself and transmitted back after reflection or transmission.

6. The blood glucose and blood oxygen multi-parameter detection chip according to claim 4, characterized in that, The number of light sources, gating devices, and detectors are all multiple. Different light sources emit light of different wavelengths. Each gating device includes one input terminal and multiple output terminals. Each of the light sources is connected to the input of a gate via the coupler, and multiple outputs of the same gate are respectively located next to different detectors; Light emitted from one of the multiple light sources passes through the coupler to the corresponding gate, which controls the light transmitted from the coupler to exit from the corresponding outlet. Multiple detectors collectively receive the light emitted from the outlets around them and transmitted back after reflection or transmission.

7. The blood glucose and blood oxygen multi-parameter detection chip according to any one of claims 1 to 6, characterized in that, The coupler, the gate, the output port, and the waveguide are fabricated on the substrate of the blood glucose and blood oxygen multi-parameter detection chip using semiconductor technology. The substrate is made of nitride material.

8. The blood glucose and blood oxygen multi-parameter detection chip according to claim 7, characterized in that, The nitride materials include silicon nitride, germanium nitride, gallium nitride, and group III or group V nitride materials.

9. The blood glucose and blood oxygen multi-parameter detection chip according to claim 8, characterized in that, The coupler is an end-face coupler or a grating coupler, and the light source is positioned near the coupler.

10. The blood glucose and blood oxygen multi-parameter detection chip according to claim 9, characterized in that, The wavelength range of the light emitted by the light source of the blood glucose and blood oxygen multi-parameter detection chip is 400nm to 2500nm.

11. The blood glucose and blood oxygen multi-parameter detection chip according to claim 10, characterized in that, The emission port is a grating-shaped emission port.

12. A wearable device, worn on a detection object, characterized in that, The invention includes a multi-parameter blood glucose and oxygenation detection chip and a processing system as described in any one of claims 1 to 11, wherein the multi-parameter blood glucose and oxygenation detection chip is located on the light-emitting side of the light source; and the processing system is electrically connected to a plurality of the light sources, the selector, and the detector, respectively. The light emitted from the light source is emitted to the object being detected through the emission port, and then reflected or transmitted by the object to the detector. The signal received by the detector is processed by the processing system to obtain detection data of different wavelengths, and finally, multi-parameter data of the object being detected is obtained.

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