Support frame, beam shaper, and neutron capture therapy system

Abstract

Provided in the present invention are a support frame, a beam shaper, and a neutron capture therapy system. The support frame of the present invention comprises an outer wall and a partition unit provided on the inner side of the outer wall; the partition unit is provided with at least one first fixing hole; and the at least one first fixing hole can be used for connecting to an assistant device. By means of the present technical solution, an operator can flexibly select suitable mounting points on the basis of assistant devices to be actually mounted, so that the assistant devices can be mounted without depending on additional connection structures, but instead can be directly connected to the support frame via the first fixing hole, thereby effectively reducing the treatment space occupied by connection structures while improving the conveniences in mounting and fixing the assistant devices, and furthermore, effectively solving the problems in the prior art that assistant devices for cooperating in neutron capture therapy are inconvenient to mount and fix and are prone to interference in therapy.

Description

Support frame, beam shaper and neutron capture therapy system TECHNICAL FIELD

[0001] The present application relates to the field of neutron capture therapy system, and specifically provides a support frame, a beam shaper and a neutron capture therapy system. BACKGROUND

[0002] With the development of atomic science, radiotherapy such as cobalt-60, linear accelerator, electron beam, etc. has become one of the main means of cancer treatment. However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself, which not only kills tumor cells but also causes damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, the treatment effect of traditional radiotherapy on malignant tumors with high radiation resistance (such as glioblastoma multiforme and melanoma) is often poor.

[0003] In order to reduce the radiation damage to the normal tissues around the tumor, the concept of targeted therapy in chemotherapy is applied to radiotherapy; and for tumor cells with high radiation resistance, radiation sources with high relative biological effectiveness (RBE) are actively developed, such as proton therapy, heavy particle therapy, and neutron capture therapy. Among them, neutron capture therapy combines the above two concepts, such as boron neutron capture therapy, which provides a better choice for cancer treatment than traditional radiation by specific accumulation of boron-containing drugs in tumor cells and precise neutron beam regulation. SUMMARY

[0004] During the neutron capture therapy, in the process of treatment planning or irradiation treatment, considering the treatment site of the patient, the irradiation dose, the state of the patient during irradiation, and the dose monitoring, etc., different auxiliary devices need to be equipped on or near the beam shaper to meet the different treatment needs of patient positioning, monitoring and detection, etc., so as to ensure reasonable irradiation dose and safe irradiation environment.

[0005] However, the existing auxiliary devices still need to be additionally equipped with connecting or fixing devices when installed on or near the beam shaper, which not only makes it inconvenient to install and fix the auxiliary devices, but also causes the problem of treatment interference, so that it is difficult to ensure reasonable irradiation dose.

[0006] In order to solve the problems that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also is easy to cause therapy interference, the application provides a support frame. The support frame of the application comprises an outer wall and a partition unit arranged inside the outer wall, and the partition unit is provided with at least one first fixing hole which can be used for connecting with the auxiliary device.

[0007] The support frame of the application can be used to provide a stable installation position for components such as neutron shielding bodies and reflecting bodies in a beam shaping body. The support frame comprises an outer wall and a partition unit arranged inside the outer wall, so that the space surrounded by the outer wall can be reasonably planned by the partition unit. The partition unit is provided with at least one first fixing hole which can be used for connecting with the auxiliary device. The auxiliary device is directly connected with the support frame which plays a major supporting role in the beam shaping body, so that stable support can be ensured when the auxiliary device is arranged on the beam shaping body. The first fixing hole provided on the partition unit provides more installation positions for the auxiliary device, and the operator can flexibly select appropriate point positions for installation according to the actually installed auxiliary device. Therefore, through the above arrangement, the installation of the auxiliary device no longer depends on additional connecting structures, but can be directly connected with the support frame through the first fixing hole, thereby improving the convenience of installation and fixation of the auxiliary device, and effectively reducing the occupation of the connecting structure to the treatment space, thereby effectively solving the problems that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also is easy to cause therapy interference.

[0008] In the preferred technical solution of the above support frame, a beam through hole is arranged at the center of the support frame, and the first fixing holes are radially arranged around the beam through hole. Through the above arrangement, the beam through hole is used for passing the neutron beam, and the first fixing holes are radially arranged around the beam through hole to facilitate the installation of the auxiliary device around the patient irradiated by the beam.

[0009] In the preferred technical solution of the above support frame, the partition unit comprises a plurality of radial walls which are arranged around the beam through hole in a spaced manner, each of the radial walls extends along the radial direction of the beam through hole, and at least one of the first fixing holes is arranged on the radial wall. Through the above arrangement, the plurality of radial walls arranged around the beam through hole in the axial direction provide setting positions for the first fixing holes from multiple directions, so as to provide fixing point positions for the auxiliary device from multiple directions, so that various types of auxiliary devices can be connected with the support frame through the first fixing holes, so that the application has a wider application scenario.

[0010] In the preferred technical solution of the support frame, the radial wall is arranged in a "cross" shape. Through the above arrangement, the radial wall is evenly arranged around the beam hole, so as to provide fixing points for the auxiliary device from 8 directions, and various types of auxiliary devices can be connected to the support frame through the first fixing hole.

[0011] In the preferred technical solution of the support frame, the partition unit comprises a plurality of circumferential walls around the beam hole, adjacent circumferential walls are spaced apart along the radial direction of the beam hole, and at least one first fixing hole is arranged on the circumferential wall. Through the above arrangement, the first fixing hole can be used for the auxiliary device arranged around the beam outlet.

[0012] In the preferred technical solution of the support frame, the partition unit comprises a plurality of partition walls, and the first fixing hole is arranged at the intersection of two partition walls. Through the above arrangement, the first fixing hole is arranged at the intersection of two partition walls, which can make full use of the material at the intersection, and can reduce the influence of the first fixing hole on the structural strength of the support frame as much as possible.

[0013] In the preferred technical solution of the support frame, the outer wall is arranged in a square frame-shaped member. Through the above arrangement, the square frame-shaped outer wall can be more conveniently fixed in the treatment room, and one side of the square frame can be connected to the bottom surface or other suitable base.

[0014] In the preferred technical solution of the support frame, the partition unit further comprises a reinforcing part, and two ends of the reinforcing part are connected to adjacent two sides of the square frame-shaped member. Through the above arrangement, the reinforcing part further improves the stability of the support frame, so as to reliably support the components such as the moderator, neutron shielding body or reflector arranged in the support frame, and to stably fix the auxiliary device on the support frame.

[0015] In the preferred technical solution of the support frame, the connection between the reinforcing part and the outer wall is provided with a first fixing hole. Arranging the first fixing hole at the connection between the reinforcing part and the outer wall can make full use of the material at the connection, and can reduce the influence of the first fixing hole on the structural strength of the support frame as much as possible.

[0016] In the preferred technical solution of the support frame, in addition to the first fixing hole for connecting the auxiliary device, the support frame can be connected to the cover plate assembly through the remaining first fixing holes. The beam shaping body is usually provided with a cover plate assembly for preventing the components such as the neutron shielding body and the reflector from falling off the support frame. Through the above arrangement, the cover plate assembly can be further reinforced and connected to the support frame through the first fixing hole, or the connection mode of the first fixing hole is adopted to replace the existing connection mode between the support frame and the cover plate assembly.

[0017] In order to solve the problem that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also easy to cause treatment interference, the present application further provides a beam shaping body. The beam shaping body of the present application comprises a support frame and a cover plate assembly arranged on one side of the support frame, wherein the support frame comprises an outer wall and a partition unit arranged on the inner side of the outer wall, and at least one first fixing hole is arranged on the side of the partition unit facing the cover plate assembly, and the at least one first fixing hole can be used for connecting with the auxiliary device. Through the arrangement of the support frame, the installation of the auxiliary device no longer depends on the additional connecting structure, but can be directly connected with the support frame through the first fixing hole, thereby improving the installation efficiency and connection stability of the auxiliary device, and reducing the occupation of the treatment space of the patient by the connecting structure, thereby improving the installation and fixing convenience of the auxiliary device while reducing the occupation of the treatment space by the connecting structure, and effectively solving the problem that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also easy to cause treatment interference.

[0018] In the preferred technical solution of the above beam shaping body, a beam through hole is arranged in the center of the support frame, and the first fixing holes are arranged radially around the beam through hole. Through the above arrangement, the beam through hole is used for passing the neutron beam, and the first fixing holes are arranged radially around the beam through hole to facilitate the installation of the auxiliary device around the patient irradiated by the beam.

[0019] In the preferred technical solution of the above beam shaping body, the cover plate assembly comprises a second fixing hole, and the first fixing hole and the corresponding second fixing hole are used for connecting with the auxiliary device. Through the above arrangement, the cover plate assembly can effectively prevent the components such as neutron shielding body and reflector from falling off the support frame.

[0020] In the preferred technical solution of the above beam shaping body, the auxiliary device and the support frame are connected through the first fixing hole, and the support frame and the cover plate assembly are connected through the first fixing hole and the second fixing hole. Through the above arrangement, in addition to the first fixing hole and the second fixing hole used for connecting with the auxiliary device, the cover plate assembly can be connected with the support frame through the remaining first fixing hole and the corresponding second fixing hole, so that the auxiliary device and the support frame can be conveniently connected with the support frame through the fastener extending through the second fixing hole and the first fixing hole.

[0021] In the preferred technical scheme of the beam shaping body, the cover plate assembly comprises a neutron shielding layer baffle, a reflector baffle and a front baffle in sequence away from the support frame, and the second fixing hole extends from the front baffle to the neutron shielding layer baffle. Through the above arrangement, neutrons are effectively blocked on the side facing the patient, so that neutrons can only irradiate the treatment site of the patient from the beam through hole, and cannot leak from other positions of the beam shaping body, thereby improving the safety of the device.

[0022] In the preferred technical scheme of the beam shaping body, the reflector baffle is provided with a mounting groove for accommodating the connecting structure of the beam collimating device. Through the arrangement of the mounting groove, the beam collimating device matched with the beam shaping body can be installed on the side of the front baffle facing the patient, and the connecting structure is accommodated in the mounting groove, which ensures the connection reliability of the beam collimating device and reduces the occupation of the treatment space of the patient by the beam collimating device, thereby further avoiding the problem of treatment interference.

[0023] In order to solve the problem that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also easy to cause treatment interference, the present application further provides a neutron capture therapy system. The neutron capture therapy system of the present application comprises a beam shaping body and an auxiliary device, the beam shaping body comprises a support frame, wherein the support frame comprises an outer wall and a partition unit arranged on the inner side of the outer wall, at least one first fixing hole is arranged on the partition unit, and the auxiliary device is connected with the support frame through the at least one first fixing hole. Through the above arrangement, the installation of the auxiliary device no longer depends on the additional connecting structure, but can be directly connected with the support frame through the first fixing hole, thereby improving the installation efficiency and connection stability of the auxiliary device, reducing the occupation of the treatment space of the patient by the connecting structure, improving the space utilization of the device, and effectively solving the problem that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also easy to cause treatment interference.

[0024] In the preferred technical scheme of the neutron capture therapy system, the support frame is provided with a beam through hole at the center, and the first fixing holes are arranged radially around the beam through hole.

[0025] In the preferred technical scheme of the above neutron capture therapy system, the auxiliary device comprises a beam collimation device, a patient positioning device and a monitoring and detecting device. Through the arrangement of the beam collimation device, the part of the patient to be treated can accurately receive the irradiation of the neutron beam with appropriate intensity. Through the arrangement of the patient positioning device, the movement of the patient during the treatment is limited, preventing the part to be treated from deviating and damaging the normal tissue. Through the arrangement of the monitoring and detecting device, the body posture, position and vital signs of the patient, the beam intensity and irradiation position of the equipment, and the radiation intensity, temperature and other parameters in the treatment environment can be detected, so as to provide accurate treatment for the patient. BRIEF DESCRIPTION OF DRAWINGS

[0026] The preferred embodiments of the present application will be described below in conjunction with the accompanying drawings, in which:

[0027] Fig. 1 is a structural schematic diagram of an embodiment of the support frame of the present application;

[0028] Fig. 2 is an exploded view of an embodiment of the beam shaping body of the present application;

[0029] Fig. 3 is a structural schematic diagram of an embodiment of the neutron capture therapy system of the present application;

[0030] Fig. 4 is a structural schematic diagram of a first embodiment of the neutron capture therapy system of the present application installed with an auxiliary device;

[0031] Fig. 5 is a structural schematic diagram of a second embodiment of the neutron capture therapy system of the present application installed with an auxiliary device;

[0032] Fig. 6 is a structural schematic diagram of a third embodiment of the neutron capture therapy system of the present application installed with an auxiliary device;

[0033] Fig. 7 is a structural schematic diagram of a fourth embodiment of the neutron capture therapy system of the present application installed with an auxiliary device;

[0034] Fig. 8 is an exploded view of part of the fourth embodiment of the neutron capture therapy system of the present application installed with an auxiliary device shown in Fig. 7.

[0035] List of reference signs: 1, neutron capture therapy system; 100, beam shaping body; 10, support frame; 11, outer wall; 111, front opening; 12, partition unit; 121, first fixing hole; 1211, first direction; 1212, second direction; 122, partition wall; 123, radial wall; 124, circumferential wall; 125, reinforcing part; 13, transverse wall; 14, vertical wall; 15, beam through hole; 20, cover plate assembly; 21, second fixing hole; 22, neutron shielding layer baffle; 23, reflector baffle; 231, mounting groove; 24, front baffle; 300, auxiliary device; 310, beam collimation device; 320, patient positioning device; 321, thermoplastic film; 3211, thermoplastic head film; 3212, thermoplastic body film; 322, head support; 330, monitoring and detection device; 331, patient positioning detection device; 3311, mounting part; 3312, scale; 3313, laser device; 332, beam detection device; 3321, support; 3322, detection module; 400, accelerator; 500, neutron generating part. DETAILED DESCRIPTION

[0036] The preferred embodiments of the present application will be described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are only used to explain the technical principles of the present application, and are not intended to limit the protection scope of the present application.

[0037] It should be noted that in the description of the present application, the terms "first", "second" are only for the purpose of description, and cannot be understood as indicating or implying relative importance.

[0038] In addition, it should also be noted that in the description of the present application, unless otherwise explicitly specified and limited, the terms "set", "connected" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be directly connected, or indirectly connected through an intermediate medium, or the internal communication of two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0039] Neutron capture therapy as an effective means of treating cancer in recent years gradually increased, which is the most common boron neutron capture therapy, boron neutron capture therapy can be supplied by nuclear reactors or accelerators. The embodiments of the present application take the accelerator boron neutron capture therapy as an example, the basic components of the accelerator boron neutron capture therapy usually include an accelerator for accelerating charged particles (such as protons, deuterons, etc.), a neutron capture therapy system, wherein the neutron capture therapy system includes a target material, a heat removal system and a beam shaping body, wherein the accelerated charged particles interact with the target material to generate neutrons, and the appropriate nuclear reaction is selected according to the required neutron yield and energy, the available accelerated charged particle energy and current size, and the physical and chemical properties of the target material. The commonly discussed nuclear reactions are 7 Li(p,n) 7 Be and 9 Be(p,n) 9 B, both of which are endothermic reactions. The energy threshold of the two nuclear reactions is 1.881 MeV and 2.055 MeV, respectively. Since the ideal neutron source for boron neutron capture therapy is keV energy level superhot neutron, theoretically, if the protons with energy slightly higher than the threshold energy are used to bombard the lithium metal target, relatively low energy neutrons can be generated, which do not need too much slowing down treatment and can be used for clinical treatment. However, the interaction cross section of lithium metal (Li) and beryllium metal (Be) with protons at threshold energy is not high, so higher energy protons are usually selected to initiate nuclear reactions.

[0040] In order to solve the problem that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also easy to cause treatment interference, the present application provides a support frame, a beam shaping body and a neutron capture therapy system.

[0041] Fig. 1 is a structural schematic view of an embodiment of the support frame of the present application. As shown in Fig. 1, the support frame 10 of the present application comprises an outer wall 11 and a partition unit 12 arranged on the inner side of the outer wall 11. The partition unit 12 is provided with at least one first fixing hole 121. The at least one first fixing hole 121 can be used to connect with the auxiliary device 300 (shown in Fig. 4). The connection mode includes but is not limited to screwing, clamping and the like. The installation of the auxiliary device 300 no longer depends on additional connecting structures, but can be directly connected with the support frame 10 through the first fixing hole 121, thereby improving the installation efficiency and connection stability of the auxiliary device 300, reducing the occupation of the connecting structure to the treatment space of the patient, improving the space utilization of the equipment, and effectively solving the problem that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also easy to cause treatment interference.

[0042] Continuing to refer to FIG. 1, in some other embodiments, the separation unit 12 includes a plurality of partition walls 122, and a first fixing hole 121 is provided at the intersection of two partition walls 122. Stress concentration usually occurs at the intersection of the partition walls 122, and the material or structural strength at this point also needs to be designed higher. By utilizing the higher structural strength at the intersection, the auxiliary device 300 can be stably fixed to the support frame 10 through the first fixing hole 121. Alternatively, the first fixing hole 121 can also be provided at other suitable positions of the separation unit 12, such as in the middle section of any one of the partition walls 122.

[0043] Continuing to refer to FIG. 1, in some other embodiments, a beam through hole 15 is formed at the center of the support frame 10, that is, the separation unit 12 encloses the beam through hole 15. The beam through hole 15 allows a neutron beam to pass through. Additionally, a magnesium fluoride block can also be provided in the beam through hole 15 as a basic part of the moderator, and the moderator is used to slow down the neutrons generated from the target to the epithermal neutron energy region. The first fixing holes 121 are arranged radially around the beam through hole 15 at intervals. Exemplarily, as shown in FIG. 2, the first fixing holes 121 are arranged at intervals outward in 8 different directions centered on the beam through hole 15, and 4 first fixing holes 121 are provided in each direction, so as to facilitate the arrangement of the auxiliary device 300 near the neutron beam, thereby fixing the patient or detecting parameters, etc. Alternatively, the first fixing holes 121 can also be arranged with more than 8 or less than 8 arrangement directions, such as 4 or 6 arrangement directions, and the included angles between adjacent arrangement directions are equal. Alternatively, the number of the first fixing holes 121 in each arrangement direction can also be set differently, such as other numbers more than 4 or less than 4.

[0044] In some other embodiments, the separation unit 12 includes a plurality of radial walls 123 arranged at intervals in the circumferential direction of the beam through hole 15. Each radial wall 123 extends along the radial direction of the beam through hole 15. The space inside the outer wall 11 is divided into a plurality of fan-shaped regions by the radial walls 123, so as to install components including but not limited to moderators, reflectors, and neutron shields in sub-regions. Each radial wall 123 can be configured as a flat plate or as a bent plate. At least one first fixing hole 121 is provided on the radial wall 123, so that the plurality of first fixing holes 121 are arranged along the radial direction of the beam through hole 15. Further, the radial wall 123 can be configured as a "cross" shape, so that the space around the beam through hole 15 is evenly divided into a plurality of fan-shaped regions with equal included angles, so as to facilitate the accommodation of components such as moderators, reflectors, or neutron shields with the same specifications; also, the first fixing holes 121 are evenly distributed around the outside of the beam through hole 15, and the operator can find the installation position that best suits the patient currently receiving treatment among multiple different points to fix the auxiliary device 300 and assist the patient in treatment. Alternatively, the setting of the radial wall 123 can also be cancelled according to actual needs.

[0045] In some other embodiments, the partition unit 12 comprises a plurality of circumferential walls 124 surrounding the beam through hole 15. Adjacent circumferential walls 124 are spaced apart along the radial direction of the beam through hole 15, forming a plurality of concentric ring-like members. The space inside the outer wall 11 is divided into a plurality of annular regions by the circumferential walls 124, so as to install components including but not limited to a moderator, a reflector, and a neutron shielding body, etc. by region. For example, the moderator is installed in the inner annular region, the reflector is installed in the middle annular region, and the neutron shielding body is installed in the outer annular region. At least one first fixing hole 121 is arranged on the circumferential wall 124, so that the first fixing holes 121 can be arranged along the circumference of the beam through hole 15, to facilitate the installation of the auxiliary device 300 which needs to be arranged along the circumference of the beam through hole 15. In some other embodiments, the first fixing hole 121 is arranged at the intersection of the radial wall 123 and the circumferential wall 124. Alternatively, the circumferential wall 124 can also be omitted according to actual needs.

[0046] Continuing to refer to FIG. 2, in some other embodiments, the outer wall 11 is configured as a square frame-like member, and comprises two opposite horizontal walls 13 and two opposite vertical walls 14. The horizontal walls 13 can be configured to extend in the horizontal direction, and the vertical walls 14 are configured to extend in the vertical direction, so as to facilitate the embedding of the beam shaping body in the concrete wall of the treatment room. Alternatively, the horizontal walls 13 and the vertical walls 14 can also be configured to extend in other directions; the outer wall 11 can also be configured in other suitable shapes according to actual needs, to facilitate installation.

[0047] Continuing to refer to FIG. 1, in some other embodiments, the partition unit 12 further comprises a reinforcing portion 125. The two ends of the reinforcing portion 125 are connected to the adjacent two sides of the outer wall 11 configured as a square frame-like member, i.e. the two ends of the reinforcing portion 125 are connected to the adjacent horizontal wall 13 and vertical wall 14, and enclose a substantially triangular region, so as to enhance the stability of the support frame 10. In addition, components for preventing neutron leakage such as a neutron shielding body can also be arranged in the triangular region. Alternatively, the reinforcing portion 125 can also be connected to other suitable positions of the outer wall 11. In some other embodiments, the connection between the reinforcing portion 125 and the outer wall 11 is provided with a first fixing hole 121. The connection between the reinforcing portion 125 and the outer wall 11 is usually a stress concentration, and the material or structural strength at this position also needs to be designed to be higher. By utilizing the higher structural strength at the connection, the auxiliary device 300 can be stably fixed to the support frame 10 through the first fixing hole 121.

[0048] In some other embodiments, the outer wall 11 and the partition unit 12 can be fixedly connected in a manner including but not limited to screwing, riveting or one-piece forming, etc. Alternatively, the outer wall 11 and the partition unit 12 can be spaced apart from each other, so that the partition unit 12 only serves to separate the components such as reflectors and retarders inside the outer wall 11. The outer wall 11 and the partition unit 12 are made of aluminum alloy material. Alternatively, the outer wall 11 and the partition unit 12 can also be made of other materials with high strength, such as steel material, copper material, etc.

[0049] In some other embodiments, the auxiliary device 300 is connected to the support frame 10 through one or more first fixing holes 121, and the remaining first fixing holes 121 can be used to connect the support frame 10 and the cover plate assembly 20 (shown in FIG. 2) matched therewith.

[0050] FIG. 2 is an exploded view of an embodiment of the beam shaper of the present application. As shown in FIG. 2, the beam shaper 100 of the present application includes the support frame 10 described above and the cover plate assembly 20 arranged on one side of the support frame 10.

[0051] Continuing to refer to FIG. 2, in some other embodiments, the first fixing holes 121 are adapted to be arranged on the side of the partition unit 12 facing the cover plate assembly 20. The cover plate assembly 20 includes second fixing holes 21, and the cover plate assembly 20 and the support frame 10 are connected through the first fixing holes 121 and the second fixing holes 21. Further, at least one first fixing hole 121 corresponds to a second fixing hole 21, and the auxiliary device 300 and the support frame 10 can be connected through the first fixing hole 121 and the corresponding second fixing hole 21. Exemplarily, the fastener of the auxiliary device 300 extends through the second fixing hole 21 to be fixed together with the first fixing hole 121, so that the installation of the auxiliary device 300 no longer depends on additional connecting structures, but can be directly connected with the support frame 10 through the first fixing hole 121 and the second fixing hole 21, thereby improving the installation efficiency and connection stability of the auxiliary device 300, reducing the occupation of the treatment space of the patient by the connecting structure, improving the space utilization of the equipment, and effectively solving the problem that the auxiliary device for cooperating with the neutron capture therapy in the prior art is not only inconvenient to install and fix, but also easy to cause treatment interference.

[0052] In some other embodiments, the outer wall 11 includes a front opening 111, and the cover plate assembly 20 can cover the front opening 111 to prevent the components such as the moderator and the reflector arranged inside the support frame 10 from falling out. The auxiliary device 300 is connected to the support frame 10 through part of the first fixing holes 121 and the corresponding second fixing holes 21, and the remaining first fixing holes 121 and second fixing holes 21 can be used to connect the cover plate assembly 20 and the support frame 10, so as to fix the cover plate assembly 20 and the support frame 10. In alternative embodiments, other connection structures are provided between the cover plate assembly 20 and the support frame 10, for example, claws are arranged at the edges of the front opening 111, and when the cover plate assembly 20 covers the front opening 111, the claws are closed to clamp the cover plate assembly 20 to prevent it from falling out. Since part of the components arranged in the support frame 10 are made of heavy materials such as lead, reinforcing the connection between the cover plate assembly 20 and the support frame 10 through the first fixing holes 121 and the second fixing holes 21 can further improve the effect of the cover plate assembly 20 on preventing the components arranged inside the support frame 10 from falling out.

[0053] Referring to FIG. 2, in some other embodiments, the cover plate assembly 20 includes, in sequence away from the frame, a neutron shielding layer baffle 22, a reflector baffle 23, and a front baffle 24. The second fixing holes 21 extend through the neutron shielding layer baffle 22, the reflector baffle 23, and the front baffle 24. The neutron shielding layer baffle 22 is used to shield the leaked neutrons and photons to reduce the normal tissue dose in the non-irradiated area, and can be made of materials such as lead, boron carbide, and polyethylene. The reflector baffle 23 is used to guide the neutrons deviated from the central line direction of the beam hole 15 back to the central line direction to improve the intensity of the epithermal neutron beam, and can be made of materials such as lead and Teflon. The front baffle 24 can face the patient, can be made of materials such as lead and boron carbide, and can not only protect the reflector baffle 23 and the neutron shielding layer baffle 22, but also further reduce the intensity of the γ rays leaked from the front baffle 24. Alternatively, the cover plate assembly 20 can also include other suitable shielding plates or shielding materials.

[0054] FIG. 3 is a structural schematic diagram of an embodiment of the neutron capture therapy system of the present application. The present application also provides a neutron capture therapy system. The neutron capture therapy system of the present application includes the beam shaping body 100 and the auxiliary device 300, and the beam shaping body 100 includes the support frame 10 described above.

[0055] In some other embodiments, the auxiliary device 300 includes, but is not limited to, a beam collimation device 310, a patient positioning device 320, and a monitoring and detection device 330, and the following content will briefly describe part of the auxiliary device 300.

[0056] As shown in FIGS. 3 and 4, in some other embodiments, the auxiliary device 300 comprises a beam collimation device 310. The neutron capture therapy system 1 further comprises an accelerator 400 for generating a charged particle beam P and a neutron generating portion 500 for generating a neutron beam after irradiation by the charged particle beam P. The neutron generating portion 500 generates a neutron beam N after irradiation by the charged particle beam P, and the beam collimation device 310 concentrates the neutron generated by the neutron generating portion 500. In some other embodiments, the beam collimation device 310 can be connected to the support frame 10 through the first fixed holes 121 arranged along the circumference of the beam through hole 15 and the corresponding second fixed holes 21.

[0057] FIG. 4 is a structural schematic diagram of a first embodiment of the auxiliary device installed in the neutron capture therapy system of the present application, and FIG. 5 is a structural schematic diagram of a second embodiment of the auxiliary device installed in the neutron capture therapy system of the present application. As shown in FIGS. 4 and 5, the auxiliary device 300 further comprises a patient positioning device 320 for simulating the positioning of the patient before treatment or the positioning of the patient during treatment, i.e., positioning the optimal irradiation treatment position of the patient before and during treatment. The patient positioning device 320 includes, but is not limited to, a thermoplastic film 321, a headrest 322, etc. The thermoplastic film 321 comprises a thermoplastic head film 3211 and a thermoplastic body film 3212. The thermoplastic head film 3211 is fixedly connected with the beam collimation device 310, and can fix the head of the patient near the beam outlet of the beam collimation device 310, so as to treat the lesion of the patient's head. The thermoplastic body film 3212 is connected with the support frame 10 through the first fixed holes 121 and the corresponding second fixed holes 21. For example, based on the orientation shown in FIG. 5, the first fixed holes 121 and the second fixed holes 21 have 8 arrangement directions, and the adjacent arrangement directions have the same included angle. From the column above the vertical direction, along the clockwise direction, the 8 arrangement directions are respectively recorded as the first direction 1211, the second direction 1212,..., and the eighth direction. The thermoplastic body film 3212 has four fixed points, and is fixedly connected with the support frame 10 through the first fixed holes 121 in the third direction, the fourth direction, the sixth direction, and the seventh direction. In alternative embodiments, the thermoplastic film 321 can also be connected with the first fixed holes 121 in other suitable positions. As shown in FIG. 5, the headrest 322 is connected with the support frame 10 through the first fixed holes 121 in the eighth direction. In alternative embodiments, the thermoplastic film 321 and the headrest 322 can also be connected with the support frame 10 through the first fixed holes 121 in other suitable positions according to the actual shape of the product.

[0058] FIG. 6 is a structural schematic diagram of a third embodiment of the auxiliary device 300 installed in the neutron capture therapy system 1 according to the present application; FIG. 7 is a structural schematic diagram of a fourth embodiment of the auxiliary device 300 installed in the neutron capture therapy system 1 according to the present application. In some other embodiments, the auxiliary device 300 further comprises a monitoring and detecting device 330 for acquiring parameters during the neutron capture therapy. The parameters include, but are not limited to, the vital signs of the patient, the beam intensity of the device, the irradiation position, or the radiation intensity, temperature, etc. in the treatment environment, so as to provide precise treatment for the patient. The monitoring and detecting device 330 includes, but is not limited to, a patient positioning detecting device 331, a beam detecting device 332.

[0059] As shown in FIG. 6, the patient positioning detecting device 331 comprises a mounting portion 3311, a scale 3312 connected to the mounting portion 3311, and a laser device 3313 slidingly connected to the scale 3312. Based on the orientation shown in FIG. 5, the mounting portion 3311 can be connected to the support frame 10 through a plurality of first fixing holes 121 in the first direction 1211, the scale 3312 is configured to extend in the horizontal direction, and the laser device 3313 can emit cross laser towards the lower direction, so that the operator can adjust the patient’s position based on the cross laser as a reference, so that the treatment site of the patient is directly opposite to the beam outlet of the beam collimating device 310.

[0060] As shown in FIG. 7, the beam detecting device 332 comprises a bracket 3321 and a detection module 3322 slidingly connected to the bracket 3321. Based on the orientation shown in FIG. 5, the bracket 3321 is connected to the support frame 10 through at least four first fixing holes 121 and corresponding second fixing holes 21 in the directions. Exemplarily, the bracket 3321 can be connected to the support frame 10 through the first fixing holes 121 and the corresponding second fixing holes 21 in the second direction 1212, the fourth direction, the sixth direction and the eighth direction. Alternatively, the patient positioning detecting device 331 and the beam detecting device 332 can also be connected to the support frame 10 through other suitable first fixing holes 121 according to the actual shape of the product.

[0061] Figure 8 is a partial structure exploded view of a fourth embodiment of the neutron capture therapy system shown in Figure 7, in which the auxiliary device is installed. As shown in Figure 8, the neutron capture therapy system 1 includes an auxiliary device (e.g., beam detection device 332) and a support frame 10, and the auxiliary device is connected to the first fixing hole 121 on the support frame 10, so that it no longer relies on additional connecting structures, but can be directly connected to the support frame 10 that provides support for the beam shaping body 100, thereby improving the installation efficiency and connection stability of the auxiliary device. In some embodiments, a cover plate assembly 20 can be provided between the auxiliary device and the support frame 10 to prevent the deceleration body, the reflection body, and other components installed in the support frame 10 from falling off. Alternatively, the cover plate assembly 20 can also be provided in other suitable devices, as long as the device does not affect the connection of the auxiliary device to the first fixing hole 121 on the support frame 10.

[0062] The above embodiments are described for part of the auxiliary device 300, but in the actual application process of the neutron capture therapy system 1, due to the complexity of the patient's irradiation treatment site, it is necessary to generate individual corresponding irradiation treatment plans, and accordingly, medical personnel need to correspondingly set different auxiliary devices 300 on the beam shaping body 100 to achieve the irradiation intensity, quality or requirements that meet the irradiation treatment plan, such as a camera for monitoring the irradiation state during patient treatment or other devices for beam collimation, patient positioning, beam monitoring and detection, patient monitoring and detection, etc., which are not specifically limited here.

[0063] The operation method of the neutron capture therapy system in the present application will be described in detail below in combination with Figs. 4-7. After the operation method is started, step S1 is performed, i.e. the auxiliary device 300 is connected with the support frame 10 through at least one first fixing hole 121 and second fixing hole 21. Then step S2 is performed, i.e. the cover plate assembly 20 is connected with the support frame 10 through the remaining first fixing holes 121 and second fixing holes 21. The auxiliary device 300 is installed first so that the auxiliary device 300 can be fixed to the support frame 10 through the most suitable first fixing hole 121 without being affected by the fasteners of the cover plate assembly 20. When the auxiliary device 300 is fixed, the remaining first fixing holes 121 and second fixing holes 21 can be used to reinforce the connection between the cover plate assembly 20 and the support frame 10 so as to further improve the effect of the cover plate assembly 20 on preventing the components arranged inside the support frame 10 from falling out. It is worth noting that the above steps S1 and S2 can also be interchanged, i.e. the cover plate assembly 20 is connected with the support frame 10 through the first fixing holes 121 and second fixing holes 21 first, and then the auxiliary device 300 is connected with the support frame 10 through at least one first fixing hole 121 and second fixing hole 21. Or for some patients who do not need to install the auxiliary device, only the cover plate assembly 20 is connected with the support frame 10 through all the first fixing holes 121 and second fixing holes 21. For patients who need to install the auxiliary device, the auxiliary device can be quickly installed or fixed by removing the connecting bolts or other connecting components at appropriate positions of the first fixing holes 121 and second fixing holes 21.

[0064] Referring to Fig. 4, when the patient is treated, the patient can be in a sitting or standing posture, etc. The patient position detection device 331 is connected with the support frame 10 through the first fixing hole 121 arranged in the first direction 1211 so as to detect or observe the position of the patient, etc. The thermoplastic film 321 is connected with the beam shaping body 100 through the middle and lower first fixing holes 121 (based on the position shown in Fig. 5, the middle and lower first fixing holes 121 can be the first fixing holes 121 from the third direction to the seventh direction in the clockwise direction) so as to wrap the head or other body parts of the patient and limit the movement thereof, so that the part to be treated is aligned with the beam outlet of the beam collimator 310, and the patient can be treated. Then, except for the first fixing holes 121 and second fixing holes 21 used for fixing the patient position detection device 331 and the thermoplastic film 321, the cover plate assembly 20 is connected with the support frame 10 through the remaining first fixing holes 121 and corresponding second fixing holes 21, so as to further reinforce the connection between the cover plate assembly 20 and the support frame 10.

[0065] Referring to Fig. 5, the patient's head can also be fixed by the head holder 322 when the patient, such as the head or the body, is being treated. The head holder 322 can be connected to the support frame 10 through the first fixing hole 121 in the eighth direction and its corresponding second fixing hole 21. The head holder 322 is then adjusted to a position suitable for the patient being treated by adjusting the cantilever. Finally, the cover plate assembly 20 is connected to the support frame 10 through the remaining first fixing holes 121 and corresponding second fixing holes 21, thereby further reinforcing the connection between the cover plate assembly 20 and the support frame 10.

[0066] Referring to Fig. 6, the patient can also need to be treated in a lying position. At this time, the patient lies on the treatment table, and the auxiliary device 300 (e.g., the monitoring and detection device 330) is connected to the support frame 10 through the first fixing hole 121 above (based on the orientation shown in Fig. 5, the first fixing hole above can be the first fixing hole 121 in the clockwise direction from the seventh direction to the third direction), thereby enabling detection or observation of the patient's treatment site.

[0067] Referring to Fig. 7, before the actual radiation is performed, the parameters of the beam need to be detected by the detection device to determine whether the beam parameters meet the requirements, or when the beam shaping body 100 is inspected, maintained, etc., the intensity, angle, etc. of the neutron beam need to be detected. The support 3321 of the beam detection device 332 can be connected to the support frame 10 through the first fixing hole 121 around the beam hole 15 and the corresponding second fixing hole 21, and the detection module 3322 on the support 3321 can be exposed to the neutron beam to detect its intensity, angle, etc. Then, the cover plate assembly 20 is connected to the support frame 10 through the remaining first fixing holes 121 and corresponding second fixing holes 21, thereby further reinforcing the connection between the cover plate assembly 20 and the support frame 10.

[0068] So far, the technical solutions of the present application have been described in conjunction with the preferred embodiments shown in the drawings, but those skilled in the art will readily understand that the protection scope of the present application is obviously not limited to these specific embodiments. Those skilled in the art can make equivalent changes or replacements to the related technical features without departing from the principles of the present application, and the technical solutions after such changes or replacements will all fall within the protection scope of the present application.

Claims

1. A support frame, characterized by, The support frame includes an outer wall and a partition unit provided inside the outer wall. The partition unit is provided with at least one first fixing hole, and at least one of the first fixing holes can be used to connect with an auxiliary device.

2. The support frame of claim 1, wherein, A beam through-hole is formed at the center of the support frame, and the first fixing holes are arranged at intervals radially around the beam through-hole.

3. The support frame of claim 2, wherein, 4. The support frame of claim 3, wherein, The partition unit includes a plurality of radial walls arranged at intervals in the circumferential direction of the beam through-hole. Each radial wall extends radially along the beam through-hole, and at least one of the first fixing holes is provided on the radial wall.

5. The support frame of claim 2, wherein, 6. The support frame of claim 1, wherein, The radial walls are arranged in a "rice" shape.

7. The support frame of claim 1, wherein, 8. The support frame of claim 7, wherein, The partition unit includes a plurality of circumferential walls surrounding the beam through-hole. Adjacent circumferential walls are spaced apart from each other radially along the beam through-hole, and at least one of the first fixing holes is provided on the circumferential wall.

9. The support frame of claim 8, wherein, 10. A beam shaper, characterized by The partition unit includes a plurality of partition walls, and the first fixing hole is provided at the intersection of two partition walls.

11. The beam shaper of claim 10, wherein, The outer wall is arranged as a square frame member.

12. The beam shaper of claim 10, wherein, The partition unit further includes a strengthening part, and two ends of the strengthening part are respectively connected to two adjacent sides of the square frame member.

14. The beam shaper of claim 12, wherein, The first fixing hole is provided at the connection between the strengthening part and the outer wall.

15. The beam shaper of claim 14, wherein, 16. A neutron capture therapy system characterized by, The beam shaping body includes a support frame and a cover plate assembly provided on one side of the support frame. Among them, 17. The neutron capture therapy system of claim 16, wherein, The support frame includes an outer wall and a partition unit provided inside the outer wall. At least one first fixing hole is provided on the side of the partition unit facing the cover plate assembly, and at least one of the first fixing holes can be used to connect with an auxiliary device.

18. The neutron capture therapy system of claim 16, wherein, A beam through-hole is formed at the center of the support frame, and the first fixing holes are arranged at intervals radially around the beam through-hole. The cover plate assembly includes a second fixing hole, and the first fixing hole and its corresponding second fixing hole can be used to connect with the auxiliary device.

13. The beam shaping body according to claim 12, wherein The auxiliary device and the support frame are connected through the first fixing hole; the support frame and the cover plate assembly are connected through the first fixing hole and the second fixing hole. The cover plate assembly includes a neutron shielding layer baffle, a reflector baffle, and a front baffle that are sequentially away from the support frame. The second fixing hole extends from the front baffle to the neutron shielding layer baffle. An installation groove is formed on the reflector baffle, and the installation groove is used to accommodate the connection structure of the beam collimation device. The neutron capture therapy system includes a beam shaping body and an auxiliary device. The beam shaping body includes a support frame. Among them, The support frame includes an outer wall and a partition unit provided inside the outer wall. At least one first fixing hole is provided on the partition unit, and the auxiliary device can be connected to the support frame through at least one of the first fixing holes. A beam through-hole is formed at the center of the support frame, and the first fixing holes are arranged at intervals radially around the beam through-hole. The auxiliary device includes a beam collimation device, a patient positioning device, and a monitoring and detection device.

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