Phantom, scanning device, manufacturing method, and method for perfusing phantom

Abstract

A resolution phantom, a scanning device, a method for manufacturing the phantom, and a method for perfusing the phantom. The resolution phantom comprises: a housing (100), two axial ends of which are respectively configured with a liquid inlet (121) and an air extraction port (131); and an inner core (200), configured with fine holes (210), the fine holes (210) penetrating through the inner core (200) along an axial direction of the inner core (200), wherein the liquid inlet (121), the fine holes (210), and the air extraction port (131) are in communication. The defect that bubbles are easily generated in the prior art is overcome, thereby improving the accuracy of resolution evaluation.

Description

phantom, scanning equipment, manufacturing method and method of casting thereon

[0001] Related applications

[0002] This application claims priority to Chinese Patent Application No. 202422139306.7, filed on August 30, 2024, entitled "Resolution Phantom and Scanning Device", and Chinese Patent Application No. 202411218005.1, filed on August 30, 2024, entitled "Resolution Phantom, Scanning Device, Manufacturing Method and Method of Instilling Thereon", the entire contents of which are incorporated herein by reference. Technical Field

[0003] This invention relates to the field of scientific instrument technology, and in particular to a phantom, scanning device, manufacturing method, and method of instilling it. Background Technology

[0004] In nuclear medicine clinical imaging, physical phantoms are physical structures made of low-scattering, low-absorption materials, constructed into multiple chambers to be infused with radiopharmaceuticals, simulating human organs, tissues, and lesions. Quality control is crucial for ensuring the quality and safety of nuclear medicine imaging, and phantoms are essential tools for this purpose. Furthermore, phantoms are used for equipment acceptance, performance evaluation, comparisons between different devices, imaging methods, and reconstruction algorithms, and comparisons between different devices before multi-center clinical trials. Their design varies depending on the modality, clinical needs, or research requirements. In medical imaging, spatial resolution has always been one of the most important performance indicators. Higher spatial resolution means smaller lesions can be detected. Early-stage cancer lesions are often small; therefore, single-photon emission computed tomography (SPECT) and positron emission tomography (PET), with their high spatial resolution, can improve the detection rate of early-stage cancer.

[0005] Phantoms with internal microstructures are widely used in such applications for calibrating and verifying system performance parameters. The Derenzo phantom, for example, is the most widely used resolution phantom in nuclear medicine for determining image quality. A Derenzo phantom typically consists of a shell and an inner core, with the core housed within the shell. During use, the hot-pot orifice contains a radioactive solution and is placed inside the sealed phantom. Image acquisition is then performed, and the image resolution is determined based on the images. The inner core has six different diameter hot-pot orifices. For micro-PET systems, the diameter of these orifices in the phantom core is very small, for example, 0.8, 1.0, 1.2, 1.5, 1.8, and 2.0 mm. The structure of the injection channels and the small diameter of the hot-pot orifices in existing phantoms make it highly susceptible to air bubbles during the filling process due to capillary action, thus affecting the test results. Summary of the Invention

[0006] One aspect of this application provides a phantom, the phantom comprising:

[0007] The outer casing has a liquid inlet and an air outlet at each end;

[0008] The inner core has a porous structure;

[0009] The liquid inlet, the perforated structure, and the air extraction port are connected to each other.

[0010] In some embodiments,

[0011] The outer casing has a liquid inlet and an air extraction port at both ends along the axial direction;

[0012] The porous structure is provided with fine holes, which penetrate the inner core along the axial direction of the inner core;

[0013] The liquid inlet, the fine hole, and the air extraction port are connected to each other.

[0014] In some embodiments, the housing includes:

[0015] A shell, enclosing the inner core;

[0016] A liquid suction connector is provided at one end of the housing, and the liquid suction connector is provided with a liquid inlet that passes through the liquid suction connector;

[0017] An air extraction connector is located at the other end of the housing, and the air extraction connector is provided with an air extraction port that passes through the air extraction connector.

[0018] In some embodiments, the housing includes:

[0019] The main section is constructed as a columnar structure;

[0020] A first transition section is provided at one end of the main body section, and the end of the first transition section opposite to the main body section is connected to the liquid suction connector.

[0021] The second transition section is located at the other end of the main body section, and the end of the second transition section opposite to the main body section is connected to the air extraction connector.

[0022] The first transition section and the second transition section are constructed as cones.

[0023] In some embodiments, the inner end faces of the housing at both ends along the axial direction have a first interlayer space and a second interlayer space between them and the two ends of the inner core. The first interlayer space is connected to the liquid inlet, and the second interlayer space is connected to the air extraction port. The two ends of the fine hole are respectively connected to the first interlayer space and the second interlayer space.

[0024] In some embodiments, the phantom further includes:

[0025] The bracket is disposed in the second interlayer space, and its two ends are respectively supported by the inner core and the end of the air extraction connector. The bracket is constructed as a hollow structure.

[0026] In some embodiments, the support includes:

[0027] Multiple support ribs are arranged at intervals in a divergent manner.

[0028] In some embodiments, the core portion of the inner core is provided with a connecting hole that extends through the inner core along the axial direction of the inner core, and the connecting hole is connected to the first interlayer space and the second interlayer space.

[0029] In some embodiments, the diameter of the connecting hole at the end near the liquid suction connector is larger than the diameter at the end near the air suction connector; the connecting hole is configured as a stepped hole.

[0030] In some embodiments, the outer shell and the inner core are integrally formed by 3D printing, and the outer shell and the inner core are a single unit.

[0031] In some embodiments, at least one end of the inner core is tapered.

[0032] In some embodiments, a limiting groove is provided on the outer peripheral surface of the housing to prevent the housing from rolling.

[0033] In some embodiments, the micropore structure is a plurality of hot stove hole groups, each hot stove hole group including a plurality of spaced micropores.

[0034] In some embodiments, the liquid inlet, the fine hole, and the air extraction port form a liquid injection channel.

[0035] In some embodiments, the liquid inlet is used to connect to the needle of the syringe, and the air extraction port is used to connect to the syringe barrel.

[0036] In some embodiments, the phantom is used for nuclear medicine simulation imaging.

[0037] In some embodiments, the phantom is a resolution phantom or an IQ phantom.

[0038] Another aspect of this application provides a scanning device, which is a nuclear medicine imaging device, including the phantom as described in any of the above embodiments.

[0039] Another aspect of this application provides a method for manufacturing a mold as described in any of the above embodiments, the method comprising the following steps:

[0040] Obtain the three-dimensional model of the phantom;

[0041] The mold body is 3D printed in one piece according to the three-dimensional model.

[0042] In some embodiments, the step of 3D printing the mold body in one piece according to the three-dimensional model includes the following steps:

[0043] The photocurable resin is scanned with light according to the three-dimensional model. The photocurable resin is cured after being irradiated with light to form a mold corresponding to the three-dimensional model.

[0044] Another aspect of this application provides a method for infusion of a phantom according to any of the above embodiments, the method comprising the following steps:

[0045] Immerse one end of the liquid inlet below the liquid surface, and use an air extraction tool to extract air from one end of the air extraction port until the solution fills the mold body.

[0046] In some embodiments, the suction tool includes a piston, and the method further includes a venting step, the venting step comprising:

[0047] Seal the liquid inlet;

[0048] Pull the piston away from the air extraction port to create a negative pressure inside the mold.

[0049] Open the inlet, restore the piston to its original position, and push the solution from the vacuum tool into the mold body.

[0050] In some embodiments, the method includes:

[0051] Repeat the venting steps until there are no more air bubbles in the fine hole, then remove the venting tool and seal the venting port and liquid inlet.

[0052] In some embodiments, immersing one end of the liquid inlet below the liquid surface includes:

[0053] Connect the suction tool to the inlet and immerse the suction tool below the liquid surface;

[0054] The air extraction tool is the syringe barrel of a syringe, and the liquid aspiration tool is the needle of a syringe.

[0055] Details of various embodiments of the present invention will be described in the following drawings and description. Other features, problems solved, and technical effects of the present invention will be readily understood by those skilled in the art based on the specification, drawings, and claims. Attached Figure Description

[0056] To more clearly illustrate the technical solutions in the embodiments of this application or the conventional technology, the drawings used in the description of the embodiments or the conventional technology will be briefly introduced below. Obviously, the drawings described below are only embodiments of this application. For those skilled in the art, other drawings can be obtained based on the disclosed drawings without creative effort.

[0057] Figure 1 is a schematic diagram of the external outline of a resolution phantom provided in an embodiment of this application;

[0058] Figure 2 is a cross-sectional view of a resolution phantom provided in an embodiment of this application;

[0059] Figure 3 is a schematic diagram of the cross-section along the AA direction in Figure 2;

[0060] Figure 4 is a cross-sectional view of the inner core provided in an embodiment of this application;

[0061] Figure 5 is a cross-sectional view of a resolution phantom provided in another embodiment of this application;

[0062] Figure 6 is a cross-sectional view of a resolution phantom provided in another embodiment of this application;

[0063] Figure 7 is a flowchart illustrating a method for manufacturing a resolution phantom according to an embodiment of this application;

[0064] Figure 8 is a flowchart illustrating the infusion method for a resolution phantom provided in an embodiment of this application.

[0065] Reference numerals: Outer shell 100; Housing 110; Main body section 111; Limiting groove 1111; Transition section 112; First transition section 112a; Second transition section 112b; Liquid suction connector 120; Liquid inlet 121; Air suction connector 130; Air suction port 131; Inner core 200; Fine hole 210; Connecting hole 220; First stepped hole 220a; Second stepped hole 220b; First interlayer space 300; Second interlayer space 400; Reinforcing rib 410; Bracket 500; Support column 510; Support rib 520; Support shell 530. Detailed Implementation

[0066] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0067] Referring to Figures 1 to 6, in some embodiments, a phantom is provided, comprising an outer shell 100 and an inner core 200. The outer shell 100 has a liquid inlet 121 and an air extraction port 131 at its two ends. The inner core 200 has a porous structure. The liquid inlet 121, the porous structure, and the air extraction port 131 are interconnected. In some embodiments of this application, the phantom is used for nuclear medicine simulation imaging. In some embodiments, the liquid inlet 121 is used to connect to the needle of a syringe, and the air extraction port 131 is used to connect to the syringe barrel. In some embodiments, the phantom is a resolution phantom or an IQ phantom.

[0068] In embodiments of this application, the porous structure can be filled with a liquid, specifically a radioactive solution, such as a tracer for nuclear medicine imaging. In embodiments of this application, the structure of the inner core 200 can be configured according to the type of phantom used in nuclear medicine simulation imaging to suit different testing requirements. In some embodiments, the phantom can be used for quality control testing of nuclear medicine imaging. In embodiments of this application, the phantom can be a resolution phantom, an IQ phantom, etc., used to evaluate the resolution, image quality, quantitative performance, etc., of nuclear medicine imaging equipment.

[0069] In some embodiments of this application, the phantom is a resolution phantom. The resolution phantom provided in some embodiments of this application includes an outer shell 100 and an inner core 200. The outer shell 100 has a liquid inlet 121 and an air extraction port 131 at both ends along the axial direction. The perforated structure has fine holes 210 that penetrate the inner core 200 along its axial direction. The liquid inlet 121, fine holes 210, and air extraction port 131 are interconnected.

[0070] In some embodiments, the fine holes 210 are configured as multiple sets of heating stove holes, each set of heating stove holes including multiple spaced-apart fine holes 210. In the embodiments of this application, the fine holes 210 are configured as multiple sets of heating stove holes, and the fine holes can be heating stove holes.

[0071] In some embodiments, the inlet 121, the fine hole 210, and the air extraction port 131 form an injection channel.

[0072] This application provides a resolution phantom, with an outer shell 100 supporting and sealing an inner core 200. An inlet 121 and an outlet 131 are provided at both ends of the outer shell 100. During the injection of a radioactive solution, air is drawn out through the outlet 131, creating a negative pressure within the fine holes 210 of the inner core 200. This draws the radioactive liquid from the inlet 121 into the fine holes 210, thus enabling resolution evaluation. The fine holes 210 are configured to extend through the pores of the inner core 200 along its axial direction to facilitate the filling of the radioactive solution. In this embodiment, the inlet 121, the fine holes 210, and the outlet 131 are connected to form an injection channel, and the liquid flows from the inlet 121 to the outlet 131, ensuring a unidirectional flow. This allows air bubbles in the liquid within the fine holes 210 to be removed during injection, overcoming the tendency for air bubbles to form in existing technologies and improving the accuracy of resolution evaluation.

[0073] Understandably, in this embodiment, the inner core 200 is constructed with six groups of heating holes of different sizes, and the apertures 210 in each group of heating holes are the same. Setting different groups of heating holes with apertures 210 of different diameters facilitates evaluation at different resolutions. Specifically, the apertures 210 in each group of heating holes are arranged in an equilateral triangle orientation, dividing the entire inner core 200 into six equal regions.

[0074] In some embodiments, the resolution phantom is infused using an injection assembly. The injection assembly includes a vacuum tool connected to a vacuum port. The vacuum tool's suction and venting functions enable the injection of liquid into the resolution phantom and the removal of air bubbles from within the phantom.

[0075] In some embodiments, the infusion assembly further includes a suction tool connected to the inlet and capable of being submerged below the surface of the radioactive liquid.

[0076] In some embodiments, the air extraction tool is the syringe barrel of a syringe. In some embodiments, the liquid aspiration tool is the needle of a syringe.

[0077] In this embodiment, the liquid inlet 121 is used to connect the needle of the syringe, and the air extraction port 131 is used to connect the syringe barrel. When injecting liquid into the resolution phantom, a liquid suction tool, such as a needle, is connected to the liquid inlet; an air extraction tool, such as a syringe barrel, is connected to the air extraction port. Then, the needle is immersed below the surface of the radioactive liquid, and the liquid injection into the resolution phantom and the removal of air bubbles from the phantom are completed by pulling the piston of the syringe.

[0078] In one embodiment, the outer shell 100 includes a shell 110, a liquid suction connector 120, and an air suction connector 130. The shell 110 is wrapped around the inner core 200. The liquid suction connector 120 is located at one end of the shell 110 and has a liquid inlet 121 that passes through the liquid suction connector 120. The air suction connector 130 is located at the other end of the shell 110 and has an air suction port 131 that passes through the air suction connector 130.

[0079] The housing 110 encloses the inner core 200 to protect and seal it. The suction connector 120 connects to a suction tool, such as a needle, while the air extraction connector 130 connects to an extraction tool, such as the syringe barrel. A liquid inlet 121 is provided on the suction connector 120 to allow liquid entering from the needle's inner bore to flow into the fine holes 210 of the inner core 200. Similarly, an air extraction port 131 is provided on the air extraction connector 130 to allow air to be extracted from the inner core 200 via the syringe barrel, creating a negative pressure within the inner core 200. Preferably, both the suction connector 120 and the air extraction connector 130 are Luer connectors. Specifically, the outer circumferential surface of the suction connector 120 is a tapered connector with a slight inclination angle. The Luer connector of the needle can be directly fitted onto the suction connector 120 to achieve the connection between the needle and the suction connector 120. The outer circumferential surface of the suction connector 130 is provided with external threads, and correspondingly, the head of the syringe is provided with internal threads to mate with the external threads on the suction connector 130 to achieve the connection between the syringe and the suction connector 130.

[0080] In this embodiment, the liquid aspiration connector 120 is configured as a Luer connector corresponding to the Luer connector of the needle, and the air suction connector 130 is configured as a Luer connector corresponding to the Luer connector of the syringe. This facilitates connection with the needle and syringe and ensures airtightness at the connection.

[0081] In one embodiment, the inner end faces of the housing 110 at both ends along the axial direction are spaced apart from the two ends of the inner core 200 to form a first interlayer space 300 and a second interlayer space 400. The first interlayer space 300 is connected to the liquid inlet 121, the second interlayer space 400 is connected to the air extraction port 131, and the two ends of the fine hole 210 are connected to the first interlayer space 300 and the second interlayer space 400, respectively.

[0082] By setting the inner end faces of the housing 110 at both ends along the axial direction to be spaced apart from the two ends of the inner core 200, two interlayer spaces are formed between the housing 110 and the inner core 200. This allows the two ends of all the fine holes 210 on the inner core 200 to be connected to the first interlayer space 300 and the second interlayer space 400, respectively. This facilitates the connection of the liquid inlet 121 and the air extraction port 131 to all the fine holes 210, so that during liquid injection, liquid can be introduced through the liquid inlet 121 and air can be extracted through the air extraction port 131 to achieve liquid injection into all the fine holes 210.

[0083] In one embodiment, the housing 110 includes a main body segment 111 and a transition segment 112. The main body segment 111 is constructed as a columnar structure. The transition segments 112 are respectively provided at both ends of the main body segment 111. The end of the transition segment away from the main body segment 111 is connected to a liquid suction connector 120 or a vacuum connector 130. The transition segment 112 is constructed as a cone shape, and the cross-sectional dimension of the transition segment 112 gradually decreases from the main body segment 111 in the direction away from the main body segment 111.

[0084] Specifically, the main body segment 111 of the shell 110 is a cylindrical structure that wraps around the outer periphery of the inner core 200. Transition segments 112 are provided at both ends of the main body segment 111, with one end of each transition segment 112 facing away from the main body segment 111 connecting to the liquid suction connector 120 and the air suction connector 130, respectively. The transition segments 112 are primarily used to connect the main body segment 111 to the liquid suction connector 120 and the air suction connector 130. Specifically, the transition segments 112 are constructed as conical structures to facilitate the transition of the shell 110 to the liquid suction connector 120 and the air suction connector 130 from coarse to fine, and from fine to coarse.

[0085] In some embodiments, transition segment 112 includes a first transition segment 112a and a second transition segment 112b.

[0086] The first transition section 112a is located at one end of the main body section 111, and the end of the first transition section away from the main body section 111 is connected to the liquid suction connector 120.

[0087] The second transition section 112b is located at the other end of the main body section 111, and the end of the second transition section away from the main body section 111 is connected to the air extraction connector 130.

[0088] The first transition section 112a and the second transition section 112b are constructed as cones.

[0089] Referring to FIG5 for understanding, in some embodiments, at least one end of the inner core 200 is tapered.

[0090] In some embodiments, the end face of the inner core 200 facing the liquid suction connector 120, i.e., the first interlayer space 300, is tapered, with the tip of the tapered shape facing the liquid inlet 121. Thus, the first interlayer space 300 formed by the inner end face of the transition zone and the inner end face of the inner core 200 is a tapered interlayer space.

[0091] In some embodiments, the end face of the inner core 200 on one side of the second interlayer space 400 is a concave cone shape that is recessed away from the air extraction port, and the cone opening is directed toward the air extraction port 131.

[0092] By setting at least one end of the inner core 200 to be tapered, while ensuring that the liquid inlet 121 and the air extraction port 131 are connected to the fine hole 210, the interlayer space can be made relatively smaller and the inner core volume smaller, and the structure can be more stable and easier to manufacture. This helps to save solution and reduce manufacturing costs during liquid injection, thereby reducing the cost of use.

[0093] In one embodiment, the outer shell 100 and the inner core 200 are integrally formed by 3D printing. In this embodiment, the outer shell 100 and the inner core 200 are integrally formed by 3D printing, resulting in a single unit. This reduces the number of parts, thereby lowering production costs; it also enables the integral forming of the high-resolution mold, reducing processing steps and further reducing production costs and improving efficiency. The materials of the outer shell 100 and the inner core 200 are not limited and can be materials such as polyethylene or polypropylene.

[0094] To improve the venting efficiency of air bubbles within the fine orifice 210 during liquid injection, in this embodiment, the end face of the inner core 200 facing the suction connector 130 is configured as a concave conical surface extending towards the suction connector 120. This allows air bubbles to be drawn into the concave conical space during syringe aspiration, facilitating their removal from the outer shell 100. Since the resolution phantom is entirely 3D printed, to enhance the structural strength of the shell 110, the end face of the transition section 112 facing the inner core 200 is made flat, and a through hole is provided in the transition section 112 to connect with the suction port on the suction connector 130. This ensures efficient venting while reducing the volume of the second interlayer space 400, thereby saving on the amount of radioactive solution used.

[0095] In one embodiment, the resolution module further includes a support 500 disposed within the second interlayer space 400. The two ends of the support 500 are respectively supported by the inner core 200 and the end of the air extraction connector 130. The support 500 is constructed as a hollow structure so that the air extraction port 131, the second interlayer space 400 and the fine hole 210 are connected.

[0096] Because the second interlayer space 400 is relatively large, a support 500 is installed within it, with both ends of the support 500 supporting the inner core 200 and the suction connector 130, respectively. This prevents the risk of the transition section 112 collapsing during 3D printing, thus ensuring the molding effect. Furthermore, by installing the support 500 between the inner core 200 and the suction connector 130, the liquid can be turbulently induced, improving the venting effect and enhancing the overall strength of the resolution mold. The support 500 is constructed with a hollow structure, allowing the suction port 131, the second interlayer space 400, and the fine hole 210 to communicate, facilitating gas flow through a syringe. To improve the structural strength of the resolution mold, multiple spaced reinforcing ribs 410 can be provided within the second interlayer space 400. In some embodiments, the support 500 includes multiple supporting ribs 520, which are arranged in a radiating pattern. In some embodiments, the supporting ribs 520 are reinforcing ribs. In some embodiments, a plurality of support ribs 520 converge and connect together at the central axis of the resolution module.

[0097] In one embodiment, the support 500 includes a support column 510, support ribs 520, and a support shell 530. Multiple support ribs 520 are arranged in a divergent pattern at intervals. The ends of the multiple support ribs 520 that are close to each other are connected to the support column 510, while the ends of the multiple support ribs 520 that are far apart from each other are supported on the end face of the air extraction connector 130 facing into the second interlayer space 400. The air extraction port 131 is connected to the second interlayer space 400 through the gaps between the support ribs 520. The support shell 530 has a cavity with an opening at one end and a through hole communicating with the cavity. The end face of the support shell 530 with the opening is supported on the inner core 200, and the end of the support shell 530 facing away from the inner core 200 is fixedly connected to the support column 510.

[0098] Specifically, the support column 510 is a cylindrical structure, and there are multiple support ribs 520. In this embodiment, six support ribs 520 are arranged radially in the radial direction of the shell and also radially in the axial direction of the shell. During 3D printing, the air extraction connector is printed first, followed by the sequential printing of the support ribs, support column, support shell, and inner core along the axial direction of the mold. The six support ribs 520 are inclined away from the axis of the support column 510 and connected to the end of the air extraction connector. The support shell 530 is a curved shell 110, with its large end face supporting the conical concave surface of the inner core 200. This increases the contact area between the support shell and the inner core 200, thereby improving the support effect. Through holes are provided in the support shell 530 to allow for interconnection between the spaces on both sides of the support shell 530.

[0099] In one embodiment, the core of the inner core 200 is provided with a connecting hole 220 that extends through the inner core 200 along its axial direction, and the connecting hole 220 is connected to the first interlayer space 300 and the second interlayer space 400.

[0100] Since the entire resolution mold body is integrally formed using 3D printing technology, a connecting hole 220 is provided in the core of the inner core 200 to facilitate the outflow of excess resin during the 3D printing process, preventing excess resin from accumulating in the cavity and affecting the molding effect. In this embodiment, the connecting hole 220 is axially arranged through the inner core 200. Since the connecting hole 220 is located in the core of the inner core 200, it is beneficial for gas to flow through the core during liquid injection, thereby facilitating venting. Furthermore, the connecting hole 220 is configured as a stepped hole, with the diameter of the end near the liquid suction connector 120 being larger than the diameter of the end near the air suction connector 130. This diameter change allows air bubbles to be crushed, thus facilitating their expulsion. In some embodiments, the connecting hole 220 includes a first stepped hole 220a and a second stepped hole 220b. The first stepped hole 220a is near the liquid suction connector 120, and the second stepped hole 220b is near the air suction connector 130. The diameter of the first stepped hole 220a is larger than the diameter of the second stepped hole 220b.

[0101] In one embodiment, a limiting groove 1111 is provided on the outer peripheral surface of the housing 100, and the limiting groove 1111 extends along the axial direction of the housing 100. By providing the limiting groove 1111 extending along the axial direction of the housing 100 on the outer peripheral surface of the housing 100, the integrity of the outer peripheral surface of the housing 100 is disrupted. Therefore, when the housing 100 is placed flat on a plane, the limiting groove 1111 can prevent the housing 100 from rolling, thereby achieving the limiting of the entire resolution module. Specifically, the limiting groove 1111 is provided on the main body segment 111.

[0102] One embodiment of this application also provides a scanning device, which is a nuclear medicine imaging device, including the resolution phantom as described above. By applying the resolution phantom as described above in the scanning device, the liquid inlet 121, the fine hole 210, and the air extraction port are connected to form a liquid injection channel, and the liquid flows from the liquid inlet 121 to the air extraction port 131, making the liquid flow direction unidirectional. This allows air bubbles in the liquid within the fine hole 210 to be expelled during the liquid injection process, overcoming the defect of easy bubble generation in the prior art, thereby improving the accuracy of resolution assessment. Specifically, the scanning device can be a PET (Positron Emission Tomography) scanner or a SPECT (Single Photon Emission Tomography) scanner, etc.

[0103] As shown in Figure 7, one embodiment of this application provides a method for manufacturing a resolution phantom, which includes the following steps:

[0104] S100, Obtain the 3D model of the resolution model;

[0105] S200: Based on the three-dimensional model, the resolution mold is 3D printed in one piece.

[0106] Furthermore, the resolution phantom is 3D printed in one piece according to the three-dimensional model, including the following steps:

[0107] The light-curing resin is scanned using a 3D model. The resin is cured after being irradiated by light to form a resolution model corresponding to the 3D model.

[0108] The light scanning sequence proceeds from the air extraction port to the liquid inlet port.

[0109] Specifically, the 3D model of the resolution phantom is set according to the structure described above. After obtaining the modeled 3D model, the printing equipment is controlled to scan the liquid photocurable resin. It can be understood that the light only scans the corresponding positions of the 3D model, essentially slicing the 3D model to form a 2D pattern. The light scans layer by layer along this 2D pattern to form the required resolution phantom corresponding to the 3D model. In this embodiment, the suction connector end is scanned first, then along the axial direction, and finally the liquid suction connector end is scanned. Due to the use of photocurable 3D printing technology, compared to traditional 3D printing processes, it has the advantages of faster curing speed and higher production efficiency.

[0110] In some embodiments, a method for filling the resolution phantom as described above is also provided, the method comprising the steps of: immersing one end of the inlet below the liquid surface, and using an air extraction tool to extract air from one end of the air extraction port until the solution fills the resolution phantom.

[0111] In some embodiments, the vacuuming tool includes a piston, and the method further includes a venting step, the venting step including: sealing the liquid inlet; pulling the piston away from the vacuuming port to create a negative pressure inside the resolution mold; opening the liquid inlet, restoring the position of the piston, and pushing the solution inside the vacuuming tool into the resolution mold.

[0112] In some embodiments, the method includes: repeating the venting step until there are no air bubbles in the fine hole, removing the venting tool, and sealing the venting port and the liquid inlet.

[0113] In some embodiments, immersing one end of the inlet below the liquid surface includes: connecting a suction tool to the inlet and immersing the suction tool below the liquid surface; the suction tool is the syringe barrel of a syringe, and the suction tool is the needle of a syringe.

[0114] Referring to Figure 8, one embodiment of this application also provides a method for instillation based on the above-described resolution phantom, the method comprising the following steps:

[0115] S10. Connect the air extraction tool to the air extraction port and the liquid suction tool to the liquid inlet.

[0116] S20. After pressing the piston of the vacuum tool to its limit position towards the vacuum port, immerse the liquid suction tool below the liquid surface, pull the piston until the solution fills the resolution mold and enters the vacuum tool.

[0117] S30. Remove the liquid suction tool and seal the liquid inlet;

[0118] S40. Pull the piston away from the air intake port;

[0119] S50. Restore the position of the piston and push the solution in the vacuum tool into the resolution mold body;

[0120] S60. After there are no more air bubbles in the hot stove hole, remove the air extraction tool and seal the air extraction port.

[0121] In some embodiments, the liquid aspiration tool can be a needle in a syringe, and the air extraction tool can be a syringe barrel. First, connect the air extraction connector 130 of the prepared mold to the syringe barrel, and connect the needle to the liquid aspiration connector 120 of the mold. Then, press the syringe piston to its deepest point, immersing the needle downwards into the radioactive solution to be extracted. Pull the piston back until the solution fills the mold and a suitable amount enters the syringe barrel. Remove the needle and plug the liquid aspiration connector 120 to prevent leakage. Keeping the syringe barrel downwards, pull the syringe piston outwards to create a high negative pressure inside the syringe barrel. At this time, small air bubbles in the heating element will expand, rise, and enter the syringe barrel. Return the piston to its original position and push the solution in the syringe barrel into the mold to fill the volume previously occupied by the air bubbles. Repeat the above air extraction steps until the air bubbles are completely removed. Finally, remove the mold from the syringe barrel and seal the air extraction connector 130 with a plug.

[0122] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0123] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A phantom, characterized in that, The phantom includes: The outer casing (100) has a liquid inlet (121) and an air extraction port (131) at each end; The inner core (200) has a porous structure; The liquid inlet (121), the perforated structure, and the air extraction port (131) are connected.

2. The phantom according to claim 1, characterized in that, The outer casing (100) is provided with a liquid inlet (121) and an air extraction port (131) at both ends along the axial direction; The porous structure is provided with fine holes (210), which penetrate the inner core (200) along the axial direction of the inner core (200); The liquid inlet (121), the fine hole (210), and the air extraction port (131) are connected.

3. The phantom according to claim 2, characterized in that, The housing (100) includes: The shell (110) is wrapped around the inner core (200); A liquid suction connector (120) is provided at one end of the housing (110), and a liquid inlet (121) is provided on the liquid suction connector (120) through the liquid suction connector (120); An air extraction connector (130) is provided at the other end of the housing (110), and an air extraction port (131) is provided on the air extraction connector (130) through the air extraction connector (130).

4. The phantom according to claim 3, characterized in that, The housing (110) includes: The main segment (111) is constructed as a columnar structure; A first transition section (112a) is provided at one end of the main body section (111), and the end of the first transition section opposite to the main body section (111) is connected to the liquid suction connector (120); A second transition section (112b) is provided at the other end of the main body section (111), and the end of the second transition section opposite to the main body section (111) is connected to the air extraction connector (130); The first transition segment (112a) and the second transition segment (112b) are constructed as cones.

5. The phantom according to claim 3, characterized in that, The housing (110) has a first interlayer space (300) and a second interlayer space (400) between the inner end faces of both ends along the axial direction and the two ends of the inner core (200). The first interlayer space (300) is connected to the liquid inlet (121), and the second interlayer space (400) is connected to the air extraction port (131). The two ends of the fine hole (210) are respectively connected to the first interlayer space (300) and the second interlayer space (400).

6. The phantom according to claim 5, characterized in that, The phantom also includes: A bracket (500) is disposed in the second interlayer space (400). The two ends of the bracket (500) are respectively supported by the inner core (200) and the end of the air extraction connector (130). The bracket (500) is constructed as a hollow structure.

7. The phantom according to claim 6, characterized in that, The support (500) includes: Multiple support ribs (520) are arranged in a divergent manner.

8. The phantom according to claim 5, characterized in that, The core (200) has a connecting hole (220) that extends through the core (200) along its axial direction. The connecting hole (220) is connected to the first interlayer space (300) and the second interlayer space (400).

9. The phantom according to claim 8, characterized in that, The diameter of the end of the connecting hole (220) near the liquid suction connector (120) is larger than the diameter of the end near the air suction connector (130); the connecting hole (220) is configured as a stepped hole.

10. The phantom according to claim 1, characterized in that, The outer shell (100) and the inner core (200) are integrally formed by 3D printing, and the outer shell (100) and the inner core (200) are a whole.

11. The phantom according to any one of claims 1-10, characterized in that, At least one end of the inner core (200) is tapered.

12. The phantom according to any one of claims 1-10, characterized in that, A limiting groove (1111) is provided on the outer peripheral surface of the outer shell (100), and the limiting groove (1111) is used to prevent the outer shell from rolling.

13. The phantom body according to any one of claims 2-10, characterized in that, The micro-hole structure comprises multiple sets of hot stove hole groups, each of which includes multiple spaced micro-holes (210).

14. The phantom according to any one of claims 1-10, characterized in that, The liquid inlet (121), the perforated structure, and the air extraction port (131) form a liquid injection channel.

15. The phantom according to claim 14, characterized in that, The liquid inlet (121) is used to connect the needle of the syringe, and the air extraction port (131) is used to connect the syringe barrel.

16. The phantom according to claim 1, characterized in that, The phantom is used for nuclear medicine simulation imaging.

17. The phantom according to claim 1, characterized in that, The phantom is a resolution phantom or an IQ phantom.

18. A scanning device, characterized in that, The scanning device is a nuclear medicine imaging device, including the phantom as described in any one of claims 1-17.

19. A method for manufacturing a mold according to any one of claims 1-17, characterized in that, The method for manufacturing the mold includes the following steps: Obtain the three-dimensional model of the phantom; The mold body is 3D printed in one piece according to the three-dimensional model.

20. The method for manufacturing the mold according to claim 19, characterized in that, The step of 3D printing the mold body in one piece according to the three-dimensional model includes the following steps: The photocurable resin is scanned with light according to the three-dimensional model. The photocurable resin is cured after being irradiated with light to form a mold corresponding to the three-dimensional model.

21. A method for casting a mold according to any one of claims 1-17, characterized in that, The method includes the following steps: Immerse one end of the liquid inlet below the liquid surface, and use an air extraction tool to extract air from one end of the air extraction port until the solution fills the mold body.

22. The method according to claim 21, characterized in that, The air extraction tool includes a piston, and the method further includes an exhaust step, which includes: Seal the liquid inlet; Pull the piston away from the air extraction port to create a negative pressure inside the mold. Open the inlet, restore the piston to its original position, and push the solution from the vacuum tool into the mold body.

23. A method for casting a phantom according to claim 22, characterized in that, The method includes: Repeat the venting steps until there are no more air bubbles in the fine hole, then remove the venting tool and seal the venting port and liquid inlet.

24. The method according to claim 21, characterized in that, The step of immersing one end of the liquid inlet below the liquid surface includes: Connect the suction tool to the inlet and immerse the suction tool below the liquid surface; The air extraction tool is the syringe barrel, and the liquid aspiration tool is the syringe needle.

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