Apparatus and method for automatically calibrating ocular fundus imaging with three-band light

Abstract

Disclosed are an apparatus and method for automatically calibrating ocular fundus imaging with three-band light. The apparatus comprises a central optical path channel, wherein the central optical path channel comprises a fundus lens, a short-wave-pass dichroic mirror, a first intermediate optical path correction module, a long-wave-pass dichroic mirror, a second intermediate optical path correction module, and an intermediate infrared camera, which are sequentially arranged; the apparatus further comprises two side infrared cameras at a certain angle to the central optical path channel, an annular light strip located around the fundus lens, a guidance display located below the long-wave-pass dichroic mirror, an OCT sample arm electrically controlled lifting module, and an OCT optical path channel located directly below the short-wave-pass dichroic mirror. The apparatus can acquire information of a human face, a human eye, and an eyeball gaze direction, and transmit an OCT light beam to a pupil, thereby eliminating the restriction that a human head must be strictly fixed during OCT ocular fundus imaging; visual guidance suppresses the adverse effect of shaking of the eyeball gaze direction on imaging, and automatically adjusts an OCT optical path spacing to adapt to groups with different vision, thereby improving the efficiency and quality of ocular fundus imaging.

Description

Device and method for three-band light automatic calibration fundus imaging TECHNICAL FIELD

[0001] The present application relates to the field of optical imaging technology, in particular to a device and method for OCT fundus imaging related to vision self-correction, human eye induction and human eye automatic calibration. BACKGROUND

[0002] Optical coherence tomography (OCT) can perform high-resolution, non-invasive tomography on biological tissues and materials. Ophthalmic coherence tomography has become the gold standard for managing various eye diseases. Desktop OCT systems are commonly used for ophthalmic diagnosis due to their non-contact and high-resolution three-dimensional imaging advantages. However, the bulkiness of the desktop design and the requirement for professional operators to precisely align the device with the human eye limit the application of desktop OCT systems in ophthalmic specialist clinics and ophthalmic imaging rooms. In addition, desktop OCT also has strict eye examination requirements for patients, such as sitting posture, fixing the forehead and chin, and maintaining gaze, which significantly hinders the routine assessment and diagnosis of eye diseases for patients who cannot cooperate due to intelligence or physical reasons. Robotic automation of ophthalmic OCT provides a promising solution for obtaining high-quality images and reducing patient cooperation and operational skill requirements. OCT imaging robots enable patients to be free from the constraints of mechanical fixation devices during imaging through active alignment and precise motion tracking of the eye. In addition, OCT imaging robots can avoid motion artifacts caused by operator fatigue or physiological tremor by replacing human operators, ensuring accurate alignment during imaging. OCT imaging robots have the potential to revolutionize the way people care for their eyes. However, OCT imaging robots must require a shorter working distance to achieve a wider range of fundus imaging, and accurate alignment of the human eye during OCT imaging at a short working distance is a challenging problem for OCT imaging robots. In addition, people with poor vision have varying degrees of myopia or hypermetropia, and it is necessary to automatically match OCT fundus scanning for people with different vision. SUMMARY

[0003] The present application aims to solve the problem of cooperation between short-distance OCT imaging and accurate alignment of the human eye. The present application provides a device for three-band light automatic calibration fundus imaging, which is as follows:

[0004] The device for three-waveband light automatic calibration fundus imaging comprises a central light path channel, the central light path channel comprises, in sequence, a fundus mirror, a short-wave-pass dichroic mirror, an intermediate light path correction module one, a long-wave-pass dichroic mirror, an intermediate light path correction module two and an intermediate infrared camera, wherein two side infrared cameras are symmetrically arranged on both sides of the short-wave-pass dichroic mirror, and the two side infrared cameras are placed at a certain angle with the central light path channel and face the front of the fundus mirror; an annular lamp strip is arranged at the front end of the fundus mirror; the plane of the short-wave-pass dichroic mirror and the long-wave-pass dichroic mirror is at an angle of 45° with the light path of other components in the central light path channel. The side infrared cameras are used to capture the images of the face and the eyes, and provide part of the relative position information for aligning the imaging device to the pupil of the eyes at the ideal working distance; the placement positions of the two side cameras need to meet that the field of view obtained by the two side cameras at the working distance can cover the face. The central light path channel is used to transmit the complete image of the eyes and the pupil when aligning the eyes, and is also used to transmit the eye-induced light and the OCT imaging light beam. The specific functions of the components in the central light path channel are as follows: the short-wave-pass dichroic mirror is used to separate the OCT imaging light beam and the eye reflection light, and the long-wave-pass dichroic mirror is used to separate the induced light and the eye reflection light.

[0005] The device further comprises an induced display located below the long-wave-pass dichroic mirror, an OCT sample arm electrically controlled lifting module and an OCT light path channel located directly below the short-wave-pass dichroic mirror; specifically, the OCT light path channel comprises, in sequence from bottom to top, a collimating mirror, a two-dimensional galvanometer system and an OCT light path correction module, and the OCT sample arm electrically controlled lifting module is used to drive the OCT light path channel to move up and down. The induced display is used to induce the line of sight of the eyes. The OCT light path channel is used to control the OCT imaging light beam to become a scanning state and transmit the OCT imaging light beam to the short-wave-pass dichroic mirror of the central light path channel, and finally transmit the OCT imaging light beam to the eyes.

[0006] Preferably, the annular lamp strip specifically comprises a plurality of annularly and uniformly distributed LED lamp beads, and the LED lamp beads emit infrared light with a waveband of 750nm-950nm.

[0007] Specifically, the cut-off waveband of the short-wave-pass dichroic mirror is 950nm, the short-wave-pass dichroic mirror reflects light with a waveband of 950nm or above and transmits light with a waveband of 950nm or below; the cut-off waveband of the long-wave-pass dichroic mirror is 700nm, the long-wave-pass dichroic mirror reflects light with a waveband of 700nm or below and transmits light with a waveband of 700nm or above.

[0008] Specifically, the receiving waveband of the intermediate infrared camera is 750-950nm; the emitting waveband of the induced display is 400nm-700nm; the emitting waveband of the OCT light source is 1010nm-1110nm; and the receiving waveband of the side infrared camera is 750nm-950nm.

[0009] Specifically, the intermediate optical path correction module one, the intermediate optical path correction module two and the OCT optical path correction module are each composed of two achromatic doublet lenses.

[0010] In another aspect, the application also discloses a method for three-waveband light self-calibration fundus imaging, which is based on the above-mentioned three-waveband light automatic calibration fundus imaging device; the method comprises:

[0011] The annular light belt provides 750nm-950nm infrared ambient light for imaging human face and human eye and is not easy to be disturbed, and forms an annular point diagram in the pupil of the human eye, which is used to assist the pupil calibration of the intermediate camera.

[0012] The human face image and the first human eye image are acquired by the two side infrared cameras, and the three-waveband light automatic calibration fundus imaging device is controlled to reach the preliminary working position according to the human face image and the human eye image; specifically, the mechanical arm is controlled by the device to control the position of the whole device;

[0013] The second human eye image and the annular point diagram are acquired by the intermediate infrared camera through the central optical path channel, and the three-waveband light automatic calibration fundus imaging device is controlled to reach the final working position according to the second human eye image and the annular point diagram; wherein the second human eye image is formed by the infrared ambient light provided by the human eye reflection light belt, and the second human eye image is magnified by the fundus mirror of the central optical path. If the direct entry into the intermediate infrared camera cannot obtain a high-quality image under the ideal field of view, therefore, the human eye reflection light passes through the fundus mirror and then passes through the short-wave pass dichroic mirror without influence, and then passes through the intermediate optical path correction module one for correcting the light beam, and then passes through the intermediate optical path correction module two without influence, and finally is transmitted to the intermediate infrared camera, so as to obtain the human eye image under the ideal field of view and the annular light belt point diagram formed in the pupil.

[0014] The visible light waveband image emitted by the induction display is used to induce the line of sight of the human eye to a specified direction; the visible light emitted by the induction display is reflected into the central optical path channel through the long-wave pass dichroic mirror, and then passes through the intermediate optical path correction module one, the short-wave pass dichroic mirror without influence and the fundus mirror in sequence, and finally reaches the human eye to form the image for guiding the human eye. The angle between the long-wave pass dichroic mirror and the central optical path channel and the LED display for inducing the line of sight of the human eye is 45 degrees, the long-wave pass dichroic mirror allows the infrared waveband absorbed by the intermediate infrared camera to pass through, and reflects the visible light emitted by the induction display for inducing the line of sight of the human eye.

[0015] The OCT sample arm electric control lifting module controls the overall up and down movement of the OCT light path to a position matched with the myopia and hypermetropia degree of the measured person according to the vision condition of the measured object, and the OCT light beam is used to scan and image the fundus of the human eye with the ideal working distance. Specifically, the OCT light source with a light-emitting wave band of 1010nm-1110nm emits parallel light beams after collimating mirrors, the parallel light beams are changed into parallel light beams scanning in a two-dimensional plane through a two-dimensional galvanometer system, and then transmitted to a short-wave-pass dichroic mirror of the central light path after an OCT light path correction module composed of two achromatic doublet lenses; the short-wave-pass dichroic mirror is at an angle of 45 degrees with the central light path and the bottom light path of the OCT, the short-wave-pass dichroic mirror allows the infrared light received by the intermediate infrared camera and the visible light emitted by the induction display for inducing the line of sight of the human eye to pass through, and at the same time reflects the OCT imaging light beam. After being reflected by the short-wave-pass dichroic mirror, the light beam is transmitted to the fundus mirror and finally irradiates the human eye pupil to scan the fundus and obtain the fundus scanning image of the human eye.

[0016] After the above scheme is adopted, the beneficial effects of the present application are: the present application designs the combination and separation of the OCT imaging light path and the human eye calibration light path, solves the cooperation problem of short-distance OCT imaging and accurate alignment of the human eye, and introduces another induction light path on the basis of the above two light paths to guide the human eye and assist in accurately imaging the region of interest on the fundus of the human eye, and at the same time, the OCT sample arm electric control lifting module is used to adjust the distance between the OCT light paths according to the myopia or hypermetropia degree of the measured object, so as to meet the automatic OCT fundus imaging of different vision groups.

[0017] In order to make the above-mentioned purposes and features of the present application more obvious and easy to understand, the following preferred embodiments are described in detail below, and the accompanying drawings are used for description. BRIEF DESCRIPTION OF DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings needed in the embodiments. It should be understood that the following drawings only show some embodiments of the present application, and therefore should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.

[0019] Fig. 1 shows a device structure schematic diagram of a three-waveband light automatic calibration fundus imaging provided by an embodiment of the present application;

[0020] Fig. 2 shows a human face imaging schematic diagram of a double-side infrared camera provided by an embodiment of the present application;

[0021] Fig. 3 shows a 16LED lamp bead ring-shaped lamp strip effect schematic diagram provided by an embodiment of the present application;

[0022] Fig. 4 shows a schematic diagram of the initial calibration effect of the double-side infrared camera according to an embodiment of the present application;

[0023] Fig. 5 shows a schematic diagram of the OCT imaging robot structure according to an embodiment of the present application;

[0024] Fig. 6 shows a schematic diagram of the central light path channel imaging the human eye according to an embodiment of the present application;

[0025] Fig. 7 shows a schematic diagram of the induced light transmission to the human eye according to an embodiment of the present application;

[0026] Fig. 8 shows a schematic diagram of the precise calibration effect on the left eye according to an embodiment of the present application;

[0027] Fig. 9 shows a schematic diagram of the OCT imaging the fundus at a working distance of 50 mm according to an embodiment of the present application;

[0028] Fig. 10 shows a flowchart of the three-waveband light automatic calibration fundus imaging process at a working distance of 50 mm according to an embodiment of the present application.

[0029] Fig. 10 shows a flowchart of the three-waveband light automatic calibration fundus imaging process at a working distance of 50 mm according to an embodiment of the present application. DETAILED DESCRIPTION

[0030] To make the objectives, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be described below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. The components of the embodiments of the present application described and shown in the accompanying drawings can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the claimed present application, but only represents selected embodiments of the present application. Based on the embodiments of the present application, every other embodiment obtained by a person skilled in the art without creative work falls within the scope of the present application.

[0031] First, the application scenarios applicable to the present application are introduced. The robot OCT in the present application is an important link for eye fundus scanning imaging of human eyes for eye diagnosis and treatment of patients. OCT can detect small retinal or optic nerve head lesions, thus providing a sensitive diagnostic means in the early stage of the disease, which is particularly important for early intervention and treatment of eye diseases. For eye diseases that have been diagnosed, OCT scanning can be used to monitor the progression of the disease and evaluate the treatment effect. For example, in the treatment of glaucoma, OCT can help doctors evaluate the changes in the retinal nerve fiber layer thickness, so as to adjust the treatment plan. In ophthalmic surgery, OCT can provide real-time eye structure imaging to help doctors plan and operate the surgery.

[0032] It is found through research that to implement robot OCT imaging with a large field of view, the key is to realize accurate three-dimensional space point tracking of the eyeball pupil and the gaze direction within the working distance range of the OCT robot imaging device, that is, to automatically implement human eye OCT imaging calibration.

[0033] Embodiment 1:

[0034] Based on the above, the embodiments of the present application provide a three-band light automatic calibration fundus imaging device, which solves the coordination problem between the recent OCT robot automatic calibration pupil and OCT imaging at a short distance.

[0035] Please refer to FIG. 5, which is a structural schematic diagram of an OCT imaging robot provided by an embodiment of the present application. As shown in FIG. 5, the OCT imaging robot structure provided by the embodiment of the present application comprises a device control robot arm 13 and a three-band light automatic calibration fundus imaging device 16. The three-band light automatic calibration fundus imaging device is used to obtain image information of a human face, human eyes and eyeball gaze direction, and to realize final OCT imaging. The device control robot arm is used to control the device to move to an ideal working position according to the image information of the human face, human eyes and eyeball gaze direction obtained by the three-band light automatic calibration fundus imaging device.

[0036] Please refer to FIG. 2, which is a schematic diagram of a double-side infrared camera imaging a human face provided by an embodiment of the present application. As shown in FIG. 2, the three-band light automatic calibration fundus imaging device provided by the embodiment of the present application comprises two side infrared cameras 12, which can obtain a public field of view of a human face with a width of 100 mm at an imaging distance of 50 mm.

[0037] Please refer to Fig. 3, which is a schematic diagram of the effect of the ring-shaped light strip 13 attached around the fundus mirror 1 according to an embodiment of the present application. As shown in Fig. 3, the ring-shaped light strip is composed of 16 infrared LED lamp beads evenly distributed around the fundus mirror. In addition to providing infrared ambient light for the human face, the ring-shaped light strip also forms a clear ring-shaped point pattern in the human eye 14, which is used to obtain the eye gaze direction to assist in pupil calibration.

[0038] Please refer to Fig. 4, which is a schematic diagram of the effect of initial calibration of the double-side infrared camera according to an embodiment of the present application. As shown in Fig. 4, the double-side infrared camera according to an embodiment of the present application can obtain images of almost the entire human face and the complete images of both eyes at the initial calibration position.

[0039] Please refer to Fig. 1, which is a schematic diagram of the structure of a three-waveband light automatic calibration fundus imaging device according to an embodiment of the present application. As shown in Fig. 1, the three-waveband light automatic calibration fundus imaging device according to an embodiment of the present application includes a central light path channel, which includes a fundus mirror 1, a short-wave pass dichroic mirror 2, an intermediate light path correction module 1 3, a long-wave pass dichroic mirror 4, an intermediate light path correction module 2 5, and an intermediate infrared camera 6 arranged in sequence. Two side infrared cameras 12 are symmetrically arranged on both sides of the short-wave pass dichroic mirror 2, and the two side infrared cameras 12 are at a certain placement angle with the central light path channel and face the front of the fundus mirror 1. The front end of the fundus mirror 1 is provided with a ring-shaped light strip 13. The planes of the short-wave pass dichroic mirror 2 and the long-wave pass dichroic mirror 4 are at an angle of 45° with the light paths of other components in the central light path channel. Specifically, the placement angle between the two side infrared cameras 12 and the central light path channel is 25-35 degrees, and the placement angle according to the embodiment is 30 degrees.

[0040] The device further includes an induction display 7 located at the side of the long-wave pass dichroic mirror 4, an OCT sample arm electric control lifting module 11, and an OCT light path channel located below the short-wave pass dichroic mirror 2. The OCT light path channel includes a collimating mirror 8, a two-dimensional galvanometer system 9, and an OCT light path correction module 10 arranged in sequence from bottom to top. The OCT sample arm electric control lifting module 11 is used to drive the OCT light path channel to move up and down.

[0041] The focal length of the fundus mirror 1 is 50 mm, which is used for large field OCT fundus scanning at a working distance of 50 mm.

[0042] The short-wave pass dichroic mirror 2 is located at the central position of the two side infrared cameras and also belongs to a part of the central light path channel, which is used to transmit the 750-950 nm infrared light reflected by the induction light and the human eye, and reflect the OCT imaging light beam with a waveband of 1010-1110 nm.

[0043] Intermediate optical path correction module one is composed of two doublet achromatic lenses with focal length of 75mm, which is used to transmit the image of human eye to the subsequent central optical path and to transmit the induced image emitted by the induced display.

[0044] The long-pass dichroic mirror 4 with cut-off wavelength of 700nm is used to transmit the 750nm-950nm infrared light reflected by human eye, while reflecting the 400nm-700nm visible light image emitted by the induced display 7 for inducing the line of sight of human eye.

[0045] Intermediate optical path correction module two 5 is used to guide the received human eye reflection light to the intermediate infrared camera 6 at a suitable angle and convergence degree.

[0046] The intermediate infrared camera 6 is used to receive the infrared human eye image reflected by human eye and conducted by the central optical path.

[0047] The induced display 7 is used to induce the line of sight of human eye, which emits 400nm-700nm visible light image to guide human eye to look at the specified direction.

[0048] The OCT optical path channel is used to conduct the OCT imaging light beam.

[0049] Please refer to FIG. 6, which is a schematic diagram of the central optical path channel imaging human eye provided by the embodiment of the present application. As shown in FIG. 6, the human eye 14 is used to provide the information source for the calibration of OCT robot. The central optical path channel imaging human eye in FIG. 6 includes:

[0050] The fundus scope 1;

[0051] The short-pass dichroic mirror 2 with cut-off wavelength of 950nm is used to transmit the 400nm-700nm induced light and the 750nm-950nm infrared light reflected by human eye, while reflecting the OCT imaging light beam with wavelength of 1010-1110nm;

[0052] Intermediate optical path correction module one 3;

[0053] The long-pass dichroic mirror 4 with cut-off wavelength of 700nm is used to transmit the 750nm-950nm infrared light reflected by human eye, while reflecting the 400nm-700nm visible light image emitted by the induced display 7 for inducing the line of sight of human eye;

[0054] Intermediate optical path correction module two 5;

[0055] The intermediate infrared camera 6.

[0056] As shown in Fig. 6, the 750nm-950nm ambient light reflected by the human eye 14 passes through the fundus mirror 1, the short-wave pass dichroic mirror 2, the intermediate light path correction module one 3, the long-wave pass dichroic mirror 4 and the intermediate light path correction module two 5 in turn and finally enters the intermediate infrared camera 6.

[0057] Please refer to Fig. 7, which is a schematic diagram of the transmission of induced light to the human eye provided by the embodiment of the present application. As shown in Fig. 7, the induced display 7 for inducing the line of sight of the human eye emits a 400nm-700nm visible light image, which passes through the long-wave pass dichroic mirror 4 with a cutoff wavelength of 700nm, and then passes through the intermediate light path correction module one 3, the short-wave pass dichroic mirror 2 with a cutoff wavelength of 950nm and the fundus mirror 1 in turn to reach the human eye 14 to be observed.

[0058] Please refer to Fig. 8, which is a schematic diagram of the effect of accurate calibration of the left eye provided by the embodiment of the present application. As shown in Fig. 8, at the final working distance of 50mm, the two side infrared cameras 12 can obtain the image of the face and the human eye, and the intermediate infrared camera can obtain the image of the human eye.

[0059] Please refer to Fig. 9, which is a schematic diagram of the OCT imaging of the fundus at a working distance of 50mm provided by the embodiment of the present application. As shown in Fig. 9, the 1010nm-1110nm OCT light source passes through the collimating mirror 8 to irradiate the two-dimensional galvanometer system 9, which becomes a scanning state with the galvanometer system as the focal point, and then passes through the OCT light path correction module 10 composed of two achromatic doublet lenses with focal lengths of 80mm and 150mm respectively, is reflected by the short-wave pass dichroic mirror 2 with a cutoff wavelength of 950nm into the central light path channel, passes through the fundus mirror 1, and finally converges at the position of the pupil of the human eye at 50mm to scan the fundus.

[0060] Embodiment 2:

[0061] The embodiment provides a three-waveband light self-calibration fundus imaging method, and the device of the method is based on the three-waveband light self-calibration fundus imaging device of embodiment 1.

[0062] Please refer to Fig. 10, which is a flow chart of the three-waveband light automatic calibration fundus imaging method provided by the embodiment of the present application at a working distance of 50mm. As shown in Fig. 10, the three-waveband light automatic calibration fundus imaging method provided by the embodiment of the present application comprises:

[0063] S101, the environment light is provided by the ring-shaped light belt 13, and the two side infrared cameras 12 acquire the image information of the face and the human eye of the imaging object at the initial position according to the imaging similar to Fig. 2.

[0064] S102, the device control arm 15 calculates the relative position relationship between the imaged person's head and the device using the initial information obtained by the two side infrared cameras 12, and begins to control the device to reach the preliminary working position (within 10mm from the target position) in real time. During this process, the two side infrared cameras 12 constantly obtain relative position information, and the device control arm 15 knows the process of device movement according to the relative position information.

[0065] S103, the infrared light reflected by the human eye and the surrounding part reaches the intermediate infrared camera 6 through the central light path channel, and the transmission process of the human eye image is shown in FIG. 6. The intermediate infrared camera 6 obtains image information of the human eye at the current position and a ring point image in the pupil.

[0066] S104, the device control arm 15 further calculates the relative position relationship between the imaged person's eye and the device and the eye gaze direction using the human eye image and the ring point image in the pupil obtained by the intermediate infrared camera 6, and begins to control the device to accurately reach the final working position (within 20um from the target position) of 50mm in real time.

[0067] S105, the visible light image of the induction display 7 for inducing the line of sight of the human eye reaches the human eye through part of the central light path channel. The human eye is guided to a specified direction through the induction image, and the eye gaze direction is inhibited from shaking disadvantageously, and finally an effect image as shown in FIG. 8 is obtained.

[0068] S106, according to the vision of the measured object, the OCT sample arm electric control lifting module controls the OCT light path module to move up and down to a position matched with the vision of the measured object, and then the OCT imaging light beam enters the pupil to scan the fundus to realize fundus imaging through the OCT light path channel and part of the central light path channel. The specific transmission process of the light beam is shown in FIG. 9.

[0069] The positions and angles at which the two side infrared cameras 12 are placed satisfy that: within the image field of view obtained by the two side infrared cameras 12, the whole face can be contained at the working distance.

[0070] The specific requirement that the whole face can be contained within the image field of view obtained by the two side infrared cameras 12 is that: most of the image field of view is the face, and in the embodiment, the distance between the edge of the image field of view and the face is 2-3cm.

[0071] The above only describes the preferred embodiments of the present application, and it should be understood that the present application is not limited to the forms disclosed herein, and should not be regarded as excluding other embodiments, but can be used in various other combinations, modifications and environments, and can be modified within the scope of the concepts described herein by the above-mentioned teaching or related technical or knowledge. The modifications and changes made by those skilled in the art without departing from the spirit and scope of the present application shall be within the protection scope of the claims appended to the present application.

Claims

1. A device for three-wavelength light auto-calibration fundus imaging, characterized in that, The device comprises a central light path channel, the central light path channel comprises, in sequence, an eye fundus mirror (1), a short-wave pass dichroic mirror (2), an intermediate light path correction module one (3), a long-wave pass dichroic mirror (4), an intermediate light path correction module two (5), and an intermediate infrared camera (6), wherein two side infrared cameras (12) are symmetrically arranged on both sides of the short-wave pass dichroic mirror (2), and the two side infrared cameras (12) are at a certain placement angle with the central light path channel and face the front of the eye fundus mirror (1); an annular lamp strip (13) is arranged on the front end of the eye fundus mirror (1); the plane of the short-wave pass dichroic mirror (2) and the long-wave pass dichroic mirror (4) is at an angle of 45° with the light path of other components in the central light path channel; Further comprising an induced display (7) below the long-wave pass dichroic mirror (4); Further comprising an OCT sample arm electric control lifting module (11) and an OCT light path channel below the short-wave pass dichroic mirror (2), the OCT light path channel comprises, in sequence from bottom to top, a collimating mirror (8), a two-dimensional galvanometer system (9), and an OCT light path correction module (10), and the OCT sample arm electric control lifting module (11) is used to drive the OCT light path channel to move up and down.

2. The apparatus for three waveband optical auto-calibration fundus imaging according to claim 1, wherein, The annular lamp strip (13) is specifically a plurality of annularly and uniformly distributed LED lamp beads.

3. The device for automatic calibration of fundus imaging with three-band light according to claim 2, characterized in that, The LED lamp beads can emit infrared light with a wave band of 750nm-950nm.

4. The apparatus of claim 1, wherein, The short-wave pass dichroic mirror (2) has a cut-off wave band of 950nm, reflects light above the 950nm wave band and transmits light below the 950nm wave band; the long-wave pass dichroic mirror (4) has a cut-off wave band of 700nm, reflects light below the 700nm wave band and transmits light above the 700nm wave band.

5. The apparatus of claim 1, wherein the apparatus is configured to automatically calibrate the three waveband light to the eye of the subject. The receiving wave band of the intermediate infrared camera (6) is 750-950nm, and the emitting wave band of the induced display (7) is 400nm-700nm.

6. The apparatus of claim 1, wherein, The emitting wave band of the OCT light source is 1010nm-1110nm; the receiving wave band of the side infrared camera (12) is 750nm-950nm.

7. The apparatus of claim 1, wherein the apparatus is configured to automatically calibrate the three waveband light to the eye of the subject. The intermediate light path correction module one (3), the intermediate light path correction module two (5), and the OCT light path correction module (10) are each composed of two achromatic doublet lenses.

8. A method for three-band optical self-calibration fundus imaging, characterized in that, The method is based on the device for automatically calibrating eye fundus imaging of three wave bands of light according to any one of claims 1-7, and the method comprises the following steps: The annular lamp strip (13) provides an infrared ambient light of 750nm-950nm for a human face, so that a ring-shaped point image of the annular lamp strip is generated in the pupil of the human eye; A human face image and a first human eye image are acquired by the two side infrared cameras (12), and the device for automatically calibrating eye fundus imaging of three wave bands of light is controlled to reach a preliminary working position according to the human face image and the human eye image; A second human eye image and the ring-shaped point image are acquired by the intermediate infrared camera (6) through the central light path channel, and the device for automatically calibrating eye fundus imaging of three wave bands of light is controlled to reach a final working position according to the second human eye image and the ring-shaped point image; The visible light wave band image emitted by the induction display (7) is used to induce the human eye to look in a specified direction; The OCT sample arm electric control lifting module (11) controls the overall up and down movement of the OCT light path to a position matched with the myopia and hypermetropia degree of the measured person according to the vision condition of the measured object, and the OCT light beam is used to scan and image the fundus of the human eye with an ideal working distance.

9. The method of claim 8, wherein, The positions and angles at which the two side infrared cameras (12) are placed satisfy that, under the working distance, the images acquired by the two side infrared cameras (12) can contain the whole face in the field of view.

Images