Mobile electronic device for illuminating veins
The mobile electronic device with a tunable light source addresses vein identification challenges by adjusting color temperature for enhanced visibility, ensuring efficient and user-friendly vein illumination.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- GENZYME CORP
- Filing Date
- 2025-11-05
- Publication Date
- 2026-05-15
AI Technical Summary
Existing drug delivery devices face challenges in locating and identifying suitable veins for intravenous injections due to varying skin colors, environmental conditions, and user expertise, leading to inefficiencies and potential errors in administering medicaments, especially for patients with conditions affecting peripheral vessels or those self-administering treatments.
A mobile electronic device with a tunable light source that adjusts correlated color temperature to enhance vein visibility, featuring user-controlled or automated adjustments based on ambient conditions and skin characteristics, allowing for intuitive and precise vein illumination.
Improves vein visibility and contrast by optimizing light source settings for individual skin tones and environments, facilitating easier and more accurate vein identification for injections or infusions.
Smart Images

Figure US2025054161_15052026_PF_FP_ABST
Abstract
Description
[0001] PAT24293-WO-PCT
[0002] Mobile Electronic Device for Illuminating Veins
[0003] Description
[0004] Field
[0005] The present disclosure relates to the field of illuminating veins of a human or animal body and in particular to an electronic device for illuminating veins.
[0006] Background
[0007] Drug delivery devices allowing for multiple discrete or continuous dosing of a required dosage of a liquid medicinal product and further providing administration of such liquid drug to a patient, are as such well known in the prior art. Generally, such devices have substantially the same purpose as that of an ordinary syringe. Some medicaments require administration by way of infusion.
[0008] Patients suffering from certain diseases like, for example, hemophilia or requiring enzyme replacement therapy, have to take regular intravenous (IV) infusions. The infusions often have to be mixed and prepared, sometimes to the specific needs of the patient, (and sometimes a short time before drug administration) which may include reconstitution of the drug powder from multiple vials using an exact amount of sterile liquids like water and / or saline. As this preparation process is typically complex and tedious, it is usually performed by a health care professional in a clinic or pharmacy, potentially using lab equipment.
[0009] After preparation, the resulting infusion must be administered within a limited time frame, as it is often sensitive to environmental factors like elevated heat, light, extended movement or shock. Further, the passage of time may reduce the efficacy of the mixture for other reasons, for example if the mixture is prone to separation or demixing over time. Therefore, patients regularly need to come to health care centers to receive their infusions directly after preparation. Some drugs require infusion with defined flow rates over several hours, so patients have to stay in said clinics for a long time, adding to the travel time and overall inconvenience. This is a huge burden to patients, especially if living far away from a suitable clinic. If they are used to the treatment, capable of handling corresponding user tasks and tolerate it well, patients would prefer to receive their regular infusion at home. Puncturing of a blood vessel or vein for administering of a medicament is sometimes quite challenging. In a first step it may be required to find a suitable vein and insert a respective intravenous needle into it. Even experienced healthcare professionals frequently have trouble locating a blood vessel or vein suitable for intravenous injection, especially if the patient is obese or has certain other preconditions affecting the peripheral vessels. In other scenarios and when patients intend to self-administer a medicament they may often lack the experience to reliably find a vein even if no adverse preconditions are given.
[0010] There have been reported devices to locate a blood vessel, wherein the respective device has to be placed directly on the injection site of the skin for visualization of a blood vessel or vein. Such devices have to be removed before needle-insertion. Therefore, an operator has to remember the blood vessel as previously indicated or retrieved by the device. Thus, a subsequent insertion of a needle may be rather prone to errors.
[0011] An identification and finding of veins suitable for injection or infusion may be quite challenging. Suitable veins may be sometimes non-visibly covered by the overlying tissue or skin of a patient. Moreover, different patients may exhibit different skin color that makes it even more difficult to find a suitable vein underneath the patient skin. Sometimes, the patients or professional caregivers have to deal with various and quite different environmental conditions, particularly in terms of an illumination or ambient light conditions. Such varying conditions may also have a non-neglectable impact on the retrieval and identification of veins that are suitable for injection or infusion.
[0012] It is therefore an object of the present disclosure to provide improvements for manual retrieval and identification of veins suitable for injection or infusion. The improvements should be easily available for users, patients and professional care givers. The improvements should provide a rather easy and failure safe vein retrieval and / or identification and should be easy and intuitive to handle.
[0013] Summary
[0014] In one aspect the present disclosure relates to a mobile electronic device for illuminating veins of a human or animal body. The mobile electronic device comprises a housing. The mobile electronic device further comprises a tunable light source. The tunable light source is arranged or fixed inside the housing or is attached to the housing. The tunable light source is configured to emit illuminating light at a correlated color temperature. The mobile electronic device further comprises a processor or controller inside the housing and coupled to the tunable light source. The processor or controller is operable to adjust the correlated color temperature of the tunable light source. In this way the mobile electronic device provides a tunable light source, which is tunable or adjustable in terms of its color temperature, specifically in terms of a correlated color temperature.
[0015] Experiments have revealed that visibility and detectability of particular veins of a human or animal body can be improved when making use of a suitable correlated color temperature of a light source. Hence, visibility and contrast of particular veins may be better when illuminated with a first correlated color temperature compared to situations in which the puncture site of an animal or human body is illuminated with a second correlated color temperature that distinguishes from the first correlated color temperature. By providing a tunable light source, which is tunable or adjustable at least in terms of a correlated color temperature there can be provided a patient specific or user specific optimal or optimized correlated color temperature of the tunable light source, which when illuminating a puncture site of the human or animal body provides an optimal contrast and / or an optimal visibility of veins of the respective human or animal body that are suitable for puncturing, e.g. for injection or infusion.
[0016] Generally, the color temperature of a light source is a parameter describing the color of visible light sources by comparing it to the color of light emitted by an idealized opaque, non-reflective body. The temperature of the ideal emitter that matches the color most closely is defined as the color temperature of the original visible light source. Color temperature is usually measured in kelvins. The color temperature scale describes only the color of light emitted by a light source, which may actually be at a different (and often much lower) temperature.
[0017] To the extent that a hot surface emits thermal radiation but is not an ideal black-body radiator, the color temperature of the light is not the actual temperature of the surface. An incandescent lamp's light is thermal radiation, and the bulb approximates an ideal black-body radiator, so its color temperature is essentially the temperature of the filament. Thus, a relatively low temperature emits a dull red and a high temperature emits the almost white of the traditional incandescent light bulb.
[0018] Many other light sources, such as fluorescent lamps, or light emitting diodes (LEDs) emit light primarily by processes other than thermal radiation. This means that the emitted radiation does not follow the form of a black-body spectrum. These sources are assigned what is known as a correlated color temperature. Accordingly, the correlated color temperature is the color temperature of a black-body radiator which to human color perception most closely matches the light from the lamp. According to some examples, the mobile electronic device and its tunable light source are particularly configured to illuminate a vein or biological tissue in reflection geometry. Hence, the illuminating light emitted by the tunable light source is particularly configured to illuminate a portion of a human or animal body such that a portion of the illuminating light reflected or scattered by the human or animal body, i.e. reflected illuminating light, can be captured, detected and / or analyzed, e.g., by the human eye, to identify and / or to localize a vein of the human or animal body.
[0019] According to some examples, the tunable light source may be manually tuned by users or patients making use of the mobile electronic device. In this way, the correlated color temperature of the tunable light source may be adapted or adjusted in accordance to the subjective visual perception of a user making use of the mobile electronic device for the purpose of vein illumination and / or vein finding.
[0020] According to some examples, the tunable light source may be automatically or autonomously tuned by the processor of the mobile electronic device, e.g., with respect to at least one of a calibration parameter or on the basis of a surface characterization parameter, e.g., characterizing at least one of a surface, surface texture or surface color of a region of interest of a body of a user or patient.
[0021] According to further examples, the tunable light source is adapted to emit illuminating light with variable light characteristics including variable brightness, variable intensity, variable correlated color temperature, variable focal length and / or variable geometric light propagating characteristics. Hence, the light source may be tunable with respect to many different parameters by way of which the emitted illuminating light can be characterized.
[0022] The tunable light source may provide a variation or tuning of the intensity or brightness of the emitted illuminating light. The tunable light source may also provide a variation or tuning of the color, color composition and / or of the correlated color temperature. The tunable light source may further provide a variation or tuning of the focal length and / or of geometric light propagating characteristics, such as a divergence or convergence of a cone of light emitted by the light source.
[0023] According to a further example, the mobile electronic device comprises an input unit, which is coupled to the processor and which is configured to control or to trigger the processor to adjust the correlated color temperature of the tunable light source. The input unit may be user controllable. This way, the input unit allows a user to manually adjust the correlated color temperature of the tunable light source and / or any of the above-mentioned light characteristics. The input unit may comprise at least one actuating element, which may be actuatable by a user of the mobile electronic device. The actuating element may comprise a button, which is depressible by a user of the mobile electronic device.
[0024] In some examples, the input unit may comprise a first actuating element and a second actuating element. The first and the second actuating element may be actuatable, e.g., movable or depressible by a user to increase the correlated color temperature and / or to decrease the correlated color temperature. According to some examples, a first actuating element may be actuatable by a user, e.g., depressible by a user for increasing the correlated color temperature of the tunable light source. The second actuating element of the input unit may be actuatable or depressible by a user to decrease the correlated color temperature of the tunable light source.
[0025] Likewise, any one of the first and second actuating elements may be actuatable to vary, to tune and / or to calibrate any one of the above-mentioned light characteristics of the tunable light source. The actuating element may at least partially protrude from the housing to a certain extent. The actuating elements of the input unit may comprise a button, which is manually depressible by a user of the mobile electronic device.
[0026] According to a further example, the input unit may be virtually provided and / or emulated on a touch sensitive display of the mobile electronic device. Here, a particular display section, which emulates or represents an actuating element, may be touched by a user for actuation. In still further examples, the input unit may comprise a microphone or the like acoustic sensors by way of which a voice of a user could be received and could be processed as a voice command.
[0027] According to some examples, the input unit comprises at least one actuating element, which may be located outside a touch-sensitive display of the mobile electronic device. Such actuating elements enable and provide a rather intuitive actuation, even a blind or palpable actuation of the respective actuating element, which may be palpable from outside the housing of the mobile electronic device. With such actuating elements the input unit may be operable or actuatable without use of the touch-sensitive sensitive display of the mobile electronic device. In this way, controlling of the correlated color temperature via the input unit can be kept rather simple, intuitive and efficient.
[0028] By way of the input unit a user is given the possibility to adjust and / or to tune the correlated color temperature of the tunable light source individually and instantaneously. Hence, while the tunable light source is actually emitting the illuminating light a user may interact with the input unit to modify, hence to adjust the correlated color temperature while the tunable light source emits the illuminating light. In this way there can be provided a live- and hence rather instantaneous feedback to the operator or user of the mobile electronic device in order to find or to identify an optimum correlated color temperature that complies with the subjective visual perception of the user or patient while making use of the mobile electronic device for illuminating veins.
[0029] According to a further example, the mobile electronic device comprises an electronic memory, which is configured to store numerous light source setting. The numerous light source settings distinguish by at least one of the correlated color temperature of the tunable light source and an intensity of the illuminating light emitted by the tunable light source. The electronic memory is configured to store numerous different light source settings. Any of the stored light source settings may be then selectable by a user, e.g., via the input unit to tune or to adjust the tunable light source in accordance to the light source settings.
[0030] Hence, a first light source setting may define a first correlated color temperature and / or a first intensity of the illuminating light. A second light source setting may define a second correlated color temperature and / or a second intensity of the illuminating light of the tunable light source.
[0031] The processor may provide a variety of different light source settings, from which the user may select at least one. When selected by a user, e.g. via the input unit, the processor is operable to drive or to control operation of the tunable light source such that the illuminating light emitted by the tunable light source corresponds to the selected light source setting. In this way predefined light sources settings can be stored in the electronic memory and can be selected on demand. In this way, a user may be given the possibility to define numerous different light source settings, which may represent an optimum correlated color temperature and / or an optimum intensity for different ambient conditions.
[0032] Hence, a first light source setting may be particularly suitable or may provide a maximum visibility in rather bright ambient conditions. A second light source setting may provide optimum visibility of illuminated veins in rather dark ambient conditions. Depending on the ambient conditions the user may then select at least one of the light source settings to appropriately adjust the tunable light source in accordance to the momentarily given ambient conditions.
[0033] Moreover, the configuration and storing of numerous different light source settings may be also suitable to adapt the illuminating light of the tunable light source to different skin colors or different skin pigmentation of different patients. Here, a first patient with a first characteristic skin color or skin pigmentation may require a first correlated color temperature and / or first intensity of the illuminating light for providing an optimum visibility of illuminated veins. A second patient with a second skin pigmentation may require a second, and hence a different correlated color temperature and / or intensity of the illuminating light to obtain a maximum visibility or contrast of illuminated veins.
[0034] Individually defining numerous different light source settings and the possibility to store such light source settings in the electronic memory allows to quickly and deterministically adjust or tune the tunable light source to different scenarios of use.
[0035] Hence, different users characterized by different skin pigmentation and requiring different correlated color temperatures of the tunable light source may quickly adjust the tunable light source by simply selecting a suitable light source setting that has been previously stored in the electronic memory of the mobile electronic device.
[0036] According to a further example, of the mobile electronic device the processor is configured to select a light source setting from the electronic memory and to control operation of the tunable light source on the basis of the selected light source setting. The processor may further provide a switching between different predefined or previously stored light sources settings, e.g., during operation of the tunable light source.
[0037] Hence, in some examples, the processor may be operable to switch between different light source settings while the tunable light source is driven or operated by the processor and generates and / or to emits illuminating light.
[0038] In further examples, the processor may also provide a modification of a light source setting, e.g. in terms of the correlated color temperature and / or in terms of the intensity of the emitted illuminating light. A modified light source setting, which may be modified through the input unit may be then stored as a new or as a further light source setting. In this way, the user is given the possibility to slightly adapt or to slightly modify a given predefined light source setting and to store the modified light source setting as a modified or as a new light source setting in the electronic memory.
[0039] According to some examples, the processor is configured or operable to maintain the correlated color temperature of the tunable light sows over time. Accordingly, the tunable light source and the processor may be configured to adjust the correlated color temperature to a predefined or user- selectable value and to maintain the predefined or user-selected value of the correlated color temperature over time. According to some examples, the processor is configured to control or to operate the tunable light source in a continuous mode, in which the correlated color temperature of the tunable light source remains constant, i.e. , does not change.
[0040] In another example, the processor is further configured to adjust the correlated color temperature of the tunable light source as defined by an operation of the input unit and / or to store a current setting of the tunable light source as a light source setting in the electronic memory. In this way, the mutual interaction between the input unit, the processor or controller and the tunable light source provides an individual control, modification or adjustment of the tunable light source and to store the adjustment of the tunable light source and a light source setting in the electronic memory. At a later use the user is then given the possibility to load or to select such a light source setting from the electronic memory and to directly operate the tunable light source with the stored and / or selected light source setting.
[0041] In a further example, the correlated color temperature of the tunable light source is continuously adjustable. It may be adjustable from rather cool of bluish color temperatures, e.g. around 5,000 K towards the warmer color temperatures, e.g. around 2,000 K, around 2,500 K and / or around 3,000 K. The color temperature of the tunable light source may be continuously and / or steplessly adjustable. This provides a rather easy and precise tuning of the color temperature of the tunable light source in order to obtain a correlated color temperature that matches best with the given conditions in terms of ambient illumination and / or terms of skin color or skin pigmentation.
[0042] In further examples, the electronic memory may store a predefined light source setting, which is particularly suitable for patients with a particular skin color or skin pigmentation. For selecting or preselecting a suitable light source setting the mobile electronic device may be configured to provide one or a number of predefined light source settings that are likely to match with a particular skin color of skin pigmentation. In some examples, the user may select one particular skin color or skin pigmentation and may obtain a reduced number of suitable light source settings from which the user may further select.
[0043] Moreover, and according to some examples, the tunable light source may be tunable around a correlated color temperature of about 3,300 K. With further examples, the tunable light source may be tunable around a correlated color temperature of about 4,000 K. In further examples, the tunable light source is tunable around a correlated color temperature of about 4,700 K. In further examples, the tunable light source is tunable around a correlated color temperature of about 5,400 K. Here, the user may conduct a preselection among a variety of pre-selectable correlated color temperatures, e.g., of about 3,300 K, 4,000 K, 4,700 K and 5,400 K. Ater having selected one of the afore mentioned correlated color temperatures, the user may be then given the possibility to conduct a manual fine-tuning of fine adjustment of the correlated color temperature by making use of the input unit. Here, the user may conduct a fine-tuning in a range of up to + / - 350 K with a step size of less than 10 K, less than .20 k or less than 50 K.
[0044] According to a further example of the mobile electronic device, the housing of the mobile electronic device comprises a front side and a backside. The backside is located opposite to the front side. The tunable light source is provided on one of the front side and the backside. In some examples, there may be even provided a first tunable light source and a second tunable light source. Here, the first tunable light source may be provided on the front side and the second tunable light source may be provided on the backside of the housing of the mobile electronic device.
[0045] The mobile electronic device may comprise a portable electronic device, such as a smart phone, a tablet computer or a smart watch. In some examples, the front side of the housing may be provided with a two-dimensional display, such as a touch sensitive display. The backside of the housing may be void of a display. It may comprise or may be provided with a light source, e.g. with the tunable light source and / or with a backside camera or camera lens.
[0046] Also, the front side may be provided with a front camera or front camera lens. It may be also provided with an ambient light sensor.
[0047] According to some examples, at least one of the front camera and the backside camera may comprise or may operate as an ambient light sensor. Hence, an image derivable from at least one of the front camera and the backside camera may be analyzed, e.g., by the processor of the mobile electronic device to derive or to determine ambient light conditions.
[0048] With further examples, any one of the cameras of the mobile electronic device may be operable to capture an image of a region of interest of a body of a user or patient. The respective image may be subject to image analysis, e.g., in order to derive a surface characterization parameter by way of which the region of interest of the body of the user can be qualitatively and / or quantitatively characterize. Based on such a surface characterization parameter the processor may be operable to tune the tunable light source.
[0049] In some examples, the housing of the mobile electronic device may be of cubic shape. It may comprise a planar front side and a rather planar backside. The front side and the backside may be arranged or oriented substantially parallel to each other. The front side and the backside may be mutually connected through or via a sidewall. The sidewall may be of a somewhat rectangular cross section. It may mutually connect outer edges of the front side and the backside, which may be somewhat equal in size.
[0050] According to a further example of the mobile electronic device, the housing comprises the sidewall provided with at least one user actuatable actuating element connected to the processor in order to adjust at least one of an intensity and the correlated color temperature of the tunable light source. Moreover, the user actuatable actuating element may be configured to tune or to modify at least one of the light characteristics of the tunable light source. The at least one user actuatable actuating element may be implemented as a part of the input unit. There may be provided one user actuatable actuating element on one lateral side of the sidewall of the housing.
[0051] There may be provided even a second user actuatable actuating element at the same side or at an opposite side of the sidewall of the housing. It may be further provided that there are altogether at least three user actuatable actuating elements, which are integrated or arranged at or in the sidewall of the housing. Here, one lateral side of the sidewall may be provided with two user actuatable actuating elements. An opposite side of the sidewall may be provided with one user actuatable actuating elements. By way of the user actuatable actuating elements at least one of the correlated color temperature and the intensity of the illuminating light emitted by the tunable light source can be adjusted and / or controlled by the user, e.g., by depressing or actuating at least one of the user actuatable actuating elements.
[0052] With numerous user actuatable actuating elements, a variety of different light characteristics can be tuned or modified through user interaction. Here, a first user actuatable actuating element may be configured to vary or to tune at least one light characteristics, e.g., at least one of a brightness, an intensity, a correlated color temperature, a focal length or a geometric light propagation characteristics of the tunable light source. A second user actuatable element may be configured to vary or to tune at least another one light characteristics, e.g., at least another one of the brightness, the intensity, the correlated color temperature, the focal length or the geometric light propagation characteristics of the tunable light source. Likewise and with a third user actuatable element, a further light characteristics can be modified accordingly.
[0053] Providing of user actuatable actuating elements in or on the sidewall of the housing is of particular benefit since the light source provided on one of the front side and the backside of the housing may in a well-defined orientation with regard to the illumination site of the human or animal body while the user actuates the respective user actuatable actuating element. For this, the user does not have to visually inspect a display as provided on the front side. Neither will the user have to inspect the light source as provided on the backside of the housing.
[0054] Rather, the user may orient the mobile electronic device with its tunable light source towards the illumination site of a skin portion of the patient and may simply adjust at least one of the intensity and the correlated color temperature by operating or actuating at least one of the user actuatable actuating element, while keeping the orientation of the mobile electronic device rather constant.
[0055] In some examples, the user actuatable element as provided on the same or on opposite sides of the sidewall of the housing may be user actuatable by a thumb, by an index finger and / or by a middle finger of a user's hand actually holding the mobile electronic device. This provides a rather intuitive and easy handling of the mobile electronic device and the way the tunable light source can be tuned or adjusted.
[0056] According to a further example, the mobile electronic device comprises a two-dimensional display with a two-dimensional array of pixels. The two-dimensional display may be touch sensitive and may thus comprise a two-dimensional touch sensitive display. The two-dimensional touch sensitive display may comprise a matrix of pixels by way of which the touch sensitive display may illustrate numerous information or commands to a user. The two-dimensional touch sensitive display may be further configured to emulate at least one or numerous actuating elements on the display, which when touched by a user on the touch sensitive display are suitable to instruct the processor to tune or to adjust the settings, i.e. , at least one light characteristics, such as, one of the correlated color temperature and the intensity of the tunable light source.
[0057] For instance, there may be provided a shiftable, movable and / or rotatable regulator on the two- dimensional touch sensitive display, which allows for a rather intuitive tuning or adjusting of at least one of the correlated color temperature and the intensity of the tunable light source. The shiftable, movable and / or rotatable regulator may be emulated on the touch sensitive display.
[0058] According to a further example, the tunable light source is integrated into the two-dimensional touch sensitive display. Hence, the display itself may be operable to generate and to emit the illuminating light at the correlated color temperature for illuminating veins of the human or animal body. It may be provided that the entirety of the touch sensitive display acts as a tunable or as the tunable light source. In this way there can be provided a rather large light source having a comparatively large extent in the transverse direction, i.e. in the direction perpendicular to the propagation direction of the emitted illuminating light.
[0059] By way of a comparatively large tunable light source there can be provided a comparatively large and homogeneously illuminated region or region of interest of the body of the user or patient, e.g., on the skin of the human or animal body for vein illumination. The comparatively large scaled tunable light source as provided by the touch sensitive display is particularly configured to provide a rather homogeneous cone of light or beam of light, which has a constant color temperature as well as a rather constant light intensity in transverse direction. This may be beneficial for a rather homogeneous and well-defined vein illumination of the human or animal body.
[0060] Specifically and in combination with the integration of the tunable light source into the two- dimensional touch sensitive display it may be of benefit, to enable a tuning or adjusting of the tunable light source by way of user actuatable actuating element(s), which may be electro- mechanically implemented in or on the sidewall of the housing of the mobile electronic device. Here, the rather bright and homogeneously illuminated display of the mobile electronic device may be directed to the skin portion of the human or animal body that needs to be visually inspected. While the light source is oriented towards the skin portion the user is given the possibility to modify at least one of the correlated color temperature and the intensity of the illuminating light that is emitted via the display of the mobile electronic device.
[0061] According to a further example, the touch sensitive display is a color display and is configured to generate the illuminating light across a major part of its display surface. In some examples, the entirety of the display surface may be illuminated and may serve as the tunable light source. In some examples, the entirety or almost the entirety of the two-dimensional touch sensitive display may contribute to the tunable light source or may constitute the tunable light source.
[0062] In this way, there can be provided a rather large scaled and brightly shining light source of a mobile electronic device. Here, the display of the mobile electronic device may provide a two-fold function. It may serve as a conventional touch sensitive display of the mobile electronic device, e.g. of a smart phone, of a smartwatch or of a tablet computer. When switching the mobile electronic device into a vein illumination mode the entirety or at least a major part of the surface of the display may provide or may contribute to the tunable light source for vein illumination. Typically, and since the touch sensitive display is a color display it's correlated color temperature can be rather easily adjusted, e.g. by suitable software generated display driving commands. When and during activation of the vein illumination mode the touch sensitive display may be inactive and may be insensitive to any further user commands. It may be provided that the light source settings are individually or manually controlled via the user input located outside the touch sensitive display. Here, at least one user actuatable actuating element provided in or on the sidewall of the housing of the mobile electronic device may be configured to manually adjust or to manually tune the tunable light source when in the vein illumination mode. In addition, the adjustment of the tunable light source by be conducted by voice commands, which may be appropriately processed by the input unit and / or processor.
[0063] In the same way at least one of the user actuatable actuating element or voice command may be operable to terminate the vein illumination mode and to return the mobile electronic device into a conventional or standard operation mode, in which the touch sensitive display provides information to the user and in which the touch sensitive display is configured to receive user commands by touching various or selected portions on the display surfaces.
[0064] According to a further example, the tunable light source comprises a multicolor LED or numerous LED light sources of different color, which can be appropriate driven or tuned to provide an adjustable correlated color temperature over a comparatively large scale. The LED light sources may be provided on the display or may be integrated into the touch sensitive display on the front side of the housing of the mobile electronic device. With further examples, the LED light source or numerous LED light sources may be provided on or may be integrated into the backside of the housing of the mobile electronic device.
[0065] According to a further example, the mobile electronic device comprises an ambient light sensor, which is coupled to the processor. The ambient light sensor is configured to capture ambient light. At least one of the ambient light sensor and the processor is configured to measure at least one of an intensity and a spectral composition of ambient light captured by the ambient light sensor. In further examples, at least one of the ambient light sensor and the processor is configured to measure both, an intensity and a spectral composition of ambient light that is captured by the ambient light sensor.
[0066] With further examples, the processor and / or the tunable light source is or are configured to adjust or to tune at least one of the correlated color temperature and an intensity of the illuminating light emitted by the tunable light source on the basis of the ambient light captured by the ambient light sensor. Specifically, the intensity and / or the spectral composition of the ambient light as a captured by the ambient light sensor is used to adjust or to tune at least one of the correlated color temperature of the tunable light source and the intensity of the illuminating light emitted by the tunable light source.
[0067] In this way, momentary ambient light conditions can be captured and quantitatively analyzed at least with regards to their spectral composition and intensity. In accordance to the ambient light, the tunable light source can be tuned or adjusted so as to provide a rather well-defined illumination of a body portion for the purpose of vein illumination of the human or animal body.
[0068] According to some examples, the ambient light sensor may be provided by a camera, e.g., by a front camera and / or by a backside camera of the mobile electronic device. Also, the function of an ambient light sensor may be integrated into such a camera.
[0069] According to a further example, the processor is configured to adjust at least one light characteristics of the illuminating light, such as an intensity of the illuminating light and the correlated color temperature of the illuminating light emitted by the tunable light source via the processor on the basis of at least one of an intensity and a spectral composition of the ambient light as captured by the ambient light sensor. The ambient light control or adjustment of the tunable light source may be provided rather instantaneously, even when the tunable light source is in the course of emitting illuminating light. In this way, at least one of the intensity and the correlated color temperature of the illuminating light emitted by the tunable light source can be rather promptly and instantaneously adjusted in accordance to varying ambient light conditions.
[0070] According to another example, the processor is further configured to adjust at least one of the intensity and the correlated color temperature of the tunable light source to keep a superposition of the emitted illuminating light and the ambient light within rather constant or at least within a predefined margin. In this way, the processor may be operable to compensate varying ambient light conditions by appropriately or complementarily adjusting operation of the tunable light source.
[0071] In some examples, the processor may be configured to reduce the intensity of the illuminating light as emitted by the tunable light source in response to the ambient light sensor registering or detecting an increase of the intensity of the ambient light. Likewise the processor may be configured to increase the intensity of the illuminating light as emitted by the tunable light source in response to the ambient light sensor registering or detecting a decrease of the intensity of the ambient light.
[0072] In the same or like manner the processor or controller of the mobile electronic device may be also configured to vary or to modify the correlated color temperature of the tunable light source in response to a variation of the measurable spectral composition of the ambient light. In this way the sensor and / or the tunable light source as well as the ambient light sensor may interact so as to provide rather homogeneous and constant and / or predefined illumination conditions for illuminating veins of a human or animal body.
[0073] According to further examples, the processor or controller of the mobile electronic device may be also configured to vary or to modify the focal length and / or the geometric light propagating characteristics of the illuminating light emitted or to be emitted by the tunable light source. Here, a spatial divergence or spatial convergence of a cone of light emitted by the tunable light source can be varied on the basis of the ambient light conditions.
[0074] According to some examples, the ambient light sensor is integrated into the two-dimensional display of the mobile electronic device. In other examples, the ambient light sensor may be located outside the display of the mobile electronic device. According to some examples, the ambient light sensor is implemented or integrated in the front side of the housing. In other examples, the ambient light sensor is located or integrated in the backside of the housing. With some examples, the ambient light sensor is located or integrated into that one of the front side and the backside of the housing, which is opposite to the front side or backside, which front side or backside is equipped with the tunable light source.
[0075] With further examples, there may be provided two ambient light sensors. One ambient light sensor may be provided on or integrated into the front side of the housing of the mobile electronic device and another ambient light sensor may be provided on or integrated into the backside of the housing of the mobile electronic device. Also here, the ambient light sensors may be integrated or provide by respective cameras.
[0076] In this way, the ambient light sensor may face away from the illuminated region of the human or animal body and may face towards an ambient light source, such as the sunlight or window light when inside a building while the at least one tunable light source faces towards the illumination site of the human or animal body that is provided with veins to be illuminated and / or punctured.
[0077] According to a further example, the mobile electronic device comprises a camera coupled to the processor and configured to capture an image of a region of interest of the body of a user or patient. In some examples, and when the mobile electronic device is also equipped or provided with a display, an image to be captured by the camera can visualized, e.g., in real time, on the display of the mobile electronic device.
[0078] According to another example, the processor of the mobile electronic device is configured to derive a surface characterization parameter, which is indicative of at least one of a surface texture and a surface color of the region of interest, e.g., of a particular region of a body of a user or patient, such as an injection site of the body.
[0079] The surface characterization parameter may be obtained by digital image analysis of an image captured by the camera of the mobile electronic device. Digital image analysis may be provided by the processor of the mobile electronic device. On the basis of digital image analysis at least one or several surface characterization parameters of the surface of the region of interest, e.g., of a particular region of the body of the user or patient can be obtained. The surface characterization parameter may be indicative of at least one of a skin color and a surface texture of the skin of the body of the user of patient.
[0080] Different surface characteristics, e.g. characterized by the surface characterization parameter, may require different types of illumination, which distinguish by their correlated color temperature or which distinguish by other light characteristics, such as brightness, intensity, focal length or geometric light propagating characteristics.
[0081] According to a further example, the processor of the mobile electronic device is further configured to adjust at least one of an intensity of the illuminating light and the correlated color temperature of the illuminating light on the basis of the surface characterization parameter, e.g., derived from an image taken or captured by the camera, which image may be indicative of an injection site of the body of the user or patient.
[0082] In a further example, the processor of the mobile electronic device is operable to process the image of a region of interest to at least one of extracting or recognizing a structure of interest in the captured image. A region of interest may characterize a certain portion of a body of the patient or user. A structure of interest may characterize a particular blood vessel or vein, which is intended to become punctured, e.g., for the purpose of conducting an injection or infusion procedure.
[0083] According to a further example, the processor may be further operable to visualize at least one of the region of interest and / or of a structure of interest on a display of the mobile electronic device.
[0084] By capturing an image of a region of interest with a camera and by digital image analysis of the captured image there may be derived at least one surface characterization parameter on the basis of which the processor of the mobile electronic device may start to tune the tunable light source, e.g., with respect to at least one of the above-mentioned light characteristics.
[0085] Here, and by tuning the light source, e.g., with respect to the correlated color temperature a particular structure of interest, such as a vein or a particular blood vessel may become visible or the visibility of such a structure of interest may be improved. Hence, the brightness or contrast of the structure of interest may enhance either for a direct visual inspection of the user or patient and / or in the image captured by the camera and reproduced or visualized on the display of the mobile electronic device.
[0086] According to some examples, the processor may be further configured to select a light source setting from the electronic memory and / or to control operation of the tunable light source on the basis of the surface characterization parameter, which is derivable from the captured image of the region of interest of the body of the patient or user.
[0087] Accordingly, the mobile electronic device may be configured to autonomously adjust and / or to tune at least one light characteristics of the tunable light source on the basis of at least one of the ambient conditions and the surface characterization parameter obtained by visual inspection of a region of interest of the body of the user or patient.
[0088] According to a further example, the mobile electronic device comprises one of a smartwatch, a smart phone and a tablet computer. The mobile electronic device may be implemented as a portable electronic device and / or as a wearable electronic device. The mobile electronic device may be obtained by a software application or software app implemented or installed in one of the smartwatch, the smart phone and the tablet computer. In this way a conventional smartwatch, a smart phone and / or a tablet computer already in possession of a user of patient may turn into the mobile electronic device as described herein provided that the mobile electronic device comprises a suitable and hence tunable light source.
[0089] The tunability of the light source may be purely software implemented. Here, a user may be provided with a mobile app by way of which the mobile electronic device can be turned into a vein illumination mode. With the respective software application or app the uses further given the possibility to individually adjust or to individually control the operation of the tunable light source in the vein illumination mode.
[0090] In another aspect the present disclosure also relates to a method of illuminating veins of a human or animal body. The method comprises the steps of using a mobile electronic device comprising a housing, a tunable light source inside or attached to the housing and further comprising a processor inside the housing, which is coupled to the tunable light source. The method further comprises the step of emitting illuminating light by the tunable light source and adjusting the correlated color temperature of the tunable light source. Adjusting or tuning of the correlated color temperature may be user-controlled.
[0091] In some examples, adjusting and / or tuning of the correlated color temperature of the tunable light source may imply selecting a predefined light source setting as stored in a memory of the mobile electronic device.
[0092] According to further examples, the method of illuminating veins of a human or animal body as described herein can be conducted by making use of a mobile electronic device as described above. Insofar, all features, effects and benefits as described above in connection with the mobile electronic device equally apply to the method of illuminating veins of the human or animal body; and vice versa.
[0093] According to another aspect the present disclosure further relates to a computer program for a mobile electronic device to illuminate veins of the human or animal body. The computer program comprises computer readable instructions, which when executed by a processor of the mobile electronic device cause a tunable light source of the mobile electronic device, which is coupled to the processor and / or controlled by the processor to emit illuminating light and to adjust the correlated color temperature of the tunable light source.
[0094] In some examples, the computer program is particularly suitable to execute the above described method of illuminating veins of a human or animal body and / or to operate a mobile electronic device for illuminating veins as described above. Insofar, all features, effects and benefits as described above in connection with any one of the mobile electronic device and the method of illuminating veins equally apply to the computer program for a mobile electronic device; and vice versa.
[0095] In another aspect the present disclosure also relates to a portable patient care kit comprising a holder for a mobile electronic device, wherein the holder comprises a mount for mounting the mobile electronic device in a pre-defined configuration and / or orientation to the holder. The portable patient care kit may further comprise the mobile electronic device, which can be mounted to the holder to keep the mobile electronic device in a predefined configuration or orientation relative to a body portion of a user intended for vein puncturing. By way of the holder there can be provided an efficient one-handed or single-handed use for puncturing of the vein.
[0096] In some examples, the portable patient care kit is equipped with a mobile electronic device as described above, which provides an adjustment of at least the correlated color temperature of a light source thereof for the purpose of an optimal vein illumination.
[0097] According to a further example, the holder comprises a first leg and a second leg pivotally attached to the first leg and pivotable between an initial configuration and a deployed configuration, wherein in the deployed configuration the first leg and the second leg define a planar bottom surface on which the holder can be placed on an even support face. By way of the two legs, the holder can be reconfigured between a rather compact configuration for storage and a deployed configuration for use and / or for holding of the mobile electronic device in a well-defined orientation as a light source for vein illumination.
[0098] According to a further example, the first leg and the second leg of the holder each comprise a notch or a receptacle to receive at least a portion of the housing of the mobile electronic device. In this way, and specifically when in the deployed configuration the receptacles or notches of first and second legs may be separated by a well-defined distance, which distance may be defined by the relative angle between the first and the second legs. When in the deployed configuration the first and second notches of first and second legs may be configured to receive at least a portion of a sidewall of the housing of the mobile electronic device, thereby firmly holding the mobile electronic device in a particular and hence well-defined upright or beveled configuration.
[0099] According to a further example, a side edge of one of the receptacles or notches extends at a predefined beveled angle to keep the housing of the electronic device in a predefined holding angle with respect to the elongation of the first or second leg. In this way there may be provided a slightly downward facing or a particular top to bottom orientation of the light source of the mobile electronic device when duly arranged or fixed inside the receptacles or notches of first and second legs, respectively.
[0100] According to a further example, there is provided a portable patient care kit comprising a housing. The housing comprises a first housing component and a second housing component movably connected to the first housing component. The housing is reconfigurable between a closed configuration and a configuration of use by moving the second housing component relative to the first housing component. The patient care kit further comprises a holder as described above. The holder is connected to or connected to any one of the first and the second housing components and is configured to hold a portable electronic device in a predefined configuration or orientation.
[0101] According to a further example, the holder for the mobile electronic device is pivotably attached to at least one of an inside of the first housing component, an inside of the second housing component and an inside of an intermediate section located between the first housing component and the second housing component via a hinge, in this way, the holder can be pivoted a variably mounted to any of the first housing component, the second housing component and the intermediate section of the housing of the portable patient care kit. This provides a maximum flexibility for using the holder in combination with the portable patient care kit.
[0102] Generally, the scope of the present disclosure is defined by the content of the claims. The disclosure is not limited to specific embodiments or examples but comprises any combination of elements of different embodiments or examples. Insofar, the present disclosure covers any combination of claims and any technically feasible combination of the features disclosed in connection with different examples or embodiments.
[0103] The terms “drug” or “medicament” are used synonymously herein and describe a pharmaceutical formulation containing one or more active pharmaceutical ingredients or pharmaceutically acceptable salts or solvates thereof, and optionally a pharmaceutically acceptable carrier. An active pharmaceutical ingredient (“API”), in the broadest terms, is a chemical structure that has a biological effect on humans or animals. In pharmacology, a drug or medicament is used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being. A drug or medicament may be used for a limited duration, or on a regular basis for chronic disorders.
[0104] As described below, a drug or medicament can include at least one API, or combinations thereof, in various types of formulations, for the treatment of one or more diseases. Examples of API may include small molecules having a molecular weight of 500 Da or less; polypeptides, peptides and proteins (e.g., hormones, growth factors, antibodies, antibody fragments, and enzymes); carbohydrates and polysaccharides; and nucleic acids, double or single stranded DNA (including naked and cDNA), RNA, antisense nucleic acids such as antisense DNA and RNA, small interfering RNA (siRNA), ribozymes, genes, and oligonucleotides. Nucleic acids may be incorporated into molecular delivery systems such as vectors, plasmids, or liposomes. Mixtures of one or more drugs are also contemplated. The drug or medicament may be contained in a primary package or “drug container” adapted for use with a drug delivery device. The drug container may be, e.g., a cartridge, syringe, reservoir, or other solid or flexible vessel configured to provide a suitable chamber for storage (e.g., short- or long-term storage) of one or more drugs. For example, in some instances, the chamber may be designed to store a drug for at least one day (e.g., 1 to at least 30 days). In some instances, the chamber may be designed to store a drug for about 1 month to about 2 years. Storage may occur at room temperature (e.g., about 20°C), or refrigerated temperatures (e.g., from about - 4°C to about 4°C). In some instances, the drug container may be or may include a dual-chamber cartridge configured to store two or more components of the pharmaceutical formulation to-be- administered (e.g., an API and a diluent, or two different drugs) separately, one in each chamber. In such instances, the two chambers of the dual-chamber cartridge may be configured to allow mixing between the two or more components prior to and / or during dispensing into the human or animal body. For example, the two chambers may be configured such that they are in fluid communication with each other (e.g., by way of a conduit between the two chambers) and allow mixing of the two components when desired by a user prior to dispensing. Alternatively or in addition, the two chambers may be configured to allow mixing as the components are being dispensed into the human or animal body.
[0105] The drugs or medicaments contained in the drug delivery devices as described herein can be used for the treatment and / or prophylaxis of many different types of medical disorders. Examples of disorders include, e.g., diabetes mellitus or complications associated with diabetes mellitus such as diabetic retinopathy, thromboembolism disorders such as deep vein or pulmonary thromboembolism. Further examples of disorders are acute coronary syndrome (ACS), angina, myocardial infarction, cancer, macular degeneration, inflammation, hay fever, atherosclerosis and / or rheumatoid arthritis. Examples of APIs and drugs are those as described in handbooks such as Rote Liste 2014, for example, without limitation, main groups 12 (anti-diabetic drugs) or 86 (oncology drugs), and Merck Index, 15th edition.
[0106] Examples of APIs for the treatment and / or prophylaxis of type 1 or type 2 diabetes mellitus or complications associated with type 1 or type 2 diabetes mellitus include an insulin, e.g., human insulin, or a human insulin analogue or derivative, a glucagon-like peptide (GLP-1), GLP-1 analogues or GLP-1 receptor agonists, or an analogue or derivative thereof, a dipeptidyl peptidase-4 (DPP4) inhibitor, or a pharmaceutically acceptable salt or solvate thereof, or any mixture thereof. As used herein, the terms “analogue” and “derivative” refers to a polypeptide which has a molecular structure which formally can be derived from the structure of a naturally occurring peptide, for example that of human insulin, by deleting and / or exchanging at least one amino acid residue occurring in the naturally occurring peptide and / or by adding at least one amino acid residue. The added and / or exchanged amino acid residue can either be codable amino acid residues or other naturally occurring residues or purely synthetic amino acid residues. Insulin analogues are also referred to as "insulin receptor ligands". In particular, the term ..derivative” refers to a polypeptide which has a molecular structure which formally can be derived from the structure of a naturally occurring peptide, for example that of human insulin, in which one or more organic substituent (e.g. a fatty acid) is bound to one or more of the amino acids. Optionally, one or more amino acids occurring in the naturally occurring peptide may have been deleted and / or replaced by other amino acids, including non-codeable amino acids, or amino acids, including non- codeable, have been added to the naturally occurring peptide.
[0107] Examples of insulin analogues are Gly(A21), Arg(B31), Arg(B32) human insulin (insulin glargine); Lys(B3), Glu(B29) human insulin (insulin glulisine); Lys(B28), Pro(B29) human insulin (insulin lispro); Asp(B28) human insulin (insulin aspart); human insulin, wherein proline in position B28 is replaced by Asp, Lys, Leu, Vai or Ala and wherein in position B29 Lys may be replaced by Pro; Ala(B26) human insulin; Des(B28-B30) human insulin; Des(B27) human insulin and Des(B30) human insulin.
[0108] Examples of insulin derivatives are, for example, B29-N-myristoyl-des(B30) human insulin, Lys(B29) (N- tetradecanoyl)-des(B30) human insulin (insulin detemir, Levemir®); B29-N-palmitoyl- des(B30) human insulin; B29-N-myristoyl human insulin; B29-N-palmitoyl human insulin; B28-N- myristoyl LysB28ProB29 human insulin; B28-N-palmitoyl-LysB28ProB29 human insulin; B30-N- myristoyl-ThrB29LysB30 human insulin; B30-N-palmitoyl- ThrB29LysB30 human insulin; B29-N-(N- palmitoyl-gamma-glutamyl)-des(B30) human insulin, B29-N-omega-carboxypentadecanoyl- gamma-L-glutamyl-des(B30) human insulin (insulin degludec, Tresiba®); B29-N-(N-lithocholyl- gamma-glutamyl)-des(B30) human insulin; B29-N-(co-carboxyheptadecanoyl)-des(B30) human insulin and B29-N-(co-carboxyheptadecanoyl) human insulin.
[0109] Examples of GLP-1, GLP-1 analogues and GLP-1 receptor agonists are, for example, Lixisenatide (Lyxumia®), Exenatide (Exendin-4, Byetta®, Bydureon®, a 39 amino acid peptide which is produced by the salivary glands of the Gila monster), Liraglutide (Victoza®), Semaglutide, Taspoglutide, Albiglutide (Syncria®), Dulaglutide (Trulicity®), rExendin-4, CJC-1134-PC, PB-1023, TTP-054, Langlenatide / HM-11260C (Efpeglenatide), HM-15211 , CM-3, GLP-1 Eligen, ORMD- 0901 , NN-9423, NN-9709, NN-9924, NN-9926, NN-9927, Nodexen, Viador-GLP-1, CVX-096, ZYOG-1 , ZYD-1 , GSK-2374697, DA-3091, MAR-701 , MAR709, ZP-2929, ZP-3022, ZP-DI-70, TT- 401 (Pegapamodtide), BHM-034. MOD-6030, CAM-2036, DA-15864, ARI-2651, ARI-2255, Tirzepatide (LY3298176), Bamadutide (SAR425899), Exenatide-XTEN and Glucagon-Xten.
[0110] An example of an oligonucleotide is, for example: mipomersen sodium (Kynamro®), a cholesterol- reducing antisense therapeutic for the treatment of familial hypercholesterolemia or RG012 for the treatment of Alport syndrom. Examples of DPP4 inhibitors are Linagliptin, Vildagliptin, Sitagliptin, Denagliptin, Saxagliptin, Berberine.
[0111] Examples of hormones include hypophysis hormones or hypothalamus hormones or regulatory active peptides and their antagonists, such as Gonadotropine (Follitropin, Lutropin, Choriongonadotropin, Menotropin), Somatropine (Somatropin), Desmopressin, Terlipressin, Gonadorelin, Triptorelin, Leuprorelin, Buserelin, Nafarelin, and Goserelin.
[0112] Examples of polysaccharides include a glucosaminoglycane, a hyaluronic acid, a heparin, a low molecular weight heparin or an ultra-low molecular weight heparin or a derivative thereof, or a sulphated polysaccharide, e.g. a poly-sulphated form of the above-mentioned polysaccharides, and / or a pharmaceutically acceptable salt thereof. An example of a pharmaceutically acceptable salt of a poly-sulphated low molecular weight heparin is enoxaparin sodium. An example of a hyaluronic acid derivative is Hylan G-F 20 (Synvisc®), a sodium hyaluronate.
[0113] The term “antibody”, as used herein, refers to an immunoglobulin molecule or an antigen-binding portion thereof. Examples of antigen-binding portions of immunoglobulin molecules include F(ab) and F(ab')2 fragments, which retain the ability to bind antigen. The antibody can be polyclonal, monoclonal, recombinant, chimeric, de-immunized or humanized, fully human, non-human, (e.g., murine), or single chain antibody. In some embodiments, the antibody has effector function and can fix complement. In some embodiments, the antibody has reduced or no ability to bind an Fc receptor. For example, the antibody can be an isotype or subtype, an antibody fragment or mutant, which does not support binding to an Fc receptor, e.g., it has a mutagenized or deleted Fc receptor binding region. The term antibody also includes an antigen-binding molecule based on tetravalent bispecific tandem immunoglobulins (TBTI) and / or a dual variable region antibody-like binding protein having cross-over binding region orientation (CODV).
[0114] The terms “fragment” or “antibody fragment” refer to a polypeptide derived from an antibody polypeptide molecule (e.g., an antibody heavy and / or light chain polypeptide) that does not comprise a full-length antibody polypeptide, but that still comprises at least a portion of a full-length antibody polypeptide that is capable of binding to an antigen. Antibody fragments can comprise a cleaved portion of a full length antibody polypeptide, although the term is not limited to such cleaved fragments. Antibody fragments that are useful in the present invention include, for example, Fab fragments, F(ab')2 fragments, scFv (single-chain Fv) fragments, linear antibodies, monospecific or multispecific antibody fragments such as bispecific, trispecific, tetraspecific and multispecific antibodies (e.g., diabodies, triabodies, tetrabodies), monovalent or multivalent antibody fragments such as bivalent, trivalent, tetravalent and multivalent antibodies, minibodies, chelating recombinant antibodies, tribodies or bibodies, intrabodies, nanobodies, small modular immunopharmaceuticals (SMIP), binding-domain immunoglobulin fusion proteins, camelized antibodies, and VHH containing antibodies. Additional examples of antigen-binding antibody fragments are known in the art.
[0115] The terms “Complementarity-determining region” or “CDR” refer to short polypeptide sequences within the variable region of both heavy and light chain polypeptides that are primarily responsible for mediating specific antigen recognition. The term “framework region” refers to amino acid sequences within the variable region of both heavy and light chain polypeptides that are not CDR sequences, and are primarily responsible for maintaining correct positioning of the CDR sequences to permit antigen binding. Although the framework regions themselves typically do not directly participate in antigen binding, as is known in the art, certain residues within the framework regions of certain antibodies can directly participate in antigen binding or can affect the ability of one or more amino acids in CDRs to interact with antigen.
[0116] Examples of antibodies are anti PCSK-9 mAb (e.g., Alirocumab), anti IL-6 mAb (e.g., Sarilumab), and anti IL-4 mAb (e.g., Dupilumab).
[0117] Pharmaceutically acceptable salts of any API described herein are also contemplated for use in a drug or medicament in a drug delivery device. Pharmaceutically acceptable salts are for example acid addition salts and basic salts.
[0118] Those of skill in the art will understand that modifications (additions and / or removals) of various components of the APIs, formulations, apparatuses, methods, systems and embodiments described herein may be made without departing from the full scope and spirit of the present invention, which encompass such modifications and any and all equivalents thereof.
[0119] An example drug delivery device may involve a needle-based injection system as described in Table 1 of section 5.2 of ISO 11608-1 :2014(E). As described in ISO 11608-1 :2014(E), needlebased injection systems may be broadly distinguished into multi-dose container systems and single-dose (with partial or full evacuation) container systems. The container may be a replaceable container or an integrated non-replaceable container. As further described in ISO 11608-1 :2014(E), a multi-dose container system may involve a needlebased injection device with a replaceable container. In such a system, each container holds multiple doses, the size of which may be fixed or variable (pre-set by the user). Another multi-dose container system may involve a needle-based injection device with an integrated non-replaceable container. In such a system, each container holds multiple doses, the size of which may be fixed or variable (pre-set by the user).
[0120] As further described in ISO 11608-1 :2014(E), a single-dose container system may involve a needle-based injection device with a replaceable container. In one example for such a system, each container holds a single dose, whereby the entire deliverable volume is expelled (full evacuation). In a further example, each container holds a single dose, whereby a portion of the deliverable volume is expelled (partial evacuation). As also described in ISO 11608-1 :2014(E), a single-dose container system may involve a needle-based injection device with an integrated non- replaceable container. In one example for such a system, each container holds a single dose, whereby the entire deliverable volume is expelled (full evacuation). In a further example, each container holds a single dose, whereby a portion of the deliverable volume is expelled (partial evacuation).
[0121] Brief description of the drawings
[0122] In the following, examples of an electronic device for vein illumination and a method of vein illumination will be described in greater detail by making reference to the drawings, in which:
[0123] Fig. 1 schematically illustrates one example of a mobile electronic device described herein, Fig. 2 shows a schematic side view of the mobile electronic device,
[0124] Fig. 3 shows a schematic illustration of a scenario of using the mobile electronic device for illuminating veins of a human or animal body,
[0125] Fig. 4 shows a further example of the mobile electronic device,
[0126] Fig. 5 is a block diagram showing numerous components of the mobile electronic device,
[0127] Fig. 6 shows a further example of functions of the mobile electronic device,
[0128] Fig. 7 is a schematic representation of a configuration of the mobile electronic device when e.g. switched into a vein illumination mode,
[0129] Fig. 8 shows a holder for the mobile electronic device in an initial configuration, Fig. 9 shows the holder according to Fig. 9 in a deployed configuration,
[0130] Fig. 10 is a flowchart of a method of illuminating veins of a human or animal body by making use of the mobile electronic device, Fig. 11 shows an example of a patient care kit to be used with the mobile electronic device in an initial configuration prior use, and
[0131] Fig. 12 shows the patient care kit with the mobile electronic device for illuminating veins of a human or animal body,
[0132] Fig. 13 shows an example of using the mobile electronic device with the patient care kit to illuminate a region of interest of a human or animal body,
[0133] Fig. 14 shows a configuration of a display of the mobile electronic device in a first step of using the mobile electronic device to illuminate the region of interest of the human or animal body,
[0134] Fig. 15 shows a configuration of a display of the mobile electronic device in a second step of using the mobile electronic device to illuminate the region of interest of the human or animal body, and
[0135] Fig. 16 shows a configuration of a display of the mobile electronic device in a third step of using the mobile electronic device to illuminate the region of interest of the human or animal body.
[0136] Detailed description
[0137] In Figs. 1-7 there are shown numerous examples of a mobile electronic device 10, which is either implemented as a smart phone 50 or as a smartwatch 52. The mobile electronic device 10 comprises a housing 11 with a front side 12 and a backside 14. The backside 14 is located opposite to the front side 12. The front side 12 and the backside 14 are mutually interconnected by a sidewall 13.
[0138] As it is particularly apparent from Figs. 1-7 the front side 12 of the mobile electronic device 10 is provided with a two-dimensional display 30. The display 30 may be implemented as a touch- sensitive display. In this way, the display 30 may even represent a input unit 42 via which numerous user inputs or user commands can be entered into the mobile electronic device 10. The input unit 42 is operably connected to a processor 40 or controller.
[0139] The input unit 42 may be provided at least partially by the display 30. Apart from that the input unit 42 may be provided with numerous actuating elements 15, 16, 17, which may be located, arranged or integrated in the sidewall 13. The actuating elements 15, 16, 17 may be implemented as depressible button. They may slightly protrude from a lateral elongated side of the sidewall 13 of the housing 11. The actuating elements 15, 16, 17 may be depressible by a user to make or to enter a respective user input. In addition, the input unit 42 may comprise a microphone by way of which the input unit 42 may receive speech commands that may be appropriately processed by the processor 40 of the mobile electronic device 10 for processing of user commands.
[0140] The mobile electronic device is further provided with a light source 20, 28. The light source 20, 26 is implemented as a tunable light source 20, 26. The light source 20, 26 is arranged inside or is attached to the housing 11 and is configured to emit illuminating light 21 at a correlated color temperature. The processor 40, which is operatively connected to the tunable light source 20, 26 is configured or operable to adjust the correlated color temperature of the tunable light source 20, 26. Adjusting of the correlated color temperature of the tunable light source 20, 26 means that the processor 40 is configured to adjust or to tune the tunable light source 20, 26 in such a way that the emitted illuminating light 21 features a correspondingly adjusted correlated color temperature.
[0141] Generally, the tunable light source 20, 26 may be adapted to emit illuminating light 21 with at least one variable light characteristics. The variable light characteristics may include at least one of a variable brightness, a variable intensity, a variable correlated color temperature, a variable focal length and / or a variable geometric light propagation characteristics.
[0142] In the example illustration of Figs. 7 the input unit 42 comprises or emulates a display icon 33 and / or a regulator 34 on the display 30. Here, and by depressing the display icon 33, a respective software application may be triggered or started and the mobile electronic device 10 may switch into a vein illumination mode. In the vein illumination mode or before switching into the vein illumination mode the regulator 34, which is a longitudinally or circumferentially movable or rotatable emulated regulator 34, may be moved along the touch sensitive display 30 to individually adjust or to modify the correlated color temperature of the tunable light source.
[0143] While adjusting the color temperature of the tunable light source 20, 26 the display 30 may provide a respective feedback signal. Hence, a portion of the display 30 may shine in the actuality selected correlated color temperature. In some examples, it may be the display 30 that provides the light source 20. Accordingly, and as indicated in Fig. 2 it may be the display 30 that effectively emits the illuminating light 21.
[0144] In some examples, the mobile electronic device 10 may be equipped with the light source 26, which is located on or which is integrated in the backside 14 of the housing 11. Likewise, also the light source 26 is adjustable or tunable with respect to the correlated color temperature of the illuminating light 2T emitted by the tunable light source 26. Also here, adjustment of the correlated color temperature of the emitted illuminating light 2T may be controlled by the processor 40 connected to the tunable light source 26.
[0145] Both light sources 20, 26 may be individually adjusted or controlled by at least one of the regulator 34 or display icon 33 as provided on the touch sensitive display 30 and / or as provided by at least one of the actuating element 15, 16, 17 provided at or in the sidewall 13 of the housing 11.
[0146] The mobile electronic device 10 may be further equipped with an electronic memory 44, which is connected to the processor 40. The processor 40 may be configured to read the data from the memory 44 and to store data in the memory 44. The mobile electronic device 10 is of course provided with an energy source 45, e.g. in form of a rechargeable battery.
[0147] Optionally, the mobile electronic device may be equipped with an orientation sensor 48, which may be operable or configured to determine a momentary orientation of the mobile electronic device with respect to the earth magnetic field. The orientation sensor 48 may be particularly configured to detect a re-orientation and / or to quantitatively measure a rotation or re-orientation of the mobile electronic device.
[0148] In some examples, and when e.g. the display 30 acts as the tunable light source 20 the user may be given the possibility to individually adjust at least one of the correlated color temperature and the intensity of the tunable light source 20. Such a tuning or adjustment may be conducted while the light source 20 is switched off or while the light source shines with a reduced intensity for not blinding the operator or user of the mobile electronic device.
[0149] It may be then that the mobile electronic device 10 is flipped over to illuminate a dedicated portion of the human or animal body for illuminating respective veins at this particular body portion. This re-orientation in the course of flipping over of the mobile electronic device 10 may be registered and / or quantitatively measured by the orientation sensor 48 to switch on the tunable light source and / or to increase the intensity of the emitted illuminating light of the tunable light source.
[0150] A repeated re-orientation and / or a return of the display 30 in the field of view of the user may then be registered or detected again and may be used as a trigger to deactivate the tunable light source 20 and / or to reduce intensity of the tunable light source.
[0151] In other examples, and specifically when the input unit 42 or portions thereof are located outside the light sources 20, 26 a tuning or adjusting of the tunable light sources 20, 26 in terms of at least one of the correlated color temperature and the intensity of the emitted illuminating light may be conducted while the respective tunable light source 20, 26 is and remains unalterably active. This may provide a rather direct feedback to the user when tuning or adjusting the tunable parameters, correlated color temperature and / or intensity of the tunable light source 20, 26.
[0152] According to a further example, the mobile electronic device 10 is further provided with a communication interface 46. The communication interface 46 provide signal transfer or signal transmission between the present mobile electronic device 10 and further external electronic devices. The communication interface 46 may be implemented as a wireless communication interface. It may provide a mobile phone communication link for connecting to a mobile phone network, e.g., implemented as a 2G, 3G, 4G or 5G network.
[0153] The medication interface 46 may further provide signal exchange and communication with RF- based wireless communication networks, such as Wi-Fi, Bluetooth or NFC.
[0154] The mobile electronic device 10 as illustrated in Fig. 4 comprises a smart watch 52. The basic functionality of the smartwatch 52 may be somewhat identical or equivalent to the respective functionality of the smart phone integration or smart phone implementation of the mobile electronic device 10. The smartwatch 52 as shown in Fig. 4 may be fastened to a particular body portion, and hence to a body part 5, specifically to a hand 4 or wrist 3 of a user via a strap 18 or via a respective wrist band.
[0155] In operation the mobile electronic device can be used to emit illuminating light 21 at a rather specific correlated color temperature. The mobile electronic device 10, which is typically implemented as a wearable and / or portable mobile electronic device is typically oriented towards a body part 5 of interest, which is provided with a blood vessel 8 or vein 9 that requires illumination for proper identification.
[0156] A respective skin portion 7 of the body part 5 that comprises such blood vessels 8 or veins 9 can be illuminated by the illuminating light 21. A fraction of the illuminating light 21 is reflected, scattered or deflected and can be then visually detected as reflected light 23 by a respective spatial light detector, such as the human eye 24.
[0157] The input unit 42 of the mobile electronic device 10 allows for a user-individual and rather precise setting or adjusting of the correlated color temperature of the tunable light source 20, 26 in order to provide a maximum or optimal subjective visual perception of the blood vessel 8 or vein 9 on the basis of the reflected light 23. By adapting or modifying the correlated color temperature and / or the intensity of the emitted illuminating light 21, also the reflected light 23 can be optimized to provide a beneficial and optimized subjective visual perception and retrieval of blood vessels 8 of interest and hence of respective veins 9.
[0158] Since the skin 7 of different users or different portions of a body of a user may exhibit different pigmentation it may be beneficial to individually adjust or to modify the correlated color temperature of the emitted illuminating light 21 in order to provide optimum visibility of the blood vessels 8 or veins 9 when illuminated with the emitted illuminating light 21.
[0159] In the example, as indicated in Figs. 2 and 6 the mobile electronic device 10 is further equipped with an ambient light sensor 32. The ambient light sensor 32 may be provided on one of the front side 12 and the backside 14 of the housing 11 of the mobile electronic device 10. By way of the ambient light sensor 32 at least one of an intensity and a spectral composition of ambient light 22 present in the surrounding of the mobile electronic device 10 can be captured and / or analyzed. In some examples, the mobile electronic device 10 may be particularly configured to compensate the influence of varying ambient light conditions. Hence, and depending on at least one of the intensity and a spectral composition of the ambient light 22 captured by the ambient light sensor 32, at least one of the processor 40, the tunable light source 20, 26 may be configured to adjust at least one of the correlated color temperature and / or the intensity of the illuminating light 21 emitted by the tunable light source 20, 26.
[0160] In this way, a superposition of ambient light 22 and illuminating light 21 emitted by the tunable light source 20, 26 can be kept within predefined margins or can be kept at a constant level at the skin 7 of the user even when the ambient light conditions should be subject to modifications or to a change. In this way, the mobile electronic device 10 may provide an automatic adjustment or tuning of at least one of the correlated color temperature and the intensity of the illuminating light 21 emitted by the tunable light source 20, 26 depending on signals and / or depending on an analysis of signals as provided by the ambient light sensor 32 in response to the capturing of ambient light 22.
[0161] As further indicated or illustrated in Figs. 2 and 3, the mobile electronic device 10 comprises at least one camera 36, 38. Here, the camera 36 may be implemented or provided on the front side 12. The camera 38 may be implemented or provided on the backside 14. The mobile electronic device 10 may be provided or equipped with two cameras 36, 38, one of which provided on the front side 12 and the other one of which provided on the backside 38. The function and operability of the ambient light sensor 32 may be provided by or emulated by at least one of the cameras 36, 38. Hence, an image acquired by at least one of the camera 36, 38 may be subject to digital image processing or digital image analysis, e.g. conducted by the processor 40, to derive and / or to measure at least one of an intensity and a spectral composition of ambient light captured by the respective camera 36, 38.
[0162] In the scenario as depicted in Fig. 3 the input unit 42 with its actuating elements 15, 16, 17, which are located at the sidewall 13, provides the particular benefit that while the illuminating light 21 and hence the respective light source 20 is directed towards the skin 7, the actuating element 15, 16, 17 may be actuated by a user of the device 10 to modify or to adjust at least one of the correlated color temperature and the intensity of the illuminating light 21.
[0163] Here and without an intermediate re-orientation of the tunable light source 20, 26 the resulting changes of the reflected light 23 can be directly and rather simultaneously controlled by the human eye 24.
[0164] The electronic memory 44 connected to the processor 40 further provides saving or storing numerous light source settings, which may be selected by a user when making use of the mobile electronic device 10 for illuminating veins 9. The user may be given the possibility to individually adjust and / or to store individually adjusted light source settings and to select such individually configured or individually stored light source settings at a later time when using the mobile electronic device 10 for illuminating veins 9.
[0165] In Fig. 10 numerous steps of illuminating veins of a human or animal body are schematically illustrated in the respective flowchart. Here, in step 100 a mobile electronic device 10 as described herein is used. The mobile electronic device 102 may be arranged in a particular orientation relative to the skin 7 of a patient or user in step 102. Thereafter and in step 104 the mobile electronic device 10 may be switched into a vein illumination mode by way of which illuminating light as emitted by the tunable light source 20, 26 illuminates the skin portion 7 of interest. In a subsequent step 106 the correlated color temperature and / or the intensity of the tunable light source 20, 26 may be adjusted, either automatically, on the basis of signals received from the ambient light sensor 32 or manually, namely, by a user manually operating the input unit 42, e.g. at least one of the actuating elements 15, 16, 17.
[0166] In Figs. 8 and 9 there is shown a particular holder 60, which is suitable to hold the mobile electronic device 10 in a particular orientation or configuration, which is of particular use for illuminating veins 9 of a human or animal body. The holder 60 as shown in Figs. 8 and 9 may be reconfigurable between an initial configuration or storage configuration as shown in Fig. 8 and a deployed configuration or configuration of use as shown in Fig. 9.
[0167] In the present example, the holder 60 comprises a first leg 61 and a second leg 62. The first and the second legs 61, 62 are hinged and hence pivotally attached via a hinge 63. The first and the second legs 61, 62 extend parallel to each other. Both, the first leg 61 and the second leg 62 comprise a bottom side 66, 67 by way of which the holder 60 and hence the first and second legs 61 , 62 can be positioned on an even supporting surface. The bottom sides 66, 67 extend parallel to each other as seen in a plane perpendicular to the axis of rotation as defined by the hinge 63.
[0168] Opposite to the bottom side 66, 67 both legs 61 , 62 comprise a notch 64, 65. The notches 64, 65 are accessible from an upper side of the legs 61 , 62. The notches 64, 65 are somewhat equally sized and / or equally spaced from the hinge 63 as can be seen in the initial configuration of Fig. 8. When in the deployed configuration as shown in Fig. 9 the notches 64, 65 are separated from each other. The radial size of the notches as seen with regard to the axis of rotation of the hinge 63 is designed in accordance to the dimensions and / or geometry of the housing 11 of the mobile electronic device 10.
[0169] In the example, as currently illustrated in connection with Figs. 8, 9 and 11, 12 the housing 11 of the mobile electronic device 10 can be at least partially inserted into the notches 64, 65. The radial dimension of the notches 64, 65 may correspond to a height or thickness of the sidewall 13 of the housing 11 of the mobile electronic device 10, such that the mobile electronic device 10 can be at least partially inserted with an elongated portion of the sidewall 13 into the two notches 64, 65 as provided in the first and the second legs 61, 62.
[0170] As particularly illustrated in Fig. 9 the notches 64, 65 comprise a side edge 68, which is slightly slanted or beveled with regards to a notch bottom 69 and / or with regards to the bottom side 66, 67 of the legs 61, 62. In this way, the housing 11 and hence the entire mobile electronic device can be oriented in a slightly beveled or slanted orientation as indicated in Fig. 12, which slanted or beveled configuration might be beneficial to shine the illuminating light 21 at a predefined angle form above onto an arm support 89 of a patient care kit 80 as shown in Figs. 11 and 12.
[0171] Here, a patient may place his lower arm portion 6 onto the arm support 89 to conduct vein penetration or vein piercing. The holder 60 may be movably or detachably positioned to the patient care kit 80 to hold the mobile electronic device 10 in a slightly elevated position while the light source 20, 26 shines at a predefined angle from above onto the arm support 89 and hence onto the arm 6 when placed on the arm support 89.
[0172] In this way, there can be provided well-defined illumination conditions for illuminating veins 9, that may be located on or in an arm 6 of a patient.
[0173] The patient care kit 80 as shown in Figs. 11 and 12 may be of particular benefit for conducting a self-operated or single-handed vein puncturing. The patient care kit 80 comprises a kit housing 81 with a first housing component 82 and a second housing component 83. The housing components 82, 83 may be hingedly connected via a hinge 90.
[0174] In this way, an inside of the first housing component 82 may be folded onto an inside of the second housing component 83 to form a kind of a closed kit housing 81 that resembles a suitcase with first and second foldable or mutually pivotable housing component 82, 83.
[0175] As particularly shown in Figs. 11 and 12 both housing components 82, 83 are provided with numerous compartments 84, 85 to receive at least one item 86, 87. There may be stowed and fastened numerous items in those compartments 84, 85. Some examples of stowable items 86, 87 include bottles, vials, vial adapters, syringes, needles and the like components required for conducting an intravenous injection or infusion.
[0176] As particularly illustrated in Figs. 11 and 12 there may be provided a holder 92, which may protrude from the inside of the housing components 82, 83 when in an open configuration as shown in Fig. 11, in which open configuration the housing component 82, 83 are typically arranged next to each other with their inside housing components 82, 83 facing upwardly.
[0177] The holder 92 may protrude upwardly from any one of the housing components 82, 83. The mobile electronic device holder 60 may be movably or detachably attached to the holder 92 and may be folded into the configuration of use as shown in Figs. 9 and 11. In the configuration of Fig. 12 the notches 64, 65 of the holder 60 may receive at least a portion of the housing 11 of the mobile electronic device 10, which is consequently kept at a well-defined slanted angle above the arm rest or arm support 89, which is beneficial to illuminate a body portion of interest from slightly above while an arm 6 of a patient is in a rest position on the arm support 89.
[0178] With the camera 36, 38 it may be also possible to capture an image 35 of a region of interest 1 of a body part 5 of a user or patient. Here, and as illustrated in Fig. 13, the light source 26 provided at the backside 14 of the mobile electronic device 10 may be used to illuminate a region of interest 1.
[0179] In response to the illumination or even without illumination, the mobile electronic device 10 may be configured to capture an image 35 of the region of interest 1 and to visualize the captured region of interest 1 on a screen of the display 30, e.g. provided on the front side 12 of the mobile electronic device 10.
[0180] In an initial configuration of a camera 38 and / or before capturing an image 35 the display 30 may provide a target frame 39 on the display screen to indicate to a user to place the region of interest 1 in such a configuration relative to the camera 38 such that the region of interest 1 appears as an image 35 inside the target frame 39 on the display screen as indicated in Figs. 14 and 15.
[0181] The camera 38 and / or the processor 40, which is connected to the camera 38, and which may provide digital image analysis, may be particularly configured to derive at least one surface characterization parameter of the region of interest 1, e.g. of a skin 7 in the region of a structure of interest 2, e.g., representing a blood vessel 8 or vein 9.
[0182] The surface characterization parameter may be indicative of a skin color and / or of a surface texture of the skin surface. Based on the surface characterization parameter, the processor 40 may be configured to tune or to adjust the at least one light characteristics of the illuminating light 21 rather autonomously, such as to improve visibility of the region of interest 1 for a direct visual inspection by a user and / or for the image capturing through the camera 38.
[0183] By tuning the light characteristics, e.g., by tuning or adjusting the correlated color temperature of the tunable light source, e.g., by taking into account at least one of the ambient light and the surface characterization parameter of the skin 7 of a patient, the visibility of the structure of interest 2, such as the visibility of a blood vessel 8 or vein 9 can be improved to thereby facilitate puncturing of a blood vessel 8 or vein 9 with a puncturing device, such as an injection cannula or injection needle.
[0184] Accordingly, and by way of tuning or adjusting the tunable light source with respect to at least one of the light characteristics, e.g., by tuning the correlated color temperature of the light source 26, a particular structure of interest 2, such as a blood vessel 8 or vein 9 may become visible as indicated in the illustration of Fig. 16. Visibility of the structure of interest 2 may be improved for the reflected light 23 which is directly detectable by the human eye 24. The visibility may be also enhanced for the camera-based image acquisition and / or for the image representation on the display 30 as indicated in Fig. 16.
[0185] Hence, the display 30 of the mobile electronic device 10 may further assist a user in finding and / or identifying a blood vessel 8 or vein 9 for puncturing. Moreover, and as also indicated in Figs. 14- 16, there may be provided a mode indicator 37 on the display 30 of the mobile electronic device 10 when the tunable light source 20, 26 is in a tuning mode, e.g., when and as long as a tuning or calibration of the tunable light source may take place. This way, the user of the mobile electronic device 10 is directly provided with a visual feedback that the tunable light source 20, 26 is currently subject to a tuning or calibration procedure. The ongoing turing procedure of the tunable light source 20, 26 may be further indicated by a temporal variation of the visibility of the mode indicator 37. Hence, the mode indicator 37 may be subject to variable intensity, variable color or to a blinking while and / or as long as a tuning or calibration of the light source 20, 26 is in progress.
[0186] Reference Numbers
[0187] 1 region of interest
[0188] 2 structure of interest
[0189] 3 wrist
[0190] 4 hand
[0191] 5 body part
[0192] 6 arm
[0193] 7 skin
[0194] 8 blood vessel
[0195] 9 vein
[0196] 10 electronic device
[0197] 11 housing
[0198] 12 front side
[0199] 13 sidewall
[0200] 14 backside
[0201] 15 actuating element
[0202] 16 actuating element
[0203] 17 actuating element
[0204] 18 strap
[0205] 20 light source
[0206] 21 illuminating light
[0207] 22 ambient light
[0208] 23 reflected light
[0209] 24 human eye
[0210] 26 light source
[0211] 30 display
[0212] 32 light sensor
[0213] 33 display icon
[0214] 34 regulator
[0215] 35 image
[0216] 36 camera
[0217] 37 mode indicator
[0218] 38 camera
[0219] 39 target frame
[0220] 40 processor input unit memory energy source communication interface orientation sensor smart phone smartwatch holder leg leg hinge notch notch bottom side bottom side side edge notch bottom patient care kit kit housing housing component housing component compartment compartment item item arm support hinge holder
Claims
PAT24293-WO-PCTClaims1. A mobile electronic device (10) for illuminating veins (9) of a human or animal body, the mobile electronic device (10) comprising: a housing (11), a tunable light source (20; 26) inside or attached to the housing (11) and configured to emit illuminating light (21) at a correlated color temperature, a processor (40) inside the housing (11) and coupled to the tunable light source (20; 26) to adjust the correlated color temperature of the tunable light source (20; 26).
2. The mobile electronic device (10) according to claim 1 , further comprising an input unit (42) coupled to the processor (40) and configured to control or to trigger the processor (40) to adjust the correlated color temperature of the tunable light source (20; 26).
3. The mobile electronic device (10) according to claim 2, wherein the input unit (42) is user controllable and allows a user to manually adjust the correlated color temperature of the tunable light source (20; 26).
4. The mobile electronic device (10) according to claim 2 or 3, wherein the input unit (42) comprises a first actuating element (16) and a second actuating element (17), wherein the first and the second actuating elements (16, 17) are actuatable by a user to increase and / or to decrease the correlated color temperature of the tunable light source (20, 26).
5. The mobile electronic device (10) according to any one of the preceding claims 2-4, wherein correlated color temperature of the tunable light source (20; 26) is adjustable while the tunable light source emits the illuminating light (21).
6. The mobile electronic device (10) according to any one of the preceding claims, further comprising an electronic memory (44) configured to store numerous light source settings, wherein the numerous light source settings distinguish by at least one of the correlated color temperature of the tunable light source (20; 26) and an intensity of the illuminating light (21) emitted by the tunable light source (20;26).
7. The mobile electronic device (10) according to claims 2 and 6, wherein the processor (40) is configured to select a light source setting from the electronic memory (44) and to control operation of the tunable light source (20; 26) on the basis of the selected light source setting.
8. The mobile electronic device (10) according to any one of the preceding claims 2 and 6 or according to claim 7, wherein the processor (40) is configured: to adjust the correlated color temperature of the tunable light source (20) as defined by an operation of the input unit (42), and to store a current setting of the tunable light source (20) as a light source setting in the electronic memory (44).
9. The mobile electronic device (10) according to any one of the preceding claims, wherein the correlated color temperature of the tunable light source (20; 26) is continuously adjustable.
10. The mobile electronic device (10) according to any one of the preceding claims, wherein the housing (11) comprises a front side (12) and a backside (14) opposite to the front side (12) and wherein the tunable light source (20; 26) is provided on one of the front side (12) and the backside (14).
11. The mobile electronic device (10) according to any one of the preceding claims, wherein the housing (10) comprises a sidewall (13) provided with at least one user actuatable actuating element (15, 16, 17) connected to the processor (40) to adjust at least one of an intensity and the correlated color temperature of the tunable light source (20; 26)12. The mobile electronic device (10) according to any one of the preceding claims, further comprising a two-dimensional touch sensitive display (30) with a two-dimensional array of pixels.
13. The mobile electronic device (10) according to claims 10 and 12, wherein the backside (14) of the housing (11) is provided with the tunable light source (26).
14. The mobile electronic device (10) according to claim 12 or 13, wherein the tunable light source (20; 26) is integrated into the two-dimensional touch sensitive display (30).
15. The mobile electronic device (10) according to any one of the preceding claims further comprising an ambient light sensor (32) coupled to the processor (40) and configured to capture ambient light (22), wherein at least one of the ambient light sensor (32) and the processor (40) isconfigured to measure at least one of an intensity and a spectral composition of ambient light (22) captured by the ambient light sensor (32).
16. The mobile electronic device (10) according to claim 15, wherein the processor (40) is configured to adjust at least one of an intensity of the illuminating light (21) and the correlated color temperature of the illuminating light (21) via the processor (40) on the basis of at least one of an intensity and a spectral composition of the ambient light (22) captured by the ambient light sensor (32).
17. The mobile electronic device (10) according to any one of the preceding claims, wherein the mobile electronic device (10) comprises one of a smartwatch (52), a smart phone (50) and a tablet computer.
18. A method of illuminating veins (9) of a human or animal body, the comprising the steps of: using a mobile electronic device (10) comprising a housing (11), a tunable light source (20;26) inside or attached to the housing (11) and a processor (40) inside the housing 111) coupled to the tunable light source (20; 26), emitting illuminating light (21) by the tunable light source (20; 26) and adjusting the correlated color temperature of the tunable light source (20; 26).
19. A computer program for a mobile electronic device (10) to illuminate veins (9) of a human or animal body, the computer program comprising computer readable instructions, which when executed by a processor (40) of the mobile electronic device (10) cause a tunable light source (20; 26) of the mobile electronic device (10), which is coupled to the processor (40) and / or controlled by the processor (40), to emit illuminating light (21) by a tunable light source (20; 26), and to adjust the correlated color temperature of the tunable light source (20; 26).