Blood glucose monitoring method and related apparatus
Patent Information
- Application Number
- PCT/CN2026/074712
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-02-19
- Filing Date
- 2026-01-23
- Publication Date
- 2026-08-27
Smart Images

Figure CN2026074712_27082026_PF_FP_ABST
Abstract
Description
Blood glucose testing methods and related devices
[0001] This application claims priority to Chinese Patent Application No. 202510186935.1, filed on February 19, 2025, entitled "Method and Related Device for Blood Glucose Detection", the entire contents of which are incorporated herein by reference. Technical Field
[0002] This application relates to the field of blood glucose detection technology, and in particular to a blood glucose detection method and related apparatus. Background Technology
[0003] Blood glucose testing is an important component of diabetes management. Test results help assess the degree of glucose metabolism disorder and develop appropriate dietary plans. Traditional blood glucose testing devices require finger-prick blood sampling. To reduce the discomfort of blood collection for users, continuous glucose monitoring (CGM) devices were developed.
[0004] CGM devices do not require finger-prick blood sampling; instead, they indirectly obtain blood glucose levels by detecting the glucose concentration in interstitial fluid. When a user's blood glucose is relatively stable, such as when fasting, the glucose concentration in the interstitial fluid is close to the blood glucose level, accurately reflecting the user's blood glucose. However, when a user's blood glucose changes rapidly, such as after eating, the change in glucose concentration in the interstitial fluid lags behind the change in blood glucose, resulting in an inaccurate reflection of blood glucose levels and poor detection accuracy. Summary of the Invention
[0005] This application provides a blood glucose detection method and related apparatus, which can improve the accuracy of blood glucose detection.
[0006] In a first aspect, embodiments of this application provide a blood glucose detection method applied to a first device. In this method, the first device can acquire a first glucose concentration in interstitial fluid at a first moment, a second glucose concentration within a first time period, and a third glucose concentration within a second time period. The first time period is the time interval from the second moment to the first moment, where the second moment is earlier than the first moment, and the first time period can be considered as a period preceding the first moment. The second time period is the time interval from the first moment to the third moment, where the third moment is later than the first moment, and the second time period can be considered as a period following the first moment. The first device can output the blood glucose level at the first moment based on the first glucose concentration, the second glucose concentration, and the third glucose concentration.
[0007] In this embodiment, the blood glucose level at the first moment can be obtained based on the glucose concentration of the interstitial fluid at the first moment and the glucose concentration over a period of time before and after the first moment. In this embodiment, because the glucose concentration of the interstitial fluid over a period of time after the first moment is combined, the diffusion time of glucose between the interstitial fluid and blood is increased, making the glucose concentration of the interstitial fluid closer to the blood glucose level, which can improve the accuracy of blood glucose detection.
[0008] In one possible implementation, the duration of the second time period is a preset duration; or, the duration of the second time period is a user-defined duration; or, the duration of the second time period is related to the user's scenario.
[0009] The duration of the second time period determines the duration of the delayed collection of glucose concentration in the interstitial fluid. In some embodiments, the longer the second time period, the closer the glucose concentration in the interstitial fluid is to blood glucose, and the higher the accuracy of blood glucose detection.
[0010] The second time period is a preset duration, which can be pre-set in the first device and used directly to detect blood glucose levels at the first moment. Alternatively, the second time period can be user-defined, allowing users to customize it according to their specific blood glucose monitoring needs, thus improving user experience. Alternatively, the duration of the second time period can be related to the user's context. This context could include scenarios where blood glucose levels fluctuate, such as eating or exercising, as most users are concerned about whether their blood glucose levels are within normal ranges. The user's context could also be a relatively stable blood glucose level scenario, such as fasting or sleeping, allowing users to monitor their blood glucose levels in such situations.
[0011] This implementation method offers multiple ways to set the second time period, which can adapt to user needs and improve user experience.
[0012] In one possible implementation, the user can set a custom second time period on the first device. When the duration of the second time period is the user-defined duration, the first device can display a first interface, which includes at least one output strategy, each output strategy corresponding to a second time period. In this example, in response to the user's selection of an output strategy, the first device can determine the second time period.
[0013] In this implementation, the first device can provide an interface for users to customize a second time period, which allows users to customize the duration of delayed collection of glucose concentration in interstitial fluid, thus adapting to user needs and improving user experience.
[0014] In one possible implementation, when the duration of the second time period is related to the user's scenario, the first device can determine the user's scenario based on the collected scenario-related data; alternatively, the first device can determine the user's scenario based on user input. If the first device determines the user's scenario, it can then determine the second time period accordingly.
[0015] For example, the user's scenario may include, but is not limited to: eating scenario, exercising scenario, fasting scenario, or sleeping scenario.
[0016] For example, the first device may include a scene detection unit, which includes at least one of the following: a positioning unit, a camera, and an inertial measurement unit. The scene-related data is data collected by the scene detection unit. In this example, the first device can determine the scene in which the user is located based on the data collected by the scene detection unit. For example, the inertial measurement unit may be a positioning unit, an accelerometer, a gyroscope, etc.
[0017] For example, user input can be input on the interface of the first device or voice input, etc., and this application does not limit this. Here, we will use user input on the interface of the first device as an example. For instance, the first device can provide a user-operable interface on which the user can input the scene they are in, or the interface can include multiple scenes to be selected, and the user can choose the scene they are in. The user's selection of the scene can also be considered user input. In this example, the first device can determine the scene the user is in based on the user input.
[0018] In this implementation, the user's current scenario is related to the second time period, and the first device can detect the user's current scenario to determine the second time period. This eliminates the need for user-defined settings, simplifies user operations, and the second time period is also adapted to the user's current scenario, thus improving the user experience.
[0019] In one possible implementation, the first device is connected to the second device. The user can set a value output strategy on the second device, or the second device can detect the user's current context and determine the output strategy accordingly. The output strategy is related to a second time period. After determining the output strategy, the second device can send it to the first device so that the first device can detect blood glucose levels based on that strategy. And because the output strategy is related to the second time period, the first device can determine the second time period.
[0020] In this implementation, the first device can receive an output strategy from the second device, which indicates a second time period. The first device can determine the second time period based on the output strategy.
[0021] In this implementation, the user can set the output strategy on the second device, or the second device can detect the user's scene and determine the output strategy accordingly, without needing to configure it on the first device, thus simplifying the setup of the first device.
[0022] When the first device and the second device are connected, after the first device obtains the blood glucose level at a first moment, it can send the blood glucose level at the first moment to the second device, so that the second device can display the blood glucose level at the first moment.
[0023] In this implementation, users frequently use a second device. Users set output strategies on the second device, and the second device displays the blood glucose level at the first moment, which can adapt to users' usage habits and improve user experience.
[0024] In one possible implementation, the output strategy is also used to indicate a first detection time period, where the first moment is included within the first detection time period. In this implementation, for example, when setting the output strategy, the user can also set the first detection time period corresponding to the output strategy, so that the first device can use the output strategy to detect blood glucose within that first detection time period.
[0025] In this implementation, the first detection time period can be a historical time period, a periodic time period, a blood glucose rising phase, or a blood glucose falling phase.
[0026] In this implementation, the user can set the first detection time period corresponding to the output strategy, so that the first device can use the output strategy to detect blood glucose during the first detection time period that the user is interested in. This can not only improve the accuracy of blood glucose detection, but also adapt to user needs.
[0027] In one possible implementation, during periods other than the first detection time, such as the second detection time, the first device can use a real-time output strategy to obtain the user's blood glucose. For example, taking the fourth moment of the second detection time as an example, the first device can obtain the fourth glucose concentration of the interstitial fluid at the fourth moment, and the fifth glucose concentration during the third time period. The third time period is the period from the fifth moment to the fourth moment, the fifth moment is earlier than the fourth moment, the fourth moment is included in the second detection time period, and the second detection time period does not overlap with the first detection time period.
[0028] The first device can output the blood glucose level at the fourth time point based on the fourth and fifth glucose concentrations.
[0029] In one possible implementation, the first device can also provide a comparative detection function. For example, the first device can calculate blood glucose using both a delayed output strategy and a real-time output strategy. In this way, the second device can display the blood glucose results calculated using both the delayed output strategy and the real-time output strategy. Users can compare the blood glucose results of the two output strategies and understand that the delayed output strategy can improve the accuracy of blood glucose detection.
[0030] The delayed output value refers to the glucose concentration of interstitial fluid collected after the first moment, so that the first device can combine the current moment with the glucose concentration of interstitial fluid collected before and after the current moment to obtain the blood glucose at the current moment, thereby improving the accuracy of blood glucose.
[0031] Real-time data output refers to obtaining the blood glucose level at the current moment by using the glucose concentration of interstitial fluid at the current moment and a period of time prior to the current moment (i.e., a historical time period). The first device can combine the glucose concentration of interstitial fluid at the current moment and a period of time prior to the current moment to obtain the blood glucose level at the current moment. In the real-time data output strategy, the first device does not need to delay the collection of interstitial fluid glucose concentration over a period of time after the current moment, so the blood glucose acquisition speed is fast and real-time data output can be achieved.
[0032] In this implementation, the blood glucose obtained using a delayed output strategy can be used as the first blood glucose, and the blood glucose obtained using a real-time output strategy can be used as the second blood glucose. The first device can output the first blood glucose and the second blood glucose, so that the user can compare the blood glucose results of the two output strategies and know that the delayed output strategy can improve the accuracy of blood glucose detection.
[0033] For example, the accuracy of the first blood glucose level is higher than that of the second blood glucose level; the first blood glucose level is within the abnormal range, while the second blood glucose level is not. Thus, based on the first blood glucose level, users can promptly determine if their blood glucose is within the abnormal range and take appropriate measures to ensure their safety.
[0034] In one possible implementation, after the first device acquires the blood glucose level at a first moment, if the blood glucose level at the first moment is within an abnormal range, the first device can output a first prompt message to notify the user that the blood glucose level at the first moment is abnormal.
[0035] In this implementation, when the first device detects an abnormal blood glucose level at the first moment, it can promptly remind the user of the abnormal blood glucose level to ensure the user's safety.
[0036] In one possible implementation, the first device can provide a function to remind the user to start blood glucose testing using an output strategy, thereby improving the user experience. In this implementation, for example, after determining the user's current scenario and the corresponding output strategy, the first device can output a second prompt message to ask the user whether to start blood glucose testing using the output strategy. In response to the user's confirmation to start blood glucose testing, the first device can begin testing blood glucose using the output strategy corresponding to the scenario.
[0037] In one possible implementation, the first device can provide a function to remind the user to start a comparative test. In this implementation, in response to the user's confirmation to start blood glucose testing using a value output strategy, the first device can output a third prompt message to remind the user whether to start the comparative test. In response to the user's confirmation to start the comparative test, the first device can start testing blood glucose, and the first device can use a delayed value output strategy to obtain a first blood glucose level and a real-time value output strategy to obtain a second blood glucose level. Accordingly, the first device can output the first blood glucose level and the second blood glucose level.
[0038] In this implementation, the first device can interact with the user during the blood glucose detection process to remind the user to start the blood glucose detection using the output strategy and to enable the comparison test, which can be adapted to the user's needs and improve the user experience.
[0039] In one possible implementation, the first device can acquire blood glucose levels at each of the second to third time points based on the first glucose concentration, the second glucose concentration, the third glucose concentration, and processing parameters.
[0040] In this implementation, the processing parameters can be pushed from the cloud, and are learned by the cloud based on at least one set of data reported by the first device. Each set of data may include: the first glucose concentration of interstitial fluid at a first moment, the second glucose concentration within a first time period, the third glucose concentration within a second time period, the initial processing parameters, and the blood glucose level at the first moment. It should be understood that the first moment in each set of data may be different.
[0041] In this implementation, multiple sets of data can be uploaded to the cloud. The cloud can then optimize the processing parameters based on the user's multiple sets of data, so that the glucose concentration in the interstitial fluid is closer to that of blood glucose, thereby further improving the accuracy of blood glucose detection.
[0042] In one possible implementation, before acquiring the first glucose concentration of the interstitial fluid at a first moment, the second glucose concentration within a first time period, and the third glucose concentration within a second time period, the first device may collect first physiological data of the interstitial fluid at a first moment, the second physiological data within the first time period, and the third physiological data within the second time period. Specifically, the first device can acquire the first glucose concentration of the interstitial fluid at the first moment based on the first physiological data, acquire the second glucose concentration of the interstitial fluid within the first time period based on the second physiological data, and acquire the third glucose concentration of the interstitial fluid within the second time period based on the third physiological data.
[0043] For example, if the first device is a blood glucose detection device, such as a CGM device, then the first device can collect relevant physiological data for blood glucose detection. In this implementation, the first device can obtain the glucose concentration of interstitial fluid at a first moment and for a period of time before and after the first moment, which can prepare the first device to obtain the blood glucose at the first moment.
[0044] Secondly, embodiments of this application provide a blood glucose detection method applied to a first device. In this method, at a first moment, the first device can receive a blood glucose detection command. This blood glucose detection command can be user-triggered, such as when a user performs an operation to confirm the adoption of an output strategy and begin blood glucose detection, thus triggering the blood glucose detection command. Alternatively, it can be triggered internally by the first device, such as within a fixed time period, where the first device can internally trigger a blood glucose detection command.
[0045] In response to a blood glucose detection command, the first device can acquire the first glucose concentration in the interstitial fluid at a first moment, the second glucose concentration within a first time period, and the third glucose concentration within a second time period. The first time period is the period from the second moment to the first moment, with the second moment being earlier than the first moment. The second time period is the period from the first moment to the third moment, with the third moment being later than the first moment. Based on the first, second, and third glucose concentrations, the first device outputs the blood glucose level at the first moment at a sixth moment, with the sixth moment not earlier than the third moment.
[0046] Furthermore, in response to the blood glucose detection command at the first moment, the third device can output the second blood glucose level at the seventh moment, based on the first glucose concentration and the second glucose concentration. The seventh moment is earlier than the sixth moment. In other words, the third device can adopt a real-time output strategy to output the second blood glucose level at the first moment.
[0047] In this application, the first device can incorporate the glucose concentration of interstitial fluid over a period of time after the current moment, allowing more time for glucose diffusion between the interstitial fluid and blood. This makes the glucose concentration in the interstitial fluid closer to blood glucose levels, thus improving the accuracy of blood glucose detection. In contrast, the third device does not incorporate the glucose concentration of interstitial fluid over a period of time after the current moment. Instead, it determines the blood glucose level at the first moment based on the glucose concentration of interstitial fluid over a period of time before the current moment and the glucose concentration of interstitial fluid at the current moment. Compared to blood glucose obtained using a real-time output strategy, the blood glucose obtained in this application by incorporating the glucose concentration of interstitial fluid over a period of time after the current moment (i.e., using a delayed output strategy) is more accurate.
[0048] The second time period has a preset duration, which can be pre-set in the first device. The first device can directly use this second time period to detect blood glucose at the first moment. Alternatively, the second time period can be a user-defined duration, allowing users to customize the second time period according to their blood glucose monitoring needs, thus adapting to user requirements and improving user experience. Alternatively, the duration of the second time period can be related to the user's context.
[0049] The second time period can be a user-defined duration. For example, in one possible implementation, the first device can display a first interface including at least one selection control. The selection control indicates a value output strategy, and each value output strategy corresponds to a second time period. In response to the user's operation on the selection control, the first device can determine the value output strategy and the second time period corresponding to the value output strategy.
[0050] The duration of the second time period is related to the user's scenario. In one possible implementation, the first device can display a first interface, which includes at least one selection control. The selection control indicates a scenario corresponding to the output strategy, and one output strategy corresponds to one second time period. In this implementation, in response to the user's operation on the selection control, the first device can determine the user's scenario, the output strategy corresponding to the scenario, and the second time period corresponding to the output strategy.
[0051] The duration of the second time period is related to the user's scenario. In one possible implementation, the first device can also provide an interface for the user to input the scenario. In this implementation, the first device can display the interface and, in response to the user's input of the scenario on the interface, determine the output strategy corresponding to the scenario. The output strategy is used to indicate the second time period.
[0052] In one possible implementation, the scenario is any of the following: eating scenario, exercising scenario, fasting scenario, or sleeping scenario.
[0053] In one possible implementation, the blood glucose level at a first moment is called the first blood glucose level, and the method further includes: a first device determining the second blood glucose level at the first moment based on a first glucose concentration and a second glucose concentration.
[0054] Specifically, the first device outputs the blood glucose level at a first moment, including: outputting the first blood glucose level at a sixth moment, and outputting the second blood glucose level at a seventh moment, with the seventh moment being earlier than the sixth moment. Furthermore, the seventh moment is not earlier than the first moment.
[0055] In this implementation, the first device can use both a delayed output strategy and a real-time output strategy to detect blood glucose. Because the real-time output strategy does not require a delay in collecting the glucose concentration of interstitial fluid after the initial time point, the first device can output the second blood glucose level more quickly. Compared to the second blood glucose level, because the first device combines the glucose concentration of interstitial fluid after the initial time point, it allows more time for glucose to diffuse between the interstitial fluid and blood, making the glucose concentration in the interstitial fluid closer to the blood glucose level, thus improving the accuracy of blood glucose detection.
[0056] In one possible implementation, after determining the output strategy corresponding to the scenario, the first device can also output a second prompt message to prompt the user whether to adopt the output strategy to start blood glucose testing. Specifically, in response to the user's confirmation, the first device can adopt the output strategy to test blood glucose.
[0057] In one possible implementation, before using the output strategy to detect blood glucose, a third prompt message can be output to prompt the user whether to start the comparison test. In response to the user's confirmation, the first device determines the second blood glucose level at a first time based on the first glucose concentration and the second glucose concentration. Alternatively, the first device can output the first blood glucose level at a sixth time and the second blood glucose level at a seventh time, with the seventh time being earlier than the sixth time.
[0058] In this implementation, the first device can interact with the user during the blood glucose detection process to remind the user to start the blood glucose detection using the output strategy and to enable the comparison test, which can be adapted to the user's needs and improve the user experience.
[0059] In one possible implementation, when the first device acquires a first blood glucose level and a second blood glucose level, the method further includes: the first device outputting a fourth prompt message, the fourth prompt message indicating that the accuracy of the first blood glucose level is higher than that of the second blood glucose level.
[0060] In this implementation, the first device can use a comparative detection method, employing both delayed output and real-time output strategies to detect blood glucose levels. It can also indicate that the accuracy of the first blood glucose level is higher than that of the second blood glucose level, allowing the user to know that the first blood glucose level obtained using the delayed output strategy is more accurate.
[0061] Thirdly, embodiments of this application provide a blood glucose detection system, which may include a second device and a first device. The first and second devices can be connected, and the first device is used to perform the methods described in the first to second aspects.
[0062] In some embodiments, the first device may be a blood glucose testing device, such as a CGM device, and the second device may be a terminal device, such as a mobile phone, computer, smartwatch, smart bracelet, smart glasses, or smart ring.
[0063] Fourthly, embodiments of this application provide an electronic device that may include a processor and a memory, the memory being used to store code instructions and the processor being used to execute the code instructions to perform the methods described in the first to second aspects.
[0064] Fifthly, embodiments of this application provide a computer-readable storage medium storing a computer program or instructions that, when executed on a computer, cause the computer to perform the methods described in the first to second aspects.
[0065] In a sixth aspect, embodiments of this application provide a computer program product including a computer program, which, when run on a computer, causes the computer to perform the methods described in the first to second aspects.
[0066] In a seventh aspect, this application provides a chip or chip system including at least one processor and a communication interface. The communication interface and the at least one processor are interconnected via a circuit. The at least one processor is used to run computer programs or instructions to perform the methods described in the first to second aspects. The communication interface in the chip can be an input / output interface, pins, or circuits, etc.
[0067] In one possible implementation, the chip or chip system described above in this application further includes at least one memory storing instructions. The memory can be an internal storage unit of the chip, such as a register or cache, or it can be a storage unit of the chip itself (e.g., read-only memory, random access memory, etc.).
[0068] In some embodiments, a blood glucose detection system, an electronic device, a computer-readable storage medium, a computer program product, and a chip or chip system may be referred to as the relevant apparatus provided in the embodiments of this application.
[0069] It should be understood that the second to seventh aspects of this application correspond to the technical solutions of the first aspect of this application, and the beneficial effects achieved by each aspect and the corresponding feasible implementation are similar, and will not be repeated here. Attached Figure Description
[0070] Figure 1A is a schematic diagram of a scenario where a CGM device detects blood glucose.
[0071] Figure 1B is a schematic diagram of a CGM device provided in an embodiment of this application;
[0072] Figure 2 is a schematic diagram showing the relationship between glucose concentration in interstitial fluid and blood glucose levels;
[0073] Figure 3 is a schematic diagram of a blood glucose change curve displayed on a terminal device;
[0074] Figure 4 shows another schematic diagram of the relationship between glucose concentration in interstitial fluid and blood glucose.
[0075] Figure 5 is a schematic diagram of a blood glucose detection method provided in an embodiment of this application;
[0076] Figure 6 is a flowchart illustrating one embodiment of the blood glucose detection method provided in this application.
[0077] Figure 7A is a schematic diagram of a scenario in which the blood glucose detection method provided in the embodiments of this application is applicable;
[0078] Figure 7B is a schematic diagram of a user-set output value strategy provided in an embodiment of this application;
[0079] Figure 8 is a schematic diagram of a blood glucose detection method provided in an embodiment of this application;
[0080] Figure 9A is another schematic diagram of blood glucose detection provided in an embodiment of this application;
[0081] Figure 9B is a schematic diagram of a blood glucose detection process provided in an embodiment of this application;
[0082] Figure 10A is another schematic diagram of blood glucose detection provided in an embodiment of this application;
[0083] Figure 10B is a schematic diagram of another blood glucose detection process provided in an embodiment of this application;
[0084] Figure 10C is a schematic diagram of a terminal device displaying a blood glucose change curve provided in an embodiment of this application;
[0085] Figure 11A is another schematic diagram of blood glucose detection provided in an embodiment of this application;
[0086] Figure 11B is a schematic diagram of another blood glucose detection process provided in an embodiment of this application;
[0087] Figure 12 is another schematic diagram of blood glucose detection provided in an embodiment of this application;
[0088] Figure 13 is another schematic diagram of the blood glucose change curve displayed by the terminal device provided in the embodiment of this application;
[0089] Figure 14 is a schematic diagram of the optimization processing parameters provided in an embodiment of this application. Detailed Implementation
[0090] Blood glucose testing helps assess the degree of glucose metabolism disorder and develop appropriate dietary plans. Traditional blood glucose testing devices use finger-prick blood sampling to measure blood glucose levels. However, blood glucose levels are closely related to a person's diet and lifestyle. For users with abnormal blood glucose levels, frequent blood glucose monitoring is necessary to prevent dangerous incidents. Abnormal blood glucose can be either hyperglycemia or hypoglycemia. Currently, to reduce the discomfort of finger-prick blood sampling, continuous glucose monitoring (CGM) devices have emerged.
[0091] CGM devices do not require finger-prick blood sampling; instead, they obtain blood glucose levels by detecting the glucose concentration in interstitial fluid. Figure 1A is a schematic diagram of a scenario where a CGM device detects blood glucose. Referring to Figure 1A, this scenario may include a CGM device and a terminal device. The CGM device and the terminal device can be connected wirelessly or via a wired connection. Wireless connections may include, but are not limited to, Bluetooth connections, wireless local area network (WLAN) connections, etc.
[0092] In some embodiments, the terminal device may be referred to as user equipment (UE), terminal, etc. For example, the terminal device may be a mobile phone, tablet, personal digital assistant (PDA), handheld device with wireless communication function, computing device, in-vehicle device or wearable device, virtual reality (VR) terminal device, augmented reality (AR) terminal device, wireless terminal in industrial control, wireless terminal in smart home, etc. The form of the terminal device is not specifically limited in the embodiments of this application.
[0093] It should be understood that Figure 1A uses a mobile phone as an example of the terminal device for illustration.
[0094] Users can wear a CGM (Continuous Glucose Monitoring) device to monitor their blood glucose levels. In this scenario, the user can operate a terminal device to trigger a monitoring command sent to the CGM device, instructing the CGM device to provide the user's blood glucose level. In response to the monitoring command, the CGM device monitors the user's blood glucose level and sends it back to the terminal device. Based on the received blood glucose data from the CGM device, the terminal device can display the user's blood glucose level on the user interface (UI), such as showing the specific numerical value. It's understandable that because the CGM device can continuously collect the user's blood glucose levels, it can continuously provide the terminal device with data at different times. Correspondingly, the terminal device can display a blood glucose level curve on the UI based on the user's blood glucose levels at different times.
[0095] The following section, using the CGM device structure shown in Figures 1A and 1B as examples, explains the principle of CGM device for blood glucose detection:
[0096] In some embodiments, referring to FIG1A, the CGM device may include: a processor 11, a sensor 12, a receiver 13, and a transmitter 14.
[0097] When a user wears the CGM device, sensor 12 can be inserted subcutaneously. Sensor 12 is used to collect the user's physiological data.
[0098] The processor 11 is used to obtain the glucose concentration of the user's interstitial fluid (IF) based on the physiological data collected by the sensor 12. The glucose concentration of the IF can be expressed as IG (interstitial fluid glucose).
[0099] In some embodiments, the processor 11 may store a conversion relationship between IG and blood glucose (BG). The processor 11 can convert IG to BG according to this conversion relationship. Exemplarily, the conversion relationship may be expressed as a formula, a correction algorithm, or a model, etc., and the embodiments of this application are not limited thereto.
[0100] In some embodiments, the processor 11 may include one or more processing units. These different processing units may be independent devices or integrated within one or more processors.
[0101] In some embodiments, the processor 11 may also include a memory for storing instructions and data. The processor 11 can execute the instructions stored in the memory to perform blood glucose detection.
[0102] Receiver 13 and transmitter 14 are used to enable communication between the CGM device and other terminal devices. In some embodiments, receiver 13 is used to receive information from the terminal device, and transmitter 14 is used to send information to the terminal device. The information may include, but is not limited to, instructions, data, etc. For example, the instruction may be a detection instruction, and the data may be the user's blood glucose level.
[0103] In some embodiments, the receiver 13 and the transmitter 14 can be integrated into a single unit, for example, it can be embodied in a communication chip. The communication chip can be, for example, a Bluetooth communication chip or a WLAN communication chip, which can integrate the function of the receiver 13 receiving information and the function of the transmitter 14 sending information.
[0104] Figure 1B is a schematic diagram of a CGM device provided in an embodiment of this application. Referring to Figure 1B, the processor 11 may include a filtering / calibration current module and a data processing module, and the sensor 12 may include a current sensor and a temperature sensor.
[0105] A temperature sensor is used to collect the user's skin temperature.
[0106] In some embodiments, sensor 12 may include a platinum electrode. When sensor 12 is inserted subcutaneously into the user, the platinum electrode can catalyze the oxidation of glucose in the interstitial fluid, generating an electrical signal.
[0107] A current sensor is used to collect electrical signals to obtain current. The current collected by the current sensor is directly proportional to the glucose concentration in the interstitial fluid.
[0108] In some embodiments, the data processing module is configured to calculate the glucose concentration of interstitial fluid based on the current collected by the current sensor, and convert the glucose concentration of interstitial fluid into blood glucose according to a conversion relationship.
[0109] In practical applications, the current collected by the current sensor is mostly the current generated by glucose catalysis in the interstitial fluid. However, the conductivity of the interstitial fluid changes with the user's skin temperature, affecting the propagation of current within the interstitial fluid and thus the accuracy of the current collected by the current sensor. Directly using the current collected by the current sensor as the current generated by glucose catalysis in the interstitial fluid would affect the accuracy of the glucose concentration in the interstitial fluid. To improve the accuracy of glucose concentration in the interstitial fluid and the accuracy of blood glucose detection, in some embodiments, skin temperature can be used to compensate (or process) the current collected by the current sensor to obtain the current generated by glucose catalysis in the interstitial fluid, thereby improving the accuracy of the current and more accurately reflecting blood glucose levels.
[0110] In this embodiment, the filtering / calibrating current module is used to compensate the current collected by the current sensor according to the user's skin temperature to obtain a compensated current, which can be used as the current generated by glucose catalysis in the interstitial fluid.
[0111] Correspondingly, the data processing module is used to calculate the glucose concentration of the interstitial fluid based on the current generated by glucose catalysis in the interstitial fluid, and to convert the glucose concentration of the interstitial fluid into blood glucose according to the conversion relationship.
[0112] The principle behind the CGM device's conversion of interstitial fluid glucose concentration into blood glucose, as illustrated in Figure 2, is explained below:
[0113] In some embodiments, a two-compartment model can be used to describe the relationship between glucose concentration in the interstitial fluid and blood glucose levels. Referring to Figure 2, the interstitial fluid and blood vessels can each be considered as a "compartment." For example, the blood vessel can be compartment 1 with a volume of V1, and the interstitial fluid can be compartment 2 with a volume of V2. Glucose in the blood vessel diffuses through the vessel wall into the interstitial fluid, and glucose in the interstitial fluid also diffuses into the blood vessel. Tissues (such as fat cells and muscle cells) consume glucose in the interstitial fluid. Furthermore, when blood glucose levels rise, the pancreas secretes insulin into the blood vessels, promoting glucose consumption in the tissues and thus lowering blood glucose. Figure 2 also illustrates the diffusion of insulin in blood vessels and interstitial fluid.
[0114] Assuming the diffusion rate of glucose from blood vessels to interstitial fluid is k21, the diffusion rate of glucose from interstitial fluid to blood vessels is k12, and the rate at which tissues consume glucose from interstitial fluid is k02, the following formula 1 can be obtained based on the material balance equation for glucose in interstitial fluid:
[0115] Wherein, C2(t) represents the glucose concentration in the interstitial fluid, and C1(t) represents blood glucose. kij represents the rate of substance transfer from chamber j to chamber i, and in this embodiment, the substance can be glucose. For example, k21 represents the diffusion rate of glucose from chamber 1 (blood vessel) to chamber 2 (interstitial fluid), and k12 represents the diffusion rate of glucose from chamber 2 (interstitial fluid) to chamber 1 (blood vessel).
[0116] Formula 1 can be simplified to Formula 2 after differentiation:
[0117] Where, g = (k 21 V1 / V2)τ,τ=1 / (k 02 +k 12 ).
[0118] Referring to the two-compartment model, Equation 2 can be transformed into the following Equation 3: IG = G(g,τ) * BG Equation 3
[0119] Where IG represents the current blood glucose level C1(t), and BG represents the interstitial fluid glucose concentration C2(t) over a period of time, which can include the current moment. G(g,τ) can be viewed as a conversion relationship or as a processing parameter. In other words, the CGM device can calculate the current blood glucose level based on the interstitial fluid glucose concentration over a period of time using Formula 3 above.
[0120] In some embodiments, G(g,τ) can be preset in the CGM device. G(g,τ) can be obtained through simulation or testing. For example, taking G(g,τ) obtained through testing, during the test, the CGM device can acquire the glucose concentration of interstitial fluid at multiple time points. At time t1, the CGM device can obtain the initial blood glucose based on the glucose concentration of interstitial fluid at time t1, the time interval L1 before time t1, and the initial processing parameters. Alternatively, at time t1, a gold-labeled blood glucose level can be obtained using finger-prick blood sampling; this gold-labeled blood glucose level can be considered an accurate blood glucose level. In this embodiment, the initial blood glucose at time t1 and the gold-labeled blood glucose can be correlated to obtain a set of data. This set of data includes: the glucose concentration of interstitial fluid over a period of time (including time t1 and the time interval L1), the initial processing parameters, the initial blood glucose, and the gold-labeled blood glucose. Repeating this process multiple times can obtain multiple sets of data.
[0121] Based on multiple sets of data, the initial parameters can be continuously optimized so that the initial blood glucose in each set gradually approaches the gold standard blood glucose. When the difference between the initial blood glucose and the gold standard blood glucose is less than or equal to a threshold, the optimized initial parameters can be used as the final processing parameters G(g,τ). In the embodiments of this application, the CGM device can obtain blood glucose based on the glucose concentration of the interstitial fluid and the processing parameter G(g,τ).
[0122] Based on the current method of blood glucose detection using CGM devices, the CGM device can obtain the current blood glucose level based on the glucose concentration of interstitial fluid over a historical time period and the glucose concentration of interstitial fluid at the current moment. Figure 3 is a schematic diagram of a blood glucose change curve displayed on a terminal device. Referring to Figure 3, taking the current time as 8:30 and the historical time period as 34 minutes as an example, the CGM device can obtain the blood glucose level at 8:30 based on the glucose concentration of interstitial fluid in the 34 minutes before 8:30 (e.g., 7:55-8:29) and the glucose concentration of interstitial fluid at 8:30. For example, the CGM device can obtain the glucose concentration of interstitial fluid every 1 minute. The CGM device can obtain the glucose concentration of interstitial fluid at 7:55, 7:56, 7:57, ..., 8:30. The CGM device can obtain the blood glucose level at 8:30 based on the glucose concentration of interstitial fluid in the interstitial fluid over this 35-minute period and the processing parameters.
[0123] For example, referring to Figure 3, the terminal device displays a blood glucose level of 6.3 mmol / L at 8:30, which is within the target range. The target range can be understood as the normal blood glucose range. Based on this calculation method, the CGM device can acquire blood glucose levels per minute, and correspondingly, the terminal device can display a blood glucose change curve based on the blood glucose levels per minute, as shown in the curve in Figure 3.
[0124] Referring to Figure 4, when a user's blood glucose is relatively stable, such as when the user is fasting, the glucose concentration in the interstitial fluid is close to the blood glucose level. Therefore, the glucose concentration in the interstitial fluid accurately reflects the user's blood glucose, and the CGM device can obtain accurate blood glucose readings. However, when a user's blood glucose changes rapidly, such as when the user eats, blood glucose rises quickly. Since it takes time for glucose to diffuse into the interstitial fluid, the change in glucose concentration in the interstitial fluid lags behind the change in blood glucose. In other words, the glucose concentration in the interstitial fluid cannot accurately reflect the user's blood glucose, and the CGM device obtains low-accuracy blood glucose readings.
[0125] Because when blood glucose levels change rapidly—for example, when blood glucose rises, it takes time for glucose to diffuse into the interstitial fluid—or when blood glucose falls, it takes time for glucose in the interstitial fluid to diffuse into the blood—the change in glucose concentration in the interstitial fluid lags behind the change in blood glucose. To make the change in glucose concentration in the interstitial fluid more closely reflect the change in blood glucose, this application allows for a delayed collection of interstitial fluid glucose concentration data based on historical data over a specific period. During this delayed collection period, glucose diffuses, and the glucose concentration in the interstitial fluid can approach the blood glucose level. This allows the interstitial fluid glucose concentration to accurately reflect blood glucose levels, thus improving the accuracy of blood glucose detection using the CGM device.
[0126] Figure 5 is a schematic diagram of a blood glucose detection method provided in an embodiment of this application. Referring to Figure 5, taking the current time as T1 as an example, the historical time period is the time period from time T2 to time T1, and the delayed collection time period is the time period from time T1 to time T3. The glucose concentration of interstitial fluid during the historical time period can be referred to as the historical glucose concentration of interstitial fluid, which can include the glucose concentration of interstitial fluid at each time from time T2 to time T1. In some embodiments, the historical time period can be considered as a period prior to the current time. The glucose concentration of interstitial fluid at the current time can be understood as the glucose concentration of interstitial fluid at time T1. In some embodiments, the delayed collection time period can be considered as a period after the current time, and the glucose concentration of interstitial fluid during this period can include the glucose concentration of interstitial fluid at each time from time T1 to time T3. In some embodiments, the delayed collection time period can also be referred to as the glucose concentration of interstitial fluid in a future time period, which can be referred to as the future glucose concentration of interstitial fluid. It should be understood that in the example of Figure 5, the historical glucose concentration of the interstitial fluid does not include the glucose concentration of the interstitial fluid at time T1, and the future glucose concentration of the interstitial fluid does not include the glucose concentration of the interstitial fluid at time T1.
[0127] In existing technologies, CGM devices can obtain the blood glucose level at the current time (T1) based on the historical glucose concentration of the interstitial fluid and the glucose concentration of the interstitial fluid at the current time (T1). In this embodiment, to improve the accuracy of blood glucose detection, the blood glucose level at the current time (T1) can be obtained based on the glucose concentration of the interstitial fluid at the current time (T1) and the glucose concentration over a period before and after the current time. In this embodiment, because the glucose concentration of the interstitial fluid over a period after the current time is incorporated, the diffusion time of glucose between the interstitial fluid and blood is increased, making the glucose concentration of the interstitial fluid closer to the blood glucose level, thus improving the accuracy of blood glucose detection.
[0128] The blood glucose detection method provided in this application will be described below with reference to specific embodiments. These embodiments can be combined with each other, and the same or similar concepts or processes may not be described again in some embodiments.
[0129] Figure 6 is a schematic flowchart of one embodiment of the blood glucose detection method provided in this application. Referring to Figure 6, the blood glucose detection method provided in this application may include:
[0130] S601, obtain the first glucose concentration of interstitial fluid at the first moment, the second glucose concentration during the first time period, and the third glucose concentration during the second time period. The first time period is the time period from the second moment to the first moment, the second moment is earlier than the first moment, the second time period is the time period from the first moment to the third moment, and the third moment is later than the first moment.
[0131] In this embodiment, the first moment can be considered the current moment. The first time period is the period from the second moment to the first moment, where the second moment is earlier than the first moment, and the first time period can be considered a period of time before the current moment. The second time period is the period from the first moment to the third moment, where the third moment is later than the first moment, and the second time period can be considered a period of time after the current moment.
[0132] The second glucose concentration within the first time period may include the glucose concentration at each moment within the first time period. The first time period may include at least one moment, meaning the second glucose concentration may include the glucose concentration at at least one moment. The third glucose concentration within the second time period may include the glucose concentration at each moment within the second time period. The second time period may include at least one moment, meaning the third glucose concentration may include the glucose concentration at at least one moment.
[0133] In this embodiment, the first time period does not include the first moment, and the second time period also does not include the first moment. Accordingly, the second glucose concentration within the first time period does not include the first glucose concentration, and the third glucose concentration within the second time period does not include the first glucose concentration.
[0134] In some embodiments, the first time period may include a second time period.
[0135] In some embodiments, the second time period may include a third moment.
[0136] In some embodiments, the duration of the first time period and the duration of the second time period may be equal or unequal. For example, if the durations of the first and second time periods are unequal, such as the current time being 8:30, the first time period lasting 30 minutes and the second time period lasting 3 minutes, with a 1-minute interval between adjacent times, the first time period could be 8:00-8:29, and the second time period could be 8:31-8:33. The first time period could include 30 times, and the second time period could include 3 times. The second glucose concentration could include the glucose concentrations of the 30 times, and the third glucose concentration could include the glucose concentrations of the 3 times. In other words, in this example, the blood glucose level at 8:30 can be obtained based on the glucose concentrations of the interstitial fluid at these 30 + 1 + 3 = 34 times.
[0137] The method for obtaining glucose concentration in interstitial fluid in the embodiments of this application is described below:
[0138] Firstly:
[0139] In some embodiments, the entity executing the blood glucose detection method shown in FIG6 can be a CGM device. In this example, the CGM device can collect first physiological data of interstitial fluid at a first moment, second physiological data within a first time period, and third physiological data within a second time period. The first time period and the second time period can be referred to the relevant descriptions above.
[0140] The first time period may include at least one moment, and the second physiological data within the first time period may include physiological data from at least one moment. The second time period may include at least one moment, and the third physiological data within the second time period may include physiological data from at least one moment.
[0141] This section uses the first physiological data of the interstitial fluid at the first moment as an example to introduce the physiological data collected by the CGM device at each moment. In some embodiments, the first physiological data may include skin temperature and current. The skin temperature can be collected by a temperature sensor in the CGM device, and the current can be collected by a current sensor in the CGM device.
[0142] In some embodiments, taking a 1-minute interval between two adjacent time points as an example, the first physiological data may include skin temperature and current within 1 minute. This application does not limit the acquisition frequency of the CGM device within this 1-minute interval. For example, the skin temperature acquisition frequency is 1 time / min, the current acquisition frequency is 1 time / min, and correspondingly, the first physiological data may include one skin temperature and one current.
[0143] In some embodiments, to improve the accuracy of physiological data, the acquisition frequency can be increased. For example, the skin temperature acquisition frequency can be 1 time / min, and the current acquisition frequency can be 30 times / min. Accordingly, the first physiological data may include one skin temperature and 30 currents. In this example, because there are multiple currents, the CGM device can use the average of the 30 currents as the current for 1 minute.
[0144] As described in the above embodiments, since skin surface temperature affects the conductivity of interstitial fluid, and thus affects the current generated by glucose catalysis in the interstitial fluid, as well as the accuracy of the glucose concentration in the interstitial fluid, in some embodiments, the CGM device can use skin surface temperature to compensate for the current, and use the compensated current as the current generated by glucose catalysis in the interstitial fluid. The CGM device can calculate the glucose concentration in the interstitial fluid based on the current generated by glucose catalysis in the interstitial fluid, thereby improving the accuracy of the glucose concentration in the interstitial fluid and the accuracy of blood glucose levels. It should be understood that using skin surface temperature to compensate for the current in the CGM device can be an optional method. The following embodiments use "using skin surface temperature to compensate for the current in the CGM device" as an example for illustration.
[0145] Taking the first physiological data as an example, in some embodiments, the CGM device can pre-store a current compensation algorithm, which can exist in the form of formulas, models, etc. The CGM device can use the current compensation algorithm to compensate the current collected by the CGM device using skin surface temperature to obtain the current generated by glucose catalysis in the interstitial fluid. The current compensation algorithm can be obtained in advance through simulation or testing, and pre-installed in the CGM device; this will not be elaborated further in the embodiments of this application.
[0146] After the CGM device acquires the glucose-catalyzed current in the interstitial fluid, the glucose concentration of the interstitial fluid can be obtained using the following formula 4 based on this glucose-catalyzed current: IG = K × I + B Formula 4
[0147] Where IG represents the glucose concentration in the interstitial fluid, I represents the current generated by glucose catalysis in the interstitial fluid, and K and B are constants and are known quantities.
[0148] As shown in Formula 4 above, the current generated by glucose catalysis in the interstitial fluid is directly proportional to the glucose concentration in the interstitial fluid.
[0149] Taking the first physiological data as an example, the CGM device can obtain the first glucose concentration of the interstitial fluid at the first moment based on the first physiological data.
[0150] Similarly, the second physiological data includes skin surface temperature and current at at least one moment, and the third physiological data includes skin surface temperature and current at at least one moment. The CGM device can obtain the glucose concentration of the interstitial fluid at each moment within the first time period based on the skin surface temperature and current at each moment within the first time period, i.e., the second glucose concentration within the first time period. The CGM device can obtain the glucose concentration at each moment within the second time period based on the skin surface temperature and current of the interstitial fluid at each moment within the second time period, i.e., the third glucose concentration within the second time period.
[0151] Secondly:
[0152] In some embodiments, when a wireless connection is established between the CGM device and the terminal device, the entity executing the blood glucose detection method shown in FIG6 can be the terminal device. In some embodiments, the CGM device can be referred to as the first device, and the terminal device can be referred to as the second device.
[0153] In this example, referring to the description in "One of them," the CGM device can acquire a first glucose concentration of the interstitial fluid at a first moment, a second glucose concentration within a first time period, and a third glucose concentration within a second time period. The CGM device can send the first glucose concentration of the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the third glucose concentration within the second time period to a terminal device, so that the terminal device can acquire the first glucose concentration of the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the third glucose concentration within the second time period.
[0154] S602 outputs the blood glucose level at the first moment based on the first glucose concentration, the second glucose concentration, and the third glucose concentration.
[0155] Firstly:
[0156] When the CGM device is the main instrument for blood glucose detection, the CGM device can use the first glucose concentration, the second glucose concentration, and the third glucose concentration as IG according to Formula 3, and calculate the blood glucose at the first moment using processing parameters.
[0157] For example, taking 8:30 as the first time point, the first glucose concentration is the glucose concentration of the interstitial fluid at 8:30, the second glucose concentration may include the glucose concentration of the interstitial fluid at 30 time points, and the third glucose concentration may include the glucose concentration of the interstitial fluid at 3 time points. In this example, the CGM device can acquire the glucose concentration of the interstitial fluid at a total of 34 time points, which can be represented as IG(34).
[0158] Where IG(34) = IG(1, 2, 3, ..., 34), each number in IG(34) represents the glucose concentration of the interstitial fluid at a given time. For example, 1 can represent the glucose concentration of the interstitial fluid at 8:00, 2 can represent the glucose concentration of the interstitial fluid at 8:01, ..., and so on, 34 can represent the glucose concentration of the interstitial fluid at 8:33. The CGM device can obtain the following formula 4 based on formula 3:
[0159] Here, Gi represents the processing parameters at each time point. For example, G1 represents the processing parameters at 8:00, G2 represents the processing parameters at 8:01, and so on. The processing parameters at each time point can be the same.
[0160] BG(1,2,…,34) represents the intermediate BG value obtained by the CGM device based on the glucose concentration of interstitial fluid at 34 time points and processing parameters. This intermediate BG value can be used to obtain the blood glucose at the first time point, i.e., the blood glucose at 8:30. The intermediate BG value can include all 34 values, because the first time point 8:30 is the 31st of the 34 time points. The CGM device can use the 31st value (e.g., BG31) as the blood glucose at the first time point.
[0161] After obtaining the blood glucose level at the first moment, the CGM device can output the blood glucose level at the first moment.
[0162] In some embodiments, the CGM device may be equipped with a display screen, on which the CGM device can display the blood glucose level at the first moment. The display method of the CGM device can refer to the method of displaying blood glucose on a mobile phone as shown in Figure 3. In some embodiments, the CGM device may also use voice interaction to announce the blood glucose level at the first moment. This application embodiment does not limit the method in which the CGM device outputs the blood glucose level at the first moment, as long as it can be perceived by the user in a timely manner.
[0163] In some embodiments, after the CGM device establishes a wireless connection with the terminal device, the CGM device can send the blood glucose level at the first moment to the terminal device. In this example, in response to the blood glucose level at the first moment, the terminal device can display the blood glucose level at the first moment. As shown in Figure 3, taking a mobile phone as an example, the mobile phone can display the specific value of the blood glucose level.
[0164] Secondly:
[0165] In some embodiments, when the executing entity of the blood glucose detection method is a terminal device connected to the CGM device, the terminal device can output the blood glucose at a first moment based on the first glucose concentration, the second glucose concentration, and the third glucose concentration. The specific calculation method can refer to the description of the CGM device calculating and outputting the blood glucose at the first moment in "one of them".
[0166] In this embodiment, the blood glucose level at the current moment can be obtained based on the glucose concentration of the interstitial fluid at the current moment and the glucose concentration over a period of time before and after the current moment. In this embodiment, because the glucose concentration of the interstitial fluid over a period of time after the current moment is combined, the diffusion time of glucose between the interstitial fluid and the blood is increased. Therefore, when blood glucose changes drastically, the glucose concentration of the interstitial fluid is closer to that of blood glucose, which can improve the accuracy of blood glucose detection.
[0167] As in the above embodiment, the blood glucose level at the current moment can be obtained by combining the glucose concentration of interstitial fluid over a period of time after the current moment (such as the third glucose concentration within the second time period). In some embodiments, the duration of the second time period can be a preset duration.
[0168] For example, the duration of the second time period can be 3 minutes, 5 minutes, or 7 minutes, etc. In this example, the duration of the second time period can be preset in the CGM device. Analysis shows that the glucose concentration in the interstitial fluid lags behind blood glucose by approximately 4-10 minutes. In some embodiments, the duration of the second time period can be set to any value between 4 and 10 minutes.
[0169] In some embodiments, the longer the second time period, the longer glucose diffuses in blood vessels and interstitial fluid, and the closer the glucose concentration in the interstitial fluid is to blood glucose, thus resulting in higher accuracy of blood glucose detection.
[0170] In some embodiments, the duration of the second time period can be a user-defined duration. In this example, the user can set a second time period, and correspondingly, in response to the user's operation of setting the second time period, the CGM device can determine the second time period. In some embodiments, the user can set the second time period on the CGM device, or the user can set the second time period on a terminal device bound to the CGM device, and the terminal device can synchronize the second time period to the CGM device. In both methods, the CGM device can determine the second time period.
[0171] In this example, taking the user setting a second time period on the CGM device as an example, the CGM device can provide a setting interface. For instance, the CGM device can provide a setting interface that includes options for setting the second time period. When the user operates on these options, the CGM device can display a first interface. The user can then set the second time period on this first interface.
[0172] In some embodiments, the first interface may include at least one output strategy, each output strategy corresponding to a second time period. The second time periods corresponding to each output strategy may be different. In this example, the user can select an output strategy, and correspondingly, in response to the user's selection of an output strategy, the CGM device can determine the second time period.
[0173] In some embodiments, the output strategy is used to indicate a delay in collecting the glucose concentration of interstitial fluid for a certain period of time, which is called a second time period. For example, the first interface may display output strategy 1, output strategy 2, and output strategy 3, etc., where the second time period corresponding to output strategy 1 is 3 minutes, the second time period corresponding to output strategy 2 is 5 minutes, and the time period corresponding to output strategy 3 is 7 minutes. For instance, if the user selects output strategy 1, the CGM device can determine that the second time period is 3 minutes.
[0174] In some embodiments, the second time period corresponding to the output strategy can also be 0 min. In this example, the CGM device can determine that the second time period is 0 min, that is, the CGM device can obtain the blood glucose at the first time based on the glucose concentration of the interstitial fluid at the first time and the second glucose concentration within the first time period. In this example, the CGM device does not delay the collection of the glucose concentration of the interstitial fluid within the second time period.
[0175] It should be understood that the embodiments of this application do not show the first interface of the CGM device and the schematic diagram of the user selecting the output value strategy, but can refer to the description in FIG7B.
[0176] In some embodiments, the duration of the second time period is related to the user's scenario. In this example, each scenario may correspond to a second time period. The second time periods for different scenarios may be the same or different. The CGM device can determine the second time period based on the user's scenario.
[0177] The user's scenario can be one where their blood glucose levels fluctuate. For example, the scenario could include, but is not limited to, dining or exercise. During dining, the user's blood glucose level will rise, while during exercise, it will decrease. For instance, in a dining scenario where blood glucose rises, it can diffuse into the interstitial fluid. To ensure the glucose concentration in the interstitial fluid is close to the blood glucose level, the second time period could be 3 minutes.
[0178] In some embodiments, different scenarios can be further subdivided. For example, in a dining scenario, the dining scenario can include a fast-carb scenario and a slow-carb scenario. In a fast-carb scenario, the user's blood glucose rises faster than in a slow-carb scenario. For instance, because the user's blood glucose rises faster in a fast-carb scenario, the glucose diffuses into the interstitial fluid more quickly, and the glucose concentration in the interstitial fluid can approach blood glucose levels within a shorter second time period. Therefore, a second time period, such as 3 minutes, can be set for a fast-carb scenario. Conversely, in a slow-carb scenario, the user's blood glucose rises slower, and the glucose diffuses into the interstitial fluid more slowly. To ensure that the glucose concentration in the interstitial fluid approaches blood glucose levels, a longer second time period, such as 10 minutes, can be set for a slow-carb scenario. Similarly, for example, in an exercise scenario, the exercise scenario can include a jogging scenario and a walking scenario. Compared to the walking scenario, the user's blood sugar decreases faster in the jogging scenario, and glucose in the interstitial fluid diffuses into the blood vessels more quickly. Within a shorter second time period, the glucose concentration in the interstitial fluid can approach blood sugar levels. For example, a second time period of 3 minutes can be set for the jogging scenario. In contrast, the user's blood sugar decreases slower in the walking scenario, and glucose in the interstitial fluid diffuses into the blood vessels more slowly. To make the glucose concentration in the interstitial fluid approach blood sugar levels, a longer second time period, such as 7 minutes, can be set for the walking scenario.
[0179] The user's scenario can also be a scenario where the user's blood glucose is relatively stable. For example, the user's scenario may include, but is not limited to, a fasting scenario and a sleeping scenario. In some embodiments, whether the user is in a sleeping scenario can be determined based on sleep pressure. In a scenario where the user's blood glucose is relatively stable, the glucose concentration in the user's interstitial fluid is close to blood glucose; therefore, the second time period corresponding to a fasting scenario, a sleeping scenario, etc., can be 0 minutes or 1 minute. In this example, because the user's blood glucose is relatively stable and the glucose concentration in the user's interstitial fluid is close to blood glucose, there is no need for or a short delay in collecting the glucose concentration in the user's interstitial fluid, allowing for accurate acquisition of the user's blood glucose. The blood glucose value is displayed quickly, achieving the purpose of real-time blood glucose detection.
[0180] In some embodiments, the CGM device can determine the user's current scene based on user input. For example, user input can be input on the interface of the first device, or voice input, etc., and this application embodiment does not limit this. Here, we will illustrate the example of user input being input on the interface of the first device. For example, the CGM device can provide a user-operable interface on which the user can input the current scene, or the interface can include multiple selectable scenes, allowing the user to choose the current scene. Here, the user's selection of the current scene can also be considered user input.
[0181] Taking the user inputting their current scenario on the interface as an example, in response to the user's input of the scenario, the CGM device can determine the user's current scenario and then determine the second time period based on the scenario. For example, taking the user's current scenario as a fast carbon scenario, the user can input text such as "fast carbon scenario" on the interface displayed by the CGM device, and the CGM device can determine the second time period corresponding to the fast carbon scenario, such as 3 minutes.
[0182] Taking a user selecting a scene on the interface as an example, the interface may include at least one selection control. The selection control indicates a scene corresponding to the output strategy, and the user can select the scene they are in. In response to the user's operation of selecting a scene on the interface (i.e., the user's operation on the selection control), the CGM device can determine the scene the user is in, and then determine the second time period based on the scene the user is in.
[0183] In some embodiments, at least one type of scene detection unit may be deployed on the CGM device, and the CGM device can determine the scene in which the user is located based on the data collected by the scene detection unit.
[0184] For example, the scene detection unit may include a positioning unit for determining the user's location. For instance, the positioning unit may be a Global Positioning System (GPS). In this example, the CGM device can determine the user's scene based on the user's location collected by the positioning unit. For example, if the user's location is a restaurant, the CGM device can determine that the user's scene is a dining scene. Similarly, if the user's location is a gym or playground, the CGM device can determine that the user's scene is a sports scene.
[0185] For example, the scene detection unit may include a camera for capturing images. In this example, the CGM device can determine the scene in which the user is located based on the images captured by the camera. For instance, if the images captured by the camera include a restaurant, the CGM device can determine that the scene in which the user is located is a dining scene. Similarly, if the images captured by the camera include a gym, the CGM device can determine that the scene in which the user is located is a sports scene.
[0186] Furthermore, the CGM device can combine images captured by a camera to further define more specific scenarios. For example, in an eating scenario, the camera can capture images of the food, and the CGM device can determine whether the eating scenario is a fast-carb or slow-carb scenario based on these images. For instance, if the food image includes high-calorie foods such as cola and fried chicken, the CGM device can determine the eating scenario as a fast-carb scenario. Conversely, if the food image includes low-calorie foods such as whole grains, the CGM device can determine the eating scenario as a slow-carb scenario.
[0187] For example, the scene detection unit may include an inertial measurement unit (IMU). The CGM device can determine the scene in which the user is located based on the data collected by the IMU. The IMU may include, but is not limited to, accelerometers, gyroscopes, magnetometers, etc. Different scenes result in different actions performed by the user. The CGM device can determine the user's actions based on the data collected by the IMU, and thus determine the scene in which the user is located.
[0188] For example, when a user is in an eating scenario, their actions might involve repeatedly raising their arm and rotating their wrist. When the CGM device determines, based on data collected by the IMU, that the user's actions are "repeatedly raising their arm and rotating their hand," the CGM device can determine that the user is in an eating scenario. Similarly, the CGM device can also determine, based on data collected by the IMU, that the user is in an exercise scenario, such as a sprinting scenario or a jogging scenario. This application's embodiments do not exhaustively list all user actions in each scenario.
[0189] In addition, in some embodiments, the CGM device can combine multiple types of scene detection units to determine the user's scene, thereby improving the accuracy of scene determination. For example, if the positioning unit determines the user's location is a restaurant and the camera captures images of food, the CGM device can determine that the user's scene is an eating scene. For example, if the positioning unit determines the user's location is a gym and the CGM device determines the user is jogging based on data collected by the IMU, the CGM device can determine that the user's scene is an exercise scene, and specifically a jogging scene. It should be understood that the embodiments of this application do not exhaustively list examples of combining multiple types of scene detection units to determine a scene.
[0190] In summary, the second time period can be preset, user-defined, or determined by the CGM device based on the user's scenario. On the one hand, the embodiments of this application provide various ways to set the second time period, which can adapt to user habits and improve user experience. On the other hand, setting a second time period that is more suitable for the user can improve the accuracy and timeliness of blood glucose detection.
[0191] As described in the above embodiments, users can set a second time period in the CGM device, and the CGM device can determine the second time period based on the user's scenario. In some embodiments, in scenarios where the CGM device is connected to a terminal device, users can set a second time period on the terminal device, or the terminal device can determine the second time period based on the user's scenario. After determining the second time period, the terminal device can synchronize the second time period with the CGM device so that the CGM device can determine the second time period.
[0192] In this scenario, the CGM device can establish a wireless connection with at least one terminal device. For example, referring to Figure 7A, the CGM device can establish a wireless connection with a mobile phone and / or a watch. Taking the wireless connection between the CGM device and a mobile phone as an example, the user can set a second time period on the mobile phone, or the mobile phone can determine the second time period based on the user's current situation. After determining the second time period, the mobile phone can synchronize the second time period with the CGM device so that the CGM device can also determine the second time period.
[0193] The following example illustrates the interaction between a mobile phone and a CGM device. It's important to understand that the following examples use the CGM device calculating a user's blood glucose level as an example for explanation:
[0194] Method 1:
[0195] 1) Users set up a value output strategy on their mobile phones, and the value output strategy corresponds to a second time period.
[0196] In some embodiments, the mobile phone may provide a settings interface. For example, the mobile phone may provide a settings interface that includes settings options for a second time period. User interaction with these second time period settings options triggers the display of a first interface. The user can set the second time period on this first interface. For instance, the first interface may include at least one output strategy, each output strategy corresponding to a second time period. In other words, the first interface may include at least one selection control used to indicate the output strategy. Each output strategy may correspond to a different second time period. In this example, in response to the user's selection of an output strategy, the mobile phone can determine the second time period.
[0197] For example, referring to Figure 7B(a), the mobile phone can display a settings interface 701, which may include multiple settings options, including a second time period setting option 71. When the user operates the second time period setting option 71, the mobile phone can display a first interface 702. Referring to Figure 7B(b), the first interface 702 may include at least one output strategy, such as output strategy 1, output strategy 2, and output strategy 3. The second time period corresponding to output strategy 1 is 3 minutes, the second time period corresponding to output strategy 2 is 5 minutes, and the time period corresponding to output strategy 3 is 7 minutes. When the user selects output strategy 1, the mobile phone can determine that the output strategy is output strategy 1 and that the second time period corresponding to output strategy 1 is 3 minutes.
[0198] In some embodiments, when a mobile phone is wirelessly connected to a CGM device, the mobile phone can synchronize the user-selected output strategy, such as output strategy 1, to the CGM device. Alternatively, the mobile phone can synchronize the second time period "3min" corresponding to output strategy 1 to the CGM device. In this example, in response to the information synchronized by the mobile phone, the CGM device can determine that the second time period corresponding to output strategy 1 is "3min". The CGM device can delay collecting the glucose concentration of the interstitial fluid for 3 minutes; that is, the CGM device can obtain the blood glucose level at the first moment based on the first glucose concentration of the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the glucose concentration 3 minutes after the first moment. In this example, after obtaining the blood glucose level at the first moment, the CGM device can send the blood glucose level at the first moment to a terminal device (such as a mobile phone), causing the terminal device to display the blood glucose level at the first moment.
[0199] In summary, different output strategies correspond to different second time periods. When the second time period is 0, the output strategy can be described as real-time output, meaning the CGM device can obtain the blood glucose level at the first moment based on the first glucose concentration of the interstitial fluid at the first moment and the second glucose concentration within the first time period. In this example, the CGM device does not need to collect the glucose concentration of the interstitial fluid for a period of time after the current moment (such as the second time period). When the second time period is greater than 0, the output strategy can be described as delayed output, meaning the CGM device can obtain the blood glucose level at the first moment based on the first glucose concentration of the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the third glucose concentration within the second time period.
[0200] 2) Users set output strategies on their mobile phones; different output strategies result in different output strategies.
[0201] In some embodiments, the mobile phone can provide different application scenarios, and the output strategy varies depending on the application scenario. In other words, the application scenario corresponds to the output strategy.
[0202] For example, consider application scenarios including professional and personalized scenarios. In a professional scenario like a hospital setting, where high accuracy of blood glucose readings is required, a delayed output strategy could be used. Delayed output refers to collecting the glucose concentration of interstitial fluid over a period after the current moment. This allows the CGM device to combine the current moment with the glucose concentration of interstitial fluid over a period before and after the current moment to obtain the current blood glucose level, thereby improving accuracy.
[0203] In this example, for users with abnormal blood sugar levels, such as diabetic or hypoglycemic users, the user can select a specialized scenario so that the CGM device can obtain accurate blood sugar levels.
[0204] In some embodiments, when a user requires rapid blood glucose readings, the user can select a personalized scenario. In one possible implementation, the reading strategy corresponding to the personalized scenario can be real-time reading. Real-time reading refers to obtaining the current blood glucose level using the glucose concentration of interstitial fluid at the current moment and a period of time prior to the current moment. The CGM device can combine the current moment's glucose concentration with the interstitial fluid glucose concentration from the period of time prior to the current moment to obtain the current blood glucose level. With the real-time reading strategy, the CGM device does not need to delay collecting interstitial fluid glucose concentration data for a period of time after the current moment, resulting in rapid blood glucose readings and enabling real-time readings.
[0205] To improve user experience and accommodate different output needs, in some embodiments, personalized scenarios can also provide different output strategies for users to choose from, as described in the following embodiments.
[0206] The following provides further explanation for professional and personalized scenarios:
[0207] 1. Professional Scenarios
[0208] In some embodiments, a blood glucose monitoring application (APP) can be deployed on the mobile phone, and the APP's settings interface can provide the selection of application scenarios. For example, the settings interface may include output value setting options; user operation of these options can trigger the display of a second interface 801 on the mobile phone. Referring to Figure 8a, the second interface 801 may include an identifier for at least one application scenario, where the application scenario identifier is represented by its name in Figure 8a. Figure 8a uses the example of application scenarios including professional scenarios and personalized scenarios, where professional scenarios and personalized scenarios can correspond to different output value strategies.
[0209] For example, when a user operates in a professional scenario, the mobile phone can determine that the output strategy corresponding to the professional scenario is "delayed output by X minutes". Referring to Figure 8b, when the mobile phone and the CGM device are connected, the mobile phone can send the output strategy "delayed output by X minutes" to the CGM device. Correspondingly, the CGM device can detect blood glucose according to the output strategy "delayed output by X minutes". Specifically, the CGM device can obtain the blood glucose at the first moment based on the first glucose concentration of the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the glucose concentration X minutes after the first moment. Here, X minutes can be used as the second time period, and the glucose concentration within X minutes can be used as the third glucose concentration. After the CGM device obtains the blood glucose at the first moment, the CGM device can send the blood glucose at the first moment to the mobile phone so that the mobile phone can display the blood glucose at the first moment.
[0210] In some embodiments, to facilitate users' (such as doctors or researchers) understanding of the impact of delayed and real-time output on the accuracy of blood glucose testing, the output strategy is also used to indicate comparative testing. Comparative testing refers to the CGM device calculating blood glucose at a first time point using both delayed and real-time output strategies. The blood glucose calculated at the first time point using the delayed output strategy can be referred to as the first blood glucose. For example, the CGM device can obtain the first blood glucose based on the first glucose concentration in the interstitial fluid at the first time point, the second glucose concentration within a first time period, and the glucose concentration X minutes after the first time point. The blood glucose calculated at the first time point using the real-time output strategy can be referred to as the second blood glucose. For example, the CGM device can obtain the second blood glucose based on the first glucose concentration in the interstitial fluid at the first time point and the second glucose concentration within a first time period.
[0211] For example, the first blood glucose level can be blood glucose 1 as shown in Figure 8b, and the second blood glucose level can be blood glucose 2 as shown in Figure 8b. After acquiring blood glucose 1 and blood glucose 2, the CGM device can send blood glucose 1 and blood glucose 2 to the mobile phone, and the mobile phone can display blood glucose 1 and blood glucose 2. It should be understood that because the CGM device can continuously acquire the user's blood glucose, it can continuously send the first blood glucose and the second blood glucose to the mobile phone, and the mobile phone can display the curve of the first blood glucose (blood glucose 1) and the curve of the second blood glucose (blood glucose 2), as shown in Figure 8b.
[0212] 2. Personalized scenarios
[0213] In some embodiments, the output strategy corresponding to a personalized scenario can be real-time output. In this example, the CGM device can obtain the blood glucose level at a first moment based on the first glucose concentration of the interstitial fluid at a first moment and the second glucose concentration within a first time period.
[0214] In some embodiments, to meet users' personalized needs, multiple output strategies can be provided in the personalized scenario for users to choose from. Users can select the corresponding output strategy according to their blood glucose testing needs. For example, the personalized scenario may include at least one of the following output strategies: real-time output, delayed output, delayed output for historical time period, delayed output for fixed time period, delayed output during the rising phase, and delayed output during the falling phase.
[0215] Real-time output refers to obtaining the blood glucose level at the current moment by using the glucose concentration of interstitial fluid over a historical period and at the current moment. Because it eliminates the need for delaying the acquisition of glucose concentration in interstitial fluid over a period after the current moment, the blood glucose detection speed is fast.
[0216] In some embodiments, the real-time output strategy is suitable for scenarios where users have low requirements for the accuracy of blood glucose testing and need rapid output.
[0217] Delayed output refers to obtaining the blood glucose level at the current moment by using the glucose concentration of interstitial fluid at the current moment and a period of time before and after the current moment. Because the glucose concentration of the interstitial fluid is collected over a period of time after the current moment, the glucose concentration of the interstitial fluid is close to that of blood glucose, thus resulting in high accuracy in blood glucose detection.
[0218] In some embodiments, the delayed output strategy is suitable for scenarios where users have high requirements for the accuracy of blood glucose testing, such as professional scenarios.
[0219] Historical time period delayed output refers to using a delayed output strategy to obtain blood glucose data for a historical time period. In some embodiments, a user ate between 7:30 and 8:00 yesterday and used a CGM device to monitor blood glucose during the meal. For example, if the user forgot to connect their terminal device to the CGM device yesterday, the CGM device could not provide blood glucose data for display. After connecting the CGM device and the terminal device, the user can choose the historical time period delayed output strategy to view their blood glucose data from 7:30 to 8:00 yesterday, allowing the CGM device to obtain the blood glucose data from that time. Here, 7:30 to 8:00 yesterday can be considered the historical time period.
[0220] Understandably, because the user wears the CGM device continuously, it can acquire the glucose concentration of interstitial fluid at various times. For each moment within a historical time period, the CGM device can use that time period as the current moment and employ a delayed output strategy to acquire the blood glucose level at each moment within that historical time period. The blood glucose level for the historical time period can include the blood glucose levels at each moment within that historical time period. In this example, the user can view their blood glucose levels at any time, ensuring they are aware of any changes in their blood glucose levels over that historical period.
[0221] Fixed-time delayed output refers to obtaining a user's blood glucose levels within a fixed time period, using a delayed output strategy. This fixed time period can be daily, weekly, or monthly. For example, if a user's meal times are relatively fixed each day, and because meals cause a rise in blood glucose, a delayed output strategy can be used to monitor blood glucose levels during these fixed meal times. For instance, a user's daily meal times could be 7:30-8:00, 12:00-12:30, and 17:30-18:00. These three periods can be considered fixed time periods within the daily routine. In this example, a delayed output strategy can be used to obtain the user's blood glucose levels within these fixed time periods, allowing the user to know their blood glucose changes during the time they are interested in.
[0222] In some embodiments, the value output with a fixed time delay can also be referred to as the value output with a periodic time delay.
[0223] Delayed output during the rising phase refers to using a strategy of delaying the output of blood glucose data during the rising phase of blood glucose levels. In some embodiments, a first threshold can be preset. When the rate of increase in blood glucose is greater than or equal to the first threshold, it can be determined that blood glucose is in the rising phase. For example, the first threshold could be 0.056 mM / min. That is, the strategy of delaying output can be activated to determine the user's blood glucose level once it is determined that blood glucose is in the rising phase. This allows the user to accurately obtain information about the rise in blood glucose, so that if the rise in blood glucose exceeds the abnormal range, timely measures can be taken to lower blood glucose and ensure user safety.
[0224] Delayed output during the blood glucose decline phase refers to using a strategy of delaying the output of blood glucose data during the blood glucose decline phase. In some embodiments, a second threshold can be preset. When the rate of blood glucose decline is greater than or equal to the second threshold, it can be determined that blood glucose is in the decline phase. In other words, the strategy of delaying output can be activated to determine the user's blood glucose once it is determined that blood glucose is in the decline phase. This allows the user to accurately obtain information about the decline in blood glucose, so that if the decline in blood glucose exceeds the abnormal range, timely measures can be taken to raise blood glucose to ensure the user's safety.
[0225] The first threshold may be equal to or different from the second threshold.
[0226] Understandably, for the output strategies of "delayed output for historical time periods, delayed output for fixed time periods, delayed output during the rising phase, and delayed output during the falling phase," the output strategy is also used to indicate the detection time period. The detection time period can be: a historical time period, a periodic time period, a blood glucose rising phase, or a blood glucose falling phase, respectively.
[0227] It should be understood that the blood glucose output strategy in this application embodiment is for illustrative purposes only and does not exhaustively cover all situations. In some embodiments, the blood glucose output strategy can be customized according to the user's needs.
[0228] In this embodiment of the application, for delayed output values, historical time period delayed output values, fixed time period delayed output values, rising phase delayed output values, and falling phase delayed output values, the delayed output values require the CGM device to delay collecting the interstitial fluid glucose concentration for a period of time (the second time period) after the current moment. The second time period can be preset or user-defined. The method for user-defined setting of the second time period for delayed output values can be found in the description in FIG9A.
[0229] The following examples illustrate how users operate their mobile phones and how the phones interact with the CGM device to detect blood glucose, using delayed output, historical time-period delayed output, and fixed time-period delayed output as examples:
[0230] 2-1. Delayed output value
[0231] Figure 9A(a) can be described with reference to Figure 8(a). Referring to Figure 9A(a), when a user operates a personalized scene, the mobile phone can display the personalized scene setting interface 901. Referring to Figure 9A(b), interface 901 can include the following output strategies: real-time output, delayed output, historical time period delayed output, fixed time period delayed output, rising phase delayed output, and falling phase delayed output. When a user selects the "delayed output" option, the mobile phone can display the delayed output setting interface 902. Referring to Figure 9A(c), in interface 902, the user can customize the second time period for the delayed output; Figure 9A(c) uses a user-defined second time period of 3 minutes as an example. After the user sets the output strategy, when the mobile phone is connected to the CGM device, referring to Figure 9A(d), the mobile phone can send the output strategy "delayed output, and the second time period is 3 minutes" to the CGM device. In other words, the output strategy can also be called "3-minute delayed output".
[0232] The CGM device can detect blood glucose according to the output strategy and send the blood glucose data back to the mobile phone. Correspondingly, the mobile phone can display the blood glucose level. It is understandable that because the CGM device can continuously detect the user's blood glucose, it can continuously send the user's blood glucose data to the mobile phone, and the mobile phone can display the blood glucose curve, as shown in d of Figure 9A.
[0233] Corresponding to Figure 9A, Figure 9B illustrates the process of user operation of the mobile phone and interaction between the mobile phone and the CGM device in the form of a flowchart:
[0234] Referring to Figure 9B, for a mobile phone, the user can set the output policy on the phone. For example, Figure 9B shows the user selecting "delay output for 3 minutes" as the output policy. In some embodiments, the APP can also provide an interface for the user to set the time period during which the output policy takes effect. Figure 9B shows an example where the user has not set a time period.
[0235] Referring to Figure 9B, after the user sets the output strategy, when the mobile phone is connected to the CGM device, the mobile phone can send the output strategy of "delayed output for 3 minutes" to the CGM device. Accordingly, in order to obtain the blood glucose at the first moment (e.g., the current moment), the CGM device can delay the collection of physiological data for 3 minutes. It can be understood that because the user is constantly wearing the CGM device, the CGM device can collect the second physiological data within the first time period, the first physiological data at the first moment, and the CGM device can also delay the collection of the third physiological data within the second time period. The second time period is 3 minutes.
[0236] As described in the above embodiment S601, the CGM device can obtain the second glucose concentration of the interstitial fluid in the first time period based on the second physiological data in the first time period, the CGM device can obtain the first glucose concentration of the interstitial fluid in the first time period based on the first physiological data in the first time period, and the CGM device can obtain the third glucose concentration of the interstitial fluid in the second time period based on the third physiological data in the second time period.
[0237] The CGM device, based on its output strategy, obtains the blood glucose level at the first moment, according to the first glucose concentration in the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the third glucose concentration within the second time period. The CGM device can then send the blood glucose level at the first moment to a mobile phone. Similarly, for each moment after the first moment, the CGM device can also obtain the blood glucose level at the current moment based on the glucose concentration in the interstitial fluid at the current moment, as well as the glucose concentration over a period of time before and after the current moment.
[0238] 2-2. Delayed output of historical time periods
[0239] Figure 10A's ab can be compared to the description in Figure 9A's ab. In one possible scenario, when a user needs to view blood glucose levels for a historical time period (e.g., yesterday 7:00-8:00), the user can select the "delayed output of historical data" strategy. Referring to Figure 10A's b, the user's operation of the "delayed output of historical data" option triggers the phone to display the interface 1001 for setting the delayed output of historical data. Referring to Figure 10A's c, in interface 1001, the user can customize the time period. Figure 10A's c uses the user-defined time period of "7:00-8:00" as an example. After the user sets the output strategy, referring to Figure 10A's d, the phone can send the output strategy of "delayed output of historical data, with the time period being 7:00-8:00" to the CGM device. The CGM device can employ a delayed output strategy to detect blood glucose levels during historical time periods (e.g., 7:00-8:00 yesterday) and send these historical time periods (e.g., 7:00-8:00 yesterday) to a mobile phone. The mobile phone can then display the blood glucose levels for that historical time period, as shown in e of Figure 10A.
[0240] Corresponding to Figure 10A, Figure 10B illustrates the process of user operation of the mobile phone and interaction between the mobile phone and the CGM device in the form of a flowchart:
[0241] Referring to Figure 10B, for a mobile phone, the user can set the output strategy on the phone. For example, in Figure 10B, the user selects the output strategy as "delayed output for historical time period" and the user also sets the corresponding time period.
[0242] Referring to Figure 10B, after the user sets the output strategy, the mobile phone can send the output strategy of "delayed output for historical time period" and the corresponding time period to the CGM device. Accordingly, the CGM device can detect blood glucose according to this output strategy. Specifically, the CGM device can determine the start time Ts (e.g., 7:00) and end time Te (e.g., 8:00) of the historical time period. For each time between the start time Ts and the end time Te, the CGM device can use the delayed output strategy to obtain the blood glucose at each time. After obtaining the blood glucose at each time of the historical time period, the CGM device can store the blood glucose at each time of the historical time period.
[0243] In some embodiments, the CGM device can send blood glucose levels at each moment of the historical time period to a mobile phone. Accordingly, the mobile phone can display the blood glucose levels at each moment of the historical time period, as shown in Figure 10C.
[0244] The examples in Figures 10A-10C illustrate that users can select a time period as the historical time period. In some embodiments, users do not need to select a historical time period, and the CGM device can use all the time before the current time or a preset time period before the current time as the historical time period.
[0245] In one possible scenario, the phone's interface can display an update control. If the CGM device uses a real-time output strategy to obtain blood glucose levels for each moment in a historical time period, and the user needs to update the historical blood glucose levels, the user can operate the update control. In response to the user's operation of the update control, the phone can instruct the CGM device to use a delayed output strategy to obtain blood glucose levels for each moment in the historical time period. Accordingly, the phone can receive and display the blood glucose levels for each moment in the historical time period from the CGM device.
[0246] In this example, the phone can also display a notification such as "Blood glucose updated." Additionally, if there are abnormal blood glucose levels over a historical period, the phone can also indicate the time of the abnormality to alert the user.
[0247] In one possible scenario, the phone's interface could display a first control for delayed value output and a second control for real-time value output. When the user selects the first control, the phone can instruct the CGM device to use a delayed value output strategy to obtain blood glucose levels at each moment within a historical time period. When the user selects the second control, the phone can instruct the CGM device to use a real-time value output strategy to obtain blood glucose levels at each moment within a historical time period.
[0248] In this scenario, the phone's interface can also display a third control for instructing comparative testing. When the user selects the third control, the phone can instruct the CGM device to use a delayed output strategy to obtain the first blood glucose level at each moment of the historical time period, and the phone can also instruct the CGM device to use a real-time output strategy to obtain the second blood glucose level at each moment of the historical time period. In this example, the CGM device can send the first blood glucose level and the second blood glucose level for each moment of the historical time period to the phone. Correspondingly, the phone can display a comparative analysis of the first and second blood glucose levels for each moment of the historical time period. In this example, the phone can also display a prompt message such as "The second blood glucose level is more accurate than the first blood glucose level."
[0249] 2-3. Delayed output of values within a fixed time period
[0250] Figure 11A's ab can be compared with the description of ab in Figure 9A. Referring to Figure 11A's b, when the user selects the "Fixed time period delayed output value" option, the phone will display the fixed time period delayed output value setting interface 1101. Referring to Figure 11A's c, in interface 1101, the user can customize the time period. Figure 11A's c uses the user-defined time periods as "7:00-8:00, 12:00-13:00, and 18:00-19:00" as an example. After the user sets the output value policy, when the phone is connected to the CGM device, referring to Figure 11A's d, the phone can send the output value policy to the CGM device as "Fixed time period delayed output value, and the time period is 7:00-8:00, 12:00-13:00, and 18:00-19:00".
[0251] The CGM device can detect blood glucose according to this output strategy and send the blood glucose data back to the mobile phone. Specifically, the CGM device can detect whether the current moment (e.g., the first moment) is within the time period indicated by the output strategy. If the current moment is within the time period indicated by the output strategy, the CGM device can adopt a delayed output strategy to detect the blood glucose at the current moment.
[0252] Corresponding to Figure 11A, Figure 11B illustrates the process of user operation of the mobile phone and interaction between the mobile phone and the CGM device in the form of a flowchart:
[0253] Referring to Figure 11B, for a mobile phone, the user can set the output strategy on the phone. For example, in Figure 11B, the user selects the output strategy as "delayed output for a fixed time period" and the user also sets the corresponding time period.
[0254] Referring to Figure 11B, after the user sets the output strategy, when the mobile phone is connected to the CGM device, the mobile phone can send the output strategy of "fixed time period delayed output" and the corresponding time period to the CGM device. Accordingly, the CGM device can detect blood glucose according to this output strategy. Specifically, in response to the current time being within the time period indicated by the output strategy, the CGM device can use a delayed output method to obtain the blood glucose at each moment within that time period.
[0255] In summary, as mentioned in 1) and 2) above, users can set output strategies on their terminal devices, and these strategies can be synchronized with the CGM device. The CGM device can then detect the user's blood glucose based on these strategies, adapting to different user needs and improving the user experience.
[0256] It is understandable that the CGM device can detect blood glucose based on the user-selected output strategy. For example, the CGM device can detect the user's blood glucose in a delayed output manner during historical time periods, fixed time periods, periods of rising blood glucose, or periods of falling blood glucose. In some embodiments, the CGM device can also detect the user's blood glucose in other time periods, such as non-historical time periods or non-fixed time periods, for example, by using a real-time output method.
[0257] In some embodiments, historical time periods, fixed time periods, blood glucose rising phases, and blood glucose falling phases can be referred to as the first detection time periods, and other time periods outside the first detection time periods can be referred to as the second detection time periods (such as non-historical time periods, non-fixed time periods, etc.).
[0258] It is understandable that when a user sets a reading strategy on their terminal device, and the CGM device and the terminal device are connected, the terminal device can synchronize the reading strategy with the CGM device. In one possible scenario, after the terminal device synchronizes the reading strategy with the CGM device, if the terminal device and the CGM device disconnect, the CGM device will still use the reading strategy to detect blood glucose, and after the terminal device and the CGM device re-establish the connection, the CGM device can send the user's blood glucose data back to the terminal device.
[0259] Method 2:
[0260] In some embodiments, the mobile phone may provide a user-operable interface on which the user inputs the scene they are in, or the interface may include multiple scenes to be selected, allowing the user to choose the scene they are in. In this way, the mobile phone can determine the scene the user is in based on the user's input or selection, as described in the relevant description of CGM devices, which will not be repeated here.
[0261] In some embodiments, at least one type of scene detection unit can be deployed on the mobile phone. The CGM device can determine the scene in which the user is located based on the data collected by the scene detection unit. The method by which the mobile phone determines the scene in which the user is located can be referred to the relevant description of the CGM device described above, and will not be repeated here. In this example, different scenes can correspond to a value output strategy, which can be referred to the relevant description in Method 1. After determining the scene in which the user is located, the mobile phone can determine the value output strategy corresponding to the scene in which the user is located and synchronize the value output strategy with the CGM device.
[0262] For example, in a fast-carb scenario, the output strategy is delayed, and the second time period is 3 minutes. After the mobile phone identifies the user's current scenario as a fast-carb scenario, it can send the corresponding output strategy to the CGM device. The CGM device can then detect blood glucose based on this strategy. For instance, in a fast-carb scenario, the CGM device can obtain the blood glucose level at the first moment based on the first glucose concentration in the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the glucose concentration 3 minutes after the first moment. In this example, after obtaining the blood glucose level at the first moment, the CGM device can send this data to a terminal device (such as a mobile phone), allowing the terminal device to display the blood glucose level at the first moment.
[0263] As described in the above embodiments, the mobile phone can determine the user's current scenario and determine the output strategy based on that scenario. In some embodiments, when the mobile phone detects and determines the output strategy, it can also provide a function to remind the user to use a delayed output strategy to test blood glucose, thereby improving the user experience. Taking a user's current scenario as an eating scenario as an example, the output strategy corresponding to an eating scenario is a 3-minute delayed output. For example, referring to Figure 12a, when the mobile phone detects that the user's location is a restaurant, it can determine that the user's current scenario is an eating scenario, and the mobile phone can output a prompt message. This prompt message is used to prompt the user whether to start using the delayed output strategy to test blood glucose. For example, the mobile phone can display the prompt message on the interface or output the prompt message via voice broadcast.
[0264] Referring to Figure 12a, the mobile phone can display a prompt message such as "Start blood glucose testing with delayed output strategy?", along with "Yes" and "No" controls in the message notification bar on the negative one screen. The user can operate the "Yes" control to trigger the phone to start blood glucose testing. In response to the user's operation of the "Yes" control, the mobile phone can send a testing command to the CGM device, triggering the CGM device to start blood glucose testing. The testing command may include an output strategy. For example, the output strategy may indicate delayed output, with the second time period being 3 minutes.
[0265] In some embodiments, the mobile phone can also provide a reminder to enable the comparison detection function. After the user enables the comparison detection function, the CGM device can detect blood glucose according to the output strategy corresponding to the user's scenario, and can also detect blood glucose according to the real-time output method, enabling a comparison of two blood glucose levels.
[0266] In this example, after the user clicks the "Yes" control, the phone can prompt the user to enable the comparison detection function. For instance, referring to Figure 12b, the phone can display a prompt message asking "Enable comparison detection?", along with both a "Yes" control and a "No" control. The user clicking the "Yes" control triggers the phone to start blood glucose testing. In response to the user's click on the "Yes" control, the phone can send a detection command to the CGM device, triggering the CGM device to start blood glucose testing.
[0267] The detection command may include an output strategy. Referring to Figure 12c, the output strategy not only indicates the output value of the delay Ymin but also indicates comparative detection. For example, if the user's scenario is a fast carbon scenario, Y can be 3. In this example, in response to the detection command from the mobile phone, the CGM device can perform two calculations:
[0268] On one hand, the CGM device can perform calculations based on a "delayed Ymin value" strategy. That is, the CGM device can obtain the blood glucose level (e.g., blood glucose 1A) at the first moment based on the first glucose concentration of the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the third glucose concentration within the second time period (e.g., 3 minutes after the first moment). In some embodiments, the blood glucose level at the first moment (e.g., blood glucose 1A) can be used as the first blood glucose level.
[0269] On the other hand, the CGM device can perform calculations according to a "real-time output" strategy, that is, the CGM device can obtain the blood glucose level (e.g., blood glucose 2A) at a first moment based on the first glucose concentration of the interstitial fluid at a first moment and the second glucose concentration within a first time period. In some embodiments, the blood glucose level at the first moment (e.g., blood glucose 2A) can be used as the second blood glucose level.
[0270] After acquiring the first and second blood glucose levels, the CGM device can send these data to a mobile phone, which can then display them. It should be understood that because the CGM device can continuously acquire the user's blood glucose levels, it can continuously send the first and second blood glucose levels to the phone. The phone can display the curves for both the first and second blood glucose levels (glucose 1A and glucose 2A), as shown in Figure 12c. Additionally, the phone can display information such as "Comparative Detection" and "The accuracy of the curve for the first blood glucose level (glucose 1A) is improved compared to the second blood glucose level (glucose 2A)."
[0271] Figure 12 shows the curves of the first blood glucose (blood glucose 1A) and the second blood glucose (blood glucose 2A) in two separate graphs. In some embodiments, the mobile phone can also display the curves of the first blood glucose (blood glucose 1A) and the second blood glucose (blood glucose 2A) in one graph, as shown in Figure 13. This application embodiment does not limit the way the two blood glucose curves are compared and displayed.
[0272] In summary, in this embodiment, the user can set the output strategy on the terminal device, or the terminal device can determine the output strategy based on the user's scenario. After determining the output strategy, the terminal device can send the output strategy to the CGM device, which can then detect blood glucose according to the output strategy. This approach has wide applicability and can improve the user experience. Furthermore, allowing the user to set the output strategy on the terminal device, or for the terminal device to detect the user's scenario, simplifies the configuration of the CGM device.
[0273] Referring to the description of the blood glucose detection method in the above embodiments, the CGM device in this application embodiment has high accuracy in detecting blood glucose, which can ensure the safety of users with abnormal blood glucose levels.
[0274] In some embodiments, based on the blood glucose detection method provided in this application, the CGM device can detect the user's blood glucose at a first moment. When the blood glucose at the first moment is within an abnormal range, the CGM device can output a prompt message. This prompt message is used to alert the user to the abnormal blood glucose level at the first moment, thus enabling timely measures to raise or lower the user's blood glucose level and ensuring the user's safety.
[0275] In some embodiments, after the CGM device detects the user's blood glucose level at a first moment, the CGM device can send the blood glucose level at the first moment to the terminal device. When the blood glucose level at the first moment is within an abnormal range, the terminal device can output a prompt message and can also promptly remind the user of the abnormal blood glucose level at the first moment to ensure the user's safety.
[0276] For example, referring to the description in the above embodiments, in a scenario where the output strategy is used to indicate comparative detection, the CGM device can use a delayed output strategy to obtain the user's first blood glucose level and a real-time output strategy to obtain the user's second blood glucose level. Compared to the second blood glucose level, the detection accuracy of the first blood glucose level is higher. If the second blood glucose level is not within the abnormal range, but the first blood glucose level is within the abnormal range, the CGM device or terminal device can output a prompt message in a timely manner to remind the user of the abnormal blood glucose level.
[0277] For example, if the CGM device uses a real-time output strategy to obtain the user's second blood glucose level, and the user requires a delayed output strategy to update the second blood glucose level, the CGM device can use a delayed output strategy to obtain the user's first blood glucose level. Compared to the second blood glucose level, the first blood glucose level has higher detection accuracy. If the second blood glucose level is within the abnormal range, but the first blood glucose level is within the abnormal range, the CGM device or terminal device can promptly output a prompt message to remind the user of the abnormal blood glucose level.
[0278] Referring to the description in the above embodiments, the CGM device can obtain the blood glucose level at a first moment based on the first glucose concentration at a first moment, the second glucose concentration within a first time period, the third glucose concentration within a second time period, and processing parameters. In some embodiments, when sending the blood glucose level at the first moment to the terminal device, the CGM device can also send the first glucose concentration at the first moment, the second glucose concentration within the first time period, the third glucose concentration within the second time period, and processing parameters to the terminal device. This first glucose concentration at the first moment, the second glucose concentration within the first time period, the third glucose concentration within the second time period, and the processing parameters can form a set of data. During the user's use of the CGM device, the CGM device can continuously monitor the user's blood glucose level at multiple moments, and correspondingly, the terminal device can receive multiple sets of data from the CGM device.
[0279] In some embodiments, referring to FIG14, the terminal device can upload multiple sets of data to the cloud. The cloud can optimize processing parameters based on the user's multiple sets of data, so that the optimized processing parameters can make the glucose concentration in the interstitial fluid closer to blood glucose. After optimizing the processing parameters, the cloud can also provide feedback to the terminal device, and the terminal device can also send the optimized processing parameters to the CGM device, so that the CGM device can use the optimized processing parameters to detect blood glucose, further improving the accuracy of blood glucose detection.
[0280] It should be noted that the user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data used for analysis, data stored, data displayed, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties. Furthermore, the collection, use and processing of the relevant data must comply with the relevant laws, regulations and standards of the relevant countries and regions, and corresponding operation portals are provided for users to choose to authorize or refuse.
[0281] This application provides an electronic device, which can be a blood glucose monitoring device or a terminal device. The electronic device may include a processor and a memory, the memory for storing code instructions, and the processor for executing the code instructions to perform the method provided in this application.
[0282] This application provides a chip. The chip includes a processor, which is used to call a computer program in memory to execute the technical solutions in the above embodiments. Its implementation principle and technical effects are similar to those in the related embodiments described above, and will not be repeated here.
[0283] This application also provides a computer-readable storage medium. The computer-readable storage medium stores a computer program. When the computer program is executed by a processor, it implements the methods described above. The methods described in the above embodiments can be implemented wholly or partially by software, hardware, firmware, or any combination thereof. If implemented in software, the functionality can be stored as one or more instructions or code on or transmitted over the computer-readable medium. The computer-readable medium can include computer storage media and communication media, and can also include any medium that can transfer a computer program from one place to another. The storage medium can be any target medium accessible by a computer.
[0284] In one possible implementation, a computer-readable medium may include random access memory (RAM), read-only memory (ROM), compact disc read-only memory (CD-ROM) or other optical disc storage, magnetic disk storage or other magnetic storage devices, or any other medium intended to carry or store required program code in the form of instructions or data structures, and accessible by a computer. Furthermore, any connection is appropriately referred to as a computer-readable medium. For example, if software is transmitted from a website, server, or other remote source using coaxial cable, fiber optic cable, twisted pair, digital subscriber line (DSL), or wireless technologies such as infrared, radio, and microwave, then coaxial cable, fiber optic cable, twisted pair, DSL, or wireless technologies such as infrared, radio, and microwave are included in the definition of medium. As used herein, disks and optical discs include optical discs, laser discs, optical discs, digital versatile discs (DVDs), floppy disks, and Blu-ray discs, where disks typically reproduce data magnetically, while optical discs optically reproduce data using lasers. Combinations of the above should also be included within the scope of computer-readable media.
[0285] This application provides a computer program product, which includes a computer program that, when run, causes a computer to perform the above-described method.
[0286] It should be noted that the modules or components described in the above embodiments can be one or more integrated circuits configured to implement the above methods, such as one or more application-specific integrated circuits (ASICs), one or more digital signal processors (DSPs), or one or more field-programmable gate arrays (FPGAs), etc. Furthermore, when a module is implemented through processing element scheduler code, the processing element can be a general-purpose processor, such as a central processing unit (CPU) or other processors capable of calling program code, such as a controller. Additionally, these modules can be integrated together to implement a system-on-a-chip (SOC).
[0287] In the above embodiments, implementation can be achieved, in whole or in part, through software, hardware, firmware, or any combination thereof. When implemented in software, it can be implemented, in whole or in part, as a computer program product. A computer program product includes one or more computer instructions. When the computer program instructions are loaded and executed on a computer, all or part of the flow or function according to the embodiments of this application is generated. The computer can be a general-purpose computer, a special-purpose computer, a computer network, or other programmable device. The computer instructions can be stored in a computer-readable storage medium or transmitted from one computer-readable storage medium to another. For example, computer instructions can be transmitted from one website, computer, server, or data center to another website, computer, server, or data center via wired (e.g., coaxial cable, fiber optic, digital subscriber line (DSL)) or wireless (e.g., infrared, wireless, microwave, etc.) means. The computer-readable storage medium can be any available medium that a computer can access or a data storage device such as a server or data center that integrates one or more available media. The available medium can be a magnetic medium (e.g., floppy disk, hard disk, magnetic tape), an optical medium (e.g., DVD), or a semiconductor medium (e.g., a solid-state disk (SSD)).
[0288] In the embodiments of the present application, terms such as "first" and "second" are used to distinguish identical or similar items with basically the same functions and effects. For example, the first numerical value and the second numerical value are only used to distinguish different numerical values, and do not limit their sequence. Those skilled in the art can understand that terms such as "first" and "second" do not limit the quantity and execution order, and terms such as "first" and "second" do not necessarily limit being different.
[0289] It should be noted that in the embodiments of the present application, words such as "exemplarily" or "for example" are used to give examples, illustrations or explanations. Any embodiment or design solution described as "exemplarily" or "for example" in the present application should not be construed as being more preferred or having more advantages than other embodiments or design solutions. Exactly speaking, the use of words such as "exemplarily" or "for example" aims to present relevant concepts in a specific manner.
[0290] In the embodiments of the present application, "at least one" means one or more, and "multiple" means two or more. "And / or" describes the association relationship of associated objects and indicates that three relationships can exist. For example, "A, and / or, B" can represent: A exists alone, A and B exist simultaneously, and B exists alone, where A and B can be singular or plural. The character " / " generally indicates that the front and rear associated objects have an "or" relationship. "At least one (item)" or its similar expression refers to any combination of these items, including any combination of single item (item) or plural items (items). For example, at least one (item) of a, b, or c can represent: a, b, c, a - b, a - c, b - c, or a - b - c, where a, b, c can be single or multiple. It can be understood that in the embodiments of the present application, the various numerical numbers involved are only for the convenience of description and do not limit the scope of the embodiments of the present application.
[0291] It can be understood that in the embodiments of the present application, the magnitudes of the sequence numbers of the above processes do not mean the sequence of execution order. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation to the implementation process of the embodiments of the present application.
Claims
1. A blood glucose detection method, characterized in that, Applied to a first device, the method includes: The first glucose concentration of interstitial fluid at a first moment, the second glucose concentration during a first time period, and the third glucose concentration during a second time period are obtained. The first time period is the period from the second moment to the first moment, and the second moment is earlier than the first moment. The second time period is the period from the first moment to the third moment, and the third moment is later than the first moment. The blood glucose level at the first moment is output based on the first glucose concentration, the second glucose concentration, and the third glucose concentration.
2. The method according to claim 1, characterized in that, The duration of the second time period is a preset duration; or, The duration of the second time period is a user-defined duration; or, The duration of the second time period is related to the scenario in which the user is located.
3. The method according to claim 2, characterized in that, When the duration of the second time period is a user-defined duration, the method further includes: The first interface is displayed, which includes at least one output strategy, and each output strategy corresponds to a second time period. In response to the user's selection of the output value strategy, the second time period is determined.
4. The method according to claim 2, characterized in that, When the duration of the second time period is related to the user's scenario, the method further includes: Based on the collected scene-related data, determine the scene in which the user is located; or, The user's current scenario is determined based on user input; The second time period is determined based on the user's current situation.
5. The method according to claim 4, characterized in that, The first device includes a scene detection unit, which includes at least one of the following: a positioning unit, a camera, and an inertial measurement unit. The scene-related data is data collected by the scene detection unit.
6. The method according to claim 1 or 2, characterized in that, The first device is connected to the second device, and the method further includes: Receive output policy from the second device, the output policy being used to indicate the second time period.
7. The method according to claim 6, characterized in that, The output of the blood glucose at the first moment includes: The blood glucose level at the first moment is sent to the second device, so that the second device displays the blood glucose level at the first moment.
8. The method according to claim 3 or 6, characterized in that, The output strategy is also used to indicate a first detection time period, where the first moment is included in the first detection time period.
9. The method according to claim 8, characterized in that, The first detection time period can be a historical time period, a periodic time period, a blood glucose rising phase, or a blood glucose falling phase.
10. The method according to claim 3 or 6, characterized in that, The blood glucose level at the first moment is the first blood glucose level, and the method further includes: The second blood glucose level at the first time point is determined based on the first glucose concentration and the second glucose concentration; The output of the blood glucose level at the first moment includes: Output the first blood glucose level and the second blood glucose level.
11. The method according to claim 10, characterized in that, The first blood glucose level is within the abnormal range, while the second blood glucose level is not within the abnormal range.
12. The method according to any one of claims 1-11, characterized in that, The method further includes: When the blood glucose level at the first moment is within the abnormal range, a first prompt message is output, which is used to notify the user that the blood glucose level at the first moment is abnormal.
13. The method according to claim 8 or 9, characterized in that, The method further includes: The fourth glucose concentration of the interstitial fluid at the fourth time point and the fifth glucose concentration during the third time period are obtained. The third time period is the time period from the fifth time point to the fourth time point. The fifth time point is earlier than the fourth time point. The fourth time point is included in the second detection time period. The second detection time period does not overlap with the first detection time period. Based on the fourth glucose concentration and the fifth glucose concentration, the blood glucose level at the fourth time point is output.
14. The method according to any one of claims 1-13, characterized in that, Before obtaining the first glucose concentration of the interstitial fluid at the first moment, the second glucose concentration within the first time period, and the third glucose concentration within the second time period, the method further includes: Collect the first physiological data of the interstitial fluid at the first moment, the second physiological data within the first time period, and the third physiological data within the second time period; The acquisition of the first glucose concentration in the interstitial fluid at a first moment, the second glucose concentration within a first time period, and the third glucose concentration within a second time period includes: Based on the first physiological data, obtain the first glucose concentration of the interstitial fluid at the first moment; Based on the second physiological data, the second glucose concentration of the interstitial fluid during the first time period is obtained; Based on the third physiological data, the third glucose concentration of the interstitial fluid during the second time period is obtained.
15. A blood glucose detection method, characterized in that, Applied to a first device, the method includes: Receive blood glucose testing instructions immediately; The first glucose concentration, the second glucose concentration, and the third glucose concentration in the interstitial fluid at the first time point, the first time point being the period from the second time point to the first time point, the second time point being earlier than the first time point, the second time point being the period from the first time point to the third time point, and the third time point being later than the first time point are obtained. Based on the first glucose concentration, the second glucose concentration, and the third glucose concentration, the blood glucose level at the first time point is output at the sixth time point, wherein the sixth time point is no earlier than the third time point.
16. The method according to claim 15, characterized in that, The method further includes: Display a first interface, the first interface including at least one selection control, the selection control is used to indicate a value output strategy or to indicate a scenario corresponding to the value output strategy, a value output strategy corresponds to a second time period; The second time period is determined in response to the user's operation on the selection control.
17. The method according to claim 16, characterized in that, The scenario is any one of the following: eating scenario, exercising scenario, fasting scenario, or sleeping scenario.
18. The method according to any one of claims 15-17, characterized in that, The blood glucose level at the first moment is the first blood glucose level, and the method further includes: The second blood glucose level at the first time point is determined based on the first glucose concentration and the second glucose concentration; The output of the blood glucose level at the first moment includes: At the sixth time point, the first blood glucose level is output, and at the seventh time point, the second blood glucose level is output, wherein the seventh time point is earlier than the sixth time point.
19. The method according to claim 16 or 17, characterized in that, When the selection control is used to indicate a scenario corresponding to the output strategy, in response to the user's operation on the selection control, the method further includes: Output a second prompt message, which prompts the user whether to start blood glucose testing using the output strategy; In response to the user's confirmation, the blood glucose level is detected using the output strategy.
20. The method according to claim 19, characterized in that, Before using the aforementioned output strategy to detect blood glucose, the method further includes: Output a third prompt message, which is used to prompt the user whether to enable comparison detection; In response to the user's confirmation, the second blood glucose level at the first moment is determined based on the first glucose concentration and the second glucose concentration. The blood glucose level at the first moment is the first blood glucose level, and the output of the blood glucose level at the first moment includes: At the sixth time point, the first blood glucose level is output, and at the seventh time point, the second blood glucose level is output, wherein the seventh time point is earlier than the sixth time point.
21. The method according to claim 18 or 20, characterized in that, The method further includes: A fourth prompt message is output, which indicates that the accuracy of the first blood glucose level is higher than that of the second blood glucose level.
22. An electronic device, characterized in that, The electronic device includes: one or more processors and memory; The memory is coupled to the one or more processors, the memory being used to store computer program code, the computer program code including computer instructions, the one or more processors invoking the computer instructions to cause the electronic device to perform the method as described in any one of claims 1-21.
23. A chip system, characterized in that, The chip system is applied to an electronic device, the chip system including one or more processors, the one or more processors being used to invoke computer instructions to cause the electronic device to perform the method as described in any one of claims 1-21.
24. A computer-readable storage medium, characterized in that, The computer-readable storage medium includes computer instructions that, when executed on an electronic device, cause the electronic device to perform the method as described in any one of claims 1-21.
25. A computer program product, characterized in that, The computer program product includes computer program code that, when run on an electronic device, causes the electronic device to perform the method as described in any one of claims 1-21.