Customizable patient monitoring device and system

Abstract

Patient monitoring devices, systems and methods are provided. A customizable patient monitoring device may include multiple ports allowing connection and disconnection of any of various physiological sensors. Signals from physiological sensors may be processed to obtain clinically presentable physiological information, which may include accessing the information from the signals or computing the information based at least in part on the signals. An arrangement of display units may be displayed on a monitoring device display of the customizable patient monitoring device, such as a grid of tiles, in which each tile may display information associated with a specific physiological parameter associated with a specific connected physiological sensor. A tile may be actuated by touch to display an enhanced display on the monitoring device display displaying additional information associated with the specific physiological parameter. The enhanced display may be actuated by touch to provide further information associated with the specific physiological parameter.

Description

Attorney Docket No. Z20886WO-01CUSTOMIZABLE PATIENT MONITORING DEVICE AND SYSTEMCROSS-REFERENCE TO RELATED APPLICATION

[0001] This application claims priority to U.S. Provisional Application No. 63 / 760,281, filed on February 19, 2025, entitled, “CUSTOMIZABLE PATIENT MONITORING DEVICE AND SYSTEM.”BACKGROUND

[0002] Patient monitoring is needed, for example, in a diverse range of clinical environments, clinical conditions, levels or stages of patient care, patient populations, and levels of care provider expertise. However, individual care providers in specific clinical situations have particular patient monitoring requirements. Additionally, size and weight of a customizable patient monitoring device can be significant factors in patient care, particularly, for example, in prehospital care, where emergency medical equipment may need to be carried by a care provider to the location of the patient. Furthermore, clinical monitoring requirements may change during ongoing patient care, such as through changing levels or stages of care. For example, clinical monitoring requirements may change or increase from emergency7field care to later care, whether during care by one or more care providers, or potentially across changing care providers (e.g., an emergency care provider providing care at the scene of a patient immediately following a patient injury or medical event, then a paramedic providing care during later patient transport, etc.). Still further, in various situations, such as during pre-hospital care, ease, speed, and relative simplicity7in patient monitoring may be important factors in optimizing patient care. As such, factors including, for example, a broad range of patient monitoring needs and uses, varying individual situationdependent needs, potentially changing patient monitoring needs over time during care of a patient, and size and weight considerations can pose many challenges in patient monitoring, including in critical, life-saving clinical care situations.SUMMARY

[0003] One example provides a medical monitoring device for monitoring of a patient during treatment of the patient, comprising: a monitoring device display; a plurality' of dynamically configurable ports, each configured to allow connection of any of a plurality7of connectable physiological sensors, and each configured to allow connection of a physiological sensor of a plurality of physiological sensors connected to the medical monitoring device for monitoring of the patient, the medical monitoring device configuredAttorney Docket No. Z20886WO-01such that each of the plurality of physiological sensors is selectable by a user of the medical monitoring device at least in part by connection, to some or all of the plurality of dynamically configurable ports, of each of the plurality of physiological sensors; at least one processor and at least one memory, the at least one memory comprising a monitoring director configured to be executable by the at least one processor in: receiving signals from each of the plurality of physiological sensors, processing the received signals to obtain, for each of the plurality of physiological sensors, clinically presentable physiological information comprising a specific physiological parameter and a magnitude for the specific physiological parameter, comprising: if the information is accessible from the received signals, accessing the information from the received signals, and if the information is not accessible from the received signals, computing the information based at least in part on the received signals, displaying, on the monitoring device display, an arrangement of display units, each occupying a portion of an area of the monitoring device display, each configured to be associated with a specific physiological sensor of the plurality of physiological sensors, and each configured to display the information associated with the specific physiological sensor, and upon actuation relating to a first display unit of the arrangement of display units, cause display, on the monitoring device display, of a first enhanced display associated with the first display unit, the first enhanced display replacing at least some of the display units of the arrangement of display units, and the first enhanced display displaying additional information associated with the specific physiological parameter associated with the first display unit, the additional information being in addition to the information displayed by the first display unit.

[0004] In some examples, the plurality’ of connectable physiological sensors comprises physiological sensors for enabling measurement of non-invasive blood pressure (NIBP), systolic blood pressure, diastolic blood pressure, mean arterial pressure (MAP), invasive blood pressure (IBP), pulse rate (PR), pulse pressure variation (PPV), respiratory rate (RR), end-tidal carbon dioxide (EtCO2), capnogram waveform, oxygen saturation (SpO2), photoplethysmography (PPG) waveform, a hypovolemia compensation measurement, inspiratory’ volume (Vi), expiratory volume (Ve), peak inspiratory pressure (PIP), temperature, heart rate (HR), ECG waveform, heart rate variability (HRV), and amplitude spectrum area (AMSA). In some examples, the plurality of connectable physiological sensors comprises a non-invasive blood pressure (NIBP) sensor, an invasive blood pressure (IBP) sensor, a capnograph, a pulse oximeter, a sensor that senses flow rate, a sensor that senses pressure, a temperature sensor, and one or more electrodes.

[0005] Some examples include at least one of: accessing and computing theAttorney Docket No. Z20886WO-01information from a non-invasive blood pressure (NIBP) sensor. In some examples, the accessed information comprises at least one of: systolic blood pressure, diastolic blood pressure, and mean arterial pressure (MAP). In some examples, the computed information comprises mean arterial pressure (MAP). Some examples comprise at least one of: accessing and computing the information from the received signals from an invasive blood pressure (IBP) sensor. In some examples, the accessed information comprises at least one of: systolic blood pressure, diastolic blood pressure, and mean arterial pressure (MAP). In some examples, the computed information comprises at least one of: mean arterial pressure (MAP), pulse pressure variation (PPV), respiratory rate (RR), and pulse rate (PR). Some examples comprise at least one of: accessing and computing the information from the received signals from a capnograph. In some examples, the accessed information comprises end tidal carbon dioxide (EtCO2). In some examples, the computed information comprises a capnogram waveform. Some examples comprise at least one of: accessing and computing the information from the received signals from a pulse oximeter.

[0006] In some examples, the accessed information comprises at least one of: oxygen saturation (SpO2), and a photoplethysmography (PPG) waveform. In some examples, the computed information comprises at least one of: a photoplethysmography (PPG) waveform, pulse rate (PR), pulse pressure variation (PPV), a hypovolemia compensation measurement, and respiratory rate (RR). Some examples comprise at least one of: accessing and computing the information from the received signals from a sensor that senses flow rate. In some examples, the accessed information comprises respiratory rate (RR). In some examples, the computed information comprises at least one of: inspiratory' volume and expiratory' volume. Some examples comprise at least one of: accessing and computing the information from the received signals from a sensor that senses pressure. In some examples, the computed information comprises peak inspiratory pressure (PIP). Some examples comprise at least one of: accessing and computing the information from the received signals from a temperature sensor.

[0007] In some examples, the accessed information comprises temperature. Some examples comprise at least one of: accessing and computing the information from the received signals from one or more electrodes. In some examples, the accessed information comprises at least one of: an ECG waveform and heart rate (HR). In some examples, the computed information comprises at least one of: an ECG waveform, heart rate (HR), respiratory rate (RR), heart rate variability (HRV), and amplitude spectrum area (AMSA). In some examples, computing the information based in part on the received signals comprisesAttorney Docket No. Z20886WO-01computing the information based on information obtained using the received signals. In some examples, accessing the information comprises use of the monitoring director in applying at least one communication protocol in associating at least a portion of the received signals with the information. In some examples, computing the information comprises use of the monitoring director in applying software stored in the at least one memory to obtain the information. In some examples, computing the information comprises use of the monitoring director in applying at least one software based library stored in the at least one memory to obtain the information using information accessed by the monitoring director.

[0008] In some examples, the at least one software library is loaded into the at least one memory from, and upon connection of, a physiological sensor of the plurality' of physiological sensors to a port of the plurality of dynamically configurable ports. In some examples, computing the information comprises use of the monitoring director in applying the software stored in the at least one memory' to obtain the information using information accessed by the monitoring director, and comprises use of the received signals. In some examples, computing the information comprises use of the monitoring director in applying the software stored in the at least one memory to obtain the information using information accessed by the monitoring director, without use of the received signals. In some examples, displaying, on the monitoring device display, the arrangement of display units comprises use of the monitoring director in applying software stored in the at least one memory.

[0009] In some examples, the plurality of dynamically configurable ports comprises at least one of: a CAN FD port, a data interface (DI) port, a sensor agnostic data interface (DI) port, a serial port, a smart port, a USB port, a micro-USB port, a USB-C port. In some examples, the plurality of dynamically configurable ports is made of up data interface (DI) ports. In some examples, the plurality of dynamically configurable ports comprising a non-invasive blood pressure (NIBP) port. In some examples, selection of the plurality of physiological sensors permits minimization of total size and weight of the medical monitoring device and connected physiological sensors. Some examples comprise anon-removable battery. In some examples, the monitoring device display permits touch-based selection and actuation.

[0010] Some examples comprise a physical dial allowing user selection and actuation on the medical monitoring device. In some examples, a volume of the medical monitoring device is no greater than 1,200 cubic centimeters. In some examples, a volume of the medical monitoring device is no greater than 1,000 cubic centimeters. In some examples, a volume of the medical monitoring device is no greater than 820 cubic centimeters. In some examples, aAttorney Docket No. Z20886WO-01volume of the medical monitoring device is no greater than 2 kilograms. In some examples, a volume of the medical monitoring device is no greater than 1.8 kilograms. In some examples, a volume of the medical monitoring device is no greater than 1.6 kilograms.

[0011] In some examples, the plurality of dynamically configurable ports is made of 9-12 ports. In some examples, the plurality' of dynamically configurable ports is made of 6-8 ports. In some examples, the plurality of dynamically configurable ports is made of 2-5 ports. In some examples, the medical monitoring device is configured to be powered by battery or connect to and powered by an AC power source. In some examples, the medical monitoring device is configured to be powered by the AC power source using a USB-C port of the medical monitoring device.

[0012] Some examples comprise a plurality of illuminable indicators, comprising an illuminable indicator associated with each of at least some of the plurality of dynamically configurable ports, each of the illuminable indicators of the plurality of illuminable indicators configured to be illuminated when a phy siological sensor is connected to the port associated with the illuminable indicator and configured to be non-illuminated when no physiological sensor is connected to the port associated with the illuminable indicator.

[0013] In some examples, each of the illuminable indicators of the plurality of illuminable indicators is configured to flash at least upon at least one of: connection and disconnection of the physiological sensor to the port. In some examples, each of the illuminable indicators of the plurality of illuminable indicators comprises at least one of: a light-emitting diode (LED) display, an active-matrix organic light-emitting diode (AMOLED) display, and a organic light-emitting diode (OLED) display.

[0014] Some examples comprise at least one micro-controller. In some examples, each of the plurality of user configurable ports is further configured to allow connection of a connectable device other than a physiological sensor. In some examples, the connectable device comprises at least one of: a medical monitoring device, a ventilator, a defibrillator, a public access automated external defibrillator, a patient monitor, a critical care monitor (CCM) and an infusion pump device. In some examples, the connectable device comprises a display device that does not include a processor. In some examples, the display device that does not comprise a processor comprises at least one of a display screen and a projector. In some examples, the connectable device comprises a second medical monitoring device, and wherein the arrangement of display units comprises at least one display unit associated with a physiological sensor of the plurality of physiological sensors connected to the medical monitoring device and at least one display unit associated with a physiological sensorAttorney Docket No. Z20886WO-01connected to the second medical monitoring device.

[0015] One example provides a medical monitoring device for monitoring of a patient during treatment of the patient, comprising: a monitoring device display; a plurality of dynamically configurable ports, each configured to allow connection of any of a plurality of connectable physiological sensors, and each configured to allow connection of a physiological sensor of a plurality of physiological sensors connected to the medical monitoring device for monitoring of the patient, the medical monitoring device configured such that each of the plurality of physiological sensors is selectable by a user of the medical monitoring device at least in part by connection, to some or all of the plurality of dynamically configurable ports, of each of the plurality of physiological sensors; at least one processor and at least one memory, the at least one memory comprising a monitoring director configured to be executable by the at least one processor in: receiving signals from each of the plurality of physiological sensors, processing the received signals to obtain, for each of the plurality of physiological sensors, clinically presentable physiological information comprising a specific physiological parameter and a magnitude for the specific physiological parameter, displaying, on the monitoring device display, an arrangement of display units, each occupying a portion of an area of the monitoring device display, each configured to be associated with a specific physiological sensor of the plurality of physiological sensors, and each configured to display the information associated with the specific physiological sensor, and upon actuation relating to a first display unit of the arrangement of display units, cause display, on the monitoring device display, of a first enhanced display associated with the first display unit, the first enhanced display replacing at least some of the display units of the arrangement of display units, and the first enhanced display displaying additional information associated with the specific physiological parameter associated with the first display unit, the additional information being in addition to the information displayed by the first display unit, and upon actuation relating to the first enhanced display, cause display, on a display of a computing device communicatively connected with the medical monitoring device, of a first augmented display displaying further information associated with the specific physiological parameter associated with the first display unit.

[0016] Some examples are configured such that the plurality of physiological sensors is identified based on connection by a user of each of the physiological sensors of the plurality of physiological sensors to some or all of the plurality of dynamically configurable ports, wherein the plurality of physiological sensors is made up of physiological sensors connected to the medical monitoring device. Some examples are configured such thatAttorney Docket No. Z20886WO-01modification of the plurality of physiological sensors for monitoring of the patient can be accomplished by: disconnection of a first physiological sensor of the plurality to remove the first physiological sensor from the plurality, or connection of an additional physiological sensor to add the additional physiological sensor to the plurality.

[0017] In some examples, modification of the plurality of phy siological sensors allows customization based on a currently applied level of clinical care to the patient during a course of monitoring and treatment of the patient. In some examples, modification of the plurality of physiological sensors permits customization based on a level of expertise or training of a user of the medical monitoring device. In some examples, modification of the plurality of physiological sensors permits customization based on environmental conditions. In some examples, the monitoring device display is configured such that the first enhanced display replaces the arrangement of display units. In some examples, at least one of the display units is customizable to display information associated with more than one connected sensing device. In some examples, at least one of the display units is customizable to display¬ information associated with a selected physiological parameter, the selected physiological parameter being selectable from among multiple physiological parameters available for display by the at least one of the display units.

[0018] In some examples, at least one of the display units is customizable to display information associated with at least two selected physiological parameters. In some examples, at least one of the display units is customizable to display information associated with at least tw o physiological sensors. In some examples, the arrangement of display units is configured to be scrollable by a user. In some examples, the augmented display is configured to be scrollable by a user. In some examples, the arrangement of display units comprises a grid of display units. In some examples, the grid of display units comprises a grid of tiles. In some examples, each of the display units automatically displays the information associated wdth the specific physiological sensor of the plurality of physiological sensors upon attachment of the specific physiological sensor to the medical monitoring device. In some examples, at least one of the display units displays a trend arrow indicating a trend associated with a physiological parameter associated with the specific physiological sensor associated with the at least one of the display units.

[0019] In some examples, each of the display units has a rectangular shape. In some examples, the actuation relating to the first display unit is touch-based. In some examples, each of the display units displays at least one of: an alarm threshold, an early warning score (EWS) and a sensor related alarm. In some examples, the arrangement of display units isAttorney Docket No. Z20886WO-01customizable by a user of the medical monitoring device, and wherein customization of the arrangement of display units comprises selection of locations on the monitoring device display of display units of the arrangement of display units. In some examples, the first enhanced display comprises at least one trend plot associated with the specific physiological parameter associated with the first display unit. In some examples, the first enhanced display is customizable by a user of the medical monitoring device, and wherein customization of the first enhanced display comprises selection of at least a portion of the additional information associated with the specific physiological parameter associated with the first display unit. In some examples, the first augmented display is customizable by a user of the medical monitoring device, and wherein customization of the first augmented display comprises selection of at least a portion of the further information associated with the specific physiological parameter associated with the first display unit.

[0020] In some examples, the further information displayed on the computing device is in addition to the information displayed by the first display unit and in addition to the addition to the additional information displayed by the first enhanced display. Some examples are configured to store chronologically ordered information relating to the monitoring of the patient. In some examples, the first augmented display comprises at least one displayed waveform associated with the specific physiological parameter. In some examples, the first augmented display comprises early warning score (EWS) information. In some examples, the early warning score (EWS) information comprises at least one of: Los Angeles Motor Scale (LAMS) information, Modified Early Warning Score (MEWS) information, sequential organ failure (SOFA) information, and quick sequential organ failure assessment (qSOFA) information, Glasgow coma scale (GCS) information, and shock decision guidance score information. In some examples, the first augmented display comprises clinical decision support information. In some examples, the first augmented display comprises electrode placement guidance. In some examples, the computing device comprises at least one of: a portable computing device, a patient monitoring device and a medical device. In some examples, the computing device comprises a tablet. In some examples, the computing device comprises at least one of: a patient monitoring device, a ventilator, a defibrillator, a public access automated external defibrillator, a patient monitor, a critical care monitor (CCM) and an infusion pump device.

[0021] In some examples, the plurality of connectable physiological sensors comprises physiological sensors for enabling measurement of non-invasive blood pressure (NIBP), systolic blood pressure, diastolic blood pressure, mean arterial pressure (MAP),Attorney Docket No. Z20886WO-01invasive blood pressure (IBP), pulse rate (PR), pulse pressure variation (PPV), respiratory- rate (RR), end-tidal carbon dioxide (EtCO2), capnogram waveform, oxygen saturation (SpO2), photoplethysmography (PPG) waveform, a hypovolemia compensation measurement, inspiratory volume (Vi), expiratory volume (Ve), peak inspiratory pressure (PIP), temperature, heart rate (HR), ECG waveform, heart rate variability (HRV), and amplitude spectrum area (AMSA). In some examples, the plurality of connectable physiological sensors comprises a non-invasive blood pressure (NIBP) sensor, an invasive blood pressure (IBP) sensor, a capnograph, a pulse oximeter, a sensor that senses flow rate, a sensor that senses pressure, a temperature sensor, and one or more electrodes. Some examples are configured such that the computing device is communicatively connectable by wired or wireless connection. In some examples, each of the physiological parameters and the magnitude of each of the physiological parameters are updated at a frequency selected by a user of the medical monitoring device.BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Various aspects of embodiments of the present disclosure are discussed below with reference to the accompanying figures, which are not intended to be drawn to scale. The figures are included for illustrative purposes and a further understanding of the various aspects and examples. The figures are incorporated in and constitute a part of this specification, but are not intended to limit the scope of the disclosure. In the figures, identical or nearly identical components that are illustrated in various figures may be represented by like numerals. For purposes of clarity, not every- component may be labeled in every figure.

[0023] FIG. 1 illustrates an example emergency care environment including a customizable patient monitoring device with connected physiological parameter sensors, and a portable computing device, used in monitoring a patient.

[0024] FIG. 2 illustrates an example customizable patient monitoring device.

[0025] FIG. 3 illustrates an example customizable patient monitoring device, including a monitoring device display, multiple sensor ports and multiple connectable physiological parameter sensors.

[0026] FIG. 4A illustrates an example system including a customizable patient monitoring device including a monitoring device displaying an arrangement of display items, and a later monitoring device including an enhanced display, as well as a portable computing device including an augmented display.

[0027] FIG. 4B illustrates an example display of a computing deviceAttorney Docket No. Z20886WO-01communicatively coupled with a customizable patient monitoring device, including display of an ECG waveform, a non-invasive blood pressure (NIBP) waveform, and an oxygen saturation (SpO2) waveform.

[0028] FIG. 5 illustrates example trend and waveform plots that may be displayed on a customizable patient monitoring device or connected device.

[0029] FIGs. 6 and 7 illustrate example displays on a customizable patient monitoring device, including addition of a tile display associated with a physiological parameter.

[0030] FIG. 8 illustrates an example displayed grid of tiles of a customizable patient monitoring device, that may integrated based on information collected from sensors of more than one connected customizable patient monitoring device.

[0031] FIG. 9 illustrates an example displays, including grids of tiles, of a customizable patient monitoring device, in which a tile is updated by a user to display a different physiological parameter of several physiological parameters that may be sensed from a single sensing device.

[0032] FIG. 10 illustrates an example grid of tiles including trend arrows indicating trends associated with patient physiological parameters.

[0033] FIG. 11 illustrates an example of a tile that may be customized to display a selected physiological parameter display of multiple such displays.

[0034] FIG. 12 illustrates an example display on a customizable patient monitoring device, including a set of early warning scores (EWSs).

[0035] FIG. 13 is a flow diagram illustrating a method for providing a display of an arrangement of display items, and for providing an enhanced display, on a customizable patient monitoring device, as well as for providing an augmented display on a connected computing device.

[0036] FIG. 14 is a flow diagram illustrating a method for obtaining and displaying physiological parameter information that may be implemented by a software or code-based monitoring director of a customizable patient monitoring device, which may include accessing and / or computing the physiological parameter information.

[0037] FIG. 15 is a flow diagram illustrating a method for obtaining and displaying information on device(s) of a system including a customizable patient monitoring device, including accessed physiological information and information computed using a waveform computation library'.

[0038] FIG. 16 is a flow diagram illustrating an example of a method for accessing and computing physiological information on a system including a customizable patientAttorney Docket No. Z20886WO-01monitoring device, including use of electrode signals and one or more software libraries to compute secondary’ information.

[0039] FIG. 17 is a flow diagram illustrating an example of a method for accessing and computing physiological information on a system including a customizable patient monitoring device, including use pulse oximeter signals and software libraries to compute secondary information.

[0040] FIG. 18 is a flow diagram illustrating an example of a method for accessing and computing physiological information on a system including a customizable patient monitoring device, including use airway flow and pressure sensor signals and computation of secondary' infomiation.

[0041] FIG. 19 is an example of data transfer cable compatible with a sensor-agnostic data interface port for transferring sensor data to a device such as a customizable patient monitoring device or other device.

[0042] FIG. 20 is a schematic diagram illustrating components of a customizable patient monitoring device.

[0043] FIG. 21 is a block diagram illustrating example components of various devices that may be used in embodiments described herein.DETAILED DESCRIPTION

[0044] Some embodiments described herein provide devices, systems and methods for use in patient monitoring, such as for use in emergency, pre-hospital, or hospital care of a patient. For example, the device (and / or one or more other devices in a system of devices) may be portable and customizable, such as with regard to physiological sensing aspects and / or with regard to display aspects, or in other ways. In some embodiments, a customizable patient monitoring device is provided, which may be communicatively connected (e.g., via wireless or wired connection) to one or more other devices, such as accessories including sensing devices. For example, the customizable patient monitoring device may be connected with one or more computing devices, such as a portable computing device, e.g., a tablet, smartphone, headwom or smartglasses device. Additionally or alternatively, the customizable patient monitoring device may’ be connectable to one or more medical and / or therapeutic devices or portable therapeutic devices, such as a ventilator, defibrillator and / or another patient monitoring device.

[0045] In some embodiments, the customizable patient monitoring device may include multiple ports for potential connection, such as wired or wireless connection, of anyAttorney Docket No. Z20886WO-01of a variety of physiological sensors, such as physiological parameter sensors (which may, in various embodiments, include, e.g., any device or system that senses one or more physiological parameters or conditions). In various embodiments and / or during various uses at various times, physiological parameter sensors may be attached to one, some or all of the ports, which may leave none, one or several without an attached physiological parameter sensor. Each of the physiological parameter sensors may be capable of detecting one, or, in some cases, several different physiological parameters. For sensors that are capable of detecting multiple physiological parameters, a user may be able to select one or more physiological parameters that the sensor detects, and / or may be able to select which one or more of the physiological parameters are displayed, for example, on the customizable patient monitoring device and / or elsewhere.

[0046] In some embodiments, however, one or more of the ports may be configured for connection of one or more accessories other than physiological parameters sensors This may include other sensing devices, computing devices, or monitoring devices, for example. As described herein, such other connected devices may include one or more other customizable patient monitonng devices.

[0047] In some embodiments, some or all of the ports, for connection of sensors, may be dynamically configurable ports. For example, each of the ports may include a configuration and / or hardware, and the customizable patient monitoring device may include hardware and / or software, to enable each port to automatically and immediately detect and authenticate a sensor and / or type of sensor, or any of various sensors and sensor types, immediately upon connection of the sensor to the customizable patient monitoring device by a care provider. Furthermore, the customizable patient monitoring device may include software to allow the obtaining of clinically presentable information, such as, e.g., clinically relevant information associated with the patient being treated, which may include physiological parameter information. The foregoing may include, for example, algorithmically recognizing and identifying the clinically presentable physiological information from the received signals.

[0048] As described further herein, use of dynamically configurable ports can provide many advantages, including for pre-hospital (or hospital), field and military use. For example, use of dynamically configurable ports may allow a care provider to simply connect any of various sensors to any of the ports and immediately have the sensor be detected and useable in monitoring of the patient. For example, in some embodiments, immediately following connection of the sensor to a port, the sensor may be detected, recognized and useable inAttorney Docket No. Z20886WO-01patient monitoring, and the display of the customizable patient monitoring device (and potentially one or more other connected devices) may be immediately updated accordingly. For example, a grid of tiles display on the customizable patient monitoring device may be immediately updated such that an appropriate tile displays a physiological parameter and its value. It is noted that, herein, in some embodiments, displaying a parameter may include displaying the identity of the parameter, e.g., SpO2, and a magnitude of the parameter, e.g., 96%).

[0049] The customizable patient monitoring device may be configured such that all (or, in other embodiments, some) of the physiological parameter sensors are selectable by a user. For example, in some embodiments, the user may select the physiological parameter sensors simply by physically connecting the desired physiological parameter sensors to the customizable patient monitoring device, or in other or additional ways, such as wireless connection, or connection that may include or require interaction or customization via a display or graphical user interface (GUI). For example, this may allow the user much or complete flexibility and customizability with regard to physiological parameter sensors, in that the user can connect exactly those physiological parameter sensors (associated with specific physiological parameter sensing) that are needed or that the user perceives to be needed, e.g., for a particular environment, clinical conditions, level or stage of care, patient, or care provider expertise, potentially among other factors.

[0050] Additionally, during care of a patient, a care provider may be able to quickly remove a connected sensor from a specific port and replace it with a different physiological parameter sensor, as needed or desired during the course of care. For example, an emergency care provider may only need to periodically review particular patient physiological parameters and their magnitudes during patient care. As such, using just one port, at a given time, the care provider may elect to exchange or swap one connected physiological parameter (e.g., a temperature sensor to measure the patient’s current temperature) for another (e.g., a capnography sensor to measure the patient’s current EtCO2), during patient care, once or multiple times. Additionally, use of dynamically configurable ports may provide an advantage in that, in case one port becomes compromised or unusable for any reason, e.g., becomes faulty, dirty or blocked, then a user can simply use another port for connection of a sensor. This advantage is not available with dedicated ports (e.g., a port that is configured for connection of only one type of sensor).

[0051] Furthermore, in some cases, especially in field or military use, one or more ports may potentially become, for example, functionally compromised or unusable due toAttorney Docket No. Z20886WO-01debris accumulation, damage during field use or transport, or other reasons. In such cases, for example, a user may have the option to simply use or switch to available port(s) and avoid or change from compromised or unusable port(s).

[0052] The above described flexibility’ with regard to connected physiological parameter sensors may in turn may allow or enhance minimization of the total size, weight and / or complexity (which may include the complexity’ of display related features, as described herein) of the customizable patient monitoring device along with the connected physiological parameter sensors. For example, in some embodiments, few, one or no non-omittable or non-disconnectable and reconnectable sensors may be included, and only needed or desired physiological parameter sensors may be selected to be included. In some embodiments, the more built-in or non-omittable physiological parameter sensors included, the more these may add to the size, weight and complexity of the device. This includes cases in which monitoring of one or more of the associated physiological parameters may be unnecessary’ for a specific clinical situation or at a specific time.

[0053] Additionally, in some embodiments, a customizable patient monitoring device may include other features supporting minimization of size, weight, and / or complexity, such as an included rechargeable battery, which may reduce necessary removeable components of the customizable patient monitoring device. For example, in various embodiments, the volume of the customizable patient monitoring device may be, e.g.. no greater than, in cubic cm, 1,200, 1.000, 820, 700, 600. 500, 400 or less. In various embodiments, the weight of the customizable patient monitoring device may be, e g., in kg, no greater than 5, 4, 3, 2, 1.8, 1.6, 1.4, 1.2, 1.0, 0.8 or 0.6. In various embodiments, the number of sensor ports of the customizable patient monitoring device may be, e g., 1, 2-5, 6-8, 9-12, 12-15, 18-25, or greater than 25. In some embodiments, a customizable patient monitoring device may also enabled to be plugged in to a power source, such as an AC power source (e.g., via connection with a port such as aUSB-C port, or universal port, digital communications port, or other port), which may, when plugged in, avoid need to discharge the battery during use. In some embodiments, the port used for connection to a power source may also or alternatively be used for data communication or transmission.

[0054] In some embodiments, various devices, including accessories, such as may be part of a system including a customizable patient monitoring device, may be connectable either by wire (e.g., by use of ports) or wirelessly, e g., using the Internet and / or one or more wireless networks such as one or more local area networks (LANs) or wide area networks (WANS), public networks, private networks, etc. In some situations, one or more wirelessAttorney Docket No. Z20886WO-01networks and / or wireless communications may be required to be limited, unused or disabled, such as temporarily, for example, in a military context when such communications may create risk, e.g., of discovery or interception. Some embodiments provide a wired connection capability or option for sensors or other accessories for a customizable patient monitoring device or other devices, and / or for communications between devices in a system of devices or for accessories for such devices, and may also provide an ability (e.g., via a GUI) to disable or enable wireless communications, or to toggle between the two. Another situation in which wired, in addition to wireless, capability and convenient associated user interfaces may be advantageous include mass casualty events, in which wireless networks may be overburdened and unavailable, or intentionally turned off or disabled, such as by local authorities or other controlling or administering entities. Still another situation may include locations or situations in which wireless networks are unreachable or reception is poor or absent, such as very rural locations, underground parking garages or other underground environments, or inbuilding or other city or urban environments w here reception my not reach or may be limited or intermittent, for example.

[0055] Still further, as described herein, in some embodiments, a monitoring device display of a customizable patient monitoring device is provided that is customizable by a user, and / or that may use, for example, a grid-based display of tiles relating to connected physiological parameter sensors, which may provide advantages relating to simplicity, practicality, ease and speed of use. Additionally, as described herein, in some embodiments, a care provider / user may be easily and quickly able to obtain an enhanced display on the customizable patient monitoring device, and / or an augmented display on a connected device, relating to a specific physiological parameter for which the care provider requires additional information to support the evolving, specific, current patient monitoring and care situation.

[0056] Furthermore, in some embodiments, a tile, of a grid of tiles, may be customizable by a user to display information relating to a single physiological parameter obtained based on signals from a single connected physiological parameter sensor. However, in some embodiments, a tile may be customizable by a user to display (e.g., at a given time or during a specific time period) information associated with one of several physiological parameters, where information about each of the several physiological parameters may be obtained from a single connected physiological sensor. Furthermore, in some embodiments, a tile may be customizable by a user to display infonnation from each of multiple connected physiological parameter sensors, such as may relate to patient physiology (e.g.. one or more physiological parameters). However, in some embodiments, when a physiological parameterAttorney Docket No. Z20886WO-01sensor is connected, a tile automatically and by default populates with and displays appropriate or previously customized physiological parameter information. However, this default display may then be modified by a user to customize the display.

[0057] In various clinical situations, patient monitoring needs may change, such as spontaneously / in real time, as the patient care evolves and changes. In some embodiments, a customizable patient monitoring device allows connected physiological sensors to be removed (e.g., simply by being disconnected) or added (e.g., simply by being connected), allowing customization and modification of the set of connected physiological parameter sensors quickly / in real time (e.g.,, within seconds, such as within 1, 2, 3, 4, 5, 15, 30 or 45 or more seconds, or within 1, 2 or more minutes, for example), as the clinical situation and monitoring needs may change or evolve over time during care of the patient.

[0058] As an example, in a military or combat environment related situation, e.g., following a combat injury, patient monitoring needs may evolve over time during care, such as with a changing environment, changing patient condition, changing levels or stages of care, and potentially even changing care provider(s), among other factors. For example, initially, immediately following a combat injury, a relatively medically unskilled service member may provide emergency care. After some time, as care proceeds, a relatively more skilled care provider may arrive and join or replace the initial care provider, such as a combat medic (or paramedic). The combat medic may, for example, have additional accessories, such as additional physiological parameter sensors, which may support desired clinical patient monitoring, and which may be added in real time (e.g., within seconds) by the combat medic, potentially simply by connection to the customizable patient monitoring device (and, potentially, the combat medic may remove currently unneeded physiological parameter sensors, or may exchange / swap an unneeded physiological parameter sensor for a currently needed one).

[0059] Furthermore, for example, an initial medic may lack the expertise to operate or fully understand the functioning of a physiological parameter sensor, which expertise a more advanced clinician may have. Additionally, in certain environments or situations, at certain times, it may not be possible or feasible to use some physiological parameter sensors.Monitoring of invasive blood pressure, for example, may require introduction of a catheter, which may not be feasible in some environments or situations, and requires substantial clinician expertise. For example, an initial medic may start treatment of a patient using only non-invasive blood pressure measurement, and additional physiological parameter sensors may be connected and added (and / or removed) over time as care progresses and / or careAttorney Docket No. Z20886WO-01provider(s) are changed or added.

[0060] Also, the patient’s condition may improve or decline over this progression and over time periods. Furthermore, eventually, the environment may change to include a transport environment, and potentially in-hospital care. At each or some of these changes in and vary ing circumstances (potentially among others), patient monitoring requirements, including needed physiological parameter sensing and sensor requirements, may change. In some embodiments, the initial configuration of the customizable patient monitoring device and connected physiological parameter sensors may be customized by the care provider, and real time modifications may be made as circumstances and needs change. For example, at any time or stage, a care provider may disconnect one or more physiological parameters sensors and / or connect one or more others, thus selecting and customizing the set of connected physiological parameters sensors and sensed physiological parameters, and thereby customizing the configuration (and minimizing the size, weight, and / or complexity) of the customizable patient monitoring device and set of connected physiological parameter sensors, and potentially simplifying or helping simplify associated display(s) and displayed information.

[0061] In some embodiments, features, such as user customization features, of a customizable patient monitoring device, may include providing the user (e.g., via one or more GUIs) with the ability to set (including change, modify or update to) an update rate for each monitored and / or displayed physiological parameter. This may provide the advantage of allowing the user to choose an update rate for each parameter that is optimized wi th regard to necessary' or optimally high speed of updating (e.g., considering situation-specific clinical needs) balanced against minimizing rate of battery' discharge or drain (in the particular situation), which may be higher for higher update rates. For example, a user may decide that an optimal balance is struck by setting heart rate (HR) to update every minute (or more or less), setting SpO2 to update every' 5 minutes (or more or less), and setting EtCO2 to update every 10 minutes (or more or less), which the user may decide provides an optimal balance regarding allowing or maximizing frequent updated monitoring of key parameters while also minimizing battery load or drain rate, thereby maximining the amount of time before the battery is drained fully or otherwise to an extent that it can no longer pow er or fully pow er the device.

[0062] In various embodiments and examples, many factors may be taken into account in such balancing and decision-making These factors may include, for example, the specific patient (e.g., characteristics, physical condition, injury or disease and severityAttorney Docket No. Z20886WO-01thereof, improving or worsening condition, how quickly specific parameters are likely to change, how critical each parameter is), the specific situation (e.g., pre-hospital or hospital, field, military, mass casualty, transport such as land, sea or air transport, and the specifics thereof), the expertise level of the care provider, practice and preferences of the care provider in monitoring of the patient and specific parameters, and other aspects of the environment or situation (e.g., current battery charge and anticipated time until discharge based in part on parameter update settings, how long the battery is expected to be needed for), clinician situation, treatment plan, likely treatment or patient condition trajectory, and other factors. For example, if a care provider expects a specific parameter to be critical to care, expects to need or be able to check the specific parameter more frequently, and expects that battery charge is not a large concern, these factors may favor setting a higher update rate for the parameter. However, if the care provides expects a specific parameter to be less critical to care, expects to need or be able to check the parameter less frequently, and expects that battery life is a large concern, these factors may favor setting a lower update rate for the parameter.

[0063] In some embodiments, a customizable patient monitoring device may include various features, such as hardware or software related features, that increase practicality, ease, speed and / or simplicity' as relates to connection and use of a wide variety7of physiological parameter sensors, such as may include current or future physiological parameter sensors. For example, one or more types of ports or digital communication ports, such as standardized and / or universal ports, may be used, e.g., CAN FD ports such as may include data interface (DI) ports, such as sensor agnostic data interface (DI) ports and / or serial ports such as may include smart ports (also available from ZOLL Medical Corporation). Furthermore, in various embodiments, various types of physical ports and connection ty pes may be used, such as, e.g., magnetic ports or connectors for use in connection of physiological sensors. Additionally, use of the customizable display ty pes as described herein, including, for example, grids of tiles, enhanced displays and augmented displays, may provide advantages as relate to practicality, and ease and simplicity of use, such as in fast-moving and potentially chaotic emergency treatment environments and situations.

[0064] Additionally, software-based or code-based communication and data transmission protocols, such as standardized and / or universal protocols, may be used, that support interoperability and communication of the customizable patient monitoring device with a wide variety7of current or future physiological parameter sensors or other accessoriesAttorney Docket No. Z20886WO-01or devices. In some embodiments, some types of ports, e.g., CAN FD ports or sensor agnostic data interface (DI) ports, such as sensor-agnostic DI ports, may provide an advantage in that they may not require electrical isolation with a customizable patient monitoring device.Additionally, such ports, including DI ports, may include current and future implementations of such ports (e.g., with potential physical or electronic modifications). For example, DI ports, including sensor-agnostic DI ports with electrical isolation features, which may be used in embodiments herein, are described in U.S. Pat. No. 12,102,590, entitled, "MEDICAL DEVICE SYSTEM AND HARDWARE FOR SENSOR DATA ACQUISITION.” And assigned to ZOLL Medical Corp. Such included features and software may also avoid need for software updates to the customizable patient monitoring device to permit interoperability with various cunent or future physiological parameter sensors or other accessories or devices. Additionally, such features may support immediate compatibility with various communication protocols and standards, and may minimize associated regulatory requirements or burden. Examples of aspects of ports and / or physiological parameter sensors, and associated hardware and software for receiving signals and obtaining information or data therefrom, which may be used in embodiments of the customizable patient monitoring device, may be in accordance with aspects of such as described in U.S. Patent Number 12,102,590.

[0065] In some embodiments, a software-based or code-based monitoring director may be used, which may be stored in one or more memories of. and executed by one or more processors of, a customizable patient monitoring device. For example, the monitoring director may be used in facilitating communication and interoperability of the customizable patient monitoring device with any of various physiological sensors. The monitoring director may facilitate accessing (e.g.. recognizing) and displaying physiological parameter information from any of the various physiological parameter sensors. Such physiological parameter information may include a physiological parameter (or more than one) sensed by the physiological parameter sensor, e.g., SpO2 (oxygen saturation), as sensed by a pulse oximeter sensor (which may also be called an SpO2 sensor), as well as a measured magnitude (which may, e.g., include any value or indication relating to the measurement of the parameter, e.g., numerical values or ranges, or textual, symbolic or other indications, such as high or up arrow, medium or no arrow, or low or down arrow, etc.) relating to the sensed physiological parameter (e.g., the currently measured SpO2), potentially among other information, such as may be associated with the physiological parameter sensor or sensed physiological parameter (or parameters).Attorney Docket No. Z20886WO-01

[0066] For example, some physiological parameter sensors may transmit signals that identify the physiological information, such as clinically presentable physiological parameter information or data, e.g., the specific physiological parameter, such as SpO2, and currently measured magnitude thereof (e.g., currently measured SpO2 percentage), potentially among other information. However, some physiological parameter sensors may transmit signals that do not explicitly identify the physiological parameter data, e.g., the sensed physiological parameter and / or magnitude thereof (or other information), but may transmit signals that allow identification of the physiological parameter data by embodiments of a customizable patient monitoring device, such as may be accomplished or facilitated by use of the monitoring director. In some embodiments, the monitoring director may be used in determining which of these situations is the case, and in obtaining physiological parameter information (which may include data) from the received signals accordingly. For example, in some embodiments, the monitoring director may access or include software-based or codebased libraries (which may include resources such as code, classes, scripts, procedures, and configuration data, among other things) that facilitate accessing the physiological parameter information from the physiological sensors, and / or displaying the obtained physiological parameter data, e.g., on a display of the customizable patient monitoring device or a communicatively connected device, such as a portable computing device and / or therapeutic medical device.

[0067] For example, in some embodiments, a customizable patient monitoring device may process signals received from different detected connected sensors in different ways in order to access, or most efficiently or optimally access, clinically presentable physiological information, such as physiological parameter information, that is received from each of the sensors. Furthermore, software libraries may be used in further processing the accessed information, and / or the received signals or other information or signals, to obtain other information. For example, in some cases, such as depending on the connected sensor as detected by the customizable patient monitoring device, the processing may include using and executing software (e.g., one or more software libraries or other software) that may include algorithms or code to allow accessing the physiological parameter information. In some embodiments, libraries (or other software) may be pre-loaded into a memory of and executed by a processor of, the customizable patient monitoring device. Additionally or alternatively, in some embodiments, libraries (or other software) may be loaded upon connection of a specific accessory or sensor, such as from the accessory or sensor itself, another connected device or elsewhere. The one or more software libraries used may beAttorney Docket No. Z20886WO-01selected by the customizable patient monitoring device depending on the detected connected device, for example, and / or other factors as described herein.

[0068] In some embodiments, the monitoring director is executed to obtain clinically presentable physiological information such that, if clinically presentable physiological information is accessible from signals received by a connected physiological sensor, then the information is accessed from the received signals; however, if clinically presentable physiological information is not accessible from the received signals, then the information is computed based at least in part on the received signals.

[0069] Clinically presentable physiological information may include, for example, information that may be useful or relevant in medical monitoring of the patient and that may, in some examples, be associated with one or more physiological parameters relating to a patient. Physiological parameters may include, for example, information relating to the physiology of the patient, such as a specific physiological parameter and a magnitude thereof (e.g., EtCO2, SpO2), or other information such as, or relating to, trend plots, waveforms, or other information.

[0070] In some embodiments, in some situations, the monitoring director may use software to obtain clinically presentable physiological information from the received signals, such as information that is identified in the received signals. However, in some situations, alternatively or additionally, the monitoring director may use software, such as one or more libraries, to compute clinically presentable physiological information based at least in part on the received signals. For example, the monitoring director may select to access the information if it is accessible from the received signals. However, if the information is not accessible from the received signals, but is computable based at least in part on the received signals, then the monitoring director my select to compute the information. Computing the information based on the received signals may including computing the information with or without using the received signals.

[0071] Computing the information, such as clinically presentable physiological information, from the received information may be accomplished in different ways, as may be selected by the monitoring director, such as based on what is possible or most advantageous using available information, potentially from multiple sources and relating to multiple physiological parameters of the patient. Furthermore, in some instances, computing the information in different ways may be possible, such as using signals received from different sensors and / or using different obtained physiological parameters in computing the information. In such instances, the monitoring director may choose the method of computingAttorney Docket No. Z20886WO-01the information based on what is optimal or most advantageous, such as , e.g., what is computationally simpler or faster, or what provides the most accurate or certain information.

[0072] In some cases, computing the information based at least in part on the received signals may include performing a computation using only the received signals, but where the information is not accessible from the received signals, but must be obtained based on a computation using the received signals. In other examples, computing the information based at least in part on the received signals may include performing a computation using the received signals and other information, e.g., other received signals, such as from one or more other sensors, other physiological information, such as previously or currently accessed or computed other physiological information, or any other useful and available other information.

[0073] In other examples, computing the information, such as clinically presentable physiological information, based at least in part on the received signals may include performing a computation without using the received signals. In various examples, the foregoing may include using available information that was obtained (e.g., accessed or computed) using the received signals (by the monitoring director or otherwise), and / or that was obtained otherwise, but where the computation may not include use of the received signals.

[0074] In some embodiments, a customizable patient monitoring device may cause storage of, for example, historical, chronologically ordered / time stamped information, such as event markers, and associated information (e g. details of associated patients, patient monitoring diagnoses and treatment, and devices) such as in a memory of the customizable patient monitoring device, or in a memory of one or more other connected devices (e.g. physiological parameter sensors, a tablet, or a therapeutic device) or connected systems or platforms (e.g., a remote computing system or platform). The stored information may relate to any of various aspects of events and details associated with a customizable patient monitoring device or associated system (including hardware, software, or operational aspects), or connected devices, as well as information relating to events and details associated with operation of such devices, including with regard to patient monitoring, diagnosis and treatment, and events and details relating to associated events, such as conditions and manual treatments administered during patient care. For example, the stored information may include various information and details relating to events associated with the customizable patient monitoring device or connected devices. For example, the information may include summary information about courses of treatment administered to specified patients, and / or stagesAttorney Docket No. Z20886WO-01thereof, as well as events within these larger events. For example, the stored information may include chronologically ordered histories of connected and disconnected physiological parameters sensors, physiological parameters sensor measurements or other events (e.g., alarms); uses, selections / actuations, customizations and obtained displays of the customizable patient monitoring device, and potentially of connected devices; patient conditions; environmental or clinical conditions; diagnoses of, and treatments relating to patients, and / or other information.

[0075] In some embodiments, the customizable patient monitoring device (and / or connected device) may include GUI-based displays or physical controls to allow a user to access and / or display, and potentially search, mine, organize or otherwise manipulate, the stored historical information. For example, in some embodiments, a user may access and use stored information to review details of prior care, or prior stages of care, of a patient, which may be helpful in providing or optimizing ongoing care to the patient. Furthermore, in some embodiments, the stored information may be accessed and used separately from patient monitoring and care, such as to mine and utilize aggregated information across a range of patients and patient monitoring and care environments and situations. The aggregated or compiled information may be used, for example, to obtain statistics and / or a better understanding of patient monitoring and care, and progression and evolution of care of patients and patient conditions, and to improve or optimize aspects thereof as may be applied to future patients.

[0076] In some embodiments, a customizable patient monitoring device includes a monitoring device display, which may display, among other things, patient physiological parameter information and / or associated information. In some embodiments, information displayed on the patient monitoring device display may be used in, or to facilitate, patient care, including, for example, assessment, diagnosis and / or treatment of a patient. In some embodiments, a software-based or code-based monitoring director may be used in or to facilitate display of various information on the customizable patient monitoring device, and potentially other devices, such as one or more communicatively connected devices, such as a portable computing device. In various embodiments, various displays may be provided by the monitoring device display, such as displays including specific types or categories of information, as may include information that relates to monitored patient physiological parameters, and / or other information, for example. Additionally, in some embodiments, a customizable patient monitoring device may include other presentation features and aspects, such as audio and / or tactile presentation capability. In some embodiments, these otherAttorney Docket No. Z20886WO-01presentation aspects and features may be coordinated with displays (e.g., an alarm or alert may include a display aspect and associated alarm alert sound (e.g.. a loud beeping sound) and / or tactile aspects (e.g., vibration to alert a user).

[0077] For example, in some embodiments, an arrangement of display units may be displayed. Each display unit of the arrangement of display units may display physiological parameter information (potentially among other information) obtained from a specific connected physiological parameter sensor (e.g., a pulse oximetry sensor) such as may include a specific physiological parameter associated with the specific physiological parameter sensor (e.g., SpO2 of the patient) and a magnitude for the specific physiological parameter (e.g., a current SpO2 percentage of the patient).

[0078] In some embodiments, each of the display units may display additional information associated with the specific physiological parameter. For example, such additional information may include early warning scores (EWSs) (which may include modified early warning scores (MEWSs), which may, for example, be used in quickly assessing a degree of patient illness and / or patient's physiological state, such as by evaluating measured patient physiological parameters or other parameters or conditions, and may include assigning score(s), such as to identify patients at risk of clinical deterioration and requiring specific intervention. The additional information may also include alarm limits or thresholds, which may specify upper or lower bounds associated with the specific physiological parameter, beyond which an alarm may be triggered for the attention of a care provider, for example. The additional information may further include physiological parameter sensor related alarms, such as may alert the user when an issue or problem arises with a physiological parameter sensor, such as if it is not functioning properly, or is not measuring or calibrated properly or accurately.

[0079] In some embodiments, the EWS information may include one or more of: Los Angeles Motor Scale (LAMS) information, Modified Early Warning Score (MEWS) information, sequential organ failure (SOFA) information, quick sequential organ failure assessment (qSOFA) information, Glasgow coma scale (GCS) information, and shock decision guidance score information, for example.

[0080] In some embodiments, the arrangement of display units may be or include a grid-based display, such as may include columns and rows, and each display unit may be, for example, a rectangularly shaped area (whether or not square, or, in some embodiments, a different shape or area entirely) of the monitoring device display, which rectangularly shaped display units may be referred to herein as tiles. For example, the displayed grid of tiles mayAttorney Docket No. Z20886WO-01include a tile associated with each physiological parameter sensor connected to the customizable patient monitoring device (or, in some embodiments, for one. some or all of the connected physiological parameter sensors, more than one tile, or no tiles). Furthermore, the grid of tiles (or other arrangement of display units) may be customizable by the user. For example, in some embodiments, one or more GUIs or controls may be provided on the monitoring device display to allow the user to specify the specific locations, with the grid of tiles (or other arrangement of display units), for each of the displayed tiles, such as a column and row in the grid for each of the displayed tiles or location on the monitoring device display. Additionally, in some embodiments, one or more GUIs or controls may be provided to allow the user to format or specify particular values for information displayed by a tile.

[0081] Furthermore, in some embodiments, the user may be able to customize and specify aspects of the information displayed by the tile (or tiles) and / or the format or size or display details of the tile (or tile), or of aspects of the grid (or other arrangement of tiles, such as the format or size thereof, or other aspects relating to the information displayed in the grid of tiles or display thereof). In some embodiments, similar customization or adjustments may be made with regard to an enhanced display or an augmented display, whether on the customizable patient monitoring device or another device, and whether such customization or adjustment is made on controls or a display / GUI of the customizable patient monitoring device and / or one or more other devices or systems.

[0082] In some embodiments, the grid of tiles (or other arrangement of display units) may provide a relatively simple, quickly usable display of monitored patient physiological parameters, such as for the use of an emergency user / care provider (or non-emergency care or hospital care provider). Additionally, in some embodiments, the grid of tiles may include only tiles based on physiological parameter sensors, or sensed parameters associated with physiological parameter sensors, selected by the user, so that, for example, the grid of tiles is effectively customized such that only display of needed or useful physiological parameter information is provided, or such display is maximized, and unnecessary' physiological parameter information that may complicate the displayed information and reduce its immediate and effective usability by the emergency care provider is eliminated or minimized. Additionally, the grid of tiles may present the physiological parameter information in a simple, organized and easily immediately perceivable manner, further increasing immediate and effective usability, such as by the user / care provider. Still further, in some embodiments, the grid of tiles may provide an optimal use of the display area available on the customizable patient monitoring device, providing critical patient physiological parameter informationAttorney Docket No. Z20886WO-01needed in emergency care, where complication by added, unnecessary' information is eliminated or minimized. In some embodiments, if and when a care provider requires additional information, features may be included to accommodate such needs, such as the availability of an enhanced display on the monitoring device display of the customizable patient monitoring device, and / or the availability' of an augmented display on a communicatively connected device, as described herein.

[0083] In some embodiments, each tile (or other display unit) of the grid of tiles (or other arrangement of display units) may be selectable and actuatable, such as by being touched by a user, to cause display of an enhanced display on the monitoring device display of the customizable patient monitoring device. In some embodiments, a software-based or code-based monitoring director, of the customizable patient monitoring device, may be used in providing or facilitating the enhanced display. In some embodiments, the enhanced display may be larger in area than an individual tile, and may replace at least some of, or all of, the displayed tiles (or, in some embodiments, may not replace any tiles). The enhanced display may, for example, provide additional information relating to the specific physiological parameter associated with the actuated tile. For example, the enhanced display may provide, among other things, a chart or other graphic, such a trend chart based on a series of chronologically spaced data points representing the magnitude of the specific physiological parameter, or an associated derived parameter, over a recent or current period of time during patient care. The enhanced display may alternatively or additionally provide other information associated with the specific physiological parameter, such as textual, numerical or symbolic information. In some embodiments, an emergency care provider may use a selected touch-actuatable tile to easily, intuitively and immediately obtain more information about a specific monitored physiological parameter, as may be needed, for example, as patient condition and patient treatment develops and evolves during monitoring and treatment, including changing environments, stages or levels thereof, changing care providers, or other changing or changed conditions.

[0084] In some embodiments, an enhanced display (or, in some embodiments, e.g.. a grid of tiles or augmented display) may provide various other graphics and information. For example, other graphical or textual information, physiological parameter related waveforms (e.g., an ECG waveform) or trend plots, user guidance (e.g., regarding defibrillation electrode placement), advisories, protocols, scores, etc., may be displayed. Additionally, one or more GUIs may be provided to allow various user actions or settings changes relating to the customizable patient monitoring device or connected devices.Attorney Docket No. Z20886WO-01

[0085] For example, the user may be provided with one or more GUIs to allow setting, changing or editing of the position or display of individual tiles of a grid of tiles, such as to set or change high or low parameter alarm limits or the configuration of tiles in various displays. Furthermore, one or more GUIs may be provided to allow a user to scroll through options (e.g., specific physiological parameters) to choose one (or, in some embodiments, several) for display on a specific or selected tile of a grid of tiles, or to specify details of such displays (e.g., specific displayed information, the position of each element of displayed information, etc ). In some embodiments, if no user selection is made within a predetermined time limit, the display may return to a previous or default display. Additionally, for example, a user may be provided with one or more GUIs to allow change of the time, or timing increments, with which specific display elements are updated, such as numerical or textual information, waveforms or trend plots (e.g., in seconds, every less than 1, 5, 15, 30 or 60, or, in minutes, every 1, 5, 10, 15, 30, or 60).

[0086] Furthermore, in some embodiments, the user may be able to select a timing increment (e.g., in seconds, every less than 1, 5, 15, 30 or 60, or, in minutes, every 1. 5, 10, 15, 30, or 60) for computationally updating (e.g., computing) specific display elements, which may or may not be identical to a display timing increment. Both the display updating timing increment and the computational updating timing increment may affect battery discharge rate, and thus the amount of time that the battery continues to provide power (or sufficient power) to the customizable patient monitoring device, where shorter updating timing increments increase frequency of updating and thereby increase battery discharge rate and reduce the amount of time that the battery continues to provide power. In some embodiments, offering the user such options provides the advantage of allowing the user to make the selections based on an optimization, where shorter display and / or computationally updating increments (and therefore higher update frequencies) reduce the amount of time that the battery can provide power, and longer display and / or computational updating increments (And therefore lower update frequencies) increase the amount of time that the battery can provide power, for example.

[0087] In some instances, a specific physiological parameter may be, for example, computed based on information, such as waveforms, obtained from each of two or more specific connected accessories or sensors. In some embodiments, in such instances, a user may be provided with options relating to display of the specific parameter (e.g., via one or more GUIs). For example, the user may be provided with an option to choose between tiles associated with each of the specific connected sensors, for display of the specific parameter.Attorney Docket No. Z20886WO-01Furthermore, in some embodiments, for a display element, such as a tile of a grid of tiles, including in a situation in which multiple parameters are obtained from a single connected sensor, the user may be able to set or customize aspects of the display. For example, the user may be able to choose a setting for the tile such that it continuously displays a selected parameter (including its identity and value) from among several that might be displayed in association with the connected sensor. Alternatively, the user may be provided with the ability to choose a setting for the tile such that, over time, it automatically alternates or scrolls through display of each of several of the multiple parameters (including identity and value). Furthermore, the user may be able to choose the amount of time for which each parameter of the multiple parameters is displayed (including identity and value) before automatic alternating or scrolling to another of the multiple parameters. In various embodiments, the specified amount of time may apply to all of the multiple parameters, or may be selected for each parameter individually, e.g., so that more highly prioritized parameters are displayed for a greater amount of time, or based on other factors. Furthermore, the user may be able to customize various other aspects of content, formatting, colors, etc., as may apply to each of the multiple parameters or each individual parameter.

[0088] In some embodiments, the enhanced display may be actuatable, such as by a portion thereof being touched by a user, to cause display of an augmented display on one or more communicatively connected devices (and / or, in some embodiments, on the customizable patient monitoring device), such as one or more portable computing devices (e.g., a tablet) or one or more therapeutic medical devices, whether local or remote from the customizable patient monitoring device. Furthermore, in some embodiments, the augmented display may be provided on a display of a computing device or monitor of a remote computing platform. For example, in some embodiments, the user may touch (or otherwise select or actuate) any portion of the enhanced display, or, in other embodiments, one or more specific portions or areas of the enhanced display (as may, for example, be indicated on the enhanced display) to cause display of the augmented display on the communicatively connected device. The augmented display may include further information relating to the specific physiological parameter associated with the enhanced display and / or the actuated tile, the further information being in addition to the information displayed by the actuated tile and the enhanced display. For example, in some embodiments, the augmented display may include graphics (and / or, e.g., text, symbols, etc.), such as one or more waveforms associated with the specific physiological parameter, e.g., a photoplethysmography (PPG) waveform associated with measured SpO2 over a recent or current period of time during patient care\.Attorney Docket No. Z20886WO-01Furthermore, in some embodiments, the customizable patient monitoring device and / or one more other connected devices may include one or more controls and / or one or more GUIs to enable changing or toggling between various displays (e.g., a grid of tiles display, an enhanced display, and / or an augmented display).

[0089] In some embodiments, the augmented display may be larger in area and / or more complex, of higher resolution, and / or or sophisticated than the enhanced display on the customizable patient monitoring device. For example, in some embodiments, a care provider may use touch to actuate the enhanced display to intuitively and immediately obtain (or, in some embodiments, to cause to be provided to the computing device of another or additional care provider) further information, on a display of connected computing device (e.g., a tablet), about a specific monitored physiological parameter, beyond or different than information provided by the enhanced display, as may be needed as patient condition and patient treatment develops and evolves during monitoring and treatment, including changing environments, stages or levels thereof, changing care providers, or other changing or changed conditions.

[0090] FIG. 1 illustrates an example emergency care environment 100 including a customizable patient monitoring device 102, including a patient monitoring device display 108, with multiple connected physiological parameter sensors 112, 114 (although more than two may be included), and one or more computing devices, such as one or more portable computing devices 104, including a portable computing device display 150, communicatively connected to the customizable patient monitoring device 102, such as by wireless or wired connection. However, in some embodiments, the computing device, such as the portable computing device 104, may not be included. In some embodiments, one or more additional connected devices 106, such as one or more therapeutic devices or patient monitors, may also be included.

[0091] In various embodiments, one or more additional devices 104, 106 may or may not be included that are communicatively connected to the customizable patient monitoring device 102, such as by wireless or wired connection. The one or more additional devices 104, 106 may include, for example, among other things, a computing device, portable computing device, e g., a tablet, smartphone, headwom, smartglasses device, a monitor, patient monitor, a critical care monitor (CCM), a medical device, and / or a therapeutic device such as a defibrillator, automated external defibrillator (AED), ventilator or portable ventilator, infusion pump, or computing device or monitor of a remote computer, remote computing system or remote computing platform. One example of a portable ventilator that may be usedAttorney Docket No. Z20886WO-01in some embodiments is described in U.S. Patent Application Number 17 / 449,999, publication number US20220105288, entitled, “RESPIRATORY DISTRESS MANAGEMENT APPARATUS, SYSTEM AND METHOD. While not shown in FIG. 1, in some embodiments, the portable computing device 104 and / or the one or more other devices 106 may include one or more physiological parameter sensors that may be attached to the patient to receive physiological parameter associated signals from the patient.

[0092] Each of the one or more additional devices 104, 106 may (or, in some embodiments, may not) include a connected device display 150, 118. Each or some of the displays 150, 118 may, for example, be or include a touchscreen, and / or, in other embodiments, may include physical input features such as one or more buttons, dials, etc. The touchscreen(s) can receive input by touch from a user. For example, the user may touch the touchscreen or a portion thereof to make a selecting and / or to actuate the touchscreen or a portion thereof, such as to cause a new or additional display to be provided on the device including the touchscreen, and / or on one or more other device displays. The touchscreen may be or include, for example, a light emitting diode (LED) display, an active-matrix organic light-emitting diode (AMOLED) display, a organic light-emitting diode (OLED) display, or another type of display, and may, for example, be or include a capacitance or optical touchscreen, for example.

[0093] The multiple connected physiological parameter sensors 112, 114 may be attached to the patient to receive and transmit, to at least the customizable patient monitoring device 102, physiological parameter associated signals from the patient (e g., in addition to, if any, physiological parameter associated signals received by the customizable patient monitoring device 102 by one or more other devices of in the environment 100). As described herein, the customizable patient monitoring device 102 may include multiple ports, such as universal or standardized ports, such as may include sensor agnostic data interface (DI) ports and / or smart ports, for example, and associated hardware and software (which may include, for example, a software-based or code-based monitoring director, as described herein) to allow or facilitate communicative connection with any of a variety of physiological parameter sensors, such as may include current or future physiological parameter sensors.

[0094] Some example physiological parameter sensors that may be connected to the customizable patient monitoring device 102 may include sensors for sensing the following, among other things: non-invasive blood pressure (NIBP), invasive blood pressure (IBP), temperature, end-tidal carbon dioxide (EtCO2), oxygen saturation (SpO2), patient airway pressure, patient airway flow rate, electrocardiogram (ECG), respiratory rate, amplitudeAttorney Docket No. Z20886WO-01spectrum area (AMSA), pulse pressure variation (PPV), systolic pressure variation (SPY), total hemoglobin, carboxyhemoglobin (SpCO), pleth variability index (PVI). methemoglobin, expiratory volume, inspiratory volume, heart rate variability, ST elevation, and impedance. In some embodiments, the customizable patient monitoring device 102 may (or may not) have a dedicated non-invasive blood pressure (NIBP) port, and may or may include supporting pneumatics. In some embodiments, a customizable patient monitoring device may allow connection with, and may be capable of displaying (or accessing and displaying) physiological parameter related information from, many different types of physiological parameter sensors. These may include, among others, ECG sensors, electrodes, pulse oximeters, capnography sensors, invasive and non-invasive blood pressure sensors, airflow / gas flow sensors, pressure sensors, force sensors, magnetic sensors, thermistors, accelerometers, temperature sensors, humidity sensors, thermals sensors, thermal mass flow sensors, Accuvent sensors (Available from ZOLL medical Corporation) and RD rainbow™ sensors (available from Masimo Corporation, having a corporate office in Irvine, CA).

[0095] In some embodiments, a single sensor may be used in measurement of multiple physiological parameters. As some examples, which are not intending to be limiting: an ECG sensor may be used to measure heart rate (HR), respiratory rate (RR), heart rate variability (HRV), and amplitude spectrum area (AMSA); an Accuvent sensor can be used to measure tidal volume, inspiratory volume (Vi) and expiratory volume (Ve); a pulse oximeter can be used to measure oxygen saturation (SpO2), pulse rate (PR) and pulse pressure variation (PPV); a capnography sensor can be used to measure EtCO2 and RR; an invasive blood pressure sensor can be used to measure PR, RR, PPV and mean arterial pressure (MAP); and a flow sensor may be used to measure tidal volume, Vi and Ve, for example.

[0096] FIG. 2 illustrates an example customizable patient monitoring device 200. In the embodiment shown, the customizable patient monitoring device 200 includes a total of 9 ports (although, in various embodiments, various numbers of ports, of one or more types, may be included, such as less than 9 (e.g., 1, 2, 3, 4, 5, 6, 7 or 8), or more than 9 (e.g., 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 or more than 20). Furthermore, in some embodiments, for example, one or more of the ports may be used for connection of another customizable patient monitoring device, such as via wireless connection with, or wired connection to a port of, the other customizable patient monitoring device, or by wireless connection. This may allow for connection or chaining together of two or more such devices (e.g., one may connect to another, and the other may connect to yet another, etc., and / or each may connect to several others). The connected customizable patient monitoring devices may be used in an integratedAttorney Docket No. Z20886WO-01system of devices, including sensors connected to each of the customizable patient monitoring devices. This may allow for connection of more sensors, between the two customizable patient monitoring devices, than may be possible using only one such device. For example, in some embodiments, displays, such as grids of tile displays, enhanced displays or augmented displays, as described herein, may integrate or incorporate tiles that display physiological parameter information obtained from physiological parameter sensors of multiple customizable patient monitoring devices (and / or one or more other connected devices).

[0097] Specifically, in the embodiment depicted in FIG. 2, the customizable patient monitoring device 200 includes 8 dynamically configurable data interface (DI) ports 240, 242 and a non-invasive blood pressure (NIBP) port or module 210. The customizable patient monitoring device 200 also includes a rotary dial 206. In some embodiments, the rotary dial 206 (or another physical or GUI-based control, for example) is included as an alternative or back-up to touch-based (or other physical or GUI-based) control. For example, in some embodiments, the rotary dial 206 may be turned to select an aspect or feature for which a selection or actuation is to be made (as may be displayed on the monitoring device display of the customizable patient monitoring device 200), and may be pressed to make a selection or actuation. In the embodiment depicted, the customizable patient monitoring device 200 includes an LED indicator 208 associated with / closest to each of the ports 202, 204. In some embodiments, an LED indicator 208 is used to indicate whether a sensor is connected to the port closest to the LED indicator (e g., the LED indicator may be illuminated or flash when a sensor is connected to the port or non-illuminated when no sensor is connected to the port). Furthermore, in some embodiments, the LED indicators 208 (or other indicators) may be used to indicate one or more other conditions. For example, the LED indicators may be illuminated or flash to indicate changes in system or display configurations, physiological parameter related conditions such as trend changes, noise quality conditions, or alerts or alarms as may relate to the sensor connected to the port, among other things. In some embodiments, whether the indicator is constantly illuminated or flashing may provide a specific indication or alert (e.g., constantly illuminated or not illuminated if the sensor is connected and there are no problems or concerns relating to it, or flashing if the sensor is illuminated and there are one or more problems or concerns relating to it). Furthermore, in some embodiments, the LED indicators 208 may include color indicators capable of being illuminated in different colors, where each color may indicate different conditions, for example, a degree of urgency or concern of an alert, such as may relate to treatment of theAttorney Docket No. Z20886WO-01patient (e.g., red for high urgency or concern, yellow for moderate urgency or concern, green for low urgency or concern).

[0098] FIG. 3 illustrates an example customizable patient monitoring device 302 (in an enlarged size simplified view), including a monitoring device display 320 and multiple sensor ports, including 4 sensor agnostic data interface (DI) ports 308 and 4 smart ports 306, and multiple (conceptually depicted) connectable physiological parameter sensors 304 of various types, each or any of which may be communicatively connectable to one of the sensor agnostic data interface (DI) ports 308 or smart ports 306, as appropriate. Although not shown in FIG. 3, in some embodiments, the customizable patient monitoring device 302 may also include aNIBP port or module and / or a rotary dial, as described herein, and may include other controls or features.

[0099] The monitoring device display 320 includes an arrangement of display units, configured specifically as grid 316 of 6 tiles, including tile 310 and tile 320. Tile 310 is associated with a connected pulse oximetry7sensor for sensing patient SpO2, and tile 320 is associated with a connected respiratory rate sensor for sensing patient respiratory rate (RR). The displayed contents of each of the remainder of the tiles of the grid 316 are not illustrated, but some or each may display information associated with different connected physiological parameter sensors 304. As described herein, in some embodiments, one, some, or all of the grid 316 of tiles may display physiological parameter information, which may depend on the connected physiological parameter sensor associated with each tile. However, one or some of the tiles may not be associated with a physiological parameter sensor (or, in some embodiments, more than one physiological parameter sensor). In some embodiments, such tiles not associated with a physiological parameter may not be included, may be replaced by or more other display units or features, or may be used to display any of various information, such as additional information associated with other tile displays, or other information, or may not display any information. Furthermore, in some embodiments, a single attached phy siological sensor may sense multiple physiological parameters, in which case multiple tiles may be associated with the attached physiological sensor.

[0100] Still further, as described herein, in some embodiments, a user can configure and customize the grid 316 of tiles, such as by selecting (for example, via touch-based GUI features or controls, physical controls, or otherwise) which tile in the grid 316 is associated with each connected physiological parameter. Furthermore, in some embodiments, a user can customize the display of each tile (or some or all of the times), such as by selecting the specific type(s) of information to be displayed in the tile, or the format or specifics of theAttorney Docket No. Z20886WO-01display of the tile, or information (e.g., colors, symbols, text font type or size, location of specific type(s) of information within each tile, etc.).

[0101] As depicted, tile 310 displays information 314 including the sensed specific physiological parameter (SpO2) associated with the connected physiological parameter sensor that is associated with the tile, which is a pulse oximetry sensor, and a magnitude of the measured SpO2 (as depicted, 96%), and tile 320 also displays information 318 including the sensed specific physiological parameter (Respiratory rate - RR) associated with the connected physiological parameter sensor that is associated with the tile, which is a respiratoiy rate sensor, and a magnitude of the measured RR (as depicted, 25 breaths per minute - BPM). As described herein, each of the tiles, such as tiles 310 and 320, may also display other information (e.g., as conceptually represented by ellipses such as ellipsis 312), such as may be associated with the sensed specific physiological parameter, such as one or more early warning scores, alarm thresholds or sensor related alarms, as described herein.

[0102] FIG. 4A illustrates an example system 400 including a customizable patient monitoring device 414 (depicted at two different times) including, at time 1, a grid of tiles display 410, on the monitoring device display 430, displaying an arrangement of display items (specifically, a grid of tiles, such as tiles 402 and 432) and, at later time 2, a display, on the monitoring device display 430, including an enhanced display 412. The system 400 also includes a portable computing device 416 including an augmented display 418.

[0103] As depicted, the grid of tiles display 410 includes tile 402. which displays information including the sensed physiological parameter associated with tile 402 (SpO2) and a magnitude relating to the sensed physiological parameter (96%), and tile 432, which displays information including the sensed physiological parameter associated with tile 432 (RR) and a magnitude relating to the sensed physiological parameter (25 BPM).

[0104] As depicted, upon actuation by a user of a displayed tile of the grid of tiles, such as by touching tile 402, an enhanced display 412 is provided, associated with the actuated tile 402. In various embodiments, the enhanced display 412 may replace the entire grid 430 of tiles, a portion (such as one or several tiles) of the grid 430 of tiles, or may not replace any of the grid 430 of tiles. As depicted, the enhanced display 412 replaces the entire grid 430 of tiles. The enhanced display 412 may display additional information associated with the specific physiological parameter (SpO2) associated with the actuated tile 402, the additional information being in addition to the information displayed by the actuated tile 402 prior to actuation to display the enhanced display 412. However, in some embodiments, the enhanced display 412 may also display information including some or all of the informationAttorney Docket No. Z20886WO-01that is or was displayed on the actuated tile 402. As described herein, touching the tile 402 (or a portion or area thereof) to cause display of the enhanced display 412 may allow a care provider to easily, intuitively, and immediately display additional information associated with the information displayed by the tile 402, such as may be needed based on changes or developments relating to patient care, as described herein. It is noted that, while not described in detail herein, in some embodiments, any of various displays on the customizable patient monitoring device 414 may include multiple display features or controls allowing various user options, toggling, or customization relating to displays (or physiological parameter sensors). For example, in some embodiments, a user may touch a tile of a display to display an enhanced display, but may also toggle back to the associated grid of tiles display, such as by touching a different portion of the enhanced display. Furthermore, in some embodiments, the customizable patient monitoring device 414 may include multiple display screens.

[0105] In the depicted example, the additional information displayed by the enhanced display 412 includes a plot 408 including multiple measured SpO2 data points to represent a trend of the patient SpO2 over time, such as over a recent or current period of time, which may be used by the care provider in patient care, such as in, or to facilitate, assessing, diagnosing and / or treating the patient.

[0106] As depicted, in some embodiments, a user may actuate the enhanced display 412 (e.g., by touching the enhanced display or a specific and / or designated portion or area thereof) to cause display of an augmented display 418 on a computing device other than the customizable patient monitoring device 414, such as tablet 416. The augmented display 418 may display further information associated with the specific physiological parameter (SpO2) associated with the previously actuated tile 402 of the grid 430 of tiles display, and / or, in some embodiments, information associated with any information provided by the actuated tile 402 or enhanced display 418. The further information may be in addition, or partially in addition, to both the information displayed by the previously actuated tile 402 and the additional information displayed by the enhanced display 412. However, in some embodiments, the augmented display 418 may also include information displayed in the grid 430 of tiles display and / or the enhanced display 412. As described herein, touching the enhanced display 412 (or a portion or area thereof) to cause display of the augmented display 418 may allow a care provider (e.g., whether, for example, the care provider using the customizable patient monitoring device 414 and the tablet 416, or another care provider using the tablet 416, for example) to easily, intuitively, and immediately display further information associated with the information displayed by the tile 402 and the enhanced display 412, suchAttorney Docket No. Z20886WO-01as may be needed based on changes or developments relating to patient care, as described herein.

[0107] In the depicted example, the further information displayed by the augmented display 418 includes a photoplethysmography (PPG) waveform representing continuous change in patient SpO2 over a period of time, such as a recent or current period of time. The augmented display 418 may also include other information of various types, as conceptually represented by ellipses including ellipsis 424. It is noted that each display of the customizable patient monitoring device 414, tablet 416, including the augmented display 418, may include user selection options that allow, for example, changing or customization of the display, or to toggle or move back to previous or other displays, whether on the device being used or, in a system of devices, the device being used or another device in the system of devices.

[0108] In some embodiments, in addition to user actions on the customizable patient monitoring device 414 affecting, or causing action or actuation of, the tablet 416 (e.g., to display an augmented display, modify settings, etc.), user actions on the tablet 416 may affect, or cause action of actuation of, the customizable patient monitoring device 414 (or other devices in the system). For example, in some embodiments, a user of the tablet 416 may take actions that modify the display or other settings of the customizable patient monitoring device 414. For example, in some embodiments, a user may touch a portion of a display on the tablet 416 to cause the customizable patient monitoring device 414 to take some action. Such an action can be to initiate a NIBP measurement, or some other measurement by another connected sensor, for example, or to modify' or customize a display or grid of tiles 410 on the customizable patient monitoring device 414, or present an alert of alarm.Furthermore, such an action could be to zero or set a baseline for a specific parameter (e.g., IBP), e.g., setting a reference point or starting value against which later measurements can be compared. For example, a user of the tablet 416 may touch a specified portion or displayed item on the tablet to initiate some action or change on the customizable patient monitoring device 414, or to obtain one or more further GUIs on the tablet 416 to allow such.Additionally, in some embodiments, if a grid of tiles is displayed the customizable patient monitoring device 414 or the tablet 416, the user may be able to touch actuate a specific tile, or specific portion of a tile, that may include an associated display feature, to cause an action to be taken, or a change to be made on the other device. Additionally, in some embodiments, different touch protocols may initiate different actions, such as touching a tile once, or twice or three times quickly, or pressing and holding for a short period of time (e.g., 0.5, 1. 2 or 3 seconds), or swiping in a specific direction, or some combination or series of touch actions.Attorney Docket No. Z20886WO-01such as a quick touch followed by a press and hold touch, swiping a pattern of quick sliding movements in different directions, etc.

[0109] FIG. 4B illustrates an example display 450 on a computing device communicatively connected with (e.g., by wired or wireless connection) a customizable patient monitoring device, including display of an ECG waveform 454, a non-invasive blood pressure (NIBP) waveform 456, and an oxygen saturation (SpO2) waveform 458. The display 450 also includes various GUI based features 452 along atop portion of the display (e.g., controls, such as to access various other displays or features), and various GUI based features 460 along a side portion of the display (e.g., physiological parameters and their magnitudes, warnings, alerts, alarms, EWS information).

[0110] In the embodiment of FIG. 4B. the waveforms 454, 456, 458 are displayed on the display 450 of a computing device (e.g., a tablet) of a care provider, connected with the customizable patient monitoring device. However, in various embodiments, such waveforms 454, 456, 458, as well as other displayed items, may be displayed on any of various devices in a system including a customizable patient monitoring device, such as an enhanced display of the customizable patient monitoring device, for example. In various embodiments, the display 450 on the computing device may be presented upon a relevant user actuation, such as touch based actuation of a portion of a grid of tiles or enhanced display on the customizable patient monitoring device, touch based actuation of a portion of a previous display on the computing device, or touch based actuation of a portion of a display of another connected device in the system. In some embodiments, display of relatively complex items, such as may, in some cases, include waveforms, for example, may be advantageously presented on a computing device such as a tablet, which may advantageously present relatively complex or voluminous information, and may have a relatively large, high resolution display.[OHl] FIG. 5 illustrates example displays 554 with a grid of tiles 560, a display 556 with a trend plot 562, and a display 558 with a waveform 564 that may be displayed on a customizable patient monitoring device or connected device and / or one or more other coupled devices, such as a tablet. Display 554 illustrates grid of tiles 560 that as may be displayed on a customizable patient monitoring device, for example.

[0112] Trend plot 562 includes displayed markers 566, which may provide trend points, which may be calculated to provide a plot, set or curve of, or calculated based on, trend points over a recent period of time. As depicted, the trend plot 562 relates to patient heart rate. In various embodiments, for example, trend points may indicate values at specificAttorney Docket No. Z20886WO-01times, or, in other embodiments, trend points may be calculated based on, and take into account, a predetermined past time period, which may or may not go up to a present or last measurement time. For example, in some embodiments, statistical calculation methods may be used, taking into account values over time, some of which methods may use linear regression or other known mathematical techniques for trend calculation. In some embodiments, the trend plot 562 may be provided as, or as part of, an enhanced display on a customizable patient monitoring device. However, in other embodiments, the trend plot 562 may be provided as, or as part of, a display on another device (e.g., an augmented display on a tablet, for example).

[0113] In the embodiment depicted, on display 556, a user may touch the waveform icon 570 to obtain display 558 including waveform 564 (whether on the same device or another) associated with the trend, which, in this case, relates to patient heart rate over a period of time. In some embodiments, the display 558 may be provided as, or as part of, an augmented display on a device, such as a tablet, connected to a customizable patient monitoring device. However, in other embodiments, the display 556 may be provided as, or as part of, a display on the customizable patient monitoring device. As shown, the display 558 includes a trend plot icon 568 which may, for example, allow a user to toggle back to the display 556 including the tend plot 562 (whether on the same device or another).

[0114] FIGs. 6 and 7 illustrate example displays 600, 700 on a customizable patient monitoring device, including addition of a tile display associated with a physiological parameter. In FIG. 6, a grid of tiles display 602 is shown, as well ports, including 5 upper ports 604, 5 lower ports 606, and one side NIBP sensor port 610. The display 600 also includes a rotary dial 616, such as may be used as a physical secondary or backup control to touch-based GUI controls, for example. As depicted, physiological parameter sensors 608 (only a small portion of each are shown) are attached to all 5 upper ports 604 and one port 612 of the 4 lower ports 606. In the embodiment depicted, 7 of the 8 displayed tiles of the grid of tile display 602 include a display relating to a physiological parameter associated with one of the connected physiological sensors 608, 614. Each of the ports 604, 606, 610 may include any of a variety of physical and electrical connection components to facilitate physical and electrical connection of physiological parameter sensors. It is noted that tile 722, which is a bag valve mask (BVM) ventilation tile, 722 displays values for three physiological parameters, including inspiratory volume (Vi), expiratory' volume (Ve) and Respiratory’ Rate.

[0115] In the display 700 of FIG. 7, a capnography sensor 704 has been connected toAttorney Docket No. Z20886WO-01one of the lower ports that did not have a connected sensor in the display 600 of FIG. 6. Additionally, a corresponding tile 706 with EtCO2 information has been added to the display 700 of FIG. 7, relative to the display 600 of FIG. 6. In some embodiments, such a tile 654 may be automatically added to the display 700 upon connection of the capnography sensor 704, and may include information and a display format that may be a default or may be based on previous user customization settings, for example.

[0116] FIG. 8 illustrates an example displayed grid of tiles 800 of a customizable patient monitoring device. A total of 14 tiles display information on each of 14 different physiological parameters. It is noted that tile 802 displays values for three physiological parameters, including inspiratory volume (Vi), expiratory volume (Ve) and Respiratory' Rate, and tile 804 displays values for two different physiological parameters, including EtCO2 and Respirator}' Rate (RR). It is further noted that, while, in some embodiments, the number of sensors connected or enabled may match the number of tiles that display physiological parameter information, in other embodiments, fewer sensors may be connected or enabled than tiles that display physiological parameter information, such as when one or more sensors provide information regarding more than one physiological parameter. Furthermore, in other embodiments, more sensors may be connected or enabled than tiles that display physiological parameter information. For example, two or more sensors may be used in providing information regarding a single parameter, e.g., at different times or based on user selection, or if information from one sensor is used along with information from the other sensor, such as to confirm, refine or add to the information provided by the other sensor regarding the displayed physiological parameter information of the tile, for example.

[0117] In some embodiments, the displayed grid of tiles 800 may be display, in an integrated fashion, tiles relating to sensors from more than one customizable patient monitoring device, which may be connected or chained together, as previously described, as well as potentially from other connected devices. In various embodiments, the integrated display may be provided on one or both of the customizable patient monitoring devices, or may be customized on each device. For example, in some embodiments, one or more ports of a customizable patient monitoring device may be used to connect one or more other customizable patient monitoring devices. This may allow integration, within the system and displays of devices thereof, such as the displays of each of the customizable patient monitoring devices, of more physiological parameters, and tiles relating to them, than would be available using only a single customizable patient monitoring device. For example, if a single customizable patient monitoring device includes 8 ports, and if a sensor is connected toAttorney Docket No. Z20886WO-01each of the ports, and each sensor allows obtaining one parameter, then a maximum of 8 parameters may be displayed. However, if 7 of the ports are used for connected sensors and one of the ports is used to connect a second customizable patient monitoring device with 8 ports, using one of the ports of that device, then potentially 7 additional sensors may be connected to the second device. As such, a total of 14 connected sensors, and parameters obtained therefrom, may be integrated into the system as a whole, and the display of each device within the system, such as each of the two customizable patient monitoring devices, may include tiles and displayed parameters associated with any subset or all of the 14 connected sensors.

[0118] FIG. 9 illustrates example displays 900, including grids of tiles 908, 910, 912, of a customizable patient monitoring device, in which a tile is updated by a user to display a different physiological parameter of several physiological parameters that may be sensed from a single sensing device, such as SpO2 and pulse pressure variation (PPV). In the embodiment show n, a user chooses (e.g., by touch, double tap, tap and hold, etc.) a tile to be changed, in the initial grid of tiles 908, in this case displaying information relating to SpO2 902. Based on the chosen tile to be changed, a selection related grid of tiles 910 is displayed, which may replace (or partially replace, overlap, or partially overlap, for example) the previously displayed initial grid of tiles 908.

[0119] The selection related grid of tiles 910 includes multiple tiles from which the user can choose, each displaying different physiological parameter information. The user may select a specific tile, from the selection related grid of tiles 910, to replace the chosen tile from the initial grid of tiles 908. In the example show n, the user selects the tile displaying PPV information 904. As a result, an updated grid of tiles 912 is provided, which replaces the selection related grid of tiles 910. In the updated grid of tiles 912. the tile that had shown Spo2 information 902 is now updated to display PPV information 906.

[0120] In some embodiments, the updated grid of tiles 912 may then be used as a home or default display of the customizable patient monitoring device. It is noted that, in the selection related grid of tiles 910, a tile 916 includes displayed information relating to two physiological parameters, specifically, SpO2, with a value of 92%, and heart beats per minute (BPM), with a value of 85, both of which may, in various embodiments, be accessed using signals from one physiological parameter sensor (e.g., a pulse oximeter), or more than one.

[0121] FIG. 10 illustrates an example grid of tiles 1000 including displayed trend arrows 1002a-h) indicating trends associated with each of multiple patient physiological parameters. More specifically, each of the tiles 1000 displays information relating to aAttorney Docket No. Z20886WO-01specific physiological parameter, and each includes an arrow 1002a-h indicating a trend associated with the specific physiological parameter. Various techniques that may be used in calculation of trends and trend points is described with reference to FIG. 5 herein.

[0122] In some embodiments, inclusion of trend arrows, such as on tiles of a home or default grid of tiles display, may be especially useful in emergency, such as military' or mass casualty, environments and situations. For example, with a grid of tiles including trend arrows, a care provider can immediately view values for any of the physiological parameters associated with any of the tiles, and can also, without any needed input or change of display, immediately notice and view trends associated with any displayed physiological parameters that may be currently of critical importance. Furthermore, in some embodiments, the user may quickly select a specific tile to obtain more detailed information on the associated physiological parameter(s), such as via an enhanced display on the customizable patient monitoring device, and / or an augmented display on another device. Additionally, in some embodiments, for example, visual, audio or tactile advisories, alerts, and / or alarms may presented by the customizable patient monitoring device (or a connected device), as may relate to a displayed physiological parameter that may have a value that is so high or low that it triggers such presentations, e g., to alert the care provider of a critical or life-threatening condition of the patient.

[0123] FIG. 11 illustrates an example of a tile, in grids of tiles 1106a-c. that may be used to display a selected physiological parameter. More specifically, tile 1104 is first used to provide a display 1102a of heart rate (HR) information, a display 1102b of temperature information, or a display 1102c of SpO2 information 1102c, for example, depending on user selection. In some embodiments, the customizable patient monitoring device selects a particular sensor to be linked to the tile 1104 based on the selected parameter to be displayed (e.g., non-invasive blood pressure sensor for HR, temperature sensor for temperature, or pulse oximetry sensor for SpO2). In the embodiment depicted, at the top right of the tile 1104, a series of images including one circle and two dots is displayed, where the position of the circle in the series is used to indicate which of the three displays for the tile is currently selected and being displayed.

[0124] In some embodiments, a user can select or toggle between different variations 1106a-c of the grid of tiles, where, in each variation, one or more tiles, such as tile 1104, is used to display information relating to a different one or more physiological parameters. For example, the user may pre-configure each of the variations 1106a-c of the grid of tiles, so that, when one of them is needed, based on a current clinical situation, the user can quicklyAttorney Docket No. Z20886WO-01select or toggle to it. In some embodiments, the selected grid of tiles may then become a default or home display on the customizable patient monitoring device.

[0125] As described herein, including with reference to FIG. 8, in some embodiments, one or more of the ports of a customizable patient monitoring device may be used to connect one or more other such devices, using one or more of the ports thereof, and potentially even more such devices may be connected even more such devices, allowing "chaining” together of the devices and availability, integrated with the system as a whole, of many more physiological sensors and obtained parameters than would be available from a single customizable patient monitoring device. In some examples, in FIG. 11, the displays 1106a-c may reflect parameters obtained from multiple customizable patient monitoring devices, and the displays I I06a-c may displayed on one or several of the devices. For example, in each of the displays 1106a-c, some of the displayed parameters may be obtained from one or more sensors connected to one customizable patient monitoring device, while others may be obtained from one or more other such devices. For instance, the available parameters 1102a-c may be obtained from sensors connected to one or several customizable patient monitoring devices.

[0126] FIG. 12 illustrates an example early warning score (EWS) related display 500 of a monitoring device display of a customizable patient monitoring device, including a set of early warning scores (EWSs) and other displayed information. The display 500 is an example of any of various displays that may be provided by the monitoring device display, such as may be selected, actuated or requested by a user, such as using GUI based or physical controls of the customizable patient monitoring device or the monitoring device display thereof, or in other ways. In some embodiments, for example, specific displays may be provided based on user actuation of a display, or portion thereof, to display another display or a portion thereof (e.g., actuation relating to a tile of a grid of tiles relating to connected physiological parameter sensors and / or associated measured physiological parameters may cause display of an enhanced display, or actuation relating to an enhanced display may cause display of an augmented display on a connected device). In some embodiments, various displays, such as display 500, may replace or partially replace some or all of the tiles of another grid of tiles based display, or other display (e.g., a grid of tiles relating to connected physiological parameter sensors and / or associated measured physiological parameters)

[0127] The display 500 includes grid 504 of EWS related tiles 506, as well as various additional display portions above, below, to the left, and to the right of the grid 504 of EWS related tiles. A display portion 528 below the grid 504 of EWS related tiles 506 may be used.Attorney Docket No. Z20886WO-01for example, to provide basic display selectable / actuatable features, such as to enable navigation between displays.

[0128] In a display portion to the left of the grid 504 of EWS related tiles 506, selectable / actuatable display areas / features are displayed, e.g., with text and icons / symbols. These may include various specific display areas / features, such as may be associated with the display 500 or multiple displays including the display 500 (or displays of one or more connected devices), and, in some embodiments, may be customizable by a user (e.g., including display format and content aspects, for example). Display area / feature 520 (or, e g., a portion thereof) may be selected / actuated, for example, to obtain guidance, such as may relate, for example, to any of various aspects of treatment being provided to the patient (e.g., in defibrillation, placement of electrodes on the patient). Display area / feature 522 may be selected / actuated, for example, to obtain an EWS related display, such as the depicted display 500 or grid 504 of EWS related tiles 506. Display area / feature 524 may be selected / actuated, for example, to obtain a treatment related display, such as may relate to a treatment(s) being administered to the patient and details thereof. Display area / feature 526 may be selected / actuated, for example, to obtain a patient related display, such as may provide patient details such as identity related information, basic physiological information (e.g., patient gender, height and weight), patient conditions (e.g., medical conditions), or other information.

[0129] A display portion 538 to the right of the grid 504 of EWS related tiles 506 may be used to display various patient physiological parameter related information. For example, in some embodiments, a user can customize this display portion 538 to include a tile-based display of, or relating to, some (e.g., selected) or all of a display including a grid of tiles relating to a physiological parameter associated with some or all connected physiological parameter sensors (examples of which are provided in FIGs. 3 and 4 herein). In the example shown, tile 530 displays heart rate (HR) and a measured magnitude (rate) of 101 beats per minute (BPM); tile 532 displays SpO2 but no measurement (e.g., the pulse oximetry sensor may not currently be attached to the patient or may not be currently taking measurements): tile 534 displays EtCO2 but no measurement (e.g., the capnography sensor may not currently be attached to the patient or may not be currently taking measurements); and tile 536 displays respiratory rate (RR) and a magnitude of 25 beats per minute (BPM). T

[0130] Tiles 530-536 display the word “Manual.’' This may indicate that the associated physiological related parameters are set to manual entry. For example, some physiological parameters may be obtained by a care provider manually or using one or moreAttorney Docket No. Z20886WO-01devices not connected (or not connectable) to a system including a customizable patient monitoring device, and entered into a device in the system for integration into the information stored and used in the system. For example, in some cases, a physiological parameter, such as SpO2, may be obtained by a care provider, such as by using a pulse oximeter that may not be connected, or may not be connectable, for various possible reasons, to the system including a customizable patient monitoring device. As another example, during treatment of a patient, a care provider may manually draw blood from the patient and test the drawn blood to obtain test results that may include physiological parameters, e.g., regarding constituents and levels of constituents in the draw n blood, such as lactate, hematocrit, or glucose, for example. The results may need to be manually entered by the care provider.

[0131] Furthermore, in some embodiments, a care provider may be provided with one or more GUIs to enable selection of a manner or specific device by which selected physiological parameter information of the patient may be obtained by the system including the customizable patient monitoring device. For example, as shown in FIG. 12, a GUI feature including table 542 may be displayed, such as upon the care provider touch actuating tile 536, which displays patient respiratory rate (RR). The table 542 may display various options available to the user in this regard. For example, if “manual” is chosen, then the parameter may be measured and entered by the care provider (which may, in some cases, include use of a device that is not communicatively connected or not communicatively connectable to the system, for example). However, using table 542, the care provider may select one of several devices connected to the system, which may provide signals that may allow access or computation of the specific parameter (in this case, RR). For example, table 542 lists options, besides manual entry, of use of a flow sensor, ECG electrodes, an invasive blood pressure sensor, or a capnography sensor (one or which may be selected by touch, for example). If the user selects an option other than manual, then the tile 536 may be updated to display the selected option instead of “Manual.”

[0132] Furthermore, in some embodiments, a user may be provided with options including particular physiological parameters (in some cases, independent of selection of a device) from which the specific physiological parameter may be determined, or the user may¬ be provided with options for the device used and the particular parameter used (e.g., respiratoiy rate (RR) may be obtained, such as accessed or computed, using signals from sensors such as a patient airway airflow sensor, a capnograph, an invasive blood pressure (IBP) sensor, or electrodes used to determine an ECG w aveform). For example, in some instances or situations, one device and / or particular parameter(s) may allow computation ofAttorney Docket No. Z20886WO-01the specific parameter (e.g., RR) with lower accuracy, while another device and / or particular parameter(s) may allow computation of a specific parameter (e.g., RR) with a higher accuracy, in which case the care provider may select the higher accuracy option, for example.

[0133] The display portion 538 also displays actuatable display areas / features 542, 544 and 546. Display area / feature 542 may, for example, be selected / actuated to obtain a display providing information about devices connected to the customizable patient monitoring device, and may provide details relating to the connected devices. Display area / feature 544 may, for example, be selected / actuated to obtain a display providing information or details about the patient. Display area / feature 546 may, for example, be selected / actuated to obtain synchronize the customizable patient monitoring device, such as by obtaining and incorporating information from resources, devices or databases outside of the customizable patient monitoring device. Display area / feature 540 (a ‘'home” symbol), may, for example, be selected / actuated to return to an initial or home display, such as, in some embodiments, a display including a grid of tiles relating to a physiological parameter associated with some or all connected physiological parameter sensors (examples of which provided in FIGs. 3 and 4 herein).

[0134] FIG. 13 is a flow diagram illustrating a method 500 for display of an arrangement of display items and an enhanced display on a customizable patient monitoring device, and including display of an augmented display on a computing device, such as may¬ be implemented or facilitating by or using a software-based or code-based monitoring director 512 of the customizable patient monitoring device.

[0135] At step 501, physiological parameter data is obtained by the customizable patient monitoring device from signals from connected physiological parameter sensors. At step 502, an arrangement of display items is displayed on the monitoring device display, including obtained physiological parameter data associated with each of the connected physiological sensors.

[0136] At step 504, the method 500 queries, has the user actuated a display unit (e.g., a tile of a grid of tiles) on the monitoring device display of the customizable patient monitoring device to display an enhanced display? If so, then, at step 506, an enhanced display (as described herein) is displayed that is associated with a selected display unit (e.g., a tile) on the monitoring device display. If not, then the method 500 returns to step 502.

[0137] At step 508, the method 500 queries, has the user actuated the enhanced display, or a portion thereof, on the monitoring device display- to display an augmented display, such as on a portable computing device communicatively connected to theAttorney Docket No. Z20886WO-01customizable patient monitoring device? If so, then, at step 510, an augmented display is provided on a portable computing device, the augmented display being associated with a selected display unit (e.g., a tile) on the monitoring device display. If not, then the method 500 returns to step 506.

[0138] FIGs. 14-19 are flow diagrams 1400-1900 illustrating methods for accessing and / or computing, and displaying, information, such as physiological information, on one or more devices of a system including a customizable patient monitoring device. In some embodiments, the methods may be performed by a monitoring director of the customizable patient monitoring device. It is noted that, in FIGs. 14-19, some of the steps may be implemented in serial fashion, whereas other of the steps may be implemented in a parallel fashion as relates to other steps, e.g., before, after, simultaneously or partially simultaneously with one or more other steps.

[0139] FIG. 14 is a How diagram illustrating a method 1400 for obtaining and displaying physiological parameter information that may be implemented by a software or code-based monitoring director 1402 of a customizable patient monitoring device, which may include accessing and / or computing information to be displayed.

[0140] At step 1404, signals are received by a customizable patient monitoring device from an accessory, such as from a connected physiological parameter sensor (or from each of multiple connected sensors) or from another device (e.g., a defibrillator, patient monitor ventilator) or accessory. For each sensor, the customizable patient monitoring device may detect (which may include identifying) the specific connected sensor or type of sensor, and may also perform authentication with regard to each connected sensor, which may include, e.g., verifying the identity of the sensor and appropriate credentials use with the customizable patient monitoring device.

[0141] At step 1406, the customizable patient monitoring device processes the signals to access and / or compute information, such as physiological related information.

[0142] In some embodiments, step 1410 and / or step 1412 are included in the processing of step 1406 to access and / or compute information, such as physiological information (e.g., physiological parameter values, waveforms, or other information).Specifically, in some embodiments, the customizable patient monitoring device may use software or code to access (e.g., recognize) physiological information, which may be displayed. Additionally or alternatively, in some embodiments, the customizable patient monitoring device may use software, such as may include selecting and applying one or more software based libraries, such as along with accessed information and / or other availableAttorney Docket No. Z20886WO-01information (e.g., computed information, sensor signals), to compute other physiological information which may also be displayed. Herein, use of software, such as a selected library, in computing information based at least in part on received signals may include use of the received signals themselves, or may not. For example, use of software, such as a selected library in computing information based at least in part on received signals may include use of the received signals themselves, or may alternatively include use of information accessed using the received signals, without use of the received signals themselves. Furthermore, use of the received signals may include use of at least a portion of the received signals, and not using the received signals indicates that no portion of the received signals is used.

[0143] In some embodiments, in a particular instance, the monitoring director 1402 may select the one or more libraries (e.g., software or code based) used in computing the other physiological information, based on factors that may include one or more of: the accessed information to be used or selected to be used, the sensor(s) associated with the accessed information to be used, other sensor(s) or other accessed information to be used or selected to be used, other system related information, other environment related information, other treatment related information, other patient related information, and / or other information or factors.

[0144] In some instances, at step 1406, software is used in accessing physiological related information from the signals received at step 1404, for display.

[0145] In some instances, additionally or alternatively, at step 1410, one or more selected software libraries, and accessed physiological related information, are used to compute other physiological related information for display. In various instances, the accessed physiological information used at step 1410 may be that of step 1406 or may be different physiological information accessed by the customizable patient monitoring device using the signals received at step 1404, or both.

[0146] At step 1412, the customizable patient monitoring device causes display of the physiological related information accessed at step 1408 and / or the physiological information computed at step 1410, such as on the customizable patient monitoring device or a connected device (e.g., a tablet).

[0147] In some embodiments, connectable sensors, any of which may be connected to any port, may include, among others, a non-invasive blood pressure (NIBP) sensor, an invasive blood pressure (IBP) sensor, a capnograph, a pulse oximeter, a sensor that senses flow rate, a sensor that senses pressure, a temperature sensor, and one or more electrodes.

[0148] Furthermore, in some embodiments, connectable sensors may enableAttorney Docket No. Z20886WO-01measurement of, among other things, non-invasive blood pressure (NIBP), systolic blood pressure, diastolic blood pressure, mean arterial pressure (MAP), invasive blood pressure (IBP), pulse rate (PR), pulse pressure variation (PPV), respiratory rate (RR), end-tidal carbon dioxide (EtCO2), capnogram waveform, oxygen saturation (SpO2), photoplethysmography (PPG) waveform, a pleth waveform, a hypovolemia compensation measurement, inspiratory- volume (Vi), expiratory volume (Ve), peak inspiratory- pressure (PIP), temperature, heart rate (HR), ECG waveform, heart rate variability (HRV), and amplitude spectrum area (AMSA).

[0149] In some embodiments, in various cases, information, such as clinically presentable physiological information, may be accessed or computed using received signals from a non-invasive blood pressure (NIBP) sensor. The accessed information may include, for example, systolic blood pressure, diastolic blood pressure, and / or mean arterial pressure (MAP). The computed information may include, for example, mean arterial pressure (MAP).

[0150] For example, in some embodiments, MAP may be computed from systolic blood pressure (SBP) and diastolic blood pressure (DBP (e.g., as obtained from an invasive blood pressure (IBP) sensor or a non-invasive blood pressure (NIBP) sensor), using the following equation:(Equation 1)MAP = (SBP + 2 x DBP) / 3

[0151] Equation 1 accounts for the fact that diastole lasts about twice as long as systole.

[0152] In some embodiments, pulse pressure variation (PPV), as a percentage may be computed using the following equation:(Equation 2)PPV (%) = {[PP (max) - PP(min)] / [(PPmax + PPmin / )2]} x 100

[0153] In Equation 2, PP(max) is the maximum pulse pressure during a respiratory cycle and PP(min) is the minimum pulse pressure during the respiratory cycle. PP may- be obtained from signals received from an invasive blood pressure (IBP) sensor, where PP = SBP - DBP.

[0154] In some embodiments, in various cases, information, such as clinically presentable physiological information, may be accessed or computed using received signalsAttorney Docket No. Z20886WO-01from an invasive blood pressure (IBP) sensor. The accessed information may include, for example, systolic blood pressure, diastolic blood pressure, and / or mean arterial pressure (MAP). The computed information may include, for example, mean arterial pressure (MAP), pulse pressure variation (PPV), respiratory rate (RR), and / or pulse rate (PR).

[0155] In some embodiments, in various cases, information, such as clinically presentable physiological information, may be accessed or computed using received signals from a capnograph. The accessed information may include, for example, EtCO2. The computed information may include, for example, a capnogram waveform.

[0156] In some embodiments, in various cases, information, such as clinically presentable physiological information, may be accessed or computed using received signals from a pulse oximeter. The accessed information may include, for example, SpO2 and / or a photoplethysmography (PPG) waveform. The computed information may include, for example, a photoplethysmography (PPG) waveform, pleth waveform, pulse rate (PR), pulse pressure variation (PPV), a hypovolemia compensation measurement, and / or respiratory rate (RR)

[0157] In some embodiments, in various cases, information, such as clinically presentable physiological information, may be accessed or computed using received signals from a sensor that senses flow rate (potentially among other things, such as pressure), such as flow rates associated with a ventilator or a patient undergoing ventilation treatment. The accessed information may include, for example, respiratory rate (RR). The computed information may include, for example, inspiratory' volume and / or expiratory volume.

[0158] In some embodiments, in various cases, information, such as clinically presentable physiological information, may be accessed or computed using received signals from a sensor that senses pressure (potentially among other things, such as pressure), such as pressure associated with a ventilator or a patient undergoing ventilation treatment. The computed information may include, for example, peak inspiratory' pressure (PIP).

[0159] In some embodiments, in various cases, information, such as clinically presentable physiological information, may be accessed or computed using received signals from a temperature sensor. The accessed information may include, for example, temperature (e.g., of the patient).

[0160] In some embodiments, in various cases, information, such as clinically presentable physiological information, may be accessed or computed using received signals from one or more electrodes. The accessed information may include, for example, an ECG waveform and / or heart rate. The computed information may include, for example, an ECGAttorney Docket No. Z20886WO-01waveform, heart rate (HR), respiratory rate (RR), heart rate variability' (HRV), and / or amplitude spectrum area (AMSA).

[0161] FIG. 15 is a flow diagram illustrating a method 1500 for obtaining and displaying physiological parameter data that may be implemented by' a monitoring director 1502 of a customizable patient monitoring device, including accessing of physiological parameter information and computation of a waveform.

[0162] At step 1504, signals are received by a customizable patient monitoring device from a connected physiological sensor coupled with a patient.

[0163] At step 1506, the monitoring director 1502 queries, is a specific software library needed to compute a desired specific physiological parameter and its magnitude (e.g., SpO2, EtCO2, HR, etc.)? If a library is not needed, then, at step 1508, the monitoring director 1502 accesses the physiological parameter and its magnitude from the received signals. However, if a library' is needed, then the method 1500 proceeds to step 1510.

[0164] At step 1510, based at least in part on the received signals, the monitoring director 1502 selects an applicable waveform computation library from memory, e g., a library that will allow computation of the physiological parameter and its magnitude using the received signals, or using the received signals and other available physiological information.

[0165] At step 1512, the monitoring director 1502 applies (e.g., executes) the selected waveform computation library to determine a waveform needed to compute the physiological parameter and its magnitude (e.g., a physiological related waveform, such as an CO2 waveform, photoplethysmography (PPG) waveform, etc.)

[0166] At step 1514, the monitoring director 1502 applies (e.g., executes) the selected waveform computation library in analyzing the determined waveform to compute the physiological parameter and its magnitude.

[0167] At step 1516, the monitoring director 1502 outputs the physiological parameter and its magnitude to be displayed.

[0168] At step 1518, the accessed specific physiological parameter and its magnitude are displayed on a customizable patient monitoring device, and / or another connected device.

[0169] In some embodiments, a monitoring director of a customizable patient monitoring device may determine how to, or the most efficient manner of, obtaining information from a sensor or other device, such as may include accessing or computing information, and such as may depend, among other things, on the associated connected sensor (which, in some cases, may be selected by a user) or information to be accessed or computed.Attorney Docket No. Z20886WO-01potentially among other factors.

[0170] In some embodiments, a monitoring director of a customizable patient monitoring device may obtain physiological information (e.g., clinically presentable physiological information) by accessing the information from signals received from a sensor, or by computing the information using the sensor signals, potentially along with other information. Accessing the information from the sensor signals may include using software to recognize and identify information conveyed by the signals (e.g., SpO2 and its magnitude).

[0171] However, in some cases, the sensor signals do not include or convey the desired physiological information. None the less, the monitoring director may be able to use the sensor signals, potentially along with other available information, to obtain the desired physiological information by computation, which may require one or more steps. In some embodiments, the monitoring director may select an appropriate software library, among many stored in memory, to be used in this regard. In the example provided in FIG. 15, an appropriate waveform computation library is selected at step 1 10. This waveform computation library may allow determination of a specific waveform that can be used to compute the desired clinically presentable physiological information. In particular, in the example provided in FIG. 15, the determined waveform may be analyzed at step 1514 to compute the desired clinically presentable physiological information, which is then output at step 1516 to be presented at step 1518.

[0172] However, in other examples, a software library may be selected that is other than a waveform computation library, and steps 1512 and 1516 may be omitted or differ. However, the selected library may use the sensor signals, potentially along with other information, to compute desired clinically presentable physiological information, which may not be accessible from sensor signals.

[0173] More generally, in some embodiments, the monitoring director may select an appropriate library to allow computation of physiological information, such as clinically presentable physiological information, where such information is not accessible from sensor signals. In various embodiments, one or several steps may be included in the computation of the physiological information using the library.

[0174] FIGs. 16-19, described in detail below, provide specific examples of use of specific libraries to compute specific desired clinically presentable physiological information.

[0175] FIG. 16 is a flow diagram illustrating a method 1600 for obtaining and displaying physiological parameter data that may be implemented by a monitoring director 1602 of a customizable patient monitoring device, including use of electrode signals, andAttorney Docket No. Z20886WO-01including accessed and computed physiological related information.

[0176] At step 1603, signals are received by a customizable patient monitoring device from one or more electrodes coupled with a patient (e.g., of the customizable patient monitoring device or a defibrillator with connected electrodes, for example).

[0177] At step 1604 (which may be implemented, e.g., before, after, simultaneously with, or partially simultaneously with step 1622 and / or other steps), based on the received signals, ECG waveform information is accessed or, e.g., if necessary, computed, e.g., using one or more selected ECG computation libraries, potentially among other things. At step 1606, based on the ECG waveform information, intervals between heart beats are computed. As shown in feature 1612, this may include, for example, identifying heart beat related peaks in the ECG waveform, and determining intervals of time between adjacent peaks. At step 1608, an appropriate heart rate variability (HRV) computation library is selected for computation of a HRV of the patient using, potentially among other things, some or all of the signals and information obtained at step 1604 and / or 1606. At step 1610, the HRV computation library, along with information obtained at step 1606, potentially among other information, is used in computing the HRV of the patient.

[0178] In particular, HRV may be calculated by determining and using time intervals between successive heartbeats from the ECG waveform, known as R-R intervals (as described further below). Any of several different statistical methods may then be applied to compute a level of variability as relates to the different R-R intervals. For example, time domain analysis and metrics may be used in this regard, such as the standard deviation of all recorded intervals (e.g., using NN intervals, or times between normal heartbeats, as determined based on R-R intervals but excluding unreliable R-R intervals), root mean square of successive differences between NN intervals, or percentage of successive NN intervals differing by more than a specific amount, such as 50 ms. Other methods may also be used, such as use of frequency domain analysis (e.g., use of spectral analysis to assess variations in different frequency bands), or non-linear methods (e.g., analysis of complex patterns in heart rate dynamics).

[0179] At step 1614, using the accessed or computed ECG waveform information, low' frequency information of the ECG waveform is computed (as conceptually shown in image 1615). At step 1616, a heart rate (HR) library' is selected for computation of a HR of the patient. At step 1618, the selected HR computation library', along with the information obtained at step 1614, potentially among other information, is used in computing a HR of the patient.Attorney Docket No. Z20886WO-01

[0180] For example, in some embodiments, the R-R intervals may be used to compute the HR from the low frequency ECG information. In particular, the method, which may be implemented by the monitoring director using the heart rate computation library, may include the following steps. First, using the low frequency ECG information (e.g., a waveform), R wave peaks are identified, which correspond to ventricular depolarizations. Next, R-R intervals are measured, by calculating the dime difference between consecutive R waves. HR may then be calculated using the following equation.(Equation 3)HR (in BPM) = 60 / R-R interval (in seconds)

[0181] At step 1622, using the received sensor signals, specific physiological parameter information (e.g., SpO2 or EtC02 information) is accessed (which may be implemented, e.g., before, after, simultaneously with, or partially simultaneously with steps 1604 and / or other steps).

[0182] At step 1620, the ECG waveform, the computed HRV and HR, and the accessed physiological parameter information (e.g., a physiological parameter and measured value thereof) are displayed on device(s) in system including a customizable patient monitoring device (e.g., on the customizable patient monitoring device and / or one or more other devices in the system).

[0183] FIG. 17 is a flow diagram illustrating a method 1700 for obtaining and displaying physiological parameter data that may be implemented by a monitoring director 1702 of a customizable patient monitoring device, including use of pulse oximeter signals, and including and access of several other physiological parameters and computation of several physiological related parameters.

[0184] At step 1704, signals are received by a customizable patient monitoring device from a pulse oximeter couple with a patient (e.g., attached to a finger of the patient).

[0185] At step 1706 (which may be implemented, e.g., before, after, simultaneously wi th, or partially simultaneously with step 1716 and / or other steps), based on the received signals, potentially among other information, photoplethysmography (PPG) waveform information is accessed or, e.g., if necessary, computed, e.g., using one or more selected photoplethysmography (PPG) waveform computation libraries, potentially among other things. At step 1708. an appropriate respiratory rate (RR) computation library is selected for computation of a RR of the patient. At step 1710, using the selected RR computation library,Attorney Docket No. Z20886WO-01along with the photoplethysmography (PPG) waveform information, potentially among other information, the respiratory rate (RR) of the patient is computed.

[0186] At step 1712, an appropriate hypovolemia compensation computation library is selected for a hypovolemia compensation measurement relating to the patient, e.g., which may measure the patient’s compensatory response to fluid loss, such as blood loss. The hypovolemia compensation measurement may be expressed, for example, as a percentage, where the higher the percentage, the higher the risk of shock. An example of a hypovolemia compensation measurement is compensatory reserve measurement (CRM). At step 1714, the selected library', along with the computed RR, potentially among other information, is used in computing the hypovolemia compensation measurement for the patient.

[0187] For example, in some embodiments, hypovolemia is estimated based on a RR range, since, as hypovolemia progresses, RR typically increases due to reduced oxygen delivery and metabolic acidosis. For example, a RR of 10-20 BPM (or more or less) may be assessed to correspond with mild hypovolemia, a RR of 20-30 BPM (or more or less) may be assessed to correspond with moderate hypovolemia, and a RR of 35-40 BPM (or more or less) may be assessed to correspond with severe hypovolemia. Furthermore, a hypervolemia compensation measurement may be computed based on the assessed degree of hypovolemia, where a higher degree of hypovolemia generally corresponds to, or may be assessed as proportional to, a higher hypovolemia compensation measurement. In some embodiments, other information may also be taken into account in computing a hypovolemia compensation measurement, such as HR or BP.

[0188] At step 1716, using the signals received at step 1704, patient pulse rate and SpO2 information is accessed.

[0189] At step 1718, RR, hypovolemia compensation measurement, PR and SpO2 information (e.g., including values for each) is displayed on device(s) in system including a customizable patient monitoring device.

[0190] FIG. 18 is a flow diagram illustrating a method 1800 for obtaining and displaying physiological parameter data that may be implemented by a monitoring director 1802 of a customizable patient monitoring device, including use of airway flow and pressure signals, and including computation of a several physiological related parameters and access of several other physiological parameters.

[0191] At step 1803, signals are received by a customizable patient monitoring device from an airway flow and pressure sensor (e.g., an Accuvent sensor available from ZOLL Medical Corporation) coupled to the airway of a patient, which may be used in ventilationAttorney Docket No. Z20886WO-01treatment being provided to the patient.

[0192] At step 1804, using the received sensor signals, airway pressure and temperature information is accessed (which may be implemented, e.g., before, after, simultaneously with, or partially simultaneously with step 1810 and / or other steps).

[0193] At step 1806, an appropriate peak inspiratory pressure (PIP) computation library is selected for computation of PIP. At step 1808. the selected PIP computation library, along with information obtained at step 1804, potentially among other information, is used in computing the PIP. At step 1810, which may be implemented, e.g., before, after, simultaneously with, or partially simultaneously with step 1804 and / or other steps), using the signals received at step 1803, potentially among other information, inspiratory volume (Vi), expiratory volume (Ve) and RR are accessed or computed.

[0194] For example, PIP may be computed by integrating flow and resistance information. For example, in some embodiments, PIP may be computed using the following equation.(Equation 4)PIP = inspiratory flow rate (Q) x airway resistance (R) + positive end-expiratory pressure (PEEP).

[0195] Airway resistance may be determined based on a relationship between pressure and flow measurements, and PEEP may be determined based on analysis of airflow pressure at the end of expiration, when airflow equals zero.

[0196] At step 1812, airway pressure and temperature, PIP, Vi, Ve and RR information (e.g., including values for each) is displayed on device(s) in system including a customizable patient monitoring device.

[0197] Referring to FIG. 19, an example of a data transfer cable compatible with a sensor-agnostic data interface port for transferring sensor data to a device 110 (e.g., a customizable patient monitoring device or other connected device) is shown. The data transfer cable 210 is configured to provide at least power transmission and data communications between a sensor 220 (e.g., sensors 304 as shown in FIG. 3) for collecting sensor data and a sensor-agnostic data interface (DI) (e.g. sensor agnostic data interface (DI) ports 202 and / or 204 as shown in FIG. 2) associated with a device 110.

[0198] The data transfer cable 210 compatible with the SA-DI port 298 includes a flexible cable 230 constituting conductive wires (e.g., wires 240 a, 240 b, 240 c, and 240 d)Attorney Docket No. Z20886WO-01disposed within a continuous insulative sheath 245. The conductive wires may include single strands and / or multi-strands of one or more conductive materials. The number of wires shown in FIG. 19 is an example only and not limiting of the disclosure. The cable 230 may be fixedly fastened to a first electromechanical connector 250 at a first end of the cable 230 and to a second electromechanical connector 290 at a second end of the cable 230.

[0199] The first electromechanical connector 250 may include a housing 252 and an electrical mating 254 (e.g., a first electrical mating) disposed within the housing 252 at an open end of the housing distal from the cable 230. In other words, the cable 230 connects to the housing at a first end of the housing and the electrical mating 254 for the sensor is disposed in a second and different end of the housing. The electrical mating 254 is configured to detachably couple to the sensor 220 (e.g.. to an electrical connector 225 associated with the sensor 220). The electrical mating 254 provides electrical coupling between one or more contacts 226 associated with the sensor and one or more contacts 256 associated with the data transfer cable 210. The combination of the electrical mating 254 and the electrical connector 225 may be. for example, a pin / socket combination, a plug / jack combination, a card edge / spring contact combination, etc.

[0200] The first electromechanical connector 250 also includes data interface circuitry 260 disposed within the housing 252. FIG. 19 schematically illustrates the data interface circuitry 260 in the first electromechanical connector 250 and also illustrates components of the data interface circuitry 260 as an inset box with a blown-up view of the data interface circuitry 260. The data interface circuitry is electrically coupled to the electrical mating 254 by one or more electrical contacts 256 and is electrically coupled to the conductive wires (e.g., wires 240 a, 240 b, 240 c, and 240 d) of the cable 230. The data interface circuitry 260 includes a cable processor 265. a cable memory 266, and cable patient leakage current isolation 270. In an implementation, the data interface circuitry 260 includes an analog-to-digital (A / D) converter circuit 269 configured to convert analog signals from the sensor 220 to digital signals for the cable processor 265. The A / D converter is shown separately from the cable processor 265 for clarity but may be integrated into the cable processor 265.

[0201] The cable patient leakage current isolation 270 comprises an isolation device 270 and / or circuitry’ and other hardware and / or physical components configured to limit patient leakage current flow' from the device 110 to the patient via the sensor 220. Particularly’ for high voltage electrotherapy, leakage current isolation can be beneficial for safety reasonsAttorney Docket No. Z20886WO-01

[0202] In FIG. 19, the isolation device 270 and / or circuitry may include an isolation barrier device, for example a double capacitive isolation barrier device, a digital isolator device, an optical isolator device, etc. The isolation device 270 is configured to transmit power signals 274 and communication signals 276 across an isolation barrier 278. These devices are examples only and not limiting of the disclosure. The hardware and / or physical components may include without limitation conductive and insulative layers and / or coatings coupled to and / or surrounding the isolation device 270 and / or circuitry.

[0203] The isolation device 270 is configured to transmit power 274 uni-directionally across an isolation barrier 278 towards the cable processor 265. When the data transfer cable 210 is coupled to the device 110 via the SA-DI port 298, the device 110 may be the sensor power source and may provide power 274 to the cable processor 265 andthe sensor 220 via the port 298 and the data transfer cable 210. For example, the data transfer cable 210 may transmit power 274 via at least one conductive wire 240 d withanother wire 240 c at ground. The isolation device 270 may transfer this power 274, transmitted by the data transfer cable 210 from the device 110, across the isolation barn er 278 in one direction to the cable processor 265 and the sensor 220. With this unidirectional power transfer, there is substantially limited or no transmission of power from the processor side of the isolation 270 tow ards the device 110. In an implementation, the isolation device 270 may transfer, or transmit, 0.1-1 Watts of pow er 274 across the isolation barrier 278. In an implementation, the isolation device 270 is configured to transmit an amount of power 274 across the isolation barrier 278 that is specific to the pow er requirements of the sensor 220. For example, an invasive blood pressure sensor may require approximately 0.2 Watts whereas a flow sensor may require approximately 0.5 Watts. Thus, the power transmission capability of the isolation device 270 is tailored to the power requirement of the sensor 220. As a result, the device 110 may be configured to apply power in an amount compatible with a variety of sensors to the SA-DI port 298.

[0204] The isolation device 270 is also configured to transmit communication signals 276 bi-directionally across the isolation barrier 278. The bi-directional nature of this transmission enables the device 110 to be a source of communication signals and send information via these signals to the cable processor 265 and the sensor 220. Similarly, this bidirectionality enables the cable processor 265 and / or the sensor 220 to be the source of communication signals and send information via these signals to the device 110. In an implementation, the communication signals 276 conform to a controller area network (CAN) bus protocol using two communication wires 240 a and 240 b that control communicationsAttorney Docket No. Z20886WO-01based on a voltage differential between the two wires (e.g., a CAN-hi and a CAN-lo).

[0205] In an implementation, the data interface circuitry 260 includesan authentication circuit 264 and the cable contacts comprise at least one authentication cable contact 395 e. In such an implementation, the conductive wires include at leastone authentication wire 240 e and the contacts in the port 298 include at leastone authentication contact 399 e. The authentication circuit 264 is configured to receive an authentication / identification (AU / ID) request from the device 110 via the at least one authentication cable contact 395 e. Additionally, the authentication circuit 264 is configured to send AU / ID information back to the device 110 in response to the received AU / ID request.

[0206] FIG. 20 is a schematic diagram 1900 illustrating components of a customizable patient monitoring device. The customizable patient monitoring device includes a controller 2006 (e.g., a micro-controller) , which may be connected, for example by a wireless connection such as Wi-Fi connection 2012 (and / or one or more other or additional wireless networks, and / or a wired connection), to another device or system of devices, which may include, e.g. one or more tablets, medical devices, etc.

[0207] The controller 2006 includes a processor and memory, as well as a number of sensor interfaces (e.g., ports) S1-S8 (in other embodiments, more or less than 8 sensor interfaces may be included), for connection and disconnection of any of a variety of physiological parameter sensors to the customizable patient monitoring device. In the embodiment depicted, the customizable patient monitoring device also includes a non-invasive blood pressure (NIBP) module 2008, including a port or module for connection of a NIBP sensor. However, in some embodiments, an NIBP port or module 2008 may not be included.

[0208] Additionally, as described herein, in some embodiments, one or more ports of the customizable patient monitoring device may be used for connection (or disconnection) of one or more additional such devices. In such instances, the number of sensor interfaces or ports available for the system as a whole may be greater than the number of sensor interfaces or ports of any one such device. Furthermore, in various embodiments, the controller of each of one or of several of such devices may be used in control and processing relating to some or all of the sensor interfaces or ports, or control may be distributed between the devices and / or other devices in the system in various ways.

[0209] The controller 2006 is communicatively connected to components of the customizable patient monitoring device including a rotary encoder 2004 (e.g., rotary dial 206Attorney Docket No. Z20886WO-01as depicted in FIG. 2 herein), the sensor interfaces S1-S8, theNIBP module 2008, and a touch screen 2010. among other components. The controller 2006 may communicate with various sensor interfaces using a communication protocol such as, for example, controller area network flexible data-rate (CAN FD), or a serial protocol. The controller may be used in controlling, analyzing, managing and regulating aspects of operation and interfaces of the customizable patient monitoring device. The controller may, for example, be used in detection (which may include identification) of physiological sensors or other accessories that may be connected to ports or sensor interfaces, processing of signals, such as from connected sensors to obtain physiological parameter information, processing of user input, such as via the touchscreen 2010, providing displays, such as grids of tiles and enhanced displays, managing wireless network access and interface, and may be used in relation to other aspects of operation of a customizable patient monitoring device 2000. Furthermore, in some embodiments, the controller 2006 is also in communicative connection with other devices connected to the customizable patient monitoring device 2000, and may be used in, e.g., managing and controlling aspects of operation thereof, including, for example, the providing of augmented displays on connected devices (e.g. a tablet or medical device), and interfacing and communications of such devices with the customizable patient monitoring device 2000.

[0210] In some embodiments, connected devices with displays, such as may include augmented displays, may include one or more other devices, for example, among other things, display screens or projector displays, such as where the displays of the other device(s) are controlled by a controller of a connected customizable patient monitoring device. Such arrangements may effectively add to the overall display or screen space, such as may be associated with the system including the customizable patient monitoring device, without requiring the other device(s) to include components such as a processor or controller.

[0211] FIG. 21 illustrates an example of components of various devices described with reference to prior figures. The components 2808, 2810, 2812, 2814, 2816, and 2818 are communicatively coupled (directly and / or indirectly) to each other for bi-directional communication. Similarly, the components 2820, 2822, 2824, 2826, and 2828 are communicatively coupled (directly and / or indirectly) to each other for bi-directional communication. As described, in some embodiments, a customizable patient monitoring device may be communicatively coupled with one or more other devices, which may include one or more therapeutic medical devices (e.g., defibrillator, ventilator, etc.).

[0212] In some implementations, the components 2808. 2810, 2816, and / or 2818 of the therapeutic medical device 2802, which may be coupled with a customizable patientAttorney Docket No. Z20886WO-01monitoring device (e.g., patient interface device 2834), may be combined into one or more discrete components and components 2816 and / or 2818 may be part of the processor 2808. The processor 2808 and the memory 2810 may include and / or be coupled to associated circuitry in order to perform the functions described herein. Additionally, the components 2820, 2822, and 2828 of companion device 2804 may be combined into one or more discrete components and component 2828 may be part of the processor 2820. The processor 2820 and the memory 2822 may include and / or be coupled to associated circuitry in order to perform the functions described herein.

[0213] In some implementations, the therapeutic medical device 2802 may include the therapy delivery control module 2818. For example, the therapy delivery control module 2818 may be an electrotherapy delivery circuit that includes one or more high-voltage capacitors configured to store electrical energy for a pacing pulse or a defibrillating pulse. The electrotherapy delivery circuit may further include resistors, additional capacitors, relays and / or switches, electrical bridges such as an H-bridge (e.g., including a plurality of insulated gate bipolar transistors or IGBTs). voltage measuring components, and / or current measuring components. As another example, the therapy delivery control module 2818 may be a compression device electro-mechanical controller configured to control a mechanical compression device. As a further example, the therapy delivery' control module 2818 may be an electro-mechanical controller configured to control drug delivery, temperature management, ventilation, and / or other type of therapy delivery.

[0214] The therapeutic medical device 2802 may incorporate and / or be configured to couple to one or more patient interface devices 2830 and patient interface devices that may be coupled with a patient 2849. The patient interface devices 2830 may include one or more therapy delivery component(s) 2832a and / or one or more sensor(s) 2832b. Similarly, the companion device 2804 may be adapted for medical use and may incorporate and / or be configured to couple to one or more patient interface device(s) 2834. The patient interface device(s) 2834 may include one or more sensors 2836.

[0215] The sensor(s) 2832b and 2836 may include one or more of: sensing electrodes (e.g., the sensing electrodes 2838), ventilation and / or respiration sensors (e.g., the ventilation and / or respiration sensors 2830), temperature sensors (e.g., the temperature sensor 2842), chest compression sensors (e.g., the chest compression sensor 2844), etc. In some implementations, the information obtained from the sensors 2832b and 2836 can be used to generate information displayed at the therapeutic medical device 2802 and simultaneously at the display views at companion device 2804 and described above. In one example, theAttomey Docket No. Z20886WO-01sensing electrodes 2838 may include cardiac sensing electrodes. The cardiac sensing electrodes may be conductive and / or capacitive electrodes configured to measure changes in a patient’s electrophysiology to measure the patient’s ECG information. The sensing electrodes 2838 may further measure the transthoracic impedance and / or a heart rate of the patient. The ventilation and / or respiration sensors 2830 may include spirometry sensors, flow sensors, pressure sensors, oxygen and / or carbon dioxide sensors such as, for example, one or more of pulse oximetry sensors, oxygenation sensors (e.g., muscle oxygenation / pH), 02 gas sensors and capnography sensors, impedance sensors, and combinations thereof. The temperature sensors 2842 may include one or more of an infrared thermometer, a contact thermometer, a remote thermometer, a liquid cry stal thermometer, a thermocouple, a thermistor, etc. and may measure patient temperature internally and / or externally. The chest compression sensor 2844 may include one or more motion sensors including, for example, one or more accelerometers, one or more force sensors, one or more magnetic sensors, one or more velocity' sensors, one or more displacement sensors, etc. The chest compression sensor 2844 may provide one or more signals indicative of the chest motion to the therapeutic medical device 2802 via a wired and / or wireless connection. The chest compression sensor 2844 may be, for example, but not limited to, a compression puck, a smart-phone, a handheld device, a wearable device, etc. The chest compression sensor 2844 may be configured to detect chest motion imparted by a rescuer and / or an automated chest compression device (e.g.. a belt system, a piston system, etc.). The chest compression sensor 2844 may provide signals indicative of chest compression data including displacement data, velocity data, release velocity data, acceleration data, force data, compression rate data, dwell time data, hold time data, blood flow data, blood pressure data, etc. In an implementation, the defibrillation and / or pacing electrodes may include or be configured to couple to the chest compression sensor 2844.

[0216] In various implementations, the sensors 2832b and 2836 may include one or more sensor devices configured to provide sensor data that includes, for example, but not limited to ECG, blood pressure, heart rate, respiration rate, heart sounds, lung sounds, respiration sounds, end tidal CO2, saturation of muscle oxygen (SMO2), oxygen saturation (e.g., SpO2and / or PaO2), cerebral blood flow, point of care laboratory measurements (e.g., lactate, glucose, etc.), temperature, electroencephalogram (EEG) signals, brain oxygen level, tissue pH, tissue fluid levels, images and / or videos via ultrasound, laryngoscopy, and / or other medical imaging techniques, near-infrared spectroscopy, pneumography, cardiography, and / or patient movement. Images and / or videos may be fyvo-dimensional or three-Attorney Docket No. Z20886WO-01dimensional, such a various forms of ultrasound imaging.

[0217] The one or more therapy deliver)’ components 2832a may include one or more of: electrotherapy electrodes (e.g., the electrotherapy electrodes 2838a), ventilation device(s) (e.g., the ventilation devices 2838b), intravenous device(s) (e.g., the intravenous devices 2838c), compression device(s) (e.g., the compression devices 2838d), etc. For example, the electrotherapy electrodes 2838a may include defibrillation electrodes, pacing electrodes, and combinations thereof. The ventilation devices 2838b may include a tube, a mask, an abdominal and / or chest compressor (e g., a belt, a cuirass, etc.), etc. and combinations thereof. The intravenous devices 2838c may include drug delivery’ devices, fluid delivery' devices, and combinations thereof. The compression devices 2838d may include mechanical compression devices such as abdominal compressors, chest compressors, belts, pistons, and combinations thereof. In various implementation, the therapy delivery component(s) 2832a may be configured to provide sensor data and / or be coupled to and / or incorporate sensors. For example, the electrotherapy electrodes 2838a may provide sensor data such as transthoracic impedance, ECG, heart rate, etc. Further the electrotherapy electrodes 2838a may include and or be coupled to a chest compression sensor. As another example, the ventilation devices 2838b may' be coupled to and / or incorporate flow sensors, gas species sensors (e.g., oxygen sensor, carbon dioxide sensor, etc.), etc. As a further example, the intravenous devices 2838c may be coupled to and / or incorporate temperature sensors, flow sensors, blood pressure sensors, etc. As yet another example, the compression devices 2838d may be coupled to and / or incorporate chest compression sensors, patient position sensors, etc. The therapy delivery control modules 2818 may be configured to couple to and control the therapy delivery component(s) 2832a, respectively.

[0218] The one or more sensor(s) 2832b and 2836 and / or the therapy delivery component(s) 2832a may provide sensor data. The patient data provided at the display screens of the therapeutic medical device 2802 and companion device 2804 may display' at least some or all of the sensor data and / or different sensor data. For example, the therapeutic medical device 2802 may process signals received from the sensor(s) 2832b and / or the therapy delivery component(s) 2832a to determine the sensor data. Similarly, the companion device 2804 may' process signals received from the sensor(s) 2836 and / or sensor data from the sensors 2832b received via the therapeutic medical device 2802to determine the sensor data.

[0219] Some embodiments include providing mechanical ventilation in connection with, for example, a patient experiencing respiratory distress. For example, in someAttorney Docket No. Z20886WO-01embodiments, a ventilator or portable ventilator may be communicatively connected to a customizable patient monitoring device. Respirator}’ distress may include, for example, any form of respiratory or breathing difficulty, impairment or problem, including respiratory failure. Respirator}' parameter data can include data relating to respiratory, pulmonary or lung related parameters, as may, for example, be associated with respiratory, pulmonary or lung related characteristics, attributes or functions. Respiratory parameter data can include, for example, one or more of data related to pulmonary associated pressure, flow, volume or capacity related parameters, including parameters that may be measured using one or more flow sensors, pneumotachometers or spirometers. Respirator ' parameter data can include, for example, one or more of data relating to respiratory mechanics, such as respiratory compliance (Crs), respiratory elastance) and respiratory resistance (Rrs). Respiratory parameter data can also include, for example, parameters such as vital capacity (VC), forced vital capacity (FVC), forced expiratory volume (FEV) at timed intervals (e.g., between 0.5 and 10 seconds, less than 0.5 second, 0.5 second, 1.0 second or FEV1, 2.0, 3.0 seconds, 4.0 seconds or 5.0 seconds), forced expiratory flow (FEF) at, e.g., 10%-90% capacity, such as 25%-75% or FEF25-75, peak expiratory flow rate (PEF or PEFR) and maximum breathing capacity (sometimes called maximal voluntary ventilation or MW). Respirator}' parameter data may be presented in various different ways or forms, such as may include, for example, in raw terms, such as liters or liters per second, or as percentages. Respirator}' parameter data may also be presented, for example, as "‘predicted7’ values, such as percent predicted, which can, for example, include results as a percentage value in connection with a reference, average, or other “predicted” value. “Predicted” values may, in some cases, be associated with patients or hypothetical patients of one or more similar characteristics.

[0220] A respiratory status may. for example, relate to, identify, or indicate the presence or absence of, one or more respiratory, pulmonary and / or lung related conditions, and may include respiratory distress. A condition may include a state, disease, or problem, or several thereof, or a type, group or category thereof. A respirator}' status may include an etiology relating to a respiratory condition or a non-respiratory condition (e.g., respiratory distress associated with acute heart failure). A non-respiratory condition may, for example, be associated with one or more non-respiratory systems, e.g., cardiac, endocrine, exocrine, circulator ', immune, lymphatic, nervous, muscular, renal, skeletal, or others. Additionally, a respiratory status may include one or more determined, assessed, estimated, probable or possible conditions, or determined, assessed, probable or possible associated etiologies. A respiratory status may also include data associated any of the foregoing, which may be calledAttorney Docket No. Z20886WO-01respiratory status data.

[0221] Ventilators, such as portable ventilators, and ventilation systems, may include, for example, devices or systems capable of delivering ventilation, whether such delivered ventilation is controlled internally, remotely, or with aspects of both.

[0222] Various ventilation parameter related terms or abbreviations, including fraction of inspired oxygen (FIO2), positive end-expiratory pressure (PEEP) and others, refer to ventilation related settings, even though the word “setting” may or may not be stated. Furthermore, reference to a ventilation parameter, parameter setting, or setting may be used to refer to the parameter in a conceptual or definitional sense, or the value associated with a particular setting. A user may include an individual operating, supervising or in whole or in part responsible for operation of a device such as a portable ventilator, even if, during a particular period of time w hile the device is operating, the user may not be interacting with the device.

[0223] Ventilation related settings may include, for example, any setting, such as a current, selected, set or entered ventilation parameter, parameter value, or other setting relating to ventilation, any aspect of ventilation, operation of a ventilator, such as a portable ventilator, in association with providing or provided ventilation, including mechanical ventilation. Ventilation related settings may include, for example, one or more of settings related to a mode or form of ventilation, power, communication, netw ork connection, remote or internal control, ventilation parameters such as FIO2, PEEP (or baseline airway pressure (BAP)), closed loop control (PCLC), etc., among other things.

[0224] An alert or alarm may be presented for the attention of a user, such as by being visually or audibly presented, such as via a display, graphical user interface (GUI) or speaker of a device. However, an alert or alarm may also include an alert or alarm condition that is algorithmically identified, recognized or determined by a computerized device, and not necessarily presented or displayed. The term optimizing may include, for example, improvement or improved operation in one or more aspects, for example, relative to an actual, potential or hypothetical less optimized situation or less optimized operation. The term adjusting can include changing as well as not changing or maintaining without change, as may be appropriate. A determined parameter value can include a determined estimated or determined approximated value for the parameter. The term monitoring can refer to or include, for example, monitoring or tracking performed by a computerized device utilizing one or more algorithms and not by a person or user, or monitoring by a person or user, or both. The term continuous can include, among other things, on a periodic basis (withAttorney Docket No. Z20886WO-01identical or different periods), on a frequent basis, on a repeated basis, or cyclically, for example.

[0225] In some embodiments, a controller of a ventilator internally signals a mechanical ventilation system (or apparatus) of the ventilator in order to implement control thereof, whether such internal signaling implements internal control or remote control. Internal control includes a controller of a portable ventilator internally signaling the mechanical ventilation system of the portable ventilator to implement control according to a setting value (or more than one setting value) that the controller determines, even if the determined setting value is determined based at least in part on a setting value of a received request / command. Remote control includes the controller of the portable ventilator internally signaling the mechanical ventilation system of the portable ventilator according to a setting value received by the controller via a request / command from a remote control device or system.

[0226] In some embodiments, a ventilator may be capable of either internal or remote control, or operation with aspects of both, and may be capable of determining which, or what particular state or mode, is employed or used at a predetermined or particular time.Furthermore, a portable ventilator may be capable of switching between modes or states of operation, such as may include an internal control mode, a remote control mode, or a mode that includes aspects of both.

[0227] A controller can include physical aspects such as one or more processors and one or more memories, as well as software based aspects, which may include one or more programs, algorithms or software based aspects. The software based aspects may, for example, be stored, in the one or more memories of the controller, accessed by the one or more processors of the controller and used or executed by the processor.

[0228] The term controls may include physical controls, display or GUI based controls, or both. Controls may, for example, allow user interaction with a device or system, such as may affect operation of the device or system, which may include, for example, making selections or providing input to set, select, change, increase, decrease, confirm or override implementation of a parameter setting value or a mode. A device or system with controls may, in various aspects, operate without user interaction, with user interaction, or wi th aspects of both. This may include operation that may proceed, in various aspects or instances, without user interaction, but may permit of, or require, user interaction in some aspects or instances. A display or GUI may include controls, and / or controls may include a display or GUI.Attorney Docket No. Z20886WO-01

[0229] In some embodiments, a set of controls, such as of a particular device, may include one or more respiratory aspects. Respiratory’ aspects of controls may include, for example, display or GUI aspects relating to any aspects of ventilation, ventilation parameters or aspects relating to respiration, respiratory7distress or respiratory parameters.

[0230] Herein, remote control may include control, or aspects of control, provided from outside of, or separately from, a controlled device or system, such as by wired or wireless signaling or communication, such as may include, for example, Bluetooth or ultrawide band. As such, remote control may be implemented via a wired only connection that connects a remote control device and a remotely controlled device, or by a wireless only connection, or by a combination of wired connection and wireless connection, for example. Remote control, such as remote control by a remote control device or system, may include control with or without aspects of user interaction with the remote control device or system, such as, for example, by the user using controls of the remote control device or system. Internal control, such as a device internally controlling itself, may or may not include aspects of user interaction with the internally controlled device, such as, for example, by the user using controls of the internally controlled device. User interaction may include, for example, a user using controls to input, set, select, change, increase, decrease, confirm or override implementation of a parameter setting value or a mode. User interaction may or may not be prompted, guided, or interactively guided, e g., via one or more GUI based prompt messages, alarms or alerts that may relate, for example, to patient parameters or ventilation parameters, such as may relate to ventilator operation, performance or components, such as sensors.

[0231] Any of various ty pes of gas movers / gas flow generators may be used in various embodiments of a (e g. portable) ventilator, including blowers, compressors, compressor-based and turbomachinery’. In some embodiments, centrifugal blowers are included (or used). Herein, an electronic circuit board may include a printed circuit board (PCB) or boards.

[0232] In some embodiments, a ventilator, such as a portable ventilator, is configured for integration with one or more other devices or systems, such as onsite or offsite remote devices, systems or interfaces, aspects of which may or may not be included in various embodiments. For example, in some embodiments, the ventilator may couple, in a wired and / or wireless fashion, with a device such as a patient monitor or critical care monitor (CCM). In some embodiments, for example, a defibrillator / CCM. portable ventilator, or other device, such as another medical device, monitoring device or computing device, may be. include or function as a CCM. Furthermore, in some embodiments, the ventilator may coupleAttorney Docket No. Z20886WO-01with one or more computing systems, computers, computing devices or portable computers, which can include, for example, a cloud-basing computing system, computer, notebook computer, tablet, touch-based device, smartphone, wearable device or implantable device, among other things.

[0233] In some embodiments, smaller size, smaller footprint, lighter weight and / or greater simplicity may be desirable or optimized in a portable ventilator of a hybrid ventilation system. Optimization of a hybrid ventilation system or components thereof, or other devices in the environment thereof, such as a defibrillator / CCM or tablet, may take into account various factors such as the actual, predicted, likely or anticipated setting, context, environment or application, such as may include non-hospital contexts. Optimization may also take into account allocation of roles of various devices in such contexts. Furthermore, the hybrid ventilation system or components thereof may be optimized for users with limited training or experience. Still further, the hybrid ventilation system or components thereof may be optimized for use in environments that may include other integrated devices or systems.

[0234] In some embodiments, a ventilator, such as a portable ventilator, of a hybrid ventilation system may be capable of obtaining patient respiratory parameter data, which can be used in determining a respiratory status of the patient, and may be used in determining a disease state of etiology of the patient, and also in determining appropriate patient treatment. In various embodiments, such determinations may be made, for example, by the portable ventilator itself or by another device to which the portable ventilator sends data, such as respiratory parameter or respiratory status data. This capability of the portable ventilator may be especially advantageous in various non-hospital and crisis settings, in which availability of other devices may be limited or unpredictable.

[0235] Furthermore, in some embodiments, a portable ventilator of a hybrid ventilation system may be capable of either internal control, remote control, or both. In some embodiments, this, in turn, may allow use of a portable ventilator that has less internal controls and / or is smaller or lighter, which can also be especially advantageous in various non-hospital and crisis settings.

[0236] For example, the space immediately surrounding a critical care patient can be very crowded with equipment or items such as, for example, hoses, tubes, wires and various devices. It can be beneficial or advantageous to minimize, for example, the spatial impact of a ventilator. In some embodiments, for example, a portable ventilator may provide advantages by allowing modularization of, or allowing a higher degree of modularization of. a system including a ventilator, which may allow for a much smaller, simpler ventilator close to theAttorney Docket No. Z20886WO-01patient. Furthermore, in some embodiments, the controls in or of a remote control device or system may be some variable distance from the patient (e.g. between 0-3 feet, between 3-6 feet, between 6-9 feet, between 9-12 feet, further than 12 feet, or offsite). Some embodiments provide benefits or advantages to patient care by, for example, simplifying the immediate clinical environment of the patient. For example, in some embodiments, even if the combined weight and / or size of a combination of a ventilator and different remote control device, together, are the same or similar to a system in which the controls are provided in or with the ventilator, the combination of the ventilator and the different remote control device may be more usable, or more practically or optimally useable, in various clinical contexts, for example, since only a relatively small ventilator may be required to be at the patient's side or very close to the patient. Some embodiments provide a portable ventilator, of a hybrid ventilation system, that provides these advantages.

[0237] In some embodiments, an overall environment may include a portable ventilator or hybrid ventilation system that may couple and operationally integrate with one or more other devices, each of which may provide certain roles or functionality in the overall environment. These roles may relate to, for example, device and patient related sensing, operation, processing, software, algorithms, applications, data storage, communication, integration (of devices and systems, roles, functions, and physical, software based and conceptual components and aspects), user interaction and guidance, and patient related assessments or interventions. Within the integrated environment, roles of each device may be optimized, taking into account, for example, factors relating to each device or system as well as the overall environment and anticipated settings. Such optimization may also take into account factors relating to the need for the hybrid ventilation system or components thereof to be of a particular or sufficiently small size, light weight, and / or degree of simplicity or ease of portability or use. In some embodiments, a hybrid ventilation system augments the ability to accurately assess or screen a patient’s condition, to determine or select, and initiate and deliver, an effective intervention, and / or to ongoingly control or adjust, or assist in control and adjustment of, parameters relating to an applied intervention. Furthermore, this augmentation may be optimized in view of the overall environment, available devices, systems or users at a given time or time period, and available communication between them at a given time or time period, as well as changing aspects thereof over time.

[0238] In some embodiments, for example, one or more devices or systems coupled with a portable ventilator, or integrated into the environment thereof, may supply, or partially supply, components or other aspects that may augment or enhance the operation of theAttorney Docket No. Z20886WO-01portable ventilator, and / or otherwise might be, or need to be, included with or in the portable ventilator. Some such aspects may include physiological and operational signaling, sensing or measuring aspects. Other aspects may relate to power, communication, device recognition, authentication or coupling. Other aspects may relate to processing, hardware and software, such as for data processing and management, data and device integration, or operational aspects such as patient oxygenation or other ventilation related parameters or settings. Other aspects may related to patient respiratory or status assessment, diagnostic screening, diagnosis, treatment or intervention (which may include, e g., manual treatments, treatments using medical devices, administration of drugs, etc.). Other aspects may include controls and control relating to the portable ventilator (physical, display or GUI based, or both), as well as features thereof.

[0239] In some embodiments, a portable ventilator may have a set of (one or more) included controls, while one or more remote control devices, systems or monitors may also have a set of (one or more) remote controls relating to the portable ventilator. A set of remote controls may for allow remote control of the portable ventilator, such as may relate, for example, to aspects of operation of a mechanical ventilation system of the portable ventilator. In various embodiments, a set of included controls of portable ventilator may vary across a spectrum of possibilities.

[0240] In various embodiments, a set of remote controls may include respiratory aspects that are separate from other aspects, or may include respiratory aspects that are mixed, combined or integrated, for example, into a larger display or GUI or set of controls that may include non-respiratory aspects as well. Furthermore, in various embodiments, a set of remote controls may be separate or separable from other aspects of controls, or may be integrated with other aspects. In some embodiments, the portable ventilator may have no included controls at all, or may have a limited set of included controls. For example, any or many controls relating to the portable ventilator may be provided by one or more sets of remote controls of one or more other devices, systems or monitors. In some embodiments, a set of remote controls, or a portion thereof, may, in whole or in part, correspond to, emulate, mirror, duplicate, replicate, simulate, or be in any of varying degrees similar to a set of included controls of the portable ventilator. Furthermore, in some cases in which the portable ventilator has no controls or a limited set of controls, a set of remote controls may, to some degree, be similar to or replicate a hypothetical set of included controls that might be included in a portable ventilator.

[0241] The description set forth herein in connection with the appended drawings isAttorney Docket No. Z20886WO-01intended to be a description of various, illustrative embodiments of the disclosed subject matter. Specific features and functionalities are described in connection with each illustrative embodiment; however, it will be apparent to those skilled in the art that the disclosed embodiments may be practiced without each of those specific features and functionalities.

[0242] Reference throughout the specification to “one embodiment” or “an embodiment” means that a particular feature, structure, or characteristic described in connection with an embodiment is included in at least one embodiment of the subject matter disclosed. Thus, the appearance of the phrases “in one embodiment” or “in an embodiment” in various places throughout the specification is not necessarily referring to the same embodiment. Further, the particular features, structures or characteristics may be combined in any suitable manner in one or more embodiments. Further, it is intended that embodiments of the disclosed subject matter cover modifications and variations thereof.

[0243] As used in the specification and the appended claims, the singular forms “a,” “an,” and “the” include plural referents unless the context expressly dictates otherwise. That is, unless expressly specified otherwise, as used herein the words “a,” “an,” “the.” and the like carry the meaning of “one or more.” Additionally, it is to be understood that terms such as “left,” “right,” “top,” “bottom,” “front,” “rear,” “side,” “height,” “length,” “width,” “upper,” “low er,” “interior,” “exterior,” “inner,” “outer,” and the like that may be used herein merely describe points of reference and do not necessarily limit embodiments of the present disclosure to any particular orientation or configuration. Furthermore, terms such as “first.” “second,” “third,” etc., merely identify one of a number of portions, components, steps, operations, functions, and / or points of reference as disclosed herein, and likewise do not necessarily limit embodiments of the present disclosure to any particular configuration or orientation.

[0244] Furthermore, the terms “approximately,” “substantially”, “about,” “proximate,” “minor variation,” and similar terms generally refer to ranges that include the identified value within a margin of 20%, 10%, 5%, or less than 5%, and any values therebetween.

[0245] All of the functionalities described in connection with one embodiment are intended to be applicable to the additional embodiments described below except where expressly stated or where the feature or function is incompatible with the additional embodiments. For example, where a given feature or function is expressly described in connection with one embodiment but not expressly mentioned in connection with an alternative embodiment, it should be understood that the inventors intend that that feature orAttorney Docket No. Z20886WO-01function may be deployed, utilized or implemented in connection with the alternative embodiment unless the feature or function is incompatible with the alternative embodiment.

[0246] In some instances, variations of a term may be utilized that may refer to the same or similar concepts, and certain terms may have meanings that are informed by a particular context. Generally, sending, receiving, or transmitting of data may include by wired and / or wireless connection, and / or within one or more wired or wireless networks. Furthermore, sending from a first entity to a second entity, or to be received by the second entity, can include sending from the first entity to the second entity, or to be received by the second entity, directly from the first entity' to the second entity, or indirectly via one or more intermediary entities.

[0247] While certain embodiments have been described, these embodiments have been presented by way of example only and are not intended to limit the scope of the present disclosures. Indeed, the novel methods, apparatuses and systems described herein can be embodied in a variety of other forms; furthermore, various omissions, substitutions and changes in the form of the methods, apparatuses and systems described herein can be made without departing from the spirit of the present disclosures. The accompanying claims and their equivalents are intended to cover such forms or modifications as would fall within the scope and spirit of the present disclosures.

Claims

Attorney Docket No. Z20886WO-01WHAT IS CLAIMED IS:

1. A medical monitoring device for monitoring of a patient during treatment of the patient, comprising:a monitoring device display;a plurality' of dynamically configurable ports, each configured to allow connection of any of a plurality of connectable physiological sensors, and each configured to allow connection of a physiological sensor of a plurality of physiological sensors connected to the medical monitoring device for monitoring of the patient,the medical monitoring device configured such that each of the plurality of physiological sensors is selectable by a user of the medical monitoring device at least in part by connection, to some or all of the plurality’ of dynamically configurable ports, of each of the plurality of physiological sensors;at least one processor and at least one memory', the at least one memory' comprising a monitoring director configured to be executable by the at least one processor in:receiving signals from each of the plurality of physiological sensors, processing the received signals to obtain, for each of the plurality of physiological sensors, clinically presentable physiological information comprising a specific physiological parameter and a magnitude for the specific physiological parameter, comprising:if the information is accessible from the received signals, accessing the information from the received signals, andif the information is not accessible from the received signals, computing the information based at least in part on the received signals,displaying, on the monitoring device display, an arrangement of display units, each occupying a portion of an area of the monitoring device display, each configured to be associated with a specific physiological sensor of the plurality' of physiological sensors, and each configured to display the information associated with the specific physiological sensor, andupon actuation relating to a first display unit of the arrangement of display units, cause display, on the monitoring device display, of a first enhanced display associated with the first display unit, the first enhanced display replacing at least some of the display units of the arrangement of display units, and the first enhanced display displaying additional information associated with the specific physiological parameter associated with the first display unit, the additional information being in addition to the information displayed by theAttorney Docket No. Z20886WO-01first display unit.

2. The medical monitoring device of claim 36, wherein the plurality of connectable physiological sensors comprises physiological sensors for enabling measurement of non-invasive blood pressure (NIBP), systolic blood pressure, diastolic blood pressure, mean arterial pressure (MAP), invasive blood pressure (IBP), pulse rate (PR), pulse pressure variation (PPV), respiratory rate (RR). end-tidal carbon dioxide (EtCO2), capnogram waveform, oxygen saturation (SpO2), photoplethysmography (PPG) waveform, a hypovolemia compensation measurement, inspiratory7volume (Vi), expiratory volume (Ve), peak inspiratory pressure (PIP), temperature, heart rate (HR), ECG waveform, heart rate variability (HRV), and amplitude spectrum area (AMSA).

3. The medical monitoring device of claim 1, wherein the plurality of connectable phy siological sensors comprises a non-invasive blood pressure (NIBP) sensor, an invasive blood pressure (IBP) sensor, a capnograph, a pulse oximeter, a sensor that senses flow rate, a sensor that senses pressure, a temperature sensor, and one or more electrodes.

4. The medical monitoring device of claim 1, comprising at least one of: accessing and computing the information from anon-invasive blood pressure (NIBP) sensor.

5. The medical monitoring device of claim 4, wherein the accessed information comprises at least one of: systolic blood pressure, diastolic blood pressure, and mean arterial pressure (MAP).

6. The medical monitoring device of claim 4, wherein the computed information comprises mean arterial pressure (MAP).

7. The medical monitoring device of claim 1, comprising at least one of: accessing and computing the information from the received signals from an invasive blood pressure (IBP) sensor.

8. The medical monitoring device of claim 7, wherein the accessed information comprises at least one of: systolic blood pressure, diastolic blood pressure, and mean arterial pressure (MAP).Attorney Docket No. Z20886WO-019. The medical monitoring device of claim 7. wherein the computed information comprises at least one of mean arterial pressure (MAP), pulse pressure variation (PPV), respiratory rate (RR), and pulse rate (PR).

10. The medical monitoring device of claim 1, comprising at least one of: accessing and computing the information from the received signals from a capnograph.

11. The medical monitoring device of claim 10, wherein the accessed information comprises end tidal carbon dioxide (EtCO2).

12. The medical monitoring device of claim 10, wherein the computed information comprises a capnogram waveform.

13. The medical monitoring device of claim 1, comprising at least one of: accessing and computing the information from the received signals from a pulse oximeter.

14. The medical monitoring device of claim 13, wherein the accessed information comprises at least one of: oxygen saturation (SpO2), and a photoplethysmography (PPG) waveform.

15. The medical monitoring device of claim 13, wherein the computed information comprises at least one of: a photoplethysmography (PPG) waveform, pulse rate (PR), pulse pressure variation (PPV), a hypovolemia compensation measurement, and respiratory' rate (RR)16. The medical monitoring device of claim 1, comprising at least one of: accessing and computing the information from the received signals from a sensor that senses flow' rate.

17. The medical monitoring device of claim 16, wherein the accessed information comprises respiratory rate (RR).

18. The medical monitoring device of claim 16, wherein the computed information comprises at least one of: inspiratory’ volume and expiratory’ volume.Attorney Docket No. Z20886WO-0119. The medical monitoring device of claim 1, comprising at least one of: accessing and computing the information from the received signals from a sensor that senses pressure.

20. The medical monitoring device of claim 16, wherein the computed information comprises peak inspiratory pressure (PIP).

21. The medical monitoring device of claim 1, comprising at least one of: accessing and computing the information from the received signals from a temperature sensor.

22. The medical monitoring device of claim 21, wherein the accessed information comprises temperature.

23. The medical monitoring device of claim 1, comprising at least one of: accessing and computing the information from the received signals from one or more electrodes.

24. The medical monitoring device of claim 21, wherein the accessed information comprises at least one of: an ECG waveform and heart rate (HR).

25. The medical monitoring device of claim 21, wherein the computed information comprises at least one of: an ECG waveform, heart rate (HR), respiratory rate (RR), heart rate variability (HRV), and amplitude spectrum area (AMSA).

26. The medical monitoring device of claim 21, wherein computing the information based in part on the received signals comprises computing the information based on information obtained using the received signals.

27. The medical monitoring device of claim 1, wherein accessing the information comprises use of the monitoring director in applying at least one communication protocol in associating at least a portion of the received signals with the information.

28. The medical monitoring device of claim 1, wherein computing the information comprises use of the monitoring director in applying software stored in the at least one memory to obtain the information.Attorney Docket No. Z20886WO-0129. The medical monitoring device of claim 28, wherein computing the information comprises use of the monitoring director in applying at least one software based library stored in the at least one memory to obtain the information using information accessed by the monitoring director.

30. The medical monitoring device of claim 29, wherein the at least one software library is loaded into the at least one memory from, and upon connection of, a physiological sensor of the plurality of physiological sensors to a port of the plurality of dynamically configurable ports.

31. The medical monitoring device of claim 28, wherein computing the information comprises use of the monitoring director in applying the software stored in the at least one memory to obtain the information using information accessed by the monitoring director, and comprises use of the received signals.

32. The medical monitoring device of claim 28, wherein computing the information comprises use of the monitoring director in applying the software stored in the at least one memory to obtain the information using information accessed by the monitoring director, without use of the received signals.

33. The medical monitoring device of claim 1, wherein displaying, on the monitoring device display, the arrangement of display units comprises use of the monitoring director in applying software stored in the at least one memory.

34. The medical monitoring device of claim 1, wherein the plurality of dynamically configurable ports comprises at least one of: a CAN FD port, a data interface (DI) port, a sensor agnostic data interface (DI) port, a serial port, a smart port, a USB port, a micro-USB port, a USB-C port.

35. The medical monitoring device of claim 1, wherein the plurality of dynamically configurable ports is made of up data interface (DI) ports.

36. The medical monitoring device of claim 1, wherein the plurality of dynamically configurable ports comprising a non-invasive blood pressure (NIBP) port.Attorney Docket No. Z20886WO-0137. The medical monitoring device of claim 1, wherein selection of the plurality of physiological sensors permits minimization of total size and weight of the medical monitoring device and connected physiological sensors.

38. The medical monitoring device of claim 1, comprising a non-removable battery.

39. The medical monitoring device of claim 1, wherein the monitoring device display permits touch-based selection and actuation.

40. The medical monitoring device of claim 1, comprising a physical dial allowing user selection and actuation on the medical monitoring device.

41. The medical monitoring device of claim 1, wherein a volume of the medical monitoring device is no greater than 1,200 cubic centimeters.

42. The medical monitoring device of claim 1, wherein a volume of the medical monitoring device is no greater than 1,000 cubic centimeters.

43. The medical monitoring device of claim 1, wherein a volume of the medical monitoring device is no greater than 820 cubic centimeters.

44. The medical monitoring device of claim 1, wherein a volume of the medical monitoring device is no greater than 2 kilograms.

45. The medical monitoring device of claim 1, wherein a volume of the medical monitoring device is no greater than 1.8 kilograms.

46. The medical monitoring device of claim 1, wherein a volume of the medical monitoring device is no greater than 1.6 kilograms.

47. The medical monitoring device of claim 1, wherein the plurality of dynamically configurable ports is made of 9-12 ports.Attorney Docket No. Z20886WO-0148. The medical monitoring device of claim 1. wherein the plurality of dynamically configurable ports is made of 6-8 ports.

49. The medical monitoring device of claim 1, wherein the lurality of dynamically configurable ports is made of 2-5 ports.

50. The medical monitoring device of claim 1, configured to be powered by batten’ or connect to and powered by an AC power source.

51. The medical monitoring device of claim 50, configured to be powered by the AC power source using a USB-C port of the medical monitoring device.

52. The medical monitoring device of claim 1, comprising a plurality of illuminable indicators, comprising an illuminable indicator associated with each of at least some of the plurality of dynamically configurable ports, each of the illuminable indicators of the plurality of illuminable indicators configured to be illuminated when a physiological sensor is connected to the port associated with the illuminable indicator and configured to be nonilluminated when no physiological sensor is connected to the port associated with the illuminable indicator.

53. The medical monitoring device of claim 52, wherein each of the illuminable indicators of the plurality of illuminable indicators is configured to flash at least upon at least one of: connection and disconnection of the physiological sensor to the port.

54. The medical monitoring device of claim 52, wherein each of the illuminable indicators of the plurality of illuminable indicators comprises at least one of: a light-emitting diode (LED) display, an active-matrix organic light-emitting diode (AMOLED) display, and a organic light-emitting diode (OLED) display.

55. The medical monitoring device of claim 1, comprising at least one micro-controller.

56. The medical monitoring device of claim 1, wherein each of the plurality of user configurable ports is further configured to allow connection of a connectable device other than a physiological sensor.Attorney Docket No. Z20886WO-0157. The medical monitoring device of claim 56, wherein the connectable device comprises at least one of: a medical monitoring device, a ventilator, a defibrillator, a public access automated external defibrillator, a patient monitor, a critical care monitor (CCM) and an infusion pump device.

58. The medical monitoring device of claim 56, wherein the connectable device comprises a display device that does not include a processor.

59. The medical monitoring device of claim 58, wherein the display device that does not comprise a processor comprises at least one of a display screen and a projector.

60. The medical monitoring device of claim 57, wherein the connectable device comprises a second medical monitoring device, and wherein the arrangement of display units comprises at least one display unit associated with a physiological sensor of the plurality of physiological sensors connected to the medical monitoring device and at least one display unit associated with a physiological sensor connected to the second medical monitoring device.

61. A medical monitoring device for monitoring of a patient during treatment of the patient, comprising:a monitoring device display;a plurality of dynamically configurable ports, each configured to allow connection of any of a plurality of connectable physiological sensors, and each configured to allow connection of a physiological sensor of a plurality' of physiological sensors connected to the medical monitoring device for monitoring of the patient,the medical monitoring device configured such that each of the plurality of physiological sensors is selectable by a user of the medical monitoring device at least in part by connection, to some or all of the plurality' of dynamically configurable ports, of each of the plurality' of physiological sensors;at least one processor and at least one memory, the at least one memory comprising a monitoring director configured to be executable by the at least one processor in:receiving signals from each of the plurality’ of physiological sensors, processing the received signals to obtain, for each of the plurality7of physiological sensors, clinically presentable physiological information comprising a specificAttorney Docket No. Z20886WO-01physiological parameter and a magnitude for the specific physiological parameter,displaying, on the monitoring device display, an arrangement of display units, each occupying a portion of an area of the monitoring device display, each configured to be associated with a specific physiological sensor of the plurality of physiological sensors, and each configured to display the information associated with the specific physiological sensor, andupon actuation relating to a first display unit of the arrangement of display units, cause display, on the monitoring device display, of a first enhanced display associated with the first display unit, the first enhanced display replacing at least some of the display units of the arrangement of display units, and the first enhanced display displaying additional information associated with the specific physiological parameter associated with the first display unit, the additional information being in addition to the information displayed by the first display unit, andupon actuation relating to the first enhanced display, cause display, on a display of a computing device communicatively connected with the medical monitoring device, of a first augmented display displaying further information associated with the specific physiological parameter associated w ith the first display unit.

62. The medical monitoring device of claim 61, configured such that the plurality of physiological sensors is identified based on connection by a user of each of the physiological sensors of the plurality of physiological sensors to some or all of the plurality’ of dynamically configurable ports, wherein the plurality of physiological sensors is made up of physiological sensors connected to the medical monitoring device.

63. The medical monitoring device of claim 61, configured such that modification of the plurality of physiological sensors for monitoring of the patient can be accomplished by: disconnection of a first physiological sensor of the plurality to remove the first physiological sensor from the plurality, orconnection of an additional physiological sensor to add the additional physiological sensor to the plurality.

64. The medical monitoring device of claim 61, wherein modification of the plurality of physiological sensors allows customization based on a currently applied level of clinical care to the patient during a course of monitoring and treatment of the patient.Attorney Docket No. Z20886WO-0165. The medical monitoring device of claim 61, wherein modification of the plurality of physiological sensors permits customization based on a level of expertise or training of a user of the medical monitoring device.

66. The medical monitoring device of claim 61, wherein modification of the plurality of physiological sensors permits customization based on environmental conditions.

67. The medical monitoring device of claim 61, wherein the monitoring device display is configured such that the first enhanced display replaces the arrangement of display units.

68. The medical monitoring device of claim 61, wherein at least one of the display units is customizable to display information associated with more than one connected sensing device.

69. The medical monitoring device of claim 61, wherein at least one of the display units is customizable to display information associated with a selected physiological parameter, the selected physiological parameter being selectable from among multiple physiological parameters available for display by the at least one of the display units.

70. The medical monitoring device of claim 61, wherein at least one of the display units is customizable to display information associated with at least two selected physiological parameters.

71. The medical monitoring device of claim 61 , wherein at least one of the display units is customizable to display information associated with at least two physiological sensors.

72. The medical monitoring device of claim 61, wherein the arrangement of display units is configured to be scrollable by a user.

73. The medical monitoring device of claim 61, wherein the augmented display is configured to be scrollable by a user.

74. The medical monitoring device of claim 61, wherein the arrangement of display units comprises a grid of display units.Attorney Docket No. Z20886WO-0175. The medical monitoring device of claim 74, wherein the grid of display units comprises a grid of tiles.

76. The medical monitoring device of claim 61, wherein each of the display units automatically displays the information associated with the specific physiological sensor of the plurality of physiological sensors upon attachment of the specific physiological sensor to the medical monitoring device.

77. The medical monitoring device of claim 61, wherein at least one of the display units displays a trend arrow indicating a trend associated with a physiological parameter associated with the specific physiological sensor associated with the at least one of the display units.

78. The medical monitoring device of claim 77, wherein each of the display units has a rectangular shape.

79. The medical monitoring device of claim 61, wherein the actuation relating to the first display unit is touch-based.

80. The medical monitoring device of claim 61, wherein each of the display units displays at least one of: an alarm threshold, an early warning score (EWS) and a sensor related alarm.

81. The medical monitoring device of claim 61, wherein the arrangement of display units is customizable by a user of the medical monitoring device, and wherein customization of the arrangement of display units comprises selection of locations on the monitoring device display of display units of the arrangement of display units.

82. The medical monitoring device of claim 1, wherein the first enhanced display comprises at least one trend plot associated with the specific physiological parameter associated with the first display unit.

83. The medical monitoring device of claim 1, wherein the first enhanced display is customizable by a user of the medical monitoring device, and wherein customization of the first enhanced display comprises selection of at least a portion of the additional information associated with the specific physiological parameter associated with the first display unit.Attorney Docket No. Z20886WO-0184. The medical monitoring device of claim 61, wherein the first augmented display is customizable by a user of the medical monitoring device, and wherein customization of the first augmented display comprises selection of at least a portion of the further information associated with the specific physiological parameter associated with the first display unit.

85. The medical monitoring device of claim 61, configured such that the further information displayed on the computing device is in addition to the information displayed by the first display unit and in addition to the addition to the additional information displayed by the first enhanced display.

86. The medical monitoring device of claim 61, configured to store chronologically ordered information relating to the monitoring of the patient.

87. The medical monitoring device of claim 61, wherein the first augmented display comprises at least one displayed waveform associated with the specific physiological parameter.

88. The medical monitoring device of claim 61, wherein the first augmented display comprises early warning score (EWS) information.

89. The medical monitoring device of claim 88, wherein the early warning score (EWS) information comprises at least one of: Los Angeles Motor Scale (LAMS) information, Modified Early Warning Score (MEWS) information, sequential organ failure (SOFA) information, and quick sequential organ failure assessment (qSOFA) information, Glasgow coma scale (GCS) information, and shock decision guidance score information.

90. The medical monitoring device of claim 61, wherein the first augmented display comprises clinical decision support information.

91. The medical monitoring device of claim 61, w herein the first augmented display comprises electrode placement guidance.

92. The medical monitoring device of claim 61, wherein the computing device comprises at least one of: a portable computing device, a patient monitoring device and a medicalAttorney Docket No. Z20886WO-01device.

93. The medical monitoring device of claim 61, wherein the computing device comprises a tablet.

94. The medical monitoring device of claim 61, wherein the computing device comprises at least one of: a patient monitoring device, a ventilator, a defibrillator, a public access automated external defibrillator, a patient monitor, a critical care monitor (CCM) and an infusion pump device.

95. The medical monitoring device of claim 61, wherein the plurality of connectable physiological sensors comprises physiological sensors for enabling measurement of non-invasive blood pressure (NIBP), systolic blood pressure, diastolic blood pressure, mean arterial pressure (MAP), invasive blood pressure (IBP), pulse rate (PR), pulse pressure variation (PPV), respiratory rate (RR). end-tidal carbon dioxide (EtCO2), capnogram waveform, oxygen saturation (SpO2), photoplethysmography (PPG) waveform, a hypovolemia compensation measurement, inspiratory volume (Vi), expiratory volume (Ve), peak inspiratory pressure (PIP), temperature, heart rate (HR), ECG waveform, heart rate variability (HRV), and amplitude spectrum area (AMSA).

96. The medical monitoring device of claim 61 , wherein the plurality of connectable physiological sensors comprises a non-invasive blood pressure (NIBP) sensor, an invasive blood pressure (IBP) sensor, a capnograph, a pulse oximeter, a sensor that senses flow rate, a sensor that senses pressure, a temperature sensor, and one or more electrodes.

97. The medical monitoring device of claim 61, configured such that the computing device is communicatively connectable by wired or wireless connection.

98. The medical monitoring device of claim 61, wherein each of the physiological parameters and the magnitude of each of the physiological parameters are updated at a frequency selected by a user of the medical monitoring device.

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