10results about How to "Easy to inactivate" patented technology

The invention discloses a preparation method of a piezoelectric self-sterilization cotton fabric-based pressure sensor. The preparation method specifically comprises the following steps: step 1, preparing a modified boron nitride nanosheet; step 2, preparing a modified boron nitride nanosheet / Ag-MOF545 composite material; step 3, preparing a modified boron nitride nanosheet / Ag-MOF545 cotton fabric based piezoelectric material; and 4, preparing the self-sterilization cotton fabric based piezoelectric pressure sensor. According to the piezoelectric self-sterilization cotton fabric-based pressure sensor, on the basis of a piezoelectric polarization effect generated by a piezoelectric material, a stimulation signal of external strain is converted into a piezoelectric current signal to be output, and molecular electrolysis is generated on the surfaces of bacterial cells by utilizing the current signal; meanwhile, the electroporation effect generated by the current can destroy the integrity of a bacterial membrane and induce metabolism disorder of bacteria, and as a physical method, due to the fact that no additional antibacterial material needs to be loaded and the broad-spectrum antibacterial effect is achieved, the bacteria can be thoroughly killed while the drug resistance of the bacteria is effectively avoided.

Described herein are Zika virus vaccines and compositions and methods of producing and administering said vaccines to subjects in need thereof.

The invention relates to the technical field of chemical catalysts, and provides an application of a CoNi / C composite material in a chlorofluoroalkane dehydrochlorination reaction, and a preparation method of the CoNi / C composite material comprises the step of contacting a cobalt source, a nickel source and a carbon source to obtain the CoNi / C composite material. The CoNi / C composite material can be used as a catalyst for a dehydrochlorination reaction of chlorofluoroalkanes, so that the problem that the catalyst is inactivated due to the phenomena of carbon deposition and easy sintering of the existing catalyst is solved.

The invention relates to the technical field of food biology, in particular to a method for predicting the activity of amylase subjected to an inactivation process or inactivated amylase. The invention provides a method for predicting an inactivation process based on required amylase activity, which comprises the following steps: providing the required amylase activity, presetting an inactivation temperature, and calculating the inactivation time by adopting an amylase activity-inactivation time prediction model according to the required amylase activity. The invention also provides a method for predicting the activity of the inactivated amylase based on the inactivation process, which comprises the following steps: providing the inactivation temperature and the inactivation time, and calculating the activity of the inactivated amylase by adopting the amylase activity-inactivation time prediction model according to the inactivation temperature and the inactivation time. The method disclosed by the invention has relatively good predictive capacity, and is beneficial to accurately controlling the inactivation process conditions; by optimizing the inactivation process, the production time and cost can be reduced, and the production efficiency is improved; the enzyme activity is strictly controlled or the enzyme is inactivated, so that the food quality safety is ensured.

The invention provides an HIV-1 (human immunodeficiency virus-1) nano antibody as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The antibody is expressed by fusing a His tag at the C terminal of a candidate amino acid sequence. The preparation method of the antibody comprises the following steps: immunizing alpaca for multiple times by using a purified antigen cov-NHR VQ capable of simulating an HIV-1gp41NHR tripolymer; peripheral blood of the immunized alpaca is obtained; an intermediate product to be screened is obtained; screening the intermediate product to be screened to obtain a candidate amino acid sequence of the HIV-1 nano antibody; the VHH gene of the candidate amino acid sequence of the antibody is cloned into a prokaryotic expression vector, and nano antibody protein is expressed in the form of VHH-his to obtain the antibody. The antibody can be applied to a modified antibody in a CDR region and preparation of a drug HIV-1 detection reagent for preventing and / or treating HIV-1. The antibody has high specificity and high affinity in a targeted gp41NHR trimer conserved region.

The present invention provides a method for treating antibiotic resistant bacteria (ARB) and antibiotic resistant genes (ARGs) in wastewater. The present invention adopts nano zero-valent iron (nZVI), chlorite (ClO2 ‑ ) and oxygen ternary reaction system, where ClO2 ‑ Oxidation of nZVI to high-valent iron (Fe IV =O), nZVI reduces O2 to generate superoxide anion (·O2 ‑ ), Fe IV =O can effectively destroy the cell membrane structure of ARB, resulting in extracellular O2 ‑ , iron ions, etc. enter the cell, inducing intracellular oxidative stress and damage, leading to ARB inactivation; at the same time, intracellular ARGs leak out of the cell and are oxidized by ·O2 ‑ The attack is rapid and the degradation is rapid. The two active species work together effectively to quickly kill ARB and ARGs. The treatment method of the present invention has a better disinfecting effect on ARB than active chlorine and the common zero-valent iron-activated peroxide Fenton reaction, and has a wide pH application range.

The present invention provides a method for extracting a mycobacterium genome, and belongs to the field of biological detection technology. The method for extracting the mycobacterium genome provided by the present invention uses lysase LysA and LysB for wall breaking treatment, which solves the problem of poor mycobacterium genome extraction effect in the prior art. The total genome amount of Mycobacterium tuberculosis extracted by the present invention can reach about 5-10 times that of the traditional classical CTAB genome extraction method, and the integrity of the obtained genome fragments is significantly improved. Compared with the use of lysozyme overnight treatment in the traditional CTAB genome extraction method, the LysA and LysB treatment in the present invention for 2 hours can achieve several times the extraction efficiency, greatly shortening the extraction time, being superior to the traditional CTAB genome extraction method and the genome extraction kit on the market, and being conducive to the rapid and efficient extraction of complete mycobacterium genomes in clinical and laboratory settings.

The utility model discloses a multifunctional air purifier, which belongs to the field of air purification equipment and is used for solving the problem that the existing air purifier is difficult to purify various air pollutants at the same time, the multifunctional air purifier comprises a case, an air purification device, a humidification device and a heating device, an air outlet hole and an air inlet hole which are communicated with the cavity are formed; the air purification device comprises an exhaust fan, a filter screen, a graphene catalyst layer and a graphene activated carbon layer, the filter screen, the graphene catalyst layer and the graphene activated carbon layer are arranged in the cavity, and the exhaust fan is arranged towards the air outlet; the humidifying device is arranged in the case, and the humidifying device is used for generating water mist and conveying the water mist to the outside of the case; the heating device is arranged in the case and used for increasing the temperature of the chamber and the temperature of the external environment of the case. The multifunctional air purifier can effectively purify various air pollutants such as particulate matters, organic pollutants, peculiar smell, formaldehyde and methylbenzene at the same time, and the air purification effect is improved.