Compliance and leakage amount determination method and device, equipment and storage medium

Abstract

Embodiments of the present application disclose a compliance and leakage determination method and device, equipment and a storage medium, the method is applied to a breathing assistance system including at least a gas flow pipeline provided with an inhalation valve, the method comprises: obtaining real-time flow rate flowing through the inhalation valve and simulation breathing data, the simulation breathing data includes inhalation data and exhalation data; the inhalation data includes inhalation start time and inhalation end time, and the exhalation data includes exhalation start time and exhalation end time; determining pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inhalation start time, the inhalation end time, the exhalation start time and the exhalation end time; and determining system leakage of the breathing assistance system by using the exhalation start time and the inhalation start time. Through the above manner, the self-checking of the leakage and compliance of the breathing assistance system can be realized without using high-precision flow sensors and flow control valves, and the cost is effectively reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of parameter measurement, in particular to a compliance and leakage determination method and device, equipment and storage medium. BACKGROUND

[0002] The traditional leakage detection method of the medical equipment for assisted breathing such as an anesthesia machine or a breathing machine first provides a certain flow rate by a gas source device, adjusts the flow rate so that the airway pressure can be constant at 30 cmH2O, and measures the size of the gas flow rate at this time by a special instrument. The flow rate is the leakage. The determination of lung expansion is called compliance, and the elastic characteristics of the breathing machine can also be represented by the compliance. The compliance is the change value of the unit pressure content, and the calculation formula is C=AVml / ΔPcmH2O. The unit of compliance is ml / cmH2O. The compliance can be divided into dynamic compliance and static compliance. The static compliance refers to the change of the unit pressure content when the pressure in the breathing machine reaches equilibrium at the end of expiration or inspiration. The dynamic compliance refers to the change of the unit pressure content during inspiration or inspiration. The dynamic compliance is affected by the airway resistance.

[0003] However, in the actual application of the medical equipment for assisted breathing such as an anesthesia machine or a breathing machine, in order to ensure that the equipment can work normally, a system self-check is usually required before ventilation after each power-on of the equipment, for testing the leakage and the system compliance. At this time, the traditional detection method is difficult to meet the actual application requirements, and therefore most of the equipment adopts a method of maintaining the gas flow rate by the pressure provided by the equipment itself, and maintaining the airway pressure to achieve a specific target. However, due to the reasons of the equipment itself, the flow rate sensor provided by the medical equipment such as an anesthesia machine or a breathing machine is difficult to measure such a small gas flow rate when the gas leakage is less than 1000 ml / min, which will cause a large deviation of the final leakage and compliance.

[0004] However, the existing compliance measurement methods cannot accurately measure the compliance of the system, and the measurement method of the static compliance is very complex. Some calculation methods need to know the accurate pipeline volume in advance to calculate the leakage and compliance.

[0005] Based on the above description, there is an urgent need for a simple and easy-to-operate system leakage and static compliance detection method to accurately measure the system leakage and static compliance during system self-check. SUMMARY

[0006] The main purpose of the present application is to provide a compliance and leakage determination method and device, equipment and storage medium, which can solve the problem of lack of simple and easy-to-operate system leakage and static compliance detection method in the prior art.

[0007] To achieve the above object, the present application provides a method for determining compliance and leakage, comprising:

[0008] The method is applied to a breathing assistance system, which comprises at least a gas flow pipeline provided with an inhalation valve, and comprises:

[0009] acquiring real-time flow rate flowing through the inhalation valve and simulated breathing data, wherein the simulated breathing data comprises inhalation data and exhalation data, the inhalation data comprises inhalation start time and inhalation end time, and the exhalation data comprises exhalation start time and exhalation end time;

[0010] determining pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inhalation start time, the inhalation end time, the exhalation start time and the exhalation end time;

[0011] determining system leakage of the breathing assistance system by using the exhalation start time and the inhalation start time.

[0012] In a feasible implementation manner, the simulated breathing data comprises at least two groups, and the at least two groups of simulated breathing data are determined by adjacent simulated breathings, and the determination of the pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inhalation start time, the inhalation end time, the exhalation start time and the exhalation end time comprises:

[0013] inputting the first group of inhalation start time, the first group of inhalation end time, the first group of exhalation start time, the first group of exhalation end time and the second group of exhalation start time, the real-time flow rate and the real-time pressure of the gas pipeline into a preset pipeline compliance calculation model to determine the pipeline compliance of the gas flow pipeline.

[0014] In a feasible implementation manner, the determination of the system leakage of the breathing assistance system by using the exhalation start time and the inhalation start time comprises:

[0015] inputting the first group of exhalation start time, the first group of exhalation end time and the second group of exhalation start time and the real-time pressure of the pipeline into a preset system leakage calculation model to determine the system leakage of the breathing assistance system.

[0016] In a feasible implementation manner, the pipeline compliance calculation model comprises the following mathematical expression:

[0017]

[0018] In the formula, C tube is the pipeline compliance, T0 is the first group of inspiration start time, T 1 is the first group of inspiration end time, T 2 is the first group of expiration start time, T 3 is the first group of expiration end time, and T 5 is the second group of expiration start time, flow insp is the real-time flow rate, P is the real-time pressure of the gas pipeline, represents the pressure change, P1 is the target pressure, and P0 is the initial pressure.

[0019] In a feasible implementation manner, the system leakage amount calculation model comprises the following mathematical expression:

[0020] ;

[0021] In the formula, F_leak tube is the system leakage amount, T 2 is the first group of expiration start time, T 3 is the first group of expiration end time, T 5 is the second group of expiration start time, P is the real-time pressure of the gas pipeline.

[0022] In a feasible implementation manner, the method for obtaining the simulated breathing data comprises the following steps:

[0023] controlling the expiration end of the gas flow pipeline to be in a closed state and the inspiration end to be in an open state, and recording the initial pressure and the first group of inspiration start time;

[0024] controlling the inspiration flow rate to be constant until the pipeline pressure of the gas flow pipeline reaches the target pressure, recording the target pressure and the first group of inspiration end time;

[0025] when the pipeline pressure of the gas flow pipeline remains unchanged for a period of time, recording the first group of expiration start time, and controlling the inspiration valve to be in a closed state until the pipeline pressure of the gas flow pipeline reaches the minimum pressure threshold, recording the first group of expiration end time;

[0026] returning to the step of controlling the expiration end of the gas flow pipeline to be in a closed state and the inspiration end to be in an open state, and recording the initial pressure and the first group of inspiration start time, obtaining the second group of inspiration start time, the second group of inspiration end time, the second group of expiration start time, and then controlling the exhaust valve to be in an open state to exhaust, so as to end the simulated breathing, thereby obtaining the simulated breathing data.

[0027] In a feasible implementation manner, the method further comprises:

[0028] Compensate the gas flow of the breathing assistance system based on the pipeline compliance and the system leakage amount, so as to reduce the error of the gas flow of the breathing assistance system.

[0029] To achieve the above object, the second aspect of the present application provides a compliance and leakage amount determination device, which comprises:

[0030] The device is applied to a breathing assistance system, and the breathing assistance system at least comprises a gas flow pipeline, and the gas flow pipeline is provided with an inhalation valve.

[0031] The data acquisition module is configured to acquire real-time flow rate flowing through the inhalation valve and simulated breathing data, and the simulated breathing data comprises inhalation data and exhalation data.

[0032] The compliance determination module is configured to determine the pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inhalation start time, the inhalation end time, the exhalation start time and the exhalation end time.

[0033] The leakage amount determination module is configured to determine the system leakage amount of the breathing assistance system by using the exhalation start time and the inhalation start time.

[0034] To achieve the above object, the third aspect of the present application provides a computer readable storage medium, which stores a computer program, and the computer program is executed by a processor to make the processor execute the steps of the first aspect and any feasible implementation manner.

[0035] To achieve the above object, the fourth aspect of the present application provides a computer device, which comprises a memory and a processor, and the memory stores a computer program, and the computer program is executed by the processor to make the processor execute the steps of the first aspect and any feasible implementation manner.

[0036] By adopting the embodiments of the present application, the following beneficial effects are achieved:

[0037] The application provides a compliance and leakage amount determination method, which is applied to a breathing assistance system, and the breathing assistance system at least comprises a gas flow pipeline, and the gas flow pipeline is provided with an inhalation valve. The method comprises the following steps: acquiring real-time flow rate flowing through the inhalation valve and simulation breathing data, wherein the simulation breathing data comprises inhalation data and exhalation data; the inhalation data comprises inhalation start time and inhalation end time, and the exhalation data comprises exhalation start time and exhalation end time; determining pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inhalation start time, the inhalation end time, the exhalation start time and the exhalation end time; and determining system leakage amount of the breathing assistance system by using the exhalation start time and the inhalation start time. In this way, the breathing assistance system can realize self-checking of the leakage amount and the pipeline compliance without using a high-precision flow sensor and a flow control valve, and the leakage amount and the pipeline compliance can be obtained by using the simulation breathing data, thereby greatly reducing equipment cost. BRIEF DESCRIPTION OF DRAWINGS

[0038] In order to more clearly illustrate the technical solutions of the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or the prior art description. Obviously, the drawings in the following description are only some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings.

[0039] Among them:

[0040] Figure 1 It is a flow chart of the compliance and leakage amount determination method in the embodiment of the present application.

[0041] Figure 2 It is another flow chart of the compliance and leakage amount determination method in the embodiment of the present application.

[0042] Fig. 3(a) is a pressure and time waveform of the pipeline compliance and leakage amount determination method in the embodiment, and Fig. 3(b) is a flow rate and time waveform of the pipeline compliance and leakage amount determination method in the embodiment.

[0043] Figure 4 It is a structural block diagram of the compliance and leakage amount determination device in the embodiment of the present application.

[0044] Figure 5 It is a structural block diagram of the computer device in the embodiment of the present application. DETAILED DESCRIPTION

[0045] With reference to the drawings of the embodiments of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described. Obviously, the described embodiments are only a part of the embodiments of the present application, but not all the embodiments of the present application. Based on the embodiments of the present application, all the other embodiments obtained by a person of ordinary skill in the art without creative work fall within the protection scope of the present application.

[0046] Please refer to Figure 1 , Figure 1 The flow chart of a compliance and leak determination method in an embodiment of the present application is shown in Figure 1 The method comprises the following steps:

[0047] 101, obtaining a real-time flow rate flowing through the inhalation valve and simulated breathing data, the simulated breathing data comprising inhalation data and exhalation data; the inhalation data comprising an inhalation start time and an inhalation end time, and the exhalation data comprising an exhalation start time and an exhalation end time;

[0048] It should be noted that the method shown in Figure 1 is applied to a breathing assistance system, which comprises but is not limited to a control system of a medical device for assisting breathing, such as an anesthetizer or a ventilator, etc. The breathing assistance system at least comprises a gas flow pipeline, a gas source, etc. The gas flow pipeline is provided with an inhalation valve, wherein the gas flow pipeline serves as a channel for transmitting gas, so that the gas can be transmitted in the pipeline, and the gas can be emitted by the gas source. The determination of the pipeline compliance and the system leak can be achieved by monitoring the parameter changes during simulated breathing, and the system leak and the pipeline compliance are calculated accordingly. Therefore, first, the real-time flow rate flowing through the inhalation valve and the simulated breathing data are obtained, the simulated breathing data comprising inhalation data and exhalation data; the inhalation data comprising an inhalation start time and an inhalation end time, and the exhalation data comprising an exhalation start time and an exhalation end time. It should be noted that the simulated breathing data is obtained by adjusting the working state of each element in the breathing assistance system to simulate inflation or deflation, rather than real breathing behavior, such as controlling the opening and closing of the inhalation valve or the exhaust valve, etc. A plurality of breathing cycles can be simulated to obtain a plurality of sets of simulated breathing data, thereby improving the accuracy of the data and the accuracy of the subsequent calculation of the pipeline compliance and the system leak. One breathing cycle also includes a set of inhalation data and exhalation data.

[0049] 102, determining the pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inhalation start time, the inhalation end time, the exhalation start time and the exhalation end time;

[0050] 103. Determine the system leakage of the respiratory assistance system by using the expiration start time and the inspiration start time.

[0051] Further, after obtaining the expiration data and the inspiration data, the pipeline compliance of the gas circulation pipeline and the system leakage of the respiratory assistance system can be obtained by using the real-time flow rate, the inspiration data, the expiration data and the inspiration valve, specifically, the pipeline compliance of the gas circulation pipeline is determined by using the real-time flow rate, the inspiration start time, the inspiration end time, the expiration start time and the expiration end time; the system leakage of the respiratory assistance system is determined by using the expiration start time and the inspiration start time, wherein the pipeline compliance can be referred to as compliance, and the system leakage can be referred to as leakage. It can be seen that, by the above method, the compliance and the leakage can be determined without using high-precision flow sensors and flow control valves, and without knowing the accurate pipeline volume, and the determination method is simple and easy to operate.

[0052] The present application provides a compliance and leakage determination method, which is applied to a respiratory assistance system, and the respiratory assistance system at least includes a gas circulation pipeline, and the gas circulation pipeline is provided with an inspiration valve, and the method includes: obtaining a real-time flow rate flowing through the inspiration valve and simulation breathing data, the simulation breathing data including inspiration data and expiration data; the inspiration data including an inspiration start time and an inspiration end time, and the expiration data including an expiration start time and an expiration end time; determining the pipeline compliance of the gas circulation pipeline by using the real-time flow rate, the inspiration start time, the inspiration end time, the expiration start time and the expiration end time; and determining the system leakage of the respiratory assistance system by using the expiration start time and the inspiration start time. By the above method, the respiratory assistance system can realize self-checking of the leakage and the pipeline compliance without using high-precision flow sensors and flow control valves, and the leakage and the pipeline compliance can be obtained by using the simulation breathing data, thereby greatly reducing the equipment cost.

[0053] Please refer to Figure 2 , Figure 2 Another flow chart of the compliance and leakage determination method of the pipeline is shown in the embodiment of the present application, and the method is applied to a respiratory assistance system, and the respiratory assistance system at least includes a gas circulation pipeline, and the gas circulation pipeline is provided with an inspiration valve, and the method includes: Figure 2 Figure 2

[0054] 201. Obtain a real-time flow rate flowing through the inspiration valve and simulation breathing data, and the simulation breathing data includes inspiration data and expiration data; the inspiration data includes an inspiration start time and an inspiration end time, and the expiration data includes an expiration start time and an expiration end time;

[0055] ​​It should be noted that step 201 and Figure 1 The content of step 101 shown is similar, and to avoid repetition, it will not be repeated here. Please refer to the previous section for details. Figure 1 The content of step 101 shown.

[0056] In one feasible implementation, the acquisition of the simulated breathing data requires measurement. The simulated breathing data includes at least two sets, and these at least two sets are determined by adjacent simulated breaths, i.e., two consecutive simulated breaths are performed to obtain the at least two sets of simulated breathing data. Further, taking two consecutive simulated breaths as an example, the specific measurement method for the two sets of simulated breathing data is explained below, please refer to steps A1-A4:

[0057] A1. Control the expiratory end of the gas flow pipeline to be closed and the inhalation end to be open, and record the initial pressure and the start time of the first inhalation.

[0058] First, after connecting the tubing, the exhalation end needs to be blocked, keeping the gas flow closed at the exhalation end and open at the inhalation end. Record the initial pressure at this point. P 1 and the start time of the first inhalation T 0. This initiates the first inhalation in the first simulated breathing exercise. The start time of the first inhalation is the moment the inhalation end is open after the tubing is connected.

[0059] A2. Control the inhalation flow rate with a constant flow rate until the pipeline pressure of the gas flow pipeline reaches the target pressure, and record the target pressure and the end time of the first inhalation.

[0060] Furthermore, the intake flow rate is controlled at a constant flow rate until the pipeline pressure in the gas flow pipeline reaches the target pressure, thereby ensuring a constant intake flow rate and achieving the target pressure. At this point, the target pressure should be recorded. P 1 and the end time of the first inhalation T 1. The end time of the first intake is the moment when the pipeline pressure reaches the target pressure.

[0061] A3. When the pressure in the gas flow tubing remains constant for a period of time, record the start time of the first set of exhalations; and control the inhalation valve to be in the closed state until the pressure in the gas flow tubing reaches the minimum pressure threshold, and record the end time of the first set of exhalations.

[0062] Furthermore, after a certain delay, wait for the overall condition of the pipeline to stabilize. When the pressure in the gas flow pipeline remains constant for a period of time (i.e., the overall condition of the pipeline is stable), record the start time of the first set of exhalations.T 2, and after the overall state of the pipeline is stable, the first expiration operation in the first simulated respiration operation is started. By closing the inspiration valve, the control inspiration valve is kept in a closed state, the expiration end is kept closed until the pipeline pressure of the gas flow pipeline reaches the minimum pressure threshold, at which time the first expiration end time is recorded T 3, wherein the first expiration start time is the time when the overall state of the pipeline is stable, and the first expiration end time is the time when the pipeline pressure of the gas flow pipeline reaches the minimum pressure threshold. The minimum pressure threshold can be a pressure reaching a minimum threshold or a pressure threshold obtained after a waiting time reaches a preset length of time.

[0063] A4, return to execute the step of controlling the expiration end of the gas flow pipeline to be in a closed state and the inspiration end to be in an open state, and recording the starting pressure and the first inspiration start time, obtaining the second inspiration start time, the second inspiration end time, the second expiration start time, and then controlling the exhaust valve to be in an open state for exhaust to end the simulated respiration to obtain simulated respiration data.

[0064] Further, after obtaining the first group of simulated respiration data, the measurement and acquisition of the second group of simulated respiration data can be continued, and the process is similar to that of the first group of simulated respiration. For reference, the second inspiration start time is the first expiration end time, and the inspiration process of the second group of simulated respiration is started: first, as in step A2 above, the inspiration flow is constant, and the pipeline pressure is restored to the target pressure, which is the same as the target pressure described above, and the second inspiration end time is recorded at this time T 4; further, as in step A3 above, delay for a period of time to wait for the pipeline pressure to stabilize, and record the second expiration start time at this time T 5; finally, open the inspiration valve, close the inspiration valve for exhaust, and the measurement is ended. Further, reference can be made to FIG. 3, including FIG. 3(a) and FIG. 3(b), FIG. 3(a) is a pressure-time waveform of a pipeline compliance and leakage amount determination method in this embodiment, and FIG. 3(b) is a flow rate-time waveform of a pipeline compliance and leakage amount determination method in this embodiment. In the figure, V 1_all and V 2_all for indicating the volume of gas, wherein, V 1_all is the volume entering the pipeline within a time, V 2_all is T 3- T 4 the volume entering the pipeline within a time.

[0065] Flow rate and pressure, among other parameters, can be collected using appropriate sensors; no specific type is specified here. The measurement method is described in detail below: Connect the tubing and block the expiratory end; record the initial pressure. ( Then, a constant intake flow rate (greater than the maximum leakage flow rate to be monitored) is applied. Once the target pressure is reached, record the pressure at that point. ( ), wait for a while ( (The inhalation velocity during this time is...) (Pipeline leakage under pressure) Close the intake valve to seal the entire pipeline. ), after a period of time or when the pressure drops to the minimum pressure threshold ( The intake valve opens to provide a constant intake flow rate or directly... Pressure control for target values ​​( ), waiting for the pressure to stabilize ( The entire measurement is now complete, and the waveforms shown in Figure 3(a) and Figure 3(b) above are obtained. Assuming there is some leakage in the tubing, this method can accurately calculate the leakage amount and tubing compliance when the ventilator performs a system self-test. Please refer to the following content for details.

[0066] 202. Input the first group of inhalation start time, the first group of inhalation end time, the first group of exhalation start time, the first group of exhalation end time, the second group of exhalation start time, the real-time flow rate, and the real-time pressure of the gas pipeline into a preset pipeline compliance calculation model to determine the pipeline compliance of the gas flow pipeline.

[0067] It should be noted that after obtaining the above two sets of simulated breathing data, the pipeline compliance of the gas flow pipeline can be obtained using a preset pipeline compliance calculation model. Specifically, the first set of inhalation start time, the first set of inhalation end time, the first set of exhalation start time, the first set of exhalation end time, the second set of exhalation start time, the real-time flow rate, and the real-time pressure of the gas pipeline are input into the preset pipeline compliance calculation model to determine the pipeline compliance of the gas flow pipeline.

[0068] For example, the pipeline compliance calculation model includes the following mathematical expression:

[0069]

[0070] In the formula, C tube For pipeline compliance, T 0 represents the start time of the first inhalation. T 1 represents the end time of the first inhalation. T2 is a first group of expiration start time, T 3 is a first group of expiration end time, and T 5 is a second group of expiration start time, flow insp is a real-time flow rate, P is a real-time pressure of the gas pipeline, represents a pressure change, P1 is a target pressure, and P0 is a starting pressure.

[0071] 203, input the first group of expiration start time, the first group of expiration end time, the second group of expiration start time, and the real-time pressure of the pipeline into a preset system leakage calculation model to determine the system leakage of the respiratory assistance system;

[0072] It should be noted that after obtaining the above two groups of simulated breathing data, the system leakage of the respiratory assistance system can be obtained by using the preset system leakage calculation model. Specifically, the first group of expiration start time, the first group of expiration end time, the second group of expiration start time, and the real-time pressure of the pipeline are input into the preset system leakage calculation model to determine the system leakage of the respiratory assistance system.

[0073] For example, the above system leakage calculation model includes the following mathematical expression:

[0074]

[0075] In the formula, F_leak tube is the system leakage, T 2 is a first group of expiration start time, T 3 is a first group of expiration end time, T 5 is a second group of expiration start time, P is a real-time pressure of the gas pipeline.

[0076] To better understand this embodiment, the derivation process of the mathematical expression of the above model is given below. It should be noted that the calculation process of the pipeline compliance and the leakage assumes that there is a certain leakage in the pipeline, and the calculation method and the derivation process are as follows:

[0077] Among them, the pipeline compliance is mainly obtained by the pressure and volume change in the time period, and its calculation formula is:

[0078] (1-1)

[0079] In the formula, C is the pipeline compliance, is the volume change in the time period is​ pressure change over a time period, T 0 is the start time of the first group of inhalations, T 1 is the end time of the first group of inhalations.

[0080] The compliance of the line can be obtained in combination with Figure 3 as:

[0081] (1-2)

[0082] where, C tube is the compliance of the line, V 1_all is the volume of gas flowing into the line over time, P 0 is the start pressure, P 1 is the target pressure, T 0 is the start time of the first group of inhalations, T 1 is the end time of the first group of inhalations.

[0083] When there is a leak in the line, the volume entering the line over time is no longer equal to V 1_all but needs to subtract the volume of the leak V 1_leak At this time, the compliance of the line is:

[0084] (1-3)

[0085] where, C tube is the compliance of the line, V 1_all is the volume of gas flowing into the line over time, P 0 is the start pressure, P 1 is the target pressure, V 1_leak is the volume of the leak in the line over time, flow insp is the real-time flow rate through the inhalation valve, flow leak is the real-time leak flow rate of the line, T 0 is the start time of the first group of inhalations, T 1 is the end time of the first group of inhalations.

[0086] As can be seen from equation 1-3, the key to obtaining the compliance of the line C tube is to calculate the real-time leak flow rate of the line flow leakAnd after the real-time leakage flow rate is obtained, the leakage amount of the pipeline can also be calculated, flow leak which needs to be calculated afterwards.

[0087] Further, it is assumed that the leakage factor of the pipeline is k According to Bernoulli's principle:

[0088] (1-4)

[0089] In the formula, k is the leakage factor of the pipeline, flow leak is the real-time leakage flow rate of the pipeline, P is the real-time pressure of the gas pipeline.

[0090] Wherein The pressure drop value of is consistent with the pressure rise value at the moment, so the pipeline compliance calculated in the two stages is also consistent, The change in the volume of the pipeline in the time period is caused by the implementation of the leakage of the pipeline, and The change in the volume of the pipeline in the time period is caused by the suction valve controlled suction flow rate and the real-time leakage, so from formula (1-1) we can get:

[0091] (1-5)

[0092] Because the pressure changes in the two time periods are the same, it can be further simplified as:

[0093] (1-6)

[0094] (1-7)

[0095] Combined with formula 1-4, we can get:

[0096] (1-8)

[0097] (1-9)

[0098] Substituting formula 1-3, we can get the compliance of the pipeline:

[0099] (1-10)

[0100] Substituting formula 1-9 into formula 1-4, we can get the leakage amount of the pipeline (usually 50 cmH2O pressure) as:

[0101] (1-11)

[0102] Further, the above-mentioned formula (1-10) and formula (1-11) are obtained to calculate the pipeline compliance and the system leakage.

[0103] Further, the present application aims to provide a method for self-checking compliance and leakage of a computing system of an anesthesia machine or a breathing machine. The method can accurately measure the static compliance and leakage of the anesthesia machine system itself, and provides accurate basis for compensation of tidal volume monitoring and control algorithm in mode control. Further, after obtaining the pipeline compliance and the system leakage, the gas flow of the breathing assistance system can be compensated based on the pipeline compliance and the system leakage to reduce the error of the gas flow of the breathing assistance system.

[0104] The present application provides a method for determining compliance and leakage, which is applied to a breathing assistance system. The breathing assistance system at least includes a gas flow pipeline, and the gas flow pipeline is provided with an inhalation valve. The method comprises the following steps: acquiring real-time flow rate flowing through the inhalation valve and simulated breathing data, wherein the simulated breathing data comprises inhalation data and exhalation data; the inhalation data comprises inhalation start time and inhalation end time, and the exhalation data comprises exhalation start time and exhalation end time; inputting the first group of inhalation start time, the first group of inhalation end time, the first group of exhalation start time, the first group of exhalation end time, the second group of exhalation start time, the real-time flow rate, and the real-time pressure of the gas pipeline into a preset pipeline compliance calculation model to determine the pipeline compliance of the gas flow pipeline; and inputting the first group of exhalation start time, the first group of exhalation end time, the second group of exhalation start time, and the real-time pressure of the pipeline into a preset system leakage calculation model to determine the system leakage of the breathing assistance system. In this way, the breathing assistance system can realize self-checking of the leakage and the pipeline compliance without using high-precision flow sensors and flow control valves, and the leakage and the pipeline compliance can be obtained through the simulated breathing data, thereby greatly reducing the equipment cost.

[0105] Please refer to Figure 4 , Figure 4 The structure block diagram of a device for determining pipeline compliance and leakage in an embodiment of the present application is shown in Figure 4 The device is applied to a breathing assistance system, and the breathing assistance system at least includes a gas flow pipeline, and the gas flow pipeline is provided with an inhalation valve. The device is shown in Figure 4 The device comprises:

[0106] The data acquisition module 401 is configured to acquire real-time flow rate flowing through the inhalation valve and simulated breathing data, wherein the simulated breathing data comprises inhalation data and exhalation data; the inhalation data comprises inhalation start time and inhalation end time, and the exhalation data comprises exhalation start time and exhalation end time.

[0107] The pipeline compliance determination module 402 is configured to determine the pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inspiration start time, the inspiration end time, the expiration start time and the expiration end time.

[0108] The leakage amount determination module 403 is configured to determine the system leakage amount of the respiratory assistance system by using the expiration start time and the inspiration start time.

[0109] It should be noted that, Figure 4 the functions of the modules in the device are similar to the contents of the steps in the method. Figure 1 the functions of the modules in the device are similar to the contents of the steps in the method. Figure 1 the functions of the modules in the device are similar to the contents of the steps in the method.

[0110] The present application provides a compliance and leakage amount determination device. The device is applied to a respiratory assistance system, and the respiratory assistance system at least comprises a gas flow pipeline provided with an inspiration valve. The device comprises: a data acquisition module configured to acquire a real-time flow rate flowing through the inspiration valve and simulation breathing data, the simulation breathing data comprising inspiration data and expiration data; the inspiration data comprising an inspiration start time and an inspiration end time, and the expiration data comprising an expiration start time and an expiration end time; a compliance determination module configured to determine the pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inspiration start time, the inspiration end time, the expiration start time and the expiration end time; and a leakage amount determination module configured to determine the system leakage amount of the respiratory assistance system by using the expiration start time and the inspiration start time. In this way, the respiratory assistance system can realize self-checking of the leakage amount and the pipeline compliance without using a high-precision flow sensor and a flow control valve, and the leakage amount and the pipeline compliance can be obtained by using the simulation breathing data, thereby greatly reducing the equipment cost.

[0111] Figure 5 An internal structure diagram of a computer device in an embodiment is shown. The computer device can be a terminal or a server. As shown in the figure, Figure 5 The computer device comprises a processor, a memory and a network interface connected through a system bus. The memory comprises a non-volatile storage medium and an internal memory. The non-volatile storage medium of the computer device stores an operating system and can also store a computer program, which, when executed by the processor, can enable the processor to implement the above method. The internal memory can also store a computer program, which, when executed by the processor, can enable the processor to execute the above method. Those skilled in the art can understand that, Figure 5The structure shown in the figure is only a block diagram of part of the structure related to the scheme of the present application, and does not constitute a limitation on the computer device to which the scheme of the present application is applied. The specific computer device can include more or fewer components than those shown in the figure, or combine certain components, or have a different arrangement of components.

[0112] In one embodiment, a computer device is provided, comprising a memory and a processor, the memory storing a computer program, the computer program being executed by the processor to cause the processor to perform the steps of the method described above. Figure 1 or Figure 2 In one embodiment, a computer readable storage medium is provided, storing a computer program, the computer program being executed by a processor to cause the processor to perform the steps of the method described above.

[0113] In one embodiment, a computer readable storage medium is provided, storing a computer program, the computer program being executed by a processor to cause the processor to perform the steps of the method described above. Figure 1 or Figure 2 In one embodiment, a computer readable storage medium is provided, storing a computer program, the computer program being executed by a processor to cause the processor to perform the steps of the method described above.

[0114] A person of ordinary skill in the art can understand that all or part of the processes in the above-mentioned embodiments can be completed by a computer program instructing related hardware. The program can be stored in a non-volatile computer readable storage medium, and when executed, can include the processes of the above-mentioned embodiments. Any reference to memory, storage, database or other medium used in the embodiments provided by the present application can include non-volatile and / or volatile memory. Non-volatile memory can include read-only memory (ROM), programmable ROM (PROM), electrically programmable ROM (EPROM), electrically erasable programmable ROM (EEPROM) or flash memory. Volatile memory can include random access memory (RAM) or external cache memory. As an illustration but not limitation, RAM is available in various forms, such as static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double data rate SDRAM (DDR SDRAM), enhanced SDRAM (ESDRAM), synchronous link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM), etc.

[0115] The technical features of the above embodiments can be combined in any way. In order to make the description concise, not all possible combinations of the technical features in the above embodiments are described, but as long as the combinations of the technical features do not exist, they should be considered as within the scope of the present application.

[0116] The above-described embodiments are merely illustrative of several embodiments of the present application, which are described in more detail and in a specific and detailed manner, but should not be construed as limiting the scope of the patent of the present application. It should be noted that, for those of ordinary skill in the art, several modifications and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application should be subject to the appended claims.

Claims

1. A method of determining compliance and leakage, characterized by, The method is applied to a respiratory assistance system, the respiratory assistance system at least comprising a gas flow circuit, the gas flow circuit being provided with an inhalation valve, the method comprising: acquiring real-time flow rate flowing through the inhalation valve and simulated breathing data, the simulated breathing data comprising inhalation data and exhalation data; the inhalation data comprising inhalation start time and inhalation end time, the exhalation data comprising exhalation start time and exhalation end time; determining circuit compliance of the gas flow circuit by using the real-time flow rate, the inhalation start time, the inhalation end time, the exhalation start time and the exhalation end time; determining system leakage of the respiratory assistance system by using the exhalation start time and the inhalation start time; wherein the simulated breathing data comprises at least two groups, and at least two groups of the simulated breathing data are determined by adjacent simulated breathing, and the determining circuit compliance of the gas flow circuit by using the real-time flow rate, the inhalation start time, the inhalation end time, the exhalation start time and the exhalation end time comprises: inputting the first group of inhalation start time, the first group of inhalation end time, the first group of exhalation start time, the first group of exhalation end time and the second group of exhalation start time, the real-time flow rate and the real-time pressure of the gas circuit into a preset circuit compliance calculation model to determine the circuit compliance of the gas flow circuit; wherein the acquiring simulated breathing data comprises: controlling the exhalation end of the gas flow circuit to be in a closed state and the inhalation end to be in an open state; controlling the inhalation flow rate at a constant flow rate until the circuit pressure of the gas flow circuit reaches a target pressure; when the circuit pressure of the gas flow circuit remains unchanged for a period of time, recording the first group of exhalation start time, and controlling the inhalation valve to be in a closed state; wherein the circuit compliance calculation model comprises the following mathematical expression: wherein C tube is the line compliance, T0 is the first set of inhalation start times, T1 is the first set of inhalation end times, T2 is the first set of exhalation start times, T3 is the first set of exhalation end times, and T5 is the second set of exhalation start times, flow insp is the real-time flow rate, P is the real-time pressure of the gas line, P1-P0 represents the pressure change, P1 is the target pressure, and P0 is the starting pressure.

2. The method of claim 1, wherein, the determining system leakage of the respiratory assistance system by using the exhalation start time and the inhalation start time comprises: inputting the first group of exhalation start time, the first group of exhalation end time and the second group of exhalation start time and the real-time pressure of the circuit into a preset system leakage calculation model to determine the system leakage of the respiratory assistance system.

3. The method of claim 2, wherein, The system leakage calculation model comprises the following mathematical expression: where F_leak tube is the system leak, T2 is the start time of the first group expiration, T3 is the end time of the first group expiration, T5 is the start time of the second group expiration, and P is the real-time pressure of the gas line.

4. The method of claim 1, wherein, The acquiring simulated breathing data comprises: controlling the exhalation end of the gas flow circuit to be in a closed state and the inhalation end to be in an open state, and recording the initial pressure and the first group of inhalation start time; controlling the inhalation flow rate at a constant flow rate until the circuit pressure of the gas flow circuit reaches a target pressure, recording the target pressure and the first group of inhalation end time; when the circuit pressure of the gas flow circuit remains unchanged for a period of time, recording the first group of exhalation start time; and controlling the inhalation valve to be in a closed state until the circuit pressure of the gas flow circuit reaches a minimum pressure threshold, recording the first group of exhalation end time; The step of controlling the exhaust valve to be in an open state to exhaust gas to end the simulated breathing to obtain the simulated breathing data is performed after the step of controlling the expiratory end of the gas flow pipeline to be in a closed state and the inspiratory end to be in an open state, recording the initial pressure and the first set of inspiratory start time, obtaining the second set of inspiratory start time, the second set of inspiratory end time, the second set of expiratory start time.

5. The method of claim 1, wherein, The method further comprises: Compensating the gas flow of the breathing assistance system based on the pipeline compliance and the system leakage amount to reduce the error of the gas flow of the breathing assistance system.

6. A compliance and leakage amount determination device characterized by comprising: The device is applied to a breathing assistance system, and the breathing assistance system at least comprises a gas flow pipeline provided with an inspiratory valve, and the device comprises: a data acquisition module configured to acquire real-time flow rate flowing through the inspiratory valve and simulated breathing data, the simulated breathing data comprising inspiratory data and expiratory data; the inspiratory data comprising inspiratory start time and inspiratory end time, and the expiratory data comprising expiratory start time and expiratory end time; a compliance determination module configured to determine pipeline compliance of the gas flow pipeline by using the real-time flow rate, the inspiratory start time, the inspiratory end time, the expiratory start time and the expiratory end time; a leakage amount determination module configured to determine system leakage amount of the breathing assistance system by using the expiratory start time and the inspiratory start time; wherein the simulated breathing data comprises at least two sets, and at least two sets of the simulated breathing data are determined by adjacent simulated breathings, and the compliance determination module is specifically configured to input the first set of inspiratory start time, the first set of inspiratory end time, the first set of expiratory start time, the first set of expiratory end time, the second set of expiratory start time, the real-time flow rate and the real-time pressure of the gas pipeline into a preset pipeline compliance calculation model to determine the pipeline compliance of the gas flow pipeline; wherein the data acquisition module is specifically configured to control the expiratory end of the gas flow pipeline to be in a closed state and the inspiratory end to be in an open state; control the inspiratory flow rate at a constant flow rate until the pipeline pressure of the gas flow pipeline reaches a target pressure; when the pipeline pressure of the gas flow pipeline remains unchanged for a period of time, record the first set of expiratory start time, and control the inspiratory valve to be in a closed state; wherein the pipeline compliance calculation model comprises the following mathematical expression: where C tube is the line compliance, T0 is the first group inhalation start time, T1 is the first group inhalation end time, T2 is the first group exhalation start time, T3 is the first group exhalation end time, and T5 is the second group exhalation start time, flow insp is the real-time flow rate, P is the real-time pressure of the gas line, P1-P0 represents the pressure change, P1 is the target pressure, and P0 is the starting pressure.

7. A computer readable storage medium storing a computer program, wherein the computer program comprises program instructions configured to cause a processor to perform the method according to any one of claims 1 to 6. The computer program is executed by the processor to make the processor perform the steps of the method of any one of claims 1 to 5. 8.A computer device, comprising a memory and a processor, and characterized in that, The memory stores a computer program, and the computer program is executed by the processor to make the processor perform the steps of the method of any one of claims 1 to 5.

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