A lactation diet for increasing the iron content of sow milk

A fermented feed made from fermented wheat bran and soybean meal, combined with a compound iron source and eugenol, was used to prepare a lactation feed. This solved the problem of low iron content in sow milk, significantly increasing the iron content in milk and promoting healthy growth in piglets.

CN117481267BActive Publication Date: 2025-12-05SHANDONG AGRICULTURAL UNIVERSITY +1
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Patent Information

Application Number
CN202311672291.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-12-07
Publication Date
2025-12-05
Estimated Expiration
2043-12-07

AI Technical Summary

Technical Problem

The iron content in sow's milk is low, which cannot meet the iron requirements of piglets during their rapid growth, thus affecting the sustainable and healthy development of the pig farming industry.

Method used

Fermented feed was prepared by fermenting wheat bran and soybean meal with specific strains of bacteria, and then compounded with a compound iron source and eugenol to prepare lactation feed, which was added to the daily diet of sows to increase the iron content in milk.

Benefits of technology

It significantly increases the iron content in sow's milk, ensuring the iron requirements for piglet growth, improving piglet survival rate and birth and weaning weight, and ensuring piglet health.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application provides a lactation material for increasing iron content in sow milk, and relates to the field of agricultural technology. The raw material of the lactation material comprises the following components in parts by mass: 2-3 parts of an iron source, 5-8 parts of fermentation material, and 0.8-1.0 parts of eugenol; the fermentation material is prepared by fermenting wheat bran and soybean meal with Bacillus polymyxa; and the iron source is a composite iron source composed of glycine ferrous, methionine ferrous and fumarate ferrous. The lactation material can significantly improve the iron content in the milk of sows in the lactation period, ensure the iron demand of piglets, and improve the survival rate of piglets, birth weight and weaning weight, and ensure the health of piglets, under the condition of a small amount of addition in the daily ration.
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Description

TECHNICAL FIELD

[0001] The present application relates to the field of agricultural technology, in particular to a lactation material for increasing the iron content in sow milk. BACKGROUND

[0002] Pig industry is an important pillar of agricultural economic development, in the modern intensive farming mode, sows are the key to ensure the sustainable and healthy development of pig population. Sow milk contains a variety of nutrients, including vitamins, proteins, minerals and other nutrients, which are important sources of nutrients for piglets.

[0003] Iron is one of the essential nutrients for animal body, which is the component of hemoglobin and myoglobin, and directly affects the hematopoietic function of animal body. Although the newborn piglets have a certain amount of iron storage, the content is low, and milk is the main source of nutrients for piglets before 20 days old, and the iron required for the growth of piglets is also mainly obtained from milk. However, the content of iron in the milk of production sows is very low, and in the traditional breeding mode, the content of iron in the milk is only about 1.3mg / L, while piglets grow rapidly, and the total blood volume increases rapidly with the increase of body weight, therefore, it is imperative to increase the content of iron in the milk of production sows, which is of great significance to ensure the sustainable and healthy development of pig industry. SUMMARY

[0004] The purpose of the present application is to provide a lactation material for increasing the iron content in sow milk, so as to solve the problems existing in the prior art, and to increase the content of iron in sow milk and promote the sustainable and healthy development of pig industry.

[0005] To achieve the above-mentioned purpose, the present application provides the following scheme:

[0006] The present application provides a lactation material for increasing the iron content in sow milk, and the raw materials include the following components by mass:

[0007] 2-3 parts of iron source, 5-8 parts of fermented material, 0.8-1.0 parts of eugenol;

[0008] The fermented material is prepared by fermenting wheat bran and soybean meal with Paenibacillus polymyxa.

[0009] The iron source is a composite iron source composed of glycine ferrous, methionine ferrous and fumarate ferrous.

[0010] As a further preferred embodiment of the present application, the mass ratio of glycine ferrous, methionine ferrous and fumarate ferrous is 1:(1-2):2; more preferably 1:1.5:2.

[0011] As a further preferred embodiment of the present application, the fermentation temperature is 35-37℃; more preferably 37℃.

[0012] As a further preferred embodiment of the present application, the fermentation time is 48-60h; more preferably, the fermentation time is 48h.

[0013] As a further preferred embodiment of the present application, the Paenibacillus polymyxa is Paenibacillus polymyxa DYr4.4.

[0014] As a further preferred embodiment of the present application, the mass ratio of the wheat bran to the soybean meal is (3-5):(2-3).

[0015] As a further preferred embodiment of the present application, the addition amount of the Paenibacillus polymyxa is 2%-2.5% of the total mass of the wheat bran and the soybean meal.

[0016] In the preparation process of the fermentation material, the water content of the fermentation system is controlled at 55-60%, and after the fermentation is completed, drying treatment is performed to obtain the fermentation material. The preferred drying temperature is 60-65℃.

[0017] The present application also provides a preparation method of the above lactation material, comprising the following steps:

[0018] The raw materials are mixed according to the mass ratio to obtain the lactation material.

[0019] The present application further provides the application of the above lactation material in improving the iron content of sow milk.

[0020] As a further preferred embodiment of the present application, when applied, the lactation material is added to the basic daily feed of sows at an addition amount of 2.5-3.0‰.

[0021] The composite iron source used in the present application can ensure efficient absorption of sows, thereby effectively improving the iron content in milk.

[0022] Eugenol is the main active ingredient of Chinese medicine clove. It is currently found that eugenol has good antibacterial efficacy and is commonly used for the treatment of bacterial or viral diseases in animals, etc. The present application finds that the eugenol and the above fermentation material can be compounded with the composite iron source to effectively promote the improvement of the iron content in sow milk.

[0023] The present application discloses the following technical effects:

[0024] The present application uses specific strains to ferment wheat bran and soybean meal, and the obtained fermentation material, composite iron source and eugenol are compounded to obtain a lactation material. The lactation material can significantly improve the iron content in sow milk during lactation period with a small amount of addition in the daily ration, ensure the iron demand of piglets, improve the survival rate, birth weight and weaning weight of piglets, and ensure the health of piglets. DETAILED DESCRIPTION

[0025] The following detailed description of various exemplary embodiments of the application should not be considered to be limiting of the application, but rather a description of certain aspects, features, and embodiments of the application.

[0026] It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. Additionally, for a range of values of a parameter, unless otherwise indicated, each intervening value by each intervening value, as well as any other stated or intervening value in that stated range is encompassed. The upper and lower limits of these intervening values can independently be included or excluded in the range, and each smaller range that falls within the ambit of the recited ranges is also encompassed. These smaller ranges are not precluded from the scope of the application even though the smaller ranges are not explicitly recited or are not individually singled out.

[0027] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. Although any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present application, the preferred methods and materials are described. All patents, patent applications, publications, and descriptions mentioned herein are incorporated by reference to disclose and describe the methods and / or materials in connection with which the patents, patent applications, publications, and descriptions are cited.

[0028] Many modifications and variations of the present application described in the specification are possible without departing from the scope or spirit of the application. Other implementations of the application will be apparent to those skilled in the art from consideration of the specification and practice of the application disclosed herein. The specification and examples given are exemplary only. It is intended to include all such modifications and variations in the scope of the present application.

[0029] As used herein, the terms "comprises", "comprising", "includes", "including", "has", "having", "contains", "containing", or variations thereof, are intended to be open-ended terms that mean inclusion, but not limited to, the listed materials and methods.

[0030] The Paenibacillus polymyxa used in the embodiments of the application is Paenibacillus polymyxa DYr4.4, with a preservation number of CCTCC M2018023, and is purchased from the China Center for Type Culture Collection.

[0031] Example 1

[0032] The raw materials of the lactation feed in the embodiments of the application include the following components by mass fraction:

[0033] 3 parts of iron source, 7.8 parts of fermentation material, and 1.0 part of eugenol.

[0034] The iron source used is a composite iron source with a mass ratio of 1:1.5:2 of glycine ferrous, methionine ferrous, and fumarate ferrous.

[0035] The preparation process of the fermentation material is as follows:

[0036] The wheat bran and soybean meal are mixed according to a mass ratio of 4:3, then 2% of Paenibacillus polymyxa DYr4.4 is added to the mixture, then water is added to adjust the moisture content to 60%, and fermentation is carried out at 37 DEG C for 48h; after the fermentation is completed, drying (65 DEG C) is carried out to obtain the fermentation material.

[0037] The preparation steps of the lactation material are as follows:

[0038] The raw materials are mechanically mixed according to the mass ratio to obtain the lactation material.

[0039] Example 2

[0040] The raw materials of the lactation material of the embodiment of the present application include the following components in mass parts:

[0041] 3 parts of iron source, 7 parts of fermentation material, and 1.0 part of eugenol.

[0042] The iron source used is a composite iron source with a mass ratio of glycine ferrous, methionine ferrous, and fumarate ferrous of 1:1:2.

[0043] The preparation process of the fermentation material is as follows:

[0044] The wheat bran and soybean meal are mixed according to a mass ratio of 3:2, then 2.5% of Paenibacillus polymyxa DYr4.4 is added to the mixture, then water is added to adjust the moisture content to 60%, and fermentation is carried out at 35 DEG C for 48h; after the fermentation is completed, drying (65 DEG C) is carried out to obtain the fermentation material.

[0045] The preparation steps of the lactation material are as follows:

[0046] The raw materials are mechanically mixed according to the mass ratio to obtain the lactation material.

[0047] Example 3

[0048] The raw materials of the lactation material of the embodiment of the present application include the following components in mass parts:

[0049] 2.5 parts of iron source, 6 parts of fermentation material, and 0.9 part of eugenol.

[0050] The iron source used is a composite iron source with a mass ratio of glycine ferrous, methionine ferrous, and fumarate ferrous of 1:2:2.

[0051] The preparation process of the fermentation material is as follows:

[0052] The wheat bran and soybean meal are mixed according to a mass ratio of 5:3, then 2% of Paenibacillus polymyxa DYr4.4 is added to the mixture, then water is added to adjust the moisture content to 60%, and fermentation is carried out at 37 DEG C for 60h; after the fermentation is completed, drying (60 DEG C) is carried out to obtain the fermentation material.

[0053] The preparation steps of the lactation material are as follows:

[0054] The raw materials are mechanically mixed according to the mass ratio, and then the lactation material is obtained.

[0055] Example 4

[0056] The raw materials of the lactation material in the embodiment of the present application include the following components by mass:

[0057] 2 parts of iron source, 6 parts of fermentation material, and 0.9 parts of eugenol.

[0058] The iron source used is a composite iron source with a mass ratio of glycine ferrous, methionine ferrous, and fumarate ferrous of 1:1:2.

[0059] The preparation process of the fermentation material is as follows:

[0060] The wheat bran and soybean meal are mixed according to a mass ratio of 5:2, then 2% of Bacillus polymyxa DYr4.4 is added to the mixture, then water is added to adjust the moisture content to 60%, and then the mixture is fermented at 35℃ for 48h. After the fermentation is completed, the mixture is dried (65℃) to obtain the fermentation material.

[0061] The preparation steps of the lactation material are as follows:

[0062] The raw materials are mechanically mixed according to the mass ratio, and then the lactation material is obtained.

[0063] Example 5

[0064] The raw materials of the lactation material in the embodiment of the present application include the following components by mass:

[0065] 2.5 parts of iron source, 5 parts of fermentation material, and 0.8 parts of eugenol.

[0066] The iron source used is a composite iron source with a mass ratio of glycine ferrous, methionine ferrous, and fumarate ferrous of 1:1.5:2.

[0067] The preparation process of the fermentation material is as follows:

[0068] The wheat bran and soybean meal are mixed according to a mass ratio of 4:3, then 2% of Bacillus polymyxa DYr4.4 is added to the mixture, then water is added to adjust the moisture content to 55%, and then the mixture is fermented at 37℃ for 60h. After the fermentation is completed, the mixture is dried (65℃) to obtain the fermentation material.

[0069] The preparation steps of the lactation material are as follows:

[0070] The raw materials are mechanically mixed according to the mass ratio, and then the lactation material is obtained.

[0071] Comparative Example 1

[0072] The difference between Example 1 and Comparative Example 1 is that the eugenol is replaced with an equal amount of fermentation material (prepared in Example 1).

[0073] Comparative Example 2

[0074] The difference from Example 1 is that the replacement strain is Bacillus subtilis (the accession number is ACCC-10619).

[0075] Comparative Example 3

[0076] The difference from Example 1 is that the composite iron source is replaced by methionine ferrous single iron source, and the amount of iron source is ensured to be unchanged.

[0077] Effect verification example:

[0078] 1. Experimental object: healthy pregnant sows (pregnant for 85 days) of the same blood relationship, close farrowing performance and parity (3-4 parity) and Duroc crossbred.

[0079] 2. Experimental grouping:

[0080] According to the above standard, 108 experimental sows are selected and randomly divided into a control group, experimental groups 1-5, and control experimental groups 1-3, each group has 12 sows.

[0081] 3. Experimental conditions:

[0082] Control group: fed with basic diet;

[0083] Experimental groups 1-5: on the basis of the basic diet, each group is added with the lactation material of Examples 1-5 (added at an amount of 2.5‰);

[0084] Control experimental groups 1-3: on the basis of the basic diet, each group is added with the lactation material of Comparative Examples 1-3 (added at an amount of 2.5‰);

[0085] The other feeding conditions of each group are the same, and the sows continue to be fed according to the above grouping during the lactation period.

[0086] The basic diet composition of sows during the gestation and lactation period is shown in Table 1.

[0087] 4. Experimental results:

[0088] The iron content in the colostrum and normal milk of each group of sows is determined, and the average data is shown in Table 2.

[0089] The serum iron of each group of lactating sows, newborn piglets and weaned piglets is determined, including serum total iron binding capacity (TIBC) and serum iron content (SI), and the blood physiological indexes of each group of lactating sows, newborn piglets and weaned piglets are tested, including red blood cell (RBC) concentration and hemoglobin (HGB) concentration. The average data is shown in Tables 3-4.

[0090] Table 1

[0091] Raw materials Corn Soybean meal Wheat bran Premix Proportion (%) 65 25 6 4

[0092] Note: premix provides per kg feed: Cu: 8mg; Fe: 70mg; Zn: 90mg; Mn: 20mg; Se: 0.2mg; I2: 0.3mg; Ca: 6g; P: 4g; VA: 4000IU; VE: 40mg; VD3: 2160IU; VK3: 1.7mg; VB1: 2mg; VB2: 5mg; VB6: 1.8mg; VB 12 : 0.02mg; nicotinic acid: 20mg; D-calcium pantothenate: 10mg; folic acid: 1mg; biotin: 0.08mg.

[0093] Table 2

[0094]

[0095] Table 3

[0096]

[0097]

[0098] Table 4

[0099]

[0100] The growth performance data of the piglets in each group are shown in Table 5:

[0101] Table 5

[0102]

[0103] During the experiment, except that 2 piglets in the control group had mild diarrhea, the piglets in the other groups had no diarrhea, and the body health condition was good.

[0104] It can be seen that the lactation material of the present application has reasonable nutrition, can further improve the survival rate and body weight of piglets, and ensure the body health.

[0105] The above-described embodiments are only to describe the preferred modes of the present application, and not to limit the scope of the present application, and under the premise of not departing from the design spirit of the present application, various modifications and improvements of the technical solutions of the present application made by the ordinary skilled in the art shall fall within the protection scope determined by the claims of the present application.

Claims

1. A lactation feed that increases the iron content in sow's milk, characterized in that, The raw materials include the following components in parts by weight: 2-3 parts iron source, 5-8 parts fermentation material, and 0.8-1.0 parts eugenol; The fermentation material is prepared by fermenting wheat bran and soybean meal with Bacillus polymyxa. The iron source is a composite iron source composed of ferrous glycinate, ferrous methionine and ferrous fumarate. The mass ratio of ferrous glycinate, ferrous methionine and ferrous fumarate is 1:(1-2):2; The fermentation temperature is 35-37℃; The fermentation time is 48-60 hours; The polymyxin Bacillus is polymyxin Bacillus DYr4.4; The mass ratio of wheat bran to soybean meal is (3-5):(2-3).

2. The emulsifying agent according to claim 1, characterized in that, The amount of *Bacillus polymyxa* added is 2%-2.5% of the total mass of the wheat bran and soybean meal.

3. The method for preparing the emulsifying agent according to any one of claims 1-2, characterized in that, Includes the following steps: The raw materials are mixed according to the mass ratio to obtain the emulsifying agent.

4. The use of the lactating feed as described in any one of claims 1-2 in the preparation of feed that increases the iron content of sow milk.

5. The application according to claim 4, characterized in that, The lactation feed is added to the sow's basal daily feed at a rate of 2.5-3.0‰.

Citation Information

Patent Citations

  • Composite organic iron formulation

    CN101411398A

  • Composite essential oil premixing agent special for breeding sows and preparation method thereof

    CN106360017A

  • Bacillus polymyxa CPL258 and screening and application thereof

    CN114891678A