Process for the extraction of quinic acid from cranberries

Abstract

The present application relates to plant active ingredient extraction technology, particularly to a method for extracting quinic acid in cranberry, specifically, the method comprises the following steps: crushing the cranberry, mixing the crushed cranberry with water to form a slurry, extracting the slurry under low temperature and ultrasonic wave, filtering the slurry after the extraction is completed to remove solid residues, obtaining a filtrate, adding activated carbon to the filtrate for adsorption, adding a desorption agent to the activated carbon for desorption after the adsorption is completed, obtaining quinic acid extract, concentrating the quinic acid extract, and freeze-drying the concentrated quinic acid extract to obtain quinic acid, the extraction device of the present application has high degree of automation and can improve the crushing effect of the cranberry.

Description

TECHNICAL FIELD

[0001] The present application relates to plant active ingredient extraction technology, in particular to a method for extracting quinic acid in cranberry. BACKGROUND

[0002] Cranberry is a fruit rich in various nutrients, known as "natural antibiotics", has many very high health care effect, among them quinic acid is a traditional Chinese medicine active ingredient in cranberry, has antioxidant, anti-inflammatory, anti-tumor and other biological activities. At present, the method for extracting quinic acid from cranberry is to crush the cranberry and mix it with water, then filter, collect the filtrate, add activated carbon to the filtrate for absorption, add desorption agent after absorption is completed, obtain quinic acid extract, and finally concentrate and dry the quinic acid extract to obtain quinic acid.

[0003] However, the existing technology for extracting quinic acid from cranberry has low automation, and the existing technology for crushing cranberry by the crusher has different sizes of the crushed powder, which affects the extraction of quinic acid, so there is an urgent need for a method for extracting quinic acid from cranberry, which has high automation and improves the crushing effect of cranberry. SUMMARY

[0004] The technical problem to be solved by the present application is to provide a method for extracting quinic acid from cranberry, which has high automation and improves the crushing effect of cranberry.

[0005] In order to solve the above technical problems, the technical scheme adopted by the present application is as follows: a method for extracting quinic acid from cranberry based on an extraction device, comprising:

[0006] A circular tank body, a plurality of through holes are arranged on the outer wall of the circular tank body, a feeding pipe is arranged on the upper part of the circular tank body, and a first electromagnetic valve is arranged on the feeding pipe;

[0007] A raw material box connected with the feeding pipe;

[0008] A stirring device located in the circular tank body, the stirring device comprising a stirring shaft and stirring blades, the stirring shaft being a hollow cavity, a first filter screen being arranged on the outer wall of the stirring shaft, the first filter screen being located between adjacent stirring blades, a plurality of stirring blades being connected to the outer wall of the stirring shaft, and the plurality of stirring blades being distributed in a circular array;

[0009] A first tank body in the shape of a revolution body, the revolution body comprising an upper cylinder and a lower conical body, and the circular tank body being coaxially located in the upper cylinder;

[0010] A driving device for driving the stirring shaft to rotate;

[0011] An air extraction pipe is connected to the upper end of the stirring shaft through a rotary joint;

[0012] An air extraction pump is connected to the air extraction pipe;

[0013] A first discharge pipe is connected to the lower part of the lower cone body, and a second electromagnetic valve is arranged on the first discharge pipe;

[0014] A second tank body is in communication with the first discharge pipe at the upper part, and a microwave generator is arranged on the symmetrical side wall of the second tank body, and a second discharge pipe is arranged on the lower part of the second tank body, and a third electromagnetic valve is arranged on the second discharge pipe;

[0015] A water tank is arranged for placing ice water;

[0016] A water pipe is connected to the water tank at one end, and connected to the second tank body at the other end, and a water pump is arranged on the water pipe;

[0017] A second filter screen is arranged on the second discharge pipe, and below the third electromagnetic valve;

[0018] A third tank body is in communication with the second discharge pipe at the upper part, and the third tank body is provided with a first pipe and a second pipe, the first pipe is used for putting activated carbon, and the second pipe is used for putting desorption agent, a fourth electromagnetic valve is arranged on the first pipe, and a fifth electromagnetic valve is arranged on the second pipe, and a third discharge pipe is arranged on the lower part of the third tank body, and a sixth electromagnetic valve is arranged on the third discharge pipe;

[0019] A collection tank is in communication with the third discharge pipe at the upper part;

[0020] A controller is electrically connected with the first electromagnetic valve, the driving device, the air extraction pump, the microwave generator, the second electromagnetic valve, the third electromagnetic valve, the fourth electromagnetic valve, the fifth electromagnetic valve and the sixth electromagnetic valve;

[0021] A method for extracting quinic acid in cranberry, comprising the following steps:

[0022] Step 1: Put the cranberry into the raw material tank, and the controller controls the first electromagnetic valve to open for a predetermined time, and then controls the first electromagnetic valve to close, and then controls the driving device to open, and the stirring shaft rotates at a first speed for a predetermined time, and then controls the driving device to close;

[0023] Step 2: the controller controls the second electromagnetic valve to open for a preset time, the controller controls the third electromagnetic valve to close, the controller controls the water pump to open, and the controller controls the air pump and the driving device to open at the same time, the stirring shaft rotates at a second speed, the second speed is less than the first speed, and the stirring shaft rotates for a preset time, the controller controls the air pump and the driving device to close, the controller controls the water pump to close, the controller controls the microwave generator to open for a preset time, and the controller controls the microwave generator to close;

[0024] Step 3: the controller controls the third electromagnetic valve to open for a preset time, the controller controls the third electromagnetic valve to close, the controller controls the fourth electromagnetic valve to open for a preset time, the controller controls the fourth electromagnetic valve to close, the controller controls the fifth electromagnetic valve to open for a preset time, and the controller controls the fifth electromagnetic valve to close;

[0025] Step 4: the controller controls the sixth electromagnetic valve to open for a preset time, and the controller controls the sixth electromagnetic valve to close;

[0026] Step 5: the liquid in the collection tank is vacuum concentrated and dried to obtain quinic acid.

[0027] Further, the desorbent is any one of sodium hydroxide, calcium hydroxide or sodium carbonate.

[0028] Further, the driving device comprises a driving motor, a first gear and a second gear, the second gear is coaxially and drivingly connected with the stirring shaft, the first gear is engaged with the second gear, and the driving motor is drivingly connected with the first gear.

[0029] Further, the collection tank is provided with a liquid sensor, the collection tank is provided with a fourth discharge pipe, the fourth discharge pipe is provided with a seventh electromagnetic valve, and the controller is electrically connected with the liquid level sensor and the seventh electromagnetic valve.

[0030] Further, the stirring blade is provided with a guide plate, the stirring blade and the cross section of the stirring shaft form an included angle of 130°-160°, the guide plate and the cross section of the stirring shaft form an included angle of 130°-160°, and the guide plate and the stirring blade form an included angle of 120°-160°.

[0031] Further, the outer wall of the conical body is provided with a vibrator, and the controller is connected with the vibrator.

[0032] The beneficial effects of the present application are that: (1) by providing a through hole on the outer wall of the circular tank, the stirring blades stir the cranberries into cranberry powder, and the cranberry powder falls into the first tank through the through hole, so that the size of the crushed cranberry powder is uniform and the wall breaking effect is good. (2) By accurately controlling the time of the first tank, the second tank and the third tank, the controller makes the whole process of extracting quinic acid continuous. (3) By setting the cross section of the stirring blade and the stirring shaft at an angle of 130°-160° and the cross section of the guide plate and the stirring blade at an angle of 120°-160°, the cranberries can be thrown up while being stirred, and the guide plate guides the cranberries to the through hole of the circular tank. BRIEF DESCRIPTION OF DRAWINGS

[0033] Fig. 1 The structure diagram of the extraction device of the present application;

[0034] Fig. 2 The structure diagram of the stirring device of the extraction device of the present application;

[0035] Fig. 3 The electrical connection diagram of the controller.

[0036] Label explanation:

[0037] 1, circular tank; 11, through hole; 12, feeding pipe; 121, first electromagnetic valve; 2, raw material box; 3, stirring device; 31, stirring shaft; 32, stirring blade; 321, guide plate; 33, rotary joint; 34, first filter screen; 4, first tank; 41, upper cylindrical body; 42, lower conical body; 421, vibrator; 5, driving device; 51, driving motor; 52, first gear; 53, second gear; 6, air suction pipe; 7, air suction pump; 8, first discharge pipe; 81, second electromagnetic valve; 9, second tank; 91, microwave generator; 92, second discharge pipe; 921, third electromagnetic valve; 10, water tank; 101, water pipe; 1011, water pump; 102, second filter screen; 103, third tank; 1031, first pipe; 10311, fourth electromagnetic valve; 1032, second pipe; 10321, fifth electromagnetic valve; 1033, third discharge pipe; 10331, sixth electromagnetic valve; 104, collection tank; 1041, fourth discharge pipe; 10411, seventh electromagnetic valve; 1042, liquid level sensor; 105, controller. DETAILED DESCRIPTION

[0038] In order to explain the technical content, the purpose and the effect of the present application in detail, the following will be explained in combination with the embodiments and the drawings.

[0039] Please refer to Figs. 1 to 3 A method for extracting quinic acid in cranberry based on an extraction device, comprising:

[0040] The outer wall of the circular tank body 1 is provided with a plurality of through holes 11, and the upper portion of the circular tank body 1 is provided with a feeding pipe 12, and the feeding pipe 12 is provided with a first electromagnetic valve 121;

[0041] The raw material box 2 is connected with the feeding pipe 12;

[0042] The stirring device 3 is located in the circular tank body 1, and the stirring device 3 comprises a stirring shaft 31 and stirring blades, the stirring shaft 31 is a hollow cavity, the outer wall of the stirring shaft 31 is provided with a first filter screen 34, the first filter screen 34 is located between adjacent stirring blades 32, a plurality of stirring blades 32 are connected to the outer wall of the stirring shaft 31, and the plurality of stirring blades 32 are distributed in a circumferential array;

[0043] The first tank body 4 is a rotary body, which comprises an upper cylinder 41 and a lower conical body 42, and the circular tank body 1 is coaxially located in the upper cylinder 41;

[0044] The driving device 5 is used for driving the stirring shaft 31 to rotate;

[0045] The exhaust pipe 6 is connected to the upper end of the stirring shaft 31 through a rotary joint 33;

[0046] The exhaust pump 7 is connected to the exhaust pipe 6;

[0047] The first discharge pipe 8 is connected to the lower portion of the lower conical body, and the first discharge pipe 8 is provided with a second electromagnetic valve 81;

[0048] The second tank body 9 is in communication with the first discharge pipe 8 at the upper portion, and the symmetrical side wall of the second tank body 9 is provided with a microwave generator 91, and the lower portion of the second tank body 9 is provided with a second discharge pipe 92, and the second discharge pipe 92 is provided with a third electromagnetic valve 921;

[0049] The water tank 10 is used for placing ice water;

[0050] The water pipe 101 is connected to the water tank 10 at one end, and the other end of the water pipe 101 is connected to the second tank body 9, and the water pipe 101 is provided with a water pump 1011;

[0051] The second filter screen 102 is connected to the second discharge pipe 92, and the filter screen is located below the third electromagnetic valve 921;

[0052] The third tank body 103 is communicated with the second discharge pipe 92 at the upper part, and is provided with a first pipe 1031 for putting activated carbon and a second pipe 1032 for putting desorbent, the first pipe 1031 is provided with a fourth electromagnetic valve 10311, and the second pipe 1032 is provided with a fifth electromagnetic valve 10321, and the lower part of the third tank body 103 is provided with a third discharge pipe 1033 provided with a sixth electromagnetic valve 10331;

[0053] The collecting tank 104 is communicated with the third discharge pipe 1033 at the upper part;

[0054] The controller 105 is electrically connected with the first electromagnetic valve 121, the driving device 5, the air pump 7, the microwave generator 91, the second electromagnetic valve 81, the third electromagnetic valve 921, the fourth electromagnetic valve, the fifth electromagnetic valve 10321 and the sixth electromagnetic valve 10331;

[0055] The method for extracting quinic acid in cranberry includes the following steps:

[0056] Step 1: Put the cranberry into the raw material box 2, the controller 105 controls the first electromagnetic valve 121 to open for a predetermined time, the controller 105 controls the first electromagnetic valve 121 to close, the controller 105 controls the driving device 5 to open, and the stirring shaft 31 rotates at a first speed for a predetermined time, and the controller 105 controls the driving device 5 to close;

[0057] In the above embodiment, the controller 105 is a PLC controller 105, the controller 105 controls the first electromagnetic valve 121 to open for 15 min, the raw material box 2 puts the cranberry into the circular tank body 1, the controller 105 controls the driving device 5 to open, and the stirring device 3 breaks the cranberry in the circular tank body 1, the broken cranberry powder falls into the upper cylinder 41 of the first tank body 4 through the through hole 11 of the circular tank body 1, and falls into the lower conical body 42 from the upper cylinder 41, and is gathered in the lower conical body 42, the broken cranberry powder is uniform in size through the through hole 11, the breaking effect is optimal, and the controller 105 controls the driving device 5 to close for 45 min.

[0058] Step 2: The controller 105 controls the second electromagnetic valve 81 to open for a preset time, the controller 105 controls the second electromagnetic valve 81 to close, at the same time the second electromagnetic valve 81 is closed, the controller 105 controls the water pump 1011 to open, and at the same time the controller 105 controls the air pump 7 and the driving device 5 to open, the stirring shaft 31 rotates at a second speed, the second speed is less than the first speed, for a preset time, the controller 105 controls the air pump 7 and the driving device 5 to close, and at the same time the controller 105 controls the water pump 1011 to close, the controller 105 controls the microwave generator 91 to open for a preset time, and the controller 105 controls the microwave generator 91 to close.

[0059] In the above embodiment, the controller 105 controls the second electromagnetic valve 81 to open for 10 min, so that the cranberry powder in the conical body enters the second tank body 9, the controller 105 controls the second electromagnetic valve 81 to close, the controller 105 controls the water pump 1011 to open for 5 min, and the ice water is injected into the second tank body 9 to mix with the cranberry powder, the controller 105 controls the water pump 1011 to open at the same time as the controller 105 controls the air pump 7 and the driving device 5 to open, the driving device 5 controls the stirring shaft 31 to rotate, the speed of the stirring shaft 31 is slow rotation at this time, the air pump 7 performs air extraction on the circular tank body 1 through the first filter screen 34, so that the circular tank body 1 through hole 11 is not easy to be blocked, and the powder is extracted back into the circular tank body 1, for 5 min, the controller 105 controls the driving device 5 and the air pump 7 to close, and then the operation of step 1 is repeated, at the same time the controller 105 controls the water pump 1011 to close, the controller 105 controls the microwave generator 91 to open, and extraction is performed under low temperature and microwave generator 91, a micro stirring device 3 can be arranged in the second tank body 9, and the cranberry powder and the ice water are extracted under low temperature and ultrasonic wave for 10 min, and then static for 35 min, and the controller 105 controls the microwave generator 91 to close.

[0060] Step 3: The controller 105 controls the third electromagnetic valve 921 to open for a preset time, the controller 105 controls the third electromagnetic valve 921 to close, the controller 105 controls the fourth electromagnetic valve 10311 to open for a preset time, the controller 105 controls the fourth electromagnetic valve 10311 to close, the controller 105 controls the fifth electromagnetic valve 10321 to open for a preset time, and the controller 105 controls the fifth electromagnetic valve 10321 to close.

[0061] In the above embodiment, the controller 105 controls the third electromagnetic valve 921 to open for 10 minutes, so that the solid residues in the liquid in the second tank 9 are retained in the second filter screen 102, and the filtrate enters the third tank 103. The controller 105 controls the third electromagnetic valve 921 to close, and the controller 105 controls the fourth electromagnetic valve 10311 to open for 5 minutes, so that the activated carbon enters the third tank 103. The activated carbon is used to adsorb the filtrate for 1 hour, so that the adsorption liquid rich in quinic acid is obtained. The controller 105 controls the fifth electromagnetic valve 10321 to open for 10 minutes, so that the desorption treatment is performed on the adsorption liquid rich in quinic acid, and the quinic acid extract is obtained. During the adsorption and desorption of the third tank 103, the controller 105 controls the second tank 9 to start the ultrasonic extraction and low-temperature extraction for 10 minutes. When the second tank 9 is emptied, the first tank 4 is still stirring. When the stirring of one tank is completed, the powder in the first tank 4 enters the second tank 9, and the reaction time is 75 minutes. The emptying time of the third tank 103 is exactly 75 minutes. Therefore, when the third tank 103 is completely emptied into the collection tank 104, the reaction of the second tank 9 is completed and enters the third tank 103, so that the reaction processes of the first tank 4, the second tank 9 and the third tank 103 are continuously performed, and the extraction efficiency of quinic acid is improved.

[0062] Step 4: The controller 105 controls the sixth electromagnetic valve 10331 to open for a predetermined time, and the controller 105 controls the sixth electromagnetic valve to close.

[0063] In the above embodiment, the controller 105 controls the sixth electromagnetic valve 10331 to open for 5 minutes, so that the quinic acid extract enters the collection tank 104.

[0064] Step 5: The liquid in the collection tank 104 is vacuum concentrated and dried, so that the quinic acid is obtained.

[0065] As an optional embodiment, the desorption agent is any one of sodium hydroxide, calcium hydroxide or sodium carbonate.

[0066] As an optional embodiment, the driving device comprises a driving motor 51, a first gear 52 and a second gear 53. The second gear 53 is coaxially and drivingly connected with the stirring shaft 31. The first gear 52 is engaged with the second gear 53. The driving motor 51 is drivingly connected with the first gear 52.

[0067] As an optional embodiment, a liquid sensor is arranged in the collection tank. The collection tank 104 is provided with a fourth discharge pipe 1041. The fourth discharge pipe 1041 is provided with a seventh electromagnetic valve 10411. The controller 105 is electrically connected with the liquid level sensor 1042 and the seventh electromagnetic valve 10411.

[0068] In the above embodiment, when the quinic acid extract in the collecting tank 104 reaches the preset height, the liquid level sensor 1042 sends a signal to the controller 105, and the controller 105 controls the seventh electromagnetic valve 10411 to open, so that the quinic acid extract in the collecting tank 104 is taken out for concentration and drying treatment, and the quinic acid is obtained.

[0069] As an optional embodiment, the stirring blade 32 is provided with a guide plate 321, the stirring blade 32 and the cross section of the stirring shaft 31 form an angle of 130°-160°, the guide plate 321 and the cross section of the stirring shaft 31 form an angle of 130°-160°, and the guide plate 321 and the stirring blade 32 form an angle of 120°-160°.

[0070] In the above embodiment, the stirring blade 32 and the cross section of the stirring shaft 31 form an angle of 130°-160°, so that when the cranberries are stirred, the cranberry powder will not gather at the bottom of the circular tank body 1, but will be thrown upward, and the guide plate 321 and the stirring blade 32 form an angle of 120°-160°, so that the cranberries are thrown up at the same time, and the guide plate 321 guides the cranberries to pass through the through hole 11 of the circular tank body 1 by centrifugal force, so as to fall into the first tank body 4.

[0071] As an optional embodiment, the outer wall of the conical body is provided with a vibrator 421, and the controller 105 is connected with the vibrator 421.

[0072] In the above embodiment, the controller 105 controls the vibrator 421, so that the cranberry powder in the conical body falls into the first discharge pipe 8 by vibration, thereby smoothly entering the second tank body 9, and ensuring that the cranberry powder does not stay in the conical body.

[0073] The above only describes the embodiments of the present application, and does not limit the patent scope of the present application, and any equivalent transformation or direct or indirect application in the related technical field according to the content of the specification and drawings of the present application is also included in the patent protection scope of the present application.

Claims

1. A method for extracting quinic acid from cranberries, characterized in that, Based on the extraction device, including: A circular tank has several through holes on its outer wall and a feed pipe at the top, with a first solenoid valve installed on the feed pipe. Raw material bin, which is connected to the feed pipe; The stirring device is located inside the circular tank and includes a stirring shaft and stirring blades. The stirring shaft is a hollow cavity, and a first filter screen is provided on the outer wall of the stirring shaft. The first filter screen is located between adjacent stirring blades. Several stirring blades are connected to the outer wall of the stirring shaft and are arranged in a circumferential array. The first tank body is a rotating body, which includes an upper cylinder and a lower cone. The circular tank body is coaxially located within the upper cylinder. The drive unit is used to drive the stirring shaft to rotate; The air extraction pipe is connected to the upper end of the stirring shaft via a rotary joint. An air pump, which is connected to an air extraction pipe; The first discharge pipe is connected to the lower part of the lower cone, and a second solenoid valve is provided on the first discharge pipe; The second tank has an upper part connected to the first discharge pipe, a microwave generator is provided on the symmetrical side wall of the second tank, a second discharge pipe is provided at the lower part of the second tank, and a third solenoid valve is provided on the second discharge pipe. Water tank, used to hold ice water; A water pipe, one end of which is connected to a water tank and the other end of which is connected to a second tank, with a water pump installed on the water pipe; The second filter screen is connected to the second discharge pipe and is located below the third solenoid valve. The third tank is connected to the second discharge pipe at its upper part. The third tank is equipped with a first pipe and a second pipe. The first pipe is used to add activated carbon, and the second pipe is used to add desorbent. The first pipe is equipped with a fourth solenoid valve, and the second pipe is equipped with a fifth solenoid valve. The lower part of the third tank is equipped with a third discharge pipe, and the third discharge pipe is equipped with a sixth solenoid valve. The collection tank is connected to the third discharge pipe at its upper part. The controller is electrically connected to the first solenoid valve, the drive device, the air pump, the microwave generator, the second solenoid valve, the third solenoid valve, the fourth solenoid valve, the fifth solenoid valve, and the sixth solenoid valve. The method for extracting quinic acid from cranberries includes the following steps: Step 1: Place cranberries into the raw material box. The controller opens the first solenoid valve for a preset time. Then, the controller closes the first solenoid valve and starts the drive device. The stirring shaft rotates at the first speed for a preset time. Finally, the controller stops the drive device. Step 2: The controller controls the second solenoid valve to open for a preset time. Then, the controller controls the second solenoid valve to close. At the same time as the second solenoid valve closes, the controller controls the water pump to start, and simultaneously controls the air pump and drive device to start. The stirring shaft rotates at a second speed, which is less than the first speed, for a preset time. Then, the controller controls the air pump and drive device to close, and simultaneously controls the water pump to close. The controller controls the microwave generator to start for a preset time, and then controls the microwave generator to close. Step 3: The controller controls the third solenoid valve to open for a preset time, then controls the third solenoid valve to close, the controller controls the fourth solenoid valve to open for a preset time, then controls the fourth solenoid valve to close, and the controller controls the fifth solenoid valve to open for a preset time, then controls the fifth solenoid valve to close. Step 4: The controller opens the sixth solenoid valve and continues for a preset time, then the controller closes the sixth solenoid valve. Step 5: Vacuum concentrate and dry the liquid in the collection tank to obtain quinic acid.

2. The method for extracting quinic acid from cranberries according to claim 1, characterized in that, Desorption The additive is any one of sodium hydroxide, calcium hydroxide, or sodium carbonate.

3. The method for extracting quinic acid from cranberries according to claim 1, characterized in that, drive The device includes a drive motor, a first gear and a second gear. The second gear is coaxially connected to the stirring shaft for transmission. The first gear meshes with the second gear, and the drive motor is connected to the first gear for transmission.

4. The method for extracting quinic acid from cranberries according to claim 1, characterized in that, collect The tank is equipped with a liquid sensor, and the collection tank is equipped with a fourth discharge pipe. The fourth discharge pipe is equipped with a seventh solenoid valve, and the controller is electrically connected to the liquid level sensor and the seventh solenoid valve.

5. The method for extracting quinic acid from cranberries according to claim 1, characterized in that, The stirring blades are equipped with guide plates. The stirring blades and the cross-section of the stirring shaft form an angle of 130°-160°. The guide plates and the cross-section of the stirring shaft form an angle of 130°-160°. The guide plates and the stirring blades form an angle of 120°-160°.

6. The method for extracting quinic acid from cranberries according to claim 1, characterized in that, The outer wall of the cone is equipped with a vibrator, and the controller is connected to the vibrator.

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