A composition with the effects of whitening and removing acne marks, its preparation method and its application

Abstract

The present invention relates to the technical field of cosmetic raw materials, and specifically discloses a composition with the effects of whitening and removing acne marks, a preparation method thereof, and an application thereof. The composition with the effects of whitening and removing acne marks comprises the following components in parts by mass: 21.5 - 23.5 parts of a solvent; 1.8 - 2.2 parts of a penetration enhancer; 0.4 - 0.6 parts of a stabilizer; 0.9 - 1.1 parts of an emulsifier; 56.6 - 63.4 parts of a composite extract; 12.3 - 15.7 parts of a skin conditioner; and the composite extract is a compound of centella asiatica extract, white willow bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract. The present invention has the advantages of further improving the whitening and acne-removing effects of cosmetics.

Description

Technical Field

[0001] The present invention relates to the field of cosmetic raw materials, and in particular to a composition with the effects of whitening and removing acne marks, a preparation method thereof, and an application thereof. Background Art

[0002] Cosmetics are one of the important products for skin repair. With the development of technology, cosmetics are no longer luxury goods but have become mass consumer goods with a large consumer group. Therefore, the large consumer group has also brought about the diversity of skin problems, and targeted solutions to skin problems are the development direction of cosmetics.

[0003] Acne is mainly a skin problem caused by the accumulation of oil in skin hair follicles, which leads to the growth of bacteria. After acne subsides, it is also easy to leave acne marks on the skin, seriously affecting the appearance. With the acceleration of the social rhythm, modern young people have a relatively high frequency of acne, resulting in the urgent need for the effects of acne removal, whitening, and acne mark removal among the vast number of consumers.

[0004] Existing cosmetics will add whitening ingredients and antibacterial ingredients to obtain certain acne removal and whitening effects. However, both their whitening effect and acne removal effect are relatively average, with slow results and it is difficult to meet the needs of consumers. Therefore, there is still room for improvement. Summary of the Invention

[0005] In order to further improve the whitening and acne removal effects of cosmetics, the present application provides a composition with the effects of whitening and removing acne marks, a preparation method thereof, and an application thereof.

[0006] In the first aspect, the present application provides a composition with the effects of whitening and removing acne marks, adopting the following technical solution:

[0007] A composition with the effects of whitening and removing acne marks, comprising the following components in parts by mass:

[0008] Solvent 21.5 - 23.5 parts;

[0009] Penetration enhancer 1.8 - 2.2 parts;

[0010] Stabilizer 0.4 - 0.6 parts;

[0011] Emulsifier 0.9 - 1.1 parts;

[0012] Compound extract 56.6 - 63.4 parts;

[0013] Skin conditioner 13.3 - 20.7 parts;

[0014] The compound extract is a compound of centella asiatica extract, white willow bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract.

[0015] By adopting the above technical solution, through the compounding of centella asiatica extract, salix alba bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract, various active ingredients can cooperate with each other to achieve a significant whitening effect, and have a very significant inhibitory effect on propionibacterium acnes, achieving good whitening and acne-removing effects. Moreover, after various active ingredients cooperate with each other, they can also effectively inhibit the activity of elastase, enabling the skin to better restore elasticity, so that the acne marks can be quickly repaired after the acne disappears, making the skin smooth and flat, well meeting the needs of consumers.

[0016] Preferably, the mass ratio of the centella asiatica extract, salix alba bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract is 2.8 - 3.2:24 - 26:14 - 16:14 - 16:1.8 - 2.2.

[0017] By adopting the above technical solution, by specifically selecting the mass ratio of the centella asiatica extract, salix alba bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract, various active ingredients are combined in a specific ratio, resulting in a better synergistic effect, more significant whitening, acne-removing, and acne mark-removing effects, and faster results.

[0018] Preferably, the skin conditioner is a compound of mandelic acid, niacinamide, α-arbutin, betaine, and raspberry ketone glucoside.

[0019] By adopting the above technical solution, by adding mandelic acid, niacinamide, α-arbutin, betaine, and raspberry ketone glucoside, the whitening effect can be further improved, making the skin whitening effect better.

[0020] Preferably, the mass ratio of the mandelic acid, niacinamide, α-arbutin, betaine, and raspberry ketone glucoside is 3.5 - 4.5:2.5 - 3.5:0.8 - 1.2:5.5 - 6.5:1 - 5.

[0021] By adopting the above technical solution, by specifically selecting the mass ratio of the mandelic acid, niacinamide, α-arbutin, betaine, and raspberry ketone glucoside, the whitening effect is further enhanced, and the results are faster.

[0022] Preferably, the solvent is a compound of deionized water and isopentyl glycol.

[0023] By adopting the above technical solution, by specifically selecting the solvent as a compound of deionized water and isopentyl glycol, the solubility of each component in the solvent is relatively high, the product quality is uniform, and the synergistic effect of each component can be better exerted, resulting in better whitening, acne-removing, and acne mark-removing effects.

[0024] Preferably, the mass ratio of the deionized water to the isoprene glycol is 17-18:4.5-5.5.

[0025] By adopting the above technical solution and specifically selecting the mass ratio of deionized water and isoprene glycol, the solubility of the solvent is higher, the raw materials are better and more fully mixed, and the synergistic effect is better.

[0026] Preferably, the penetration enhancer is lauroyl azolam, the stabilizer is p-hydroxyacetophenone, and the emulsifier is decyl glucoside.

[0027] By adopting the above technical solution and specifically selecting lauroyl azetidine as the penetration enhancer, parahydroxyacetophenone as the stabilizer, and decyl glucoside as the emulsifier, the product quality is made more stable and easier to be absorbed by the skin, and the product has more significant effects on whitening, removing acne, and removing acne marks on the skin.

[0028] In a second aspect, the present application provides a method for preparing a composition having the efficacy of whitening and removing acne scars, using the following technical solution:

[0029] A preparation method of the above-mentioned composition with the effect of whitening and removing acne scars comprises uniformly mixing a solvent, a penetration enhancer, a stabilizer, an emulsifier, a compound extract, and a skin conditioner to obtain the composition with the effect of whitening and removing acne scars.

[0030] By adopting the above technical solution, the prepared composition with the efficacy of whitening and removing acne scars can achieve the efficacy of rapid whitening, removing acne and removing acne scars, quickly repair the skin, and make the skin white and smooth.

[0031] In a third aspect, the present application provides an application of a composition having the efficacy of whitening and removing acne scars, using the following technical solution:

[0032] An application of the above-mentioned composition with acne scar whitening efficacy, wherein the composition with acne scar whitening efficacy is added to cosmetics to prepare cosmetics with acne scar whitening efficacy, and the mass content of the composition with acne scar whitening efficacy in the cosmetics is 1-5%.

[0033] By adopting the above technical solution, by adding 1-5% of the composition with whitening and acne scar removal effect to cosmetics, the cosmetics can have the effects of rapid whitening, acne removal, and acne scar removal. The product quality is good and the cost is low, which is conducive to promotion.

[0034] In summary, this application has the following beneficial effects:

[0035] 1. Since this application combines Centella asiatica extract, Salix alba bark extract, Phellodendron amurense bark extract, Houttuynia cordata extract, and Rubus idaeus extract, after the various active ingredients cooperate with each other, they can achieve a significant whitening effect, and have a very significant inhibitory effect on Propionibacterium acnes, which can achieve good whitening and acne-removing effects. Moreover, after the various active ingredients cooperate with each other, they can also well inhibit the activity of elastase, enabling the skin to better restore elasticity, so that the acne marks can be quickly repaired after the acne disappears, making the skin return to a flat and smooth state, well meeting the needs of consumers.

[0036] 2. In this application, it is preferably to specifically select the mass ratio of Centella asiatica extract, Salix alba bark extract, Phellodendron amurense bark extract, Houttuynia cordata extract, and Rubus idaeus extract, so that the various active ingredients are combined in a specific ratio, and the effect of exerting synergistic effects is better, and the effects of whitening, acne-removing, and acne mark-removing are more significant, and the effect is faster.

[0037] 3. In this application, it is preferably to add mandelic acid, niacinamide, α-arbutin, betaine, and raspberry ketone glucoside, which can further improve the whitening effect and make the skin whitening effect better. Detailed implementation mode

[0038] The following further elaborates on this application with reference to examples.

[0039] Example 1

[0040] A composition with the effects of whitening and removing acne marks, comprising the following components:

[0041] Solvent, penetration enhancer, stabilizer, emulsifier, compound extract, skin conditioner.

[0042] The solvent is a compound of deionized water and isopentyl glycol.

[0043] Isopentyl glycol is commercially available, CAS number: 2568-33-4.

[0044] The penetration enhancer is laurocapram, which is commercially available, CAS number: 59227-89-3.

[0045] The stabilizer is p-hydroxyacetophenone, which is commercially available, CAS number: 99-93-4.

[0046] The emulsifier is decyl glucoside, which is commercially available, CAS number: 68515-73-1.

[0047] The compound extract is a compound of Centella asiatica extract, Salix alba bark extract, Phellodendron amurense bark extract, Houttuynia cordata extract, and Rubus idaeus extract.

[0048] Centella asiatica extract was purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0049] Salix alba bark extract was purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0050] Phellodendron amurense bark extract was purchased from Ningxia Vanilla Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0051] Houttuynia cordata extract was purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0052] Rubus idaeus extract was purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0053] The skin conditioner is a compound of mandelic acid, niacinamide, α-arbutin, betaine, and glucoside of raspberry ketone.

[0054] Mandelic acid is sourced from the market, CAS number: 90-64-2.

[0055] Niacinamide is sourced from the market, CAS number: 98-92-0.

[0056] α-Arbutin is sourced from the market, CAS number: 84380-01-8.

[0057] Betaine is sourced from the market, CAS number: 107-43-7.

[0058] Glucoside of raspberry ketone is sourced from the market, CAS number: 38963-94-9.

[0059] The preparation method of the composition with the efficacy of whitening and removing acne marks is as follows:

[0060] Step 1), put 4.5 kg of isopentyl glycol, 2.5 kg of niacinamide, 1.8 kg of lauroyl azone, 5.5 kg of betaine, 1 kg of glucoside of raspberry ketone, 3.5 kg of mandelic acid, 0.4 kg of p-hydroxyacetophenone, 0.9 kg of decyl glucoside, and 17 kg of deionized water into an emulsifying pot, heat to 85 °C, rotate at 120 r / min, stir for 15 min, and stir evenly to obtain a premix.

[0061] Step 2), cool the premix to 40 °C, then add 1.8 kg of Rubus idaeus extract, 0.8 kg of α-arbutin, 2.8 kg of Centella asiatica extract, 24 kg of Salix alba bark extract, 14 kg of Phellodendron amurense bark extract, and 14 kg of Houttuynia cordata extract, rotate at 60 r / min, stir for 30 min, and stir evenly to obtain the composition with the efficacy of whitening and removing acne marks.

[0062] Example 2

[0063] A composition with the efficacy of whitening and removing acne marks, comprising the following components:

[0064] Solvent, penetration enhancer, stabilizer, emulsifier, compound extract, skin conditioner.

[0065] The solvent is a compound of deionized water and isopentyl glycol.

[0066] Isopentyl glycol is commercially available, CAS number: 2568 - 33 - 4.

[0067] The penetration enhancer is laurocapram, commercially available, CAS number: 59227 - 89 - 3.

[0068] The stabilizer is p - hydroxyacetophenone, commercially available, CAS number: 99 - 93 - 4.

[0069] The emulsifier is decyl glucoside, commercially available, CAS number: 68515 - 73 - 1.

[0070] The compound extract is a compound of centella asiatica extract, white willow bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract.

[0071] The centella asiatica extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., water - soluble extract, extraction ratio 10:1.

[0072] The white willow bark extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., water - soluble extract, extraction ratio 10:1.

[0073] The phellodendron amurense bark extract is purchased from Ningxia Vanilla Biotechnology Co., Ltd., water - soluble extract, extraction ratio 10:1.

[0074] The houttuynia cordata extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., water - soluble extract, extraction ratio 10:1.

[0075] The raspberry extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., water - soluble extract, extraction ratio 10:1.

[0076] The skin conditioner is a compound of mandelic acid, niacinamide, α - arbutin, betaine, and raspberry ketone glucoside.

[0077] Mandelic acid is commercially available, CAS number: 90 - 64 - 2.

[0078] Niacinamide is commercially available, CAS number: 98 - 92 - 0.

[0079] α - arbutin is commercially available, CAS number: 84380 - 01 - 8.

[0080] Betaine is commercially available, CAS No.: 107-43-7.

[0081] Raspberry ketone glucoside is commercially available, CAS No.: 38963-94-9.

[0082] The preparation method of the composition with the efficacy of whitening and removing acne marks is as follows:

[0083] Step 1), Put 5 kg of isopentyl glycol, 3 kg of niacinamide, 2 kg of laurocapram, 5 kg of betaine, 2.5 kg of raspberry ketone glucoside, 4 kg of mandelic acid, 0.5 kg of p-hydroxyacetophenone, 1 kg of decyl glucoside, and 17.5 kg of deionized water into an emulsifying pot, heat to 90 °C, rotate at 120 r / min, stir for 15 min, and stir evenly to obtain a premix.

[0084] Step 2), Cool the premix to 44 °C, then add 2 kg of raspberry extract, 1 kg of α-arbutin, 3 kg of centella asiatica extract, 25 kg of white willow bark extract, 15 kg of phellodendron amurense bark extract, and 15 kg of houttuynia cordata extract, rotate at 60 r / min, stir for 30 min, and stir evenly to obtain the composition with the efficacy of whitening and removing acne marks.

[0085] Example 3

[0086] A composition with the efficacy of whitening and removing acne marks, comprising the following components:

[0087] Solvent, penetration enhancer, stabilizer, emulsifier, compound extract, skin conditioner.

[0088] The solvent is a compound of deionized water and isopentyl glycol.

[0089] Isopentyl glycol is commercially available, CAS No.: 2568-33-4.

[0090] The penetration enhancer is laurocapram, which is commercially available, CAS No.: 59227-89-3.

[0091] The stabilizer is p-hydroxyacetophenone, which is commercially available, CAS No.: 99-93-4.

[0092] The emulsifier is decyl glucoside, which is commercially available, CAS No.: 68515-73-1.

[0093] The compound extract is a compound of centella asiatica extract, white willow bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract.

[0094] The centella asiatica extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., water-soluble extract, extraction ratio 10:1.

[0095] The white willow bark extract was purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0096] The phellodendron bark extract was purchased from Ningxia Vanilla Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0097] The houttuynia cordata extract was purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0098] The raspberry extract was purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0099] The skin conditioner is a compound of mandelic acid, niacinamide, α-arbutin, betaine, and raspberry ketone glucoside.

[0100] Mandelic acid is commercially available, CAS number: 90-64-2.

[0101] Niacinamide is commercially available, CAS number: 98-92-0.

[0102] α-Arbutin is commercially available, CAS number: 84380-01-8.

[0103] Betaine is commercially available, CAS number: 107-43-7.

[0104] Raspberry ketone glucoside is commercially available, CAS number: 38963-94-9.

[0105] The preparation method of the composition with the effects of whitening and removing acne marks is as follows:

[0106] Step 1), put 5.5 kg of isopentyl glycol, 3.5 kg of niacinamide, 2.2 kg of lauroyl azone, 6.5 kg of betaine, 5 kg of raspberry ketone glucoside, 4.5 kg of mandelic acid, 0.6 kg of p-hydroxyacetophenone, 1.1 kg of decyl glucoside, and 18 kg of deionized water into an emulsifying pot, heat to 95 °C, rotate at 120 r / min, stir for 15 min, and stir evenly to obtain a premix.

[0107] Step 2), cool the premix to 48 °C, then add 2.2 kg of raspberry extract, 1.2 kg of α-arbutin, 3.2 kg of centella asiatica extract, 26 kg of white willow bark extract, 16 kg of phellodendron bark extract, and 16 kg of houttuynia cordata extract, rotate at 60 r / min, stir for 30 min, and stir evenly to obtain the composition with the effects of whitening and removing acne marks.

[0108] Comparative Example 1

[0109] A composition with the effects of whitening and removing acne marks, compared with Example 2, the difference is only that:

[0110] In the compound extract, the asiatic pennywort extract is replaced with the licorice extract in equal amount.

[0111] The licorice extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0112] Comparative Example 2

[0113] A composition with the effects of whitening and removing acne marks, compared with Example 2, the only difference is that:

[0114] In the compound extract, the white willow bark extract is replaced with the purslane extract in equal amount.

[0115] The purslane extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0116] Comparative Example 3

[0117] A composition with the effects of whitening and removing acne marks, compared with Example 2, the only difference is that:

[0118] In the compound extract, the phellodendron bark extract is replaced with the skullcap root extract in equal amount.

[0119] The skullcap root extract is purchased from Ningxia Vanilla Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0120] Comparative Example 4

[0121] A composition with the effects of whitening and removing acne marks, compared with Example 2, the only difference is that:

[0122] In the compound extract, the houttuynia cordata extract is replaced with the chamomile extract in equal amount.

[0123] The chamomile extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0124] Comparative Example 5

[0125] A composition with the effects of whitening and removing acne marks, compared with Example 2, the only difference is that:

[0126] In the compound extract, the raspberry extract is replaced with the glabrous licorice extract in equal amount.

[0127] The glabrous licorice extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., which is a water-soluble extract with an extraction ratio of 10:1.

[0128] Comparative Example 6

[0129] A composition with the efficacy of whitening and removing acne marks, compared with Example 2, the only difference is that:

[0130] In the compound extract, licorice extract is used to replace centella asiatica extract in equal amount; portulaca oleracea extract is used to replace white willow bark extract in equal amount; scutellaria baicalensis root extract is used to replace phellodendron amurense bark extract in equal amount; chamomile extract is used to replace houttuynia cordata extract in equal amount; glabra licorice root extract is used to replace raspberry extract in equal amount.

[0131] The licorice extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., a water-soluble extract, and the extraction ratio is 10:1.

[0132] The portulaca oleracea extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., a water-soluble extract, and the extraction ratio is 10:1.

[0133] The scutellaria baicalensis root extract is purchased from Ningxia Vanilla Biotechnology Co., Ltd., a water-soluble extract, and the extraction ratio is 10:1.

[0134] The chamomile extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., a water-soluble extract, and the extraction ratio is 10:1.

[0135] The glabra licorice root extract is purchased from Shaanxi Bolin Biotechnology Co., Ltd., a water-soluble extract, and the extraction ratio is 10:1.

[0136] Experiment 1

[0137] A number of volunteers, aged 25 - 35, female, with the initial melanin content in the facial skin between 300 - 400, were recruited. The melanin content was measured using the MX18 melanin tester of CK Company, Germany, and recorded as the initial melanin content.

[0138] Every ten people formed a group, and the test samples prepared from the compositions with the efficacy of whitening and removing acne marks of each example and comparative example were used. It was used 1 time in the morning and evening every day, 3 ml each time. After cleansing the face with disposable facial tissue and clear water, the test sample was evenly applied on the face.

[0139] After continuous use for 15 days, on the morning of the 16th day, after cleansing the face with disposable facial tissue and clear water, the melanin content was measured again using the MX18 melanin tester of CK Company, Germany, and recorded as the melanin content after 15 days of whitening.

[0140] Test sample: 5 g of the composition with the efficacy of whitening and removing acne marks of each example and comparative example and 95 g of deionized water were mixed evenly to prepare the test sample.

[0141] The experimental data of each group were averaged.

[0142] Experiment 2

[0143] The test was conducted in accordance with the test methods for bactericidal performance, antibacterial performance, and stability of products in Appendix C of GB / T 15979-2002 "Hygienic Standard for Disposable Sanitary Products". Test samples were prepared using the compositions with acne scar whitening efficacy of the embodiments and comparative examples. The exposure time was 20 minutes, the test was repeated 10 times, the test temperature was 26.7°C, and the relative humidity was 69%.

[0144] Sample to be tested: 5 g of the composition with the effect of whitening and removing acne scars of each embodiment and comparative example and 95 g of deionized water were mixed uniformly to prepare a sample to be tested.

[0145] Test strain: Propionibacterium acnes, ATCC 11827.

[0146] Experiment 3

[0147] The test samples prepared from the compositions with whitening and acne scar removal effects of the embodiments and comparative examples were subjected to anti-wrinkle and firming effect tests.

[0148] 1. Test Principle

[0149] Biochemical methods for anti-wrinkle and firming efficacy primarily evaluate the inhibitory effect of active substances on elastase to characterize their anti-wrinkle and firming effects. Elastase is the most important enzyme in the matrix metalloproteinase family, primarily synthesized and secreted by fibroblasts. It degrades elastin in the skin, contributing to skin aging.

[0150] 2. Instruments, Equipment, and Reagents

[0151] 2.1 Instruments and equipment:

[0152] Analytical balance;

[0153] Full wavelength multifunctional microplate reader.

[0154] 2.2 Reagents and consumables:

[0155] Tris(hydroxymethyl)aminomethane (AR);

[0156] Concentrated hydrochloric acid (GR);

[0157] elastase (30 U / mg);

[0158] EGCG (epigallocatechin gallate);

[0159] AAAPAN(AR).

[0160] 2.3 Test sample: 5g of the composition with acne scar whitening efficacy of each embodiment and comparative example and 95g of deionized water were mixed evenly to prepare a test sample;

[0161] Negative control: deionized water;

[0162] Positive control: EGCG solution.

[0163] 3. Test method:

[0164] Four groups, namely A, B, C, and D, were set up, with 3 parallels in each group. Buffer solution, sample solution, enzyme solution, and substrate were successively added to a 96-well plate. The 96-well plate was placed in a low-temperature shaking water bath at a certain temperature, and the shaking mode was turned on. After the solution inside reacted completely, the absorbance values of each group were measured at a wavelength of 410 nm.

[0165] 4. Calculation formula

[0166]

[0167] In the formula: A—the absorbance of the reaction solution containing the sample and the enzyme;

[0168] B—the absorbance of the reaction solution containing the sample but without the enzyme;

[0169] C—the absorbance of the reaction solution containing the enzyme but without the sample;

[0170] D—the absorbance of the reaction solution without the sample and the enzyme.

[0171] The specific experimental data of Experiments 1-3 are shown in Table 1.

[0172]

[0173] According to the data comparison of each example and comparative example in Table 1, after 15 days of use in each example, the melanin content was lower than that of each comparative example. It can be seen that each example has a more significant whitening effect and can achieve the effect of rapid whitening.

[0174] The average antibacterial rate of Propionibacterium acnes in each example was higher than that of each comparative example. It can be seen that each example has a stronger antibacterial effect, can quickly sterilize, enable the acne to recover faster, and can achieve the effect of rapid acne treatment.

[0175] The elastase inhibition rate in each example was significantly higher than that of each comparative example. It can be seen that each example can better restore the elasticity of the skin, thus better smoothing the acne marks, and can achieve the effect of rapid acne mark removal.

[0176] In each comparative example, the centella asiatica extract, white willow bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract in the examples were singly or entirely replaced with extracts having whitening and bacteriostatic effects. Since the special compounding system of the centella asiatica extract, white willow bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract was disrupted, the synergistic effect could not be exerted well, resulting in a certain decline in both the whitening and bacteriostatic effects. Moreover, the effect of inhibiting elastase was significantly decreased, making it difficult to achieve the effects of whitening, acne treatment, and acne scar removal simultaneously.

[0177] This specific embodiment is only an interpretation of the present application and does not limit the present application. After reading this specification, those skilled in the art can make modifications without creative contributions to this embodiment as needed, but as long as it is within the scope of the claims of the present application, it is protected by the patent law.

Claims

1. A composition with the efficacy of whitening and removing acne marks, characterized in that: Comprising the following components in parts by mass: 21.5 - 23.5 parts of a solvent; 1.8 - 2.2 parts of a penetration enhancer; 0.4 - 0.6 parts of a stabilizer; 0.9 - 1.1 parts of an emulsifier; 56.6 - 63.4 parts of a compound extract; 13.3 - 20.7 parts of a skin conditioner; The compound extract is a compound of centella asiatica extract, salix alba bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract; The mass ratio of the centella asiatica extract, salix alba bark extract, phellodendron amurense bark extract, houttuynia cordata extract, and raspberry extract is 2.8 - 3.2:24 - 26:14 - 16:14 - 16:1.8 - 2.2; The skin conditioner is a compound of mandelic acid, niacinamide, α - arbutin, betaine, and glucoside of raspberry ketone; The mass ratio of the mandelic acid, niacinamide, α - arbutin, betaine, and glucoside of raspberry ketone is 3.5 - 4.5:2.5 - 3.5:0.8 - 1.2:5.5 - 6.5:1 - 5; The solvent is a compound of deionized water and isopentyl glycol; The mass ratio of the deionized water and isopentyl glycol is 17 - 18:4.5 - 5.5; The penetration enhancer is laurocapram, the stabilizer is p - hydroxyacetophenone, and the emulsifier is decyl glucoside.

2. A preparation method of the composition with the efficacy of whitening and removing acne marks according to claim 1, characterized in that: Mix the solvent, penetration enhancer, stabilizer, emulsifier, compound extract, and skin conditioner evenly to obtain a composition with the efficacy of whitening and removing acne marks.

3. Use of a composition having the efficacy of whitening and removing acne marks according to claim 1, characterized in that: The composition with the efficacy of whitening and removing acne marks is added to cosmetics to prepare cosmetics with the efficacy of whitening and removing acne marks, and the mass content of the composition with the efficacy of whitening and removing acne marks in the cosmetics is 1 - 5%.

Images