Body care composition containing lemon pekoe leaf extract and preparation method of body care composition

Abstract

The invention belongs to the field of daily chemicals. The body care composition comprises the following components in percentage by weight: 0.5%-10% of the lemon-bat hairy-leaf extract, 0.5%-10% of the lemon-bat hairy-leaf extract, 0.5%-10% of the lemon-bat hairy-leaf extract and the balance of water. 0.3%-10% of a lens culinaris seed extract; 0.5%-5% of a centella asiatica extract; 0.3%-1.0% of caffeine; 0.2%-1.0% of sodium salicylate; 0.03% to 0.3% of dipotassium glycyrrhizinate; 0.3% to 1.0% of cyclodextrin; 0.3% to 0.9% of capryloyl glycine; 0.3%-10% of a skin conditioner; 30%-50% of a polyol; and the balance of deionized water. The body care composition containing the lemon pekoe leaf extract is applied to the skin care composition, so that the skin barrier can be repaired, the oil-water balance of the skin can be controlled, the water content of the skin can be increased, excessive grease secretion can be reduced, and the skin can be effectively protected.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of daily chemicals, and particularly relates to a body care composition containing lemon peel leaf extract and a preparation method thereof. BACKGROUND

[0002] The skin of human body contains abundant sebaceous glands, which are the main structures responsible for secreting sebum in the skin. After the cells mature, they will break and release lipids such as cholesterol, fatty acids, wax esters, and squalene, which are transported to the surface of the skin through the pores to form sebum. As a protective layer of the skin, sebum can maintain the normal water-oil homeostasis balance of the skin, help the skin resist external pollutants such as microorganisms and dust, and reduce the damage of external pollutants to the skin.

[0003] However, in modern society, the pace of learning, work and life is fast, and long-term high-pressure state, staying up late, irregular work and rest can easily cause skin secretion disorder, making the skin very sensitive, resulting in dry and tight skin or oily and acne. In addition, sweets in daily diet contain a large amount of sugar, which can stimulate insulin secretion. Long-term intake of a large amount of sugar can destroy the balance of insulin, increase androgen, and then stimulate the secretion of sebaceous glands.

[0004] In order to keep the skin fresh, people often choose to use skin care products to clean the skin oil, but excessive pursuit of the cleaning ability of the product can easily cause negative effects on the human skin. For people with dry skin, their sebaceous glands secrete less, and excessive cleaning can also cause dryness, redness, itching and wrinkle formation. For people with oily skin, excessive cleaning can also damage the normal stratum corneum and break the dynamic balance of the skin, causing the appearance of sensitive skin. In addition, the ordinary skin care cleaning products have insufficient oil control ability after cleaning, and the skin will secrete a large amount of sebum again after a period of time, making the consumer feel uncomfortable. SUMMARY

[0005] The technical problem to be solved by the present application is to provide a body care composition containing lemon peel leaf extract and a preparation method thereof. The body care composition containing lemon peel leaf extract is applied in the skin care composition, which can repair the skin barrier, promote cell renewal, control the oil balance of the skin, improve the skin microenvironment, and effectively protect the skin.

[0006] The technical scheme adopted by the present application to solve the above problems is as follows:

[0007] A body care composition containing lemon balm leaf extract, comprising the following components by weight percentage: lemon balm leaf extract 0.5% to 10%; lentil seed extract 0.3% to 10%; centella asiatica extract 0.5% to 5%; caffeine 0.3% to 1.0%; sodium salicylate 0.2% to 1.0%; dipotassium glycyrrhizinate 0.03% to 0.3%; cyclodextrin 0.3% to 1.0%; capryloyl glycine 0.3% to 0.9%; skin conditioning agent 0.3% to 10%; polyhydric alcohol 30% to 50%; and the balance of deionized water.

[0008] Through the above technical solution, the lemon balm leaf contains rich flavonoids and polyphenols, which can reduce the production of skin oil by protecting squalene from oxidation and reducing sebaceous gland cell differentiation and oil accumulation. In human sebaceous glands, 5α-reductase and aminopeptidase N (APN) can affect the basic metabolic response and cell differentiation process of cells, increasing the production of dihydrotestosterone (DHT). Dihydrotestosterone (DHT) can bind to androgen receptors on sebaceous gland cells, activate DNA replication and protein synthesis, and directly stimulate sebaceous gland hyperplasia and oil secretion. Lemon balm leaf extract can reduce the production of dihydrotestosterone (DHT) by inhibiting 5-α reductase activity, block the androgen signaling pathway, and reduce the activity and oil secretion of sebaceous glands from the source. Lentil seed extract can balance oil secretion in the system with lemon balm leaf extract and shrink skin pores. Caffeine can neutralize free radicals such as superoxide anions and hydroxyl radicals, reduce oxidative stress caused by external environment such as ultraviolet rays and pollutants, protect skin cell DNA and collagen from damage, and caffeine can inhibit the conversion of testosterone to more active dihydrotestosterone (DHT) by 5α-reductase, in cooperation with lemon balm leaf extract and lentil seed extract. Centella asiatica extract has soothing and anti-inflammatory effects, reducing skin redness and itching, and dipotassium glycyrrhizinate also has soothing and anti-inflammatory effects, further reducing skin redness and itching. Sodium salicylate can dissociate into salicylic acid under acidic conditions, has acne and bacteriostatic effects. Capryloyl glycine can reduce skin oil secretion; cyclodextrin has a stabilizing effect on the system.

[0009] Preferably, the body care composition comprises the following components by weight percentage: lemon balm leaf extract 0.5% to 5%; lentil seed extract 0.3% to 5%; centella asiatica extract 0.5% to 4%; caffeine 0.3% to 0.8%; sodium salicylate 0.2% to 0.8%; dipotassium glycyrrhizinate 0.03% to 0.2%; cyclodextrin 0.3% to 0.8%; capryloyl glycine 0.3% to 0.7%; skin conditioning agent 0.3% to 10%; polyhydric alcohol 30% to 50%; and the balance of deionized water.

[0010] More preferably, the body-care composition comprises the following components by weight percentage: lemon balm leaf extract 0.5% to 2.5%; lentil seed extract 0.5% to 2.5%; gota kola extract 0.5% to 2%; caffeine 0.3% to 0.5%; sodium salicylate 0.2% to 0.6%; dipotassium glycyrrhizinate 0.03% to 0.1%; cyclodextrin 0.3% to 0.5%; capryloyl glycine 0.3% to 0.5%; skin conditioning agent 0.3% to 10%; polyol 30% to 50%; and the balance of deionized water.

[0011] Further, the method for preparing the lemon balm leaf extract comprises the following steps:

[0012] A. Clean the lemon balm leaf pieces, dry them at 40-80℃ for 6-10h, and grind them to 20-30 mesh to obtain lemon balm leaf powder;

[0013] B. Mix the lemon balm leaf powder obtained in step A with distilled water at a mass ratio of 1:(10-20), heat to boiling and maintain for 1-3h to obtain a heated mixture;

[0014] C. Centrifuge the heated mixture obtained in step B after cooling to room temperature, the centrifugation speed is 3000-6000rpm, and the time is 20-50min, and take the supernatant;

[0015] D. Treat the supernatant obtained in step C by ultra-low pressure to obtain a concentrated solution, the pressure of the ultra-low pressure treatment is -2 to 0MPa, and the time is 80-120min, freeze-dry the concentrated solution at -25 to -10℃ for 2-7h to obtain a dry powder;

[0016] E. Sterilize the dry powder obtained in step D, dissolve it into a liquid state with a phosphate buffer solution, the mass ratio of the dry powder to the phosphate buffer solution is 1:(1.5-4), and the lemon balm leaf extract is obtained.

[0017] Further, in step E, the sterilization treatment is performed at a temperature of 160-170℃ for 1-2h.

[0018] Preferably, the sterilization treatment is performed using a dry heat sterilizer.

[0019] Further, in step E, the phosphate buffer solution is a disodium hydrogen phosphate / sodium dihydrogen phosphate solution.

[0020] Further, the skin conditioning agent is at least one of betaine, panthenol, sodium PCA, allantoin, pyridoxine, and trehalose.

[0021] The skin conditioner in the composition of the present application has the effect of moisturizing and nourishing as a moisturizing factor.

[0022] Further, the polyhydric alcohol includes at least one of propylene glycol, 1,3-propanediol, 1,2-hexanediol, butanediol, and glycerol.

[0023] Through the above technical solution, the polyhydric alcohol has good solubility and skin permeability, can enhance the stability of the system, is easily absorbed by the skin, the hydrogen bond in the polyhydric alcohol can form a link with water molecules to enhance the skin hydration, reduce the loss of water molecules in the skin, and thus achieve the skin moisturizing effect.

[0024] The present application also provides a preparation method of the body care composition containing lemon peel extract, comprising the following steps:

[0025] S1. Dissolve octanoyl glycine in 80-85℃ hot water, stir until uniform, adjust the pH value to 5.0-6.0 with sodium hydroxide, then add polyhydric alcohol, mix uniformly, and cool to room temperature to obtain material 1;

[0026] S2. Dissolve caffeine and cyclodextrin in 80-85℃ hot water, stir until uniform, and then add the material 1 obtained in step S1 to obtain material 2;

[0027] S3. Dissolve the skin conditioner, glycyrrhizic acid disodium, and sodium salicylate in 80-85℃ hot water respectively, add the skin conditioner solution, glycyrrhizic acid disodium solution, and sodium salicylate solution into the material 2 obtained in step S2 respectively, stir until uniform, and obtain material 3;

[0028] S4. Add the extracted lemon peel extract, lentil seed extract, and centella asiatica extract into the material 3 obtained in step S3 in sequence, stir until uniform, and obtain material 4;

[0029] S5. Measure the pH value of the material 4, and adjust the pH value to 5.0-6.0 with sodium hydroxide;

[0030] S6. After low-temperature aging, filter to obtain the body care composition containing lemon peel extract.

[0031] Further, in step S1, the addition amount of the hot water is 10%-20% of the mass of octanoyl glycine.

[0032] Further, in step S2, the addition amount of the hot water is 10%-20% of the sum of the mass of caffeine and the mass of cyclodextrin.

[0033] Further, in step S3, the mass ratio of the skin conditioner to hot water is 1:(3-5), the mass ratio of glycyrrhizic acid disodium salt to hot water is 1:(4-8), and the mass ratio of sodium salicylate to hot water is 1:(4-8).

[0034] Further, in step S6, the temperature of the low-temperature aging is -15 to -3℃, and the time is 8-18h.

[0035] Further, in step S6, the filtering is performed by using a filter cloth with a mesh size of 50-200.

[0036] The present application has the following advantages:

[0037] 1. The body care composition containing lemon balm leaf extract applied in the skin care composition can not only repair the skin barrier, promote cell renewal, reduce skin damage and external irritation, accelerate the renewal cycle of the scalp, but also inhibit the activity of 5α-reductase, limit the expression of signal molecules, thereby reducing the generation of dihydrotestosterone (DHT), reducing the activity and oil secretion of sebaceous glands, controlling the oil balance of the skin, improving the skin microenvironment, and effectively protecting the skin.

[0038] 2. The lemon balm leaf extract and each component in the composition complement each other and jointly play a role, which can provide more excellent deep cleaning effect, while providing soothing and moisturizing effect, so that the skin is not dry and greasy, and keeps fresh. The lemon balm leaf extract, lentil seed extract, and caffeine have obvious synergistic effect among them, which can increase the anti-aging and antioxidant effect of the body care composition containing lemon balm leaf extract on the skin, and further improve the moisture content of the skin and reduce the excessive secretion of oil.

[0039] 3. The active ingredients of lemon balm leaf are extracted by the ultra-low pressure subcritical extraction method of the present application, which replaces the high-temperature extraction of the traditional extraction method, reduces the damage to the effective components of lemon balm leaf, improves the utilization rate of the effective components in lemon balm leaf, and the extraction method of the present application is good in operability and is conducive to large-scale production. DETAILED DESCRIPTION

[0040] In order to make the technical problems, technical solutions and technical advantages of the present application clearer, specific examples will be described in detail below, but the protection scope of the present application is not limited to the following specific examples. The described examples are only a part of the examples of the present application, but not all the examples, and are not a limitation of the present application. Based on the examples in the present application, all other examples obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

[0041] Unless otherwise defined, all terms used in the description and claims are to be interpreted as is customary in the art. The professional terms used in the present disclosure are used only for the purpose of describing specific embodiments and are not intended to limit the scope of protection of the present disclosure.

[0042] Unless otherwise specified, the various materials, reagents, instruments and equipment used in the present disclosure can be purchased on the market or prepared by existing methods.

[0043] Examples 1 to 4 and Comparative Examples 1 to 2 each provide a body care composition, the components used and the amounts used being shown in Table 1 below, the units being in weight percent.

[0044] Table 1

[0045]

[0046] Specifically, the preparation method of the lemon balm leaf extract comprises the following steps:

[0047] A. Clean the lemon balm leaf pieces, dry them at 60℃ for 8h and grind them to 20-30 mesh to obtain lemon balm leaf powder;

[0048] B. Mix the lemon balm leaf powder obtained in step A with distilled water at a mass ratio of 1:17.5, heat to boiling and maintain for 2h to obtain a heated mixture;

[0049] C. After cooling the heated mixture obtained in step B to room temperature, centrifugal separation is performed at a speed of 3000rpm for 30min, and the supernatant is taken after centrifugation;

[0050] D. The supernatant obtained in step C is treated using an ultra-low pressure vacuum concentrator, the treatment pressure is adjusted to 0MPa, and the treatment time is 100min to obtain a concentrated liquid, which is then freeze-dried at a temperature of -15℃ for 5h to obtain a dry powder;

[0051] E. The dry powder obtained in step C is placed in a dry heat sterilizer, the temperature is set to 160-170℃, and sterilization is performed for 1-2h, after which the sterilized product is dissolved into a liquid state using a disodium hydrogen phosphate / sodium dihydrogen phosphate buffer solution, the mass ratio of the dry powder to the phosphate buffer solution being 1:3, to obtain the lemon balm leaf extract.

[0052] Specifically, the preparation method of the body care composition comprises the following steps:

[0053] S1. Dissolve octanoyl glycine in water at 85℃, the amount of hot water added being 10% of the mass of octanoyl glycine, stir until uniform, adjust the pH to 5.0-6.0 using sodium hydroxide, then add propylene glycol, mix until uniform, and cool to room temperature to obtain material 1;

[0054] S2. Dissolve the caffeine and cyclodextrin with hot water at 85°C, the amount of hot water added is 10% of the total mass of caffeine and cyclodextrin, after stirring evenly, add the material 1 obtained in step S1 into the hot water, to obtain material 2;

[0055] S3. Dissolve the skin conditioner, glycyrrhizic acid disodium salt and sodium salicylate respectively with hot water at 85°C, the mass ratio of skin conditioner to hot water is 1:4, the mass ratio of glycyrrhizic acid disodium salt to hot water is 1:6, the mass ratio of sodium salicylate to hot water is 1:6, add the skin conditioner solution, glycyrrhizic acid disodium salt solution and sodium salicylate solution into the material 2 obtained in step S2 in turn, stir evenly, to obtain material 3;

[0056] S4. Add the lemon balm leaf extract, lentil seed extract and centella asiatica extract into the material 3 obtained in step S3 in turn, stir evenly, to obtain material 4;

[0057] S5. Measure the pH value of the material 4, adjust the pH to 5.0-6.0 with sodium hydroxide;

[0058] S6. After aging at low temperature of 10°C for 12 hours, filter with 150 mesh filter cloth, to obtain the body care composition.

[0059] Apply the body care composition containing lemon balm leaf extract of Example 3 to a conventional bath formula, to prepare Examples 5-7, and the conventional bath formula of the body care composition without lemon balm leaf extract is taken as Comparative Example 7, the specific components and contents are shown in Table 2, in weight percent.

[0060] Table 2

[0061]

[0062]

[0063] Specifically, the preparation method of the above bath formula comprises the following steps:

[0064] A1. Dissolve sodium laureth sulfate with deionized water at 85°C, the amount of deionized water added is 50% of the weight of the above bath formula, then add cocamide MEA and disodium EDTA, stir for 10 min, to obtain material a1;

[0065] A2. Cool the material a1 obtained in step A1 to 45°C, add the body care composition containing lemon balm leaf extract, cocamidopropyl betaine, disodium cocoyl glutamate and phenoxyethanol into the material a1 in turn, stir evenly, to obtain material a2;

[0066] A3. Dissolve sodium benzoate in deionized water at 85°C, the amount of deionized water added is 1.5% of the weight of the above bath formula, and then add the dissolved sodium benzoate into the material body a2 obtained in step A2 to obtain material body a3;

[0067] A4. Adjust the pH of the material body a3 to 5.0-6.0 with citric acid, then add fragrance, and stir for 5-10 min until the material body a3 becomes transparent to obtain material body a4;

[0068] A5. Add viscosity regulator sodium chloride to the material body a4 obtained in step A4 to adjust the viscosity to 5000-7000 cps, and then filter with 100 mesh filter cloth to obtain the finished product.

[0069] Test method:

[0070] The above examples and comparative examples are tested for chicken embryo irritation and oil control effect in human population. The greater the chicken embryo irritation score, the greater the irritation.

[0071] 1. Chicken embryo irritation test method:

[0072] (1) Chicken embryo incubation: newly purchased chicken eggs within 7 days of embryonic age are cleaned on the surface with 70% alcohol, then placed in the incubator with the air chamber facing up, under the conditions of room temperature 20-25°C and relative humidity 45-70%, the incubation temperature is controlled at 37.5°C±0.5°C, and the relative humidity in the incubator is controlled at 50-60%, and continuous incubation is carried out. If the power is cut off during the period, the time should not exceed 2h.

[0073] (2) Sample preparation: if the test sample is a raw material, it should be prepared into a water or vegetable oil solution or suspension according to the maximum use concentration of the raw material; if the test sample is a transparent water-soluble liquid cosmetic product, the test sample should be tested directly in undiluted form, if the test sample is an opaque emulsion or solid cosmetic product, the test sample should be diluted with water or vegetable oil and tested in the form of a transparent solution with the maximum solubility it can achieve. The sample solution should be kept at a constant temperature of 37.5°C±0.5°C for 30 min before testing.

[0074] (3) Control and preparation: if the test sample is diluted with distilled water or vegetable oil, the test should use 0.9% NaCl solution or vegetable oil (such as olive oil, peanut oil) as the solvent control. If other solvents or carriers are used, such solvents / carriers should be used as control substances.

[0075] (4) Chicken Chorioallantoic Membrane Test: The 10-14 day old chicken embryo is drilled with a hand twist drill above the air chamber, a portion of the egg shell is peeled off with a curved tip forceps, the white egg membrane is exposed, 2 mL of 0.9% NaCl solution is added to the egg membrane with a dropper to wet the egg membrane, and the 0.9% NaCl solution is poured out. The inner membrane is carefully removed with a forceps to ensure that the blood vessel membrane is not damaged. A Teflon O-ring is placed on the chicken chorioallantoic membrane, and 30 uL of the test sample solution is added to the Teflon O-ring with a micro-sampler. At this time, the test starts, the egg shell gap is sealed with plastic wrap, and the chicken embryo is placed in a hatching box at 37.5°C ± 0.5°C and continues to incubate for 30 min.

[0076] (5) Result observation: After the chicken embryo is incubated for 30 min, the chicken embryo is taken out of the incubator, the plastic wrap is removed, and the excess egg shell is peeled off to increase the field of view of the chicken chorioallantoic membrane. Under auxiliary lighting (a flashlight can be used for reference), the changes in the blood vessels of the chicken chorioallantoic membrane inside and outside the ring are observed and compared, and the damage to the blood vessels inside the ring is evaluated. If necessary, take pictures to record the changes in the blood vessels of each chicken embryo. The test using the endpoint evaluation method should calculate the endpoint score (ES), and the result is kept to two decimal places: the score of each chicken embryo is equal to the sum of the degree of bleeding, coagulation and vascular resolution observed for each chicken embryo; ES is equal to the mathematical sum of the scores of 6 chicken embryos divided by the average score of 6.

[0077] Table 3 is the result evaluation of the endpoint score method

[0078] Table 3

[0079]

[0080]

[0081] 2. Human population oil control test method:

[0082] (1) 30 qualified male volunteers are selected to test the sample of Example 1 together, and then test the sample of Example 2 together, and so on. The forehead is selected as the test site, and the test area is selected symmetrically on the test site. The test site cannot be used with external drugs for 2-3 days before testing.

[0083] (2) After screening into the group, the subjects need to clean the forehead with clean water, wipe off the water with dry facial tissues, sit quietly in a room that meets the environmental requirements for 10 min, and do not drink water or beverages during this period. The test site is exposed and kept relaxed.

[0084] (3) The skin oil of the subject is tested with a Sebumeter skin oil test probe as the basic skin oil value.

[0085] (4) Use the sample: 0.18 g of the sample is evenly applied to the sample area on the forehead, and massaged until foaming and then rinsed off.

[0086] (5) Post-application data collection: Time the start of the application and measure the forehead skin oil value at 6 hours. The test method is the same as the baseline skin oil value test method, and the test of the same subject must be completed by the same tester using the same instrument. The test probe should be cleaned between measurements.

[0087] (6) Change from baseline: [(Post-application mean - Pre-application mean) / Pre-application mean] * 100%.

[0088] 3. Skin moisture change rate test

[0089] (1) Corneometer CM 825 test principle: The skin corneous layer moisture content test probe uses the capacitance method to measure the moisture content of the human skin corneous layer. It is based on the significant difference in the dielectric constant of water (81) and other substances (<7). According to the difference in the moisture content of the skin corneous layer, the measured capacitance value of the skin is different, and its parameter can represent the moisture content of the skin corneous layer.

[0090] (2) Recruit 10 subjects to test the samples of Example 1 together, then test the samples of Example 2 together, and so on. The subjects need to clean their hands and forearms uniformly, cannot touch water 3 hours before the test, and cannot use any samples (cosmetics or external drugs) on the test site 3 days before the test.

[0091] (3) The cleaning method is to wipe clean with dry facial tissues; the subjects should mark the test area on the inner side of their forearms, and the test area should be 3*3 cm in size.

[0092] (4) Before the test, the subjects should sit quietly in the laboratory at a temperature of 20-22°C and a relative humidity of 40-60% for at least 30 minutes, cannot drink water or beverages, expose their forearms, and place them in a test state, keeping relaxed.

[0093] (5) Measure the baseline value of the sample area to screen.

[0094] (6) Application (application site, application amount, application method): After wetting the skin, take an appropriate amount of sample and apply it to the sample area in 10 circles. Rinse with clean water, press gently with a lint-free paper towel, and absorb the surface moisture.

[0095] (7) After using the sample: Measure the sample area at 6 hours after application.

[0096] (8) Change from baseline: [(Post-application mean - Pre-application mean) / Pre-application mean] * 100%.

[0097] 4. Foam height

[0098] Preheat the super constant temperature instrument to (40±1) °C, and make the Ross foam instrument constant at (40±1) °C. Respectively, take 2.5 g of the sample of the examples and the comparative examples, dissolve in 900 ml of distilled water, and then add 100 ml of hard water of 1500 mg / kg, heat to (40±1) °C. Stir to dissolve the sample uniformly, use a 200 ml measuring funnel to take part of the test solution, and rinse along the wall pipe of the foam instrument. Then take the test solution to the bottom of the foam instrument to the standard scale 50 mL, fill the test solution with a 200 ml measuring funnel, fix the center position of the funnel, and immediately record the foam height. Take the average value of the results within the allowable range as the final result, and the result is retained to the integer bit.

[0099] 5. Facial pore test

[0100] 1. Test instrument and principle: The skin surface texture analyzer (Visioscan VC20 plus) takes images of the skin surface through a skin scope composed of a uniform annular ultraviolet light (UVA) illumination light source and a black and white high-resolution CCD camera. The images are transmitted to the host computer for digital processing. The images are displayed in 256 black and white gray levels. The number of pores at each time point is analyzed by the skin texture image, and the pixel area of each pore can be converted into actual area data.

[0101] 2. Test environment requirements: Temperature: 21.0±1.0℃; Humidity: 50%±10% RH.

[0102] 3. Recruit 10 subjects, and test them with the sample of Example 1 together, and then test them with the sample of Example 2 together, and so on. Before using the sample and before testing, the subjects sit in the laboratory at a temperature of 21±1℃ and a relative humidity of 50%±10% RH for at least 10 minutes, cannot drink water and beverages, expose the face, and keep relaxed; measure the initial value of the sample area, and record the data as 0d.

[0103] 4. Sample application: Apply an appropriate amount of test sample to the sample area, wait for 15-20 minutes, remove the excess material, wash clean, and dry with a dry and debris-free washcloth, and use the sample 6 times (D1, D3, D6, D9, D12, D14) in 14 days.

[0104] 5. After using the product: Measure the number and area of pores in the sample area at the same time as the initial value (9:00-11:00), immediately after using the sample, and on the 14th day after using the sample.

[0105]

[0106] 6. Process the data through the data processing software.

[0107] ​Self-after rate of change: [(post-application mean - pre-application mean) / pre-application mean] * 100%.

[0108] The test results are shown in Tables 4-5.

[0109] Table 4

[0110]

[0111] From the test results of Examples 1-4, it can be seen that the body care composition containing lemon peel extract has less irritation and has a mild effect. From the change in skin oil, the body care composition containing lemon peel extract has a significant oil control effect and can well regulate the secretion of oil by skin sebaceous gland cells. The preferred addition concentration of lemon peel extract is 0.5-2.0%, and further increasing the addition amount has limited effect on oil control and other effects.

[0112] From the comparison of the test results of Example 3 and Comparative Examples 1-6, it can be seen that compared to any one or two of lemon peel extract, pea seed extract, and caffeine added alone, the simultaneous addition of lemon peel extract, pea seed extract, and caffeine can significantly improve the oil control and moisturizing ability of the composition of the present application, indicating that the three components have a synergistic effect, and together inhibit the secretion of skin oil, enhance the oil control effect, and enhance the skin moisturizing effect.

[0113] Table 5

[0114]

[0115] From the test data of Examples 5-7 and Comparative Example 7, it can be seen that lemon peel extract has good compatibility in the system and does not inhibit the foam of the system. At the same time, the addition of lemon peel extract can greatly reduce the irritation of the system and improve the mildness of the system. After using the product containing lemon peel extract, the amount of oil secreted by the skin sebaceous glands is significantly reduced, has a significant oil control effect of at least 6h, and can shrink pores. The blank control sample without the addition of lemon peel extract has higher irritation and less obvious change in oil, indicating that the oil control ability is weak and has no effect on shrinking pores.

[0116] The body care composition containing lemon peel extract can be applied to the formulation of a bath composition, which can improve the state of the body skin, reduce the unhealthy state of the body skin, regulate the water-oil balance of the skin, moisturize and soothe, reduce the secretion of skin oil, and improve the oil secretion of the body skin. The components in the body care composition containing lemon peel extract are complementary and can play a role together, can relieve skin discomfort, redness, itching, and other symptoms, and make the body skin clean and fresh.

[0117] The preferred embodiments of the present application are described in detail above, but the present application is not limited to the specific details of the above-described embodiments, and various simple modifications can be made to the technical solutions of the present application within the technical concept of the present application, and these simple modifications all belong to the protection scope of the present application.

[0118] In addition, it should be noted that each specific technical feature described in the above specific embodiments can be combined in any appropriate manner without contradiction. In order to avoid unnecessary repetition, various possible combinations are not described again by the present application.

[0119] In addition, various different embodiments of the present application can also be combined in any manner, as long as it does not deviate from the idea of the present application, and it should also be considered as disclosed by the present application.

Claims

1. A body care composition comprising an extract of lemon balm leaves, characterized in that, A body care composition comprising the following components by weight percentage: lemon balm leaf extract 0.5% to 10%; lentil seed extract 0.3% to 10%; centella asiatica extract 0.5% to 5%; caffeine 0.3% to 1.0%; sodium salicylate 0.2% to 1.0%; dipotassium glycyrrhizinate 0.03% to 0.3%; cyclodextrin 0.3% to 1.0%; capryloyl glycine 0.3% to 0.9%; skin conditioning agent 0.3% to 10%; polyhydric alcohol 30% to 50%; and the balance of deionized water.

2. A body care composition containing lemon peel extract according to claim 1, characterized in that, The preparation method of the lemon balm leaf extract comprises the following steps: A. Clean the lemon balm leaf pieces, dry them at 40-80℃ for 6-10h, and crush them to 20-30 mesh to obtain lemon balm leaf powder; B. Mix the lemon balm leaf powder obtained in step A with distilled water at a mass ratio of 1:(10-20), heat to boiling and maintain for 1-3h to obtain a heated mixture; C. Cool the heated mixture obtained in step B to room temperature and centrifuge it at a speed of 3000-6000rpm for 20-50min, and take the supernatant; D. Subject the supernatant obtained in step C to ultra-low pressure treatment to obtain a concentrated solution, the pressure of the ultra-low pressure treatment being -2 to 0MPa and the time being 80-120min, freeze dry the concentrated solution at -25 to -10℃ for 2-7h to obtain a dry powder; E. Sterilize the dry powder obtained in step D, dissolve it in a phosphate buffer solution, and the mass ratio of the dry powder to the phosphate buffer solution being 1:(1.5-4) to obtain the lemon balm leaf extract.

3. A body-care composition containing lemon peel leaf extract according to claim 2, characterized in that, The sterilization temperature is 160-170℃ and the time is 1-2h.

4. A body care composition containing lemon peel extract according to claim 2, characterized in that, The phosphate buffer solution in step E is a sodium phosphate dibasic / sodium phosphate monobasic solution.

5. The body care composition containing lemon peel extract according to claim 1, characterized by, The skin conditioning agent comprises at least one of betaine, panthenol, sodium PCA, allantoin, pyridoxine, and trehalose.

6. A body care composition containing lemon peel extract according to claim 1, characterized in that, The polyhydric alcohol comprises at least one of propylene glycol, 1,3-propanediol, 1,2-hexanediol, butylene glycol, and glycerol.

7. A method for preparing the body-care composition containing the extract of lemon peel leaves according to any one of claims 1 to 6, characterized in that, The preparation method comprises the following steps: S1. Dissolve capryloyl glycine in 80-85℃ hot water, stir until uniform, adjust the pH to 5.0-6.0 with sodium hydroxide, then add polyhydric alcohol, mix until uniform, and cool to room temperature to obtain material 1; S2. Dissolve caffeine and cyclodextrin in 80-85℃ hot water, stir until uniform, and add to the material 1 obtained in step S1 to obtain material 2; S3. Dissolve the skin conditioning agent, dipotassium glycyrrhizinate, and sodium salicylate separately in 80-85℃ hot water, and add the skin conditioning agent solution, dipotassium glycyrrhizinate solution, and sodium salicylate solution respectively to the material 2 obtained in step S2, stir until uniform, and obtain material 3; S4. Add the extracted lemon balm leaf extract, lentil seed extract, and centella asiatica extract successively to the material 3 obtained in step S3, stir until uniform, and obtain material 4; S5. Test the pH of the material 4, and adjust the pH to 5.0-6.0 with sodium hydroxide; S6. After low-temperature aging, filter to obtain the body care composition containing lemon balm leaf extract.

8. The preparation method according to claim 7, characterized in that, The temperature of the low-temperature aging in the step S6 is -15 to -3℃, and the time is 8 to 18 hours. The temperature of the low-temperature aging in the step S6 is -15 to -3℃, and the time is 8 to 18

Images