Compact multipurpose proton beam system

Abstract

The invention discloses a compact multipurpose proton beam system, belongs to the field of radiotherapy, and solves the problem that a treatment terminal of an existing proton beam system is single in type and not compact enough. The superconducting isochronous cyclotron system is connected to the two-way selection system through the beam adjusting system, the two-way selection system comprises a two-way dipole magnet and two branch selection systems, and the two branch selection systems are connected to the rear end of the two-way dipole magnet in parallel. The system also comprises a beam transport system, and the beam transport system is composed of a first treatment terminal section, a second treatment terminal section and a third treatment terminal section. One branch selection system is connected to the fixed experiment beam transport system through the first treatment terminal section, the other branch selection system is connected to the fixed pen-shaped beam transport system through the second treatment terminal section, the third treatment terminal section is a branch of the second treatment terminal section, and the third treatment terminal section is connected to the rotary beam transport system. According to the invention, the beam irradiation of the multi-type and multi-purpose treatment terminal is realized by utilizing the design of a bidirectional selection system.

Description

Technical Field

[0001] The invention belongs to the field of radiotherapy, and in particular relates to a compact multi-purpose proton beam system. Background Art

[0002] The proton therapy system uses proton beams to irradiate tumor lesions. After being accelerated by an accelerator, protons modulate their energy in an energy selection system, and are then transported by a beam transmission system to the treatment terminal before entering the human body. At the beginning of entering the human body, the energy released by proton beams is very limited, but after reaching a certain depth, the beams will instantly release a large amount of energy, forming an energy release trajectory in the shape of a "Bragg peak". Using this feature, proton beams can irradiate tumor lesions with high doses while avoiding normal human tissues. This maximizes the therapeutic effect while reducing the side effects of treatment.

[0003] Aiming at the actual needs of building proton therapy centers in large, medium and small hospitals and scientific research institutions in my country, the proton therapy system can flexibly arrange multiple treatment terminals in a limited space, and reduce the number of transmission line components as much as possible to reduce the cost of the treatment system. A compact and flexible proton therapy beam transmission system that can reduce the number of transmission line components is one of the urgent needs for the widespread construction of proton therapy centers by medical and scientific research institutions in the future.

[0004] The superconducting isochronous cyclotron accelerator supported by superconducting materials has a significantly reduced accelerator diameter and weight, and greatly reduces the power consumption when the accelerator is running. It has obvious advantages in terms of maximum output energy, flux, extraction efficiency, beam emittance, floor space, energy consumption, etc. of the same type of accelerators. It is one of the main accelerator types for the layout of proton therapy systems in future medical or scientific research institutions. In order to further reduce the footprint of the equipment, in addition to the accelerator host, a lightweight rotating beam transport system and a compact fixed pencil beam transport system are also important components of the compact multi-purpose proton therapy system. In addition, in order to meet the potential scientific research needs of medical and scientific research institutions, an independent fixed experimental beam terminal can be reserved to carry out related scientific research projects, and the fixed experimental beam terminal has the potential to be upgraded to a microbeam therapy terminal.

[0005] How to organically combine the fixed experimental beam transport system, the fixed pencil beam transport system and the rotating beam transport system to develop a compact and multi-purpose proton beam system solution that meets the cost expectations and clinical research needs of various institutions is one of the important directions of current research and development of key proton therapy technologies. Summary of the invention

[0006] The purpose of the present invention is to provide a compact multi-purpose proton beam system to solve the problems of the existing proton beam system having a single treatment terminal type, a non-compact layout and high cost.

[0007] The technical solution of the present invention is: a compact multi-purpose proton beam system, comprising an acceleration chamber, a first treatment chamber, a second treatment chamber and a third treatment chamber; a superconducting isochronous cyclotron system is arranged in the acceleration chamber, a fixed experimental beam transport system is arranged in the first treatment chamber, a fixed pencil beam transport system is arranged in the second treatment chamber, and a rotating beam transport system is arranged in the third treatment chamber; The superconducting isochronous cyclotron system is connected to a bidirectional selection system through a beam regulation system. The bidirectional selection system includes a bidirectional dipole magnet and two branch selection systems. The two branch selection systems are connected in parallel at the rear end of the bidirectional dipole magnet. It also includes a beam transport system, which consists of treatment terminal section one, treatment terminal section two and treatment terminal section three; a branch selection system is connected to the fixed experimental beam transport system through treatment terminal section one, and another branch selection system is connected to the fixed pencil beam transport system through treatment terminal section two. Treatment terminal section three is a branch of treatment terminal section two, and treatment terminal section three is connected to the rotating beam transport system.

[0008] As a further improvement of the present invention, the beam adjustment system is provided with a first bidirectional correction magnet of the adjustment system, three first quadrupole magnets of the adjustment system, a second bidirectional correction magnet of the adjustment system, a first vacuum chamber group of the adjustment system, an energy degrader, a collimator, three second quadrupole magnets of the adjustment system, a third bidirectional correction magnet of the adjustment system, and a second vacuum chamber group of the adjustment system in sequence along the proton beam direction.

[0009] As a further improvement of the present invention, the branch selection system is provided with two selection system quadrupole magnets, a momentum selection slit, two selection system quadrupole magnets, and a selection system dipole magnet in sequence along the proton beam direction.

[0010] As a further improvement of the present invention, a section of the treatment terminal is provided with a first vacuum chamber group, a first dipole magnet, a first bidirectional correction magnet, a first quadrupole magnet, a second dipole magnet, three first-stage second quadrupole magnets, a second vacuum chamber group, a second bidirectional correction magnet, two first-stage third quadrupole magnets, a third vacuum chamber group, a third bidirectional correction magnet, two first-stage fourth quadrupole magnets, a fourth vacuum chamber group, and a fourth bidirectional correction magnet in sequence along the proton beam direction.

[0011] As a further improvement of the present invention, the fixed experimental beam transport system is sequentially provided with two experimental beam quadrupole magnets, an experimental beam X-scanning magnet, an experimental beam Y-scanning magnet, an experimental beam measurement system, and experimental beam isocenter points along the proton beam direction.

[0012] As a further improvement of the present invention, the second section of the treatment terminal is provided with two second-section first quadrupole magnets, a second-section first vacuum chamber group, a second-section first bidirectional correction magnet, a second-section first dipole magnet, three second-section second quadrupole magnets, a second-section second dipole magnet, a second-section third quadrupole magnet, a second-section fourth quadrupole magnet, a second-section second vacuum chamber group, and a second second bidirectional correction magnet in sequence along the proton beam direction.

[0013] As a further improvement of the present invention, the fixed pencil beam transport system is sequentially provided with two pencil beam quadrupole magnets, a pencil beam X scanning magnet, a pencil beam Y scanning magnet, a pencil beam measurement system, and a pencil beam isocenter along the proton beam direction.

[0014] As a further improvement of the present invention, the three sections of the treatment terminal are connected to the rear end of the two-section second dipole magnet, and the three sections of the treatment terminal are sequentially arranged along the proton beam direction with two three-section first quadrupole magnets, three-section dipole magnets, three three-section second quadrupole magnets, a three-section vacuum chamber group, and two three-section bidirectional correction magnets.

[0015] As a further improvement of the present invention, the rotating beam transport system is provided with two rotating beam first quadrupole magnets, a rotating beam first dipole magnet and two rotating beam branches in parallel in sequence along the proton beam direction; the rotating beam branches are provided with a rotating beam second quadrupole magnet, a rotating beam third quadrupole magnet, a rotating beam first vacuum chamber group, a rotating beam bidirectional correction magnet, two rotating beam fourth quadrupole magnets, a rotating beam second dipole magnet, a rotating beam second vacuum chamber group, a rotating beam fifth quadrupole magnet, a rotating beam third dipole magnet, a rotating beam X-scanning magnet, a rotating beam Y-scanning magnet, and a rotating beam measurement system in sequence along the proton beam direction; a rotating beam isocenter is provided in the middle of the rotating beam measurement systems of the two rotating beam branches.

[0016] The present invention designs three treatment rooms, in which a fixed experimental beam transport system, a fixed pencil beam transport system and a rotating beam transport system are respectively set up to complete beam transport, realize multi-type active point scanning beam irradiation functions, and adapt to compact building layout. The second and third treatment rooms retain the standard proton therapy beam delivery system to meet the clinical needs of proton therapy; and a longer beam transport space is reserved in front of the first treatment room, that is, the treatment terminal section, and proton beams of different performances can be delivered to the first treatment room by adjusting the magnet setting of the treatment terminal section to meet the diverse needs of clinical and scientific research.

[0017] Compared with the prior art, the present invention has the following advantages: 1. The present invention is based on the proton beam output by a superconducting isochronous cyclotron accelerator. It utilizes a two-way selection system design to provide a fixed experimental beam transport system, a fixed pencil beam transport system and a rotating beam transport system. It can realize the layout of a compact multi-purpose proton beam system. While having the clinical treatment capability of proton radiotherapy, it also takes into account the needs of scientific research and clinical trial projects, and has the potential for equipment upgrade.

[0018] 2. The present invention utilizes high-precision compact beam transmission technology and, through reasonable layout, is compatible with the spatial design of the rotating beam transport system and the fixed pencil beam transport system.

[0019] 3. The present invention makes full use of the beam transmission space and designs a sufficiently long beam transmission line to supply beams to the first treatment room. At the same time, the beam performance parameters can be changed by adjusting and modifying the equipment components on the beam transmission line, which is conducive to carrying out other scientific research projects. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the structure of the present invention; Figure 2 yes Figure 1 A magnified view of part A in FIG. Figure 3 yes Figure 1 A magnified view of part B in FIG. Figure 4 yes Figure 1 The enlarged view of the C part in FIG. Figure 5 It is a schematic diagram of the structure of the fixed experimental beam transport system in the present invention; Figure 6 yes Figure 1 The enlarged view of the D part in FIG. Figure 7 It is a schematic structural diagram of a fixed pencil beam transport system in the present invention; Figure 8 It is a schematic diagram of the structure of the rotating beam transport system in the present invention.

[0021] In the figure: 1-acceleration chamber; 100-superconducting isochronous cyclotron system; 101-the first bidirectional correction magnet of the adjustment system; 102-the first quadrupole magnet of the adjustment system; 105-the second bidirectional correction magnet of the adjustment system; 106-the first vacuum chamber group of the adjustment system; 107-energy degrader; 108-collimator; 109-the second quadrupole magnet of the adjustment system; 112-the third bidirectional correction magnet of the adjustment system; 113-the second vacuum chamber group of the adjustment system; 2-branch selection system; 200-bidirectional dipole magnet; 201-selection system quadrupole magnet; 203-momentum selection slit; 204-selection system quadrupole magnet; 206-selection system dipole magnet; 31-a section of treatment terminal; 3101-a first vacuum chamber group; 3102-a first two-pole magnet; 3103-a first two-way correction magnet; 3104-a first four-pole magnet; 3105-a second two-pole magnet; 3106-a second four-pole magnet; 3109-a second vacuum chamber group; 3110-a second two-way correction magnet; 3111-a third four-pole magnet; 3113-a third vacuum chamber group; 3114-a third two-way correction magnet; 3115-a fourth four-pole magnet; 3117-a fourth vacuum chamber group; 3118-the fourth bidirectional correction magnet of the first section; 32-the second section of the treatment terminal; 3201-the first quadrupole magnet of the second section; 3203-the first vacuum chamber group of the second section; 3204-the first bidirectional correction magnet of the second section; 3205-the first two-pole magnet of the second section; 3206-the second four-pole magnet of the second section; 3209-the second two-pole magnet of the second section; 3210-the third four-pole magnet of the second section; 3211-the fourth four-pole magnet of the second section; 3212-the second vacuum chamber group of the second section; 3213-the second bidirectional correction magnet of the second section; 33-the third section of the treatment terminal; 3301-the first of the third section Quadrupole magnet; 3303-three-section two-pole magnet; 3304-three-section second quadrupole magnet; 3307-three-section vacuum chamber group; 3308-three-section two-way correction magnet; 4-first treatment room; 400-fixed experimental beam transport system; 401-experimental beam quadrupole magnet; 403-experimental beam X-scanning magnet; 404-experimental beam Y-scanning magnet; 405-experimental beam measurement system; 406-experimental beam isocenter; 5-second treatment room; 500-fixed pencil beam transport system; 501-pencil beam quadrupole magnet; 503-pencil Beam X scanning magnet; 504-pencil beam Y scanning magnet; 505-pencil beam measurement system; 506-pencil beam isocenter; 6-third treatment room; 600-rotating beam transport system; 601-rotating beam first quadrupole magnet; 603-rotating beam first dipole magnet; 604-rotating beam second quadrupole magnet; 605-rotating beam third quadrupole magnet; 606-rotating beam first vacuum chamber group; 607-rotating beam bidirectional correction magnet; 608-rotating beam fourth quadrupole magnet; 610-rotating beam second dipole magnet;611-rotating beam second vacuum chamber group; 612-rotating beam fifth quadrupole magnet; 613-rotating beam third two-pole magnet; 614-rotating beam X scanning magnet; 615-rotating beam Y scanning magnet; 616-rotating beam measurement system; 617-rotating beam isocenter. ; DETAILED DESCRIPTION

[0022] The present invention is further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0023] Embodiment 1, like Figure 1-Figure 8 As shown, a compact multi-purpose proton beam system comprises an acceleration chamber 1, a first treatment chamber 4, a second treatment chamber 5 and a third treatment chamber 6; a superconducting isochronous cyclotron system 100 is provided in the acceleration chamber 1, a fixed experimental beam transport system 400 is provided in the first treatment chamber 4, a fixed pencil beam transport system 500 is provided in the second treatment chamber 5, and a rotating beam transport system 600 is provided in the third treatment chamber 6; The superconducting isochronous cyclotron system 100 is connected to a bidirectional selection system through a beam regulating system. The bidirectional selection system includes a bidirectional dipole magnet 200 and two branch selection systems 2. The two branch selection systems 2 are connected in parallel at the rear end of the bidirectional dipole magnet 200. It also includes a beam transport system, which is composed of a treatment terminal section 1 31, a treatment terminal section 2 32 and a treatment terminal section 33; a branch selection system 2 ( Figure 1 The branch selection system 2 on the left side of the middle is connected to the fixed experimental beam delivery system 400 through a treatment terminal section 31, and another branch selection system 2 ( Figure 1 The branch selection system 2) on the middle right is connected to the fixed pencil beam transport system 500 through the treatment terminal section 2 32 , the treatment terminal section 33 is a branch of the treatment terminal section 2 32 , and the treatment terminal section 33 is connected to the rotating beam transport system 600 .

[0024] The beam adjustment system is provided with a first bidirectional correction magnet 101 of the adjustment system, three first quadrupole magnets 102 of the adjustment system, a second bidirectional correction magnet 105 of the adjustment system, a first vacuum chamber group 106 of the adjustment system, an energy degrader 107, a collimator 108, three second quadrupole magnets 109 of the adjustment system, a third bidirectional correction magnet 112 of the adjustment system, and a second vacuum chamber group 113 of the adjustment system in sequence along the proton beam direction.

[0025] The superconducting isochronous cyclotron system 100 can output a proton beam with a maximum energy of 240 MeV.

[0026] The beam regulation system is used to receive a proton beam with a maximum energy of 240 MeV output from the superconducting isochronous cyclotron system 100. By setting a magnet at the front end of the energy degrader 107, the proton beam is in an ideal state before entering the energy degrader 107. Then, by adjusting the energy degrader 107 and the collimator 108 and the subsequent magnet settings, a relatively ideal proton beam with an adjustable target energy between 70-220 MeV can be obtained. Finally, the proton beam is transmitted to the two-way selection system.

[0027] The first vacuum chamber group 106 of the adjustment system is composed of a multi-wire ionization chamber, a Faraday cup and a vacuum box. The multi-wire ionization chamber is used to monitor the beam state in real time when the entire proton beam system is running; the Faraday cup is used to block the proton beam when the entire proton beam system needs to stop the beam; and the vacuum box is used to evacuate to maintain a high vacuum environment for beam transmission.

[0028] The energy degrader 107 adopts a symmetrical wedge structure, and by adjusting the thickness of graphite, the proton beam with a maximum energy of 240 MeV can be reduced to 70-220 MeV according to the treatment terminal requirements.

[0029] The collimator 108 can adjust the emittance of the proton beam at any energy between 70 and 220 MeV output by the energy degrader 107 .

[0030] The second vacuum chamber group 113 of the regulation system is composed of a flux intensity control slit, a Faraday cup, a fluorescent target and a vacuum box. The flux intensity control slit cooperates with the magnetic field adjustment of the front magnet to finely adjust the flux of the proton beam output by the collimator 108 at any energy between 70 and 220 MeV; the Faraday cup is used to monitor the beam intensity information after energy reduction; the fluorescent target is used to monitor the beam state; and the vacuum box is used to evacuate to maintain a high vacuum environment for beam transmission.

[0031] The branch selection system 2 is provided with two selection system quadrupole magnets 201, a momentum selection slit 203, two selection system quadrupole magnets 204, and a selection system dipole magnet 206 in sequence along the proton beam direction. The branch selection system 2 can precisely adjust the momentum dispersion of the proton beam.

[0032] The bidirectional selection system is used to receive a proton beam with a target energy adjustable between 70-220 MeV from the beam adjustment system. Through the action of the bidirectional dipole magnet 200, when the left beam terminal needs to use the beam, the beam is cut to the branch selection system 2 on the left, and then after being focused, restricted, and deflected by the quadrupole magnet, momentum selection slit, and dipole magnet, the momentum dispersion of the proton beam can be accurately adjusted, and after obtaining the proton beam that meets the needs of the left beam terminal, it finally enters the first section 31 of the treatment terminal; when the right beam terminal needs to use the beam, the beam is cut to the branch selection system 2 on the right, and then after being focused, restricted, and deflected by the quadrupole magnet, momentum selection slit, and dipole magnet, the momentum dispersion of the proton beam can be accurately adjusted, and after obtaining the proton beam that meets the needs of the right beam terminal, it finally enters the second section 32 of the treatment terminal.

[0033] The beam transport system consists of treatment terminal section 1 31, treatment terminal section 2 32 and treatment terminal section 33, and is used to transport the proton beam at any energy between 70-220 MeV modulated by the bidirectional selection system to each treatment terminal according to treatment needs.

[0034] A first section 31 of the treatment terminal is provided with a first vacuum chamber group 3101, a first dipole magnet 3102, a first bidirectional correction magnet 3103, a first quadrupole magnet 3104, a second dipole magnet 3105, three second quadrupole magnets 3106, a second vacuum chamber group 3109, a second bidirectional correction magnet 3110, two third quadrupole magnets 3111, a third vacuum chamber group 3113, a third bidirectional correction magnet 3114, two fourth quadrupole magnets 3115, a fourth vacuum chamber group 3117, and a fourth bidirectional correction magnet 3118 in sequence along the proton beam direction.

[0035] A first vacuum chamber group 3101, a second vacuum chamber group 3109, and a third vacuum chamber group 3113 are used for evacuating to maintain a high vacuum environment for beam transmission, and at the same time, installation space for a fluorescent target and a Faraday cage used during debugging is reserved; a fourth vacuum chamber group is used for evacuating, and at the same time, a fluorescent target and a Faraday cage are installed to monitor the beam state and block the proton beam when the beam needs to be stopped, thereby blocking the beam in front of the first treatment room 4.

[0036] The fixed experimental beam transport system 400 is provided with two experimental beam quadrupole magnets 401, an experimental beam X-scanning magnet 403, an experimental beam Y-scanning magnet 404, an experimental beam measurement system 405, and an experimental beam isocenter 406 in sequence along the proton beam direction. The experimental beam X-scanning magnet 403, the experimental beam Y-scanning magnet 404, and the experimental beam measurement system 405 constitute the core components of the fixed experimental beam treatment head, which can realize an active point scanning irradiation field of no less than 30 cm×40 cm, and deliver the proton beam to the experimental beam isocenter 406.

[0037] The second section 32 of the treatment terminal is provided with two second-section first quadrupole magnets 3201, a second-section first vacuum chamber group 3203, a second-section first bidirectional correction magnet 3204, a second-section first dipole magnet 3205, three second-section second quadrupole magnets 3206, a second-section second dipole magnet 3209, a second-section third quadrupole magnet 3210, a second-section fourth quadrupole magnet 3211, a second-section second vacuum chamber group 3212, and a second-section second bidirectional correction magnet 3213 in sequence along the proton beam direction.

[0038] The second-stage first vacuum chamber group 3203 is used for evacuating the vacuum to maintain a high vacuum environment for beam transmission, and at the same time, reserved for the installation space of a fluorescent target and a Faraday cage used during debugging; the second-stage second vacuum chamber group 3212 is used for evacuating the vacuum to maintain a high vacuum environment for beam transmission, and at the same time, a fluorescent target and a Faraday cage are installed to monitor the beam state and block the proton beam when the beam needs to be stopped, thereby blocking the beam in front of the second treatment room 5.

[0039] The fixed pencil beam transport system 500 is provided with two pencil beam quadrupole magnets 501, a pencil beam X scanning magnet 503, a pencil beam Y scanning magnet 504, a pencil beam measurement system 505, and a pencil beam isocenter 506 in sequence along the proton beam direction. The pencil beam X scanning magnet 503, the pencil beam Y scanning magnet 504, and the pencil beam measurement system 505 constitute the core components of the fixed pencil beam treatment head, which can realize an active point scanning irradiation field of no less than 30 cm×40 cm, and deliver the proton beam to the pencil beam isocenter 506.

[0040] The third section 33 of the treatment terminal is connected to the rear end of the second section second dipole magnet 3209. The third section 33 of the treatment terminal is provided with two three-section first quadrupole magnets 3301, three-section dipole magnets 3303, three three-section second quadrupole magnets 3304, three-section vacuum chamber group 3307, and two three-section bidirectional correction magnets 3308 in sequence along the direction of the proton beam. When the third section 33 of the treatment terminal needs to use the beam, the first section 31 of the treatment terminal and the second section 32 of the treatment terminal do not work, and the proton beam from the right branch selection system 2 will pass through the front half of the second section 32 of the treatment terminal and the second section second dipole magnet 3209 to enter the third section 33 of the treatment terminal, and finally arrive in front of the third treatment room 6.

[0041] The three-stage vacuum chamber group 3307 is used for evacuating to maintain a high vacuum environment for beam transmission. It is also equipped with a fluorescent target and a Faraday cage to monitor the beam state and block the proton beam when the beam needs to be stopped, thereby blocking the beam in front of the third treatment room 6.

[0042] The rotating beam transport system 600 is provided with two rotating beam first quadrupole magnets 601, a rotating beam first dipole magnet 603 and two rotating beam branches in parallel in sequence along the proton beam direction; the rotating beam branches are provided with a rotating beam second quadrupole magnet 604, a rotating beam third quadrupole magnet 605, a rotating beam first vacuum chamber group 606, a rotating beam bidirectional correction magnet 607, two rotating beam fourth quadrupole magnets 608, a rotating beam second dipole magnet 610, a rotating beam second vacuum chamber group 611, a rotating beam fifth quadrupole magnet 612, a rotating beam third dipole magnet 613, a rotating beam X-scanning magnet 614, a rotating beam Y-scanning magnet 615 and a rotating beam measurement system 616 in sequence along the proton beam direction; a rotating beam isocenter 617 is provided in the middle of the rotating beam measurement systems 616 of the two rotating beam branches.

[0043] Two rotating beam first quadrupole magnets 601 form the entrance section of the rotating beam transport system 600, which are used to optimize the beam at the entrance and increase the beam spot adjustment capability of the rotating beam transport system 600. The rotating beam first dipole magnet 603, the rotating beam second quadrupole magnet 604, the rotating beam third quadrupole magnet 605, the rotating beam first vacuum chamber group 606, the rotating beam bidirectional correction magnet 607, the rotating beam fourth quadrupole magnet 608, and the rotating beam second dipole magnet 610 form the climbing section of the rotating beam transport system 600, and the climbing height is determined by the scanning irradiation field. The rotating beam first vacuum chamber group 606 and the rotating beam second vacuum chamber group 611 are used for vacuuming, and each is equipped with a fluorescent target for monitoring the beam state. The rotating beam fifth quadrupole magnet 612 is located in the straight transmission section after the climbing section, which is used to optimize the beam after climbing and increase the beam spot adjustment capability of the rotating beam transport system 600. The third rotating beam dipole magnet 613 is a 90-degree deflection dipole magnet, which is used to deflect the proton beam after climbing to the X-scanning magnet 614. The rotating beam transport system 600 can rotate positively and negatively 185 degrees around the rotating beam isocenter 617; the rotating beam X-scanning magnet 614, the rotating beam Y-scanning magnet 615, and the rotating beam measurement system 616 constitute the core components of the rotating beam treatment head, which can achieve an active point scanning irradiation field of no less than 25 cm×25 cm, and distribute the beam to the rotating beam isocenter 617.

[0044] The first treatment room 4, the second treatment room 5, and the third treatment room 6 respectively use a fixed experimental beam transport system 400, a fixed pencil beam transport system 500, and a rotating beam transport system 600 to realize multi-type active point scanning beam irradiation functions and meet the compact functional room layout. In addition, the second treatment room 5 and the third treatment room 6 retain the standard proton therapy beam delivery system to meet the clinical needs of proton therapy; and a longer beam delivery space is reserved in front of the first treatment room 4, that is, the treatment terminal section 31, and proton beams of different performances can be delivered to the first treatment room 4 by adjusting the magnet setting of the treatment terminal section 31 to meet the diverse needs of clinical and scientific research.

[0045] In this embodiment, the equipment layout on the first floor of the proton center of the compact multi-purpose proton beam system occupies an area of ​​less than 1,200 square meters, can provide 3 treatment rooms, and can meet the use of rotating beam and fixed beam proton therapy, and provide a beam transport corridor to meet the needs of scientific research and clinical trial projects.

[0046] In this embodiment, the specifications of the first bidirectional correction magnet 101 of the adjustment system, the second bidirectional correction magnet 105 of the adjustment system, the third bidirectional correction magnet 112 of the adjustment system, a first bidirectional correction magnet 3103, a second bidirectional correction magnet 3110, a third bidirectional correction magnet 3114, a fourth bidirectional correction magnet 3118, a second first bidirectional correction magnet 3204, a second second bidirectional correction magnet 3213, a third bidirectional correction magnet 3308, and a rotating beam bidirectional correction magnet 607 are all C120, and the specific parameters are shown in Table 1.

[0047] In this embodiment, the specifications and models of the first quadrupole magnet 102 of the adjustment system, the second quadrupole magnet 109 of the adjustment system, the quadrupole magnet 201 of the selection system, the quadrupole magnet 204 of the selection system, the first quadrupole magnet 3104 of one section, the second quadrupole magnet 3106 of one section, the first quadrupole magnet 3201 of two sections, the second quadrupole magnet 3206 of two sections, the third quadrupole magnet 3210 of two sections, the first quadrupole magnet 3301 and 3302 of three sections, the third quadrupole magnet 605 of the rotating beam, the fourth quadrupole magnet 608 of the rotating beam, and the fifth quadrupole magnet 612 of the rotating beam are all Q300; the specifications and models of the third quadrupole magnet 3111 of one section, the fourth quadrupole magnet 3115 of one section, the fourth quadrupole magnet 3211 of two sections, the second quadrupole magnet 3304 of three sections, the experimental beam quadrupole magnet 401, the pencil beam quadrupole magnet 501, the first quadrupole magnet 601 of the rotating beam, and the second quadrupole magnet 604 of the rotating beam are all Q150. The specific parameters of the quadrupole magnet are shown in Table 2.

[0048] In this embodiment, the specification model of the bidirectional dipole magnet 200 is DB45; the specification model of the selection system dipole magnet 206, the second-stage first dipole magnet 3205, the second-stage second dipole magnet 3209 and the third-stage dipole magnet 3303 are all B45-1; the specification model of the first-stage dipole magnet 3102 and the second-stage dipole magnet 3105 are all B45-2; the specification model of the first rotating beam dipole magnet 603 and the second rotating beam dipole magnet 610 are all B60; the specification model of the third rotating beam dipole magnet 613 is B90. The specific parameters of the dipole magnets are shown in Table 3.

[0049] The present invention combines a compact beam transmission design, introduces a two-way selection system, and provides a beam transport corridor. The beam transport corridor space can be used to provide a fixed experimental beam transport system 400. At the same time, a standard fixed pencil beam transport system 500 and a rotating beam transport system 600 are provided under limited site conditions, which is conducive to the arrangement of a multi-room multi-purpose proton therapy system in a hospital with limited space.

Claims

1. A compact multi-purpose proton beam system, characterized in that: The invention comprises an acceleration chamber (1), a first treatment chamber (4), a second treatment chamber (5) and a third treatment chamber (6); the acceleration chamber (1) is provided with a superconducting isochronous cyclotron system (100), the first treatment chamber (4) is provided with a fixed experimental beam transport system (400), the second treatment chamber (5) is provided with a fixed pencil beam transport system (500), and the third treatment chamber (6) is provided with a rotating beam transport system (600); The superconducting isochronous cyclotron system (100) is connected to a bidirectional selection system via a beam regulation system. The bidirectional selection system comprises a bidirectional dipole magnet (200) and two branch selection systems (2). The two branch selection systems (2) are connected in parallel at the rear end of the bidirectional dipole magnet (200). It also includes a beam transport system, which is composed of a treatment terminal section 1 (31), a treatment terminal section 2 (32) and a treatment terminal section 3 (33); a branch selection system (2) is connected to a fixed experimental beam transport system (400) through the treatment terminal section 1 (31), and another branch selection system (2) is connected to a fixed pencil beam transport system (500) through the treatment terminal section 2 (32); the treatment terminal section 3 (33) is a branch of the treatment terminal section 2 (32), and the treatment terminal section 3 (33) is connected to a rotating beam transport system (600).

2. A compact multi-purpose proton beam system according to claim 1, characterized in that: The beam regulation system is provided with a first bidirectional correction magnet (101) of the regulation system, three first quadrupole magnets (102) of the regulation system, a second bidirectional correction magnet (105) of the regulation system, a first vacuum chamber group (106) of the regulation system, an energy degrader (107), a collimator (108), three second quadrupole magnets (109) of the regulation system, a third bidirectional correction magnet (112) of the regulation system, and a second vacuum chamber group (113) of the regulation system in sequence along the proton beam direction.

3. A compact multi-purpose proton beam system according to claim 2, characterized in that: The branch selection system (2) is provided with two selection system quadrupole magnets (201), a momentum selection slit (203), two selection system quadrupole magnets (204), and a selection system dipole magnet (206) in sequence along the proton beam direction.

4. A compact multi-purpose proton beam system according to claim 3, characterized in that: The treatment terminal section (31) is provided with a first vacuum chamber group (3101), a first dipole magnet (3102), a first bidirectional correction magnet (3103), a first quadrupole magnet (3104), a second dipole magnet (3105), three second quadrupole magnets (3106), a second vacuum chamber group (3109), a second bidirectional correction magnet (3110), two third quadrupole magnets (3111), a third vacuum chamber group (3113), a third bidirectional correction magnet (3114), two fourth quadrupole magnets (3115), a fourth vacuum chamber group (3117), and a fourth bidirectional correction magnet (3118) in sequence along the proton beam direction.

5. A compact multi-purpose proton beam system according to claim 4, characterized in that: The fixed experimental beam transport system (400) is provided with two experimental beam quadrupole magnets (401), an experimental beam X-scanning magnet (403), an experimental beam Y-scanning magnet (404), an experimental beam measurement system (405), and an experimental beam isocenter (406) in sequence along the proton beam direction.

6. A compact multi-purpose proton beam system according to claim 3, characterized in that: The second section (32) of the treatment terminal is provided with two second-section first quadrupole magnets (3201), a second-section first vacuum chamber group (3203), a second-section first bidirectional correction magnet (3204), a second-section first dipole magnet (3205), three second-section second quadrupole magnets (3206), a second-section second dipole magnet (3209), a second-section third quadrupole magnet (3210), a second-section fourth quadrupole magnet (3211), a second-section second vacuum chamber group (3212), and a second-section second bidirectional correction magnet (3213) in sequence along the proton beam direction.

7. A compact multi-purpose proton beam system according to claim 6, characterized in that: The fixed pencil beam transport system (500) is provided with two pencil beam quadrupole magnets (501), a pencil beam X-scanning magnet (503), a pencil beam Y-scanning magnet (504), a pencil beam measurement system (505), and a pencil beam isocenter (506) in sequence along the proton beam direction.

8. A compact multi-purpose proton beam system according to claim 6, characterized in that: The three sections (33) of the treatment terminal are connected to the rear end of the two-section second dipole magnet (3209), and the three sections (33) of the treatment terminal are provided with two three-section first quadrupole magnets (3301), three-section dipole magnets (3303), three three-section second quadrupole magnets (3304), a three-section vacuum chamber group (3307), and two three-section bidirectional correction magnets (3308) in sequence along the proton beam direction.

9. A compact multi-purpose proton beam system according to claim 8, characterized in that: The rotating beam transport system (600) is provided with two rotating beam first quadrupole magnets (601), a rotating beam first dipole magnet (603) and two rotating beam branches connected in parallel in sequence along the proton beam direction; the rotating beam branches are provided with a rotating beam second quadrupole magnet (604), a rotating beam third quadrupole magnet (605), a rotating beam first vacuum chamber group (606), a rotating beam bidirectional correction magnet (607), two rotating beam fourth quadrupole magnets (608), a rotating beam second dipole magnet (610), a rotating beam second vacuum chamber group (611), a rotating beam fifth quadrupole magnet (612), a rotating beam third dipole magnet (613), a rotating beam X-scanning magnet (614), a rotating beam Y-scanning magnet (615), and a rotating beam measurement system (616) in sequence along the proton beam direction; a rotating beam isocenter (617) is provided in the middle of the rotating beam measurement systems (616) of the two rotating beam branches.

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