Generator for separating yttrium [90Y] in strontium [90Sr]-containing mother liquor and separation method

Abstract

The invention relates to the technical field of isotopes, in particular to a generator for separating yttrium [90Y] in mother liquor containing strontium [90Sr] and a separation method. The separation method comprises the following steps: adding mother liquor containing strontium [90Sr] into a resin separation column, leaching with leacheate, collecting the leacheate containing strontium [90Sr], and emptying liquid in the resin separation column with air; evaporating, dissolving and standing the strontium [90Sr]-containing leacheate at 85-95 DEG C, collecting the strontium [90Sr]-yttrium [90Y] leacheate, and adding the strontium [90Sr]-yttrium [90Y] leacheate into the strontium [90Sr]-containing mother liquor for circulation; and eluting by using an eluent, and collecting the eluent containing yttrium [90Y]. According to the method, the evaporation temperature of the leacheate containing strontium [90Sr] is adjusted, so that the loss of strontium [90Sr] can be greatly avoided, and the separation effect of yttrium [90Y] is not influenced.

Description

Technical Field

[0001] The present invention relates to the field of isotope technology, and in particular to a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] generator and separation method. Background Art

[0002] yttrium[ 90 Yttrium is a pure β-radioactive nuclide with a half-life of 64 hours. The maximum energy of the β-ray produced by decay can reach 2.28 MeV. 90 The decay daughters of 90 Zr is stable and non-toxic and will not affect the human body. In addition, yttrium[ 90 Y] has good chelating chemical properties and is easy to label monoclonal antibodies, microspheres, peptides, etc. for in vivo radiotherapy of cancer. 90 The radioactive microspheres containing yttrium [ 90 Y] can continuously irradiate the entire liver cancer cell, thereby causing cancer cell necrosis. And because the radiation radius of each microsphere is very small, it has almost no killing effect on the surrounding normal tissue. This precise radiotherapy method can kill cancer cells more effectively while causing less damage to normal tissue. Therefore, medical yttrium [ 90 The production of Y] nuclides is of great significance for the radiotherapy of liver cancer.

[0003] Medical Yttrium[ 90 The production methods of strontium [Y] are mainly reactors, nuclide generators, accelerators, etc. 90 Sr]-yttrium[ 90 Y] generator produces yttrium[ 90 Y] has the advantages of simple and fast operation and no regional restrictions on use, and the raw material strontium [ 90 Sr] is 235 The fission product of U can be obtained from spent fuel after long-term cooling and is currently the main source of yttrium production. 90 Y] is the main method. Strontium [ 90 Sr]-yttrium[ 90 The main preparation methods of yttrium generators include extraction, chromatography, precipitation, electrodeposition, liquid membrane, etc. However, these methods are complicated to operate, produce a large amount of radioactive waste liquid, etc., and the parent yttrium [ 90 Strontium [Y] is a highly toxic radionuclide of the bone-loving type with a half-life of 28.5 years. Its absorption in human bones is strictly restricted. 90 Sr]-yttrium[ 90 The separation requirements of strontium [ 90 Separation and purification of yttrium from Sr90 The mature technology of yttrium[ 90 The production and supply of strontium [Y] is completely dependent on imports. Therefore, the development of strontium [ 90 Sr]-yttrium[ 90 Y] generator is of great significance.

[0004] Currently, separation of strontium-containing 90 Sr] in the mother liquor 90 The generator of Y] mainly contains strontium [ 90 The recovery rate of Sr] is low, and the yttrium [ 90 Y] Strontium in the eluent 90 Sr]-yttrium[ 90 The radioactivity of Y] is high and the service life of the generator is short. Summary of the invention

[0005] In order to solve the above technical problems, the present invention provides a separation method containing strontium [ 90 Sr] in the mother liquor 90 Y] generator and separation method, the present invention comprises: 90 Sr] can be greatly avoided by adjusting the evaporation temperature of the eluent. 90 Sr] loss, and will not affect the yttrium [ 90 Y] separation effect.

[0006] To this end, the present invention provides the following technical solutions:

[0007] In a first aspect, the present invention provides, in an optional embodiment, a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, comprising the following steps:

[0008] S1: Strontium-containing 90 Sr] mother liquor passes through the resin separation column, and the yttrium in the mother liquor is 90 Y] is adsorbed, and the strontium [ 90 Sr] to elute and collect strontium [ 90 Sr] eluent, and then the liquid in the resin separation column is emptied with air;

[0009] S2: for strontium-containing 90 The eluent of Sr] is evaporated at 85-95°C to obtain strontium [ 90 Sr] crystals, dissolve the obtained crystals with eluent, and after 8-12 days, collect the corresponding eluent and add it to the strontium-containing [ 90 Sr] circulates in the mother liquor;

[0010] S3: Use the eluent to separate the yttrium on the resin column. 90 Y] to elute and collect yttrium-containing [ 90 Y] eluate;

[0011] Wherein, the yttrium-containing 90 Y] in the eluent, strontium [ 90 Sr]-yttrium[ 90 The radioactivity ratio of Y] is less than 10 -6 .

[0012] Containing strontium 90 Sr] eluent will cause strontium [ 90 Sr] loss, the present invention is to contain strontium [ 90 Sr] can be greatly avoided by adjusting the evaporation temperature of the eluent. 90 Sr] loss, and will not affect the yttrium [ 90 Y] separation effect.

[0013] Preferably, the method further comprises: 90 The eluate of Y] is then adsorbed by at least one set of resin separation columns, and the resin separation columns are eluted with the eluate to collect the purified yttrium-containing [ 90 Y] eluent. Furthermore, 90 The eluent of Y] is then adsorbed by a set of resin separation columns, and the resin separation columns are eluted with the eluent. The purified yttrium-containing [ 90 Y] in the eluent, strontium [ 90 Sr]-yttrium[ 90 The radioactivity ratio of Y] is less than 10 -7 . For yttrium-containing 90 The eluent of Y] is then adsorbed by two sets of resin separation columns, and the resin separation columns are eluted with the eluent. The purified yttrium-containing [ 90 Y] in the eluent, strontium [ 90 Sr]-yttrium[ 90 The radioactivity ratio of Y] is less than 10 -8 .

[0014] In the present invention, by 90 Y] eluate is purified several times to reduce the yttrium content [ 90 Y] in the eluate 90 Sr]-yttrium[ 90 Y] radioactivity.

[0015] Preferably, the total volume of the eluent used is at least 11 times the volume of the resin separation column; the elution rate is 0.25-1 mL / min; the concentration of the eluent is 1 mol / L, and the eluent is selected from one of nitric acid, sulfuric acid or hydrochloric acid; the concentration of the eluent is 8 mol / L, and the eluent is selected from one of nitric acid, sulfuric acid or hydrochloric acid.

[0016] In a second aspect, the present invention provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] generator, comprising a mother liquid tank, a rinsing tank, a first elution tank, a second elution tank, an automatic separation device and an evaporation recovery device, wherein the automatic separation device comprises a first separation column, a connecting device, a first injection pump and a second injection pump;

[0017] The connecting device is used to perform gated connection on the mother liquid tank, the elution tank, the first elution tank, the second elution tank, the first separation column, the first injection pump and the second injection pump;

[0018] The mother liquid tank is used to supply strontium-containing 90 Sr] mother liquor, and then using the first separation column to separate the strontium [ 90 Sr] in the mother liquor 90 Y] for adsorption;

[0019] The first injection pump is used to draw eluent from the eluent tank to elute the first separation column, and the strontium adsorbed on the first separation column is eluted. 90 Sr], is sent to the evaporation recovery device in the form of a solution;

[0020] The second injection pump is used to draw eluent from the first elution tank to elute the first separation column, and the eluted yttrium adsorbed on the first separation column 90 Y], sent to the second elution tank in the form of a solution;

[0021] The resin model of the first separation column is CL-P204 leaching resin, and the pore size is 80-150 mesh.

[0022] In the present invention, by selecting the CL-P204 leaching resin as the separation resin of the first separation column, the yttrium [ 90 Y] are all adsorbed in the resin, while strontium [ 90 Sr] flows out directly. 90 The extremely low chemical content of Sr[ 90 Sr] outflow directly and the resin material is exposed to less radiation, increasing the strontium [ 90Sr]-yttrium[ 90 Y] The service life of the generator.

[0023] Preferably, the evaporation recovery device comprises a liquid inlet pipe, an evaporating dish, a baffle, a liquid outlet and a heating device; the baffle is located inside the evaporating dish to prevent strontium [ 90 Sr] solution splashes during the evaporation process, and a small hole is opened on the baffle for the gas to be discharged after evaporation; the liquid inlet pipe is arranged on the baffle, and one end is connected to the connecting device and the elution tank, and the other end is suspended above the bottom of the evaporating dish; the liquid outlet is located on one side of the outer surface of the evaporating dish and is connected to the mother liquid tank; the heating device is located at the bottom of the evaporating dish, and is used to heat the strontium [ 90 Sr] solution is heated.

[0024] In the present invention, strontium [ 90 After the effluent of Sr] reaches the evaporation recovery device, it is concentrated and converted and then re-enters the automatic separation device for direct subsequent strontium [ 90 Sr] and yttrium [ 90 Y] separation, thereby ensuring that strontium [ 90 Sr] to extend the recovery rate of strontium [ 90 Sr]-yttrium[ 90 Y] The service life of the generator.

[0025] Preferably, the connecting device includes a first six-way valve, a second six-way valve and a third six-way valve; the common end C port of the first six-way valve is connected to the liquid inlet of the first separation column, the 1# port is connected to the 1# port of the second six-way valve, the 2# port is connected to the first elution tank through the second injection pump, the 3# port is connected to the 3# port of the second six-way valve, the 4# port is connected to the elution tank through the first injection pump, the 5# port is connected to the air, and the 6# port is connected to the 4# port of the second six-way valve; the 2# port of the second six-way valve is connected to the mother liquid tank, and the common end C port is connected to the liquid inlet of the first separation column; the common end C port of the third six-way valve is connected to the liquid outlet of the first separation column, the 1# port of the third six-way valve is connected to the liquid inlet pipe of the evaporation recovery device, and the 2# port of the third six-way valve is connected to the second elution tank.

[0026] In the present invention, the center holes of the first six-way valve, the second six-way valve and the third six-way valve are common channels, and the rotor can switch the multi-channel position to realize the alternating passage of different solutions, the flow channel diameter is 1.2mm, the port-to-port volume is 27.5μL, the rotor slot volume is 5.41μL, the liquid contact material is PCTEF or sapphire, the pipeline interface is a 1 / 4-28UNF threaded interface, the switching time is less than 4s / turn, and the maximum driving force is 4N / m. The design liquid volume accuracy error of the first syringe pump and the second syringe pump is less than 1%, and the liquid volume repeatability error is 0.3%-0.5%. According to the actual use, different specifications of sample injectors of 50μL to 10mL can be selected, the pipeline interface is a 1 / 4-28UNF threaded interface, and the rated stroke running time is 2s-12000s (pure water medium). The hardware that the control unit needs to control includes the first six-way valve, the second six-way valve, the third six-way valve, the first syringe pump and the second syringe pump, and the hardware used includes a 485 hub and a micro touch screen. The first six-way valve, the second six-way valve, the third six-way valve, the first injection pump and the second injection pump communicate through the 485 hub and the micro touch screen. The host computer software uses the computer serial port to send control commands to the 485 hub, and then the hub distributes the commands to each device, thereby realizing the control of the hardware device. The sealing material of the first separation column cover is thermoplastic polyurethane elastomer rubber, and the middle thread is polyetheretherketone material.

[0027] Preferably, the generator further comprises at least one set of separation columns for separating the yttrium eluted from the first separation column. 90 Y] solution is eluted again; the liquid inlet of each group of separation columns is connected to the first elution tank; the resin of at least one group of separation columns is CL-P204 leaching resin.

[0028] In the present invention, the yttrium adsorbed in the first separation column [ 90 Y] was eluted to obtain yttrium [ 90 Y] crude product, yttrium [ 90 Y] The eluate is then passed through at least one set of separation columns, and the selected CL-P204 leaching resin can adsorb yttrium [ 90 Y] in order to achieve the trace amount of impurities in yttrium [ 90 Y] crude product is purified again to increase the yttrium content of the product 90 Y] radiochemical purity. It can also improve the radiochemical purity of strontium [ 90 Sr] recovery rate, and will not affect the yttrium [ 90 Y] separation effect.

[0029] Preferably, the generator further comprises a control unit; the control unit is signal-connected to the connecting device, the first injection pump and the second injection pump; the liquid-contacting material of the connecting device is selected from one of polytrifluorochloroethylene and sapphire; the material of the evaporating dish is polyetheretherketone; and the liquid volume accuracy error of the first injection pump and the second injection pump is less than 1%.

[0030] In the present invention, a control unit is used to control the connecting device and each injection pump to achieve control of different liquid flow rates and flow directions, and remotely realize separation and recovery processes to ensure separation effects and reduce personnel exposure doses.

[0031] Compared with the prior art, the present invention has one of the following beneficial effects:

[0032] 1. The present invention can make yttrium [ 90 Y] are all adsorbed in the resin, while strontium [ 90 Sr] flows out directly. 90 The extremely low chemical content of Sr[ 90 Sr] outflow directly and the resin material is exposed to less radiation, increasing the strontium [ 90 Sr]-yttrium[ 90 Y] The service life of the generator.

[0033] 2. Strontium 90 After the effluent of Sr] reaches the evaporation recovery device, it is concentrated and converted and then re-enters the automatic separation device for direct subsequent strontium [ 90 Sr] and yttrium [ 90 Y] separation, thereby ensuring that strontium [ 90 Sr] to extend the recovery rate of strontium [ 90 Sr]-yttrium[ 90 Y] The service life of the generator.

[0034] 3. For the automatic separation device, a control unit is used to control the six-way valves and injection pumps to achieve control of the flow rate and direction of different liquids, and remotely realize the separation and recovery process to ensure the separation effect and reduce the exposure dose to personnel.

[0035] 4. The present invention is achieved by removing the yttrium adsorbed in the first separation column [ 90 Y] was eluted to obtain yttrium [ 90 Y] crude product, yttrium [ 90 The eluate then passes through a second separation column, where the selected leaching resin can adsorb yttrium [ 90 Y] in order to achieve the trace amount of impurities in yttrium [ 90 Y] crude product is purified again to increase the yttrium content of the product90 Y] radiochemical purity. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0037] Figure 1 This is a schematic diagram of a generator according to Embodiment 1 of the present invention;

[0038] Figure 2 This is a schematic diagram of a generator according to Embodiment 2 of the present invention;

[0039] Figure 3 This is a schematic diagram of a generator according to Embodiment 3 of the present invention;

[0040] Figure 4 This is a schematic diagram of the process of Example 4 of the present invention.

[0041] 1-mother liquid tank; 2-rinsing tank; 3-first elution tank; 4-second elution tank; 5-first six-way valve; 6-second six-way valve; 7-third six-way valve; 8-first separation column; 9-first injection pump; 10-second injection pump; 11-evaporating dish; 12-baffle; 13-small hole; 14-liquid inlet pipe; 15-liquid outlet; 16-heating device; 17-second separation column; 18-third separation column. DETAILED DESCRIPTION

[0042] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0043] The strontium content in the mother liquid tank 90 See Table 1 for the quality standards of the mother liquor:

[0044] Table 1 Quality Standards

[0045]

[0046]

[0047] Example 1

[0048] This embodiment provides a method for separating strontium-containing 90 Sr] in the mother liquor 90The generator of Y] comprises a mother liquid tank 1, a leaching tank 2, a first elution tank 3, a second elution tank 4, an automatic separation device, an evaporation recovery device and a control unit;

[0049] See also Figure 1 The automatic separation device includes a first separation column 8, a connecting device, a first injection pump 9 and a second injection pump 10. The connecting device includes a first six-way valve 5, a second six-way valve 6 and a third six-way valve 7. The resin of the first separation column 8 is CL-P204 leaching resin. The mother liquid tank 1 is used to supply strontium-containing liquid to the first separation column 8. 90 Sr] mother liquor, and then the first separation column 8 is used to separate the strontium-containing 90 Sr] in the mother liquor 90 Y] for adsorption, the first injection pump 9 is used to draw the eluent from the eluent tank 2 to elute the first separation column 8, and the strontium [ 90 Sr] is sent to the evaporation recovery device in the form of a solution. The second injection pump 10 is used to draw eluent from the first elution tank 3 to elute the first separation column 8. The yttrium [ 90 Y], is sent to the second elution tank 4 in the form of a solution.

[0050] The first six-way valve 5, the second six-way valve 6 and the third six-way valve 7 are used to select and connect the mother liquid tank 1, the washing tank 2, the first elution tank 3, the second elution tank 4, the first separation column 8, the first injection pump 9 and the second injection pump 10. Specifically, the common port C of the first six-way valve 5 is connected to the liquid inlet of the first separation column 8, the 1# port is connected to the 1# port of the second six-way valve 6, the 2# port is connected to the first elution tank 3 through the second injection pump 10, and the 3# port is connected to the 3# port of the second six-way valve 6. The first six-way valve 5, the second six-way valve 6, and the third six-way valve 7 are connected to the first separation column 8. The first six-way valve 5, the second six-way valve 6, and the third six-way valve 7 are connected to the first separation column 8. The first six-way valve 5, the second six-way valve 6, and the third six-way valve 7 are connected to the first separation column 8. The first six-way valve 5, the second six-way valve 6, and the third six-way valve 7 are connected to the first separation column 8. The first six-way valve 5, the second six-way valve 6, and the third six-way valve 7 are connected to the first separation column 8. The central holes are connected to the first six-way valve 5, the second six-way valve 6, and the third six-way valve 7. The central holes are common channels, and the rotor can switch the multi-channel positions to achieve the alternating passage of different solutions. The flow channel diameter is 1.2mm, the port-to-port volume is 27.5μL, the rotor slot volume is 5.41μL, the liquid contact material is PCTEF or sapphire, the pipeline interface is a 1 / 4-28UNF threaded interface, the switching time is less than 4s / turn, and the maximum driving force is 4N / m. The designed liquid volume accuracy error of the first injection pump and the second injection pump is less than 1%, and the liquid volume repeatability error is 0.3%-0.5%. Different specifications of sample injectors from 50μL to 10mL can be selected according to actual use conditions. The pipeline interface is a 1 / 4-28UNF threaded interface, and the rated stroke running time is 2s-12000s (pure water medium). The hardware that the control unit needs to control includes the first six-way valve 5, the second six-way valve 6, the third six-way valve 7, the first injection pump 9 and the second injection pump 10, and the hardware used includes a 485 hub and a micro touch screen. The first six-way valve 5, the second six-way valve 6, the third six-way valve 7, the first injection pump 9 and the second injection pump 10 communicate through the 485 hub and the micro touch screen. The upper computer software uses the serial port of the computer to send control commands to the 485 hub, and then the hub distributes the commands to each device, thereby realizing the control of the hardware device. The sealing material of the upper cover of the first separation column 8 is selected as thermoplastic polyurethane elastomer rubber, and the middle thread is selected as polyetheretherketone material.

[0051] The evaporation recovery device includes a liquid inlet pipe 14, an evaporation dish 11, a baffle 12, a liquid outlet 15 and a heating device 16; the baffle 12 is located inside the evaporation dish 11 to prevent strontium [ 90Sr] solution splashes during the evaporation process, and a small hole 13 is opened on the baffle 12 for discharging the evaporated gas; a liquid inlet pipe 14 is arranged on the baffle 12, and one end is connected to the connecting device and the elution tank 2, and the other end is suspended above the bottom of the evaporating dish 11; the liquid outlet 15 is located on one side of the outer surface of the evaporating dish 11 and is connected to the mother liquid tank 1; the heating device 16 is located at the bottom of the evaporating dish 11, and is used to heat the strontium [ 90 Sr] solution is heated.

[0052] The control unit is signal-connected to the first six-way valve 5 , the second six-way valve 6 , the third six-way valve 7 , the first injection pump 9 , and the second injection pump 10 .

[0053] Example 2

[0054] This embodiment provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] generator, comprising a mother liquid tank 1, a leaching tank 2, a first elution tank 3, a second elution tank 4, an automatic separation device, an evaporation recovery device, a second separation column 17 and a control unit;

[0055] See also Figure 1 The automatic separation device includes a first separation column 8, a connecting device, a first injection pump 9 and a second injection pump 10. The connecting device includes a first six-way valve 5, a second six-way valve 6 and a third six-way valve 7. The resin of the first separation column 8 is CL-P204 leaching resin. The mother liquid tank 1 is used to supply strontium-containing liquid to the first separation column 8. 90 Sr] mother liquor, and then the first separation column 8 is used to separate the strontium-containing 90 Sr] in the mother liquor 90 Y] for adsorption, the first injection pump 9 is used to draw the eluent from the eluent tank 2 to elute the first separation column 8, and the strontium [ 90 Sr] is sent to the evaporation recovery device in the form of a solution. The second injection pump 10 is used to draw eluent from the first elution tank 3 to elute the first separation column 8. The yttrium [ 90 Y], is sent to the second elution tank 4 in the form of a solution.

[0056] The first six-way valve 5, the second six-way valve 6 and the third six-way valve 7 are used to select and connect the mother liquid tank 1, the washing tank 2, the first elution tank 3, the second elution tank 4, the first separation column 8, the first injection pump 9 and the second injection pump 10. Specifically, the common port C of the first six-way valve 5 is connected to the liquid inlet of the first separation column 8, the 1# port is connected to the 1# port of the second six-way valve 6, the 2# port is connected to the first elution tank 3 through the second injection pump 10, and the 3# port is connected to the 3# port of the second six-way valve 6. The 4# port is connected to the elution tank 2 through the first injection pump 8, the 5# port is connected to the air, the 6# port is connected to the 4# port of the second six-way valve 6, the 2# port of the second six-way valve 6 is connected to the mother liquid tank 1, and the common port C is connected to the liquid inlet of the first separation column 8; the common port C of the third six-way valve 7 is connected to the liquid outlet of the first separation column 8, the 1# port of the third six-way valve 7 is connected to the liquid inlet pipe 14 of the evaporation recovery device, and the 2# port of the third six-way valve 7 is connected to the liquid inlet of the second separation column 17. The center holes of the first six-way valve 5, the second six-way valve 6 and the third six-way valve 7 are common channels, and the rotor can switch the multi-channel positions to realize the alternating passage of different solutions. The flow channel diameter is 1.2mm, the port-to-port volume is 27.5μL, the rotor slot volume is 5.41μL, the liquid contact material is PCTEF or sapphire, the pipeline interface is a 1 / 4-28UNF threaded interface, the switching time is less than 4s / turn, and the maximum driving force is 4N / m. The designed liquid volume accuracy error of the first injection pump and the second injection pump is less than 1%, and the liquid volume repeatability error is 0.3%-0.5%. Different specifications of sample injectors from 50μL to 10mL can be selected according to actual use conditions. The pipeline interface is a 1 / 4-28UNF threaded interface, and the rated stroke running time is 2s-12000s (pure water medium). The hardware that the control unit needs to control includes the first six-way valve 5, the second six-way valve 6, the third six-way valve 7, the first injection pump 9 and the second injection pump 10, and the hardware used includes a 485 hub and a micro touch screen. The first six-way valve 5, the second six-way valve 6, the third six-way valve 7, the first injection pump 9 and the second injection pump 10 communicate through the 485 hub and the micro touch screen. The upper computer software uses the serial port of the computer to send control commands to the 485 hub, and then the hub distributes the commands to each device, thereby realizing the control of the hardware device. The sealing material of the upper cover of the first separation column 8 is selected as thermoplastic polyurethane elastomer rubber, and the middle thread is selected as polyetheretherketone material.

[0057] The evaporation recovery device includes a liquid inlet pipe 14, an evaporation dish 11, a baffle 12, a liquid outlet 15 and a heating device 16; the baffle 12 is located inside the evaporation dish 11 to prevent strontium [ 90Sr] solution splashes during the evaporation process, and a small hole 13 is opened on the baffle 12 for discharging the evaporated gas; a liquid inlet pipe 14 is arranged on the baffle 12, and one end is connected to the connecting device and the elution tank 2, and the other end is suspended above the bottom of the evaporating dish 11; the liquid outlet 15 is located on one side of the outer surface of the evaporating dish 11 and is connected to the mother liquid tank 1; the heating device 16 is located at the bottom of the evaporating dish 11, and is used to heat the strontium [ 90 Sr] solution is heated.

[0058] The control unit is signal-connected to the first six-way valve 5 , the second six-way valve 6 , the third six-way valve 7 , the first injection pump 9 , and the second injection pump 10 .

[0059] The liquid inlet of the second separation column 17 is connected to the first elution tank 3 and the 2# port of the third six-way valve 5, and the liquid outlet is connected to the second elution tank 4. The resin of the second separation column 17 is CL-P204 leaching resin.

[0060] Example 3

[0061] This embodiment provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] generator, comprising a mother liquid tank 1, a rinsing tank 2, a first elution tank 3, a second elution tank 4, an automatic separation device, an evaporation recovery device, a second separation column 17, a third separation column 18 and a control unit;

[0062] See also Figure 1 The automatic separation device includes a first separation column 8, a connecting device, a first injection pump 9 and a second injection pump 10. The connecting device includes a first six-way valve 5, a second six-way valve 6 and a third six-way valve 7. The resin of the first separation column 8 is CL-P204 leaching resin. The mother liquid tank 1 is used to supply strontium-containing liquid to the first separation column 8. 90 Sr] mother liquor, and then the first separation column 8 is used to separate the strontium-containing 90 Sr] in the mother liquor 90 Y] for adsorption, the first injection pump 9 is used to draw the eluent from the eluent tank 2 to elute the first separation column 8, and the strontium [ 90 Sr] is sent to the evaporation recovery device in the form of a solution. The second injection pump 10 is used to draw eluent from the first elution tank 3 to elute the first separation column 8. The yttrium [ 90 Y], is sent to the second elution tank 4 in the form of a solution.

[0063] The first six-way valve 5, the second six-way valve 6 and the third six-way valve 7 are used to select and connect the mother liquid tank 1, the washing tank 2, the first elution tank 3, the second elution tank 4, the first separation column 8, the first injection pump 9 and the second injection pump 10. Specifically, the common port C of the first six-way valve 5 is connected to the liquid inlet of the first separation column 8, the 1# port is connected to the 1# port of the second six-way valve 6, the 2# port is connected to the first elution tank 3 through the second injection pump 10, and the 3# port is connected to the 3# port of the second six-way valve 6. The 4# port is connected to the elution tank 2 through the first injection pump 8, the 5# port is connected to the air, the 6# port is connected to the 4# port of the second six-way valve 6, the 2# port of the second six-way valve 6 is connected to the mother liquid tank 1, and the common port C is connected to the liquid inlet of the first separation column 8; the common port C of the third six-way valve 7 is connected to the liquid outlet of the first separation column 8, the 1# port of the third six-way valve 7 is connected to the liquid inlet pipe 14 of the evaporation recovery device, and the 2# port of the third six-way valve 7 is connected to the liquid inlet of the second separation column 17. The center holes of the first six-way valve 5, the second six-way valve 6 and the third six-way valve 7 are common channels, and the rotor can switch the multi-channel positions to realize the alternating passage of different solutions. The flow channel diameter is 1.2mm, the port-to-port volume is 27.5μL, the rotor slot volume is 5.41μL, the liquid contact material is PCTEF or sapphire, the pipeline interface is a 1 / 4-28UNF threaded interface, the switching time is less than 4s / turn, and the maximum driving force is 4N / m. The designed liquid volume accuracy error of the first injection pump and the second injection pump is less than 1%, and the liquid volume repeatability error is 0.3%-0.5%. Different specifications of sample injectors from 50μL to 10mL can be selected according to actual use conditions. The pipeline interface is a 1 / 4-28UNF threaded interface, and the rated stroke running time is 2s-12000s (pure water medium). The hardware that the control unit needs to control includes the first six-way valve 5, the second six-way valve 6, the third six-way valve 7, the first injection pump 9 and the second injection pump 10, and the hardware used includes a 485 hub and a micro touch screen. The first six-way valve 5, the second six-way valve 6, the third six-way valve 7, the first injection pump 9 and the second injection pump 10 communicate through the 485 hub and the micro touch screen. The upper computer software uses the serial port of the computer to send control commands to the 485 hub, and then the hub distributes the commands to each device, thereby realizing the control of the hardware device. The sealing material of the upper cover of the first separation column 8 is selected as thermoplastic polyurethane elastomer rubber, and the middle thread is selected as polyetheretherketone material.

[0064] The evaporation recovery device includes a liquid inlet pipe 14, an evaporation dish 11, a baffle 12, a liquid outlet 15 and a heating device 16; the baffle 12 is located inside the evaporation dish 11 to prevent strontium [ 90Sr] solution splashes during the evaporation process, and a small hole 13 is opened on the baffle 12 for discharging the evaporated gas; a liquid inlet pipe 14 is arranged on the baffle 12, and one end is connected to the connecting device and the elution tank 2, and the other end is suspended above the bottom of the evaporating dish 11; the liquid outlet 15 is located on one side of the outer surface of the evaporating dish 11 and is connected to the mother liquid tank 1; the heating device 16 is located at the bottom of the evaporating dish 11, and is used to heat the strontium [ 90 Sr] solution is heated.

[0065] The control unit is signal-connected to the first six-way valve 5 , the second six-way valve 6 , the third six-way valve 7 , the first injection pump 9 , and the second injection pump 10 .

[0066] The liquid inlet of the second separation column 17 is connected to the first elution tank 3 and the 2# port of the 36-way valve 6, and the liquid outlet is connected to the liquid inlet of the third separation column 18. The resin of the second separation column 17 is CL-P204 leaching resin.

[0067] The liquid inlet of the third separation column 18 is connected to the liquid outlet of the first elution tank 3 and the second separation column 17, and the liquid outlet is connected to the second elution tank 4. The resin of the third separation column 18 is CL-P204 leaching resin.

[0068] Example 4

[0069] This embodiment provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0070] The specific steps include:

[0071] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (CL-P204 leaching resin, pore size of 40-150 mesh, purchased from Zhengzhou Ainuo Chemical Technology Co., Ltd.) of the first separation column to balance the separation resin for 5 minutes.

[0072] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0073] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0074] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0075] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0076] Example 5

[0077] This embodiment provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 2, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0078] The specific steps include:

[0079] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (CL-P204 elution resin, pore size of 40-150 mesh) of the first separation column, and the separation resin is balanced for 5 minutes.

[0080] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0081] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0082] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0083] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second separation column through the common port C and port 2# of the third six-way valve.

[0084] S6: The product liquid eluted from the first separation column is passed through the separation resin (CL-P204 elution resin, pore size 40-150 mesh) in the second separation column at a rate of 1 mL / min, and a hydrochloric acid solution with a concentration of 8 mol / L is drawn from the first elution tank and passed through the separation resin in the second separation column, and the purified yttrium-containing [ 90 Y] eluent. The yttrium in the second elution tank [ 90 Y] solution is the collected yttrium-containing [90 Y] eluate.

[0085] Example 6

[0086] This embodiment provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 3, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0087] The specific steps include:

[0088] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and enters the separation resin (CL-P204 leaching resin) of the first separation column through the common port C of the first six-way valve to balance the separation resin for 5 minutes.

[0089] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0090] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0091] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0092] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second separation column through the common port C and port 2# of the third six-way valve.

[0093] S6: Make the product liquid eluted from the first separation column pass through the separation resin (CL-P204 leaching resin, pore size 40-150 mesh) in the second separation column at a rate of 1 mL / min, draw a hydrochloric acid solution with a concentration of 8 mol / L from the first elution tank, pass through the separation resin in the second separation column, and enter the third separation column.

[0094] S7: The product liquid eluted from the second separation column is passed through the separation resin (CL-P204 elution resin, pore size 40-150 mesh) in the third separation column at a rate of 1 mL / min, and a hydrochloric acid solution with a concentration of 8 mol / L is drawn from the first elution tank and passed through the separation resin in the third separation column, and the purified yttrium-containing [ 90 Y] eluent. The yttrium in the second elution tank [ 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0095] Example 7

[0096] This embodiment provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0097] The specific steps include:

[0098] S1: 2 mL of 1.5 mol / L nitric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (CL-P204 leaching resin, pore size of 40-150 mesh, purchased from Zhengzhou Ainuo Chemical Technology Co., Ltd.) of the first separation column, and the separation resin is balanced for 5 minutes.

[0099] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0100] S3: 11 mL of 1.5 mol / L nitric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0101] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1.5 mol / L nitric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0102] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3 mL of 6 mol / L nitric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0103] Comparative Example 1

[0104] This comparative example provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0105] The specific steps include:

[0106] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (cation exchange resin, pore size of 0.5-1.0 mm, purchased from Langfang Senate Chemical Co., Ltd., model SNT-D001) of the first separation column, and the separation resin is balanced for 5 minutes.

[0107] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0108] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0109] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0110] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0111] Comparative Example 2

[0112] This comparative example provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0113] The specific steps include:

[0114] S1: 2 mL of 1 mol / L hydrochloric acid solution was drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution was passed through the common port C of the first six-way valve into the separation resin (SR resin, pore size of 40-150 mesh, purchased from Zhejiang Zhengguang Industrial Co., Ltd., model SR-1) of the first separation column, and the separation resin was balanced for 5 minutes.

[0115] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0116] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0117] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0118] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0119] Comparative Example 3

[0120] This comparative example provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0121] The specific steps include:

[0122] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (HDEHP leaching resin, pore size of 40-120 mesh, purchased from Beijing Zhengguang Venture Technology Co., Ltd., model ZGCLP204) of the first separation column, and the separation resin is balanced for 5 min.

[0123] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0124] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0125] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0126] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0127] Comparative Example 4

[0128] This comparative example provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0129] The specific steps include:

[0130] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (strontium-specific crown ether resin, pore size of 40-120 mesh, produced by Triskem International, France, prepared by attaching 4,4'-(5')-di(tetra-butylcyclohexyl)-18-crown-6 to an inert monomer) of the first separation column, and the separation resin is balanced for 5 minutes.

[0131] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0132] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0133] S4: Strontium-containing 90The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0134] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0135] Comparative Example 5

[0136] This comparative example provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0137] The specific steps include:

[0138] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (CL-P204 elution resin, pore size of 40-150 mesh) of the first separation column, and the separation resin is balanced for 5 minutes.

[0139] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0140] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0141] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0142] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0143] Comparative Example 6

[0144] This comparative example provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0145] The specific steps include:

[0146] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (CL-P204 elution resin, pore size of 40-150 mesh) of the first separation column, and the separation resin is balanced for 5 minutes.

[0147] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0148] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0149] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0150] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0151] Comparative Example 7

[0152] This embodiment provides a method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, which is implemented using the generator of Example 1, but in the generator, the evaporation recovery device does not include a baffle, the volume of the resin separation column is 1 mL, and the 2-3 ml of the eluent is used as the product liquid.

[0153] The specific steps include:

[0154] S1: 2 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, and the solution is passed through the common port C of the first six-way valve into the separation resin (CL-P204 elution resin, pore size of 40-150 mesh) of the first separation column, and the separation resin is balanced for 5 minutes.

[0155] S2: Draw 2 mL of yttrium-containing liquid from the mother liquid tank at a rate of 0.5 mL / min from the 2# port of the second six-way valve. 90 Y] Sr[ 90 Sr] mother liquor, switch the second six-way valve to port 1#, switch the first six-way valve to port 1#, and make the yttrium-containing [ 90 Y] Sr[ 90 The mother liquor of yttrium [Sr] enters the first six-way valve through the 1# port of the second six-way valve, and enters the separation resin of the first separation column through the common port C of the first six-way valve at a rate of 1 mL / min, so that a large amount of yttrium [ 90 Y] and very small amounts of strontium [ 90 Sr] attached to the separation resin, the third six-way valve is switched to port 1, so that the strontium-containing 90 Sr] and very small amounts of yttrium [ 90 The Y] solution enters the third six-way valve through the common port C of the third six-way valve and from port 1#, and then enters the liquid inlet pipe of the evaporation recovery device.

[0156] S3: 11 mL of 1 mol / L hydrochloric acid solution is drawn from the elution tank through the first injection pump from the 4# port of the first six-way valve, the first six-way valve is switched to the 6# port, and the second six-way valve is switched to the 4# port, so that the eluent passes through the 6# port of the first six-way valve and enters the 4# port of the second six-way valve, and then enters the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1 mL / min, and the very small amount of strontium attached to the separation resin is removed. 90 Sr] for elution, the third six-way valve is switched to port 1#, so that the 90 The Sr] solution enters the liquid inlet pipe of the evaporation recovery device through the common port C and port 1# of the third six-way valve.

[0157] S4: Strontium-containing 90 The eluent of Sr] slowly enters the evaporating dish at a rate of 1 mL / min through the inlet pipe of the evaporation recovery device, evaporates at 90 ° C, and the evaporated gas is discharged through the small holes opened on the baffle. After the solution is completely evaporated, 1 mol / L hydrochloric acid solution drawn from the elution tank is added to dissolve all the solids. After standing for 10 days, [ 90 Sr]-yttrium[ 90 Y] eluent and add it to the mother liquid tank for recycling.

[0158] S5: Switch the port of the first six-way valve to the 5# port, use air to empty the liquid in the first separation column, then draw 3mL of 8mol / L hydrochloric acid solution from the second elution tank through the 2# port of the first six-way valve through the second injection pump, switch the first six-way valve to the 3# port, switch the second six-way valve to the 3# port, make the eluent pass through the 3# port of the first six-way valve, enter the 3# port of the second six-way valve, and make it enter the separation resin of the first separation column through the common port C of the second six-way valve at a rate of 1mL / min, so as to remove a large amount of yttrium attached to the separation resin. 90 Y] for elution, the third six-way valve is switched to port 2#, so that the yttrium containing a large amount of [ 90 The Y] solution enters the second elution tank through the common port C and port 2# of the third six-way valve. 90 Y] solution is the collected yttrium-containing [ 90 Y] eluate.

[0159] Experimental example

[0160] The strontium content in the eluent was detected by inductively coupled plasma emission spectrometry. According to the formula: Strontium recovery rate = 1-(Strontium in the eluent [ 90 Sr] content / strontium in strontium mother liquor [ 90 The strontium [Sr] content of Examples 4-7 and Comparative Examples 1-6 was calculated 90 The recovery rate of strontium [ 90 The detection results of Sr] and strontium [ 90 The recovery of Sr is shown in Table 2.

[0161] Table 2 Strontium [ 90 Sr] content and strontium [ 90 The recovery rate of Sr

[0162]

[0163]

[0164] Yttrium in the eluent was detected by inductively coupled plasma-atomic emission spectrometry. 90 The radiochemical activity of yttrium in the eluents of Examples 4-6 and Comparative Examples 1-6 is 90 The results of the radiochemical activity of Y] are shown in Table 3.

[0165] Table 3 Yttrium in the eluent [ 90 The radiochemical activity of Y

[0166]

[0167]

[0168] Conclusion: By comparing the data of Examples 4-6, it can be seen that by 90 Y] eluate is purified several times to reduce the yttrium content [ 90 Y] in the eluate 90 Sr]-yttrium[ 90 By comparing the data of Example 4 and Comparative Examples 1-4, it can be seen that the selection of CL-P204 leaching resin as the separation resin of the first separation column can make yttrium [ 90 Y] are all adsorbed in the resin, while strontium [ 90 Sr] flows directly out, through the yttrium [ 90 Y] can be eluted to reduce strontium [ 90 Sr]-yttrium[ 90 By comparing the data of Example 4 and Comparative Examples 5-6, it can be seen that when the evaporation temperature is higher than 95°C, it will cause strontium [ 90 The recovery rate of Sr] decreased due to the boiling phenomenon during evaporation. 90 Sr] will form aerosols along with the steam, causing strontium [ 90 Sr] loss, when the evaporation temperature is lower than 85℃, it will also cause strontium [ 90 The recovery rate of Sr] is reduced because the evaporation temperature is too low and the evaporated strontium [ 90 Sr] crystals will adhere to the surface of the evaporating dish, causing strontium [ 90 Sr] loss.

[0169] Although the principles of the present invention are described in detail above in conjunction with the preferred embodiments of the present invention, those skilled in the art should understand that the above embodiments are merely explanations of the exemplary implementations of the present invention, and are not intended to limit the scope of the present invention. The details in the embodiments do not constitute limitations on the scope of the present invention, and any obvious changes such as equivalent transformations, simple replacements, etc. based on the technical solution of the present invention, without departing from the spirit and scope of the present invention, fall within the protection scope of the present invention.

Claims

1. A method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, characterized in that The following steps are involved: S1: Strontium-containing 90 Sr] mother liquor passes through the resin separation column, and the yttrium in the mother liquor is 90 Y] is adsorbed, and the strontium [ 90 Sr] to elute and collect strontium [ 90 Sr] eluent, and then the liquid in the resin separation column is emptied with air; S2: for strontium-containing 90 The eluent of Sr] is evaporated at 85-95°C to obtain strontium [ 90 Sr] crystals, dissolve the obtained crystals with eluent, and after 8-12 days, collect the corresponding eluent and add it to the strontium-containing [ 90 Sr] circulates in the mother liquor; S3: Use the eluent to separate the yttrium on the resin column. 90 Y] to elute and collect yttrium-containing [ 90 Y] eluate; Wherein, the yttrium-containing 90 Y] in the eluent, strontium [ 90 Sr]-yttrium[ 90 The radioactivity ratio of Y] is less than 10 -6 .

2. The method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, characterized in that Also includes: For yttrium-containing 90 The eluate of Y] is then adsorbed by at least one set of resin separation columns, and the resin separation columns are eluted with the eluate to collect the purified yttrium-containing [ 90 Y] eluate.

3. The method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, characterized in that For yttrium-containing 90 The eluent of Y] is then adsorbed by a set of resin separation columns, and the resin separation columns are eluted with the eluent. The purified yttrium-containing [ 90 Y] in the eluent, strontium [ 90 Sr]-yttrium[ 90 The radioactivity ratio of Y] is less than 10 -7 .

4. The method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, characterized in that For yttrium-containing 90 The eluent of Y] is then adsorbed by two sets of resin separation columns, and the resin separation columns are eluted with the eluent. The purified yttrium-containing [ 90 Y] in the eluent, strontium [ 90 Sr]-yttrium[ 90 The radioactivity ratio of Y] is less than 10 -8 .

5. The method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] method, characterized in that The total volume of the eluent used is at least 11 times the volume of the resin separation column; The elution rate is 0.25-1 mL / min; The concentration of the eluent is 1 mol / L, and the eluent is selected from one of nitric acid, sulfuric acid or hydrochloric acid; The concentration of the eluent is 8 mol / L, and the eluent is selected from one of nitric acid, sulfuric acid or hydrochloric acid.

6. A method for separating strontium-containing 90 Sr] in the mother liquor 90 Y] generator, characterized in that It includes a mother liquid tank, a rinsing tank, a first elution tank, a second elution tank, an automatic separation device and an evaporation recovery device, wherein the automatic separation device includes a first separation column, a connecting device, a first injection pump and a second injection pump; The connecting device is used to perform gated connection on the mother liquid tank, the elution tank, the first elution tank, the second elution tank, the first separation column, the first injection pump and the second injection pump; The mother liquid tank is used to supply strontium-containing 90 Sr] mother liquor, and then using the first separation column to separate the strontium [ 90 Sr] in the mother liquor 90 Y] for adsorption; The first injection pump is used to draw eluent from the eluent tank to elute the first separation column, and the strontium adsorbed on the first separation column is eluted. 90 Sr], is sent to the evaporation recovery device in the form of a solution; The second injection pump is used to draw eluent from the first elution tank to elute the first separation column, and the eluted yttrium adsorbed on the first separation column 90 Y], sent to the second elution tank in the form of a solution; The resin model of the first separation column is CL-P204 leaching resin, and the pore size is 40-150 mesh.

7. The separation method according to claim 6 containing strontium 90 Sr] in the mother liquor 90 Y] generator, characterized in that The evaporation recovery device comprises a liquid inlet pipe, an evaporation dish, a baffle, a liquid outlet and a heating device; The baffle is located inside the evaporating dish to prevent strontium [ 90 Sr] solution splashes during the evaporation process, and the baffle is provided with small holes for the gas to be discharged after evaporation; The liquid inlet pipe is arranged through the baffle plate, and one end is connected to the connecting device and the elution tank, and the other end is suspended above the bottom of the evaporating dish; The liquid outlet is located on one side of the outer surface of the evaporating dish and is connected to the mother liquid tank; The heating device is located at the bottom of the evaporating dish and is used to heat the strontium in the evaporating dish. 90 Sr] solution is heated.

8. The separation method according to claim 1 containing strontium 90 Sr] in the mother liquor 90 Y] generator, characterized in that The communication device includes a first six-way valve, a second six-way valve and a third six-way valve; The common port C of the first six-way valve is connected to the liquid inlet of the first separation column, the 1# port is connected to the 1# port of the second six-way valve, the 2# port is connected to the first elution tank via the second injection pump, the 3# port is connected to the 3# port of the second six-way valve, the 4# port is connected to the elution tank via the first injection pump, the 5# port is connected to the air, and the 6# port is connected to the 4# port of the second six-way valve; The 2# port of the second six-way valve is connected to the mother liquid tank, and the common port C is connected to the liquid inlet of the first separation column; The common port C of the third six-way valve is connected to the liquid outlet of the first separation column, the 1# port of the third six-way valve is connected to the liquid inlet pipe of the evaporation recovery device, and the 2# port of the third six-way valve is connected to the second elution tank.

9. The separation method according to claim 1 containing strontium 90 Sr] in the mother liquor 90 Y] generator, characterized in that The generator also includes at least one set of separation columns for separating the yttrium eluted from the first separation column. 90 Y] solution is eluted again; the liquid inlet of each group of separation columns is connected to the first elution tank; The resin of at least one set of separation columns is CL-P204 leaching resin.

10. The separation method according to claim 1 90 Sr] in the mother liquor 90 Y] generator, characterized in that The generator also includes a control unit; The control unit is signal-connected with the communication device, the first injection pump and the second injection pump; The liquid contact material of the communication device is selected from one of polytrifluorochloroethylene and sapphire; The material of the evaporating dish is polyetheretherketone; The liquid volume accuracy error of the first injection pump and the second injection pump is less than 1%.

Images