Ultra-high dose rate radiation method and ultra-high dose rate radiation device

Abstract

The invention provides an ultrahigh dose rate radiation method, which comprises the following steps: controlling a plurality of beam modules to be positioned at a plurality of target positions in a one-to-one correspondence manner so as to form different radiation angles relative to the same target part; and under the condition that a to-be-radiated area of a target object is located at the target part, the beam modules are controlled to alternately emit multiple radiation beams to the target part from the different radiation angles, and each radiation beam in the multiple radiation beams has an ultrahigh dose rate. The invention further provides an ultrahigh dose rate radiation device.

Description

Technical Field

[0001] The present disclosure relates to the field of radiation inspection, in particular to the field of ultra-high dose rate radiation, and more particularly to an ultra-high dose rate radiation method and an ultra-high dose rate radiation device. Background Art

[0002] In the current ultra-high dose rate radiation implementation process, when the total radiation dose is too high, the same radiation source is often fixed and the dose is divided by multiple beam outputs; or in one time, a rotating head is used to output radiation at different rotation angles and divide the dose at multiple different angles. That is, when the total radiation dose is too high, radiation is carried out by time division and space division.

[0003] With the above-mentioned time division method, the same radiation source is required to emit beams multiple times, and the position or accelerator state needs to be readjusted before each time, which takes a long time and is cumbersome to operate. With the above-mentioned space division method, it is necessary to adjust the angle of the irradiation head (i.e., rotating head) at a faster speed during the conventional radiation beam emission process. In the field of rapid radiation, since the entire process is usually required to be completed in a shorter time, the irradiation head in conventional technology does not have time to rotate. Summary of the invention

[0004] In view of the above problems, the present disclosure provides an ultra-high dose rate radiation method and an ultra-high dose rate radiation device.

[0005] According to a first aspect of the present disclosure, there is provided an ultra-high dose rate radiation method, comprising: controlling a plurality of beam modules to be located at a plurality of target positions in a one-to-one correspondence so as to form different radiation angles relative to the same target portion; when an area to be irradiated of the target object is located at the target portion, controlling the plurality of beam modules to emit a plurality of radiation beams alternately from the different radiation angles to the target portion, wherein each of the plurality of radiation beams has an ultra-high dose rate.

[0006] In some embodiments, controlling the multiple beam modules to be located at multiple target positions one by one includes: determining multiple target angles of the multiple beam modules relative to the target portion according to the properties of the area to be irradiated; and controlling the beam module to move to the target position when there is no corresponding target angle between any beam module and the target portion.

[0007] In some embodiments, determining the multiple target angles of the multiple beam modules relative to the target portion based on the properties of the area to be irradiated includes: determining the multiple target angles of the multiple beam modules relative to the target portion based on the relative position relationship between the area to be irradiated and the surrounding non-target area, wherein the non-target area includes the area outside the area to be irradiated.

[0008] In some embodiments, determining the multiple target angles of the multiple beam modules relative to the target portion based on the relative position relationship between the area to be irradiated and the surrounding non-target areas includes: simulating each beam module sending a radiation beam to the area to be irradiated at different candidate angles based on the angles between each of the multiple beam modules, the radiation beam path of each beam module and the relative position relationship; and determining the multiple target angles based on the spatial interference relationship between the radiation beam simulated by each beam module at different candidate angles and the non-target areas.

[0009] In some embodiments, the plurality of target angles include at least one avoidance angle, and the radiation beam emitted by the beam module having the avoidance angle is configured to avoid the non-target area and hit the area to be irradiated.

[0010] In some embodiments, the multiple target angles include at least one protection angle, and the radiation beam emitted by the beam module with the protection angle is configured to pass through the non-target area and hit the area to be irradiated, and the radiation dose is less than the radiation dose of the radiation beam avoiding the non-target area.

[0011] In some embodiments, controlling the multiple beam modules to alternately emit multiple radiation beams to the target portion from the different radiation angles includes: detecting the current position of the area to be irradiated in real time; and controlling the multiple beam modules to alternately emit multiple radiation beams to the area to be irradiated at the different radiation angles during a time period when the current position of the area to be irradiated is located in the target portion.

[0012] In some embodiments, the multiple beam modules are distributed in a ring on a rotating assembly, and the target portion is located at the rotating axis of the rotating assembly, wherein controlling the multiple beam modules to be located at multiple target positions one-to-one includes: controlling the rotating assembly to rotate to drive the multiple beam modules to move to the multiple target positions one-to-one.

[0013] In some embodiments, the plurality of beam modules are distributed annularly in the rotating assembly, including: the position of any beam module is configured to avoid the radiation beam path of each of the other beam modules.

[0014] In some embodiments, the multiple beam modules emit multiple radiation beams alternately within a time less than or equal to 1 second; and / or, for any two adjacent beam modules sending radiation beams, the sending radiation beams are switched within a time less than or equal to 1 second.

[0015] Another aspect of an embodiment of the present disclosure provides an ultra-high dose rate radiation device, comprising: a rotating assembly; a plurality of beam modules for emitting multiple radiation beams, wherein the plurality of beam modules are distributed in a ring around the rotating assembly, and the rotating assembly drives the plurality of beam modules to move to a plurality of target positions corresponding to each other by rotation; and a control unit for executing a method as described in any one of the above items.

[0016] One or more of the above embodiments have the following beneficial effects: multiple beam modules are provided to send radiation beams from different angles to the target area to be irradiated, each radiation beam meets the ultra-high dose rate radiation requirement, and the radiation from different angles reduces the impact on the target object, completing the spatial division of the radiation dose. By switching and selecting different ray sources in an alternating beam output manner, the radiation requirement of switching angles in a very short time can be achieved, achieving the purpose of rapid radiation at multiple angles. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The above contents and other objects, features and advantages of the present disclosure will become more apparent through the following description of the embodiments of the present disclosure with reference to the accompanying drawings, in which:

[0018] Figure 1 A partial structural diagram of an ultra-high-dose radiation device according to an embodiment of the present disclosure is schematically shown;

[0019] Figure 2 A flowchart of an ultra-high dose rate radiation method according to an embodiment of the present disclosure is schematically shown;

[0020] Figure 3 A flowchart for controlling the movement of a beam module according to an embodiment of the present disclosure is schematically shown;

[0021] Figure 4 A partial structural diagram of a target object according to an embodiment of the present disclosure is schematically shown;

[0022] Figure 5 A flowchart for determining multiple target angles according to an embodiment of the present disclosure is schematically shown;

[0023] Figure 6 The flowchart of controlling the emitted radiation beam according to an embodiment of the present disclosure is schematically shown.

[0024] The reference numerals used in the above drawings include:

[0025] 100. Ultra-high dose rate radiation device; 110. Beam assembly; 111. First beam module; 112. Second beam module; 113. Third beam module; 114. Fourth beam module; 115. Fifth beam module; 140. Mounting support; 141. First support; 142. Second support; 120. Rotation assembly; 130. Target.

[0026] It should be noted that, for the sake of clarity, in the drawings used to describe the embodiments of the present disclosure, the sizes of the overall / local structures or the overall / local areas may be enlarged or reduced, that is, these drawings are not drawn according to the actual scale. DETAILED DESCRIPTION

[0027] Hereinafter, embodiments of the present disclosure will be described with reference to the accompanying drawings. However, it should be understood that these descriptions are exemplary only and are not intended to limit the scope of the present disclosure. In the following detailed description, for ease of explanation, many specific details are set forth to provide a comprehensive understanding of the embodiments of the present disclosure. However, it is apparent that one or more embodiments may also be implemented without these specific details. In addition, in the following description, descriptions of known structures and technologies are omitted to avoid unnecessary confusion of the concepts of the present disclosure.

[0028] Figure 1 The partial structural diagram of the ultra-high-dose radiation device 100 according to an embodiment of the present disclosure is schematically shown.

[0029] like Figure 1 As shown, the ultra-high dose radiation device 100 includes a beam assembly 110, a rotation assembly 120 and a mounting support 140. The beam assembly 110 may include a plurality of beam modules for emitting a plurality of radiation beams, for example, a first beam module 111, a second beam module 112, a third beam module 113, a fourth beam module 114 and a fifth beam module 115. The mounting support 140 may include a first support 141 and a second support 142. The first beam module 111, the second beam module 112 and the third beam module 113 may be mounted on the first support 141, and the fourth beam module 114 and the fifth beam module 115 may be mounted on the second support 142.

[0030] For example, the radiation device 100 involved in the present disclosure may include an ultra-high dose radiation device, which is used to generate a radiation beam that can be used in fields such as flash radiotherapy, container security inspection and industrial imaging, and can achieve ultra-high dose (for example, above 40Gy / s) radiation transfer, thereby completing the desired radiation in a very short time.

[0031] FLASH-RT (flash radiotherapy) involves the use of ultrafast delivery of radiation at dose rates that are several orders of magnitude higher than those used in conventional radiotherapy (e.g., 20-100 Gy / s compared to 1-4 Gy / min).

[0032] In some embodiments, the distances between the beam emission positions of the plurality of beam modules and the target portion 130 are substantially equal, which is beneficial to ensure that the radiation effects of the beam modules on the radiation area are substantially consistent, and is also beneficial to the accuracy of calibration.

[0033] Exemplarily, the rotating assembly 120 may include a roller, a circular ring (or a fixed ring of other shapes, such as a hexagonal, triangular, or irregularly shaped fixed ring, etc.). The rotating assembly 120 may rotate around its rotation axis, thereby driving the first beam module 111, the second beam module 112, the third beam module 113, the fourth beam module 114, and the fifth beam module 115 to rotate. For example, during the calibration process, the center of the target portion 130 is located at the rotation axis of the rotating assembly 120. Thus, during the rotation process, the rotating assembly 120 may rotate around the target portion 130. During the rotation process, by switching different beam modules to emit beams, the same target portion 130 (for example, a region to be irradiated) may be irradiated at different angles, wherein the radiation beam emitted by each beam module may achieve an ultra-high dose radiation effect. Multiple beam modules may emit beams in a sequential order and relative to a predetermined radiation region, or may emit beams in a disrupted order. Even when necessary, beams may be emitted simultaneously for radiation.

[0034] By setting a plurality of beam modules of different angles on a rotatable rotary assembly 120, the beam modules generating radiation are switched to achieve the purpose of rapidly irradiating at multiple angles in a very short time required in flash radiotherapy. That is, after calibration, the cooperation of the rotary assembly 120 and the plurality of beam modules can achieve ultra-high dose radiation at multiple angles to the predetermined radiation area.

[0035] For example, the beam module may include an electron linear accelerator. The radiation beam may include an X-ray beam. For example, the rotary assembly 120 has a receiving space therein, which may receive the target object to be irradiated. Figure 1 The target portion 130 is shown as a schematic location, which may be located within the rotating assembly 120. For example, a region of a target object to be irradiated may be located at the target portion 130 and irradiated by one or more radiation beams.

[0036] Understandably, Figure 1 The number, position and installation relationship of the middle beam modules are only examples and can be flexibly determined according to needs.

[0037] The following will be based on Figure 1 The described structure describes the ultra-high dose rate radiation method of the embodiment of the present disclosure in detail.

[0038] Figure 2 The flowchart of the ultra-high dose rate radiation method according to an embodiment of the present disclosure is schematically shown.

[0039] like Figure 2 As shown, this embodiment includes:

[0040] In operation S210, a plurality of beam modules are controlled to be located at a plurality of target positions in a one-to-one correspondence to form different radiation angles relative to a target portion;

[0041] Reference Figure 1 The plurality of beam modules may be at least two of the first beam module 111 , the second beam module 112 , the third beam module 113 , the fourth beam module 114 and the fifth beam module 115 .

[0042] The target object's area to be irradiated refers to a specific area that needs to be irradiated, such as an area of ​​interest of an object such as a workpiece or a container. The target is the area where the radiation beams of multiple beam modules converge. That is, the rays generated by multiple beam modules can pass through the same target as the radiation center to form the required radiation field that irradiates the same area. The target object may include a workpiece, a container, a vehicle, etc. to be inspected. The radiation angle includes the incident direction of the radiation beam relative to the target.

[0043] For example, multiple target positions of multiple beam modules can be manually confirmed, and instructions can be sent to a control unit (such as a computer, server or other electronic device) to perform operation S210. Alternatively, it can be automatically detected and controlled whether multiple beam modules are located at multiple target positions.

[0044] It can be understood that the target part is a determined area, and whether there is a target object to be irradiated in the target part can be detected manually or by sensors in real time, and then the target position of each beam module is determined. If the current position of each beam module is consistent with the target position, it remains unchanged. If the current position is inconsistent with the target position, it moves to the target position. For example, each beam module is detachable and can be moved to any position at will, or Figure 1 The rotational movement shown.

[0045] In operation S220, when the area to be irradiated of the target object is located at the target portion, a plurality of beam modules are controlled to alternately emit a plurality of radiation beams to the target portion from different radiation angles, wherein each of the plurality of radiation beams has an ultra-high dose rate.

[0046] The triggering sequence and working parameters of each electron gun in multiple beam modules are not restricted. Assuming there are 5 electron guns, they can be triggered in the order of 1-2-3-4-5, or in the order of 2-4-5, or in the order of 1-2-3-2, that is, they can be triggered in any combination, thereby maximizing the overall efficiency of the multi-electron gun system. High-speed data processing algorithms can be used to quickly decompose radiation task information, such as specific dose requirements under ultra-high dose radiation, into the dose (pulse dose) achieved by the single pulse signal of each electron gun, the number of pulses delivered, and the trigger timing.

[0047] like Figure 1The triggering order of each electron gun can be different under different radiation task requirements. The pulse control is realized by modular power supply and high-speed processor, that is, the parameters of the previous pulse signal and the electron gun port can be different from the parameters of the next pulse signal and the electron gun parameters, or the parameters of the previous pulse sequence and the electron gun port can be different from the parameters of the next pulse sequence and the electron gun parameters.

[0048] In some embodiments, a plurality of electron guns correspond one to one with a plurality of power supply ports, and controlling the power supply to alternately deliver matching pulse sequences to the plurality of electron guns in the plurality of radiation sources in sequence for power supply includes: controlling the power supply to alternately select the power supply ports corresponding to the electron guns (i.e., the electron gun ports mentioned above) in sequence, for example, switching the selected power supply ports within a time less than or equal to 1 second (e.g., within a time interval of 1 millisecond).

[0049] In some embodiments, multiple beam modules alternately emit multiple radiation beams within a time less than or equal to 1 second; and / or, for any two adjacent beam modules that send radiation beams, the radiation beams are switched within a time less than or equal to 1 second (such as a time interval of 1 millisecond).

[0050] According to the embodiments of the present disclosure, one power supply can power different electron guns, and the parameters of a single pulse signal are adjustable, that is, the pulse high voltage amplitude and pulse width are adjustable, and the power supply port output can also be specified to achieve fast and reliable switching in a complex electromagnetic environment.

[0051] For the electron gun in each beam module, N pulse signals can be transmitted to the target electron gun at intervals for power supply, including any two adjacent pulse signals being triggered at intervals, N is an integer greater than or equal to 2; wherein at least one of the N pulse signals is modulated according to at least one working parameter. Modulation includes adjusting the characteristics of the pulse signal, such as amplitude, frequency, etc., according to certain working parameters to adapt to different working conditions. After triggering M pulse signals, the superimposed dose of the radiation source to which the target electron gun belongs is obtained, wherein the superimposed dose includes the sum of the actual doses output by the radiation source measured in response to triggering the M pulse signals.

[0052] Exemplarily, the interval transmission pulse signal refers to triggering two adjacent pulse signals in the N pulse signals at a certain interval, such as a time interval between 0.1 microseconds and 1 millisecond, or 1 millisecond and hundreds of milliseconds. That is, the N pulse signals include a series of voltage peaks triggered at a certain interval, which are used to control the emission of the electron beam.

[0053] It can be understood that under different pulse signals, the electron gun has different electron emission capabilities. Two different pulse signals cause the electron gun to emit different electron beams. Due to many factors such as the service life of the electron gun, the single continuous beam emission time, the temperature change during the beam emission period, the manufacturing process, the material difference, and the different production batches after the replacement of spare parts, the performance of the electron emission of different electron guns is different, which is particularly obvious in the multi-electron gun system. Monitor the working state of the target electron gun in real time, and adjust the pulse parameters in time according to the dynamic changes of the gun state to maintain the overall working state stability. For example, the working parameters collected in real time by the first pulse signal and the second pulse signal in N pulse signals before triggering are different. Under the premise of outputting the same electron beam, the first pulse signal and the second pulse signal have different amplitudes and widths.

[0054] Exemplarily, each radiation beam in the plurality of radiation beams having an ultra-high dose rate may include a dose rate of each radiation beam being above 40 Gy / s.

[0055] Some technologies also have solutions for guiding the radiation beam into different angles by setting deflection irons at different angles in proton / heavy ion radiation. However, the use of deflection irons will bring additional dispersion (the effect can be reduced by de-dispersion through α iron, but it is not completely free of additional dispersion), and the deflection iron is large in size and complex to control. In addition, it is necessary to pay attention to other effects of the magnetic field on the beam during the design process, which is not convenient.

[0056] According to the embodiments of the present disclosure, multiple beam modules are provided to send radiation beams from different angles to irradiate the target, and each radiation beam meets the ultra-high dose rate radiation requirements. The radiation from different angles reduces the impact on the target object and completes the spatial division of the radiation dose. By switching and selecting different ray sources in an alternating beam output manner, the radiation requirements of switching the radiation angle can be met in a very short time, achieving the purpose of rapid radiation at multiple angles.

[0057] Figure 3 The flowchart for controlling the movement of the beam module according to an embodiment of the present disclosure is schematically shown.

[0058] like Figure 3 As shown, this embodiment is one of the embodiments of operation S210, including:

[0059] In operation S310, a plurality of target angles of a plurality of beam modules relative to a target portion are determined according to a property of the area to be irradiated;

[0060] In operation S320 , when any beam module does not have a corresponding target angle with the target portion, the beam module is controlled to move to a target position.

[0061] For example, this is achieved by physically adjusting the position of the beam module, using a robotic arm to move a beam module from an initial position to a position at a 45-degree angle above the patient's (target object) head (area to be irradiated).

[0062] Or, if Figure 1 , multiple beam modules are distributed in a ring on the rotating assembly, and the target part is located at the rotating axis of the rotating assembly, wherein controlling the multiple beam modules to be located at multiple target positions one by one includes: controlling the rotating assembly to rotate to drive the multiple beam modules to move to multiple target positions one by one.

[0063] Reference Figure 1 , based on a rotatable drum (i.e., a rotating assembly) for fixing beam modules, on which upper and lower beam module bases are fixed, and each beam module is fixed on the beam module base. The radiation beams output by all beam modules have a common intersection point, which overlaps with the center of the rotatable ring in space.

[0064] For example, the plurality of beam modules are first moved to a plurality of target positions by rotating the rotary assembly, and then the rotary assembly stops rotating, and the plurality of beam modules are allowed to emit beams alternately in a substantially stationary state.

[0065] It is understandable that the radiation angles required for the areas to be irradiated in most target objects are not completely unrelated. When a limited number of target angles are set, the radiation requirements can be met by rotating the entire rotary assembly and performing planned gating on the beam modules of these target angles.

[0066] Each time the rotating assembly is controlled to rotate, the multiple beam modules fixed on it will be re-positioned at several different fixed angles, which is equivalent to generating multiple new radiation angles in one rotation. At this time, the newly generated angles can be selected to select the appropriate spatial division scheme. The rotating assembly itself can rotate around a center, which is usually the same as the radiation center of the previous line, so that the radiation center does not need to be recalibrated after rotation. By switching different accelerator tubes to emit beams, the same area to be irradiated can be irradiated at different angles, and the radiation dose can be spatially divided. Multiple beam modules can emit beams in a sequential order or in a random order.

[0067] According to an embodiment of the present disclosure, a plurality of fixed-angle beam modules are arranged on a rotatable rotary assembly, and the beam modules for generating rays are switched to achieve the purpose of rapidly performing multiple-angle radiation in a very short time required in FLASH radiation.

[0068] In some embodiments, the plurality of beam modules are annularly distributed in the rotating assembly, including: the position of any beam module is configured to avoid the radiation beam path of each of the other beam modules.

[0069] Multiple beam modules try to avoid being in each other's beam paths, firstly to avoid damage to the beam modules by opposite rays, and secondly to obtain as many radiation angles as possible after rotation. For example, if the first beam module 111 and the fourth beam module 114 are in each other's beam paths, when the first beam module 111 rotates to the position of the fourth beam module 114, the fourth beam module 114 will also be exactly in the position of the first beam module 111. At this time, the two beam modules have only completed the position exchange after rotation, and no new angle distribution has been generated.

[0070] Figure 4 The schematic diagram shows a partial structure diagram of a target object according to an embodiment of the present disclosure. The area to be irradiated located in the left non-target area is filled with a pattern. The dotted arrow represents the radiation beam. In an optional application scenario, such as flash radiotherapy for a human body, the area to be irradiated may be a lesion area. Figure 4 The center-left non-target area may be the left lung, the right non-target area may be the right lung, and the center non-target area may be the heart.

[0071] In some embodiments, determining multiple target angles of multiple beam modules relative to the target according to the properties of the area to be irradiated includes: determining multiple target angles of multiple beam modules relative to the target according to the relative position relationship between the area to be irradiated and the surrounding non-target area. This can reduce damage to surrounding tissues and reduce side effects of radiation.

[0072] It can be understood that the non-target area refers to the area outside the area to be irradiated. Figure 1 , the target object enters the interior of the rotating assembly so that its specific area to be irradiated can be adjusted to the target. Then, based on the relative position relationship between the current area to be irradiated and the surrounding non-target area, multiple target angles of multiple beam modules relative to the target are calculated.

[0073] For example, refer to Figure 4 , detailed images of non-target areas can be obtained through CT scanning, the position of the area to be irradiated and its relative position relationship with other non-target areas can be determined, and the best radiation angle can be calculated.

[0074] For example, the target angle of each beam module can be calculated based on geometric optimization, such as inputting the three-dimensional coordinate data of the area to be irradiated and the surrounding non-target area (obtained using imaging equipment), and then constructing the area to be irradiated and the key non-target area into a three-dimensional model to facilitate the analysis of spatial relationships. Define a risk function that comprehensively considers the radiation dose distribution and the sensitivity of the surrounding non-target area. The goal is to find a set of angles that minimizes radiation to the surrounding non-target area while ensuring that the area to be irradiated receives a sufficient dose. Genetic algorithms, particle swarm optimization (PSO) or other global optimization algorithms can be used to find the set of angles that minimize the risk function. Then output the optimal target angle of each beam module relative to the target.

[0075] Alternatively, target angle calculation is performed based on machine learning algorithms, and historical target object radiation data is collected and annotated, including the location information of the area to be irradiated and the surrounding non-target areas, as well as the corresponding optimal beam angle. Key features in the historical target object radiation data are extracted, such as the center coordinates of the area to be irradiated, the minimum distance to the surrounding non-target areas, etc. Training models such as random forest algorithms and neural network algorithms are used to learn the relationship between features and optimal angles. For new target objects, their feature data (such as appearance, internal structure, etc.) is input, and the model predicts the optimal set of target angles.

[0076] Alternatively, use the following Figure 5 The target angle is calculated by

[0077] Figure 5 The flowchart of determining multiple target angles according to an embodiment of the present disclosure is schematically shown.

[0078] like Figure 5 As shown, in this embodiment, according to the relative position relationship between the area to be irradiated and the surrounding non-target area, determining multiple target angles of multiple beam modules relative to the target portion includes:

[0079] In operation S510, according to the angles between two of the plurality of beam modules, the radiation beam path of each beam module, and the relative position relationship, each beam module is simulated to send a radiation beam to the to-be-irradiated area at different candidate angles;

[0080] In operation S520, multiple target angles are determined according to the spatial interference relationship between the radiation beam simulated by each beam module at different candidate angles and the surrounding non-target area. The spatial interference relationship includes whether the radiation beam passes through the surrounding non-target area.

[0081] For example, the three-dimensional coordinate data of multiple beam modules, the lesion area and the surrounding organs are obtained through imaging equipment, so as to obtain the angles between the multiple beam modules, the radiation beam path of each beam module and the relative position relationship. Use simulation software (such as Monte Carlo or medical three-dimensional simulation software) to set the simulation parameters, including the radiation beam path and dose of the beam module. Simulate the path of the radiation beam through the patient's body and calculate the dose distribution of the lesion area and surrounding organs. Adjust the angles of each beam module and repeat the simulation process until the optimal angle set is found. Optionally, these angles can then be displayed to the operator through the software interface, and the operator or the automated system can be guided to adjust the beam modules.

[0082] According to the embodiments of the present disclosure, by finding the preferred angle in advance by simulating the beam output, unnecessary damage to non-target areas during actual radiation can be avoided.

[0083] In some embodiments, the plurality of target angles include at least one avoidance angle, and the radiation beam emitted by the beam module having the avoidance angle is configured to avoid surrounding non-target areas and hit the area to be irradiated.

[0084] In some embodiments, the multiple target angles include at least one protection angle, and the radiation beam emitted by the beam module with the protection angle is configured to pass through the surrounding non-target area to hit the area to be irradiated, and the radiation dose is less than the radiation dose of the radiation beam that avoids the surrounding non-target area.

[0085] For example, if the total dose requirement is 100 cGy, the five target doses allocated to the five beam modules may be 30 cGy, 20 cGy, 10 cGy, 15 cGy, and 25 cGy. If there is a situation where the surrounding non-target areas cannot be avoided, the radiation dose is reduced accordingly, for example, 10 cGy. However, it has a smaller dose than the radiation beam that avoids the non-target area (such as a beam with a dose of 30 cGy).

[0086] According to the embodiments of the present disclosure, by adjusting the target angles of each beam module, the desired area on the target object can be accurately irradiated, and non-target areas can be effectively avoided or the radiation dose can be reduced, thereby avoiding adverse effects on the target object.

[0087] Figure 6 The flowchart of controlling the emitted radiation beam according to an embodiment of the present disclosure is schematically shown.

[0088] The position of the area to be irradiated may change dynamically, for example, the lesions in the human body may change dynamically with the patient's physiological movements (such as breathing, talking, etc.). Figure 6 As shown, this embodiment is one of the embodiments of operation S220, including:

[0089] In operation S610, the current position of the area to be irradiated is detected in real time; for example, a real-time imaging technology is used to monitor the change in the position of the area to be irradiated of the container.

[0090] In operation S620, when the current position of the area to be irradiated is located at the target part, multiple beam modules are controlled to alternately emit multiple radiation beams to the area to be irradiated at different radiation angles. For example, during the patient's breathing cycle, the lesion area stays at the target part for 0.3 seconds, and then the alternating beams are completed within 0.3 seconds.

[0091] According to the embodiments of the present disclosure, each radiation beam can be accurately directed to the dynamically changing position of the area to be irradiated through real-time detection.

[0092] It will be appreciated by those skilled in the art that the features described in the various embodiments of the present disclosure may be combined and / or combined in a variety of ways, even if such combinations or combinations are not explicitly described in the present disclosure. In particular, without departing from the spirit and teachings of the present disclosure, the features described in the various embodiments of the present disclosure may be combined and / or combined in a variety of ways. All of these combinations and / or combinations fall within the scope of the present disclosure.

[0093] The embodiments of the present disclosure are described above. However, these embodiments are only for illustrative purposes and are not intended to limit the scope of the present disclosure. Although the embodiments are described above separately, this does not mean that the measures in the various embodiments cannot be used in combination to advantage. The scope of the present disclosure is defined by the attached claims and their equivalents. Without departing from the scope of the present disclosure, those skilled in the art may make a variety of substitutions and modifications, which should all fall within the scope of the present disclosure.

Claims

1. An ultra-high dose rate radiation method, comprising: Controlling a plurality of beam modules to be located at a plurality of target positions in a one-to-one correspondence, so as to form different radiation angles relative to the same target portion; When the area to be irradiated of the target object is located at the target portion, the multiple beam modules are controlled to alternately emit multiple radiation beams to the target portion from the different radiation angles, wherein each of the multiple radiation beams has an ultra-high dose rate.

2. The method according to claim 1, characterized in that The controlling of the plurality of beam modules to be located at a plurality of target positions in a one-to-one correspondence includes: Determining a plurality of target angles of the plurality of beam modules relative to the target portion according to the properties of the area to be irradiated; When there is no corresponding target angle between any beam module and the target portion, the beam module is controlled to move to the target position.

3. The method according to claim 2, characterized in that The step of determining the multiple target angles of the multiple beam modules relative to the target portion according to the properties of the area to be irradiated comprises: A plurality of target angles of the plurality of beam modules relative to the target portion are determined according to a relative positional relationship between the region to be irradiated and surrounding non-target regions, wherein the non-target regions include regions outside the region to be irradiated.

4. The method according to claim 3, characterized in that Determining a plurality of target angles of the plurality of beam modules relative to the target portion according to the relative position relationship between the area to be irradiated and the surrounding non-target area comprises: According to the angles between the multiple beam modules, the radiation beam path of each beam module and the relative position relationship, simulating each beam module to send a radiation beam to the area to be irradiated at different candidate angles; The multiple target angles are determined according to the spatial interference relationship between the radiation beam simulated by each beam module at different candidate angles and the non-target area.

5. The method according to claim 4, characterized in that The multiple target angles include at least one avoidance angle, and the radiation beam emitted by the beam module having the avoidance angle is configured to avoid the non-target area and hit the area to be irradiated.

6. The method according to claim 4 or 5, characterized in that: The multiple target angles include at least one protection angle, and the radiation beam emitted by the beam module with the protection angle is configured to pass through the non-target area and hit the area to be irradiated, and the radiation dose is less than the radiation dose of the radiation beam avoiding the non-target area.

7. The method according to claim 3, characterized in that The controlling the plurality of beam modules to alternately emit a plurality of radiation beams to the target portion from the different radiation angles comprises: Detecting the current position of the area to be irradiated in real time; During a time period when the current position of the area to be irradiated is located at the target portion, the plurality of beam modules are controlled to alternately emit a plurality of radiation beams to the area to be irradiated at the different radiation angles.

8. The method according to any one of claims 1 to 5 and 7, characterized in that: The multiple beam modules are distributed in an annular manner on the rotating assembly, and the target portion is located on the rotating axis of the rotating assembly. The controlling of the plurality of beam modules to be located at a plurality of target positions in a one-to-one correspondence includes: The rotary assembly is controlled to rotate to drive the plurality of beam modules to move to the plurality of target positions corresponding to each other.

9. The method according to claim 8, characterized in that The plurality of beam modules are distributed in an annular manner in the rotating assembly and include: The position of any one beam module is configured to avoid the radiation beam path of each of the other beam modules.

10. The method according to any one of claims 1 to 5, 7 or 9, characterized in that: In a time less than or equal to 1 second, the plurality of beam modules emit a plurality of radiation beams alternately; and / or, For any two adjacent beam modules that transmit radiation beams, the transmitted radiation beams are switched within a time less than or equal to 1 second.

11. An ultra-high dose rate radiation device, comprising: Rotary components; A plurality of beam modules for emitting a plurality of radiation beams, wherein the plurality of beam modules are distributed in an annular manner around the rotating assembly, and the rotating assembly drives the plurality of beam modules to move to a plurality of target positions corresponding to each other by rotating; A control unit, configured to execute the method according to any one of claims 1 to 10.

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