Disintegration time limit end point automatic sensing system, method and device
By designing the automatic sensing device for the end point of the disintegration time limit, the photoelectric sensor and motion state sensor are used to realize automatic timing of the end point of the drug disintegration time limit, solving the problems of high R&D cost and large measurement error of the automatic detection device in the prior art, and realizing a low-cost and high-reliability automatic sensing system.
Patent Information
- Application Number
- CN202510281870.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-11
- Publication Date
- 2025-06-03
- Estimated Expiration
- 2045-03-11
AI Technical Summary
In the prior art, the automatic detection device with disintegration time limit end points has problems such as high R&D cost and large measurement errors, and the control principle is complex, making it difficult to realize a low-cost and high-reliability automatic sensing system.
An automatic sensing device for endpoint of disintegration time is designed, including a disintegrator body, a photoelectric sensor and a motion state sensor. The disintegration of the drug is detected through the photoelectric sensor, and the lifting and lowering motion of the hanging basket is controlled by using the motion state sensor to realize automatic timing of the endpoint of the disintegration time.
It realizes automatic timing of the end point of the disintegration time limit of the drug to be tested, saves manpower, reduces manufacturing costs, has simple control principles, and is highly reliable.
Smart Images

Figure CN120084959A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of automatic disintegration time limit sensing, and particularly relates to an automatic disintegration time limit end sensing system, method and device. Background Art
[0002] Disintegration means that a solid preparation completely disintegrates, dissolves or becomes fragmented within the inspection time limit. Except for insoluble coating materials or broken capsule shells, it should pass through a sieve. The disintegration time limit is measured using a lifting disintegrator. Ordinary tablets should completely disintegrate within 15 minutes, hard capsules in capsule preparations should completely disintegrate within 30 minutes, and soft capsules should completely disintegrate within one hour. The confirmation of the disintegration time limit generally uses visual observation, which has subjective errors and consumes manual working hours.
[0003] In the prior art, for an automatic detection device for the disintegration end point, such as a device for accurately judging the disintegration time limit end point of a preparation disclosed in the Chinese utility model patent with the publication number CN215493284U, its principle is to judge whether the drug is dissolved by the pressure between the drug and the sieve during the upward movement process, and its main technical feature is the induction sieve. This technical solution has the following problems in the practical process: on the one hand, the induction sieve applicable to the disintegrator is not a standard induction device, and no specific manufacturer is investing in manufacturing. Therefore, during the R & D process, it is necessary to design the induction device from scratch, and the R & D cost is high; on the other hand, the solution above the sieve will generate a certain pressure on the sieve during the upward movement. Since the drug in the to-be-disintegrated state is relatively light in itself, it will cause a large measurement error. Summary of the Invention
[0004] To overcome the deficiencies of the above prior art, the present invention provides an automatic disintegration time limit end sensing device, which can realize automatic timing of the disintegration time limit end point of the drug to be tested, save manpower, and has the advantages of low manufacturing cost, simple control principle and good reliability compared with the prior art technical solutions for automatic detection devices for the disintegration end point.
[0005] To achieve the above object, the present invention is realized by the following technical solutions: An automatic disintegration time limit end sensing device includes: A disintegrator main body, which includes a hanging basket and a lifting drive device for driving the hanging basket to reciprocate up and down; A tube body installed on the hanging basket, and a conical mesh cover is provided at the bottom of the tube body, and the diameter of the upper end of the conical mesh cover is larger than that of the lower end; An optoelectronic sensor, which includes a transmitter and a receiver. The transmitter is installed below the conical mesh cover and its emission port is directly opposite to the bottom opening of the conical mesh cover. When the drug sinks to the bottom end of the conical mesh cover before complete disintegration, it can block the optical signal emitted by the transmitter. The receiver is arranged above the conical mesh cover and its receiving port is directly opposite to the emission port of the transmitter; A motion state sensor for detecting whether the motion state of the hanging basket is in a preset ascending stroke.
[0006] Optionally, in a disintegration time limit end automatic induction device in the present application, the lifting drive device includes a rotary transmission member and a linear movement component. The rotary transmission member is in transmission connection with the linear movement component, and the linear movement component is connected to the hanging basket. An induction magnetic block is provided on the rotary transmission member; the motion state sensor includes a Hall sensor, and the Hall sensor is arranged on one side of the induction magnetic block. When the rotary transmission member drives the induction magnetic block to rotate to a position corresponding to the Hall sensor, at this time, the linear movement component drives the hanging basket to be in the preset ascending stroke.
[0007] Optionally, in a disintegration time limit end automatic induction device in the present application, the motion state sensor includes an acceleration sensor. When the acceleration sensor receives a signal of upward accelerated motion, it is determined that the hanging basket is in the preset ascending stroke.
[0008] Furthermore, in a disintegration time limit end automatic induction device in the present application, it further includes a transmitter mounting bracket. The transmitter mounting bracket is installed at the lower end of the tube body and is connected to the tube body. The transmitter mounting bracket includes a base, and an installation counterbore is provided at the bottom of the base. The transmitting end of the transmitter is arranged in the installation counterbore, and a light-transmitting perforation is provided through the top of the installation counterbore, and the light-transmitting perforation corresponds to the transmitting port of the transmitter.
[0009] Furthermore, in a disintegration time limit end automatic induction device in the present application, the hanging basket includes an upper limit disk and a lower limit disk. The upper limit disk is arranged at the upper end of a group of tube bodies, and a group of tube bodies are inserted through the lower limit disk. Limit holes adapted to the tube bodies are provided on the upper limit disk and the lower limit disk; It further includes a connecting rod. The connecting rod penetrates through the upper limit disk and the lower limit disk. A group of positioning nuts are sleeved on the outer wall of the connecting rod. The positioning nuts realize the axial positioning of the upper limit disk and the lower limit disk relative to the connecting rod, and the upper end of the connecting rod is connected to the lifting drive device.
[0010] Furthermore, in a disintegration time limit end automatic induction device in the present application, the connecting rod is a hollow tube body with openings at both ends, and the lower end of the connecting rod extends to correspond to the transmitter.
[0011] A disintegration time limit end automatic induction system includes: A lifting drive module for controlling the lifting drive device to drive the hanging basket to reciprocate up and down; A motion state induction module for detecting that the hanging basket is in a preset ascending stroke to activate the photoelectric sensor; A disintegration completion confirmation module for detecting whether the drug has completed disintegration after the photoelectric sensor is activated; A timing module for measuring the time from the start to the completion of disintegration.
[0012] An automatic induction method for the disintegration time limit end point, based on an automatic induction device for the disintegration time limit end point, includes the following steps: Load the drug into the tube body of the hanging basket and place it between the conical mesh cover and the receiver; Immerse the tube body in the solution and drive the hanging basket to reciprocate up and down through the lifting drive device; The photoelectric sensor is activated when the detected motion state of the hanging basket is in the preset upward stroke; When the receiver receives the optical signal emitted by the transmitter, it is determined that the drug has completed disintegration.
[0013] From the above technical solutions, it can be seen that the present invention has the following beneficial effects: This application provides an automatic induction device for the disintegration time limit end point. Its principle is: The drug placed in the tube body sinks to the bottom of the tube body. Due to the setting of the conical screen cover, the drug will automatically be centered in the conical screen cover due to gravity. At this time, it just blocks the emission port of the transmitter. During the disintegration experiment, when the hanging basket moves upward, the drug will fit with the conical screen cover. At this time, it can be ensured that the undisintegrated drug blocks the emission port of the transmitter, so that the receiver cannot detect the optical signal emitted by the transmitter; When the drug has completed disintegration, at this time, there is no blockage between the transmitter and the receiver, and at this time the receiver can receive the optical signal, thereby triggering the stop timing, outputting the timing data, and obtaining the disintegration time limit end point time. Therefore, the automatic induction device for the disintegration time limit end point described in the present invention can realize the automatic timing of the disintegration time limit end point of the drug to be tested, saving manpower. Compared with the existing technical solutions for the automatic detection device of the disintegration end point, it has the advantages of low manufacturing cost, simple control principle, and good reliability. Description of the Drawings
[0014] Figure 1 It is a three-dimensional structure diagram of an automatic induction device for the disintegration time limit end point in an embodiment of this application; Figure 2 It is a structure diagram of the lifting drive device; Figure 3 It is an installation diagram of a Hall sensor and an induction magnet block in an automatic induction device for the disintegration time limit end point in an embodiment of this application; Figure 4 It is a three-dimensional structure diagram of the hanging basket; Figure 5 It is an exploded view of the components of the hanging basket; Figure 6 It is a cross-sectional view of the hanging basket; Figure 7 It is Figure 6 A partial enlarged view of the area circled A in
[0015] In the figure: 1 - Disintegrator main body; 11 - Water bath tank; 12 - Lifting drive device; 121 - Rotary transmission member; 122 - Linear movement assembly; 123 - Inductive magnet block; 124 - Lifting rod; 125 - Extension plate; 126 - Suspension rod; 13 - Hall sensor; 2 - Basket; 21 - Tube body; 22 - Conical screen cover; 221 - Conical bottom; 222 - Ring sleeve; 23 - Upper limit disk; 24 - Lower limit disk; 25 - Connecting rod; 251 - Positioning nut; 252 - Wire groove; 253 - Limit cap; 254 - Mounting plate; 255 - Wire perforation; 26 - Support plate; 3 - Beaker; 4 - Photoelectric sensor; 41 - Transmitter; 42 - Receiver; 421 - Floating head; 422 - Notch; 5 - Transmitter mounting bracket; 51 - Base; 511 - Mounting counterbore; 512 - Light - transmitting perforation; 513 - Conical mating surface; 5134 - Limit platform; 52 - Collar; 53 - Connecting plate. Detailed implementation mode Embodiment
[0016] Combined with Figures 1 to 5 An automatic induction device for the end point of disintegration time limit shown in the figure, including a disintegrator main body 1. The disintegrator main body 1 includes a water bath tank 11 and a lifting drive device 12, and also includes a beaker 3 and a basket 2. The beaker 3 is arranged in the water bath tank 11, and the basket 2 is arranged in the beaker 3. The lifting drive device 12 can drive the basket 2 to reciprocate up and down in the beaker 3. A group of tube bodies 21 are arranged in the basket 2. A conical screen cover 22 is arranged at the bottom of the tube body 21. The upper and lower ends of the conical screen cover 22 are open, and the diameter of the upper end of the conical screen cover 22 is larger than that of the lower end. It also includes a photoelectric sensor 4. The photoelectric sensor 4 includes a transmitter 41 and a receiver 42. The transmitter 41 is arranged below the conical screen cover 22, and the emission port of the transmitter 41 corresponds to the central position of the conical screen cover 22. The receiver 42 is arranged above the conical screen cover 22, and the receiving port of the receiver 42 corresponds to the emission port of the transmitter 41. The transmitter 41 and the receiver 42 are electrically connected to the disintegrator control system; A motion state sensor is used to detect whether the motion state of the basket 2 is in a preset upward stroke.
[0017] In this embodiment, the lifting drive device 12 includes a rotary transmission member 121 and a linear movement assembly 122. The rotary transmission member 121 is in transmission connection with the linear movement assembly 122. The linear movement assembly 122 is connected to the hanging basket 2. An induction magnetic block 123 is provided on the rotary transmission member 121. Correspondingly, the motion state sensor includes a Hall sensor 13. The Hall sensor 13 is arranged on one side of the induction magnetic block 123. The Hall sensor 13 is electrically connected to the disintegration tester control system. When the rotary transmission member 121 drives the induction magnetic block 123 to rotate to a position corresponding to the Hall sensor 13, at this time, the linear movement assembly 122 is in an upward movement stroke.
[0018] Specifically, the conical screen cover 22 is integrally in the shape of a trumpet-shaped cover cylinder. In this embodiment, the number of the tube bodies 21 is 6, and they are arranged at equal intervals circumferentially.
[0019] A method for using an automatic induction device for the end point of the disintegration time limit of this embodiment includes the following steps: S1: Preparation. A solution is placed in the water bath tank 11 and the beaker 3. The hanging basket 2 is immersed in the beaker 3. The lifting drive device 12 is connected to the hanging basket 2. S2: Start. The pill to be tested is placed into the tube body 21. The disintegration tester is started. The lifting drive device 12 drives the hanging basket 2 to move up and down in the beaker 3. The counting module of the disintegration tester control system starts timing at the same time. In order to prevent the drug from moving up and down for too long, a limit cover (not shown) that can sink into the solution in the medicine immersion cavity can be set to cover the drug. The limit cover is provided with a through hole whose position is directly opposite to the transmitter 41. The size of the through hole is the same as the mesh hole of the conical screen cover 22.
[0020] S3: Transmit optical signal. When the hanging basket 2 moves upward, the induction magnetic block 123 rotates to a position corresponding to the Hall sensor 13. At this time, the Hall sensor 13 outputs a signal to the controller, and the controller controls the transmitter 41 to transmit an optical signal. S4: End point timing. After the pill is completely disintegrated, there is no blocking object between the receiver 42 and the transmitter 41. When the receiver 42 receives the optical signal emitted by the transmitter 41, the corresponding counter stops timing and outputs timing data. Among them, the output objects of the timing data include but are not limited to a display screen, a computer, and a printer.
[0021] In this embodiment, the rotating transmission member 121 rotates one circle, the linear moving component 122 completes one lifting, the induction magnetic block 123 is set on the rotating transmission member 121, and the Hall sensor 13 is fixed at a preset position. Since the rotation stroke position of the rotating transmission member 121 and the moving position (including direction parameters) of the linear moving component 122 can correspond one to one, the Hall sensor 13 can be used to detect that the rotating transmission member 121 rotates to the preset position to determine that the hanging basket 2 is in an upward moving state. The rotating transmission member 121 can be a cam or a crank, and the cam push rod mechanism or the crank slider mechanism is used to achieve the above function. In this embodiment, the rotating transmission member 121 is an eccentric wheel, and the lower end of the linear moving component 122 is in contact with the upper end of the eccentric wheel.
[0022] In other embodiments, the motion state sensor includes an acceleration sensor (not shown) installed on the hanging basket 2. When the acceleration sensor receives a signal of upward acceleration movement, it determines that the hanging basket 2 is in a preset ascending stroke.
[0023] The principle of the automatic sensing device for disintegration time limit endpoint of the present embodiment is as follows: the pill placed in the tube body 21 sinks to the bottom of the tube body 21, and due to the setting of the conical screen cover 22, the pill will automatically occupy the center position of the conical screen cover 22 due to gravity, and just block the launch port of the transmitter 41 at this time. When the disintegration experiment is carried out, when the hanging basket 2 moves upward, the pill will fit with the conical screen cover 22, and it can be ensured that the undisintegrated pill blocks the launch port of the transmitter 41, so that the receiver 42 cannot detect the light signal emitted by the transmitter 41; when the pill is completely disintegrated, at this time, there is no shielding between the transmitter 41 and the receiver 42, and the receiver 42 can receive the light signal, so as to start and stop timing, output timing data, and obtain the disintegration time limit endpoint time. It should be noted that the reciprocating frequency of the up and down movement of the hanging basket 2 specified in the Pharmacopoeia is 30 to 32 times per minute, so the theoretical error of the disintegration time limit timing of the automatic sensing device for disintegration time limit endpoint of the present embodiment is 1 second. Therefore, the automatic sensing device for disintegration endpoint of the present embodiment can realize the automatic timing of the disintegration endpoint of the drug to be tested, saving manpower, and has the advantages of low manufacturing cost, simple control principle and good reliability compared with the existing technical solutions for automatic detection of disintegration endpoint. Among them, the photoelectric sensor 4 is preferably an underwater infrared photoelectric sensor.
[0024] Combination Figures 5 to 7As shown in the figure, in this embodiment, it further includes a transmitter mounting bracket 5. The transmitter mounting bracket 5 is installed at the lower end of the pipe body 21, and the transmitter mounting bracket 5 is connected to the pipe body 21. The transmitter mounting bracket 5 includes a base 51. There is a mounting counterbore 511 at the bottom of the base 51. The emitting end of the transmitter 41 is arranged in the mounting counterbore 511. A light-transmitting through-hole 512 penetrates through the top of the mounting counterbore 511, and the light-transmitting through-hole 512 corresponds to the emitting port of the transmitter 41. The aperture of the light-transmitting through-hole 512 is smaller than the sieve holes of the conical screen cover 22. The aperture size of the sieve holes of the disintegrator is the size specified in the Pharmacopoeia, such as 2 mm. When the particles after the pill disintegrates are smaller than the sieve holes of the conical screen cover 22, it is considered that the disintegration is completed. Therefore, the light-transmitting through-hole 512 is smaller than the sieve holes of the conical screen cover 22, which can ensure that the pills that have not completed disintegration can cover the light-transmitting through-hole 512. The light-transmitting through-hole 512 is arranged vertically and penetratingly. The arrangement of the light-transmitting through-hole 512 and the mounting counterbore 511 can prevent the diffuse reflection of the optical signal emitted by the transmitter 41, resulting in the receiver 42 receiving the optical signal in advance and causing errors. In this embodiment, the mounting counterbore 511 is threadedly connected to the transmitter 41, and the light-transmitting through-hole 512 corresponds to the axis position of the pipe body 21.
[0025] Combined with Figure 7 As shown in the figure, in this embodiment, a conical fitting surface 513 is provided at the upper end of the base 51. The lower end of the conical bottom surface of the conical screen cover 22 is fitted to the conical fitting surface 513. A limiting platform 5134 extends from the center of the conical fitting surface 513, and the edge of the lower end opening of the conical screen cover 22 is fitted to the limiting platform 5134. In this embodiment, the transmitter mounting bracket 5 further includes a collar 52. The collar 52 is arranged above the base 51. A group of connecting plates 53 are circumferentially provided at the lower end of the collar 52, and the bottom of the connecting plates 53 is connected to the base 51. The collar 52 is sleeved on the outer wall of the pipe body 21. By connecting the collar 52 and the base 51 through the connecting plates 53, the overall shape of the transmitter mounting bracket 5 is a hollow frame type, which can ensure the flow of the solution.
[0026] Combined with Figure 5As shown, in this embodiment, the conical screen cover 22 includes a conical bottom 221 and an annular sleeve 222 that are integrally connected. The conical bottom 221 is disposed below the annular sleeve 222, and the annular sleeve 222 is sleeved on the outer wall of the tube body 21. The conical surface inside the conical bottom 221 is in contact with the bottom of the tube body 21 to achieve the limit of the conical screen cover 22 relative to the tube body 21. When the conical bottom 221 is separated from the bottom edge of the tube body 21, the annular sleeve 222 can prevent a gap from being generated between the conical screen cover 22 and the tube body 21, so that the pills inside the tube body 21 do not leak out through the gap. In this embodiment, a limiting groove portion is provided on the inner wall of the collar 52, and the top end of the annular sleeve 222 is disposed in the limiting groove portion on the inner wall of the collar 52. Therefore, in this embodiment, the entire conical screen cover 22 is embedded between the collar 52 and the conical fitting surface 513 of the transmitter mounting bracket 5, and the overall fixing effect is reliable. When the hanging basket 2 reciprocates up and down, it can effectively prevent the conical screen cover 22 from falling off relative to the transmitter mounting bracket 5.
[0027] Combined with Figure 4 and Figure 6 As shown, in this embodiment, the hanging basket 2 includes an upper limit disk 23 and a lower limit disk 24. The upper limit disk 23 is disposed at the upper end of a group of tube bodies 21, and a group of tube bodies 21 are passed through the lower limit disk 24. Limiting holes adapted to the tube bodies 21 are provided on the upper limit disk 23 and the lower limit disk 24; it further includes a connecting rod 25 that penetrates through the upper limit disk 23 and the lower limit disk 24. A group of positioning nuts 251 are sleeved on the outer wall of the connecting rod 25, and the positioning nuts 251 achieve the axial positioning of the upper limit disk 23 and the lower limit disk 24 relative to the connecting rod 25. The upper end of the connecting rod 25 is connected to the lifting drive device 12. By driving the connecting rod 25 through the lifting drive device 12, the overall up and down movement of the hanging basket 2 is realized. It should be noted that a radially inward extending flange is provided at the upper end of the limiting hole corresponding to the tube body 21 on the upper limit disk 23 to achieve the limit of the upper end of the tube body 21.
[0028] Combined with Figure 6 and Figure 7 As shown, in this embodiment, the connecting rod 25 is a hollow tube body with openings at both ends, and the lower end of the connecting rod 25 extends to correspond to the transmitter 41. The hollow tube body-shaped connecting rod 25 is used to pass through the wires of a group of transmitters 41 to prevent the wires of the transmitters 41 from swinging, winding, and interfering when the hanging basket 2 moves up and down. In this embodiment, a group of wire grooves 252 are circumferentially provided at the lower end of the connecting rod 25, and a group of wire grooves 252 correspond to a group of transmitters 41 one by one. A limit cap 253 is connected to the bottom of the connecting rod 25. The wire grooves 252 are used to lead out the wires, and the limit cap 253 can limit the lower end of the wires.
[0029] Combined with Figure 4As shown in the figure, in this embodiment, the hanging basket 2 further includes a supporting plate 26. The supporting plate 26 is connected below the lower limit disc 24 by a set of bolts, and the upper end of the supporting plate 26 is in contact with the bottom surface of the base 51. The supporting plate 26 limits the bottom of the transmitter mounting bracket 5 through bolts and nuts. As a whole, it can improve the connection firmness of the transmitter mounting bracket 5 and the conical screen cover 22 relative to the pipe body 21. In this embodiment, the top end of the collar 52 is in contact with the upper limit disc 23. And as a whole, it has detachability, which is convenient for cleaning and maintenance.
[0030] Combined with Figure 5 and Figure 6 As shown in the figure, in this embodiment, a floating head 421 is sleeved outside the receiver 42. The outer edge shape of the floating head 421 is adapted to the inner edge of the pipe body 21. The receiving port of the receiver 42 extends below the floating head 421, and a set of through notches 422 are provided on the outer edge of the floating head 421. It should be noted that when the pipe body 21 is immersed in the beaker 3, the top end of the pipe body 21 is always above the water surface of the beaker 3. The receiver 42 is installed on the floating head 421. When in use, when the hanging basket 2 is immersed in the solution in the beaker 3, the floating head 421 is integrally placed into the pipe body 21, and the floating head 421 floats above the solution in the pipe body 21. At this time, the receiving port of the receiver 42 is always immersed below the liquid level in the pipe body 21. Therefore, it can be ensured that during the process of moving the hanging basket 2 up and down, the medium between the transmitter 41 and the receiver 42 is only the solution inside the pipe body 21. It is avoided that the receiver 42 leaves the water surface, resulting in refraction of the light emitted from the transmitter 41, so that the receiver 42 does not receive the signal in time. Therefore, the accuracy of the end-point timing of the disintegration time limit can be ensured. It should be noted that if the receiver 42 is directly sunk to the bottom of the pipe body 21, it will squeeze the moving space of the pill placed in the pipe body 21, thus affecting the disintegration test result. Among them, the outer edge shape of the floating head 421 is adapted to the inner edge of the pipe body 21, which can ensure the positioning of the receiving port of the receiver 42. In this embodiment, the positions of the receiving port and the transmitting port of the receiver 42 and the transmitter 41 correspond to the axis core of the pipe body 21. The notches 422 are provided to prevent the floating head 421 from causing airtight blockage to the pipe body 21.
[0031] Combined with Figure 1 and Figure 2 As shown in the figure, in this embodiment, an installation plate 254 is provided at the top of the connecting rod 25, and a wire through hole 255 is provided on the installation plate 254 for threading the wire extending from the receiver 42. The linear movement assembly 122 includes a lifting rod 124. The rotary transmission member 121 extends from the upper end of the disintegrator main body 1. An extension plate 125 is provided on the rotary transmission member 121. A pair of suspension rods 126 are fixed on the linear movement assembly 122, and a pair of induction magnetic blocks 123 are connected to the installation plate 254.
[0032] The technical principles of the present invention have been described in connection with specific embodiments above. These descriptions are only for explaining the principles of the present invention and should not be construed in any way as limiting the scope of protection of the present invention. Based on the explanations herein, those skilled in the art can readily conceive of other specific embodiments of the present invention without creative efforts, and these embodiments will fall within the scope of protection of the present invention.
Claims
1. An automatic sensing device for disintegration time endpoint, characterized in that: include: The disintegration instrument body includes a hanging basket and a lifting drive device for driving the hanging basket to lift and lower back and forth; A pipe body installed on the hanging basket, with a conical mesh cover at the bottom of the pipe body, the diameter of the upper end of the conical mesh cover is larger than the diameter of the lower end; The photoelectric sensor includes a transmitter and a receiver. The transmitter is installed below the conical mesh cover and its transmitting port is directly opposite to the bottom opening of the conical mesh cover. When the drug sinks to the bottom of the conical mesh cover before the drug is completely disintegrated, it can block the light signal emitted by the transmitter. The receiver is arranged above the conical mesh cover and its receiving port is directly opposite to the transmitting port of the transmitter. The motion state sensor is used to detect whether the motion state of the hanging basket is in a preset ascending stroke.
2. The automatic disintegration endpoint sensing device according to claim 1, characterized in that: The lifting drive device comprises a rotating transmission member and a linear moving assembly, wherein the rotating transmission member is in transmission connection with the linear moving assembly, the linear moving assembly is connected with the hanging basket, and an induction magnetic block is arranged on the rotating transmission member; The motion state sensor includes a Hall sensor, which is arranged on one side of the sensing magnetic block. When the rotating transmission member drives the sensing magnetic block to rotate to a position corresponding to the Hall sensor, the linear moving component drives the hanging basket to be in a preset ascending stroke.
3. The automatic sensing device for disintegration end point according to claim 1, characterized in that: The motion state sensor comprises an acceleration sensor installed on the hanging basket. When the acceleration sensor receives a signal of upward acceleration movement, it is determined that the hanging basket is in a preset ascending stroke.
4. The automatic disintegration endpoint sensing device according to claim 1, characterized in that: It also includes a transmitter mounting frame, which is installed at the lower end of the tube body and connected to the tube body. The transmitter mounting frame includes a base, a mounting countersunk hole is provided at the bottom of the base, and the transmitter transmitting end is arranged in the mounting countersunk hole. A light-transmitting through hole is penetrated at the top of the mounting countersunk hole, and the light-transmitting through hole corresponds to the transmitting port of the transmitter.
5. The automatic disintegration endpoint sensing device according to claim 1, characterized in that: The hanging basket comprises an upper limit plate and a lower limit plate, wherein the upper limit plate is arranged at the upper end of a group of tube bodies, a group of tube bodies are penetrated on the lower limit plate, and the upper limit plate and the lower limit plate are provided with limit holes adapted to the tube bodies; It also includes a connecting rod, which passes through the upper limit plate and the lower limit plate. The outer wall of the connecting rod is sleeved with a group of positioning nuts, and the positioning nuts realize the axial positioning of the upper limit plate and the lower limit plate relative to the connecting rod. The upper end of the connecting rod is connected to the lifting drive device.
6. The automatic disintegration endpoint sensing device according to claim 5, characterized in that: The connecting rod is a hollow tube with openings at both ends, and the lower end of the connecting rod extends to correspond to the launcher.
7. An automatic sensing system for disintegration time endpoint, characterized in that: include: A lifting drive module, used to control the lifting drive device to drive the hanging basket to lift and lower back and forth; The motion state sensing module is used to detect that the hanging basket is in a preset ascending stroke to activate the photoelectric sensor; Disintegration completion confirmation module, after the photoelectric sensor is activated, it detects whether the drug has completed disintegration; Timing module, used to measure the time from the start to the completion of disintegration.
8. A method for automatically sensing the end point of disintegration time, characterized in that: The automatic sensing device for disintegration time endpoint according to claim 1 comprises the following steps: The medicine is loaded into the tube of the hanging basket and placed between the conical mesh cover and the receiver; The tube body is immersed in the solution and the lifting driving device is used to drive the hanging basket to move up and down reciprocatingly; The photoelectric sensor is activated when the hanging basket is detected to be in the preset ascending stroke; When the receiver receives the light signal sent by the transmitter, it is determined that the drug has completed disintegration.
Citation Information
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