Subtilisin variants and methods related thereto
By substitution of subtilis protease at specific amino acid positions, a protease variant with improved stability and cleaning performance was developed, solving the problem of degradation of the cleaning performance of proteases under high temperature and long-term use in the prior art, and achieving more efficient dirt removal and stability.
CN120112635APending Publication Date: 2025-06-06DANISCO US INC
283 Cites 0 Cited by
Patent Information
- Application Number
- CN202380063068.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2023-03-28
- Filing Date
- 2023-08-29
- Publication Date
- 2025-06-06
AI Technical Summary
Technical Problem
Existing subtilisin has shortcomings in stability and soil removal, especially in high temperatures and long-term use, resulting in a degradation of cleaning performance.
Method used
A subtilisin variant was developed that improves the stability and cleaning performance of the protease by substitution at specific amino acid positions. Specifically, this variant has improved net charge and stability at pH 8 and is able to maintain high activity at high temperatures.
Benefits of technology
This subtilisin variant significantly improves detergent stability and dirt removal capabilities, enabling efficient cleaning performance under extended use and high temperature conditions.
✦ Generated by Eureka AI based on patent content.
Abstract
Disclosed herein are one or more subtilisin variants, nucleic acids encoding the same, and compositions and methods related to production and use thereof, the one or more subtilisin variants include one or more subtilisin variants having improved stability and / or soil removability as compared to one or more reference subtilisins.
Need to check novelty before this filing date? Find Prior Art