Oral traditional Chinese medicine composition for treating wind-evil cold and preparation method thereof

Abstract

The invention discloses an oral traditional Chinese medicine composition for treating wind-evil cold and a preparation method, and relates to the technical field of medicine research, the oral traditional Chinese medicine composition comprises 10g of ephedra, 10g of bitter apricot kernel, 10g of blackberry lily, 10g of puffball, 10g of thunberg fritillary bulb, 10g of platycodon grandiflorum, 10g of cynanchum glaucescens, 10g of radix peucedani, 20g of scutellaria baicalensis, 20g of solanum lyratum, 10g of aster tataricus and 10g of tussilago farfara. According to the orally-taken traditional Chinese medicine composition for treating wind-evil cold and the preparation method, the traditional Chinese medicine composition is prepared from 10g of ephedra, 10g of semen armeniacae amarae, 10g of rhizoma belamcandae, 10g of puffball, 10g of thunberg fritillary bulb, 10g of platycodon grandiflorum, 10g of cynanchum glaucescens, 10g of radix peucedani, 20g of scutellaria baicalensis, 20g of solanum lyratum, 10g of radix asteris and 10g of tussilago farfara, and when cold and heat differentiation of cold symptoms of a patient is not obvious and the cold with wind-evil as a main component begins, the curative effect of the wind-evil dispelling formula is remarkable; in addition, although the wind-ventilating and evil-dispelling prescription is mainly used for wind-ventilating and evil-dispelling, the wind-ventilating and evil-dispelling prescription is also used for wind-ventilating and evil-dispelling and lung-heat-clearing, has a good clinical curative effect on patients who are hot in physique and easy to become heat after wind evil enters the body, and plays a positive role in improving the clinical level of young doctors.

Description

Technical Field

[0001] The present invention relates to the technical field of drug research, and specifically to a traditional Chinese medicine composition for orally treating wind-caused colds and a preparation method thereof. Background Art

[0002] A cold is an exogenous disease that is caused by being exposed to wind pathogens or epidemic viruses, leading to the dysfunction of the lung-defense function, and presenting with main clinical manifestations such as nasal congestion, runny nose, sneezing, headache, aversion to cold, fever, and general discomfort. It can occur throughout the year, but is more common in winter and spring. There are differences between common colds and epidemic colds. Traditional Chinese medicine colds are basically the same as Western medicine colds. A common cold is equivalent to a common cold or upper respiratory tract infection in Western medicine, and an epidemic cold is equivalent to influenza in Western medicine. It is a common and frequently-occurring disease, with a wide incidence and a high individual recurrence rate, which cannot be compared with any other disease. In Western medicine treatment of colds, in addition to antibacterial and antiviral drugs, symptomatic treatment is mainly carried out. Antipyretic and analgesic drugs can relieve symptoms such as fever, muscle soreness, and headache, antihistamines can relieve symptoms such as sneezing and rhinorrhea, and cough suppressants can be taken for severe coughing. For patients with nasal congestion and nasal mucosa congestion and edema, drugs such as pseudoephedrine hydrochloride can be used. In traditional Chinese medicine, it is believed that the location of a cold is in the lung-defense, and its basic pathogenesis is that exogenous pathogens affect the dysfunction of the lung-defense function, leading to disharmony of the defensive aspect and failure of the lung to disperse and descend, especially disharmony of the defensive aspect being the main aspect. The six exogenous pathogenic factors or epidemic pathogens led by wind invade the human body either through the mouth and nose or through the skin and hair. Because wind is light and floating, as stated in "Plain Questions - Taiyin and Yangming Treatise": "Those who are injured by wind are first affected from above." The lung is the canopy of the zang-fu organs, with the highest position, opening orifices in the nose, responsible for respiration, externally governing the skin and hair, and being delicate in nature and intolerant of pathogen invasion. Therefore, when exogenous pathogens invade through the mouth and nose or the skin and hair, the lung-defense is the first to be affected. Due to the differences in the six qi of the four seasons and the differences in the physical constitutions of individuals, there are different syndromes such as wind-cold, wind-heat, and summer-heat in clinical practice, and the transformation or complexity of cold and heat can also be seen during the course of the disease. Traditional Chinese medicine often uses "releasing the exterior to dispel pathogens, promoting the lung qi to circulate and dredge, strengthening the healthy qi to dispel pathogens" as the main treatment methods.

[0003] Currently, the main problems in the clinical treatment of wind-caused colds are as follows: 1. When many young clinicians follow the syndrome differentiation and treatment of colds in traditional Chinese internal medicine, they mainly focus on the syndrome differentiation of wind-cold and wind-heat colds. The key points in the prescription are mostly on pungent-warm exterior-releasing and pungent-cool exterior-releasing, blindly using pungent-warm cold-dispelling drugs and cold-cooling heat-clearing drugs. However, in the initial stage of being affected by wind pathogens, traditional Chinese medicine should mainly focus on dispersing wind pathogens. 2. Many patients choose to buy proprietary Chinese medicines in pharmacies for treatment when they first catch a cold, but without the guidance of a professional traditional Chinese medicine doctor for purchasing drugs, patients are very likely to use the wrong drugs, such as using pungent-cool exterior-releasing drugs for wind-cold colds. Summary of the Invention

[0004] Aiming at the deficiencies of the prior art, the present invention provides a traditional Chinese medicine composition for orally treating wind-caused colds and a preparation method thereof, solving the problems raised in the above background art.

[0005] To achieve the above object, the present invention is realized through the following technical solutions: A traditional Chinese medicine composition for oral administration in the treatment of wind-cold colds, comprising 10 g of Ephedrae Herba, 10 g of Armeniacae Semen Amarum, 10 g of Belamcandae Rhizoma, 10 g of Lasiosphaera seu Calvatia, 10 g of Thunberg Fritillary Bulb, 10 g of Platycodonis Radix, 10 g of Cynanchi Stauntonii Radix, 10 g of Peucedani Radix, 20 g of Scutellariae Radix, 20 g of Solani Lyrati Herba, 10 g of Asteris Radix, and 10 g of Tussilaginis Flos.

[0006] Optionally, the Ephedrae Herba is the monarch drug, pungent and slightly bitter in taste, warm in nature, with the specific effects of inducing sweating and relieving exterior syndrome, dispersing lung qi and relieving asthma, and promoting diuresis and alleviating edema, and can relieve exterior cold.

[0007] Optionally, the Armeniacae Semen Amarum is the minister drug, bitter in taste, slightly warm in nature, with the effects of lowering qi and relieving cough and asthma, and moistening the intestines and promoting defecation. There are sweet and bitter almonds. Sweet almonds have stronger effects of moistening the lungs and promoting defecation, while bitter almonds have stronger qi-lowering power. Therefore, bitter almonds are selected. Combined with Ephedrae Herba, one ascending and one descending, they can promote the flow of lung qi.

[0008] Belamcandae Rhizoma is bitter in taste, cold in nature, slightly toxic, with the effects of clearing heat and detoxifying, dissipating nodules and relieving inflammation, reducing swelling and alleviating pain, and relieving cough and resolving phlegm. It can relieve sore throat symptoms when used in this formula.

[0009] Optionally, the Thunberg Fritillary Bulb is bitter in taste, cold in nature, with the effects of clearing heat and resolving phlegm, detoxifying and dissipating nodules and discharging carbuncles. The Thunberg Fritillary Bulb has stronger heat-clearing power and is more inclined to clearing lung heat, while the Sichuan Fritillary Bulb has insufficient heat-clearing power but is sweet in taste and moist in nature, being more inclined to moistening the lungs and relieving cough. Therefore, the Thunberg Fritillary Bulb is selected in this formula to clear lung heat.

[0010] Optionally, the Platycodonis Radix is bitter and pungent in taste, neutral in nature, with the effects of dispersing lung qi and relieving sore throat, resolving phlegm, and discharging pus. In this formula, it can disperse lung qi and expel wind pathogens. If there is sore throat and expectoration, it can also relieve sore throat and resolve phlegm. The Platycodonis Radix enters the lung meridian and can lead the medicine upward.

[0011] Optionally, the Cynanchi Stauntonii Radix is pungent and bitter in taste, slightly warm in nature, with the effects of lowering qi, eliminating phlegm, and relieving cough.

[0012] Peucedani Radix is bitter and pungent in taste, slightly cold in nature, with the effects of lowering qi and resolving phlegm, dispersing wind and clearing heat. The combination of Cynanchi Stauntonii Radix and Peucedani Radix, together with Platycodonis Radix, one ascending and one descending, can make the qi mechanism smooth, contribute to dispersing lung qi, and at the same time both can eliminate phlegm. Peucedani Radix clears lung heat.

[0013] Optionally, the Scutellariae Radix is bitter in taste, cold in nature, with the effects of clearing heat and drying dampness, purging fire and detoxifying, stopping bleeding, and preventing miscarriage.

[0014] Solani Lyrati Herba is bitter in taste, slightly cold in nature, with the effects of clearing heat and detoxifying, promoting diuresis, and dispelling wind-dampness. Both can clear lung heat.

[0015] Optionally, the Asteris Radix is pungent in taste, bitter and warm in nature, with the effect of resolving phlegm and relieving cough. Asteris Radix is pungent and dispersing, bitter and purging, with relatively strong phlegm-resolving effect but relatively weak cough-relieving power.

[0016] Optionally, the coltsfoot flower is pungent in flavor and warm in nature, and has the efficacy of relieving cough and resolving phlegm. The effects of coltsfoot flower and aster are similar, and both can resolve phlegm and relieve cough. Therefore, they are often used in combination clinically. However, the cough-relieving effect of coltsfoot flower is stronger, while the phlegm-resolving effect is weaker; aster is just the opposite, and the combination of the two has a good effect on resolving phlegm and relieving cough.

[0017] A preparation method of a traditional Chinese medicine composition for orally treating wind-cold cold, comprising the following steps:

[0018] S1: Take 10g of ephedra, 10g of bitter apricot kernels, 10g of belamcanda chinensis, 10g of lasiosphaera seu calvatia, 10g of fritillaria thunbergii, 10g of platycodon grandiflorum, 10g of stemona japonica, 10g of peucedanum praeruptorum, 20g of scutellaria baicalensis, 20g of solanum lyratum, 10g of aster, and 10g of coltsfoot flower. First, soak the medicine in cold water for 30 - 60 minutes, and the amount of water for soaking should be appropriate to submerge the medicine surface by 3cm - 5cm;

[0019] S2: Place the medicine on the fire and bring it to a boil with strong fire. After boiling, change to slow fire and keep it in a slightly boiling state to slow down the evaporation of water and facilitate the dissolution of active ingredients. Start timing after changing to slow fire. The diaphoretic medicine is also called the medicine for treating colds. Decoct it for about 15 - 20 minutes, and other medicines are generally decocted for 40 - 50 minutes;

[0020] S3: Pour out the medicinal liquid decocted for the first time, add an appropriate amount of hot water. The water should not be too much, and it is appropriate to just submerge the medicinal materials by 2cm - 3cm for the second decoction. The decocting time is about 20 - 30 minutes. Take it once in the morning and once in the evening, and take it warm half an hour after meals.

[0021] The present invention provides a traditional Chinese medicine composition for orally treating wind-cold cold and a preparation method thereof, having the following beneficial effects:

[0022] 1. The traditional Chinese medicine composition for orally treating wind-cold cold and the preparation method thereof are composed of 10g of ephedra, 10g of bitter apricot kernels, 10g of belamcanda chinensis, 10g of lasiosphaera seu calvatia, 10g of fritillaria thunbergii, 10g of platycodon grandiflorum, 10g of stemona japonica, 10g of peucedanum praeruptorum, 20g of scutellaria baicalensis, 20g of solanum lyratum, 10g of aster, and 10g of coltsfoot flower. When the cold symptoms of the patient are not significantly differentiated between cold and heat and it is the initial stage of a cold mainly caused by wind pathogen, the curative effect of the formula for dispersing wind pathogen is remarkable; in addition, although the formula for dispersing wind pathogen mainly focuses on dispersing wind pathogen, it also combines dispersing wind pathogen and clearing lung heat. For patients with a relatively hot constitution who are prone to heat transformation after wind pathogen invades the body, it has good clinical curative effects, which has a positive effect on improving the clinical level of young doctors. Brief Description of the Drawings

[0023] Figure 1 It is a schematic diagram of the grading of common cold symptoms of the present invention;

[0024] Figure 2 It is a schematic diagram of the comparison of the overall symptom remission rates of two groups in the research experiment of the present invention after 5 days of treatment;

[0025] Figure 3 It is a schematic diagram for comparing the integral values of main symptoms, secondary symptoms, and overall symptoms of two groups after 5 days of treatment in the research experiment of the present invention;

[0026] Figure 4 It is a schematic diagram for comparing the clinical curative effects of two groups after 5 days of treatment with the present invention. Detailed implementation manners

[0027] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments.

[0028] Please refer to Figures 1 to 4 , the present invention provides a technical solution: a traditional Chinese medicine composition for orally treating wind-cold colds, including 10 g of Ephedrae Herba, 10 g of Armeniacae Semen Amarum, 10 g of Belamcandae Rhizoma, 10 g of Lasiosphaerae Fructificatio, 10 g of Thunbergii Fritillaria Bulb, 10 g of Platycodonis Radix, 10 g of Cynanchi Stauntonii Radix, 10 g of Peucedani Radix, 20 g of Scutellariae Radix, 20 g of Solani Lyrati Herba, 10 g of Asteris Radix, and 10 g of Tussilaginis Flos.

[0029] The Ephedrae Herba is the monarch drug, pungent and slightly bitter in taste, warm in nature, with the specific effects of inducing sweating to relieve exterior syndrome, dispersing lung qi to relieve asthma, and promoting diuresis to alleviate edema, and can relieve exterior cold.

[0030] The Armeniacae Semen Amarum is the ministerial drug, bitter in taste, slightly warm in nature, with the effects of lowering qi to relieve cough and asthma and moistening the intestines to promote defecation. There are sweet and bitter Armeniacae Semen Amarum. The sweet Armeniacae Semen Amarum has stronger effects of moistening the lungs and promoting defecation, while the bitter Armeniacae Semen Amarum has a stronger effect of lowering qi. Therefore, the bitter Armeniacae Semen Amarum is selected. Combined with the Ephedrae Herba, one ascending and one descending, it can dredge the lung qi. Belamcandae Rhizoma is bitter in taste, cold in nature, slightly toxic, with the effects of clearing heat and detoxifying, dissipating stasis and anti-inflammatory, relieving swelling and pain, and relieving cough and resolving phlegm. It can be used in this formula to relieve sore throat symptoms.

[0031] The Thunbergii Fritillaria Bulb is bitter in taste, cold in nature, with the effects of clearing heat, resolving phlegm, relieving cough, and detoxifying and dissipating stasis and resolving carbuncles. The Thunbergii Fritillaria Bulb has a stronger heat-clearing power and is more inclined to clear lung heat, while the cirrhosae Fritillaria Bulb has insufficient heat-clearing power but is sweet in taste and moist in nature, and is more inclined to moisten the lungs and relieve cough. Therefore, the Thunbergii Fritillaria Bulb is selected in this formula to clear lung heat.

[0032] The Platycodonis Radix is bitter and pungent in taste, neutral in nature, with the effects of dispersing lung qi, relieving sore throat, resolving phlegm, and discharging pus. In this formula, it can disperse lung qi and expel wind-cold. If there is sore throat and expectoration, it can also relieve sore throat and resolve phlegm. The Platycodonis Radix belongs to the lung meridian and can lead the drug upward.

[0033] The Cynanchi Stauntonii Radix is pungent and bitter in taste, slightly warm in nature, with the effects of lowering qi, dissipating phlegm, and relieving cough;

[0034] The Peucedani Radix is bitter and pungent in taste, slightly cold in nature, with the effects of lowering qi and resolving phlegm, and dispersing wind and clearing heat. The combination of Cynanchi Stauntonii Radix and Peucedani Radix with the Platycodonis Radix, one ascending and one descending, can make the qi movement smooth, contribute to dispersing lung qi, and at the same time both can dissipate phlegm, and the Peucedani Radix clears lung heat.

[0035] Scutellaria baicalensis Georgi is bitter in taste and cold in nature, and has the effects of clearing heat and drying dampness, purging fire and detoxifying, stopping bleeding, and preventing miscarriage; Solanum lyratum Thunb. is bitter in taste and slightly cold in nature, and has the effects of clearing heat and detoxifying, promoting diuresis, and dispelling wind-dampness. Both can clear lung heat.

[0036] The aster is pungent in taste, bitter and warm in nature, and has the effect of resolving phlegm and relieving cough. The aster is pungent and dispersing, bitter and discharging, with a relatively strong expectorant effect and a relatively weak cough-relieving effect.

[0037] Tussilago farfara L. is pungent in taste and warm in nature, and has the effect of relieving cough and resolving phlegm. The effects of Tussilago farfara L. and aster are similar, both can resolve phlegm and relieve cough. Therefore, they are often used together in clinical applications. However, the cough-relieving effect of Tussilago farfara L. is stronger, while the expectorant effect is weaker; the aster is just the opposite. The combination of the two has a good effect on resolving phlegm and relieving cough.

[0038] A preparation method of a traditional Chinese medicine composition for oral administration in the treatment of wind-cold influenza and the decocting method of traditional Chinese medicine include the following steps: First step, first soak the medicine in cold water for 30 - 60 minutes, and the amount of water for soaking should be appropriate to submerge the medicine surface by 3 cm - 5 cm;

[0039] Second step, put the medicine on the fire, bring it to a boil with strong fire, and then change to slow fire after boiling, keep it in a slightly boiling state, slow down the evaporation of water, which is beneficial to the dissolution of active ingredients. Start timing after changing to slow fire. The diaphoretic medicine is also called the medicine for treating colds, and it is decocted for about 15 - 20 minutes, and other medicines are generally decocted for 40 - 50 minutes;

[0040] Third step, pour out the decocted liquid from the first decoction, add an appropriate amount of hot water, the amount of water should not be too much, just enough to submerge the medicinal materials by 2 cm - 3 cm, and conduct the second decoction. The decocting time is about 20 - 30 minutes. Take it once in the morning and once in the evening, and take it warm half an hour after meals.

[0041] The experimental process is as follows:

[0042] In this research experiment, 120 patients with wind-cold influenza were admitted. Diagnostic criteria: The western medicine diagnostic criteria refer to the "Expert Consensus on the Standard Diagnosis and Treatment of Common Cold" in 2012 edition, and relevant contents in "Respiratory Medicine" and "Internal Medicine", etc. The traditional Chinese medicine diagnosis refers to the diagnostic criteria of colds in the 5th edition of "Internal Medicine".

[0043] Inclusion criteria: newly diagnosed patients, regardless of gender; aged 18 - 65 years old; meeting the western and traditional Chinese medicine diagnostic criteria; not having taken drugs with therapeutic effects on common cold; patients having the intention to participate and signing the informed consent form. Exclusion criteria: not meeting the inclusion criteria; having severe heart, lung, liver, kidney, nerve, and blood diseases; having participated in other trials recently; being pregnant or lactating; having mental diseases; being unable to adhere to the whole course or refusing to take traditional Chinese medicine; being allergic or having a hypersensitive body to the drugs in this research, etc.

[0044] Numbered in the order of medical treatment and randomly divided into two groups (using the random number table in Appendix 16 of the textbook "Medical Statistics"), with 60 cases in each group, namely the treatment group and the control group. Among the 120 included patients, there was no dropout in the experimental group, and 3 cases dropped out in the control group.

[0045] 1. Research method: This study adopted the method of randomized controlled clinical trials.

[0046] 1.1. Control group: Given 999 Ganmaoling Granules (produced by China Resources Sanjiu Medical & Pharmaceutical Co., Ltd., approval number of traditional Chinese medicine Z44021940) orally, 3 times a day, 1 packet each time, and taken continuously for 5 days as a course of treatment.

[0047] 1.2. Observation group: Traditional Chinese medicine prescription: 10g of Ephedra, 10g of Bitter Apricot Seed, 10g of Belamcanda Root, 10g of Lasiosphaera seu Calvatia, 10g of Thunberg Fritillary Bulb, 10g of Platycodon Root, 10g of Cynanchum stauntonii, 10g of Peucedanum praeruptorum, 20g of Scutellaria baicalensis, 20g of Solanum lyratum, 10g of Aster tataricus, 10g of Tussilago farfara. Decoct with water, strictly follow the decoction method, once in the morning and once in the evening, take 100ml each time, take it warm half an hour after meals, and take it continuously for 5 days as a course of treatment.

[0048] 1.3. Observation indicators:

[0049] 1.3.1 Main efficacy indicators: ① The overall symptom remission rate after 5 days of treatment; ② The total score of main symptoms after 5 days of treatment.

[0050] 1.3.2 Secondary efficacy indicators: ① The score of secondary symptoms and the total symptom score after 5 days of treatment; ② The overall symptom remission time within 5 days of treatment; ③ The curative effect of traditional Chinese medicine syndromes after 5 days of treatment.

[0051] 1.3.3 Method for evaluating efficacy indicators: The overall symptom remission rate = (the number of cases with alleviated overall symptoms / the total number of evaluable cases) × 100%; The grading and scoring criteria for each symptom were all quantified and graded according to the "Guidelines for Clinical Research of New Traditional Chinese Medicines" for "none, mild, moderate, severe" levels, and were scored according to the criteria of 0, 2, 4, 6 points for main symptoms and 0, 1, 2, 3 points for secondary symptoms respectively; The evaluation criteria for the curative effect of traditional Chinese medicine syndromes were formulated with reference to the "Guidelines for Clinical Research of New Traditional Chinese Medicines". The reduction rate of traditional Chinese medicine syndrome score = (score before treatment - score after treatment) / score before treatment × 100%. Clinical cure means that clinical symptoms and signs disappear, and the reduction rate of syndrome score ≥ 95%; Marked effect means that clinical symptoms and signs are significantly improved, 70% ≤ reduction rate of syndrome score < 95%; Effective means that clinical symptoms and signs are improved, 30% ≤ reduction rate of syndrome score < 70%; Ineffective means that clinical symptoms and signs are not significantly improved, and the reduction rate of syndrome score < 30%. The grading and quantification criteria for common cold symptoms are shown in Figure 1 .

[0052] 2. Data statistical method: Statistical analysis was performed using SAS statistical analysis software. All statistical data were subjected to two-sided tests, and a P value ≤ 0.05 was considered statistically significant. Measurement data conforming to a normal distribution were described using the mean ± standard deviation, and the t-test was used for between-group comparisons. For data not conforming to a normal distribution, the median and interquartile range were used for description. Qualitative data were described using frequency tables, percentages, or constituent ratios, and the χ2 test was used for between-group comparisons. The rank sum test was used for between-group ranked data. The efficacy indicators were statistically analyzed using both the full analysis set (FAS) and the per-protocol set (PPS).

[0053] 3. Results:

[0054] 3.1 Overall symptom remission rate after 5 days of treatment: After 5 days of treatment, the overall symptom remission rate in the experimental group was higher than that in the control group, and the difference was statistically significant (FAS χ2 = 11.1368, P < 0.01; PPS χ2 = 9.8502, P < 0.01). The analysis results of the two data sets were consistent, as shown in Figure 2 .

[0055] 3.2 Comparison of main symptom scores, secondary symptom scores, and total symptom scores after 5 days of treatment: After 5 days of treatment, the experimental group was significantly superior to the control group in improving the main symptom scores, secondary symptom scores, and total symptom scores, and the difference was statistically significant (P < 0.01). The analysis results of the two analysis sets were consistent, as shown in Figure 3 .

[0056] 3.3 Overall symptom remission time within 5 days: Among the patients in the experimental group, 53 cases had overall symptom remission within 5 days, and the remission time was 48 (48, 72) h. Among the control group, 40 cases had overall symptom remission, and the remission time was 48 (48, 72) h. There was no statistically significant difference in the overall symptom remission time within 5 days between the two groups.

[0057] 3.4 Efficacy of traditional Chinese medicine syndromes after 5 days of treatment;

[0058] The efficacy of traditional Chinese medicine syndromes in the experimental group was superior to that in the control group after 5 days of treatment (FAS χ2 = 20.2676; PPS χ2 = 17.7976, P < 0.01), and the difference was statistically significant. The analysis results of the two analysis sets were consistent, as shown in Figure 4 .

[0059] In summary, for the traditional Chinese medicine composition for orally treating wind-caused colds and its preparation method, when in use, take 10 g of Ephedrae Herba, 10 g of Armeniacae Semen Amarum, 10 g of Belamcandae Rhizoma, 10 g of Lasiosphaera seu Calvatia, 10 g of Thunbergii Fritillaria Bulb, 10 g of Platycodonis Radix, 10 g of Cynanchi Stauntonii Radix, 10 g of Peucedani Radix, 20 g of Scutellariae Radix, 20 g of Solani Lyrati Herba, 10 g of Asteris Radix, 10 g of Tussilaginis Flos. First, soak the herbs in cold water for 30 - 60 minutes. The amount of water for soaking should be appropriate to submerge the herbs by 3 cm - 5 cm. Place the herbs on the fire and bring to a boil over high heat. After boiling, switch to low heat and maintain a gentle boiling state to slow down the evaporation of water, which is beneficial to the dissolution of active ingredients. Start timing after switching to low heat. The diaphoretic herbs, also known as cold medications, are decocted for about 15 - 20 minutes, and other herbs are generally decocted for 40 - 50 minutes. Pour out the liquid obtained from the first decoction, add an appropriate amount of hot water. The amount of water should not be too much, just enough to submerge the herbs by 2 cm - 3 cm, and conduct the second decoction. The decoction time is about 20 - 30 minutes. Take it once in the morning and once in the evening, and take it warm half an hour after meals.

[0060] As mentioned above, the above is only the preferred specific implementation mode of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution of the present invention and its inventive concept, makes equivalent substitutions or changes, and all should be covered by the protection scope of the present invention.

Claims

1. A Chinese medicine composition for treating cold caused by wind pathogen, characterized in that: Including ephedra 10g, bitter almond 10g, belamcanda 10g, puffball 10g, thunbergia 10g, platycodon 10g, scutellaria 10g, peucedanum 10g, scutellaria 20g, white scutellaria 20g, aster 10g, coltsfoot 10g.

2. A Chinese medicine composition for treating colds caused by wind pathogens according to claim 1, characterized in that: The ephedra is the main drug, with a pungent and slightly bitter taste and a warm nature. It has the effects of inducing sweat and relieving exterior symptoms, promoting lung function and relieving asthma, promoting diuresis and reducing swelling, and can relieve exterior symptoms and dispel cold.

3. A Chinese medicine composition for treating colds caused by wind pathogens according to claim 1, characterized in that: The bitter almond is a ministerial drug, bitter in taste, slightly warm in nature, and has the effects of descending qi, relieving cough and asthma, and moistening the intestines and relieving constipation. Almonds are divided into sweet almonds and bitter almonds. Sweet almonds have stronger effects of moistening the lungs and moistening the intestines and relieving constipation, while bitter almonds have a strong ability to descend qi. Therefore, bitter almonds are selected, and combined with ephedra, one ascending and one descending, can promote the flow of lung qi. Belamcanda chinensis tastes bitter, is cold in nature, and slightly toxic. It has the effects of clearing away heat and detoxifying, dispersing nodules and relieving inflammation, reducing swelling and relieving pain, and relieving cough and resolving phlegm. It can be used in this prescription to relieve symptoms of sore throat.

4. A Chinese medicine composition for treating colds caused by wind pathogens taken orally according to claim 1, characterized in that: The Zhejiang Fritillaria is bitter in taste and cold in nature. It has the effects of clearing away heat, resolving phlegm and relieving cough, detoxifying, dispersing nodules and eliminating carbuncles. Zhejiang Fritillaria has a stronger heat-clearing ability and tends to clear the lungs and resolve phlegm, while Sichuan Fritillaria has insufficient heat-clearing ability, but tastes sweet and is moist in texture, and tends to moisten the lungs and relieve cough. Therefore, this prescription selects Zhejiang Fritillaria to clear the lungs and resolve phlegm.

5. A Chinese medicine composition for treating colds caused by wind pathogens taken orally according to claim 1, characterized in that: The Platycodon grandiflorum tastes bitter and pungent, and is neutral in nature. It has the effects of clearing the lungs, relieving sore throat, removing phlegm, and discharging pus. This prescription can clear the lungs and dispel wind evil. If there is sore throat and sputum, it can also relieve sore throat and remove phlegm. Platycodon grandiflorum belongs to the lung meridian and can lead the medicine upward.

6. A Chinese medicine composition for treating colds caused by wind pathogens according to claim 1, characterized in that: The white radix scutellariae tastes pungent and bitter, is slightly warm in nature, and has the effects of lowering qi, eliminating phlegm, and relieving cough; Peucedanum is bitter and pungent in taste and slightly cold in nature. It has the effects of descending qi, resolving phlegm, dispersing wind and clearing heat. White radix and Peucedanum together with Platycodon grandiflorum can make the qi flow smoothly and help to promote lung function. At the same time, both of them can eliminate phlegm and Peucedanum can clear lung heat.

7. A Chinese medicine composition for treating colds caused by wind pathogens according to claim 1, characterized in that: The scutellaria baicalensis is bitter in taste and cold in nature, and has the effects of clearing away heat and dampness, purging fire and detoxifying, stopping bleeding, and stabilizing the fetus; the white scutellaria baicalensis is bitter in taste and slightly cold in nature, and has the effects of clearing heat and detoxifying, diuresis, and removing rheumatism. Both can clear lung heat.

8. A Chinese medicine composition for treating colds caused by wind pathogens according to claim 1, characterized in that: The Aster is pungent in taste, bitter and warm in nature, and has the effects of resolving phlegm and relieving cough. Aster is pungent, dispersing, bitter and purging, has a stronger expectorant effect, but a weaker cough-relieving effect.

9. A Chinese medicine composition for treating colds caused by wind pathogens taken orally according to claim 1, characterized in that: The coltsfoot flower is pungent in taste and warm in nature, and has the effect of relieving cough and reducing phlegm. The coltsfoot flower and aster have similar effects, both of which can reduce phlegm and relieve cough, so they are often used together in clinical applications, but the coltsfoot flower has a stronger cough-relieving effect and a weaker expectorant effect; aster is just the opposite, and the two have a better expectorant and cough-relieving effect when used together.

10. A method for preparing a Chinese medicine composition for treating colds caused by wind pathogens according to claims 1-9, characterized in that: The following steps are involved: S1: Take 10g of Ephedra, 10g of Bitter Apricot, 10g of Belamcanda, 10g of Puffball, 10g of Fritillaria, 10g of Platycodon, 10g of Radix Phellodendri, 10g of Peucedanum, 20g of Scutellaria, 20g of Bletilla striata, 10g of Aster, and 10g of Coltsfoot. Soak the medicines in cold water for 30-60 minutes. The amount of water should be enough to cover the medicine surface by 3cm-5cm. S2: Put the medicine on the fire and boil it with high heat. After boiling, switch to low heat and keep it in a boiling state to slow down the evaporation of water, which is conducive to the dissolution of effective ingredients. Start timing after switching to low heat. Antipyretic drugs are also called drugs for treating colds. Boil for about 15-20 minutes, and other drugs are generally boiled for 40-50 minutes; S3: Pour out the first decoction, add appropriate amount of hot water (not too much water, just enough to cover the medicinal materials by 2cm-3cm), and perform the second decoction. The decoction time is about 20-30 minutes. Take it once in the morning and evening, and drink it hot half an hour after a meal.

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