Solid-liquid phase change microcapsule cooling cold cap for preventing alopecia in chemotherapy

By using a combination of solid-liquid phase change microcapsules and medical silicone layer in chemotherapy cold caps, the problem of hardening and scalp detachment after freezing of the cold caps is solved, and uniform cooling of the scalp and anti-hair loss effect is achieved.

CN120241359APending Publication Date: 2025-07-04UNIV OF SHANGHAI FOR SCI & TECH +1
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Patent Information

Application Number
CN202510229244.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-02-28
Publication Date
2025-07-04

AI Technical Summary

Technical Problem

The existing chemotherapy cold caps become hard after freezing and cannot fit tightly on the scalp, resulting in a gap between the scalp and the cold cap, affecting the anti-detachment effect of the head after chemotherapy.

Method used

Solid-liquid phase change microcapsules are used as cooling materials, and they are in solid powder form before and after freezing, with a certain deformation space. Combined with a medical silicone layer, it ensures that the cold cap is closely fitted with the scalp; at the same time, the thermally conductive bonding layer is equipped with protrusions or grooves to increase contact area and friction.

Benefits of technology

The cold cap is closely fitted with the scalp, avoiding gaps, ensuring uniform cooling of the scalp, and improving the anti-hair loss effect.

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Abstract

The invention provides a solid-liquid phase-change microcapsule cooling cold cap for preventing alopecia in chemotherapy. The solid-liquid phase-change microcapsule cooling cold cap comprises a shell layer, a phase-change cooling layer and a heat-conducting attaching layer, the phase change cooling layer is sealed between the heat conduction bonding layer and the shell layer; the phase change cooling layer comprises a frame and phase change microcapsules; the frame is built between the shell layer and the heat-conducting laminating layer, and the phase change microcapsules are filled between the shell layer and the heat-conducting laminating layer; the phase change microcapsule is a microcapsule encapsulated by a low-temperature solid-liquid phase change material; the solid-liquid phase change material is used as a cooling material, the cooling effect is remarkable, the solid-liquid phase change material is not particularly hard after being frozen, still has a certain deformation space and can be attached to all parts of the head of a patient, medical silica gel is used as the scalp attaching layer, the scalp attaching layer is soft, breathable and good in heat conduction and scalp attaching effect, and the cooling effect is good. The cold cap and the head of the patient are attached more tightly, and the phenomenon that a gap exists between the cold cap and the scalp, and the head anti-falling effect is affected after chemotherapy is avoided.
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Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to an anti - shedding cap for chemotherapy. Background Art

[0002] Chemotherapy - induced alopecia (CIA) is a well - known side effect of chemotherapy, and for more than half of patients, this is the most distressing aspect of the treatment process. Scalp cooling can prevent CIA through two mechanisms: First, during treatment, restrict blood flow to the hair follicles, thereby reducing the chance of contact with chemotherapy drugs; Second, slow down the metabolic rate of the hair follicles, thereby reducing the sensitivity of the hair follicles to the harmful effects of chemotherapy.

[0003] All techniques are mainly divided into two scalp cooling methods: cold caps (manual cooling systems, including Penguin cold caps, chemotherapy cold caps, and Arctic cold caps) and scalp cooling systems (automatic cooling systems). The machine - based automatic cooling system includes a tight cap connected to a coolant circulation device, which can gradually cool the scalp during treatment to maintain a set temperature. Manual techniques can use hand - held cold caps, which consist of a headgear similar to a shower cap and need to be frequently cooled during treatment to keep the scalp at a low temperature. However, this type of cold cap has portability / flexibility, does not restrict the patient's sitting position, is relatively affordable, and is relatively simple to operate. However, there are still some problems with this type of cold cap. For example, the existing cap becomes hard after freezing, does not fit closely to the scalp and has gaps, resulting in hair loss at the gap positions. Summary of the Invention

[0004] The purpose of the present invention is to propose a solid - liquid phase change material cooling cold cap that fully fits the human head and ensures uniform cooling of all parts of the patient's head.

[0005] To achieve the above - mentioned purpose, the present invention proposes a solid - liquid phase change micro - capsule cooling cold cap for preventing hair loss during chemotherapy, which includes a shell layer, a phase - change cooling layer, and a heat - conducting fitting layer; the phase - change cooling layer is sealed between the heat - conducting fitting layer and the shell layer;

[0006] The phase - change cooling layer includes a frame and phase - change micro - capsules; the frame is built between the shell layer and the heat - conducting fitting layer, and the phase - change micro - capsules are filled between the shell layer and the heat - conducting fitting layer;

[0007] The phase - change micro - capsules are micro - capsules encapsulated with low - temperature solid - liquid phase - change materials.

[0008] Furthermore, the shell is integrally injection - molded with plastic.

[0009] Furthermore, the low - temperature solid - liquid phase - change materials of the phase - change cooling layer include paraffin - based, fatty acid - based, polyol, or ester - based materials.

[0010] Furthermore, the shape of the frame is adapted to the shape of the human head.

[0011] Furthermore, the heat-conducting bonding layer is a medical-grade silicone layer, and the surface of the heat-conducting bonding layer is provided with protrusions or grooves for increasing the contact area and friction with the scalp.

[0012] Compared with the prior art, the advantages of the present invention are as follows: the present invention uses solid-liquid phase change microcapsules as the cooling material. By utilizing the characteristics that they are in the form of solid powder both before and after freezing, and they are not particularly hard after cooling and still have a certain deformation space, they can fit various parts of the patient's head; at the same time, medical silicone is used as the scalp attachment layer, which is soft, breathable, has good heat conduction and attachment effects, making the cold cap fit more closely with the patient's head, and avoiding gaps between the cold cap and the scalp, which may affect the anti-hair-loss effect after chemotherapy. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is an exploded view of the solid-liquid phase change material cooling cold cap in the embodiment of the present invention;

[0014] Figure 2 It is a linear graph of the scalp temperature change during cooling using paraffin phase change microcapsules in the embodiment of the present invention;

[0015] Figure 3 It is a numerical simulation temperature cloud map of the phase change process during cooling using paraffin phase change microcapsules in the embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0016] To make the objectives, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be further described below.

[0017] As Figure 1 shown, the present invention provides a solid-liquid phase change microcapsule cooling cold cap for preventing hair loss during chemotherapy, which is composed of three layers: an outer shell layer 1, a phase change cooling layer 2, and a heat-conducting bonding layer 3;

[0018] Specifically, the outer shell layer 1 is prepared by integrally injection molding with lightweight and strong plastic, and the outer surface is designed with anti-slip textures to improve the wearing stability.

[0019] The phase change cooling layer 2 consists of two parts: a frame and low-temperature solid-liquid phase change material capsules. The frame is prepared with a material having a certain deformation ability. In this embodiment, plastic is used to build a cooling cavity between the outer shell layer 1 and the heat-conducting bonding layer 3; (The frame provides effective support and guiding layout for the phase change material, avoiding local supercooling or local non-cooling conditions. At the same time, the flexible material can also be deformed and adjusted according to the user's head, providing better fit and comfort, and ensuring that the cooling effect is not affected.

[0020] In this embodiment, the low-temperature solid-liquid phase change material capsules are prepared by encapsulating paraffin into microcapsules; then they are filled into the cooling cavity. The paraffin microcapsules are first cooled by freezing. After cooling, the internal material of the paraffin microcapsules undergoes a phase change, and the outer shell remains in a solid form. The phase change cooling layer 2 is in a powder state and is not too hard, so it can adapt to the deformation of the scalp surface and can better fit the scalp for cooling. In the actual application process, the paraffin itself absorbs heat and changes from a solid state to a liquid state, so as to continuously absorb heat and cool the scalp while ensuring the degree of fit with the scalp. At the same time, the size of the microcapsules is selected between microns and millimeters. The smaller microcapsules can provide a larger specific surface area, which is beneficial to heat transfer and storage. As Figure 2 shown, during the cooling process of the paraffin, the scalp surface can maintain a low-temperature state for at least 80 minutes, and the effect is remarkable; Based on Figure 3 it can be understood that: the phase change microcapsules absorb heat in the phase change temperature range, preferably maintaining the temperature stability inside the cold cap, ensuring uniform distribution of heat on the head, and avoiding local overheating or overcooling.

[0021] The heat-conducting and fitting layer 3 is a medical-grade silicone layer. The silicone layer has a remarkable heat-conducting effect, which can ensure heat absorption and cooling of the scalp. At the same time, the adhesion effect between the silicone and the scalp is better. In this embodiment, the surface of the heat-conducting and fitting layer 3 is provided with protrusions or grooves for increasing the contact area and friction with the scalp.

[0022] The above is only the preferred embodiment of the present invention and does not impose any limitation on the present invention. Any person skilled in the art, without departing from the technical solution of the present invention, makes any form of equivalent substitution or modification and other changes to the technical solution and technical content disclosed by the present invention, all of which belong to the content of the technical solution of the present invention and are still within the protection scope of the present invention.

Claims

1. A solid-liquid phase change microcapsule cooling cold cap for preventing hair loss during chemotherapy, characterized in that, It includes a shell layer, a phase change cooling layer and a heat conduction bonding layer; the phase change cooling layer is sealed between the heat conduction bonding layer and the shell layer; The phase change cooling layer includes a frame and phase change microcapsules; the frame is built between the shell layer and the heat conduction bonding layer, and the phase change microcapsules are filled between the shell layer and the heat conduction bonding layer; the phase change microcapsules are microcapsules encapsulated with a low-temperature solid-liquid phase change material.

2. The solid-liquid phase change microcapsule cooling cap for preventing hair loss during chemotherapy according to claim 1, wherein The shell is integrally injection-molded with plastic.

3. The solid-liquid phase change microcapsule cooling cap for preventing hair loss during chemotherapy according to claim 1, characterized in that, The low-temperature solid-liquid phase change material of the phase change cooling layer includes paraffin, fatty acids, polyols or ester materials.

4. The solid-liquid phase change microcapsule cooling cap for preventing hair loss during chemotherapy according to claim 1, characterized in that The shape of the frame fits the shape of the human head.

5. The solid-liquid phase change microcapsule cooling cap for preventing hair loss during chemotherapy according to claim 1, characterized in that, The heat conduction bonding layer is a medical-grade silicone layer, and the surface of the heat conduction bonding layer is provided with protrusions or grooves for increasing the contact area and friction with the scalp.

Citation Information

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