Concentration device for preparing deferasirox raw material

Abstract

The invention relates to the technical field of concentration, in particular to a concentration device for preparing deferasirox raw materials, which comprises a box body and the like, a liquid storage area and a concentration area are vertically arranged in the box body, the liquid storage area is communicated with the concentration area through at least one pipeline, at least one liquid inlet is arranged on the pipeline, and a vacuum pump is communicated with the outer side wall of the concentration area. A second temperature control rod is arranged in the concentration area, at least one concentration barrel is mounted in the concentration area, and the concentration barrel is communicated with the pipeline. The device is provided with the box body, the concentration cylinders, the first spiral blades and other parts, the boiling point of a solution is reduced through a vacuum environment, the multiple concentration cylinders are arranged for high-temperature concentration, the original same amount of solution is divided into multiple groups for high-temperature concentration, the high-temperature concentration time is shortened, and part of active ingredients are prevented from being damaged by heating; then low-temperature concentration is conducted in the final stage of concentration, it is ensured that thermosensitive components in the solution are kept stable by further lowering the temperature, and finally the high-concentration deferasirox raw material solution is obtained.

Description

Technical Field

[0001] The present invention relates to the technical field of concentration, and particularly to a concentration device for preparing deferasirox raw materials. Background Art

[0002] Deferasirox is the first conventional oral iron chelator approved by the US FDA, and is particularly suitable for patients aged 2 and above with chronic iron overload caused by blood transfusion. In Europe, deferasirox is listed as a first-line treatment drug for thalassemia iron overload patients aged 6 and above. During the synthesis of deferasirox, the concentration of certain intermediates or reaction solutions in the solution is relatively low, and it may be necessary to concentrate them by methods such as solvent evaporation to improve the reaction efficiency and ensure the smooth progress of subsequent reactions.

[0003] Existing concentration devices, such as the patent with the authorization announcement number CN222195920U, disclose a concentration device for pharmaceutical production. Although it can scrape off the drugs remaining at the bottom of the inner wall to avoid residues, the solution may be heated at a high temperature for a long time, which is likely to cause overheating of the material, and then the chemical stability of deferasirox may be affected by the high temperature, resulting in product degradation. In view of this, the present invention provides a concentration device for preparing deferasirox raw materials to solve the above-mentioned technical problems. Summary of the Invention

[0004] In order to overcome the technical problems mentioned in the background art, the present invention provides a concentration device for preparing deferasirox raw materials.

[0005] The technical solution is as follows: A concentration device for preparing deferasirox raw materials includes a box body, in which a liquid storage area and a concentration area are arranged up and down. The liquid storage area and the concentration area are connected by at least one pipeline, and at least one liquid inlet is arranged on the pipeline. A lifting plate is slidably connected in a sealed manner in the liquid storage area, and the lifting plate is driven by a first driving component to slide up and down. A vacuum pump is connected to the outer side wall of the concentration area, and a second temperature control rod is arranged in the concentration area; A concentration cylinder, at least one concentration cylinder is installed in the concentration area, and the concentration cylinder is connected to the pipeline. The concentration cylinder includes a cylinder cover fixedly connected to the top surface of the concentration area. The bottom surface of the cylinder cover is rotatably connected to a rotating cylinder, and the rotating cylinder is driven to rotate by a second driving component. A bottom cover is arranged at the lower end of the rotating cylinder, and the bottom cover is driven by a third driving component to seal or unseal the rotating cylinder. A stirring component and a heating cavity are arranged in the rotating cylinder, and a first temperature control rod is arranged in the heating cavity. The temperature of the first temperature control rod is higher than that of the second temperature control rod; A filtering component, which is installed in the concentration area and is located directly below the concentration cylinder.

[0006] As a further preferred solution, the liquid storage area is separated into a first liquid inlet area and a second liquid inlet area by a partition board. A first liquid inlet pipe and a second liquid inlet pipe are respectively arranged on the side walls of the first liquid inlet area and the second liquid inlet area. Valves are installed on both the first liquid inlet pipe and the second liquid inlet pipe. Lifting plates are hermetically and slidably connected in both the first liquid inlet area and the second liquid inlet area, and the lifting plates are respectively driven by corresponding first driving components to slide up and down. Two liquid inlet ports are symmetrically arranged on the pipeline, and the two liquid inlet ports are respectively located in the first liquid inlet area and the second liquid inlet area. A first spiral blade is fixedly connected to the lower end inside the pipeline.

[0007] As a further preferred solution, the stirring component includes a fixed rod fixedly connected to the middle of the bottom surface of the cylinder cover. The pipeline penetrates through the cylinder cover and extends into the rotating cylinder. A gap is provided between the fixed rod and the lower end of the rotating cylinder. Second helical gears are evenly distributed on the fixed rod. First rotating rods are evenly distributed and rotatably connected in the rotating cylinder. Stirring rods are fixedly connected to the first rotating rods. A first helical gear is fixedly connected to one end of the first rotating rod close to the second helical gear. The first helical gear meshes with the second helical gear.

[0008] As a further preferred solution, at least two pipelines are connected and communicated between the liquid storage area and the concentration area. At least two concentration cylinders are installed in the concentration area. The second driving component includes a second driving motor installed on the outer side wall of the concentration area. A fourth helical gear is fixedly connected to the output shaft of the second driving motor. A third helical gear meshing with the fourth helical gear is installed on one of the rotating cylinders. Driving gears are installed on the rotating cylinders. Adjacent driving gears mesh with each other.

[0009] As a further preferred solution, the third driving component includes a first driving motor installed on the outer side wall of the concentration area. A second rotating rod is rotatably connected in the concentration area. The second rotating rod is fixedly connected to the bottom cover.

[0010] As a further preferred solution, the filtering component includes a drawer box slidably connected in the concentration area. The drawer box is located directly below the concentration cylinder. A filter plate is slidably connected to the drawer box. An elastic member is arranged between the filter plate and the drawer box. At least one extrusion rod is fixedly connected to the bottom cover. A special-shaped plate cooperating with the extrusion rod is installed on the top surface of the filter plate. The special-shaped plate presents a "concave" shape.

[0011] As a further preferred solution, a mounting plate is fixedly connected in the concentration area. The front and rear sides of the mounting plate are inclined planes, and the middle part is arc-shaped. A driving rod is rotatably connected at the arc-shaped part of the mounting plate in the concentration area. A second spiral blade is fixedly connected to the side wall of the driving rod. The driving rod is connected to the output shaft of the second driving motor through a synchronous belt component. Second temperature control rods are installed between the front and rear sides of the mounting plate and the inner wall of the concentration area. A liquid outlet is arranged on one side of the concentration area far from the synchronous belt component.

[0012] As a further preferred solution, it further includes a gas treatment component. At least two groups of gas treatment components are installed on the top surface of the box body. One of the gas treatment components is communicated with a vacuum pump, and the remaining gas treatment components are communicated with pipelines. The gas treatment component includes a sealing cylinder fixedly connected to the top surface of the box body. An air outlet and a first air inlet are respectively arranged at the upper and lower ends of the sealing cylinder. A valve body is installed on the air outlet, and the first air inlet is communicated with the corresponding pipeline or vacuum pump. A treatment box is slidably connected in the sealing cylinder. A semi-circular limiting protrusion is arranged on the upper part of the treatment box. An activated carbon plate is slidably connected between the limiting protrusion and the treatment box. A second air inlet is arranged at the bottom of the treatment box, and the second air inlet is communicated with the first air inlet. A third rotating rod is rotatably connected in the second air inlet. A rotating fan blade is fixedly connected to the bottom of the third rotating rod. A scraping rod is fixedly connected to the top of the third rotating rod, and the scraping rod is in contact with the bottom of the activated carbon plate. A one-way valve is installed at the liquid inlet.

[0013] As a further preferred solution, both the fixed rod and the driving rod are hollow, and a first temperature control rod and a second temperature control rod are respectively installed in the fixed rod and the driving rod.

[0014] As a further preferred solution, an operation screen is also installed on the outer side wall of the box body, and the operation screen is electrically connected to all electrical components.

[0015] The present invention has the following advantages: The present invention is provided with components such as a box body, a concentration cylinder, and a first spiral blade. By creating a vacuum environment, the boiling point of the solution is reduced. Multiple concentration cylinders are set for high-temperature concentration. The originally equal amount of solution is divided into multiple groups for high-temperature concentration, shortening the time of high-temperature concentration and avoiding the destruction of some active ingredients by heat. Then, in the final stage of concentration, it is transferred to low-temperature concentration to ensure the stability of the thermosensitive components in the solution by further reducing the temperature, and at the same time further concentrate the solution to finally obtain a high-concentration deferasirox raw material solution. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic structural diagram of the present invention.

[0017] Figure 2 It is another schematic structural diagram of the present invention.

[0018] Figure 3 It is a cross-sectional view of the present invention.

[0019] Figure 4 It is a cross-sectional view of components such as the box body, partition board, and lifting plate of the present invention.

[0020] Figure 5 It is a cross-sectional view of the pipeline and the first spiral blade of the present invention.

[0021] Figure 6 It is a cross-sectional view of components such as the concentration cylinder of the present invention.

[0022] Figure 7 A cross-sectional view of components such as the stirring assembly of the present invention.

[0023] Figure 8 A schematic diagram of components such as the concentration cylinder, filtration assembly, and mounting plate of the present invention.

[0024] Figure 9 Another schematic diagram of components such as the concentration cylinder, filtration assembly, and mounting plate of the present invention.

[0025] Figure 10 The first state diagram of the bottom cover, extrusion rod, and special-shaped plate of the present invention.

[0026] Figure 11 The second state diagram of the bottom cover, extrusion rod, and special-shaped plate of the present invention.

[0027] Figure 12 A cross-sectional view of the gas treatment assembly of the present invention.

[0028] Figure 13 A schematic diagram of components such as the activated carbon plate, scraping rod, and treatment box of the present invention after disassembly.

[0029] Wherein: 1 - box body, 11 - liquid storage area, 111 - first liquid inlet area, 112 - second liquid inlet area, 12 - concentration area, 13 - first liquid inlet pipe, 14 - second liquid inlet pipe, 15 - liquid outlet, 21 - pipeline, 211 - liquid inlet, 22 - lifting plate, 23 - vacuum pump, 24 - second temperature control rod, 25 - concentration cylinder, 251 - cylinder cover, 252 - rotating cylinder, 2521 - heating cavity, 253 - bottom cover, 26 - first temperature control rod, 27 - first spiral blade, 28 - partition plate, 31 - fixing rod, 32 - second helical gear, 33 - first rotating rod, 34 - stirring rod, 35 - first helical gear, 41 - second driving motor, 42 - fourth helical gear, 43 - third helical gear, 44 - driving gear, 51 - first driving motor, 52 - second rotating rod, 61 - drawer box, 62 - filter plate, 63 - elastic member, 64 - extrusion rod, 65 - special-shaped plate, 71 - mounting plate, 72 - driving rod, 73 - second spiral blade, 74 - synchronous belt component, 81 - sealing cylinder, 811 - first air inlet, 812 - air outlet, 82 - treatment box, 821 - limiting projection, 822 - second air inlet, 83 - activated carbon plate, 84 - third rotating rod, 85 - rotating fan blade, 86 - scraping rod, 91 - operation screen, 92 - electric push rod. Detailed implementation manners

[0030] The present invention will be further described below in conjunction with specific embodiments. It should also be noted that, unless otherwise clearly specified and defined, terms such as: setting, installation, connection, and coupling should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0031] A concentration device for preparing deferasirox raw materials, as Figures 1-13 shown, includes a box body 1. Inside the box body 1, a liquid storage area 11 and a concentration area 12 are arranged up and down. The liquid storage area 11 is separated into a first liquid inlet area 111 and a second liquid inlet area 112 by a partition 28. A first liquid inlet pipe 13 and a second liquid inlet pipe 14 are respectively arranged on the side walls of the first liquid inlet area 111 and the second liquid inlet area 112. Valves are installed on both the first liquid inlet pipe 13 and the second liquid inlet pipe 14. The valve is specifically a solenoid valve, which is used to open or close the channels of the first liquid inlet pipe 13 and the second liquid inlet pipe 14. Among them, the first liquid inlet area 111 is filled with a deferasirox raw material solution, and the second liquid inlet area 112 is filled with auxiliary materials (such as a pH regulator) to help optimize the concentration process, thereby improving the quality of the product. A lifting plate 22 is hermetically and slidably connected in both the first liquid inlet area 111 and the second liquid inlet area 112, and the lifting plate 22 is driven by a corresponding first driving component to slide up and down. The first driving component is specifically an electric push rod 92 installed on the top surface of the box body 1. The telescopic rod of the electric push rod 92 is fixedly connected to the corresponding lifting plate 22. In other embodiments, a hoisting device can be used to achieve the same effect. The liquid storage area 11 and the concentration area 12 are connected by five pipes 21. The five pipes 21 are evenly distributed. Two liquid inlet ports 211 are symmetrically arranged on the pipe 21, and the two liquid inlet ports 211 are respectively located in the first liquid inlet area 111 and the second liquid inlet area 112. The liquid levels in the first liquid inlet area 111 and the second liquid inlet area 112 are lower than the liquid inlet ports 211. A first spiral blade 27 is fixedly connected to the lower end inside the pipe 21. Thus, when the solutions in the first liquid inlet area 111 and the second liquid inlet area 112 flow from the liquid storage area 11 to the concentration area 12, the first spiral blade 27 can stir and mix the two solutions, enabling them to come into contact more fully, helping the auxiliary materials to play a better role, optimizing the concentration process, and further improving the product quality; A vacuum pump 23 is connected to the outer wall of the concentration area 12. A second temperature control rod 24 is arranged in the concentration area 12. Five concentration cylinders 25 are installed in the concentration area 12. The concentration cylinders 25 are communicated with the corresponding pipelines 21. The concentration cylinder 25 includes a cylinder cover 251 fixedly connected to the top surface of the concentration area 12. A rotary cylinder 252 is rotatably connected to the bottom surface of the cylinder cover 251. The rotary cylinder 252 is driven to rotate by a second driving assembly. A bottom cover 253 is arranged at the lower end of the rotary cylinder 252. The bottom cover 253 is driven by a third driving assembly to seal or unseal the rotary cylinder 252. A stirring assembly and a heating cavity 2521 are arranged in the rotary cylinder 252. A first temperature control rod 26 is arranged in the heating cavity 2521. The first temperature control rod 26 is installed on the bottom surface of the cylinder cover 251. The temperature of the first temperature control rod 26 is higher than that of the second temperature control rod 24. A filtering assembly is installed in the concentration area 12 and is located directly below the concentration cylinder 25; It can be seen from this that when concentration is required, first close the valve bodies on the first liquid inlet pipe 13 and the second liquid inlet pipe 14, then start the third driving assembly so that the bottom cover 253 is not sealed with the rotating cylinder 252, thereby connecting the liquid storage area 11 and the concentration area 12. Then use the vacuum pump 23 to evacuate the inside of the box body 1 to a vacuum, reducing the pressure inside the box body 1. Then start the third driving assembly so that the bottom cover 253 is sealed with the rotating cylinder 252, and the liquid storage area 11 and the concentration area 12 are not connected. Open the valve bodies on the first liquid inlet pipe 13 and the second liquid inlet pipe 14, and inject the deferasirox raw material solution and the auxiliary material solution into the first liquid inlet area 111 and the second liquid inlet area 112 respectively through the first liquid inlet pipe 13 and the second liquid inlet pipe 14. The liquid levels of the two solutions are lower than the liquid inlet 211. After the liquid surfaces are calm, start the first driving assembly, that is, start the electric push rod 92. The telescopic rod of the electric push rod 92 retracts, causing the lifting plate 22 to move upward, thereby lifting the solutions in the first liquid inlet area 111 and the second liquid inlet area 112, making the liquid levels higher than the liquid inlet 211, and thus the solutions will flow into the pipe 21. By controlling the height and rate of the lifting plate 22 lifted by the electric push rod 92, the speed and flow rate of the solutions entering the pipe 21 can be controlled, enabling the raw materials and auxiliary materials to achieve the best ratio, ensuring the activity and stability of the final product. After the two solutions enter the pipe 21, they freely flow downward under the influence of gravity, and during the flowing process, the first spiral blade 27 stirs and mixes the two solutions, making them contact more fully, which helps the auxiliary materials play a better role. Finally, the two solutions merge into a new solution and fall into the concentration cylinder 25. Then start the first temperature control rod 26 for high-temperature heating, and thus the new solution is concentrated at a high temperature in the rotating cylinder 252. During high-temperature concentration, due to the relatively vacuum environment, the boiling point of the solution is reduced. The first temperature control rod 26 will strictly control the temperature to reach an appropriate range and not be too high. At the same time, the time of high-temperature concentration is controlled to be relatively short, so as to avoid the degradation of some heat-sensitive components (such as some active pharmaceutical ingredients). In this way, during high-temperature concentration, some volatile substances will be removed first, reducing the volume of the solution, and thus some solid impurities will be precipitated. Then start the third driving assembly so that the bottom cover 253 is not sealed with the rotating cylinder 252, and the solution in the concentration cylinder 25 falls into the concentration area 12. The precipitated solid impurities will be filtered out by the filter assembly, while the solution falls to the bottom of the concentration area 12. Start the second temperature control rod 24 to heat the solution at a low temperature, so that the solution is concentrated at a low temperature in the concentration area 12, further improving the concentration effect, and finally obtaining a high-concentration deferasirox raw material solution. In this way, the boiling point of the solution is reduced through a vacuum environment, multiple concentration cylinders 25 are set for high-temperature concentration, the originally equal amount of solution is divided into multiple groups for high-temperature concentration, shortening the time of high-temperature concentration, avoiding the destruction of some active components by heat, and then transferring to low-temperature concentration in the final stage of concentration, and further reducing the temperature to ensure the stability of the heat-sensitive components in the solution.Meanwhile, the solution is further concentrated to finally obtain a high-concentration deferasirox raw material solution.

[0032] Furthermore, in order to make the effect of high-temperature concentration better, the stirring assembly includes a fixed rod 31 fixedly connected to the middle of the bottom surface of the cylinder cover 251. The pipeline 21 penetrates through the cylinder cover 251 and extends into the rotating cylinder 252. The fixed rod 31 is arranged with a gap from the lower end of the rotating cylinder 252. Second helical gears 32 are evenly distributed on the fixed rod 31. First rotating rods 33 are evenly distributed and rotatably connected in the rotating cylinder 252. Stirring rods 34 are fixedly connected to the first rotating rods 33. A first helical gear 35 is fixedly connected to one end of the first rotating rod 33 close to the second helical gear 32. The first helical gear 35 meshes with the second helical gear 32. The second driving assembly includes a second driving motor 41 installed on the outer side wall of the concentration area 12. A fourth helical gear 42 is fixedly connected to the output shaft of the second driving motor 41. A third helical gear 43 meshing with the fourth helical gear 42 is installed on one of the rotating cylinders 252. A driving gear 44 is installed on the rotating cylinder 252. Adjacent driving gears 44 mesh with each other. It can be seen that when the second driving motor 41 is started, the output shaft of the second driving motor 41 drives the fourth helical gear 42 to rotate. The fourth helical gear 42 drives the third helical gear 43 to rotate through meshing transmission, and then drives the rotating cylinder 252 to rotate. The rotation of the rotating cylinder 252 drives the first rotating rod 33 to rotate around the fixed rod 31. Furthermore, the first helical gear 35 rotates around the second helical gear 32. Since the first helical gear 35 meshes with the second helical gear 32, the first helical gear 35 rotates self. The self-rotation of the first helical gear 35 drives the first rotating rod 33 to rotate self. Furthermore, the first rotating rod 33 drives the stirring rod 34 to rotate. In this way, while the first rotating rod 33 keeps stirring the solution in the horizontal direction, a vortex is formed in the vertical direction by the stirring rod 34 to provide two-way stirring, break the layers of the solution, and enable the bottom solution to exchange with the upper solution. In this way, not only the uniformity of the solution is improved, but also the contact area between the solution and the heat source is increased, thereby accelerating heat transfer and enhancing the efficiency of the high-temperature concentration process. At the same time, it can ensure that the substances in the rotating cylinder 252 are fully mixed, effectively avoiding the formation of dead zones or non-stirred areas in the solution and avoiding the unevenness of the concentration process.

[0033] The third driving assembly includes a first driving motor 51 installed on the outer side wall of the concentration area 12. A second rotating rod 52 is rotatably connected in the concentration area 12. The second rotating rod 52 is fixedly connected to the bottom cover 253. It can be seen that when the first driving motor 51 is started, the output shaft of the first driving motor 51 drives the second rotating rod 52 to rotate. Furthermore, the second rotating rod 52 drives the bottom cover 253 to rotate, so that the bottom cover 253 can be sealed or unsealed with the rotating cylinder 252.

[0034] Furthermore, in order to remove solid impurities in the liquid after high-temperature concentration, the filtration assembly includes a drawer box 61 slidably connected in the concentration area 12. The drawer box 61 is located directly below the concentration cylinder 25. A filter plate 62 is slidably connected to the drawer box 61. An elastic member 63 is arranged between the filter plate 62 and the drawer box 61. The elastic member 63 is specifically a spring. Extrusion rods 64 are fixedly connected to the bottom covers 253 on both the left and right sides. A special-shaped plate 65 that cooperates with the extrusion rods 64 is installed on the top surface of the filter plate 62. The special-shaped plate 65 presents a "concave" shape. It can be seen from this that when the bottom cover 253 is opened, the extrusion rods 64 on the bottom cover 253 will squeeze the special-shaped plate 65, and then the special-shaped plate 65 drives the filter plate 62 to slide up and down. As Figure 10 shown, the filter plate 62 then squeezes the elastic member 63, causing the elastic member 63 to store elastic potential energy. Since the special-shaped plate 65 presents a "concave" shape, when the extrusion rod 64 moves to the middle of the special-shaped plate 65, the elastic member 63 releases the elastic potential energy, driving the filter plate 62 to reset. In this way, the filter plate 62 can vibrate once. As the extrusion rod 64 continues to rotate, the extrusion rod 64 will squeeze the special-shaped plate 65 again, and the filter plate 62 will vibrate again. This can prevent solid impurities from blocking the filter plate 62 and prevent the accumulation of solid impurities.

[0035] Furthermore, a mounting plate 71 is fixedly connected in the concentration area 12. The front and rear sides of the mounting plate 71 are inclined planes, and the middle part is arc-shaped. A driving rod 72 is rotatably connected at the arc-shaped part of the mounting plate 71 in the concentration area 12. A second spiral blade 73 is fixedly connected to the side wall of the driving rod 72. The driving rod 72 is connected to the output shaft of the second driving motor 41 through a synchronous belt component 74. Second temperature control rods 24 are installed between the front and rear sides of the mounting plate 71 and the inner wall of the concentration area 12. An outlet 15 is arranged on one side of the concentration area 12 away from the synchronous belt component 74. It can be seen from this that when the solution falls into the concentration area 12, it will directly fall into the arc-shaped area of the mounting plate 71. When the output shaft of the second driving motor 41 rotates, the driving rod 72 is driven to rotate through the synchronous belt component 74. Then the driving rod 72 drives the second spiral blade 73 to rotate, so that the solution is continuously stirred and conveyed to the outlet 15. At the same time, the second temperature control rods 24 are started, and the second temperature control rods 24 perform low-temperature concentration on the solution.

[0036] Further, in order to process the concentrated gas, a gas processing component is further included. Six groups of gas processing components are installed on the top surface of the box body 1. One of the gas processing components is communicated with the vacuum pump 23, and the remaining gas processing components are communicated with the pipeline 21. The gas processing component includes a sealing cylinder 81 fixedly connected to the top surface of the box body 1. An air outlet 812 and a first air inlet 811 are respectively arranged at the upper and lower ends of the sealing cylinder 81. A valve body is installed on the air outlet 812, and the first air inlet 811 is communicated with the corresponding pipeline 21 or the vacuum pump 23. A processing box 82 is slidably connected in the sealing cylinder 81. A semi-circular limiting protrusion 821 is arranged on the upper part of the processing box 82. An activated carbon plate 83 is slidably connected between the limiting protrusion 821 and the processing box 82. A second air inlet 822 is arranged at the bottom of the processing box 82, and the second air inlet 822 is communicated with the first air inlet 811. A third rotating rod 84 is rotatably connected in the second air inlet 822. A rotating fan blade 85 is fixedly connected to the bottom of the third rotating rod 84. A scraping rod 86 is fixedly connected to the top of the third rotating rod 84, and the scraping rod 86 is in contact with the bottom of the activated carbon plate 83. A one-way valve is installed at the liquid inlet 211. It can be seen that the concentrated gas enters the sealing cylinder 81 from the first air inlet 811 and the second air inlet 822. The activated carbon plate 83 will adsorb the concentrated gas, and then the filtered gas flows into the outside through the air outlet 812. When the gas flows, it will drive the rotating fan blade 85 to rotate. Then the rotating fan blade 85 drives the third rotating rod 84 to rotate. Then the third rotating rod 84 drives the scraping rod 86 to rotate. The scraping rod 86 can clean the bottom surface of the activated carbon plate 83 to prevent the adsorbed substances from blocking the holes on the activated carbon plate 83. The setting of the limiting protrusion 821 can prevent the gas from blowing the activated carbon plate 83 and causing the activated carbon plate 83 to shake up and down, and at the same time make it more convenient to replace the activated carbon plate 83.

[0037] Further, the fixing rod 31 and the driving rod 72 are both hollow. A first temperature control rod 26 and a second temperature control rod 24 are respectively installed in the fixing rod 31 and the driving rod 72, so that the concentration effect is better.

[0038] Further, an operation screen 91 is also installed on the outer side wall of the box body 1. The operation screen 91 is electrically connected to all electrical components, so that it is convenient for the staff to operate.

[0039] The above is only the specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art can easily think of changes or substitutions within the technical scope disclosed by the present invention, and all should be covered by the protection scope of the present invention. Therefore, the protection scope of the present invention should be subject to the protection scope of the claims.

Claims

1. A concentration device for preparing deferasirox raw materials, characterized in that: It includes a box body (1). Inside the box body (1), a liquid storage area (11) and a concentration area (12) are arranged vertically. The liquid storage area (11) and the concentration area (12) are connected and communicated through at least one pipeline (21). At least one liquid inlet (211) is arranged on the pipeline (21). A lifting plate (22) is slidably connected in a sealed manner in the liquid storage area (11). The lifting plate (22) is driven by a first driving component to slide up and down. A vacuum pump (23) is communicated with the outer side wall of the concentration area (12). A second temperature control rod (24) is arranged in the concentration area (12). A concentration cylinder (25). At least one concentration cylinder (25) is installed in the concentration area (12). The concentration cylinder (25) is connected and communicated with the pipeline (21). The concentration cylinder (25) includes a cylinder cover (251) fixedly connected to the top surface of the concentration area (12). A rotating cylinder (252) is rotatably connected to the bottom surface of the cylinder cover (251). The rotating cylinder (252) is driven to rotate by a second driving component. A bottom cover (253) is arranged at the lower end of the rotating cylinder (252). The bottom cover (253) is driven by a third driving component to seal or unseal the rotating cylinder (252). A stirring component and a heating cavity (2521) are arranged in the rotating cylinder (252). A first temperature control rod (26) is arranged in the heating cavity (2521). The temperature of the first temperature control rod (26) is higher than that of the second temperature control rod (24). A filtering component. The filtering component is installed in the concentration area (12) and is located directly below the concentration cylinder (25).

2. The concentration device for preparing deferasirox raw materials according to claim 1, characterized in that: The liquid storage area (11) is separated into a first liquid inlet area (111) and a second liquid inlet area (112) by a partition plate (28). A first liquid inlet pipe (13) and a second liquid inlet pipe (14) are respectively arranged on the side walls of the first liquid inlet area (111) and the second liquid inlet area (112). Valves are installed on both the first liquid inlet pipe (13) and the second liquid inlet pipe (14). Lifting plates (22) are slidably connected in a sealed manner in both the first liquid inlet area (111) and the second liquid inlet area (112). And the lifting plates (22) are both driven by corresponding first driving components to slide up and down. Two liquid inlets (211) are symmetrically arranged on the pipeline (21). And the two liquid inlets (211) are respectively located in the first liquid inlet area (111) and the second liquid inlet area (112). A first spiral blade (27) is fixedly connected to the lower end inside the pipeline (21).

3. The concentration device for preparing deferasirox raw materials according to claim 2, wherein: The stirring component includes a fixed rod (31) fixedly connected to the middle of the bottom surface of the cylinder cover (251). The pipeline (21) penetrates through the cylinder cover (251) and extends into the inside of the rotating cylinder (252). A gap is provided between the fixed rod (31) and the lower end of the rotating cylinder (252). Second helical gears (32) are evenly distributed on the fixed rod (31). First rotating rods (33) are evenly distributed and rotatably connected in the rotating cylinder (252). Stirring rods (34) are fixedly connected to the first rotating rods (33). A first helical gear (35) is fixedly connected to one end of the first rotating rod (33) close to the second helical gear (32). The first helical gear (35) meshes with the second helical gear (32).

4. The concentration device for preparing deferasirox raw materials according to claim 3, characterized in that: The liquid storage area (11) and the concentration area (12) are connected through at least two pipes (21). At least two concentration cylinders (25) are installed in the concentration area (12). The second driving assembly includes a second driving motor (41) installed on the outer side wall of the concentration area (12). A fourth helical gear (42) is fixedly connected to the output shaft of the second driving motor (41). A third helical gear (43) meshing with the fourth helical gear (42) is installed on one of the rotating cylinders (252). A driving gear (44) is installed on the rotating cylinder (252), and two adjacent driving gears (44) mesh with each other.

5. A concentration device for preparing deferasirox raw materials according to claim 4, characterized in that: The third driving assembly includes a first driving motor (51) installed on the outer side wall of the concentration area (12). A second rotating rod (52) is rotatably connected in the concentration area (12), and the second rotating rod (52) is fixedly connected to the bottom cover (253).

6. The concentration device for preparing deferasirox raw materials according to claim 5, characterized in that: The filtering assembly includes a drawer box (61) slidably connected in the concentration area (12). The drawer box (61) is located directly below the concentration cylinder (25). A filter plate (62) is slidably connected to the drawer box (61). An elastic member (63) is arranged between the filter plate (62) and the drawer box (61). An extrusion rod (64) is fixedly connected to at least one bottom cover (253). A special-shaped plate (65) cooperating with the extrusion rod (64) is installed on the top surface of the filter plate (62), and the special-shaped plate (65) is in a "concave" shape.

7. The concentrating device for preparing deferasirox raw materials according to claim 6, characterized in that: A mounting plate (71) is fixedly connected in the concentration area (12). The front and rear sides of the mounting plate (71) are inclined planes, and the middle part is arc-shaped. A driving rod (72) is rotatably connected in the concentration area (12) at the arc-shaped part of the mounting plate (71). A second helical blade (73) is fixedly connected to the side wall of the driving rod (72). The driving rod (72) is connected to the output shaft of the second driving motor (41) through a synchronous belt component (74). Second temperature control rods (24) are installed between the front and rear sides of the mounting plate (71) and the inner wall of the concentration area (12). An outlet (15) is arranged on one side of the concentration area (12) far from the synchronous belt component (74).

8. A concentration device for preparing deferasirox raw materials according to claim 7, characterized in that: It further includes a gas treatment component. At least two groups of gas treatment components are installed on the top surface of the box body (1). One of the gas treatment components is communicated with a vacuum pump (23), and the remaining gas treatment components are communicated with a pipeline (21). The gas treatment component includes a sealing cylinder (81) fixedly connected to the top surface of the box body (1). An air outlet (812) and a first air inlet (811) are respectively arranged at the upper and lower ends of the sealing cylinder (81). A valve body is installed on the air outlet (812). The first air inlet (811) is communicated with the corresponding pipeline (21) or the vacuum pump (23). A treatment box (82) is slidably connected in the sealing cylinder (81). A semi-circular limiting protrusion (821) is arranged on the upper part of the treatment box (82). An activated carbon plate (83) is slidably connected between the limiting protrusion (821) and the treatment box (82). A second air inlet (822) is arranged at the bottom of the treatment box (82). The second air inlet (822) is communicated with the first air inlet (811). A third rotating rod (84) is rotatably connected in the second air inlet (822). A rotating fan blade (85) is fixedly connected to the bottom of the third rotating rod (84). A scraping rod (86) is fixedly connected to the top of the third rotating rod (84). The scraping rod (86) is in contact with the bottom of the activated carbon plate (83). A one-way valve is installed at the liquid inlet (211).

9. The concentration device for preparing deferasirox raw materials according to claim 8, characterized in that: The fixed rod (31) and the driving rod (72) are both hollow. A first temperature control rod (26) and a second temperature control rod (24) are respectively installed in the fixed rod (31) and the driving rod (72).

10. A concentration device for preparing deferasirox raw materials according to claim 9, characterized in that: An operation screen (91) is further installed on the outer side wall of the box body (1). The operation screen (91) is electrically connected to all electrical components.

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