Traditional Chinese medicine composition product for treating insomnia symptoms

Abstract

The invention provides a traditional Chinese medicine composition product for treating insomnia symptoms, and relates to the technical field of traditional Chinese medicines, and the traditional Chinese medicine composition product comprises cortex phellodendri, crude dragon bone, raw oyster, raw malt, rhizoma nardostachyos, patrinia and liquorice. The traditional Chinese medicine formula comprises the following components in parts by weight: 9-12 g of cortex phellodendri, 18-20 g of raw dragon bone, 18-20 g of raw oyster shell, 9-12 g of raw malt, 20-30 g of rhizoma nardostachyos, 13-15 g of herba patriniae and 3-5 g of liquorice. The traditional Chinese medicine composition has the advantages that multiple components in a prescription can regulate synthesis, release and uptake of neurotransmitters such as 5-hydroxytryptamine, gamma-aminobutyric acid and dopamine of the brain and maintain neurotransmitter balance, so that sleep is improved; the prescription can regulate the function of an HPA axis, reduce the secretion level of cortisol and other stress hormones in a stress state, relieve the stress response of an organism, relieve anxiety and nervous mood and promote sleep; part of the components in the formula have anti-inflammatory and antioxidant activity, can relieve brain nerve inflammatory response, reduce damage of free radicals to nerve cells, protect nerve cell functions, and provide a good intra-nerve environment for sleep improvement.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition product for treating insomnia symptoms. Background Art

[0002] Insomnia is a common sleep disorder that seriously affects people's quality of life, physical and mental health. Currently, there are many drugs for treating insomnia on the market. Although Western medicines such as Rohypnol tablets and Estazolam tablets have certain curative effects, long-term use is likely to cause adverse reactions such as drug dependence and immune disorder in patients. Traditional Chinese medicine has the advantages of multi-target and overall conditioning in the treatment of insomnia, but the existing traditional Chinese medicine insomnia treatment programs have problems such as inaccurate curative effects and unreasonable formulas. Summary of the Invention

[0003] The purpose of the present invention is to solve the deficiencies in the prior art, and a traditional Chinese medicine composition product for treating insomnia symptoms is proposed. The technical solution adopted by the present invention is as follows:

[0004] A traditional Chinese medicine composition product for treating insomnia symptoms, the traditional Chinese medicine formula includes Phellodendron amurense, raw fossil fragments, raw oyster, raw malt, Nardostachys jatamansi, Patrinia scabiosaefolia, and liquorice;

[0005] The weight parts of the traditional Chinese medicine formula are: 9 - 12 g of Phellodendron amurense, 18 - 20 g of raw fossil fragments, 18 - 20 g of raw oyster, 9 - 12 g of raw malt, 20 - 30 g of Nardostachys jatamansi, 13 - 15 g of Patrinia scabiosaefolia, and 3 - 5 g of liquorice.

[0006] As an improvement, the traditional Chinese medicine composition product is made into capsules, and each capsule weighs 0.5 grams.

[0007] As an improvement, the preparation method is as follows:

[0008] Step 1: Weigh Phellodendron amurense, raw fossil fragments, raw oyster, raw malt, Nardostachys jatamansi, Patrinia scabiosaefolia, and liquorice according to the above weight parts.

[0009] Step 2: Use an extraction process to extract each traditional Chinese medicine to obtain an extract of the active ingredients.

[0010] Step 3: Concentrate and dry the extract to make an extract powder.

[0011] Step 4: Add appropriate excipients to the extract powder, mix evenly, and make granules.

[0012] Step 5: After drying and sizing the granules, fill them into capsules to make capsules with a specification of 0.5 g.

[0013] The beneficial effects of the present invention are:

[0014] The present invention relates to a traditional Chinese medicine composition product for treating insomnia symptoms. A variety of components in this prescription can regulate the synthesis, release, and uptake of neurotransmitters such as serotonin, gamma-aminobutyric acid, and dopamine in the brain, maintain the balance of neurotransmitters, and thus improve sleep.

[0015] This prescription can regulate the function of the HPA axis, reduce the secretion level of stress hormones such as cortisol under stress, relieve the body's stress response, alleviate anxiety and tension, and promote sleep.

[0016] Some components in the formula have anti-inflammatory and antioxidant activities, can reduce the inflammatory response of brain nerves, reduce the damage of free radicals to nerve cells, protect the function of nerve cells, and provide a good neural internal environment for sleep improvement. Detailed implementation mode

[0017] To make the content of the present invention easier to be clearly understood, the following will combine the embodiments of the present invention and describe the technical solutions in the embodiments of the present invention clearly and completely.

[0018] The proportion of the traditional Chinese medicine formula is: Cortex Phellodendri Chinensis 9 - 12g, Os Draconis 18 - 20g, Concha Ostreae 18 - 20g, Fructus Hordei Germinatus 9 - 12g, Radix Nardostachyos 20 - 30g, Herba Patriniae 13 - 15g, and Radix Glycyrrhizae 3 - 5g.

[0019] The traditional Chinese medicine composition product is made into capsules, and each capsule weighs 0.5 grams.

[0020] Cortex Phellodendri Chinensis: It has the effects of clearing heat and drying dampness, purging fire and detoxifying, etc. In the formula, it can purge ministerial fire and make the mind peaceful.

[0021] Raw Os Draconis and Concha Ostreae: They have the effects of calming the mind by heavy sedation and suppressing the hyperactive liver-yang, can suppress the floating yang qi, and make the spirit return to its dwelling place.

[0022] Fructus Hordei Germinatus: Soothing the liver and regulating the middle, can regulate emotions and relieve sleep disorders caused by liver depression.

[0023] Radix Nardostachyos: Regulating qi to relieve pain, awakening the spleen and strengthening the stomach, its fragrance can arouse the spirit and regulate qi, which helps to improve sleep.

[0024] Herba Patriniae: Clearing heat and detoxifying, removing stasis and discharging pus, can clear the internal heat in the body and improve the sleep environment.

[0025] Radix Glycyrrhizae: Harmonizing all the drugs, invigorating the spleen and replenishing qi, and moderating the properties of the drugs.

[0026] Weigh Cortex Phellodendri Chinensis, Os Draconis, Concha Ostreae, Fructus Hordei Germinatus, Radix Nardostachyos, Herba Patriniae, and Radix Glycyrrhizae according to the above weight parts.

[0027] Use a specific extraction process (such as water extraction, alcohol extraction, or a combination of the two) to extract each traditional Chinese medicine to obtain an extract of the active ingredients.

[0028] The extract is concentrated and dried to make an extract powder.

[0029] An appropriate amount of excipients (such as starch, dextrin, etc.) is added to the extract powder and mixed evenly to make granules.

[0030] After the granules are dried and sized, they are filled into capsules to make a 0.5g specification capsule preparation.

[0031] Sleep improvement time effect: Clinical trials show that general patients can feel mental peace after taking the medicine for 1 - 6 hours and gradually enter a sound sleep state; although severe patients do not fully fall asleep within 1 - 6 hours after the first dose, the uncomfortable symptoms of the brain (such as dizziness, brain swelling, restlessness, etc.) will be significantly reduced, and they can gradually enter a stable sleep state after taking the medicine continuously for 3 - 7 days.

[0032] Effect after drug withdrawal: After sleep improvement, through 1 - 2 months of follow - up observation, most patients have no obvious recurrence after drug withdrawal, the sleep quality remains good, the drug effect lasts for 7 - 10 days, and through long - term clinical observation, no drug dependence, addiction and obvious drug resistance have been found.

[0033] Improvement of accompanying symptoms: It can effectively relieve symptoms such as headache, head swelling, blood pressure fluctuation, anxiety and depression, memory loss caused by long - term sleep disorder, and improve the quality of life and work / learning ability of patients.

[0034] Multiple components in this prescription can regulate the synthesis, release and uptake of neurotransmitters such as 5 - hydroxytryptamine, γ - aminobutyric acid, dopamine in the brain, maintain the balance of neurotransmitters, and thus improve sleep;

[0035] This prescription can regulate the function of the HPA axis, reduce the secretion level of stress hormones such as cortisol under stress, relieve the body's stress response, reduce anxiety and tension, and promote sleep;

[0036] Some components in the formula have anti - inflammatory and antioxidant activities, can reduce the brain nerve inflammatory reaction, reduce the damage of free radicals to nerve cells, protect the function of nerve cells, and provide a good nerve internal environment for sleep improvement.

[0037] The above are only the preferred embodiments of this invention patent and are not used to limit this invention patent. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of this invention patent shall be included within the protection scope of this invention patent.

Claims

1. A traditional Chinese medicine composition product for treating insomnia symptoms, characterized in that, The traditional Chinese medicine formula includes Phellodendri Chinensis Cortex, raw fossil fragments, raw oyster, raw malt, Nardostachyos Root and Rhizome, Patriniae Herba, and liquorice. The parts by weight of the traditional Chinese medicine formula are as follows: 9 - 12 g of Phellodendri Chinensis Cortex, 18 - 20 g of raw fossil fragments, 18 - 20 g of raw oyster, 9 - 12 g of raw malt, 20 - 30 g of Nardostachyos Root and Rhizome, 13 - 15 g of Patriniae Herba, and 3 - 5 g of liquorice.

2. The traditional Chinese medicine composition product for treating insomnia symptoms according to claim 1, wherein, The traditional Chinese medicine composition is made into capsules, and each capsule weighs 0.5 grams.

3. The traditional Chinese medicine composition product for treating insomnia symptoms according to claim 1, characterized in that, The preparation method is as follows: Step 1: Weigh Phellodendri Chinensis Cortex, raw fossil fragments, raw oyster, raw malt, Nardostachyos Root and Rhizome, Patriniae Herba, and liquorice according to the above parts by weight. Step 2: Use an extraction process to extract each traditional Chinese medicine to obtain an extract of active ingredients. Step 3: Concentrate and dry the extract to make an extract powder. Step 4: Add appropriate excipients to the extract powder, mix evenly, and make granules. Step 5: After drying and sizing the granules, fill them into capsules to make capsules with a specification of 0.5 g.