An isolated transposase AG-TEF11 and uses thereof

Abstract

An isolated transposase and uses thereof are provided. Also provided are nucleic acids and nucleic acid constructs encoding the transposase, nucleic acid panels and nucleic acid panel constructs, compositions, recombinant vectors, recombinant host cells and kits comprising the transposase. Also provided are a method for introducing an exogenous nucleic acid fragment into a genome of a host cell, a method for editing a genome of a host cell and a method for obtaining a host cell containing an exogenous nucleic acid fragment in a genome. Also provided are uses of the transposase, nucleic acids and nucleic acid constructs, nucleic acid panels and nucleic acid panel constructs, compositions, recombinant vectors or recombinant host cells for introducing an exogenous nucleic acid fragment gene into a genome of a host cell or for preparing a medicament or a preparation for gene therapy, cell therapy, genomic research or stem cell induction and post-induction differentiation.

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