Left auricle closer

Abstract

The invention discloses a left atrial appendage closer, and belongs to the field of medical instruments. The left auricle closer comprises a conveying catheter, a supporting pipe, a supporting disc, a telescopic supporting rod, a closing clamp assembly and a control pull wire, a closing clamp can be fed into an opening of a left auricle through the conveying catheter, and the opening of the left auricle is opened through cooperation of the telescopic supporting rod and the control pull wire; according to the left atrial appendage closure device, the puncture hook needle in the closure clamp is used for puncturing the tissue wall of the left atrial appendage opening to achieve combination, finally the left atrial appendage opening is closed through linear closing of the closure clamp, and compared with an existing left atrial appendage closure device, the puncture hook needle on the periphery of the closure clamp can puncture the tissue in the radial direction, the closure clamp is used for driving the left atrial appendage opening to be closed, and the left atrial appendage opening is closed. The left atrial appendage closing clamp has the advantages that the left atrial appendage closing clamp is more firmly connected with the left atrial appendage and is not easy to fall off, the problem that the sealing reliability of the left atrial appendage is reduced due to looseness or movement is solved, long-term effectiveness of left atrial appendage closing is guaranteed, and complications caused by falling off and unreliable sealing are reduced.

Description

Technical Field

[0001] The present invention relates to a medical device, and more particularly to a left atrial appendage closure device, which is mainly used for closing and blocking the left atrial appendage. Background Art

[0002] The atrial appendage is a protrusion of the atrium of the human heart, which is divided into the right atrial appendage and the left atrial appendage. The right atrial appendage is adjacent to the ascending aorta, and the left atrial appendage is located next to the pulmonary artery trunk. The left atrial appendage is a common source of blood clots, which can lead to stroke, especially in patients with atrial fibrillation. In order to prevent stroke in the case of atrial fibrillation, closing the left atrial appendage is an effective treatment. At present, the main technologies used to close the left atrial appendage are: surgical left atrial appendage resection and transcatheter left atrial appendage occlusion. Surgical resection of the left atrial appendage has the disadvantages of large trauma and many complications and is basically not used; transcatheter left atrial appendage occlusion is a minimally invasive treatment and has become the main means of closing the left atrial appendage. It has been greatly developed, and many medical devices for left atrial appendage occlusion have emerged.

[0003] For example, the patent application entitled "Device for Preventing Embolic Material from Passing Through the Left Atrial Appendage of a Patient" disclosed in Chinese Patent Publication No. CN1342056A (publication date March 27, 2002) has an expandable body with an outer peripheral edge, the size and structure of the expandable body being made to engage the surface of the patient's left atrial appendage when expanded, and a barrier layer arranged on the expandable body to prevent embolic material from passing through the left atrial appendage. Similar left atrial appendage occlusion devices also include: "Left atrial appendage occluder" disclosed by Chinese Patent Publication No. CN102805654A (publication date: December 5, 2012), "Occlusion device and related deployment method" disclosed by Chinese Patent Publication No. CN103607962A (publication date: February 26, 2014), "Double umbrella left atrial appendage closure device" disclosed by Chinese Patent Publication No. CN104107072A (publication date: October 22, 2014), and "Left atrial appendage occluder" disclosed by Chinese Patent Publication No. CN106923883A (publication date: July 7, 2017), etc. The above-mentioned left atrial appendage occlusion devices mainly use seals to seal the neck of the left atrial appendage, and use structures such as barbs to prevent the seals from falling off. When implanted, they can be percutaneously punctured and delivered to the left atrial appendage opening via a catheter, and then implanted for occlusion. They have the advantages of short operation time and high success rate.

[0004] Although the aforementioned LAA occlusion devices have been widely used clinically, occluder dislodgement remains one of the most serious complications. This is primarily due to a mismatch between the device size and the patient's LAA, preventing the barbs on the device from effectively implanting and securing the device. Furthermore, it is currently difficult to customize the occluder to suit the LAA size of each patient. Furthermore, the sealing portion of existing LAA occluders is often a cap or plug located at the neck opening of the LAA. Over time, if the LAA occluder moves or becomes loose, the sealing reliability can be compromised, thus affecting the device's long-term effectiveness. Summary of the Invention

[0005] 1. Technical problem to be solved by the invention

[0006] The object of the present invention is to overcome the above-mentioned shortcomings of the existing left atrial appendage occluder and provide a left atrial appendage closure device. The technical solution of the present invention is adopted to replace the previous left atrial appendage occlusion technology with the closure technology of the left atrial appendage by using a closure clip, thereby ensuring the reliability and long-term effectiveness of the left atrial appendage closure. Specifically, the closure clip can be delivered to the opening of the left atrial appendage in a closed state using a delivery catheter, and is stretched at the left atrial appendage opening through the cooperation of a telescopic support rod and a control pull wire. The puncture hook needle inside the closure clip is used to pierce the tissue wall of the left atrial appendage opening to achieve bonding. Finally, the "one" closure of the closure clip is used to achieve the closure of the left atrial appendage opening. Compared with the existing left atrial appendage occluder, the puncture hook needle on the outer periphery of the closure clip can pierce the tissue in the radial direction, and the closure of the closure clip is used to drive the closure of the left atrial appendage opening, so that the connection between the closure clip and the left atrial appendage is more secure and not easy to fall off. At the same time, there is no problem of reduced reliability of the left atrial appendage sealing due to loosening or movement, thereby ensuring the long-term effectiveness of the left atrial appendage closure and reducing the complications caused by falling off and unreliable sealing.

[0007] 2. Technical solution

[0008] In order to achieve the above object, the technical solution provided by the present invention is:

[0009] A left atrial appendage closure device of the present invention comprises

[0010] A delivery catheter having a sleeve at its front end;

[0011] The support tube is inserted into the delivery tube and is used to be delivered to a designated position under the guidance of the delivery tube;

[0012] The support plate is installed at the front end of the support tube and has a number of connecting seats distributed circumferentially;

[0013] A telescopic support rod, one end of which is mounted on a corresponding connecting seat of the support disc via a rotating seat, each of the telescopic support rods having a folded state converging toward the center and an extended state radiating radially relative to the support disc, the folded state and the extended state being switchable by rotating the telescopic support rod; each of the telescopic support rods also has a locking assembly for maintaining the telescopic support rod in a stretched state and capable of triggering unlocking to retract the telescopic support rod;

[0014] The closing clamp assembly includes a tubular closing ring, a needle rod capable of being pulled is installed in the closing ring, the needle rod has a plurality of puncture hook needles, the outer side of the closing ring has a plurality of hook needle extrusion holes corresponding to the positions of the puncture hook needles, and the closing ring also has an interlocking assembly for maintaining the closing ring in a "one" closed state; the closing ring in the closed state and the telescopic support rod in the retracted state are accommodated in the above-mentioned sleeve, and can be pushed forward by the support tube.

[0015] The control pull wire includes a closing clamp opening and closing pull wire, a hook pull wire and a locking pull wire located in the support tube, the front end of the closing clamp opening and closing pull wire passes through the corresponding telescopic support rod and is connected to the closing ring, and is used to make the free end of the corresponding telescopic support rod dock with the closing ring by tightening the corresponding closing clamp opening and closing pull wire, and to expand the closing ring when the telescopic support rod is converted to the expanded state; the closing clamp opening and closing pull wire can also cooperate with the contraction of the telescopic support rod to control the closing of the closing ring to the "one" closed state after the above-mentioned locking assembly is unlocked; the front end of the hook pull wire passes through the support disk and is connected to the needle rod in the closing ring, and is used to pull the needle rod to make the puncture hook needle pierce the corresponding hook needle extrusion hole when the closing ring is in the expanded state; the front end of the locking pull wire is connected to the interlocking assembly on the closing ring, and is used to control the interlocking assembly to be engaged or disengaged through the locking pull wire.

[0016] Furthermore, the delivery catheter also includes a hypotube, and the sleeve is installed at the front end of the hypotube.

[0017] Furthermore, a core rod mounting hole is provided in the center of the support plate, and a core rod capable of axial movement is provided in the core rod mounting hole. The tail of the core rod is connected to a core rod push-pull rod, and the core rod also has a first wire outlet hole and a second wire outlet hole passing through its front end face. The hook wire is passed through the first wire outlet hole, and the lock wire is passed through the second wire outlet hole.

[0018] Furthermore, two needle rods are centrally symmetrically provided in the closed circle, and the outer side of the closed circle has two oppositely arranged needle rod mounting holes. The needle rod is installed in the closed circle through the corresponding needle rod mounting holes along the direction of the puncture crochet needle. The inner side of the closed circle also has a crochet needle pulling hole opposite to the above-mentioned needle rod mounting hole. The crochet needle pulling wire is connected to one end of the corresponding needle rod through the corresponding crochet needle pulling hole, and is used to pull the needle rod to move in the direction opposite to the puncture crochet needle so that the puncture crochet needle can pierce the corresponding crochet needle extrusion hole.

[0019] Furthermore, a plurality of support rod connecting holes are distributed on the inner side of the closing loop, and the closing clamp opening and closing pull wires pass through the corresponding telescopic support rods and are connected to the corresponding support rod connecting holes; after the closing loop in the closed state and the telescopic support rod in the retracted state are pushed out of the sleeve, the direction of the closing loop is controlled by pulling the two closing clamp opening and closing pull wires located in the middle of the closing loop in the closed state.

[0020] Furthermore, the interlocking assembly includes an upper lock buckle and a lower lock buckle that can be engaged with each other, and the upper lock buckle and the lower lock buckle are respectively arranged on the closed circle and located in the middle position of the corresponding needle rod; the upper lock buckle and the lower lock buckle are each connected to a lock buckle pull wire, and the upper lock buckle and the lower lock buckle are deformed by pulling the lock buckle pull wire to engage or disengage.

[0021] Furthermore, the telescopic support rod has at least two sections of support tubes that are sleeved with each other, and a locking assembly is provided between two adjacent sections of the support tubes, and the locking assembly includes a plurality of locking blocks distributed along the circumference, each of the locking blocks is embraced together by a hoop, and the hoop is provided at the tail end of the support tube located on the inner side, and the inner side of each locking block has an inner conical surface that encloses a tapered hole, and the end of the locking block extending outward from the tail end of the support tube has a locking flange extending outward, and the inner side of the front end of the support tube located on the outer side is provided with a locking groove that can cooperate with the locking flange, and the end of each locking block away from the locking flange is elastically locked. The elastic rings are converged inwardly and connected together so that each locking block has an elastic tendency to rotate around the hoop and cause the locking flange to expand outward; when each support tube is in a stretched state, the locking flange is engaged in the corresponding locking groove; the telescopic support rod is also provided with an unlocking trigger rod that can be pressed axially, and the tail end of the unlocking trigger rod has a pressing part, and the front end has a trigger part that cooperates with the inner conical surface of each locking block, and the unlocking trigger rod is driven by axially pressing to drive the trigger part to extend into the tapered hole surrounded by each locking block, prompting each locking block to rotate around the hoop, causing the locking flange to disengage and unlock from the locking groove.

[0022] Furthermore, the unlocking trigger rod is arranged in the support tube closest to the support plate in the telescopic support rod, and the tail end of the support tube is provided with a tail sleeve and a return spring. The unlocking trigger rod passes through the tail sleeve, and the return spring is sleeved on the unlocking trigger rod, and one end of the return spring acts on the tail sleeve, and the other end acts on the pressing part, which is used to drive the unlocking trigger rod to reset after being pressed.

[0023] Furthermore, the support plate is also provided with 90° guide holes corresponding to the positions of each telescopic support rod, and the radial opening of each 90° guide hole in the support plate is opposite to the tail end of the telescopic support rod in the expanded state; the support tube is provided with an unlocking operating rod, and the front end of the unlocking operating rod has a flexible pressing section, which is passed through the corresponding 90° guide hole. The pressing movement of the unlocking operating rod drives each flexible pressing section to extend from the radial hole of the 90° guide hole and drives the corresponding unlocking trigger rod to perform a press-to-unlock action.

[0024] Furthermore, short shafts are respectively provided on both sides of the connecting seat, and the rotating seat has a rotating shaft hole that rotates with the short shaft. The connecting seat also has an axial hole running through it from top to bottom, and the axial hole intersects with the 90° guide hole, and a wire groove connecting the axial hole and the corresponding radial hole is provided on the upper side of the connecting seat. When the telescopic support rod switches from a retracted state to an expanded state, the closing clamp opening and closing pull wire passing through the axial hole passes through the wire groove and enters the radial hole.

[0025] 3. Beneficial effects

[0026] Compared with the existing known technologies, the technical solution provided by the present invention has the following significant effects:

[0027] (1) A left atrial appendage closure device of the present invention uses a closure clamp to close the left atrial appendage instead of the previous left atrial appendage occlusion technology, thereby ensuring the reliability and long-term effectiveness of the left atrial appendage closure; specifically, it includes a delivery catheter, a support tube, a support plate, a telescopic support rod, a closure clamp assembly and a control pull wire. The closure clamp can be delivered to the opening of the left atrial appendage in a closed state by using the delivery catheter, and is stretched at the left atrial appendage opening by the cooperation of the telescopic support rod and the control pull wire. The puncture hook needle inside the closure clamp is used to pierce the tissue wall of the left atrial appendage opening to achieve bonding. Finally, the "one" closure of the closure clamp is used to achieve the closure of the left atrial appendage opening. Compared with the existing left atrial appendage occluder, the puncture hook needle on the periphery of the closure clamp can penetrate the tissue in the radial direction, and the closure of the left atrial appendage opening is driven by the closure of the closure clamp, so that the connection between the closure clamp and the left atrial appendage is more reliable and not easy to fall off. At the same time, there is no problem of reduced reliability of the left atrial appendage sealing due to loosening or movement, thereby ensuring the long-term effectiveness of the left atrial appendage closure and reducing complications caused by falling off and unreliable sealing.

[0028] (2) A left atrial appendage closure device of the present invention utilizes a support tube and a control pull line to operate the entire left atrial appendage closure device, and realizes different operating actions through a closing clamp opening and closing pull line, a hook pull line, and a lock pull line, making the left atrial appendage closure operation simple, convenient, flexible, and easy to control;

[0029] (3) A left atrial appendage closure device of the present invention has a delivery catheter comprising a hypotube and a cannula, wherein the cannula is mounted at the front end of the hypotube. The hypotube can be used to flexibly and accurately deliver the closure device to a designated position, with high control accuracy, minimal surgical trauma, and safety and reliability.

[0030] (4) A left atrial appendage closure device of the present invention has a core rod mounting hole at the center of its support disk, a core rod capable of axial movement is provided in the core rod mounting hole, the tail of the core rod is connected to a core rod push-pull rod, and the core rod also has a first wire outlet hole and a second wire outlet hole passing through its front end surface, the hook wire is passed through the first wire outlet hole, and the lock wire is passed through the second wire outlet hole. The wire outlet position of the wire can be adjusted by using the core rod, which is convenient for controlling the force direction of the wire, thereby ensuring the operational flexibility and labor-saving of the wire, and improving the accuracy of the closing clamp on the left atrial appendage;

[0031] (5) A left atrial appendage closure device of the present invention has two needle rods symmetrically arranged in the center of the closing circle, and two needle rod mounting holes arranged oppositely on the outside of the closing circle. The needle rod is installed in the closing circle along the direction of the puncture hook needle through the corresponding needle rod mounting holes. The above design can facilitate the assembly of the needle rod on the one hand, and can also improve the strength of both sides of the closing circle by utilizing the needle rod, so that the closing circle can naturally bend and close at the weak area where the needle rod mounting holes are located when closing, thereby improving the closing tightness of the closing clamp; in addition, the inner side of the closing circle also has a hook wire hole corresponding to the position of the above needle rod mounting holes, and the hook wire is connected to one end of the corresponding needle rod through the corresponding hook wire hole, and is used to pull the needle rod to move in the direction opposite to the puncture hook needle so that the puncture hook needle pierces the corresponding hook needle extrusion hole, making the pulling operation of the needle rod simple and convenient, and can stably realize the extension of the puncture hook needle and firmly penetrate the tissue, thereby ensuring the firmness of the combination between the closing circle and the left atrial appendage tissue wall;

[0032] (6) A left atrial appendage closure device of the present invention has a plurality of support rod connection holes distributed on the inner side of its closing ring. The closing clamp opening and closing pull wires pass through the corresponding telescopic support rods and are connected to the corresponding support rod connection holes, so that the free end of the telescopic support rod can be stably combined with the closing ring, thereby realizing the stable expansion of the closing ring. Moreover, after the closing ring in the closed state and the telescopic support rod in the retracted state are pushed out of the sleeve, the direction of the closing ring is controlled by pulling the two closing clamp opening and closing pull wires located in the middle of the closing ring in the closed state, so that the relative position of the closing ring and the left atrial appendage opening can be adjusted by controlling the direction of the closing ring, thereby ensuring the implantation accuracy of the closing ring.

[0033] (7) A left atrial appendage closure device of the present invention, wherein the interlocking assembly comprises an upper lock buckle and a lower lock buckle that can be interlocked and connected with each other, the upper lock buckle and the lower lock buckle are respectively arranged on the closing ring and located in the middle position of the corresponding needle rod; the upper lock buckle and the lower lock buckle are each connected to a lock buckle pull wire, and the upper lock buckle and the lower lock buckle are deformed by the lock buckle pull wire to engage or disengage, and the interlocking assembly adopts a mechanical interlocking structure, and the locking direction is the closing deformation direction of the closing ring, so that the closing ring is locked firmly and reliably when closed and is not easy to loosen, and the pulling direction of the lock buckle pull wire on the upper and lower lock buckles is the vertical direction of the closing ring, which can easily realize the engagement or disengagement control of the upper and lower lock buckles;

[0034] (8) A left atrial appendage closure device of the present invention has a telescopic support rod with at least two sections of support tubes that are sleeved with each other, and a locking assembly is provided between the two adjacent sections of the support tubes, which can ensure the stability of the telescopic support rod in the stretched state, and facilitate the use of the telescopic support rod to support the closing ring to keep it in a circular expanded state; at the same time, the locking assembly can be unlocked by pressing the telescopic support rod to shrink the telescopic support rod, so that the closing ring is closed into a "one" shape, and the operation stability is good; in addition, the above-mentioned locking assembly has a simple and compact structural design and can be installed in a telescopic support rod with a small diameter; and the structural design is ingenious, and the multi-stage locking assembly can be unlocked by pressing the unlocking trigger rod, which is easy to operate;

[0035] (9) A left atrial appendage closure device of the present invention has an unlocking trigger rod arranged in a support tube closest to the support plate in the telescopic support rod, a tail sleeve and a return spring are provided at the tail end of the support tube, the unlocking trigger rod passes through the tail sleeve, the return spring is sleeved on the unlocking trigger rod, and one end of the return spring acts on the tail sleeve and the other end acts on the pressing part to drive the unlocking trigger rod to reset after being pressed. The unlocking trigger rod has good pressing feedback performance, which further improves the convenience of surgical operation;

[0036] (10) A left atrial appendage closure device of the present invention is further provided with 90° guide holes corresponding to the positions of each telescopic support rod on its support disk, and the radial opening of each 90° guide hole in the support disk is opposite to the tail end of the telescopic support rod in the expanded state; an unlocking operating rod is provided in the support tube, and the front end of the unlocking operating rod has a flexible pressing section, which is passed through the corresponding 90° guide hole. The pressing movement of the unlocking operating rod drives each flexible pressing section to extend from the radial hole of the 90° guide hole and drives the corresponding unlocking trigger rod to perform a press-unlocking action. The unlocking operating rod is used to facilitate the unlocking operation of the telescopic support rod from the outside, and has the advantages of simple structure and convenient operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Figure 1 This is a schematic diagram of the overall assembly state of a left atrial appendage closure device of the present invention;

[0038] Figure 2 Schematic diagram of the assembly state of a left atrial appendage closure device of the present invention (the delivery catheter is omitted);

[0039] Figure 3 Schematic diagram of the structure of the front component of a left atrial appendage closure device of the present invention;

[0040] Figure 4 Schematic diagram of the assembly structure of the support plate and each telescopic support rod in the present invention;

[0041] Figure 5 It is a cross-sectional structural schematic diagram of the telescopic support rod in the present invention in a retracted state on the support plate;

[0042] Figure 6 Schematic diagram of the three-dimensional structure of the support plate in the present invention;

[0043] Figure 7 This is a schematic structural diagram of the telescopic support rod in the present invention in a stretched state;

[0044] Figure 8 for Figure 7 Schematic diagram of the cross-sectional structure in the AA direction;

[0045] Figure 9 for Figure 8 Schematic diagram of the local enlarged structure at K in the middle;

[0046] Figure 10 Schematic diagram of the structure of the telescopic support rod in the present invention in a retracted state;

[0047] Figure 11 for Figure 10 Schematic diagram of the cross-sectional structure in the middle BB direction;

[0048] Figure 12 Schematic diagram of the split structure of the locking assembly and the adjacent support tube in the present invention (top view);

[0049] Figure 13 Schematic diagram of the split structure of the locking assembly and the adjacent support tube in the present invention (looking from above);

[0050] Figure 14 This is a schematic structural diagram of the closing clamp assembly in the present invention in an initial closed state;

[0051] Figure 15 Schematic diagram of the structure of the closing clamp assembly of the present invention in the closed state (puncture hook needle inserted state);

[0052] Figure 16 Schematic diagram of the structure of the needle rod and the puncture hook thereon in the present invention;

[0053] Figure 17This is a schematic structural diagram of the closing clip assembly in the present invention in an open state;

[0054] Figure 18 It is a cross-sectional structural schematic diagram of the telescopic support rod in the present invention in an expanded state on the support plate;

[0055] Figure 19 This is a schematic diagram of the operation of a left atrial appendage closure device of the present invention in a state where the closure clip is expanded.

[0056] Explanation of the numbers in the schematic diagram:

[0057] 1. Conveying catheter; 1a. Hypotube; 1b. Casing; 2. Support tube; 3. Support plate; 3-1. Connecting seat; 3-1a. Short shaft; 3-1b. Axial hole; 3-1c. Radial hole; 3-1d. Wire groove; 3-2. Wire hole; 3-3. Core rod mounting hole; 3-4. 90° guide hole; 4. Telescopic support rod; 4a. Rotating seat; 4a-1. Rotating axis hole; 4-1. First support tube; 4-2. Second support tube; 4-3. Third support tube; 4-4. Unlocking trigger lever; 4-4a. Pressing part; 4-4b. Triggering part; 4-5. Tail sleeve; 4-6. Return spring; 4-7. Locking assembly; 4-7-1. Locking block; 4-7-1a. Inner conical surface; 4-7-1b, locking flange; 4-7-2, hoop; 4-7-3, elastic ring; 4-8, locking slot; 4-9, ring groove; 5, core rod; 5a, first wire outlet hole; 5b, second wire outlet hole; 6, closing clamp assembly; 6-1, closing ring; 6-1a, needle rod mounting hole; 6-1b, hook wire hole; 6-1c, hook extrusion hole; 6-1d, support rod connecting hole; 6-2, needle rod; 6-2a, puncture hook; 6-3, upper locking buckle; 6-4, lower locking buckle; 7, control pull line; 7a, closing clamp opening and closing pull line; 7b, hook pull line; 7c, lock pull line; 8, core rod push-pull rod; 9, unlocking operating lever; 9-1, flexible pressing section. DETAILED DESCRIPTION

[0058] In order to further understand the content of the present invention, the present invention is described in detail with reference to the accompanying drawings and embodiments.

[0059] [Example]

[0060] The left atrial appendage closure device of this embodiment is mainly used to close the left atrial appendage opening to eliminate the source of thrombus formation. Figure 1 、 Figure 2 and Figure 3 As shown, the left atrial appendage closure device mainly includes a delivery catheter 1, a support tube 2, a support plate 3, a telescopic support rod 4, a closure clamp assembly 6 and a control pull wire 7, wherein:

[0061] The delivery catheter 1 is used to penetrate the tissue through the puncture device to establish a channel for delivering other instruments to the designated location (left atrial appendage). The front end of the delivery catheter 1 has a cannula 1b, which is used to accommodate the front component of the left atrial appendage closure device (see Figure 1 shown);

[0062] The support tube 2 is inserted into the delivery catheter 1 and is used to be delivered to the designated position under the guidance of the delivery catheter 1. The support tube 2 can control the forward and backward movement of the front component and adjust the implantation position.

[0063] The support plate 3 is installed at the front end of the support tube 2, and has a plurality of connection seats 3-1 distributed circumferentially. The connection seats 3-1 are preferably evenly distributed on the support plate 3, preferably 8 to 12.

[0064] One end of the telescopic support rod 4 is mounted on the corresponding connecting seat 3-1 of the support disk 3 through a rotating seat 4a, and each telescopic support rod 4 has a folded state gathered toward the center and an expanded state radiating radially relative to the support disk 3, and the folded state and the expanded state can be switched by rotating the telescopic support rod 4; the telescopic support rods 4 in the folded state are gathered together and can be stored in the sleeve 1b, and the telescopic support rods 4 in the expanded state are roughly perpendicular to the support tube 2, and each telescopic support rod 4 can be expanded to form a radial structure for stretching the closing clamp assembly 6; in addition, each telescopic support rod 4 also has a locking component 4-7 for keeping the telescopic support rod 4 in the stretched state and capable of triggering unlocking to retract the telescopic support rod 4; when the locking component 4-7 is in the locked state, the telescopic support rod 4 is kept in the stretched state and cannot be retracted, and the retraction of the telescopic support rod 4 can be achieved only after the locking component 4-7 is unlocked; Figures 1 to 3 As shown, in the initial state, each telescopic support rod 4 is kept in a stretched state under the action of the locking assembly 4-7;

[0065] The closing clamp assembly 6 is used to close the left atrial appendage orifice, and includes a tubular closing ring 6-1, a needle rod 6-2 that can be pulled is installed in the closing ring 6-1, and a plurality of puncture hooks 6-2a are provided on the needle rod 6-2. The outer side of the closing ring 6-1 has a plurality of hook extrusion holes 6-1c corresponding to the positions of the puncture hooks 6-2a. The puncture hooks 6-2a pass through the closing ring 6-1 to form a hook structure (such as Figure 15 As shown in FIG, the closing ring 6-1 is connected to the tissue wall of the left atrial appendage; the closing ring 6-1 is also provided with an interlocking component for keeping the closing ring 6-1 in a "I" closed state, so that the originally open left atrial appendage neck can be closed into a "I" shaped seam under the action of the closing ring 6-1, thereby achieving the closure of the left atrial appendage; the closed state closing ring 6-1 and the retracted state telescopic support rod 4 are accommodated in the above-mentioned sleeve 1b (as shown in FIG. Figure 1As shown), the sleeve 1b can be pushed forward under the action of the support tube 2; after the closed ring 6-1 in the closed state and the telescopic support rod 4 in the retracted state are pushed out from the sleeve 1b, the closed ring 6-1 and the telescopic support rod 4, which are no longer constrained by the sleeve 1b, can be expanded by controlling the pull wire 7;

[0066] The control pull wire 7 includes a closing clamp opening and closing pull wire 7a, a hook pull wire 7b and a lock pull wire 7c located in the support tube 2. The front end of the closing clamp opening and closing pull wire 7a passes through the corresponding telescopic support rod 4 and is connected to the closing ring 6-1. It is used to make the free end of the corresponding telescopic support rod 4 dock with the closing ring 6-1 by tightening the corresponding closing clamp opening and closing pull wire 7a, and to open the closing ring 6-1 when the telescopic support rod 4 is converted to the expanded state; the closing clamp opening and closing pull wire 7a can also be used in the above-mentioned lock assembly 4- After 7 is unlocked, it cooperates with the contraction of the telescopic support rod 4 to control the closing of the closed loop 6-1 to the "I" closed state; the front end of the hook pull wire 7b passes through the support disk 3 and is connected to the needle rod 6-2 in the closed loop 6-1, which is used to pull the needle rod 6-2 when the closed loop 6-1 is in the expanded state so that the puncture hook 6-2a pierces the corresponding hook extrusion hole 6-1c; the front end of the lock pull wire 7c is connected to the interlocking component on the closed loop 6-1, which is used to control the interlocking component to be engaged or disengaged through the lock pull wire 7c.

[0067] Based on the above-mentioned left atrial appendage closure device, the closure of the left atrial appendage can be replaced by the closure clamp to replace the previous left atrial appendage occlusion technology, thereby ensuring the reliability and long-term effectiveness of the left atrial appendage closure. Specifically, the closure clamp can be delivered to the opening of the left atrial appendage using the delivery catheter 1 in a closed state, and can be stretched at the left atrial appendage opening through the cooperation of the telescopic support rod 4 and the control pull wire 7. The puncture hook 6-2a inside the closure clamp is used to pierce the tissue wall of the left atrial appendage opening to achieve bonding, and finally the "one" closure of the closure clamp is used to achieve the closure of the left atrial appendage opening. Compared with the existing left atrial appendage occluder, the puncture hook 6-2a on the periphery of the closure clamp can penetrate the tissue in the radial direction, and the closure of the closure clamp is used to drive the closure of the left atrial appendage opening, so that the connection between the closure clamp and the left atrial appendage is more reliable and not easy to fall off. At the same time, there is no problem of reduced reliability of the left atrial appendage sealing due to loosening or movement, thereby ensuring the long-term effectiveness of the left atrial appendage closure and reducing the complications caused by falling off and unreliable sealing. In addition, the support tube 2 and the control pull wire 7 are used to operate the entire left atrial appendage closure device, and different operating actions are achieved through the closing clamp opening and closing pull wire 7a, the hook pull wire 7b and the lock pull wire 7c, making the left atrial appendage closure operation simple, convenient, flexible and easy to control.

[0068] like Figure 1As shown, in this embodiment, the delivery catheter 1 also includes a hypotube 1a, with a cannula 1b mounted at the front end of the hypotube 1a. The hypotube 1a is an existing product that can be moved within the blood vessel with excellent controllability. The direction of the hypotube 1a can also be controlled using a pull wire. Using the hypotube 1a, the occluder can be flexibly and accurately delivered to the desired location, achieving high control precision, minimal surgical trauma, and a safe and reliable procedure.

[0069] Reference Figures 4 to 6 As shown, in this embodiment, the center of the support plate 3 is further provided with a core rod mounting hole 3-3, and a core rod 5 (such as Figures 1 to 3 ), the tail of the core rod 5 is connected to the core rod push-pull rod 8, and the core rod 5 is also provided with a first wire outlet hole 5a and a second wire outlet hole 5b running through its front end face. The hook pull wire 7b is passed through the first wire outlet hole 5a, and the lock pull wire 7c is passed through the second wire outlet hole 5b. The core rod 5 can be used to adjust the wire outlet position, which is convenient for controlling the force direction of the pull wire, thereby ensuring the operational flexibility and labor-saving of the pull wire, and improving the accuracy of the closing operation of the closing clamp on the left atrial appendage. The movement of the core rod 5 is controlled by the core rod push-pull rod 8. It should be understood that the support tube 2 and the core rod push-pull rod 8 are both made of flexible materials, and can have a certain degree of flexibility as the sea wave tube 1a bends, so as to facilitate guidance and operation in the patient's body.

[0070] like Figures 14 to 16As shown, in this embodiment, preferably, two needle rods 6-2 are provided in a centrally symmetrical manner in the closed loop 6-1, and two oppositely arranged needle rod mounting holes 6-1a are provided on the outer side of the closed loop 6-1. The needle rod 6-2 is installed in the closed loop 6-1 along the direction of the puncture hook needle 6-2a through the corresponding needle rod mounting holes 6-1a. The above design can facilitate the assembly of the needle rod 6-2 on the one hand, and can utilize the needle rod 6-2 to improve the strength of both sides of the closed loop 6-1 on the other hand, so that the closed loop 6-1 can naturally bend and close at the weak area where the needle rod mounting hole 6-1a is located when closed, thereby improving the closing tightness of the closing clamp. The inner side of the closed loop 6-1 also has a hook thread hole 6-1b opposite the needle bar mounting hole 6-1a. The hook thread 7b is connected to one end of the corresponding needle bar 6-2 through the corresponding hook thread hole 6-1b, and is used to pull the needle bar 6-2 in a direction opposite to the puncture hook needle 6-2a so that the puncture hook needle 6-2a pierces the corresponding hook needle extrusion hole 6-1c. In the initial state, the needle tip of the puncture hook needle 6-2a is located in the hook needle extrusion hole 6-1c. By pulling the needle bar 6-2 to move, the needle tip of the puncture hook needle 6-2a is extended along the hook needle extrusion hole 6-1c, thereby being able to be combined with the tissue wall. Two hook pull wires 7b are also provided, each hook pull wire 7b controls a needle rod 6-2, making the pulling operation of the needle rod 6-2 simple and convenient, and being able to stably achieve the extension of the puncture hook needle 6-2a and firmly penetrate the tissue, ensuring the firmness of the connection between the closing ring 6-1 and the left atrial appendage tissue wall. The above-mentioned closing ring 6-1, needle rod 6-2 and puncture hook needle 6-2a are all made of metal materials, such as stainless steel, nickel titanium alloy and cobalt chromium alloy. In this embodiment, nickel titanium alloy is preferably used, which is a memory metal and can stably maintain the set shape after implantation, thereby further ensuring the closure stability and reliability of the left atrial appendage; of course, cobalt chromium alloy with good biocompatibility can also be used.

[0071] catch Figure 14 and Figure 15 As shown, in this embodiment, a plurality of support rod connection holes 6-1d are distributed on the inner side of the closing ring 6-1. The closing clamp opening and closing pull wires 7a pass through the corresponding telescopic support rods 4 and are connected to the corresponding support rod connection holes 6-1d. When the closing clamp opening and closing pull wires 7a are tightened, the ends of the telescopic support rods 4 can be inserted into the support rod connection holes 6-1d, so that the free ends of the telescopic support rods 4 are stably combined with the closing ring 6-1, thereby achieving stable expansion of the closing ring 6-1. After the closing ring 6-1 in the closed state and the telescopic support rods 4 in the retracted state are pushed out of the sleeve 1b, the direction of the closing ring 6-1 is controlled by pulling the two closing clamp opening and closing pull wires 7a located in the middle of the closing ring 6-1 in the closed state. For details, refer to Figure 3As shown, the end of the telescopic support rod 4 in the folded state is located in the middle position of the closed loop 6-1 in the closed state. At this time, the two closing clamp opening and closing pull wires 7a in the middle of the closing loop 6-1 are the shortest. By pulling the two closing clamp opening and closing pull wires 7a, the closing loop 6-1 can be flipped outward, thereby controlling the direction of the closing loop 6-1, making it convenient to adjust its relative position with the left atrial appendage opening by controlling the direction of the closing loop 6-1, thereby ensuring the implantation accuracy of the closing loop 6-1.

[0072] like Figure 14 and Figure 15 As shown, the above-mentioned interlocking assembly includes an upper lock buckle 6-3 and a lower lock buckle 6-4 that can be engaged with each other. The upper lock buckle 6-3 and the lower lock buckle 6-4 adopt a mechanical engagement structure. The upper lock buckle 6-3 has a lock hook facing the lower lock buckle 6-4. The upper lock buckle 6-3 and the lower lock buckle 6-4 are respectively arranged on the closed loop 6-1 and are located in the middle position of the corresponding needle rod 6-2; the upper lock buckle 6-3 and the lower lock buckle 6-4 are each connected to a lock buckle pull wire 7c, and the upper lock buckle 6-3 and the lower lock buckle 6-4 are pulled by the lock buckle pull wire 7c to deform and engage or disengage. When the lock cable 7c is pulled, the upper lock buckle 6-3 and the lower lock buckle 6-4 will produce different degrees of deformation on the closing ring 6-1, so that the lock hook on the upper lock buckle 6-3 is separated from the lower lock buckle 6-4. In the initial state, the upper lock buckle 6-3 and the lower lock buckle 6-4 can be in a disengaged state. When the closing ring 6-1 changes from the expanded state to the closed state, the upper lock buckle 6-3 and the lower lock buckle 6-4 are deformed by pulling the lock cable 7c, so that the lock hook on the upper lock buckle 6-3 passes over the lower lock buckle 6-4. After releasing the lock cable 7c, the upper lock buckle 6-3 and the lower lock buckle 6-4 are reset and buckled together. The interlocking assembly using the above-mentioned mechanical bite structure has a locking direction that is the closing deformation direction of the closing ring 6-1, so that the closing ring 6-1 is locked firmly and reliably when closed and is not easy to loosen. In addition, the pulling direction of the lock cable 7c on the upper and lower lock buckles is perpendicular to the closing ring, which can easily realize the buckling or disengagement control of the upper and lower lock buckles.

[0073] like Figures 7 to 13As shown, a left atrial appendage closure device of this embodiment has a telescopic support rod 4 with at least two mutually sleeved support tubes, and a locking assembly 4-7 is provided between two adjacent support tubes. The locking assembly 4-7 includes a plurality of locking blocks 4-7-1 distributed along the circumference, and each locking block 4-7-1 is embraced together by a hoop 4-7-2 to form an integral rotating body structure, and each locking block 4-7-1 can rotate around the hoop 4-7-2, and the hoop 4-7-2 is provided on the inner side of the support tube. The tail end of the support tube can be specifically provided with an annular groove 4-9 on the inner wall of the tail end of the inner support tube, and the hoop 4-7-2 can be clamped in the annular groove 4-9. In this way, the lock assembly 4-7 is restricted on the inner support tube, and the inner side of each locking block 4-7-1 has an inner conical surface 4-7-1a surrounding a conical hole. The end of the locking block 4-7-1 extending outward from the tail end of the support tube has a locking flange 4-7-1b extending outward. The inner side of the front end of the support tube located on the outside is provided with a locking flange 4-7-1b extending outward. The locking groove 4-8 can be matched with the locking flange 4-7-1b, and the end of each locking block 4-7-1 away from the locking flange 4-7-1b is connected together by an elastic ring 4-7-3, so that each locking block 4-7-1 has an elastic tendency to rotate around the hoop 4-7-2 to cause the locking flange 4-7-1b to expand outward; when each support tube is in a stretched state, the locking flange 4-7-1b is engaged in the corresponding locking groove 4-8; the telescopic support rod 4 also has There is an unlocking trigger rod 4-4 that can be pressed axially. The rear end of the unlocking trigger rod 4-4 has a pressing portion 4-4a, and the front end has a trigger portion 4-4b that matches the inner conical surface 4-7-1a of each locking block 4-7-1. By axially pressing the unlocking trigger rod 4-4, the trigger portion 4-4b is driven to extend into the conical hole surrounded by each locking block 4-7-1, prompting each locking block 4-7-1 to rotate around the hoop 4-7-2, causing the locking flange 4-7-1b to disengage and unlock from the locking slot 4-8. And as Figure 11 As shown, after each locking block 4-7-1 is unlocked, the unlocking trigger rod 4-4 can pass through the tapered hole formed by each locking block 4-7-1, so that the two adjacent support tubes can freely retract. In order to improve the telescopic ratio, this embodiment preferably adopts a three-section telescopic support rod 4, specifically including a first support tube 4-1, a second support tube 4-2 and a third support tube 4-3. The second support tube 4-2 is sleeved in the first support tube 4-1, and the third support tube 4-3 is sleeved in the second support tube 4-2. The tails of the second support tube 4-2 and the third support tube 4-3 are each provided with a set of locking components 4-7. Figure 8As shown, when the telescopic support rod 4 is in a stretched state, the trigger portion 4-4b of the unlocking trigger rod 4-4 extends to the locking assembly 4-7 at the tail end of the second support tube 4-2. When the pressing portion 4-4a is pressed to drive the unlocking trigger rod 4-4 to move upward, its trigger portion 4-4b extends into the tapered hole surrounded by each locking block 4-7-1 to achieve the unlocking of the first support tube 4-1 and the second support tube 4-2, so that the second support tube 4-2 and the third support tube 4-3 are contracted together. When the second support tube 4-2 is contracted to the shortest, the locking assembly 4-7 at the tail end of the third support tube 4-3 moves to a position close to the trigger portion 4-4b of the unlocking trigger rod 4-4. Pressing the unlocking trigger rod 4-4 again can achieve the unlocking of the second support tube 4-2 and the third support tube 4-3, and continue to contract the third support tube 4-3. The stretching, locking, unlocking and contraction of the telescopic support rod 4 are the key to realizing the transformation of the above-mentioned closed loop 6-1 from the initial closed state to the expanded state and then to the straight closed state. The locking component 4-7 locks the telescopic support rod 4 in the stretched state, which can ensure the stability of the stretched state of the telescopic support rod 4, and facilitates the use of the telescopic support rod 4 to support the closed loop 6-1 to keep it in a circular expanded state; at the same time, the locking component 4-7 can be unlocked by pressing the telescopic support rod 4 to contract the telescopic support rod 4, which facilitates the closing of the closed loop 6-1 into a "single" shape, and has good operational stability; in addition, the above-mentioned locking component 4-7 has a simple and compact structural design and can be installed in a telescopic support rod 4 with a small diameter; and the structural design is ingenious, and the multi-stage locking component can be unlocked by pressing the unlocking trigger rod 4-4, which is easy to operate.

[0074] like Figure 8 and Figure 11 As shown, in this embodiment, the unlocking trigger rod 4-4 is disposed in the support tube closest to the support plate 3 in the telescopic support rod 4, namely the first support tube 4-1. The tail end of the support tube is provided with a tail sleeve 4-5 and a return spring 4-6. The unlocking trigger rod 4-4 passes through the tail sleeve 4-5. The return spring 4-6 is sleeved on the unlocking trigger rod 4-4. One end of the return spring 4-6 acts on the tail sleeve 4-5, and the other end acts on the pressing portion 4-4a, which is used to drive the unlocking trigger rod 4-4 to reset after being pressed. The unlocking trigger rod 4-4 has good pressing feedback performance, further improving the convenience of surgical operation.

[0075] In order to facilitate the unlocking operation of the telescopic support rod 4, Figure 4 、 Figure 5 and Figure 18As shown, 90° guide holes 3-4 corresponding to the positions of the telescopic support rods 4 are further provided on the support plate 3, and the radial openings of the 90° guide holes 3-4 in the support plate 3 are opposite to the tail ends of the telescopic support rods 4 in the expanded state; an unlocking operating rod 9 is provided in the support tube 2, and the front end of the unlocking operating rod 9 has a flexible pressing section 9-1, which is passed through the corresponding 90° guide holes 3-4. The pressing movement of the unlocking operating rod 9 drives each flexible pressing section 9-1 to extend from the radial hole 3-1c of the 90° guide hole 3-4 and drives the corresponding unlocking trigger rod 4-4 to perform a press-unlocking action. The flexible pressing section 9-1 can move in the 90° guide hole 3-4, so that its end extends from the radial hole 3-1c of the 90° guide hole 3-4. When the telescopic support rod 4 switches from the retracted state to the expanded state, the radial hole 3-1c is opposite to the pressing part 4-4a at the tail of the telescopic support rod 4. By pressing the unlocking operating rod 9, the flexible pressing section 9-1 is used to trigger the pressing part 4-4a, thereby realizing the unlocking and contraction of the telescopic support rod 4, making it convenient to perform the unlocking operation of the telescopic support rod 4 from the outside, and having the advantages of simple structure and easy operation.

[0076] Reference Figure 6 As shown, short shafts 3-1a are respectively provided on both sides of the above-mentioned connecting seat 3-1, and a rotating shaft hole 4a-1 is provided on the rotating seat 4a for rotating cooperation with the short shaft 3-1a. The connecting seat 3-1 also has an axial hole 3-1b running through the upper and lower parts. When the telescopic support rod 4 is in the retracted state, the closing clamp opening and closing pull wire 7a passes through the axial hole 3-1b and enters the corresponding telescopic support rod 4; the axial hole 3-1b intersects with the 90° guide hole 3-4, and a wire groove 3-1d is provided on the upper side of the connecting seat 3-1 for connecting the axial hole 3-1b and the corresponding radial hole 3-1c. When the telescopic support rod 4 switches from the retracted state to the expanded state, the closing clamp opening and closing pull wire 7a passing through the axial hole 3-1b passes through the wire groove 3-1d and enters the radial hole 3-1c. To prevent the closing clamp opening and closing wire 7a from interfering with the extension of the flexible pressing section 9-1, a clearance groove can be provided at the end of the flexible pressing section 9-1. When the flexible pressing section 9-1 extends along the radial hole 3-1c, the closing clamp opening and closing wire 7a can enter the clearance groove, thereby avoiding obstruction of the flexible pressing section 9-1. In addition, the outer periphery of the support plate 3 also has a wire hole 3-2 opposite the aforementioned axial hole 3-1b, through which the closing clamp opening and closing wire 7a passes.

[0077] In this embodiment, the above-mentioned closing clamp opening and closing pull wire 7a, hook pull wire 7b and lock pull wire 7c, as well as the core rod push-pull rod 8 and the unlocking operating rod 9 all extend out of the tail end of the support tube 2. Accordingly, a pull wire handle can be set at the tail end of each closing clamp opening and closing pull wire 7a, hook pull wire 7b and lock pull wire 7c, and a corresponding push-pull handle can be set at the tail end of the core rod push-pull rod 8 and the unlocking operating rod 9. Each pull wire handle and push-pull handle can be set to a different color and / or shape to facilitate the distinction between the corresponding pull wire and operating rod during operation.

[0078] Figure 17 and Figure 19 The structure of the closure clip assembly in the expanded state is shown. To facilitate further understanding of the structural principle of the left atrial appendage closure device of the present invention, the following further describes the use process of the present invention in conjunction with the accompanying drawings:

[0079] Figure 1 This is the initial state of the LAA closure device. The telescopic support rod 4 is retracted, the closure clip assembly 6 is in its initial closed state (the interlocking assembly is not engaged), the telescopic support rod 4 and the closure clip assembly 6 are housed within the cannula 1b, and the support tube 2 is located within the hypotube 1a. During operation, the delivery catheter 1 follows the puncture device into the designated position, passing through the blood vessel and into the LAA opening.

[0080] Then, using the support tube 2 to push forward, the telescopic support rod 4 and the closing clamp assembly 6 are pushed out of the sleeve 1b. At this time, the two shortest closing clamp opening and closing cables 7a in the middle of the closing loop 6-1 tightly connect the two telescopic support rods 4 to the closing loop 6-1. The core rod push-pull rod 8 drives the core rod 5 forward. The pushing action of the end of the core rod 5 can change the direction of the closing clamp assembly 6 as a whole, so that the closing clamp assembly 6 and the core rod 5 remain substantially perpendicular. If the core rod 5 is not provided, the direction of the closing clamp assembly 6 can be adjusted by pulling the two shortest closing clamp opening and closing cables 7a.

[0081] Pull the other closing clamp opening and closing wires 7a except the shortest one, so that the ends of each telescopic support rod 4 are connected to the closed loop 6-1, and under the pulling force of the closing clamp opening and closing wires 7a, each telescopic support rod 4 is expanded outward, thereby expanding the closed loop 6-1 to Figure 17 The circular or nearly circular state shown.

[0082] Adjust the expanded closed loop 6-1 to the opening position of the left atrial appendage so that it fits with the tissue wall of the neck of the left atrial appendage; then pull the two hook pull lines 7b, so that the needle tip of the puncture hook needle 6-2a extends along the hook extrusion hole 6-1c and penetrates into the tissue wall to form a barb, and under the action of the barb of the puncture hook needle 6-2a, the closed loop 6-1 is connected to the tissue wall.

[0083] After that, push the unlocking operation rod 9 to unlock and retract each telescopic support rod 4, and pull and adjust the corresponding closing clamp opening and closing pull wire 7a and the lock buckle pull wire 7c to make the telescopic support rod 4 start to retract, and the closing ring 6-1 starts to drive the left atrial appendage to close together. Figure 15 When in the straight line position shown, the lock cable 7c is adjusted so that the upper and lower locks engage with each other. When the core rod 5 is installed, the telescopic support rod 4 can be retracted and folded, and then the telescopic support rod 4 can be withdrawn through the support tube 2. The core rod push-pull rod 8 and the core rod 5 can then be used to maintain the closed loop 6-1. The lock cable 7c is pulled to complete the final closure and interlocking of the closed loop 6-1.

[0084] Finally, all the pull wires are released and the other components are withdrawn along the delivery catheter 1. The closing clamp opening and closing pull wire 7a, hook pull wire 7b, and lock pull wire 7c are cut, leaving only the closing clamp assembly 6. The two hook pull wires 7b can be knotted and then cut. The knotted hook pull wires 7b can be used to maintain a certain tension on the needle shaft 6-2 to prevent the puncture hook 6-2a from retreating.

[0085] After the left atrial appendage is closed using the closing clip assembly 6, the blood supply to the left atrial appendage still exists and will not cause atrophy of the left atrial appendage. On the one hand, the fixation firmness of the puncture hook needle 6-2a will not be reduced due to atrophy of the left atrial appendage. On the other hand, it can ensure that other functions of the left atrial appendage are not affected.

[0086] The left atrial appendage closure device of the present invention utilizes a closure clip to close the left atrial appendage instead of the previous left atrial appendage occlusion technology, thereby ensuring the reliability and long-term effectiveness of the left atrial appendage closure. Specifically, the closure clip can be delivered to the opening of the left atrial appendage in a closed state using a delivery catheter, and is stretched at the left atrial appendage opening through the cooperation of a telescopic support rod and a control pull line. The puncture hook needle inside the closure clip is used to pierce the tissue wall of the left atrial appendage opening to achieve bonding, and finally the "one" closure of the closure clip is used to achieve closure of the left atrial appendage opening. Compared with the existing left atrial appendage occluder, the puncture hook needle on the periphery of the closure clip can penetrate the tissue in the radial direction, and the closure of the closure clip is used to drive the closure of the left atrial appendage opening, so that the connection between the closure clip and the left atrial appendage is more secure and not easy to fall off. At the same time, there is no problem of reduced reliability of the left atrial appendage sealing due to loosening or movement, thereby ensuring the long-term effectiveness of the left atrial appendage closure and reducing complications caused by falling off and unreliable sealing.

[0087] The above is a schematic description of the present invention and its embodiments, which is not restrictive. The drawings show only one embodiment of the present invention, and the actual structure is not limited thereto. Therefore, if a person skilled in the art is inspired by this and, without departing from the purpose of the present invention, designs structures and embodiments similar to this technical solution without creatively designing them, they shall fall within the scope of protection of the present invention.

Claims

1. A left atrial appendage closure device, characterized in that: include A delivery catheter (1) having a sleeve (1b) at its front end; A support tube (2) is inserted into the delivery conduit (1) and is used to be delivered to a designated position under the guidance of the delivery conduit (1); A support plate (3) is mounted on the front end of the support tube (2) and has a plurality of connecting seats (3-1) distributed circumferentially; A telescopic support rod (4), one end of which is mounted on a corresponding connecting seat (3-1) of the support disc (3) via a rotating seat (4a); each of the telescopic support rods (4) has a folded state converging toward the center and an expanded state radiating radially relative to the support disc (3); the folded state and the expanded state can be switched by rotating the telescopic support rod (4); each of the telescopic support rods (4) further comprises a locking assembly (4-7) for maintaining the telescopic support rod (4) in a stretched state and capable of triggering unlocking to retract the telescopic support rod (4); A closing clamp assembly (6) comprises a tubular closing ring (6-1), a needle rod (6-2) capable of being pulled is installed in the closing ring (6-1), a plurality of puncture hook needles (6-2a) are provided on the needle rod (6-2), a plurality of hook needle extrusion holes (6-1c) corresponding to the positions of the puncture hook needles (6-2a) are provided on the outer side of the closing ring (6-1), and the closing ring (6-1) also has an interlocking assembly for keeping the closing ring (6-1) in a "straight" closed state; The closed ring (6-1) in the closed state and the telescopic support rod (4) in the retracted state are housed in the sleeve (1b) and can be pushed forward out of the sleeve (1b) under the action of the support tube (2); The control pull wire (7) comprises a closing clamp opening and closing pull wire (7a), a hook pull wire (7b) and a lock pull wire (7c) located in the support tube (2); the front end of the closing clamp opening and closing pull wire (7a) passes through the corresponding telescopic support rod (4) and is connected to the closing ring (6-1); the control pull wire (7) is used to make the free end of the corresponding telescopic support rod (4) dock with the closing ring (6-1) by tightening the corresponding closing clamp opening and closing pull wire (7a), and to open the closing ring (6-1) when the telescopic support rod (4) is converted to the expanded state; the closing clamp opening and closing pull wire (7a) can also be used in the above-mentioned lock assembly After being unlocked, (4-7) cooperates with the contraction of the telescopic support rod (4) to control the closing of the closed loop (6-1) to the "I" closed state; the front end of the hook pull wire (7b) passes through the support disk (3) and is connected to the needle rod (6-2) in the closed loop (6-1), and is used to pull the needle rod (6-2) when the closed loop (6-1) is in the expanded state so that the puncture hook needle (6-2a) punctures the corresponding hook extrusion hole (6-1c); the front end of the lock pull wire (7c) is connected to the interlocking component on the closed loop (6-1), and is used to control the interlocking component to be engaged or disengaged through the lock pull wire (7c).

2. The left atrial appendage closure device according to claim 1, wherein: The delivery catheter (1) further comprises a hypotube (1a), and the sleeve (1b) is installed at the front end of the hypotube (1a).

3. The left atrial appendage closure device according to claim 1, wherein: The support disk (3) is also provided with a core rod mounting hole (3-3) at its center. A core rod (5) capable of axial movement is provided in the core rod mounting hole (3-3). The tail of the core rod (5) is connected to a core rod push-pull rod (8). The core rod (5) is also provided with a first wire outlet hole (5a) and a second wire outlet hole (5b) passing through its front end surface. The hook wire (7b) is passed through the first wire outlet hole (5a), and the lock wire (7c) is passed through the second wire outlet hole (5b).

4. The left atrial appendage closure device according to claim 1, wherein: Two needle rods (6-2) are centrally symmetrically provided in the closed loop (6-1), and the outer side of the closed loop (6-1) has two needle rod mounting holes (6-1a) arranged opposite to each other. The needle rod (6-2) is installed in the closed loop (6-1) through the corresponding needle rod mounting holes (6-1a) along the direction of the puncture hook needle (6-2a). The inner side of the closed loop (6-1) also has a hook wire hole (6-1b) opposite to the above-mentioned needle rod mounting holes (6-1a). The hook wire (7b) is connected to one end of the corresponding needle rod (6-2) through the corresponding hook wire hole (6-1b) and is used to pull the needle rod (6-2) to move in the direction opposite to the puncture hook needle (6-2a) so that the puncture hook needle (6-2a) pierces the corresponding hook extrusion hole (6-1c).

5. The left atrial appendage closure device according to claim 4, characterized in that: A plurality of support rod connection holes (6-1d) are also distributed on the inner side of the closing ring (6-1), and the closing clamp opening and closing pull wires (7a) pass through the corresponding telescopic support rods (4) and are connected to the corresponding support rod connection holes (6-1d); after the closing ring (6-1) in the closed state and the telescopic support rod (4) in the retracted state are pushed out of the sleeve (1b), the direction of the closing ring (6-1) is controlled by pulling the two closing clamp opening and closing pull wires (7a) located in the middle of the closing ring (6-1) in the closed state.

6. The left atrial appendage closure device according to claim 4, wherein: The interlocking assembly comprises an upper lock buckle (6-3) and a lower lock buckle (6-4) that can be engaged with each other. The upper lock buckle (6-3) and the lower lock buckle (6-4) are respectively arranged on the closed loop (6-1) and located in the middle of the corresponding needle rod (6-2). The upper lock buckle (6-3) and the lower lock buckle (6-4) are each connected to a lock buckle pull line (7c). The lock buckle pull line (7c) pulls the upper lock buckle (6-3) and the lower lock buckle (6-4) to deform and engage or disengage.

7. The left atrial appendage closure device according to any one of claims 1 to 6, characterized in that: The telescopic support rod (4) has at least two sections of mutually sleeved support tubes, and a locking assembly (4-7) is provided between two adjacent sections of the support tubes. The locking assembly (4-7) includes a plurality of locking blocks (4-7-1) distributed along the circumference, and each of the locking blocks (4-7-1) is held together by a hoop (4-7-2). The hoop (4-7-2) is provided at the tail end of the support tube located on the inner side, and the inner side of each locking block (4-7-1) has a closed The inner conical surface (4-7-1a) of the conical hole, the end of the locking block (4-7-1) extending outward from the rear end of the support tube has a locking flange (4-7-1b) extending outward, and the inner side of the front end of the support tube located on the outside is provided with a locking groove (4-8) capable of cooperating with the locking flange (4-7-1b), and the end of each locking block (4-7-1) away from the locking flange (4-7-1b) is connected to the inner side of the elastic ring (4-7-3) by being converged inward. The locking flange (4-7-1b) is elastically extended outward by rotating each locking block (4-7-1) around the hoop (4-7-2); when each support tube is in a stretched state, the locking flange (4-7-1b) is engaged in the corresponding locking slot (4-8); the telescopic support rod (4) further comprises an unlocking trigger rod (4-4) capable of axial pressing movement, and the tail end of the unlocking trigger rod (4-4) has a pressing force. The unlocking trigger rod (4-4) is axially pressed to drive the trigger portion (4-4b) to extend into the tapered hole surrounded by each locking block (4-7-1), thereby causing each locking block (4-7-1) to rotate around the hoop (4-7-2), thereby causing the locking flange (4-7-1b) to disengage and unlock from the locking slot (4-8).

8. The left atrial appendage closure device according to claim 7, characterized in that: The unlocking trigger rod (4-4) is arranged in a support tube closest to the support plate (3) in the telescopic support rod (4); a tail sleeve (4-5) and a return spring (4-6) are provided at the tail end of the support tube; the unlocking trigger rod (4-4) passes through the tail sleeve (4-5); the return spring (4-6) is sleeved on the unlocking trigger rod (4-4); one end of the return spring (4-6) acts on the tail sleeve (4-5) and the other end acts on the pressing portion (4-4a), and is used to drive the unlocking trigger rod (4-4) to return to its original position after being pressed.

9. The left atrial appendage closure device according to claim 8, characterized in that: The support plate (3) is further provided with 90° guide holes (3-4) corresponding to the positions of the telescopic support rods (4), and the radial openings of the 90° guide holes (3-4) of the support plate (3) are opposite to the tail ends of the telescopic support rods (4) in the unfolded state; an unlocking operation rod (9) is provided in the support tube (2), and the front end of the unlocking operation rod (9) has a flexible pressing section (9-1), which is inserted into the corresponding 90° guide holes (3-4). The pressing movement of the unlocking operation rod (9) drives each flexible pressing section (9-1) to extend from the radial hole (3-1c) of the 90° guide hole (3-4) and drives the corresponding unlocking trigger rod (4-4) to perform a press-unlocking action.

10. The left atrial appendage closure device according to claim 9, characterized in that: Short shafts (3-1a) are respectively provided on both sides of the connecting seat (3-1); a rotating shaft hole (4a-1) rotatably matched with the short shaft (3-1a) is provided on the rotating seat (4a); the connecting seat (3-1) also has an axial hole (3-1b) running through it from top to bottom; the axial hole (3-1b) intersects with the 90° guide hole (3-4); and a wire groove (3-1d) connecting the axial hole (3-1b) and the corresponding radial hole (3-1c) is provided on the upper side of the connecting seat (3-1); when the telescopic support rod (4) switches from a retracted state to an extended state, a closing clamp opening and closing pull wire (7a) passing through the axial hole (3-1b) passes through the wire groove (3-1d) and enters the radial hole (3-1c).

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