Formula for treating rhinitis and production process thereof

Abstract

The invention discloses a formula for treating rhinitis and a production process thereof, relates to the technical field of traditional Chinese medicines, and solves the technical problem that products in different forms cannot be prepared to meet different treatment requirements in the existing technical scheme. Comprising plant extracts and auxiliary additives, the plant extracts comprise fructus xanthii, flos magnoliae, herba asari, radix astragali, cynanchum otophyllum, rhizoma chuanxiong and centipeda minima, and the auxiliary additives comprise radix saposhnikoviae, agastache rugosus, honeysuckle flowers, wild chrysanthemum flowers, borneol, menthol, honey and beeswax. Various dosage forms can be prepared according to different rhinitis types and patient requirements; due to the flexible dosage form selection, the product can adapt to different clinical symptoms, and the use convenience and the treatment effect of a patient are remarkably improved; the main components in the formula all come from natural plant extracts and natural auxiliary additives, have low toxic and side effects, are mild to human bodies, and are suitable for long-term use.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine preparations, specifically a formula for treating rhinitis and a production process thereof. Background Art

[0002] The technical field involved in the invention is that rhinitis is an inflammation of the nasal mucosa and submucosal tissue, caused by various factors such as infection, allergy, and environmental irritation, and is mainly manifested by symptoms such as nasal congestion, runny nose, nasal itching, frequent sneezing, and decreased sense of smell. If not treated in time, rhinitis may cause complications such as sinusitis and otitis media, and even develop into chronic rhinitis. Plant extract preparations play an important role in the treatment of rhinitis, and their therapeutic effects are mainly exerted through mechanisms such as nasal dredging, anti-inflammatory and anti-allergic, antibacterial and antiviral, and immunity enhancement. For example, extracts of Xanthium sibiricum and Magnolia bud can clear the nasal passages and relieve nasal congestion; honeysuckle and forsythia have the functions of clearing heat and detoxifying, and antibacterial and antiviral; astragalus can enhance the body's immunity, thereby reducing the recurrence rate of rhinitis. In addition, the cooling effect of mint and borneol can also relieve nasal discomfort. Plant extract preparations usually act on multiple targets and help regulate the various causes and symptoms of rhinitis.

[0003] The use of botanical extracts in the treatment of rhinitis emphasizes not only effectiveness but also safety and naturalness. They have low toxicity and side effects, making them suitable for long-term use, particularly for children, the elderly, and those sensitive to chemical agents. Furthermore, botanical extracts can serve as management tools for chronic and allergic rhinitis, reducing the risk of recurrence and playing a significant role in improving patients' quality of life. In medical applications, botanical extracts offer comprehensive treatment through comprehensive anti-inflammatory and anti-allergic properties, promoting the development of more environmentally friendly and sustainable green healthcare. This combination of science and nature offers a new direction for rhinitis treatment while also reducing treatment costs socioeconomically, promising promising prospects for widespread adoption.

[0004] The existing technical solutions have the technical problem of being unable to prepare products in different forms to meet different treatment needs. Invention content

[0005] In response to the deficiencies of the prior art, the present invention provides a formula for treating rhinitis and a production process thereof, which solves the technical problem that the existing technical solutions cannot prepare products in different forms to meet different treatment needs.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions: a formula for treating rhinitis, comprising plant extracts and auxiliary additives, wherein the plant extracts include Xanthium sibiricum, Magnolia flos, Asarum sieboldii, Astragalus membranaceus, Astragalus root, Chuanxiong rhizome and Capsicum annuum, and the auxiliary additives include Saposhnikovia divaricata, Patchouli odorifera, Honeysuckle, Chrysanthemum indicum, borneol, menthol, honey and beeswax.

[0007] A rhinitis patch comprises plant extracts and auxiliary additives, which are prepared from raw materials including Xanthium sibiricum, Herba schizonepetae, Flos Magnoliae, Asarum, Flos Lonicerae, Flos Chrysanthemi Indici, Herba Phytophthorae, Herba Patchouli, Cortex Moutan, Rhizoma Coptidis, Radix Astragali, Herba Plantagoe, Fructus Forsythiae, and Saposhnikoviae. The raw materials are dried to control the moisture content below 10%, and then the raw materials are coarsely crushed. The pretreated raw materials are then mixed with purified water and boiled for extraction, filtered and the extract is collected, and the extract is vacuum concentrated to a solid consistency of 50%. Honey and beeswax are then added and mixed, and borneol and menthol are added and stirred until completely dissolved. Finally, the raw materials are coated, cut, dried, and packaged to prepare the patch.

[0008] A rhinitis aqueous solution comprises the following plant extracts and auxiliary additives: the raw materials are Xanthium sibiricum, Magnolia flos, Herba schizonepetae, Radix Bupleuri, Radix Angelicae Dahuricae, Radix Glycyrrhizae, and Asarum; the raw materials are removed of impurities and then washed with purified water; the washed plant raw materials are then temperature-controlled dried; the dried raw materials are pulverized to control the particle size to be between 40 and 60 meshes; a dilute ethanol solution is added to extract by a decoction method; the extract is filtered and concentrated by a vacuum concentration method; menthol is added to dissolve and stir at low temperature; the product is sterilized and filtered through a microfilter before filling to prepare the aqueous solution.

[0009] A rhinitis oil preparation comprises plant extracts and auxiliary additives, which are prepared from raw materials including Xanthium sibiricum, Magnolia flower, Chuanxiong, Asarum, Acorus calamus, Angelica dahurica, Herba schizonepetae, Saposhnikovia divaricata, Atractylodes macrocephala, Houttuynia cordata, Patchouli, and Mentha viride. The raw materials are washed with purified water, dried, and crushed, and purified plant oil is added. The raw materials are stirred at a temperature between 80° C. and 100° C. for 2-3 hours. The extract is then filtered through a filter, and peppermint oil, artificial musk, and alum are added. The raw materials are mixed and stirred at a temperature between 50° C. and 60° C. for 1 hour. The raw materials are finely filtered and then bottled to complete the preparation of the oil preparation.

[0010] A rhinitis ointment comprises the following plant extracts and auxiliary additives: astragalus, chuanxiong, xanthium sibiricum, angelica dahurica, mint, asarum, magnolia, tongcao, and borneol, which are rinsed with pure water, drained, and then dried at a low temperature and constant temperature in a drying oven, with the drying temperature controlled at 50-60°C. The dried medicinal materials are pulverized to control the particle size to be between 40 and 60 meshes, and the pulverized medicinal materials are added with pure water as an extraction solvent for decocting and extracting, and all extracts are collected. The extracts are cleared by collecting the extracts through multiple layers of gauze, and the filtered extracts are placed in a vacuum concentration device and allowed to stand and concentrate to form a viscous extract concentrate; the concentrated extract, honey, and vegetable oil are placed in a stirring pot, melted under low-temperature heating conditions, and continuously stirred; the prepared medicinal liquid concentrate is gradually added to the molten matrix, and the mixture is slowly stirred and mixed uniformly, with the temperature gradually increased during the stirring process to evaporate part of the solvent; the prepared ointment is left to cool naturally at room temperature and aseptically filled to prepare the ointment.

[0011] A rhinitis powder comprises plant extracts and auxiliary additives selected from astragalus, ligusticum chuanxiong, xanthium sibiricum, angelica dahurica, mint, asarum, magnolia, schizonepeta, soapberry, phellodendron and borneol. The raw materials are cleaned, cut into pieces, and dried in the shade, and then crushed and ground. The coarse powder is sieved and put into a mixer for uniform mixing. The mixed powder is dehumidified and then packaged to prepare the powder.

[0012] Beneficial effects

[0013] The present invention provides a formula for treating rhinitis and a production process thereof. The present invention combines plant extracts and auxiliary additives, and can prepare a variety of dosage forms according to different types of rhinitis and patient needs. This flexible dosage form selection enables the product to adapt to different clinical symptoms, significantly improving the patient's convenience of use and therapeutic effect. The main ingredients in the formula are all derived from natural plant extracts and natural auxiliary additives, with low toxic side effects, mild to the human body, and suitable for long-term use. Specially added auxiliary materials, such as borneol, menthol, and saposhnikovia divaricata, have the characteristics of cooling, clearing the orifices, and nourishing, which can not only directly relieve nasal symptoms, but also regulate the cause of rhinitis. The use of natural plant extracts is not only highly safe, but also reduces dependence on artificial chemical ingredients, and is a technological innovation that conforms to the concept of green environmental protection. The plant extract ingredients in the formula can provide multiple pharmacological effects through synergistic combination. The use of natural plant extracts as the main ingredients reduces dependence on expensive artificial drugs, has low cost, and is particularly suitable for primary medical promotion. DETAILED DESCRIPTION

[0014] In order to further illustrate the technical means and effects adopted by the present invention to achieve the predetermined purpose of the invention, the technical solutions in the embodiments of the present invention are clearly and completely described. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. The detailed description is as follows.

[0015] The present invention provides a technical solution: a formula for treating rhinitis, comprising plant extracts and auxiliary additives, wherein the plant extracts include Xanthium sibiricum, Magnolia bud, Asarum sieboldii, Astragalus membranaceus, Astragalus root, Chuanxiong rhizome and Caprifoliaceae; and the auxiliary additives include Saposhnikovia divaricata, Patchouli odorifera, Honeysuckle, Chrysanthemum indicum, Borneolum Syntheticum, menthol, honey and beeswax.

[0016] This embodiment is further configured as follows: the plant extracts and auxiliary additives are taken from raw materials such as Xanthium sibiricum, Herba schisandrae, Flos Magnoliae, Asarum, Flos Lonicerae, Flos Chrysanthemi Indici, Herba Plantaine, Herba Patchouli, Cortex Moutan, Rhizoma Coptidis, Radix Astragali, Semen Plantagoe, Fructus Forsythiae, and Saposhnikoviae, and the moisture content is controlled below 10% by drying, and then the raw materials are coarsely crushed, and then the pretreated raw materials are mixed with purified water for decoction and extraction, filtered and collected, and the extract is vacuum concentrated and extracted to a solid consistency of 50%, and then honey and beeswax are added and mixed, and borneol and menthol are added and stirred until completely dissolved, and finally coated, cut, dried and packaged to prepare a patch.

[0017] This embodiment is further configured as follows: the plant extracts and auxiliary additives are made from raw materials such as Xanthium sibiricum, Magnolia flos, Schisandra chinensis, Bupleurum chinense, Angelica dahurica, Licorice root, and Asarum sieboldii, which are washed with pure water after removing impurities, and then the washed plant raw materials are temperature-controlled and dried, and the dried raw materials are crushed to control the particle size between 40-60 meshes, and a dilute ethanol solution is added to extract using a water decoction method, the extract is filtered and concentrated using a vacuum concentration method, and menthol is added to dissolve and stir at low temperature, and the product is sterilized and filtered through a microfilter before filling to prepare an aqueous solution.

[0018] This embodiment is further configured as follows: the plant extracts and auxiliary additives are made from raw materials such as Xanthium sibiricum, Magnolia flower, Chuanxiong, Asarum, Acorus calamus, Angelica dahurica, Herba Capillaris, Saposhnikovia divaricata, Atractylodes macrocephala, Houttuynia cordata, Patchouli, and Mentha viride, which are washed with pure water and then dried and crushed, and pure vegetable oil is added, and stirred at 80℃-100℃ for 2-3 hours, and then the extract is filtered through a filter, and then peppermint oil, artificial musk and alum are added, and mixed and stirred at 50℃-60℃ for 1 hour, and then filled after fine filtration to complete the preparation of the oil.

[0019] This embodiment is further configured as follows: the plant extracts and auxiliary additives are astragalus, Chuanxiong, Xanthium sibiricum, Angelica dahurica, mint, asarum, magnolia, tongcao, and borneol, which are rinsed with pure water, drained, and then dried at a low temperature and constant temperature in a drying oven, the drying temperature is controlled at 50-60°C, the dried medicinal materials are crushed, and the particle size is controlled between 40-60 meshes, the crushed medicinal materials are added to pure water as an extraction solvent, and water decocted and extracted, all the extracts are collected, and the extracts are collected through multiple layers of gauze to clarify the extracts, the filtered extracts are placed in a vacuum concentration device, and allowed to stand and concentrate to form a viscous extract concentrate; the concentrated extract, honey and vegetable oil are placed in a stirring pot, melted under low temperature heating conditions, and constantly stirred, the prepared medicinal liquid concentrate is gradually added to the molten matrix, slowly stirred and mixed evenly, and the temperature is gradually increased during the stirring process to evaporate part of the solvent; the prepared ointment is placed to room temperature for natural cooling and aseptically filled to prepare the ointment.

[0020] This embodiment is further configured as follows: the plant extracts and auxiliary additives are astragalus, Chuanxiong, Xanthium sibiricum, Angelica dahurica, mint, asarum, magnolia, schizonepeta, soapberry, phellodendron and borneol; the raw materials are washed, cut into pieces and dried in the shade, then crushed and ground; the coarse powder is sieved and put into a mixer for uniform mixing, the mixed powder is dehumidified and packaged to prepare a powder.

[0021] Example 1: Patch for treating rhinitis

[0022] Recipe Ingredients

[0023] Plant extracts: Xanthium sibiricum, Herba schizonepetae, Magnolia bud, Asarum sieboldii, Honeysuckle, Chrysanthemum indicum, Herba sylvestris, Patchouli, Cortex Moutan, Coptis chinensis, Astragalus membranaceus, Plantago asiatica, Forsythia suspensa, Saposhnikovia divaricata

[0024] Excipients: honey, beeswax, borneol, menthol

[0025] After cleaning, plant raw materials such as Xanthium sibiricum are dried to control the moisture content below 10%, and then crushed into a coarse powder. The coarse powder raw materials are placed in an extraction tank and decocted with 10 times the amount of purified water. Each decocting is done for 2 hours, and the extraction is repeated twice. The combined extracts are filtered to remove the residue. The extracted liquid is concentrated to a solid concentration of 50% using a vacuum concentration method to form a highly viscous extract. Honey and beeswax are added to the concentrated extract in sequence and stirred at low temperature to dissolve. Borneol and menthol are then added and stirred again. The mixed liquid is evenly applied on non-woven fabric or medical patch to form tablets with uniform coating and thickness. After drying, the mixture is cut into a patch size suitable for application and the finished product is sealed and packaged.

[0026] The patch is applied to the outside of the nasal cavity or specific acupuncture points to slowly release the drug, exerting anti-inflammatory, antibacterial, orifice-opening and cooling effects. It is suitable for the long-term treatment of chronic rhinitis or allergic rhinitis.

[0027] Example 2: Aqueous preparation for treating rhinitis

[0028] Recipe Ingredients

[0029] Plant extracts: Xanthium sibiricum, Magnolia officinalis, Herba Eupatorii, Bupleurum chinense, Angelica dahurica, Licorice, Asarum

[0030] Excipients: Menthol, Borneol

[0031] After cleaning the raw plant material, dry it at a controlled temperature of 50-60°C, then crush it to a 40-60 mesh fineness. Heat and extract the crushed material with a 10-fold dilute ethanol solution twice, each extraction lasting 2 hours. Filter the extract and take the clarified portion. Concentrate the extracted liquid to the desired concentration using a vacuum concentrator. Add menthol and borneol to the concentrate and stir until completely dissolved. Stir the liquid at low temperature, then pass it through a microfilter to remove impurities and sterilize it. Dispense the treated liquid into nasal drop bottles and seal them.

[0032] The prepared aqueous solution can be used as nasal drops for rhinitis, which can effectively relieve symptoms such as nasal congestion, runny nose, and mucosal congestion. It is suitable for patients with acute rhinitis or allergic rhinitis.

[0033] Example 3: Oil for treating rhinitis

[0034] Recipe Ingredients

[0035] Plant extracts: Xanthium sibiricum, Magnolia flower, Chuanxiong, Asarum, Acorus calamus, Angelica dahurica, and Herba schizonepetae

[0036] Excipients: alum, peppermint oil, artificial musk

[0037] After washing the raw plant material, dry and crush it to a powder size of 40-60 mesh. The crushed medicinal material is mixed with vegetable oil in a ratio of 1:8, placed in an extraction pot, and stirred and extracted at 80°C-100°C for 2-3 hours. The active ingredients in the medicinal material are recovered, and the oil extract is collected after filtering. Peppermint oil and artificial musk are added to the extracted medicinal oil, along with an appropriate amount of alum. Continue stirring and mixing at 50°C-60°C for 1 hour to ensure uniformity. The medicinal solution is filtered through a 300-mesh fine filter, filled into small bottles, and sealed to complete the product.

[0038] The finished oil can be dripped into the nose or applied inside the nasal cavity to lubricate the mucosa, fight inflammation and kill bacteria, and relieve allergic symptoms. It is especially suitable for patients with seasonal rhinitis and dry environments.

[0039] Example 4: Ointment for treating rhinitis

[0040] Recipe Ingredients

[0041] Plant extracts: Astragalus, Chuanxiong, Xanthium sibiricum, Angelica dahurica, Peppermint, Asarum, Magnolia, Tongcao

[0042] Accessories: honey, vegetable oil

[0043] The plant material is cleaned, dried, and crushed. It is then boiled and extracted three times with purified water. The extract is filtered and concentrated in a vacuum concentrator to obtain a thick extract. Honey and vegetable oil are mixed and heated until completely melted. The concentrated extract is then slowly added and mixed at low temperature until a paste is formed. After the paste cools to room temperature, it is dispensed into ointment tubes and sealed.

[0044] Ointment is suitable for use as a topical product to relieve inflammatory reactions around the outside of the nose and to have the effects of continuous moisturizing and clearing the orifices.

[0045] Example 5: Powder for treating rhinitis

[0046] Recipe Ingredients

[0047] Plant extracts: Astragalus, Chuanxiong, Xanthium sibiricum, Angelica dahurica, Menthol, Asarum, Magnolia, Schizonepeta tenuifolia, Gleditsia sinensis, Phellodendron amurense, Borneol

[0048] After washing and drying, crush the plant material to a 200-mesh fine powder. Crush the borneol to 300-mesh for later use. Mix the powders according to the formula ratio and stir at low speed in a mixer for 30 minutes to ensure uniformity. If necessary, add a flow aid to improve flowability. After dehumidifying the mixed powder, divide it into small, sealed bags or bottles.

[0049] The powder is highly portable and can be taken directly or used as an external powder, meeting various rhinitis treatment needs.

[0050] It should be noted that, in this document, relational terms such as first and second, etc. are merely used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations.

[0051] The above description is merely a preferred embodiment of the present invention and does not constitute any form of limitation to the present invention. Although the present invention has been disclosed as a preferred embodiment, it is not intended to limit the present invention. Any person skilled in the art can make some changes or modifications to equivalent embodiments using the technical contents disclosed above without departing from the scope of the technical solution of the present invention. However, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A formulation for treating rhinitis, characterized in that: The invention comprises plant extracts and auxiliary additives. The plant extracts comprise Xanthium sibiricum, Flos Magnoliae, Asarum, Radix Astragali, Radix Astragali, Rhizoma Chuanxiong and Herba Eupatorii; and the auxiliary additives comprise Saposhnikovia divaricata, Patchouli odorifera, Flos Lonicerae, Flos Chrysanthemi Indici, borneol, menthol, honey and beeswax.

2. The production process of a formula for treating rhinitis according to claim 1, characterized in that The plant extracts and auxiliary additives are made from raw materials such as Xanthium sibiricum, Herba Ligustici Abutilonis, Flos Magnoliae, Asarum, Flos Lonicerae, Flos Chrysanthemi Indici, Herba Plantaine, Herba Patchouli, Cortex Moutan, Rhizoma Coptidis, Radix Astragali, Semen Plantagoe, Fructus Forsythiae, and Saposhnikovia Divaricata. The moisture content is controlled below 10% and the raw materials are dried. The raw materials are then coarsely crushed. The pretreated raw materials are then mixed with purified water and boiled for extraction. The extract is filtered and collected. The extract is vacuum concentrated and extracted to a solid consistency of 50%. Honey and beeswax are then added and mixed. Borneol and menthol are added and stirred until completely dissolved. Finally, the patches are coated, cut, dried and packaged to prepare the patches.

3. The production process of a formula for treating rhinitis according to claim 1, characterized in that The plant extracts and auxiliary additives are made from raw materials such as Xanthium sibiricum, Magnolia officinalis, Schisandra chinensis, Bupleurum chinense, Angelica dahurica, Licorice root and Asarum sieboldii. After removing impurities, the washed plant raw materials are washed with purified water, and then temperature-controlled drying is performed. The dried raw materials are crushed to control the particle size between 40-60 meshes, and a dilute ethanol solution is added to extract using a water decoction method. The extract is filtered and concentrated using a vacuum concentration method. Menthol is added to dissolve and stir at low temperature. The product is sterilized and filtered through a microfilter before filling to prepare an aqueous solution.

4. The production process of a formula for treating rhinitis according to claim 1, characterized in that The plant extracts and auxiliary additives are made from raw materials such as Xanthium sibiricum, Magnolia flower, Chuanxiong, Asarum, Acorus calamus, Angelica dahurica, Herba Capillaris, Saposhnikovia divaricata, Atractylodes macrocephala, Houttuynia cordata, Patchouli, and Mentha viride. After washing with pure water, they are dried and crushed. Pure vegetable oil is added and stirred at 80℃-100℃ for 2-3 hours. The extract is then filtered through a filter. Peppermint oil, artificial musk, and alum are then added and mixed and stirred at 50℃-60℃ for 1 hour. After fine filtration, the mixture is bottled to complete the preparation of the oil.

5. The production process of a formula for treating rhinitis according to claim 1, characterized in that The plant extracts and auxiliary additives are astragalus, chuanxiong, xanthium sibiricum, angelica dahurica, mint, asarum, magnolia, tongcao, and borneol, which are rinsed with pure water and drained, and then dried at a low temperature and constant temperature in a drying oven, and the drying temperature is controlled at 50-60°C. The dried medicinal materials are crushed and the particle size is controlled between 40-60 meshes. The crushed medicinal materials are added with pure water as an extraction solvent and decocted and extracted. All the extracts are collected and clarified through multiple layers of gauze. The filtered extract is placed in a vacuum concentration device and allowed to stand and concentrate to form a viscous extract concentrate; the concentrated extract, honey and vegetable oil are placed in a stirring pot and melted under low temperature heating conditions while stirring continuously. The prepared medicinal liquid concentrate is gradually added to the molten matrix and slowly stirred to mix evenly. The temperature is gradually increased during the stirring process to evaporate part of the solvent; the prepared ointment is placed to room temperature for natural cooling and aseptic filling to prepare the ointment.

6. The production process of a formula for treating rhinitis according to claim 1, characterized in that The plant extracts and auxiliary additives are astragalus, chuanxiong, xanthium sibiricum, angelica dahurica, mint, asarum, magnolia, schizonepeta, soapberry, phellodendron and borneol; the raw materials are washed, cut into pieces and dried in the shade, then crushed and ground; the coarse powder is sieved and put into a mixer for uniform mixing, the mixed powder is dehumidified and packaged to prepare powder.