Preparation method of composition containing enhanced anti-hair loss component and deposited on scalp, anti-hair loss and hair growth composition and shampoo
By adding cationic raw materials and anti-hair loss active ingredients to shampoo, a viscous liquid is formed and exists in a flocculent state, which solves the problem of insufficient deposition of anti-hair loss ingredients in shampoo and achieves improved anti-hair loss and anti-dandruff effects.
Patent Information
- Application Number
- CN202510667909.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-22
- Publication Date
- 2025-09-23
AI Technical Summary
The anti-hair loss ingredients in shampoo are easily washed away by water and are difficult to deposit on the scalp, resulting in slow effects.
Adding cationic raw materials and anti-hair loss active ingredients into shampoo forms a viscous liquid that exists in a flocculent state, enhancing deposition on the scalp.
It improves the anti-dandruff effect, reduces the residue of amino acid surfactants and the use of preservatives, reduces irritation, and enhances the anti-dandruff effect.
Smart Images
Figure CN120678691A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the fields of anti-hair loss technology and shampoo composition technology, and in particular to a method for preparing a composition containing an enhanced anti-hair loss component and deposited on the scalp, an anti-hair loss and hair growth composition, and a shampoo. Background Art
[0002] The anti-hair loss ingredients in shampoo are easily washed away by water along with anionic surfactants after use, and rarely deposit on the scalp, so shampoo products are slow to take effect.
[0003] Research in related art shows that the deposition of anti-dandruff agents can be enhanced through technical means, thereby improving the anti-dandruff effect of shampoo. Summary of the Invention
[0004] The embodiments of the present application provide a method for preparing a composition containing an enhanced anti-hair loss ingredient that is deposited on the scalp, wherein cationic raw materials and an effective anti-hair loss ingredient are mixed into shampoo to achieve enhanced anti-hair loss and deposition on the scalp.
[0005] The embodiments of this application adopt the following technical solutions:
[0006] In a first aspect, embodiments of the present application provide a method for preparing a composition containing an enhanced anti-hair loss ingredient that is deposited on the scalp, wherein the method comprises:
[0007] S1, prepare cationic raw materials, dissolve and mix to form colloid;
[0008] S2, mixing the anti-hair loss active ingredient into the colloid to form a viscous liquid;
[0009] S3, adding the viscous liquid to shampoo, so that the cationic flocculent exists in the shampoo.
[0010] In some embodiments, the step S2 specifically includes: evenly distributing the anti-hair loss active ingredient in the cationic colloid to form a viscous liquid.
[0011] In some embodiments, step S3 further comprises: adding the viscous liquid to shampoo to reduce the residue of amino acid surfactant on the scalp while reducing the amount of preservatives used in the formula.
[0012] In some embodiments, the amino acid surfactant includes at least one or more combinations of sodium lauryl glycol carboxylate and sodium methyl cocoyl taurate.
[0013] In some embodiments, step S1 further includes:
[0014] The cationic raw materials are fully dissolved and mixed in advance; the cationic raw materials are dissolved in water and the concentration is about 5%.
[0015] In some embodiments, step S2 specifically includes:
[0016] The anti-hair loss effective ingredients are mixed in sequence and uniformly, wherein the anti-hair loss effective ingredients include Platycladus orientalis extract and sandalwood extract, and the total amount of the anti-hair loss effective ingredients is about 50% of the cationic colloid.
[0017] In some embodiments, the anti-hair loss ingredient flocculent is a mixture of a cationic colloid and an anti-hair loss ingredient, and its mass accounts for about 10% of the shampoo.
[0018] In a second aspect, the embodiments of the present application further provide an anti-hair loss and hair growth composition comprising an enhanced anti-hair loss ingredient and deposited on the scalp, prepared by the preparation method described in the first aspect.
[0019] In a third aspect, the embodiments of the present application further provide a shampoo comprising a composition that enhances anti-hair loss ingredients and is deposited on the scalp, prepared by the preparation method described in the first aspect.
[0020] At least one of the above technical solutions adopted in the embodiments of the present application can achieve the following beneficial effects: first, cationic raw materials are prepared, dissolved and mixed to form a colloid. Then, the anti-hair loss active ingredient is mixed into the colloid to form a viscous liquid. Finally, the viscous liquid is added to shampoo so that the cationic flocculent exists in the shampoo. In the final stage of shampoo production, it is added to the formula so that it exists in the shampoo in the form of cationic flocculent and can exist stably. In this way, after using the shampoo, the anti-hair loss active ingredient can be adsorbed on the hair roots and scalp along with the cations, thereby preventing hair loss and enhancing the anti-dandruff effect. At the same time, adding the viscous liquid to the shampoo can reduce the irritation of the shampoo and obtain a better product state. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] The drawings described herein are used to provide a further understanding of the present application and constitute a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation on the present application. In the drawings:
[0022] Figure 1 Schematic diagram of the process for preparing a composition containing an enhanced anti-hair loss ingredient that is deposited on the scalp in an embodiment of the present application;
[0023] Figure 2 Schematic diagram of the implementation principle of the method for preparing the composition containing the enhanced anti-hair loss ingredient and deposited on the scalp in the embodiment of the present application;
[0024] Figure 3 This is a multi-point Raman scanning spectrum result diagram of the entire skin layer in the embodiment of this application;
[0025] Figure 4 This is the Raman pseudo-color result image reconstructed after large-scale scanning in the embodiment of this application (blank group);
[0026] Figure 5 This is the Raman pseudo-color result image reconstructed after large-scale scanning in the embodiment of this application (control group 1);
[0027] Figure 6 This is the Raman pseudo-color result image reconstructed after large-scale scanning in the embodiment of this application (control group 2);
[0028] Figure 7 This is the detection result of the confocal Raman spectrometer in the examples of this application. DETAILED DESCRIPTION
[0029] To make the purpose, technical solutions, and advantages of this application more clear, the technical solutions of this application will be clearly and completely described below in conjunction with the specific embodiments of this application and the corresponding drawings. Obviously, the embodiments described are only part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.
[0030] The following describes in detail the technical solutions provided by various embodiments of the present application in conjunction with the accompanying drawings.
[0031] The inclusion of cationic ingredients in shampoo products, which enhance hair loss prevention and deposit on the scalp, is due to their ability to absorb onto the hair surface, improving the feel of hair after shampooing. However, the challenge lies in selecting the cationic ingredients, the active ingredients for hair loss prevention, and how to incorporate them into the shampoo.
[0032] The present application provides a method for preparing a composition containing an enhanced anti-hair loss component that is deposited on the scalp, such as Figure 1 , a schematic flow chart of a method for preparing a composition containing an enhanced anti-hair loss component and deposited on the scalp according to an embodiment of the present application is provided. The method comprises at least the following steps S1 to S3:
[0033] Step S1, prepare cationic raw materials, dissolve and mix them to form a colloid.
[0034] In the preparation method in the examples of the present application, there is no specific limitation on the preparation time, environmental conditions, and preparation equipment, as long as the key steps in the examples of the present application are met.
[0035] like Figure 2 As shown, after the cationic raw materials are prepared, the colloid is formed by dissolving and mixing. It can be understood that the colloid can be pre-formed in a variety of ways, which are not specifically limited in the embodiments of the present application.
[0036] Step S2: mixing the anti-hair loss active ingredient into the colloid to form a viscous liquid.
[0037] In addition to preparing cationic raw materials, it is also necessary to mix the anti-hair loss active ingredients into the colloid and consider forming a viscous liquid. After the cationic raw materials are dissolved and mixed to form a colloid, the anti-hair loss active ingredients are wrapped therein.
[0038] like Figure 2 As shown, a microemulsification method is specifically used to evenly distribute the anti-hair loss ingredients in the cationic colloid.
[0039] Step S3, adding the viscous liquid into shampoo, so that the cationic flocculent exists in the shampoo.
[0040] In the final stage or at a certain stage of shampoo production, it is added to the formula so that it exists in the shampoo in the form of cationic flocculent and can exist stably. Figure 2 As shown, the flocculent can exist stably at high temperature without stratification and can be quickly dispersed in shampoo without aggregation.
[0041] In this way, after using shampoo, the anti-hair loss ingredients can be absorbed on the hair roots and scalp along with cations, thereby enhancing the effect.
[0042] In one embodiment of the present application, the cationic raw material at least includes: a high molecular weight polymer of a polyquaternary ammonium salt.
[0043] The selection of cationic raw materials includes but is not limited to high molecular polymers, such as polyquaternary ammonium salts.
[0044] In one embodiment of the present application, the step S2 specifically includes: evenly distributing the anti-hair loss active ingredient in the cationic colloid to form a viscous liquid.
[0045] In order to obtain better results, it is necessary to evenly distribute the anti-hair loss active ingredients in the cationic colloid. It is understood that even distribution can be achieved through processing and production machinery, and finally form a viscous liquid.
[0046] In one embodiment of the present application, step S3 further includes: adding the viscous liquid to shampoo to reduce the residue of amino acid surfactant on the scalp while reducing the amount of preservatives used in the formula.
[0047] To achieve a synergistic effect with other ingredients in the shampoo, the viscous liquid, when added to the shampoo, can reduce the amount of amino acid surfactant residue on the scalp and reduce the amount of preservatives used in the formula. Specifically, the viscous liquid, when added to the shampoo, can reduce the amount of amino acid surfactant residue on the scalp, thereby reducing the irritation caused by the cleansing ingredients (related to dandruff and itching, etc.). At the same time, its certain bactericidal ability can reduce the amount of preservatives used in the formula (preservatives are generally also a source of irritation).
[0048] In one embodiment of the present application, the amino acid surfactant includes at least one or more combinations of sodium lauryl glycol carboxylate and sodium methyl cocoyl taurate.
[0049] Preferably, the amino acid surfactant is sodium lauryl glycol carboxylate.
[0050] Preferably, the amino acid surfactant is sodium methyl cocoyl taurate.
[0051] Preferably, the amino acid surfactant is a combination of the two in a certain mass ratio.
[0052] In one embodiment of the present application, the step S1 further includes: fully dissolving and mixing the cationic raw materials in advance, wherein the cationic raw materials are dissolved in water and the concentration is about 5%.
[0053] Cationic raw materials are dissolved in water without special solvents, and the optimal concentration of cationic raw materials is about 5%-7%.
[0054] In one embodiment of the present application, step S2 specifically includes: mixing the anti-hair loss effective ingredients in sequence, wherein the anti-hair loss effective ingredients include Platycladus orientalis extract and sandalwood extract, and the total amount of the anti-hair loss effective ingredients is about 50% of the cationic colloid.
[0055] The anti-hair loss ingredients are Platycladus orientalis extract and sandalwood extract, and the total amount of the anti-hair loss ingredients is about 50%-60% of the cationic colloid.
[0056] Alternatively, sandalwood extract may be added preferentially.
[0057] In one embodiment of the present application, the anti-hair loss ingredient flocculent is a cationic colloid and an anti-hair loss ingredient. It is understood that other major ingredients in shampoo include, but are not limited to, fatty acyl methyl taurates, fatty acyl isethionates, fatty acylopropyl betaines, N-fatty acyl amino acid salts, modified guar gum, fatty acid glycol diesters, etc. The anti-hair loss ingredient flocculent is a mixture of cationic colloids and anti-hair loss ingredients, accounting for approximately 10%-15% of the shampoo.
[0058] Table 1
[0059]
[0060] Table 1 is a schematic diagram of the test grouping. Specifically, 30 minutes after sample loading, 500 μL of deionized water was taken to clean the surface of the model for a total of 10 times. After being left for another 24 hours, the model was collected.
[0061] Table 2
[0062]
[0063] Table 2 shows the total integrated intensity results (unit: 1002 cm -1 )
[0064] Specifically, when using the t-test method for statistical analysis in Table 2:
[0065] Compared with the blank control group, significance is indicated by *, P-value < 0.05 is indicated by *, and P-value < 0.01 is indicated by **.
[0066] Compared with the target extract dilution group, significance is indicated by #, P-value < 0.05 is indicated by #, and P-value < 0.01 is indicated by ##.
[0067] like Figure 3 The figure shows the results of multi-point Raman scanning spectra of the entire skin layer, including a blank control group, a target suspension, and a target extract dilution. Among them, a suspension is a heterogeneous dispersion system formed by insoluble solid drug particles dispersed in a liquid medium. It needs to be shaken by physical oscillation before use and is commonly used in the fields of medicine and chemical industry. Among them, the dilution of the extract refers to a low-concentration solution obtained by mixing the extract with a solvent (usually water) in a certain proportion. An extract is usually a solution containing a specific component, which is used to extract a certain substance in experiments or industrial production.
[0068] like Figure 4-6 As shown, the Raman pseudo-color result image reconstructed after large-scale scanning, the stratum corneum and epidermal living cell layer, Figure 4 As blank control, Figure 5 For suspension, such as Figure 6 Shown are extract dilutions.
[0069] like Figure 7 The results of confocal Raman spectrometer detection are shown below:
[0070] (1) Compared with the blank control group, the sample suspension acted on the skin for 24 hours at 1002 cm -1 The total integrated intensity increased significantly below the peak, indicating that the sample Platycladus orientalis suspension had residues in the bark.
[0071] (2) Compared with the blank control group, the dilution of the sample extract acted on the skin for 24 hours at 1002 cm -1 The total integrated intensity increased significantly below the peak, indicating that the sample extract diluent remained in the skin.
[0072] (3) Compared with the extract dilution group, the sample suspension had a higher sensitivity at 1002 cm after 24 h of application to the skin. -1 Under the peak, the total integrated intensity in the bark was significantly higher than that in the diluted Platycladus orientalis extract, indicating that more residues remained in the bark of the suspension.
[0073] The present invention provides an anti-hair loss and hair growth composition prepared by the above-mentioned preparation method, which contains an enhanced anti-hair loss component and is deposited on the scalp. The anti-hair loss and hair growth composition can be used in shampoo and lotion.
[0074] In an embodiment of the present application, a shampoo containing a composition that enhances anti-hair loss and is deposited on the scalp is provided, which is prepared by the preparation method.
[0075] The foregoing is merely an embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various changes and variations. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present application should all be included within the scope of the claims of the present application.
Claims
1. A method for preparing a composition containing an enhanced anti-hair loss ingredient that is deposited on the scalp, wherein: The method comprises: S1, prepare cationic raw materials, dissolve and mix to form colloid; S2, mixing the anti-hair loss active ingredient into the colloid to form a viscous liquid; S3, adding the viscous liquid to shampoo, so that the cationic flocculent exists in the shampoo.
2. The method according to claim 1, wherein: The cationic raw materials at least include: high molecular polymers of polyquaternary ammonium salts.
3. The method according to claim 1, wherein: The step S2 specifically includes: evenly distributing the anti-hair loss active ingredient in the cationic colloid to form a viscous liquid.
4. The method according to claim 1, wherein: The step S3 further comprises: adding the viscous liquid to shampoo to reduce the residue of amino acid surfactant on the scalp while reducing the amount of preservatives used in the formula.
5. The method according to claim 4, wherein: The amino acid surfactant at least includes: any one or more combinations of sodium lauryl glycol carboxylate and sodium methyl cocoyl taurate.
6. The method of claim 1, wherein: The step S1 further includes: The cationic raw materials are fully dissolved and mixed in advance; the cationic raw materials are dissolved in water and the concentration is about 5%.
7. The method of claim 1, wherein: The step S2 specifically includes: The anti-hair loss effective ingredients are mixed in sequence and uniformly, wherein the anti-hair loss effective ingredients include Platycladus orientalis extract and sandalwood extract, and the total amount of the anti-hair loss effective ingredients is about 50% of the cationic colloid.
8. The method of claim 1, wherein: The anti-hair loss functional ingredient flocculent gel is a mixture of cationic colloid and anti-hair loss functional ingredient, and its mass accounts for about 10% of the shampoo.
9. An anti-hair loss and hair growth composition prepared by the method according to any one of claims 1 to 8, comprising an enhanced anti-hair loss component and deposited on the scalp.
10. A shampoo comprising a composition that is deposited on the scalp and contains an enhanced anti-hair loss ingredient, prepared by the method according to any one of claims 1 to 8.