Ablation catheter, ablation system and method for manufacturing ablation catheter

Abstract

The invention relates to the technical field of tissue ablation, and discloses an ablation catheter, an ablation system and a method for manufacturing the ablation catheter. The ablation catheter comprises a catheter body and a functional assembly, the catheter body is provided with a first guide wire channel penetrating through the catheter body, and the length direction of the first guide wire channel extends in the length direction of the catheter body; the functional assembly comprises a base and at least one energy transmission piece, the base is arranged at the far end of the catheter, the at least one energy transmission piece is arranged on one side of the base, and the base is provided with a second guide wire channel communicated with the first guide wire channel; a guide wire can movably penetrate through the first guide wire channel and the second guide wire channel, and the moving direction of the guide wire is at least one of the length directions of the first guide wire channel and the second guide wire channel; the functional assembly and the guide wire are configured to rotate relative to the catheter under the control of external force, the rotating center lines of the functional assembly and the guide wire are at least arranged in the length direction of the base, and the problem that ultrasonic energy penetrates through the guide wire in a rapid guide wire exchange scheme is solved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of tissue ablation, in particular to an ablation catheter, an ablation system and a method for manufacturing an ablation catheter. BACKGROUND

[0002] Ultrasound therapy is a physical treatment method using ultrasound as an energy form, which realizes the purpose of disease treatment through the thermal effect, mechanical effect or cavitation effect of ultrasound energy, including ultrasound tissue ablation. With the rapid development of interventional therapy technology, interventional catheter ultrasound therapy technology is also paid more and more attention.

[0003] In the related art, the ablation catheter applied to ultrasound tissue ablation adopts a sheet-shaped transducer, which is driven to rotate by a driving device to realize whole-circle ablation. However, in this kind of ablation catheter, a rapid exchange guide wire is often used, and part of the guide wire is located outside the functional component area of the ablation catheter. When the sheet-shaped transducer rotates one circle, there is a shadow of the guide wire projection in the ultrasound emission area, and the ultrasound energy is reflected or refracted by the guide wire, which may cause a treatment safety hazard. SUMMARY

[0004] In an embodiment, the present application provides an ablation catheter, an ablation system and a method for manufacturing an ablation catheter, which is beneficial to solve the problem of ultrasound energy passing through the guide wire in the rapid exchange guide wire scheme, and effectively improve the treatment safety.

[0005] In an embodiment, the present application provides an ablation catheter, comprising:

[0006] A catheter is provided with a first guide wire channel penetrating through the catheter, and the length direction of the first guide wire channel is arranged along the length direction of the catheter;

[0007] A functional component includes a base and at least one energy transmission member, the base is arranged at the distal end of the catheter, at least one energy transmission member is arranged on one side of the base, and the base is provided with a second guide wire channel in communication with the first guide wire channel;

[0008] The first guide wire channel and the second guide wire channel are used for movably penetrating the guide wire therein, and the moving direction of the guide wire is at least one of the length directions of the first guide wire channel and the second guide wire channel;

[0009] The functional component and the guide wire are configured to be controlled by an external force to rotate relative to the catheter, and the rotation center line of the functional component and the guide wire is arranged at least along the length direction of the base.

[0010] In some embodiments, at least part of the structure of the energy transmission member is close to the center position of the base along the rotation center line direction of the functional component.

[0011] In some embodiments, at least part of the second guide wire channel is arc-shaped, and at least part of the second guide wire channel has at least one first center O, and at least one of the first center O is located on the same side of the length direction of the base as the energy delivery member.

[0012] In some embodiments, at least part of the second guide wire channel is arc-shaped, and at least part of the second guide wire channel has at least one second center O”, and at least one of the second center O” is located on the different side of the length direction of the base relative to the energy delivery member.

[0013] In some embodiments, a first lumen for filling medium is arranged in the base, and the medium can at least be used for cooling the energy delivery member.

[0014] In some embodiments, the first lumen is located on one side of the length direction of the second guide wire channel.

[0015] In some embodiments, at least one of the second center O” of the second guide wire channel and the first lumen are located on the same side of the length direction of the base.

[0016] In some embodiments, the second guide wire channel is in a curved shape and penetrates at least part of the side wall of the base, which is referred to as the first side wall.

[0017] In some embodiments, the number of energy delivery members is one, and the first side wall is located on the side of the base away from the energy delivery member.

[0018] In some embodiments, a hose is further included, the hose is arranged in the catheter, one end of the hose is arranged in the base, the hose has a second lumen, along the length direction of the first guide wire channel, the second lumen at least partially overlaps with the first guide wire channel, the guide wire penetrating the first guide wire channel can be movably arranged in the second lumen, and the hose can be controlled to rotate to drive the functional assembly to rotate.

[0019] In some embodiments, the hose includes a soft layer tube, the second lumen is formed between the inner circle of the soft layer tube, and the soft layer tube is a braided layer.

[0020] Alternatively, the hose includes a soft layer tube and an isolation layer tube, the isolation layer tube is fixed to at least one of the inner and outer periphery of the soft layer tube, the second lumen is formed between the inner circle of the one located at the innermost side of the soft layer tube and the isolation layer tube, and the soft layer tube is a spiral spring.

[0021] In some embodiments, the ablation catheter further comprises an isolator, at least a portion of the isolator is disposed in the catheter, the isolator is spaced apart from the base to form at least one isolator cavity, at least a portion of the energy delivery member is located in the at least one isolator cavity, and energy disposed on the energy delivery member is capable of at least partially penetrating the isolator; the isolator cavity is configured to be filled with a medium, the medium is configured to at least partially cool the energy delivery member.

[0022] In some embodiments, a distal end of the isolator is disposed in the base, and a proximal end of the isolator is disposed in the catheter; the energy delivery member and at least a portion of the base are located in the at least one isolator cavity.

[0023] In some embodiments, the isolator further comprises a head member, the head member is located at a distal end of the functional assembly, a distal end of the base is rotatably connected to the head member, a distal end of the isolator is disposed in the head member, and a proximal end of the isolator is disposed in the catheter.

[0024] Under the control of an external force, the functional assembly and the guide wire are rotatable relative to the catheter, the isolator, and the head member.

[0025] In some embodiments, the head member is provided with a sealing hole, a central axis of the sealing hole coincides with a central axis of at least a portion of the first guide wire channel, the sealing hole is configured to movably pass the guide wire therethrough, and the sealing hole is configured to interference fit with the guide wire.

[0026] In some embodiments, the isolator is a capsule or an acoustic lens.

[0027] In some embodiments, at least a distal end of the head member is round or conical.

[0028] In some embodiments, a guide tube member is further included, the guide tube member is disposed at least in the hose and the base.

[0029] The guide tube member is provided with a guide cavity, along a length direction of the first guide wire channel, the guide cavity at least partially coincides with the first guide wire channel.

[0030] Along a length direction of the second guide wire channel, the guide cavity at least partially coincides with the second guide wire channel, and the guide tube member is configured to movably pass the guide wire therethrough.

[0031] In some embodiments, the energy delivery member is a curved transducer or a planar transducer; and / or,

[0032] The ablation catheter further comprises an imaging transducer, the imaging transducer is disposed on the base.

[0033] It should be noted that any of the above embodiments or combinations are a technical solution, which is the protection scope of the present application.

[0034] In an embodiment, the present application provides an ablation system, comprising:

[0035] an energy generator configured to generate ablation energy;

[0036] an ablation catheter comprising:

[0037] a catheter provided with a first guide wire channel extending through the catheter, at least a portion of the first guide wire channel extending along a length direction of the catheter;

[0038] a functional assembly comprising a base and at least one energy delivery member, at least the energy delivery member coupled to the energy generator and configured to receive the ablation energy;

[0039] the base disposed at a distal end of the catheter, the base provided with a second guide wire channel in communication with the first guide wire channel, at least one of the energy delivery members disposed on a side of the base;

[0040] the first guide wire channel and the second guide wire channel for a guide wire to move through, a movement direction of the guide wire being at least one of a length direction of the first guide wire channel and the second guide wire channel;

[0041] the functional assembly and the guide wire configured to be controlled to rotate, under the control of an external force, the functional assembly and the guide wire being able to rotate relative to the catheter.

[0042] In an embodiment, the present application provides a method for manufacturing an ablation catheter, comprising at least the following steps:

[0043] providing a catheter, opening a first guide wire channel in the catheter, the first guide wire channel extending along a length direction of the catheter;

[0044] providing a base disposed at a distal end of the catheter, fixing at least one energy delivery member on at least one side of the base, and opening at least one second guide wire channel in communication with the first guide wire channel on the base;

[0045] the first guide wire channel and the second guide wire channel for a guide wire to move through, a movement direction of the guide wire being at least one of a length direction of the first guide wire channel and the second guide wire channel; the functional assembly and the guide wire configured to be controlled to rotate, under the control of an external force, the functional assembly and the guide wire being able to rotate relative to the catheter.

[0046] In some embodiments, the present application provides an ablation catheter, an ablation system and a method for manufacturing the ablation catheter, in the process of application of the ablation catheter, a guide wire is sequentially arranged in a first guide wire channel of the catheter and a second guide wire channel of a base, a functional assembly is moved to a target site under the guidance of the guide wire, and then the functional assembly and the guide wire are rotated relative to the catheter under the control of an external force, so that the ablation catheter performs whole-circle ablation. In the process of rotation of the base, the guide wire in the ultrasonic emission area of the functional assembly is always located in the base, and the guide wire does not pass through the ultrasonic emission area of the functional assembly, which is beneficial to reduce or even avoid the interference of the guide wire on the reflection or refraction of the ultrasonic emission area, and is beneficial to improve the success rate and safety of the operation. BRIEF DESCRIPTION OF DRAWINGS

[0047] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed in the description of the embodiments of the present application will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained according to the contents of the embodiments of the present application and these drawings without creative labor.

[0048] Figure 1 is a cross-sectional view of the ablation catheter provided by the specific embodiment of the present application;

[0049] Figure 2 is one of the cross-sectional views of the guide wire arranged in the ablation catheter provided by the specific embodiment of the present application (at least hiding the hose);

[0050] Figure 3 is a structural schematic view of the functional assembly provided by the specific embodiment of the present application;

[0051] Figure 4 is the second cross-sectional view of the guide wire arranged in the ablation catheter provided by the specific embodiment of the present application;

[0052] Figure 5 is a distribution schematic view of the first lumen and the second guide wire channel in the functional assembly provided by the specific embodiment of the present application;

[0053] Figure 6 is Figure 4 is an enlarged view at A;

[0054] Figure 7 is a cross-sectional view of the ablation catheter without a separation piece provided by the specific embodiment of the present application;

[0055] Figure 8 is a partial structural schematic view of the ablation catheter provided by the specific embodiment of the present application.

[0056] The figures are marked as follows:

[0057] 1. Catheter; 11. First guidewire channel; 2. Functional assembly; 21. Base; 211. Second guidewire channel; 212. First lumen; 22. Energy delivery member; 3. Guidewire; 4. Hose; 41. Soft layer tube; 42. Insulation layer tube; 43. Second lumen; 44. Third lumen; 5. Insulation member; 51. Insulation cavity; 52. Head member; 521. Sealing hole; 6. Guide tube member. DETAILED DESCRIPTION

[0058] It is to be understood that the examples and / or embodiments described herein are merely illustrative of the principles of the present application. Numerous modifications may be made by one skilled in the art without departing from the scope of the present application. For example, elements described herein can be combined, deleted, modified, or supplemented to form other embodiments. Accordingly, the examples and / or embodiments described herein are not intended to limit the scope of the present application.

[0059] Unless otherwise defined, all technical and / or scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the application pertains. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of embodiments of the application, exemplary methods and / or materials are described below. In case of conflict, the patent specification, including definitions, will control. In addition, the materials, methods, and examples are illustrative only and are not intended to be necessarily limiting.

[0060] In the description of the present application, unless otherwise clearly specified and limited, the terms "connected", "connected", "fixed" should be understood broadly, for example, can be fixedly connected, can be detachably connected, or integrated; can be mechanically connected, can be electrically connected; can be directly connected, can be indirectly connected through an intermediate medium, can be internal communication of two elements or interaction relationship between two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances. In addition, the description of the terms "first", "second" and the like is only used to distinguish in the description, and has no special meaning.

[0061] In the present application, the distal end refers to the end of the ablation device and at least part of the constituent members of the ablation device which is away from the operator during use (or in other words, the distal end refers to the end of the ablation device and at least part of the constituent members of the ablation device which first contacts / intervenes the biological tissue during use on the biological body), and the proximal end refers to the end of the ablation device and at least part of the constituent members of the ablation device which is close to the operator during use (or in other words, the proximal end refers to the end of the ablation device and at least part of the constituent members of the ablation device which is further away from the biological tissue than the distal end during use on the biological body).

[0062] As shown in Figures 1-3 At least one embodiment of the present application provides an ablation catheter, which comprises a catheter 1 and a functional assembly 2. The catheter 1 is provided with a first guide wire channel 11 extending through the catheter 1, and the length direction of the first guide wire channel 11 extends along the length direction of the catheter 1. The functional assembly 2 comprises a base 21 and at least one energy transmission member 22. The base 21 is arranged at the distal end of the catheter 1. The at least one energy transmission member 22 is arranged on one side of the base 21. The base 21 is provided with a second guide wire channel 211 which is in communication with the first guide wire channel 11. The first guide wire channel 11 and the second guide wire channel 211 are used for movably passing a guide wire 3 therethrough, and the moving direction of the guide wire 3 is at least one of the length directions of the first guide wire channel 11 and the second guide wire channel 211. The functional assembly 2 and the guide wire 3 are configured to be able to rotate relative to the catheter 1 under the control of an external force, and the rotation center line of the functional assembly 2 and the guide wire 3 is arranged at least along the length direction of the base 21. For example, during the application of the ablation catheter, the guide wire 3 is sequentially passed through the first guide wire channel 11 of the catheter 1 and the second guide wire channel 211 of the base 21, and the ablation catheter is moved to the target site under the guidance of the guide wire 3. Then, under the control of the external force, the functional assembly 2 and the guide wire 3 rotate relative to the catheter 1, so that the functional assembly 2 on the ablation catheter performs a full-circle ablation. During the rotation of the base 21, the guide wire 3 in the ultrasonic emission area of the functional assembly 2 is always located in the base 21, and the guide wire 3 does not pass through the ultrasonic emission area of the functional assembly 2, which is beneficial to reduce or even avoid the interference of the reflection or refraction of the guide wire 3 on the ultrasonic emission area, and is beneficial to improve the success rate and safety of the operation.

[0063] In some embodiments, as shown in Figure 3 Along the direction of the rotation center line of the functional assembly 2, at least part of the structure of the energy transmission member 22 is close to the center position of the base 21. During the rotation of the base 21, the closer the energy transmission member 22 is to the center position of the base 21, the larger the sound field emission area of the energy transmission member 22.

[0064] Optionally, as shown in Figure 4As shown, at least part of the second guide wire channel 211 is arc-shaped, and at least part of the second guide wire channel 211 has at least one first center O, which is located on the same side of the energy transmission member 22 in the length direction of the base 21. In other words, the second guide wire channel 211 is eccentrically curved away from the energy transmission member 22, thereby reducing the occupation of the central position of the energy transmission member 22, and further enabling at least part of the structure of the energy transmission member 22 to be arranged close to the central position of the base 21.

[0065] In some embodiments, as shown, Figure 5 As shown, at least part of the second guide wire channel 211 is arc-shaped, and at least part of the second guide wire channel 211 has at least one second center O”, which is located on the different side of the energy transmission member 22 in the length direction of the base 21.

[0066] In some embodiments, the first lumen 212 for filling the medium is arranged in the base 21, and the medium can at least be used to cool the energy transmission member 22, thereby reducing the temperature of the functional assembly 2 and improving the working reliability of the ablation catheter. Optionally, the first lumen 212 is located on one side of the second guide wire channel 211 in the length direction.

[0067] In some embodiments, at least one second center O” of the second guide wire channel 211 is located on the same side of the first lumen 212 in the length direction of the base 21. In other words, the second guide wire channel 211 is eccentrically curved away from the first lumen 212, thereby increasing the wall thickness between the first lumen 212 and the second guide wire channel 211, and facilitating the increase of the structural strength. Furthermore, the second guide wire channel 211 is curved to avoid, so that at least part of the first lumen 212 can be arranged closer to the energy transmission member 22, thereby reducing the distance between the first lumen 212 and the energy transmission member 22 and improving the cooling effect of the energy transmission member 22.

[0068] Optionally, the second guide wire channel 211 is in a curved form and penetrates at least part of the side wall of the base 21, which is referred to as the first side wall. The second guide wire channel 211 can penetrate the wall of the base 21, so that the second guide wire channel 211 has a notch between the two ends in the length direction of the second guide wire channel 211. While ensuring miniaturization, the wall thickness between the first lumen 212 and the second guide wire channel 211 is maximized, so that the structure of the first lumen 212 is more firm. At the same time, the central position occupied by the energy transmission member 22 is maximally avoided, which helps to increase the structural rigidity of the base 21, enables at least part of the structure of the energy transmission member 22 to be closer to the central position of the base 21, and is beneficial to increase the sound field emission area.

[0069] In some embodiments, the number of energy transmission members 22 is one, and the first side wall is located on the side of the base 21 away from the energy transmission member 22.

[0070] In some embodiments, as shown in Figure 6 The ablation catheter further comprises a hose 4 disposed in the catheter 1, a distal end of the hose 4 in a length direction is disposed in the base 21, and the hose 4 has a second lumen 43. The second lumen 43 is at least partially coincident with the first guide wire channel 11 in a length direction of the first guide wire channel 11, and the guide wire 3 disposed in the first guide wire channel 11 can be movably disposed in the second lumen 43. The hose 4 can be controlled to rotate to drive the functional assembly 2 to rotate. A proximal end of the hose 4 is directly or indirectly connected to a driving structure (such as a motor), and the motor drives the hose 4 to rotate, and the hose 4 drives the functional assembly 2 to rotate.

[0071] In some embodiments, the hose 4 comprises a soft layer tube 41, and the second lumen 43 is formed between inner circles of the soft layer tube 41, and the soft layer tube 41 is a braided layer. Alternatively, in other embodiments, the hose 4 comprises the soft layer tube 41 and an isolation layer tube 42, the isolation layer tube 42 is fixed to at least one of an inner circle and an outer circle of the soft layer tube 41, the second lumen 43 is formed between inner circles of the one of the soft layer tube 41 and the isolation layer tube 42 which is located at the innermost side, the isolation layer tube 42 can play a role of isolating the medium in the second lumen 43, and the soft layer tube 41 is a spiral spring.

[0072] In some embodiments, as shown in Figure 2 and Figure 5 The ablation catheter further comprises an isolation member 5, at least a part of the isolation member 5 is disposed in the catheter 1, and the isolation member 5 is provided with a gap with the base 21 to form at least one isolation chamber 51. At least a part of the energy delivery member 22 is located in the at least one isolation chamber 51, and the energy provided on the energy delivery member 22 can at least partially penetrate the isolation member 5. The isolation chamber 51 is used to fill a medium, and the medium can at least be used to cool the energy delivery member 22. Alternatively, the isolation member 5 is a capsule or an acoustic lens, and the energy of the energy delivery member 22 can penetrate the isolation member 5 to achieve the propagation of ultrasonic energy. Alternatively, the isolation member 5 can also play a role of isolating blood.

[0073] In some embodiments, a distal end of the isolation member 5 is disposed in the base 21, and a proximal end of the isolation member 5 is disposed in the catheter 1. The energy delivery member 22 and at least a part of the base 21 are located in the at least one isolation chamber 51. A gap is provided between the catheter 1 and the soft layer tube 41 to form at least one third lumen 44, and the third lumen 44, the isolation chamber 51, the first lumen 212 and the second lumen 43 are sequentially communicated. Exemplarily, the medium sequentially passes through the third lumen 44, the isolation chamber 51, the first lumen 212 and the second lumen 43 to achieve a circulating flow, and at least the cooling effect on the functional assembly 2 is improved.

[0074] In some embodiments, the isolation member 5 further comprises a head member 52, which is located at the distal end of the functional assembly 2. The distal end of the base 21 is rotatably connected to the head member 52. The distal end of the isolation member 5 is provided at the head member 52, and the proximal end of the isolation member 5 is provided at the catheter 1. Under the control of external force, the functional assembly 2 and the guide wire 3 can rotate relative to the catheter 1, the isolation member 5 and the head member 52. During the movement of the ablation catheter, the head member 52 can at least play a role of guiding and advancing.

[0075] In some embodiments, the head member 52 is provided with a sealing hole 521, the central axis of which coincides with the central axis of at least part of the first guide wire channel 11. The sealing hole 521 can be used to movably pass the guide wire 3, and is used to be in interference fit with the guide wire 3. The head member 52 is made of a soft material, which can be an elastic material, such as a thermoplastic elastomer, and the elastic material at least includes low-hardness materials such as polyester, polyurethane, styrene or polyolefin. The sealing hole 521 of the head member 52 closely fits the outer wall of the guide wire 3. The interference fit of the sealing hole 521 with the guide wire 3 is conducive to sealing the isolation cavity 51, and reduces or even prevents the leakage of the medium during the circulation of the medium.

[0076] In some embodiments, at least the distal end of the head member 52 is round or conical, which reduces or even prevents the head member 52 from damaging the blood vessel during the movement of the ablation catheter.

[0077] In some embodiments, as shown in Figure 7 , the ablation catheter can not be provided with the isolation member 5, and the head member 52 is provided at the distal end of the base 21. Alternatively, under the control of external force, the guide wire 3, the functional assembly 2 and the head member 52 can rotate relative to the catheter 1.

[0078] In some embodiments, as shown in Figure 6 and Figure 8 , the ablation catheter further comprises a guide tube member 6, which is provided at least in the hose 4 and the base 21. The guide tube member 6 is provided with a guide cavity, which at least partially coincides with the first guide wire channel 11 along the length direction of the first guide wire channel 11. The guide cavity at least partially coincides with the second guide wire channel 211 along the length direction of the second guide wire channel 211. The guide tube member 6 is used for movably passing the guide wire 3 in the guide cavity, which is conducive to improving the convenience of passing the guide wire 3. The diameter of the guide cavity is designed to pass the guide wire 3 with a size of 0.2mm-0.5mm. Alternatively, the guide tube member 6 extends at least from the distal end of the base 21 to the proximal end of the catheter 1.

[0079] In some possible related technologies, a ring transducer is used for ablation, but the ring transducer is a 360° uniform sound field, and the sound intensity is higher near the surface of the ring transducer and lower far from the surface of the ring transducer. Therefore, the inventors believe that the tissues near the surface of the ring transducer are first damaged, and the acoustic characteristics of these damaged tissues may form a new acoustic barrier, making it difficult for the deep tissues (far from the ring transducer) to continue to be damaged.

[0080] In some other embodiments, the energy delivery member 22 is a curved transducer or a planar transducer. The curved transducer or the planar transducer can form a non-uniform sound field distribution, so that the sound intensity is higher at a position far from the surface of the energy delivery member 22, and the sound intensity is lower at a position close to the surface of the energy delivery member 22. For example, during the implementation of the ultrasonic treatment, the tissues far from the surface of the energy delivery member 22 (which often represent deep tissues) are first damaged, and these first damaged tissues become an acoustic barrier (including reflection or scattering effects of ultrasound), so that the subsequent ultrasonic energy is gradually applied to the tissues from deep to shallow; in this way, both the deep tissues and the shallow tissues can achieve better tissue damage.

[0081] In some other embodiments, the ablation catheter further includes an imaging transducer (such as an imaging ultrasonic transducer), which is arranged on the base 21. The imaging transducer enables the same ablation catheter to achieve both treatment and imaging functions, forming an ultrasonic diagnosis and treatment integrated solution.

[0082] At least one embodiment of the present application provides an ablation system, which includes an energy generator and an ablation catheter. The energy generator is configured to generate ablation energy. The ablation catheter includes a catheter 1 and a functional assembly 2. The catheter 1 is provided with a first guide wire channel 11 extending through the catheter 1, and at least part of the first guide wire channel 11 extends along the length direction of the catheter 1. The functional assembly 2 includes a base 21 and at least one energy delivery member 22. The at least one energy delivery member 22 is coupled to the energy generator and is configured to receive the ablation energy. The base 21 is arranged at the distal end of the catheter 1, and the base 21 is provided with a second guide wire channel 211 in communication with the first guide wire channel 11. The at least one energy delivery member 22 is arranged on one side of the base 21. The first guide wire channel 11 and the second guide wire channel 211 are used for movably passing a guide wire 3 therethrough, and the movement direction of the guide wire 3 is at least one of the length directions of the first guide wire channel 11 and the second guide wire channel 211. The functional assembly 2 and the guide wire 3 can be controlled to rotate, and under the control of an external force, the functional assembly 2 and the guide wire 3 can rotate relative to the catheter 1.

[0083] At least one embodiment of the present application provides a method for manufacturing an ablation catheter, which at least includes the following steps:

[0084] A catheter 1 is provided, and a first guide wire channel 11 is formed in the catheter 1, with the length direction of the first guide wire channel 11 extending along the length direction of the catheter 1.

[0085] A base 21 is provided, which is arranged at the distal end of the catheter 1, and at least one energy transmission member 22 is fixed on at least one side of the base 21, and at least one second guide wire channel 211 is formed in the base 21 and communicates with the first guide wire channel 11.

[0086] The first guide wire channel 11 and the second guide wire channel 211 are used for movably passing the guide wire 3 therethrough, and the moving direction of the guide wire 3 is at least one of the length directions of the first guide wire channel 11 and the second guide wire channel 211. The functional assembly 2 and the guide wire 3 are configured to be capable of being controlled to rotate, and under the control of external force, the functional assembly 2 and the guide wire 3 are capable of rotating relative to the catheter 1.

[0087] It should be noted that the technical solutions formed by any one of the above-mentioned embodiments (or examples) or the combination of any embodiments (or examples) are all within the protection scope of the present application.

[0088] Whenever numerical ranges are indicated in this application, what is meant are end points that include any and all intervening values (fractional and integral) within the indicated range. The phrases "range between the first indicated number and the second indicated number" and "range from the first indicated number to the second indicated number" are interchangeable and mean including the first and second indicated numbers and all the intervening values between them.

[0089] As used herein, the terms "about" and / or "approximately" when used in conjunction with a numerical value and / or a range, generally mean those numbers and / or ranges close to the stated value and / or range. In some instances, the terms "about" and "approximately" can mean within ±10% of the stated value. For example, in some instances, "about 100 [units]" can mean within ±10% of 100 (e.g., 90 to 110). The terms "about" and "approximately" can be used interchangeably.

[0090] As used herein, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. For example, the terms "a compound" or "at least one compound" can include a plurality of compounds, including mixtures thereof.

[0091] The term "consisting essentially of means that the composition, method or structure can include additional ingredients, steps and / or components, but only if the additional ingredients, steps and / or components do not materially alter the basic and novel characteristics of the claimed composition, method or structure.

[0092] Implementation of the method and / or system of embodiments of the application can involve performing or completing selected tasks manually, automatically, or a combination thereof. Moreover, according to actual instrumentation and equipment of embodiments of the method and / or system of the application, several selected tasks could be implemented by hardware, by software or by firmware or by a combination thereof using an operating system.

[0093] For example, hardware for performing selected tasks according to embodiments of the application could be implemented. As software, selected tasks according to embodiments of the application could be implemented as a plurality of software instructions being executed by a computer using any suitable operating system. In an exemplary embodiment of the application, one or more tasks according to exemplary embodiments of method and / or system as described herein are performed by a data processor, such as a computing platform for executing a plurality of instructions. Optionally, the data processor includes a volatile memory for storing instructions and / or data and / or a non-volatile storage, for example, a magnetic hard-disk and / or removable media to store instructions and / or data. Optionally, a user interface is provided for allowing a user to interact with the data processor. Optionally, a display is provided for displaying a user interface of a user interface input / output device, such as a keyboard or a mouse.

[0094] It is understood that certain features of the application, which are, individually, described as though acting only in conjunction with other features, can be provided independently of other features. That is, it is understood that the features of the application can be used in any combination or sub-combination thereof. It is understood that certain features of the application, which are, individually, described as though acting only in conjunction with other features, can be provided independently of other features. That is, it is understood that the features of the application can be used in any combination or sub-combination thereof. It is understood that certain features of the application, which are, individually, described as though acting only in conjunction with other features, can be provided independently of other features. That is, it is understood that the features of the application can be used in any combination or sub-combination thereof. It is understood that certain features of the application, which are, individually, described as though acting only in conjunction with other features, can be provided independently of other features. That is, it is understood that the features of the application can be used in any combination or sub-combination thereof. It is understood that certain features of the application, which are, individually, described as though acting only in conjunction with other features, can be provided independently of other features. That is, it is understood that the features of the application can be used in any combination or sub-combination thereof.

[0095] While the application has been described in connection with specific embodiments thereof, it will be understood that it is capable of further modifications and this application is intended to cover any variations, uses, or adaptations of the application following, in general, the principles of the application and including such departures from the present disclosure as come within known or customary practice within the art to which the application pertains.

Claims

1. An ablation catheter, characterized in that: include: The catheter is provided with a first guidewire channel running through the catheter, wherein the length direction of the first guidewire channel extends along the length direction of the catheter; A functional component comprising a base and at least one energy transmission component, wherein the base is disposed at the distal end of the catheter, the at least one energy transmission component is disposed on one side of the base, and the base is provided with a second guidewire channel communicating with the first guidewire channel; The first guidewire channel and the second guidewire channel are used for allowing a guidewire to movably pass therethrough, and the moving direction of the guidewire is at least one of the length directions of the first guidewire channel and the second guidewire channel; The functional component and the guide wire are configured to be rotatable relative to the catheter under the control of an external force, and the rotation center lines of the functional component and the guide wire are at least arranged along the length direction of the base.

2. The ablation catheter according to claim 1, characterized in that Along the rotation centerline direction of the functional component, at least a portion of the structure of the energy transmission member is close to the center position of the base.

3. The ablation catheter according to claim 2, characterized in that At least part of the second guide wire channel is arc-shaped, and at least part of the second guide wire channel has at least one first center O. The at least one first center O and the energy transmission component are located on the same side of the length direction of the base.

4. The ablation catheter according to claim 1, characterized in that At least part of the second guide wire channel is arc-shaped, and at least part of the second guide wire channel has at least one second center O", and at least one second center O" is located on a different side of the base in the length direction relative to the energy transmission component.

5. The ablation catheter according to claim 4, characterized in that A first tube cavity for filling a medium is provided in the base, and the medium can at least be used to cool the energy transfer component.

6. The ablation catheter according to claim 5, characterized in that The first lumen is located on one side of the second guidewire channel in the length direction.

7. The ablation catheter according to claim 5, characterized in that At least one second circle center O" of the second guidewire channel and the first lumen are located on the same side of the length direction of the base.

8. The ablation catheter according to any one of claims 1 to 7, characterized in that: The second guide wire channel is curved and passes through at least a portion of the side wall of the base, which is recorded as the first side wall.

9. The ablation catheter according to claim 8, characterized in that The number of the energy transmission component is one, and the first side wall is located on a side of the base facing away from the energy transmission component.

10. The ablation catheter according to any one of claims 1 to 7, characterized in that: It also includes a hose, which is arranged in the catheter, one end of the hose is arranged on the base, and the hose has a second lumen; along the length direction of the first guidewire channel, the second lumen and the first guidewire channel at least partially overlap, the guidewire passing through the first guidewire channel can be movably passed through the second lumen, and the hose can be controlled to rotate to drive the functional component to rotate.

11. The ablation catheter according to claim 10, characterized in that: The hose comprises a soft layer tube, the second tube cavity is formed between the inner circles of the soft layer tube, and the soft layer tube is a braided layer; Alternatively, the hose includes a soft layer tube and an isolation layer tube, the isolation layer tube is fixed to at least one of the inner circumference and the outer circumference of the soft layer tube, the second tube cavity is formed between the inner circle of the soft layer tube and the isolation layer tube located on the innermost side, and the soft layer tube is a coil spring.

12. The ablation catheter according to any one of claims 1 to 7, characterized in that: The ablation catheter further includes an isolation member, at least a portion of which is disposed on the catheter, a gap being formed between the isolation member and the base to form at least one isolation cavity, at least a portion of the energy transmission member being located within the at least one isolation cavity, and energy applied to the energy transmission member being able to at least partially penetrate the isolation member; The isolation cavity is used to be filled with a medium, and the medium can at least be used to cool the energy transmission component.

13. The ablation catheter according to claim 12, characterized in that: The distal end of the isolation element is arranged on the base, and the proximal end of the isolation element is arranged on the catheter; the energy transmission element and at least a part of the base are located in at least one isolation cavity.

14. The ablation catheter according to claim 12, characterized in that The isolator further comprises a head component, the head component is located at the distal end of the functional component, the distal end of the base is rotatably connected to the head component, the distal end of the isolator is disposed on the head component, and the proximal end of the isolator is disposed on the catheter; Under the control of external force, the functional component and the guide wire can rotate relative to the catheter, the spacer and the head component.

15. The ablation catheter according to claim 14, characterized in that The head component is provided with a sealing hole, the central axis of the sealing hole coincides with the central axis of at least part of the first guidewire channel, the sealing hole can be used to movably pass the guidewire, and the sealing hole is used for interference fit with the guidewire.

16. The ablation catheter according to claim 12, characterized in that The isolation member is a capsule or an acoustic lens.

17. The ablation catheter according to claim 14, characterized in that At least the distal end of the head component is rounded or tapered.

18. The ablation catheter according to claim 11, characterized in that It also includes a guide pipe, which is at least arranged in the hose and the base; The guide tube is provided with a guide cavity, and along the length direction of the first guide wire channel, the guide cavity and the first guide wire channel at least partially overlap; Along the length direction of the second guide wire channel, the guide cavity and the second guide wire channel at least partially overlap, and the guide tube is used for allowing the guide wire to movably pass through the guide cavity.

19. The ablation catheter according to claim 1, characterized in that The ablation catheter further includes an imaging transducer, which is disposed on the base.

20. An ablation system, characterized in that: include: an energy generator configured to generate ablative energy; An ablation catheter, comprising: The catheter is provided with a first guidewire channel running through the catheter, wherein the length direction of the first guidewire channel extends along the length direction of the catheter; a functional assembly comprising a base and at least one energy-transmitting element, at least the energy-transmitting element being coupled to the energy generator and configured to receive the ablation energy; The base is provided at the distal end of the catheter, the base is provided with a second guidewire channel communicating with the first guidewire channel, and at least one energy transmission component is provided on one side of the base; The first guidewire channel and the second guidewire channel are used for allowing a guidewire to movably pass therethrough, and the moving direction of the guidewire is at least one of the length directions of the first guidewire channel and the second guidewire channel; The functional component and the guide wire are configured to be controllably rotatable. Under external force control, the functional component and the guide wire can rotate relative to the catheter.

21. A method for manufacturing an ablation catheter, characterized in that: At least the following steps are included: Providing a catheter, and defining a first guidewire channel in the catheter so that the length direction of the first guidewire channel extends along the length direction of the catheter; Providing a base, the base being disposed at the distal end of the catheter, at least one energy transmission member being fixed on at least one side of the base, and at least one second guidewire channel being in communication with the first guidewire channel being defined on the base; The first guidewire channel and the second guidewire channel are used for allowing a guidewire to movably pass therethrough, and the moving direction of the guidewire is at least one of the length directions of the first guidewire channel and the second guidewire channel; the functional component and the guidewire are configured to be controllable to rotate, and under the control of external force, the functional component and the guidewire can rotate relative to the catheter.

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