An automated drug dispensing system and method based on liquid jet swirl-enhanced stirring

An automated drug dispensing system that enhances agitation through liquid jet swirl can monitor and dynamically adjust injection parameters in real time, solving the problems of uneven drug dispensing and low efficiency, and achieving efficient and stable drug preparation.

CN120771774BActive Publication Date: 2025-11-14RIGHTLEDER (SHANGHAI) TECH CO LTD
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Patent Information

Application Number
CN202511278036.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-09-09
Publication Date
2025-11-14
Estimated Expiration
2045-09-09

AI Technical Summary

Technical Problem

In existing technologies, the drug dissolution process is not monitored in real time and is not dynamically adjusted, resulting in uneven drug dissolution, low efficiency, unstable drug quality, and large batch-to-batch differences.

Method used

An automated drug dispensing system based on liquid jet swirl-enhanced stirring is adopted. The monitoring unit monitors the drug concentration in real time, the data processor analyzes the concentration fluctuation, and the jet controller adjusts the jet parameters, including the jet angle and pressure, to form a closed-loop process to optimize mixing.

Benefits of technology

It improves the uniformity and efficiency of drug dissolution, reduces reliance on manual labor, ensures stable drug preparation quality, and reduces batch variations caused by fixed equipment parameters.

✦ Generated by Eureka AI based on patent content.

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Abstract

This invention relates to the field of water treatment and fluid mixing technology, and particularly to an automatic dispensing system and method based on liquid jet swirl enhanced stirring. The system monitors the drug concentration at each monitoring point to determine the concentration fluctuation equivalent based on the drug concentration at each monitoring point at the same time. Based on the concentration fluctuation equivalent at each time point during the dispensing process, it determines a concentration fluctuation time-domain graph to identify fluctuation subgraphs and stable subgraphs. Based on the duration of the fluctuation subgraph, it determines whether to formulate a jet adjustment strategy, identifies all fluctuation moments in the fluctuation subgraph, and determines the concentration fluctuation monitoring points at each fluctuation moment. Based on the concentration fluctuation monitoring points, it determines the dispensing adjustment strategy. This invention enhances mixing by real-time monitoring and analysis of concentration fluctuations, and specifically adjusts jet parameters to reduce deviations and avoid ineffective stirring.
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Description

Technical Field

[0001] This invention relates to the field of water treatment and fluid mixing technology, and in particular to an automated dispensing and mixing system and method based on liquid jet swirl enhanced stirring. Background Technology

[0002] Currently, conventional dosing systems in the water treatment industry generally adopt the following forms. After manually adding solid chemicals or liquid chemicals requiring dilution into the dosing tank: one method is to directly add water to dissolve them in the dosing tank. However, if the water treatment system cannot be shut down during the dissolution process, it will cause large fluctuations in the dosing concentration within a short period of time, thus affecting the safe operation of the system; a more common configuration method is to separate the dissolution and dosing processes, using two dosing tanks. In this dual-tank configuration method, there are usually two implementation methods: First, using two dosing tanks of the same size as backups for each other. Both dosing tanks are equipped with a mixer and a dosing pump suction port. This method requires two mixers, and the dosing tanks must be of the same specifications; Second, raising the dissolution tank and installing a mixer on the dissolution tank, with the chemical solution flowing into the dosing tank by gravity after dissolution. This method requires building a dosing platform to raise the dissolution tank. In addition, conventional drug dissolution operations are generally manual. During the stirring process, the operator needs to wait in the drug addition room. After the drug dissolution is completed, the operator either needs to manually switch the drug tank or open the valve to put the dissolved drug solution from the dissolution tank into the drug addition tank. The operation cycle is relatively long.

[0003] Chinese Patent Publication No. CN217725293U discloses an automatic pharmaceutical dissolving machine, relating to the field of wastewater treatment technology. The machine includes a dissolving machine body comprising a dry powder dosing system, a water supply system, a mixer and solution tank system, an electrical control system, an overflow and wastewater exchange valve assembly, and a dosing system. A support is fixedly connected to the upper surface of the dissolving machine body. The dry powder dosing system is connected to the top of the dissolving machine body, the water supply system is connected to the side of the dissolving machine body, the mixer system is located inside the dissolving machine body, the electrical control system is connected to the right side of the dry powder dosing system, and the overflow and wastewater exchange valve assembly is connected to the lower side wall of the dissolving machine body. High-speed hydraulic dispersion of the pharmaceutical agent or powder reduces dissolution time, followed by low-speed mixing to improve solution uniformity, ensuring ideal reaction time and constant concentration in each solution tank, and avoiding any direct pathway between the pre-mixing tank and the solution storage tank. Therefore, the existing technology has the following problems:

[0004] The existing drug dissolution process is set based on historical experience, without real-time monitoring of the process or analysis of the monitoring data to dynamically adjust the process. This results in problems such as uneven drug dissolution, low efficiency, unstable drug quality, and large batch-to-batch differences. Summary of the Invention

[0005] To address this, the present invention provides an automated drug dissolution and preparation system and method based on liquid jet swirl enhanced stirring, which overcomes the problems of uneven drug dissolution, low efficiency, unstable drug preparation quality, and large batch differences caused by prior art which sets the system based on historical experience without real-time monitoring of the drug dissolution process and without analyzing the monitoring data to dynamically adjust the drug dissolution process.

[0006] To achieve the above objectives, on the one hand, the present invention provides an automatic dissolving and dispensing system based on liquid jet swirl enhanced stirring, including a dissolving tank for dispensing water treatment agents, a dosing tank connected to the dissolving tank and used to contain the water treatment agents, and a dissolving and dispensing pump connected to the dissolving tank and the dosing tank respectively and used to pump out the water treatment agents;

[0007] It also includes: a monitoring unit installed inside the drug dissolving tank to monitor the drug concentration at each monitoring point, and a programmable controller connected to the drug dissolving tank, the drug dosing tank and the drug dissolving and delivery pump respectively;

[0008] The program controller includes a data processor and an injection controller;

[0009] The data processor is configured to determine the concentration fluctuation equivalent based on the drug concentration at each monitoring site at the same time.

[0010] The injection controller is used to determine the concentration fluctuation time domain diagram based on the concentration fluctuation equivalent at each moment during the drug preparation process to determine the fluctuation sub-diagram and the stable sub-diagram, to determine whether to formulate an injection adjustment strategy based on the duration of the fluctuation sub-diagram, to determine all fluctuation moments of the fluctuation sub-diagram and to determine the concentration fluctuation monitoring point at each fluctuation moment, and to determine the drug dissolution adjustment strategy based on the concentration fluctuation monitoring point.

[0011] The drug dissolving adjustment strategy includes adjusting the injection angle and injection pressure of the injection head.

[0012] As a preferred technical solution for an automated dispensing and mixing system based on liquid jet swirl enhanced stirring, the dosing tank includes:

[0013] The inlet is located on the upper side wall of the dosing tank and is connected to the dissolving and dispensing pump via a dosing pipe to pump water treatment agents into the dosing tank.

[0014] A drug delivery solenoid valve is installed on the drug delivery tube;

[0015] The first level switch group is used to determine the level status of the dosing tank;

[0016] The first liquid level switch group includes a first high liquid level switch and a first low liquid level switch, and the liquid level state includes reaching the first high liquid level, being below the first low liquid level, and being between the first high liquid level and the first low liquid level.

[0017] As a preferred technical solution for an automated drug dispensing system based on liquid jet swirl-enhanced stirring, the drug dispensing tank includes:

[0018] A water inlet is located at the top of the dissolving tank and is used to replenish water to the dissolving tank.

[0019] The suction port is located on the lower part of the side wall of the dissolving tank and is connected to the dissolving and delivery pump through a circulation pipe for pumping the drug outward;

[0020] A drug-absorbing filter, which is connected to one end of the drug-dissolving tank inside the drug-absorbing port, is used to filter solid particles;

[0021] The spray nozzle is located on the upper side wall of the dissolving tank and is connected to the dissolving and delivery pump through a circulation pipe to pump the drug into the dissolving tank.

[0022] The spray head, which is connected to the inside of the dissolving tank of the spray nozzle, includes an angle adjustment mechanism and a pressure adjustment mechanism. The angle adjustment mechanism is used to adjust the angle of the spray flow relative to the horizontal plane, and the pressure adjustment mechanism is used to adjust the spray flow rate.

[0023] The second liquid level switch group is used to determine the liquid level status of the dissolving tank;

[0024] The second liquid level switch group includes a second high liquid level switch and a second low liquid level switch, and the liquid level states include reaching the second high liquid level, being below the second low liquid level, and being between the second high liquid level and the second low liquid level.

[0025] As a preferred technical solution for an automated drug dispensing system based on liquid jet swirl enhanced stirring, the data processor determines the concentration fluctuation equivalent based on the ratio of the average deviation to the average value of the drug concentration at each monitoring point at the same time, so that the jet controller determines the concentration fluctuation time domain map based on the concentration fluctuation equivalent at each time during the drug dispensing process, and divides the concentration fluctuation time domain map into a fluctuation sub-map and a stable sub-map.

[0026] As a preferred technical solution for an automated drug dispensing system based on liquid jet swirl enhanced stirring, the jet controller responds to the duration of the fluctuation subgraph being greater than a preset duration, determines and formulates a jet adjustment strategy, and defines the moment when the concentration fluctuation equivalent in the fluctuation subgraph is greater than the preset fluctuation equivalent as the fluctuation moment.

[0027] As a preferred technical solution for an automated drug dispensing system based on liquid jet swirl-enhanced stirring, the jet controller determines the concentration fluctuation monitoring point at any given fluctuation moment based on the difference between the drug concentration at each monitoring point and the corresponding average concentration, including:

[0028] Based on the judgment result that the difference between the drug concentration at the monitoring point and the average concentration is greater than the preset difference, the corresponding monitoring point is determined as the concentration fluctuation monitoring point;

[0029] Alternatively, based on the judgment result that the difference between the drug concentration and the average concentration at each monitoring point is less than a preset difference, the monitoring point with the largest difference between the drug concentration and the average concentration is determined as the concentration fluctuation monitoring point;

[0030] Each fluctuation moment corresponds to at least one concentration fluctuation monitoring point.

[0031] As a preferred technical solution for an automated drug dispensing system based on liquid jet swirl-enhanced stirring, the jet controller determines the drug dispensing adjustment strategy based on concentration fluctuation monitoring points at all fluctuation moments, including:

[0032] Based on the determination that the ratio of the number of multi-element fluctuation moments to the number of unit fluctuation moments is greater than a preset ratio, the injection pressure of the injection head is increased.

[0033] Based on the frequency of occurrence of all concentration fluctuation monitoring points, a frequency heat map of the dissolving tank is determined to identify areas of uneven dissolution, and the spray angle of the nozzle is adjusted to bring the spray direction closer to the center of the uneven dissolution area.

[0034] On the other hand, the present invention also provides an automated drug dispensing method based on liquid jet swirl-enhanced stirring, comprising:

[0035] Step S1: In response to the liquid level of the dissolving tank being lower than the second low level, an alarm signal is issued and a high concentration of medicine is added. In response to the end of the addition of the high concentration of medicine in the dissolving tank, the water replenishment solenoid valve is opened to replenish water into the dissolving tank to the second high level switch.

[0036] Step S2: Control the solenoid valve to the dosing state and start preparing water treatment chemicals;

[0037] Step S21: Monitor the drug concentration at each monitoring site and determine the concentration fluctuation equivalent based on the drug concentration at each monitoring site at the same time.

[0038] Step S22: Determine the concentration fluctuation time domain diagram based on the concentration fluctuation equivalent at each moment during the drug preparation process to determine the fluctuation subplot and the stationary subplot;

[0039] Step S23: Determine whether to formulate a jet adjustment strategy based on the duration of the fluctuation sub-graph;

[0040] Step S24: Determine all fluctuation moments of the fluctuation subplot and determine the concentration fluctuation monitoring points at each fluctuation moment, and determine the drug dissolution adjustment strategy based on the concentration fluctuation monitoring points;

[0041] Step S25: Based on the determination result that the concentration fluctuation equivalent in the stable subplot is less than the fluctuation threshold, it is determined that the water treatment agent has been prepared.

[0042] Step S3: In response to the determination result that the liquid level of the dosing tank is lower than the first low liquid level and the water treatment agent has been prepared, the working state of the solenoid valve is determined to be the dosing state, and the dissolution and delivery pump is controlled to start adding the agent to the dosing tank.

[0043] Step S4: Based on the liquid level of the dosing tank reaching the first high liquid level, control the solenoid valve to switch to the dosing state and control the dissolving and delivery pump to stop adding medicine to the dosing tank.

[0044] Compared with the prior art, the beneficial effects of the present invention are that the automatic drug dissolving and preparation system provided by the present invention can reduce drug dissolving time and improve drug dissolving uniformity and efficiency. By monitoring and analyzing concentration fluctuations in real time, it can adjust the spray parameters to enhance mixing, reduce deviations and avoid ineffective stirring. It also enhances automation and intelligence, completes the entire process autonomously, and reduces reliance on manual labor. Its built-in multiple mechanisms ensure stable and consistent drug preparation quality, and the linkage of various components optimizes the process continuity and reliability, ensuring that drug preparation and delivery are efficient and controllable.

[0045] In particular, this system captures the agent concentration at each point in real time through the monitoring unit, calculates the concentration fluctuation equivalent through the data processor, and generates a fluctuation time domain map based on this data, dividing it into fluctuation and stable sub-maps to accurately locate the fluctuation time and monitoring point of abnormal concentration. Combined with the fluctuation characteristics (including the proportion of fluctuation time of multiple and single elements and the frequency heat map of uneven area), the spray head angle and pressure are adjusted in a targeted manner, which can enhance the mixing effect of the swirling flow on the agent, reduce local concentration deviation, and avoid ineffective stirring, thereby improving the overall efficiency while ensuring uniform drug dissolution.

[0046] In particular, the program controller integrates data processing and injection control functions, and can complete the entire process from concentration monitoring and fluctuation analysis to strategy formulation without human intervention: by setting preset thresholds (such as fluctuation duration, fluctuation equivalent, and concentration difference) to standardize state judgment, and by using machine learning models to divide sub-maps and heat map analysis to locate uneven areas, the system can autonomously adapt to the needs of different drug dissolution stages, reduce reliance on human experience, and improve the convenience and accuracy of operation.

[0047] In particular, this system ensures the quality of drug preparation through multiple mechanisms: the liquid level switches in the dissolving tank and the dosing tank can prevent the concentration of the drug from being affected by abnormal liquid levels; the drug suction filter prevents interference from solid particles; the spray adjustment strategy is dynamically optimized based on real-time concentration data to reduce batch differences caused by fixed equipment parameters; these designs keep the drug preparation process under control, ensuring the concentration stability of different batches of water treatment agents and meeting the quality requirements for subsequent use.

[0048] In particular, this system links the dissolving tank, dosing tank, and dissolving and delivery pump through a programmable controller to form a closed-loop process of dissolving, monitoring, adjusting, and delivering the drug: the water replenishment, spraying, and suction structures of the dissolving tank and the delivery control (delivery solenoid valve) of the dosing tank work together to achieve continuous preparation and delivery of the drug in conjunction with liquid level monitoring; the angle / pressure adjustment mechanism of the spray head and the design of the circulation pipeline enhance the circulation and stirring effect of the liquid vortex, reduce the risk of pipeline blockage or drug stagnation, and improve the continuity of the overall process and the reliability of equipment operation. Attached Figure Description

[0049] Figure 1 This is a schematic diagram of an automated drug dispensing system based on liquid jet swirl-enhanced stirring, according to an embodiment of the present invention.

[0050] Figure 2 This is a flowchart illustrating the steps of an automated drug dispensing method based on liquid jet swirl-enhanced stirring, as described in an embodiment of the present invention.

[0051] In the diagram: 1, dissolving tank; 2, dosing tank; 3, dissolving and delivering pump; 4, nozzle; 5, suction filter; 61, first high level switch; 62, second high level switch; 71, first low level switch; 72, second low level switch; 8, program controller; 91, dissolving solenoid valve; 92, delivering solenoid valve. Detailed Implementation

[0052] To make the objectives and advantages of the present invention clearer, the present invention will be further described below with reference to embodiments; it should be understood that the specific embodiments described herein are merely for explaining the present invention and are not intended to limit the present invention.

[0053] Preferred embodiments of the present invention will now be described with reference to the accompanying drawings. Those skilled in the art should understand that these embodiments are merely illustrative of the technical principles of the present invention and are not intended to limit the scope of protection of the present invention.

[0054] It should be noted that in the description of this invention, the terms "upper", "lower", "left", "right", "inner", "outer", etc., which indicate directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings. This is only for the convenience of description and is not intended to indicate or imply that the device or element must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation of this invention.

[0055] Furthermore, it should be noted that, in the description of this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0056] Please see Figure 1 The diagram shows an automatic dispensing and mixing system based on liquid jet swirl enhanced stirring according to the present invention. This embodiment of the invention provides an automatic dispensing and mixing system based on liquid jet swirl enhanced stirring, including a dispensing tank 1 for dispensing water treatment agents, a dosing tank 2 connected to the dispensing tank 1 for containing the water treatment agents, and a dispensing and dispensing pump 3 connected to both the dispensing tank 1 and the dosing tank 2 for pumping the water treatment agents out.

[0057] It also includes: a monitoring unit installed inside the drug dissolving tank 1 to monitor the drug concentration at each monitoring point, and a program controller 8 connected to the drug dissolving tank 1, the drug dosing tank 2 and the drug dissolving and delivery pump respectively;

[0058] Understandably, the monitoring unit captures the spatial distribution differences of the drug concentration within the dissolving tank 1 in real time, providing a data basis for dynamically adjusting the mixing strategy. In implementation, multiple monitoring points are symmetrically arranged inside the dissolving tank 1, including the near-wall area of ​​the side wall, the central axis, the lower 1 / 3 depth of the liquid surface, and the bottom. Concentration values ​​at each point are collected synchronously using a conductivity probe or an online refractometer. Preferably, five monitoring points are arranged, one of which is located at the center point of the central axis of the dissolving tank, and the remaining four are used to simulate the stirring dead zones within the dissolving tank using fluid dynamics simulation software (such as Fluent), and four monitoring points are randomly selected from each stirring dead zone. In addition, the distance between any two monitoring points should be at least greater than 0.5 cm.

[0059] The program controller 8 includes a data processor and an injection controller;

[0060] The data processor is configured to determine the concentration fluctuation equivalent based on the drug concentration at each monitoring site at the same time.

[0061] The injection controller is used to determine the concentration fluctuation time domain diagram based on the concentration fluctuation equivalent at each moment during the drug preparation process to determine the fluctuation sub-diagram and the stable sub-diagram, to determine whether to formulate an injection adjustment strategy based on the duration of the fluctuation sub-diagram, to determine all fluctuation moments of the fluctuation sub-diagram and to determine the concentration fluctuation monitoring point at each fluctuation moment, and to determine the drug dissolution adjustment strategy based on the concentration fluctuation monitoring point.

[0062] Understandably, the injection controller identifies non-stationary phases in the mixing process and activates a dynamic adjustment mechanism accordingly. The injection controller generates a concentration fluctuation time-domain graph based on the concentration fluctuation equivalent of the entire drug preparation process in a time series. By analyzing the derivative change characteristics of the time-domain graph, such as the slope abrupt change point, it divides the graph into a fluctuation subgraph (intense mixing period) and a stationary subgraph (stable mixing period).

[0063] The drug dissolving adjustment strategy includes adjusting the injection angle and injection pressure of the injection head 4.

[0064] Understandably, through real-time analysis of concentration fluctuation equivalents and dynamic injection control, this system can autonomously suppress local concentration accumulation, shorten the dissolution cycle, and reduce reagent waste caused by uneven mixing. In addition, the spatial orientation mechanism of the injection angle effectively eliminates the bottom dead zone of traditional swirl, while the pressure step adjustment strategy takes into account both mixing efficiency and energy economy.

[0065] Specifically, the dosing tank 2 includes:

[0066] The inlet is located on the upper side wall of the dosing tank 2 and is connected to the dissolving and dispensing pump 3 via a dosing pipe for pumping water treatment agents into the dosing tank 2.

[0067] A drug delivery solenoid valve 92 is installed on the drug delivery tube;

[0068] The first liquid level switch group is used to determine the liquid level status of the dosing tank 2;

[0069] The first liquid level switch group includes a first high liquid level switch 61 and a first low liquid level switch 71, and the liquid level states include reaching the first high liquid level, being below the first low liquid level, and being between the first high liquid level and the first low liquid level; for example Figure 1 As shown, in practice, a backup dosing tank low level switch is added below the first low level switch 71 to prevent the first low level switch 71 from failing.

[0070] Specifically, the program controller 8 further includes a dosing controller, which is configured to determine the operating state of the solenoid valve based on the real-time liquid level of the dosing tank 2 to control the dissolution and delivery pump 3 to add chemicals to the dosing tank 2, including:

[0071] Based on the determination that the real-time liquid level of the dosing tank 2 is lower than the first low liquid level switch 71 and the water treatment agent has been prepared, the working state of the solenoid valve is determined to be the dosing state, and the dissolving and delivery pump 3 is controlled to start adding the agent to the dosing tank 2.

[0072] Based on the determination result that the real-time liquid level of the dosing tank 2 is at the first high liquid level switch 61, the working state of the solenoid valve is determined to be the dosing state, and the dissolution and delivery pump 3 is controlled to stop adding medicine to the dosing tank 2.

[0073] The working states include drug addition and drug preparation. The drug addition state is such that the drug delivery solenoid valve 92 is open and the drug dissolving solenoid valve 91 is closed. The drug preparation state is such that the drug dissolving solenoid valve 91 is open and the drug delivery solenoid valve 92 is closed.

[0074] In practice, the inlet of the dissolving and infusion pump 3 is connected to the suction port of the dissolving tank 1, and the outlet pipe is connected to both the circulation pipeline and the delivery pipeline through a three-way valve or a three-way solenoid valve. When the outlet of the dissolving and infusion pump 3 is connected to the circulation pipeline, it is used for the circulation and mixing of the drug solution (i.e., the drug preparation state). When the outlet of the dissolving and infusion pump 3 is connected to the delivery pipeline, it is used to transport the drug solution in the dissolving tank 1 to the dosing tank 2 (i.e., the dosing state).

[0075] It is understandable that this invention, by constructing an interlock control mechanism for dosing and preparation states, logically couples liquid level monitoring, valve actions, and pump operation, achieving autonomous and collaborative management of the entire chemical supply process. This design ensures accurate dosing of water treatment chemicals while eliminating timing conflicts between the preparation and dosing operations, significantly improving the system's operational safety and continuity.

[0076] (1) The drug delivery port is located on the upper part of the side wall of the drug delivery tank 2. By utilizing the dynamic balance principle of liquid gravity sedimentation and pressure delivery, the high-level drug delivery port forms a natural liquid seal barrier to prevent the delivered drug from flowing back into the delivery pipe, maintain the unidirectional cleanliness of the pipeline, avoid impurities deposited at the bottom of the drug delivery tank 2 from being drawn into the drug delivery path, reduce the risk of pump wear, buffer pump pressure fluctuations through gravity potential energy, and extend the service life of the dissolving and delivery pump 3.

[0077] (2) The drug delivery pipe is equipped with a drug delivery solenoid valve 92. Through the fast electrical response characteristics of the solenoid valve, it forms a hard real-time linkage with the program controller 8 to realize millisecond-level on / off control of the drug flow path, eliminate the inertial delay of the mechanical valve, establish a physical isolation barrier at the moment of state switching, ensure zero crosstalk in the drug delivery / dispensing flow path, and provide execution verification for the controller through the open / closed state feedback signal.

[0078] (3) Dual liquid level switch group (i.e., the first high / low liquid level switch) constructs a liquid level safety operation window through high and low dual threshold settings, respectively corresponding to the capacity limit boundary. The low liquid level switch triggers an early warning before the drug storage reaches the safety lower limit, reserving a buffer time for drug replenishment operation; the high liquid level switch forcibly cuts off the flow when the liquid level approaches the physical volume upper limit to prevent overflow loss; through cross-verification of independent sensing paths, control drift caused by single-point failure is avoided.

[0079] (4) Based on the logical judgment of liquid level status and drug preparation completion signal, establish an operation permission mechanism: the drug preparation status is triggered when the liquid level is low and the drug preparation is completed, ensuring that the drug preparation operation is only started after the current drug preparation cycle ends, avoiding contamination of semi-finished drugs, and preventing the empty pump operation caused by false triggering due to low liquid level through dual condition constraints; the drug preparation status is triggered only when the liquid level reaches the high limit, and automatically switches to the drug preparation process after the drug preparation is saturated, realizing seamless connection of processes, and avoiding the risk of overfilling through the liquid level hard limit protection mechanism;

[0080] (5) Using the mutual exclusion opening and closing characteristics of the solenoid valve, a physical flow path isolation is constructed. In the dosing state (i.e., the delivery valve is open and the dissolving valve is closed), the dissolving flow path is forcibly closed to ensure that the drug is injected into the dosing tank 2 in a directional manner, and to eliminate the interference of the back pressure of the dosing system on the dosing flow rate. In the dosing state (i.e., the dissolving valve is open and the delivery valve is closed), the dosing inlet is blocked to prevent the new drug from being accidentally mixed in during the dosing process, maintain the stability of the fluid dynamic field in the dissolving tank 1, and ensure the mixing efficiency.

[0081] Specifically, the dissolving tank 1 includes:

[0082] A water inlet is located at the top of the dissolving tank 1 and is used to replenish water to the dissolving tank 1. The water inlet is connected to a water source through a water supply pipe, and a normally closed water supply solenoid valve is installed on the water supply pipe.

[0083] The suction port, located on the lower side wall of the dissolving tank 1, is connected to the dissolving and delivery pump 3 via a circulation pipe for pumping outwards. It should be understood that the low-level suction port utilizes the sedimentation and aggregation characteristics of solid particles to target and extract high-concentration solutions: it prioritizes extracting supersaturated / near-saturated solutions from the bottom layer, improving the consistency of the output concentration of the dissolving and delivery pump 3; it prevents insufficiently mixed solutions from being pumped out prematurely, ensuring the stability of the finished drug's quality; and it forms a bottom-up natural circulation flow, strengthening the dynamic balance of the concentration field within the tank.

[0084] The drug suction filter 5 is connected to one end of the drug dissolving tank 1 inside the drug suction port and is used to filter solid particles. In practice, a conventional drainage filter cap or other similar structure can be used to filter some undissolved drug particles and collect the swirling drug solution evenly to promote the swirling effect.

[0085] The spray nozzle, located on the upper side wall of the dissolving tank 1, is connected to the dissolving and delivery pump 3 via a circulation pipe for pumping medicine into the dissolving tank 1. It should be understood that high-level spraying induces vortices on the liquid surface, enhances the convection exchange between the surface and deep layers of the medicine, strengthens the swirling intensity through wall constraint, accelerates the shearing and dispersion of the medicine particles, and forms a flow path separation away from the suction port, avoiding insufficient mixing caused by fluid short-circuiting.

[0086] The spray head 4, connected to the interior of the dissolving tank 1 at one end of the spray nozzle, includes an angle adjustment mechanism and a pressure adjustment mechanism. The angle adjustment mechanism is used to adjust the angle of the spray flow relative to the horizontal plane, and the pressure adjustment mechanism is used to adjust the spray flow velocity. In implementation, either the angle adjustment mechanism or the pressure adjustment mechanism can be any existing technology, as long as it can achieve the function of adjusting the spray direction and spray water pressure of the spray head. It should be understood that by changing the direction of the jet vector, the mixing dead zone in different areas can be eliminated in a targeted manner; the spray kinetic energy is dynamically matched according to the drug dissolution stage to optimize the balance between energy consumption and efficiency; the dual degrees of freedom collaboratively realize the on-demand reconstruction of the fluid dynamic field to adapt to the differences in the dissolution characteristics of multiple types of drugs; in one implementation, the spray head 4 adopts a duckbill valve-like structure, which converts the pumped cylindrical water flow into a narrow rectangular water flow and sprays it tangentially along the tank wall, so that the drug liquid in the dissolving tank 1 forms a high-speed swirling flow.

[0087] The second liquid level switch group is used to determine the liquid level status of the dissolving tank 1;

[0088] The second liquid level switch group includes a second high liquid level switch 62 and a second low liquid level switch 72. The liquid level states include reaching the second high liquid level, being below the second low liquid level, and being between the second high liquid level and the second low liquid level.

[0089] In practice, the drug dissolving solenoid valve 91 is normally open, and the drug delivery solenoid valve 92 is normally closed.

[0090] Specifically, the program controller 8 also includes a dissolving controller, used to determine the dosing time based on the real-time liquid level of the dissolving tank 1, and to control whether to add water based on the dosing end time, wherein:

[0091] The drug dissolving controller is configured to issue an alarm signal and add high-concentration drugs in response to the real-time liquid level of the drug dissolving tank 1 being lower than the second low liquid level switch 72, and to control the water replenishment solenoid valve to open in response to the end of the addition of high-concentration drugs in the drug dissolving tank 1 to replenish water to the second high liquid level switch 62.

[0092] It should be understood that the dissolving tank 1 of the present invention constructs a dynamically optimized drug dissolving environment through the combination of spatial hierarchical layout and temporal coordinated control; while ensuring mixing efficiency, it realizes autonomous coordination of key processes such as drug replenishment, circulation, filtration and spraying, significantly improving the stability of the dissolving process and the drug utilization rate, and fundamentally avoiding the risk of concentration runaway caused by disordered operation sequence in traditional drug dissolving systems.

[0093] Specifically, the data processor determines the concentration fluctuation equivalent based on the ratio of the average deviation to the average value of the drug concentration at each monitoring point at the same time, so that the injection controller can determine the concentration fluctuation time domain map based on the concentration fluctuation equivalent at each time during the drug preparation process, and divide the concentration fluctuation time domain map into a fluctuation sub-map and a stable sub-map.

[0094] It should be understood that the concentration fluctuation equivalent is determined based on the ratio of the average deviation to the average value of the drug concentration at each monitoring site at the same time. Essentially, it quantifies the dispersion of spatial concentration distribution through relative deviation: when the ratio approaches 0, it indicates that the concentration difference at each point is minimal, and the overall uniformity is high; when the ratio increases, it reflects a greater degree of local concentration deviation from the overall level. This quantification method transforms the originally abstract uniformity into a concrete numerical value, making the dynamic changes in concentration distribution during drug preparation imperceptible and measurable. This provides a clear basis for subsequent adjustment of the injection controller, avoiding reliance on experience or subjective judgment. Ambiguity; In addition, the injection controller generates a concentration fluctuation time-domain diagram based on the concentration fluctuation equivalent at each moment, that is, it associates the time dimension with the concentration fluctuation characteristics. In the time-domain diagram, the horizontal axis of time records the fluctuation change trajectory of the entire drug dispensing process, and the fluctuation equivalent value of the vertical axis intuitively presents the uniformity state of different stages. This visualization method can clearly show the start and end time, duration and strength trend of fluctuation. For example, if the fluctuation equivalent suddenly increases in a certain stage, it may correspond to local aggregation in the early stage of drug dispensing; the subsequent gradual decrease reflects the improvement of dissolution uniformity, providing a global perspective for understanding the drug dispensing mechanism and locating key stages.

[0095] In practice, if the rate of decrease of the fluctuation equivalent at several consecutive sampling times (generally 3 to 5, preferably 3) is less than 5%, it indicates that the mixing rate is slowing down, and the system is determined to enter the stationary subplot; otherwise, it still belongs to the fluctuation subplot. It should be understood that the rate of decrease = |concentration fluctuation equivalent at the current sampling time - concentration fluctuation equivalent at the previous sampling time| ÷ concentration fluctuation equivalent at the current sampling time × 100%.

[0096] Specifically, the injection controller responds to the duration of the fluctuation sub-graph being greater than a preset duration, determines and formulates an injection adjustment strategy, and identifies the moment when the concentration fluctuation equivalent in the fluctuation sub-graph is greater than the preset fluctuation equivalent as the fluctuation moment.

[0097] Specifically, the injection controller determines the concentration fluctuation monitoring points at any given time based on the difference between the agent concentration at each monitoring point and the corresponding average concentration, including:

[0098] Based on the judgment result that the difference between the drug concentration at the monitoring point and the average concentration is greater than the preset difference, the corresponding monitoring point is determined as the concentration fluctuation monitoring point;

[0099] Alternatively, based on the judgment result that the difference between the drug concentration and the average concentration at each monitoring point is less than a preset difference, the monitoring point with the largest difference between the drug concentration and the average concentration is determined as the concentration fluctuation monitoring point;

[0100] Each fluctuation moment corresponds to at least one concentration fluctuation monitoring point.

[0101] Understandably, when continuous and significant concentration fluctuations occur during the dosing process, the injection controller can accurately locate the problem monitoring point, providing a basis for subsequently developing targeted injection adjustment strategies to ensure the stability of the dosing process and the uniformity of the final drug concentration. First, the injection controller determines the duration of the fluctuation sub-graph to determine whether the current dosing process is normal. If it is not normal, an injection adjustment strategy needs to be developed. This is because short-term fluctuations may be a normal transition phenomenon in the dosing process, while prolonged fluctuations mean that there may be stable interference factors in the system, requiring intervention and adjustment. In implementation, the preset duration can be determined based on a limited number of test calibrations. The dosing process under different initial conditions (such as drug dosage and initial water temperature) is selected for monitoring. The duration of the fluctuation sub-graph during the normal transition phase is statistically analyzed, and the expected value of the duration is determined. The expected value is then increased by 10% to 15% as the preset duration.

[0102] Understandably, the moment when the concentration fluctuation equivalent in the fluctuation subplot exceeds the preset fluctuation equivalent is defined as the fluctuation moment. The preset fluctuation equivalent can be determined by linear regression analysis of the distribution of concentration fluctuation equivalents during historical qualified drug preparation processes, using the upper limit of the 80%–90% confidence interval as the standard (preferably the upper limit of the 85% confidence interval). When determining the concentration fluctuation monitoring points at the fluctuation moment, the principle is to compare the differences between the drug concentration at each monitoring point and the average concentration, identifying monitoring points with larger deviations. These points are often key areas of concentration unevenness. The preset difference can be determined in conjunction with the drug preparation process's requirements for concentration uniformity, through... A limited number of tests were conducted to assess the accuracy of concentration fluctuation monitoring point identification under different differences. The final value selected was one that accurately reflected significant deviations (accuracy greater than 90%). When the difference between the drug concentration and the average concentration at a certain monitoring point was greater than a preset difference, the monitoring point was directly identified as a concentration fluctuation monitoring point. If the difference between the drug concentration and the average concentration at all monitoring points was less than the preset difference, it indicated that the overall fluctuation was not particularly large, but the concentration fluctuation equivalent was relatively large. It was still necessary to find the point with the largest relative deviation as a control reference. In this case, the monitoring point with the largest difference was identified as the concentration fluctuation monitoring point, and it was ensured that at least one such monitoring point corresponded to each fluctuation moment.

[0103] This setup allows the injection controller to promptly identify the stages and specific locations requiring adjustment during the drug preparation process, providing clear targets for subsequent adjustments to parameters such as injection angle and speed. This, in turn, more effectively improves the uniformity of drug concentration and enhances the controllability of the drug preparation process.

[0104] Specifically, the injection controller determines the drug dissolution adjustment strategy based on the concentration fluctuation monitoring points at all fluctuation moments, including:

[0105] Based on the determination that the ratio of the number of multi-element fluctuation moments to the number of unit fluctuation moments is greater than the preset ratio, the injection pressure of the spray head 4 is increased. It should be understood that when the ratio of the number of multi-element fluctuation moments to the number of unit fluctuation moments is greater than the preset ratio, it indicates that large-scale concentration fluctuations occur frequently during the drug dissolution process. This is often due to insufficient injection pressure, resulting in insufficient flushing and mixing of the drug by the water flow, causing uneven drug dissolution in multiple areas simultaneously. In implementation, the preset ratio can be calibrated through a limited number of tests. The drug dissolution process under different injection pressures is monitored, and the ratio of the number of multi-element and unit fluctuation moments is statistically analyzed. The ratio that clearly reflects insufficient injection pressure is taken as the preset ratio. Preferably, this value is calibrated to be 1:2 through experiments. That is, when the actual ratio is greater than 1:2, the spray controller determines to increase the injection pressure of the spray head 4 to enhance the impact force and mixing capacity of the water flow and improve the uneven drug dissolution situation over a large area.

[0106] Based on the frequency of occurrence of all concentration fluctuation monitoring points, a frequency heat map of the dissolving tank 1 is determined to identify areas of uneven drug dissolution. The spray angle of the nozzle 4 is then adjusted to bring the spray direction closer to the center of these areas. It should be understood that the frequency heat map of the dissolving tank 1, determined by the frequency of occurrence of all concentration fluctuation monitoring points, represents areas with high concentration fluctuation monitoring point frequencies, which are the main areas of uneven drug dissolution. The frequency heat map visually displays the locations of these high-frequency fluctuation areas. In practice, analysis shows that when the frequency of concentration fluctuation monitoring points in a certain area exceeds 30%, that area is identified as an area of ​​uneven drug dissolution. After identifying the areas of uneven drug dissolution, the spray angle of the nozzle 4 is adjusted to bring the spray direction closer to the center of that area. This allows the water flow to act more directly on the areas of uneven drug dissolution, enhancing the mixing and dissolution of the drug with the water, thereby improving the uneven drug dissolution situation.

[0107] In practice, a multi-variable fluctuation moment refers to a situation where there are multiple concentration fluctuation monitoring points at a single fluctuation moment, while a single-variable fluctuation moment refers to a situation where there is only one concentration fluctuation monitoring point at a single fluctuation moment.

[0108] It should be understood that this invention enables the injection controller to formulate a precise drug dissolution adjustment strategy based on the concentration fluctuation monitoring point information at the time of fluctuation, thereby specifically solving the unevenness problem that occurs during the drug dissolution process and improving the overall drug dissolution effect. Through this setting, the injection controller can take corresponding adjustment measures according to different fluctuation conditions. Increasing the injection pressure can cope with large-scale drug dissolution unevenness, and adjusting the injection angle can accurately solve the drug dissolution problem in specific areas, thereby effectively improving the uniformity and efficiency of the drug dissolution process.

[0109] Please see Figure 2 The diagram illustrates the steps of an automated drug dispensing method based on liquid jet swirl-enhanced stirring according to an embodiment of the present invention. An automated drug dispensing method based on liquid jet swirl-enhanced stirring is also provided, comprising:

[0110] Step S1: In response to the liquid level of the dissolving tank 1 being lower than the second low liquid level, an alarm signal is issued and a high concentration of medicine is added. In response to the end of the addition of the high concentration of medicine to the dissolving tank 1, the water replenishment solenoid valve is opened to replenish water to the dissolving tank 1 to the second high liquid level switch 62 (i.e., the liquid level of the dissolving tank 1 has reached the second high liquid level).

[0111] Step S2: Control the solenoid valve to the dosing state and start preparing water treatment chemicals;

[0112] Step S21: Monitor the drug concentration at each monitoring site and determine the concentration fluctuation equivalent based on the drug concentration at each monitoring site at the same time.

[0113] Step S22: Determine the concentration fluctuation time domain diagram based on the concentration fluctuation equivalent at each moment during the drug preparation process to determine the fluctuation subplot and the stationary subplot;

[0114] Step S23: Determine whether to formulate a jet adjustment strategy based on the duration of the fluctuation sub-graph;

[0115] Step S24: Determine all fluctuation moments of the fluctuation subplot and determine the concentration fluctuation monitoring points at each fluctuation moment, and determine the drug dissolution adjustment strategy based on the concentration fluctuation monitoring points;

[0116] Step S25: Based on the determination result that the concentration fluctuation equivalent in the stable subplot is less than the fluctuation threshold, it is determined that the water treatment agent has been prepared.

[0117] Step S3: In response to the determination result that the liquid level of the dosing tank 2 is lower than the first low liquid level and the water treatment agent has been prepared, the working state of the solenoid valve is determined to be the dosing state, and the dissolution and delivery pump 3 is controlled to start adding the agent to the dosing tank 2.

[0118] Step S4: Based on the determination that the liquid level of the dosing tank 2 has reached the first high liquid level, the working state of the solenoid valve is switched to the dosing state, and the dissolution and delivery pump 3 is stopped from adding medicine to the dosing tank 2.

[0119] The technical solution of the present invention has been described above with reference to the preferred embodiments shown in the accompanying drawings. However, it will be readily understood by those skilled in the art that the scope of protection of the present invention is obviously not limited to these specific embodiments. Without departing from the principles of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will all fall within the scope of protection of the present invention.

[0120] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention. Various modifications and variations can be made to the present invention by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the scope of protection of the present invention.

Claims

1. An automatic dispensing and mixing system based on liquid jet swirl enhanced stirring, comprising a dispensing tank for dispensing water treatment agents, a dosing tank connected to the dispensing tank and for containing the water treatment agents, and a dispensing and dispensing pump connected to the dispensing tank and the dosing tank respectively and for pumping out the water treatment agents; Its features are, Also includes: A monitoring unit installed inside the drug dissolving tank to monitor the drug concentration at each monitoring point; and a programmable controller connected to the drug dissolving tank, the drug dosing tank, and the drug dissolving and delivery pump, respectively. The program controller includes a data processor and an injection controller; The data processor is configured to determine the concentration fluctuation equivalent based on the ratio of the average deviation to the average value of the drug concentration at each monitoring site at the same time. The injection controller is used to determine a concentration fluctuation time-domain graph based on the concentration fluctuation equivalent at each moment during the drug preparation process, and divide the concentration fluctuation time-domain graph into a fluctuation subgraph and a stable subgraph. Based on the determination that the duration of the fluctuation subgraph is greater than a preset duration, an injection adjustment strategy is formulated. The moment in the fluctuation subgraph where the concentration fluctuation equivalent is greater than the preset fluctuation equivalent is determined as a fluctuation moment. The concentration fluctuation monitoring point at any fluctuation moment is determined based on the difference between the drug concentration at each monitoring point and the corresponding average concentration. This includes: Based on the judgment result that the difference between the drug concentration at the monitoring point and the average concentration is greater than the preset difference, the corresponding monitoring point is determined as the concentration fluctuation monitoring point; Alternatively, based on the judgment result that the difference between the drug concentration and the average concentration at each monitoring point is less than a preset difference, the monitoring point with the largest difference between the drug concentration and the average concentration is determined as the concentration fluctuation monitoring point; Furthermore, the injection controller determines the drug dissolution adjustment strategy based on the concentration fluctuation monitoring points; Each fluctuation moment corresponds to at least one concentration fluctuation monitoring point, and the drug dissolution adjustment strategy includes adjusting the injection angle and injection pressure of the injection head.

2. The automated drug dispensing system based on liquid jet swirl-enhanced stirring according to claim 1, characterized in that, The dosing tank includes: The inlet is located on the upper side wall of the dosing tank and is connected to the dissolving and dispensing pump via a dosing pipe to pump water treatment agents into the dosing tank. A drug delivery solenoid valve is installed on the drug delivery tube; The first level switch group is used to determine the level status of the dosing tank; The first liquid level switch group includes a first high liquid level switch and a first low liquid level switch, and the liquid level state includes reaching the first high liquid level, being below the first low liquid level, and being between the first high liquid level and the first low liquid level.

3. The automated drug dispensing system based on liquid jet swirl-enhanced stirring according to claim 1, characterized in that, The dissolving tank includes: A water inlet is located at the top of the dissolving tank and is used to replenish water to the dissolving tank. The suction port is located on the lower part of the side wall of the dissolving tank and is connected to the dissolving and delivery pump through a circulation pipe for pumping the drug outward; A drug-absorbing filter, which is connected to one end of the drug-dissolving tank inside the drug-absorbing port, is used to filter solid particles; The spray nozzle is located on the upper side wall of the dissolving tank and is connected to the dissolving and delivery pump through a circulation pipe to pump the drug into the dissolving tank. The spray head, which is connected to the inside of the dissolving tank of the spray nozzle, includes an angle adjustment mechanism and a pressure adjustment mechanism. The angle adjustment mechanism is used to adjust the angle of the spray flow relative to the horizontal plane, and the pressure adjustment mechanism is used to adjust the spray flow rate. The second liquid level switch group is used to determine the liquid level status of the dissolving tank; The second liquid level switch group includes a second high liquid level switch and a second low liquid level switch, and the liquid level states include reaching the second high liquid level, being below the second low liquid level, and being between the second high liquid level and the second low liquid level.

4. The automated drug dispensing system based on liquid jet swirl-enhanced stirring according to claim 1, characterized in that, The injection controller determines the drug dissolution adjustment strategy based on the concentration fluctuation monitoring points at all fluctuation times, including: Based on the determination that the ratio of the number of multi-element fluctuation moments to the number of unit fluctuation moments is greater than a preset ratio, the injection pressure of the injection head is increased. Based on the frequency of occurrence of all concentration fluctuation monitoring points, a frequency heat map of the dissolving tank is determined to identify areas of uneven dissolution, and the spray angle of the nozzle is adjusted to bring the spray direction closer to the center of the uneven dissolution area.

5. An automated drug dispensing method based on liquid jet swirl-enhanced stirring, applied to the automated drug dispensing system based on liquid jet swirl-enhanced stirring as described in any one of claims 1-4, characterized in that, include: Step S1: In response to the liquid level of the dissolving tank being lower than the second low liquid level switch, an alarm signal is issued and a high concentration of medicine is added. In response to the end of the addition of the high concentration of medicine in the dissolving tank, the water replenishment solenoid valve is opened to replenish water into the dissolving tank to the second high liquid level switch. Step S2: Control the solenoid valve to the dosing state and start preparing water treatment chemicals; Step S21: Monitor the drug concentration at each monitoring site and determine the concentration fluctuation equivalent based on the drug concentration at each monitoring site at the same time. Step S22: Determine the concentration fluctuation time domain diagram based on the concentration fluctuation equivalent at each moment during the drug preparation process to determine the fluctuation subplot and the stationary subplot; Step S23: Determine whether to formulate a jet adjustment strategy based on the duration of the fluctuation sub-graph; Step S24: Determine all fluctuation moments of the fluctuation subplot and determine the concentration fluctuation monitoring points at each fluctuation moment, and determine the drug dissolution adjustment strategy based on the concentration fluctuation monitoring points; Step S25: Based on the determination result that the concentration fluctuation equivalent in the stable subplot is less than the fluctuation threshold, it is determined that the water treatment agent has been prepared. Step S3: In response to the determination result that the liquid level of the dosing tank is lower than the first low liquid level and the water treatment agent has been prepared, the working state of the solenoid valve is determined to be the dosing state, and the dissolution and delivery pump is controlled to start adding the agent to the dosing tank. Step S4: Based on the liquid level of the dosing tank reaching the first high liquid level, control the solenoid valve to switch to the dosing state and control the dissolving and delivery pump to stop adding medicine to the dosing tank.

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